Toxicology - Office of the Provost and Executive Vice President for ...

TEXAS A&M 

UNIVERSITY 

Interdisciplinary 

Faculty 

of 

Toxicology 

May 2007

2007 Toxicology External Review i 

TABLE OF CONTENTS 

1. INTRODUCTION 

A. Welcome from the Interdisciplinary Faculty of Toxicology Chair . . . . . . . . . . 1 

B. Charge to the Review Team . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 

2. PROGRAM OVERVIEW 

A. Texas A&M University. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 

B. Interdisciplinary Faculties . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 

C. Development of the IFT and Related Centers and Programs . . . . . . . . . . . 3 

1. Toxicology Training Grant . . . . . . . . . . . . . . . . . . . . . . . . . . 5 

2. Superfund Basic Research Program . . . . . . . . . . . . . . . . . . . . . 5 

3. Center for Environmental and Rural Health . . . . . . . . . . . . . . . . . 6 

4. Partnership for Environmental Education and Rural Health . . . . . . . . . 6 

5. IFT Executive Committee and Chairs . . . . . . . . . . . . . . . . . . . . 8 

D. Administrative Structure of the IFT. . . . . . . . . . . . . . . . . . . . . . . . . 9 

E. Previous Program Review and Changes in the Past Five Years . . . . . . . . . 10 

1. Previous Program Review. . . . . . . . . . . . . . . . . . . . . . . . . . 10 

2. Changes in the IFT since the previous review. . . . . . . . . . . . . . . . 11 

F. Budget Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 

1. Funding Allocations . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13 

2. Expenditures. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 

G. Evaluation and Needs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 

3. VISION AND GOALS 

A. Vision 2020 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 

B. Mission of the IFT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 

C. Vision . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

D. Strategic Plan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

1. Goals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

2. Action Plans. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

3. External Factors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 

E. Connection to the Vision, Goals, Mission, and Objectives of Vision 2020. . . . . 19 

4. THE GRADUATE PROGRAM 

A. Application Process . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 

B. Assistantship Funding. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 

C. Degree Requirements and Coursework. . . . . . . . . . . . . . . . . . . . . . 21 

1. Core Courses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

2. Elective Courses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

3. Enrichment Activities . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 

D. Students . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

1. Current Student Profile (Fall 2006). . . . . . . . . . . . . . . . . . . . . . 25 

2. Applicant Profile, 1998-2006 . . . . . . . . . . . . . . . . . . . . . . . .26 

3. Former Students, 1998-2006 . . . . . . . . . . . . . . . . . . . . . . . . 27 

E. Benchmarks Used by the IFT to Determine Whether Goals Are Being Met. . . . 29 

F. Documentation of Student Learning/Learning Outcomes . . . . . . . . . . . . . 30 

G. Student Input to the Review . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

H. Facilities for Research and Research Training . . . . . . . . . . . . . . . . . . . . 31

ii 

2007 Toxicology External Review 

5. THE FACULTY 

A. Current Faculty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 

B. Faculty Profile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 

C. IFT Involvement in Teaching . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 

D. Research Support of IFT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 

E. Joint Programs and Collaborative Research Projects with Other Units. . . . . . 35 

F. Areas of Outstanding Performance . . . . . . . . . . . . . . . . . . . . . . . . 35 

G. Faculty Salaries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 

6. STRENGTHS AND WEAKNESSES OF THE IFT 

A. Program Strengths . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 

1. Graduate Education. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 

2. Research . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

3. Administration. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

B. Program Weaknesses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 

LIST OF APPENDICES 

A. Administrative Framework for Interdisciplinary Programs 

B. 2006 PEER Perspectives: Broadening the Reach of University Resources by 

Advancing STEM (Science, Technology, Engineering and Mathematics) 

C. IFT Bylaws 

D. Duties of Administrative Assistant 

E. IFT Seminar Series 1998-Present 

F. Annual Report of the IFT (January 1, 2005 through April 30, 2006) 

G. Trainee Conference Participation and Highlights (1998-2006) 

H. Current Student Awards and Honors 

I. Faculty Awards and Honors 

J. Faculty Biosketches 

K. Current Student Publications 

L. Outcomes Assessment of the Toxicology Program Administered Through the IFT 

M. Typical Seminar Speaker Schedule 

N. Graduate Student Survey of the IFT 

O. IFT Faculty Roster 

P. Courses Taught by IFT Faculty 

Q. Research support of IFT

2007 Toxicology External Review 1 

1. INTRODUCTION 

1.A. Welcome from the Interdisciplinary Faculty of Toxicology Chair 

The Interdisciplinary Faculty of Toxicology (IFT) welcomes you to Texas A&M University 

(TAMU) and thanks you for your service as external reviewers of our graduate program. We are 

pleased to have this opportunity to assess our program and look for opportunities to continue to 

improve and enhance it. We realize that a strong research and graduate program, and in 

particular a strong doctoral program, is a key part of creating and maintaining an excellent 

interdisciplinary faculty and in establishing and enhancing our academic reputation. Thus, we 

are grateful for your help in this process. 

