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McGill University - Canada MEG Consortium

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<strong>MEG</strong> Training Workshop<br />

organized by the <strong>Canada</strong> <strong>MEG</strong> <strong>Consortium</strong><br />

followed by a Brainstorm Hands-on Training Course<br />

November 17-18<br />

November 19, 2011<br />

Montréal Neurological Institute – <strong>McGill</strong> <strong>University</strong><br />

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- <strong>MEG</strong> Training Workshop & Course, p.1 -


<strong>MEG</strong> Training Workshop<br />

organized by the <strong>Canada</strong> <strong>MEG</strong> <strong>Consortium</strong><br />

followed by a Brainstorm Hands-on Training Course<br />

November 17-18<br />

November 19, 2011<br />

Location:<br />

Objectives:<br />

Montreal Neurological Institute, <strong>McGill</strong> <strong>University</strong>, 3801 <strong>University</strong> st., Montréal, QC<br />

This two-day training workshop is an initiative of the <strong>Canada</strong> <strong>MEG</strong> <strong>Consortium</strong> (CMC) to promote<br />

and disseminate magnetoencephalography (<strong>MEG</strong>) as a brain imaging technique, in <strong>Canada</strong> an<br />

beyond. The CMC regroups the 6 Canadian <strong>MEG</strong> centres as a joint academic network and <strong>MEG</strong><br />

task force for access, education, shared expertise and instrument and software resources about<br />

<strong>MEG</strong>, for neuroscience and neuroimaging investigators.<br />

This first training workshop has the following objectives:<br />

1) To educate investigators who are new to brain imaging, and to <strong>MEG</strong> in particular about the<br />

possibilities offered by <strong>MEG</strong> as a brain functional imaging technique;<br />

2) To expose the conceptual foundations of <strong>MEG</strong> signal analysis and imaging;<br />

3) To clarify the typical workflow for <strong>MEG</strong> data analysis<br />

4) To provide a first, elementary hands-on experience with data acquisition and analysis<br />

5) To incite investigators to consider <strong>MEG</strong> as the modality of choice for their research projects.<br />

Brainstorm hands-on training course: The CMC training will be immediately followed by a Brainstorm hands-on<br />

training course (joint or separate registration required), where attendees will be able to extensively<br />

go through multiple practical aspects of <strong>MEG</strong> signal analysis and source imaging, using Brainstorm<br />

(attendees are encouraged to bring their own laptops; PCs will also be available).<br />

Targeted audience: Investigators (faculty, research associates and students) new to neuroimaging or to <strong>MEG</strong> in<br />

particular, willing to learn about <strong>MEG</strong> as a potential modality of choice for their clinical or cognitive<br />

neuroscience studies. An emphasis will be made on the complementarity of <strong>MEG</strong> with functional<br />

MRI (fMRI) and EEG.<br />

Registration:<br />

CMC + Brainstorm courses (3 days):<br />

CMC 2-day workshop only:<br />

Brainstorm course only:<br />

$45 (students and post-docs); $75 (faculty)<br />

$30 (students and post-docs); $45 (faculty)<br />

$30 (students & post-docs) ; $45 (faculty)<br />

• Taxes not included for non <strong>McGill</strong> participants<br />

• Includes access to teaching material (slides)<br />

• Free coffee !<br />

• Lunch on your own (many options on and around <strong>McGill</strong>'s campus)<br />

• Non refundable<br />

• Registration is open until the roster of 75 available seats is filled<br />

- <strong>MEG</strong> Training Workshop & Course, p.2 -


Program: CMC Training Workshop<br />

Day 1: November 17, 2011<br />

Location:<br />

de Grandpré Communication Centre, Montreal Neurological Institute; 3801 <strong>University</strong> St., Montréal.<br />

Follow signage and/or visit http://neuromedia.mcgill.ca/mnibooking/facdirections/dgccdir.htm<br />

