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NEW DRUGS-BiolimusA9 incorporated with new stent technology (DEVAX,XStent) In-Stent Late Loss (mm) 4 months 6-8 months 12 months Sirolimus 0.09 REALITY* Sirolimus/heparin 0.27 Everolimus 0.10 - 0.11 0.24 Biolimus-A9 0.17- 0.15 Zotarolimus 0.12 Tacrolimus 0.67 Harmony* SPIRIT-I/ / II* STEALTH / NOBORI RESOLUTE JUPITER-II II * *QCA analysis (1st or 2nd reading) by Cardialysis in Rotterdam
NEW DRUGS-BiolimusA9 incorporated with the Xtent technology Delivery System Sheath protected Adjustable balloon length Multiple deployments Stent Interdigitated 6mmCoCrsegments Lengths: 60mm & 36mm Diameters: 2.5, 3.0 & 3.5mm Drug Coating Biolimus A9 ® Biodegradable Drug Carrier (PLA)
Page 1 and 2: DES: NEW GENERATION OF STENTS and N
Page 3 and 4: 1 st endpoint: Death, MI 2 nd endpo
Page 5 and 6: 1 st endpoint: Death, MI 2 nd endpo
Page 7 and 8: Survey of the next generation of dr
Page 9 and 10: NEW COATING, NO COATING, ABSORABLE
Page 11 and 12: # 1 The # New “high durable tech
Page 13 and 14: This new coating decreases the usua
Page 15 and 16: Enhances the Expression of eNOS mRN
Page 17 and 18: # Porous and micro-porous Porous St
Page 19 and 20: # Porous and micro-porous Nanocarbo
Page 23 and 24: #2 BIOABSORBABLE METAL STENT in Mag
Page 25 and 26: #2 BIOABSORBABLE METAL STENT WITH D
Page 27 and 28: Late Loss 100 80 60 40 20 EES ** :
Page 29 and 30: ACC 2007 Clinical Results Hierarchi
Page 31 and 32: The LIMUS Family of Drugs In-Stent
Page 33 and 34: The LIMUS Family of Drugs - more of
Page 35: The LIMUS Family of Drugs - more of
Page 41 and 42: NEW BIOLOGICAL TARGET NEW DRUGS-TAC
Page 43 and 44: # 4 NEW BIOLOGICAL TARGET- NEW DRUG
Page 45 and 46: CARBOSTENT SRT: The Platform Stent
Page 49 and 50: # ABSORBABLE COATING in Heparinized
Page 51 and 52: #5 DUAL ELUTION HEPARIN AND SIROLIM
Page 53 and 54: # 5 NEW BIOLOGICAL TARGET- NEW DRUG
Page 55 and 56: #5 DUAL ELUTION PACLITAXEL AND PIME
Page 59 and 60: #6 ENDOTHELIAL PROGENITOR CELL CAPT
Page 61 and 62: late loss QCA (mm) ENDOTHELIAL PROG
Page 65 and 66: The ultimate dream is to produce a
Page 67 and 68: ENDOTHELIAL PROGENITOR CELL CAPTURE
Page 71 and 72: Today, we can non-invasively diagno
Page 73 and 74: BIOABSORBABLE DES Today, we can non
Page 75 and 76: ENDOTHELIAL PROGENITOR CELL CAPTURE
Page 77 and 78: NEW BIOLOGICAL TARGET NEW DRUGS-Bio
Page 79 and 80: #2 DUAL ELUTION ZOTAROLIMUS AND DEX
Page 81: #2 BIOABSORBABLE DES Bioabsorbable

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