This self-study report was prepared for this review and reflects an evaluation of the graduate 

program. It includes a brief overview of TAMU, an introduction to origin and organization of 

TAMU Interdisciplinary Faculties, and a brief history and background of the IFT, including 

information on our faculty, students, and facilities. It provides details of the graduate curriculum 

and information about the program. Research areas within the IFT are presented, as these 

form the basis for the doctoral program. An internal assessment and overview of future plans 

are provided as direction for the program. 

We look forward to your feedback and await your recommendations about how we might 

improve our program as we strive for excellence. We realize this is a time-consuming task and 

thank you again for your service. We will be glad to answer any questions you might have and 

provide any additional information you might need. 

1.B. Charge to the Review Team 

Dr. John R. Giardino, Dean of Graduate Studies, requests that the review team examine the 

doctoral program within the Toxicology Faculty using the materials provided, along with any 

additional information you might request. While evaluating the existing program, please consider 

the allocation of resources, (i.e., human and fiscal) within the Program, the absolute level of 

support the Program receives from the University, and comment as appropriate on current and 

potential “leveraging” of these resources. 

Although this review is part of a periodic review of all TAMU doctoral programs, this type of 

review offers an excellent opportunity to identify ways to maintain the current high standards of 

the programs and to learn from review team members’ experiences with similar programs. 

Thank you in advance for playing such and important role in this process.

2 2007 Toxicology External Review 

2. PROGRAM OVERVIEW 

2.A. Texas A&M University 

Texas A&M University was the first public college in Texas established in 1876, and is now 

among the largest institutions of higher learning in the nation - with a student body of about 

44,000. The University offers degrees in more than 150 courses of study and has awarded 

more than 320,000 degrees, including more than 70,000 graduate and professional degrees. It 

consistently ranks among the top five universities in attracting high-achieving National Merit 

Scholars. Its students include men and women of all races, religions, and backgrounds from all 

50 states and more than 100 other countries. Texas A&M is one of the nation’s best-endowed 

universities, a factor that helps it attract and retain top faculty members and provide state-of-theart 

facilities in areas that coincide with its goals and strengths. The university’s endowment 

places it among the top 10 nationally. 

Teaching and research go hand in hand at Texas A&M as it carries out its commitments as a 

land-, sea-, and space-grant institution - one of a select few universities to hold all three federal 

mandates. Its investment in research places it high in rankings by the National Science 

Foundation. The university’s research endeavors are complemented by a strong and growing 

graduate education program. The Look College of Engineering also ranks high in the nation in 

research expenditures. 

Each year, Texas A&M's 2,500 faculty conduct approximately $500 million worth of sponsored 

research projects, assisted by more than 5,000 paid graduate students. Additionally, 

approximately 3,000 undergraduates each year conduct independent research with faculty 

supervision. Research at Texas A&M is about faculty and students driven by the spirit of 

discovery and committed to pushing back the boundaries of knowledge. At the same time, the 

majority of the work is dedicated to solving real-world problems and improving the lives of the 

public we serve. For the past 17 years, the Interdisciplinary Faculty of Toxicology (IFT) has 

played an important role in the teaching, research, service and outreach missions of the 

University in an important area of the biomedical sciences collectively referred to as 

Environmental Health Sciences. 

The major function of the IFT is the administration of graduate programs leading to the Master 

of Science and Doctor of Philosophy degrees in Toxicology, in conformance with the rules of the 

Office of Graduate Studies of TAMU. The IFT provides leadership for activities and functions 

which are critical for the development and growth of a research and training program that is 

nationally recognized in environmental health sciences. 

2.B. Interdisciplinary Faculties 

Interdisciplinary Faculties are relatively recent addition to academic programs at TAMU. They 

have arisen as faculty-derived initiatives designed to capitalize on diverse strengths of individual 

investigators with interests in focused programmatic areas. In their current form, mature 

interdisciplinary faculties documented their ability to maintain a graduate program and have 

been authorized to administer graduate degrees. The earliest interdisciplinary faculty, the 

Interdisciplinary Faculty of Genetics was formally recognized in 1989 although the official origins 

of that faculty began in 1983. The IFT was the second interdisciplinary faculty established in 

1989.


Faculty participation in the IFT is by “membership” rather than as an “academic appointment” as 

all IFT members have primary appointments in academic departments where promotion and 

tenure decisions are made. Consequently, the IFT has no formal responsibility for promotion 

and tenure decisions. However, the IFT Executive Committee has in the past and is currently 

prepared to provide written documentation, at the request of IFT members, of their contributions 

to the program in support of departmental tenure and promotion considerations. 