Morning – Concepts and foundations<br />

08:00 – 08:30: Welcome, coffee & registration<br />

08:30 – 08:45 Forewords<br />

Sylvain Baillet, MNI, <strong>McGill</strong> <strong>University</strong><br />

08:45 – 09:00 Presentation of the CMC initiative<br />

Pierre Jolicoeur, <strong>University</strong> of Montreal<br />

Doug Cheyne, SickKids Toronto<br />

09:00 – 09:45 Physiological origins of <strong>MEG</strong> signals<br />

Neural sources of electromagnetic fields detected by <strong>MEG</strong> & EEG; specificity of <strong>MEG</strong><br />

Sylvain Baillet, MNI, <strong>McGill</strong> <strong>University</strong><br />

09:45 – 10:15 <strong>MEG</strong> instrumentation & environment<br />

Interfacing with the system; acquisition parameters; recording with EEG, subject preparation<br />

Tim Bardouille, National Research Council, IWK, Halifax<br />

10:15 – 10:30 COFFEE BREAK<br />

10:30 – 11:15 Paradigm design<br />

Detection of event-related evoked, induced and steady-sate responses<br />

Bernhard Ross, Rotman Research Institute, Baycrest<br />

11:15 – 12:00 <strong>MEG</strong> source imaging<br />

Understanding the forward and the inverse source estimation problems<br />

Christophe Grova, <strong>McGill</strong> <strong>University</strong><br />

12:00 – 12:45 Roundtable, floor open to questions<br />

12:45 – 14:30 LUNCH<br />

13:30 - 14:30: Laptop Clinic @ The McConnell Brain Imaging Centre, <strong>MEG</strong> Suite<br />

We will provide technical assistance to attendees for software installation of Day 2 (Nov<br />

18) and the Brainstorm course (Nov 19)<br />

- <strong>MEG</strong> Training Workshop & Course, p.3 -


Program: CMC Training Workshop<br />

Day 1: November 17, 2011<br />

Location:<br />

de Grandpré Communication Centre, Montreal Neurological Institute; 3801 <strong>University</strong> St., Montréal.<br />

Follow signage and/or visit http://neuromedia.mcgill.ca/mnibooking/facdirections/dgccdir.htm<br />

Afternoon – <strong>MEG</strong> in practice<br />

14:30 – 15:00 Clinical <strong>MEG</strong><br />

A brief overview of its application in epilepsy patients<br />

Eliane Kobayashi, MNI, <strong>McGill</strong> <strong>University</strong><br />

15:00 – 15:30 Auditory processes<br />

Bernhard Ross, Rotman Research Institute, Baycrest<br />

15:30 – 16:00 Sensorimotor processes<br />

Doug Cheyne, SickKids, Toronto<br />

16:00 – 16:15 COFFEE BREAK<br />

16:15 – 17:00 Attention and Cognition<br />

Pierre Jolicoeur, <strong>University</strong> of Montreal<br />

17:00 – 17:30 Neural oscillations, connectivity: perspectives on pathology<br />

Urs Ribary, Simon Fraser <strong>University</strong><br />

17:30 – 18:00 Open discussion<br />

18:30 – 20:30 Participants are welcome to attend the Neuro Film Series featuring “The Commitments”,<br />

hosted by Prof Alan C. Evans (this is a free event; pop-corn & snacks not included)<br />

http://neuroevents.mcgill.ca/index.php?page=neuro-film-series<br />

Other social event of interest: Steven Pinker lecture and book signing<br />

Steven Pinker, Johnstone Family Professor in the Department of Psychology at Harvard<br />

<strong>University</strong>, celebrated author, and <strong>McGill</strong> alumnus, will be speaking about his new book,<br />

The Better Angels of Our Nature: Why Violence has Declined. The talk will take place at<br />

New Residence Hall, 3625 Avenue du Parc, at 7 p.m. (doors open at 6:30). Admission is<br />

$2 for students, $5 for the general public, and $40 for a ticket plus a copy of the book.<br />

Tickets are on sale at the <strong>McGill</strong> Bookstore, 3420 McTavish St. To reserve tickets and pay at<br />

the door, call 514-398-3222 or email events.bookstore@mcgill.ca. Space is limited. For<br />

more information, visit www.mcgill.ca/channels/events/item/?item_id=211513<br />

18:00 – 19:00 Technical meeting (workshop faculty only)<br />

19:30 – Late CMC Business Meeting.<br />

All attendees are welcome to join us after 20:30 @ L'ASSOMMOIR, 211 Notre-Dame Ouest<br />

