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Gleason grading system

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Clinical implications of the modified<br />

<strong>Gleason</strong> <strong>grading</strong> <strong>system</strong><br />

The true test of the validity of the 2005 ISUP<br />

Modified <strong>Gleason</strong> System is its correlation with<br />

patient outcome<br />

Studies by Uemura et al. (2009) and Billis et al.<br />

(2008) demonstrated that the <strong>Gleason</strong> scores on<br />

needle biopsies using the modified but not the<br />

original <strong>Gleason</strong> <strong>system</strong> correlated with progression<br />

after radical prostatectomy

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