The Toxicology Graduate Program administered by the IFT provides a comprehensive 

academic and research experience for graduate students interested in pursuing a career in the 

multidisciplinary field of toxicology. The didactic coursework combined with a solid research 

experience in the Toxicology Graduate Program is designed to provide core competencies in 

toxicology and environmental health sciences. While the Core Courses are administratively 

housed in several academic departments, IFT faculty have the academic freedom to ensure that 

the course offerings enable graduate students to obtain outstanding training and research 

opportunities in molecular and cellular toxicology, biochemical and endocrine toxicology, cancer 

causation and prevention, reproductive and developmental toxicology, neurotoxicology, food 

safety and environmental toxicology. 

Unlike departments, interdisciplinary faculties lack a stable funding base, infrastructure, and 

paid support staff beyond the one paid Administrative Assistant. The Chair of the Faculty and 

Executive Committee serve in a voluntary capacity without any additional salary supplement. 

The program depends upon varying degrees of assistance from departments in which faculty 

maintain a primary appointment to assist with administrative office space, basic bookkeeping 

and accounting assistance related to trainee payroll, travel and other fiscal matters. During the 

past four years, there have been changes in the structure and management of the IFT due to 

the pro-active administration of the Office of the Vice President for Research and Graduate 

Studies. This Office, in cooperation with the Council of Participating Deans, identified a 

mechanism for more stable funding for the IFT (2004-2007) that is renewable pending a detailed 

report of academic, research and enrichment activities. The IFT and other interdisciplinary 

faculties all report to the Office of the Vice President for Research, and this new reporting line 

was established to increase the stability of these programs. The Administrative Framework for 

Interdisciplinary Programs was formalized as a University Rule 15.01.99.M7, approved 

December 14, 2006 (Appendix A). This rule sets forth requirements for the establishment of 

interdisciplinary programs including annual reporting and coordination of interdisciplinary 

program efforts with other members of the TAMU System. 

2.C. Development of the IFT and Related Centers and Programs 

Toxicology research and training at TAMU was initiated in 1970 by the Department of Veterinary 

Physiology and Pharmacology and was extensively reorganized in the late 1980s to reflect the 

interdisciplinary nature of the environmental health research and training activities on this 

campus. In 1989, faculty from 6 Colleges and 17 Departments within the University and other 

affiliated State and Federal Laboratories formed the Interdisciplinary Faculty of Toxicology (IFT). 

The new IFT represented a unique model for developing a graduate program that encompasses 

students and faculty from different administrative units. In 1990, the Texas A&M University 

Faculty Senate and the State Coordinating Board for Higher Education approved the request for 

reassigning administrative responsibility for the degree program from the Department of 

Veterinary Physiology and Pharmacology to the Interdisciplinary Faculty of Toxicology. 

Students receive their Toxicology degree administered by the IFT; however, all students receive 

services through the Department of their mentors even though these Departments do not


receive graduate credits for Toxicology students. Students are expected fulfill the academic 

requirements of their home Departments and the IFT. This approach facilitates the recruitment 

of students into the IFT from multiple Departments and Colleges and greatly facilitates the 

development of trainees who not only have a basic understanding of the environmental health 

sciences but also appreciate the skill sets of scientists with different research interests. 

Currently, the IFT involves 45 faculty from 15 Departments, 5 Colleges, 2 affiliated laboratories 

(USDA and Texas Veterinary Medical Diagnostic Laboratory) at TAMU, and from 4 Departments 

and 3 Units of the Texas A&M Health Science Center (TAMHSC). Although TAMU and the 

TAMHSC are independent entities of the Texas A&M System, the structure of the IFT 

accommodates students from both Institutions (Figure 1.). The IFT Executive Committee 

consists of 7 faculty members and one Graduate Student member. This committee provides 

administrative oversight for the activities of the Faculty. 

Council of 

Participating Deans 

Office of the Vice President 

for Research and Graduate 

Studies 

TAMU Colleges 

Agriculture & Life Sciences 

Engineering 

Liberal Arts 

Science 

Veterinary Medicine 

Interdisciplinary 

Faculty of Toxicology 

(IFT) 

Texas A&M Health Science Center 

College of Medicine 

School of Rural Public Health 

Inst. of Biosciences & Technology 

Others 

USDA 

TVM Diagnostic Laboratory 

Participating Departments 

Animal Science 

Biochemistry & Biophysics 

Chemistry 

Civil Engineering 

Entomology 

Environmental & Occupational 

Health 

Molecular & Cellular Medicine 

Neuroscience & Experimental 

Therapeutics 

Nutrition and Food Sciences 

Poultry Science 

Psychology 

Statistics 

Systems Biology & Translational Medicine 

Veterinary Integrative Biosciences 

Veterinary Large Animal Medicine 

Veterinary Pathobiology 

Veterinary Physiology & Pharmacology 

Wildlife & Fisheries Sciences 

Figure 1. Summary of Colleges, Departments and Programs involved in the IFT. 