- <strong>MEG</strong> Training Workshop & Course, p.4 -


Program: CMC Training Workshop<br />

Day 2: November 18, 2011<br />

Location:<br />

Groups Green - Blue - Yellow: Faculty Club ballroom (3450 McTavish, <strong>McGill</strong> <strong>University</strong>)<br />

Group Red meets at the <strong>MEG</strong> Lab, at The Neuro, (3801 <strong>University</strong> St.)<br />

The day is dedicated to hands-on experience with data acquisition and basic data analysis. The attendees will be<br />

shuffled in 4 groups, which will rotate through the <strong>MEG</strong> lab session (1.5H) while spending the rest of the day<br />

learning the foundations of data review and analysis using their own laptops (directions for software installation<br />

are on CMC website: http://www.canada-meg-consortium.org/EN/InstallCtf + see our laptop clinic below).<br />

08:00 – 09:00 Laptop Clinic & Breakfast @ Faculty Club Ballroom<br />

Although attendees are expected to install the software and tutorial data before attending the<br />

meeting, the workshop staff will help those in need of technical assistance get ready for the<br />

software session. Participants are encouraged to contact francois.tadel@mcgill.ca for technical<br />

issues before the meeting dates.<br />

Starting at 09:00<br />

<strong>MEG</strong> Lab Rotation @ <strong>McGill</strong> <strong>MEG</strong> Suite, McConnell Brain Imaging Centre, MNI<br />

Break-up group of 17 participants<br />

Group Red: 09:00 – 10:30 Group Green: 10:30-12:00<br />

Group Blue: 13:30-15:00 Group Yellow: 15:00-16:30<br />

Practice of <strong>MEG</strong> data acquisition<br />

Recording of basic visual and somatosensory responses, including, options for subject preparation,<br />

stimulus presentation, setting-up acquisition parameter, data acquisition, basic data review for<br />

quality control.<br />

12:00 – 13:30 LUNCH<br />

Beth Bock, Esther Florin & François Tadel (MNI, <strong>McGill</strong>)<br />

Hands-on, data analysis @ Faculty Club Ballroom<br />

Practice of data reviewing & basic processing<br />

The goal of this session is to provide new users with a first hands-on experience with reviewing<br />

and analyzing <strong>MEG</strong> data. We will essentially feature the CTF software suite, which exemplifies well<br />

the <strong>MEG</strong> software experience. Topics to be covered include: reviewing data quality, filtering, artifact<br />

detection & correction, trial averaging, sensor topography plots, basic source analysis (dipole<br />

fitting).<br />

Teresa Cheung & Alex Moiseev (Simon Fraser <strong>University</strong>) & Sylvain Baillet (<strong>McGill</strong>)<br />

13:30 – 16:30 Lab rotation and software session resume<br />

16:30 – 16:45 COFFEE BREAK<br />

16:45 – 17:30 (Lecture @ Faculty Club Ballroom) Beamforming source imaging using SAM and erSAM<br />

This lecture will briefly review the spatial filtering method of source imaging for <strong>MEG</strong> data, and<br />

provide some hands-on experience using the Synthetic Aperture Magnetometry (SAM) tools in the<br />

CTF software suite, as well as the spatiotemporal beamforming (erSAM) technique.<br />

Douglas Cheyne, SickKids, Toronto & Teresa Cheung, Simon Fraser <strong>University</strong><br />

- <strong>MEG</strong> Training Workshop & Course, p.5 -


Brainstorm <strong>MEG</strong>/EEG Imaging Course<br />

Saturday, November 19, 2011<br />

Organized by:<br />

The <strong>MEG</strong> Program @ <strong>McGill</strong><br />

Location:<br />

de Grandpré auditorium<br />

3801 <strong>University</strong> St.<br />

Montreal Neurological Institute<br />

<strong>McGill</strong> <strong>University</strong><br />

Montréal, QC<br />

Objectives: We are opening a new software course series dedicated to the training of investigators with the<br />

utilization of Brainstorm, a comprehensive academic software suite for the processing and visualization of <strong>MEG</strong><br />

