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Gleason grading system

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Subsequent (2010) proposals for slight<br />

modifications of the ISUP <strong>grading</strong> <strong>system</strong><br />

All cribriform patterns are diagnosed<br />

as <strong>Gleason</strong> pattern 4 rather than<br />

pattern 3<br />

Glomerulations most likely represent<br />

an early stage of cribriform pattern 4<br />

cancer and should likely be graded as<br />

pattern 4

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