(magnetoencephalography) and EEG data, with an emphasis on functional brain imaging.<br />

The course will consist of a one-day hands-on session, with the primary objective of getting new users familiar<br />

with the software features, in coordination with their research questions. The goal is to help Brainstorm users<br />

reach maximum productivity with their experimental data and learn to identify and use the tools who are the most<br />

able to address their research needs.<br />

Targeted audience:<br />

Investigators (faculty, research associates and students) using <strong>MEG</strong> and/or EEG in their experimental research,<br />

with a strong interest in imaging neural sources of brain activity from scalp recordings.<br />

Registration:<br />

CMC + Brainstorm course (3 days) $45 (students and post-docs); $75 (faculty)<br />

CMC 2-day workshop only $30 (students and post-docs); $45 (faculty)<br />

Brainstorm course only $30 (students & post-docs) ; $45 (faculty)<br />

Includes coffee breaks and course material (slides)<br />

Requirements:<br />

All attendees must bring and use their own laptop during the hands-on training, with Matlab 2007 or later<br />

version installed. Alternatively, PC users can use an executable version of BrainStorm, which does not require<br />

Matlab. Mac users can also run this executable version through Wine or similar PC emulation program (please<br />

contact francois.tadel@mcgill.ca for technical assistance, prior to the session).<br />

Useful links:<br />

Attendance inquiries: sylvain.baillet@mcgill.ca<br />

<strong>McGill</strong> <strong>MEG</strong> pages:<br />

http://www.bic.mni.mcgill.ca/ResearchLabsNeuroSPEED/HomePage<br />

- <strong>MEG</strong> Training Workshop & Course, p.6 -


Faculty (McConnell Brain Imaging Centre, MNI):<br />

Sylvain Baillet<br />

Director, <strong>MEG</strong> Research<br />

Beth Bock Francois Tadel Esther Florin<br />

<strong>MEG</strong> System Manager <strong>MEG</strong> Software Engineer Research Associate<br />

Program:<br />

08:00 – 09:00 Laptop Clinic & Breakfast: We will help those in need of technical assistance get ready for<br />

the session. Participants are encouraged to contact francois.tadel@mcgill.ca for technical<br />

issues encountered before the meeting.<br />

09:00 – 09:15 Welcome and introduction to the faculty<br />

09:15 – 10:00 <strong>MEG</strong>, EEG imaging crash course<br />

Concepts, terminology, essential elements<br />

(Sylvain Baillet)<br />

10:00 – 10:45 The BrainStorm architecture and typical data workflow (François Tadel)<br />

10:45 – 11:00 COFFEE BREAK<br />

11:00 – 12:30 Hands-on begins and will take attendees through a step-by-step tutorial covering:<br />

(the <strong>MEG</strong> @ <strong>McGill</strong> team)<br />

1. First essential steps<br />

Installation, defining a database, data organization<br />

2. MRI integration<br />

Registration of MRI volumes with <strong>MEG</strong> source space, quality control<br />

3. Importing <strong>MEG</strong>/EEG recordings<br />

Understanding data formats, channel information, basic pre-processing<br />

4. Exploring data: recordings<br />

Time series visualization, sensor topography, defining components, event marking and detection,<br />

event-related averaging<br />

5. Head Modeling<br />

Forward modeling of distributed source models: 3D volume, cortically-constrained<br />

6. Source estimation<br />

Inverse modeling, understanding basic model parameters<br />

7. Exploring source maps<br />

3D visualization, define regions of interests, work with brain atlases, export source time series<br />

8. Time-frequency analysis<br />

Tools for computing time-frequency decompositions of source and sensor time series<br />

9. Statistics<br />

Group studies, intersubject registration, descriptive and inference statistics<br />

10.Processes: Graphical batching interface<br />

Build your own processing pipeline; tools for generating scripts<br />

12:30 – 13:30 Lunch break<br />

13:30 – 15:00 Hands-on continues<br />

15:00 – 15:30 COFFEE BREAK<br />

15:30 – 16:30 Hands-on continues<br />

16:30 – 17:30 Discussion, miscellaneous support<br />

- <strong>MEG</strong> Training Workshop & Course, p.7 -

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