The IFT, through exceptional initial and ongoing leadership of Dr. Stephen H. Safe and several 

other key faculty, and the research and training activities of IFT members, has established an 

internationally recognized program incorporating Environmental Health Research, Training, and 

Outreach at TAMU. The IFT has served as the TAMU campus model for interdisciplinary 

faculties that develop related programs, centers and a national research and training identity. 

In the following section, the unique contributions of the IFT to environmental health science 

research and training programs at Texas A&M University are summarized.


2.C.1. Toxicology Training Grant: Development of the IFT 

model for interdisciplinary training in Toxicology was critical for 

unifying diverse campus programs in this discipline and was 

important for our first successful NIEHS Toxicology Training 

Grant application prepared by Dr. Stephen H. Safe, and entitled 

“Toxicology of Environment Contaminants.” This training grant 

was initially funded in 1992, has been renewed three times and is 

now in its 15 th year of continuous funding 

(http://www.niehs.nih.gov/dert/training/t32-inst/texasam.htm). It 

serves as a model for many other life sciences initiatives at 

TAMU. The IFT benefits from new and expanding initiatives in the environmental health 

sciences that provide a stimulating and challenging atmosphere for graduate students, 

postdoctoral trainees and faculty. 

This training program is coordinated through the Interdisciplinary Faculty of Toxicology (IFT) 

which has faculty membership from all the major Life Sciences Departments. Pre- and 

postdoctoral trainees also participate in the multiple environmental health science initiatives 

including the Center for Environmental and Rural Health (CERH), Superfund Basic Research 

Program (SBRP), and K-12 programs. All trainees will complete core courses in Toxicology and 

satisfy IFT, Departmental and University academic requirements. Trainees also participate in 

multiple enrichment activities which include: (a) participation in annual research symposia 

sponsored by IFT and CERH; (b) attendance at weekly IFT seminars; (c) participation at both 

regional (Gulf Coast) and national Society of Toxicology meetings; and (d) participation and 

attendance at other local, regional and national scientific conferences. The training program 

provides a challenging research program focused on diverse areas of environmental toxicology 

directed by ten coinvestigators who are members of the IFT. The training program continues to 

focus on recruitment of underrepresented minorities and clinical scientists and provide trainees 

with a challenging academic and research environment that will prepare them for future careers 

in academia, industry and government. 

2.C.2. Superfund Basic Research Program: The Superfund 

Basic Research Program (SBRP, http://sbrp.tamu.edu) Project at 

TAMU, which was organized by Dr. Safe, was originally funded in 

1989 about the same time as the IFT was established. The SBRP 

and has been renewed three times, and is now in its 18 th year of 

continuous funding for this highly interdisciplinary research project. 

The TAMU SBRP has recently cosponsored the Central and Eastern European Conferences on 

Health and the Environment (Prague, Czech Republic, 2004; Bratislava, Slovakia, 2006). 

The major theme of the SBRP at TAMU is to conduct fundamental research to reduce the 

uncertainty associated with risk assessment of complex mixtures, and to improve scientific and 

public confidence in the overall risk assessment process. The program includes toxicological 

studies to define the mechanism(s) of action and dose-response relationships of chemical 

mixtures associated with Superfund sites. These projects are integrated with engineering and 

non-biomedical studies that will examine remedial procedures and estimate exposures due to 

contaminant releases. The chemical exposure and dose-response information will facilitate 

interpretation of data from population studies and relate the incidence of adverse effects in a 

population to levels of contaminant exposure. The TAMU SBRP includes research projects in 

four major areas of research including: 1) Mechanism-based research focused on the effects of 

Superfund-related chemicals on endocrine disruption, genotoxicity and cellular injury; 2) 

Susceptibility and predisposition research to determine if single nucleotide polymorphisms


(SNPs) increase sensitivity to chemical-induced birth defects; 3) Remediation research to 

investigate various methods for the stabilization or detoxification of Superfund contaminants; 

and 4) Exposure and risk assessment research. This research is facilitated by three technical 

support cores and Translational Research, Outreach, Training and Administrative Cores. 

2.C.3. Center for Environmental and Rural Health: A concept 

for a Center for Environmental and Rural Health (CERH, 

http://cerh.tamu.edu) was developed by IFT faculty from several 

disciplines and, in 1998, a new NIEHS Environmental Health 

Science Center of Excellence was awarded to TAMU. Stephen 

Safe (PI and Director) and Kenneth Ramos (Co-PI and Deputy 

Director) provided the initial administrative leadership and Dr. 

Ramos assumed the role of PI and Director in 1999 until he took 

his current position at the University of Louisville in 2003. Dr. 

Safe became Interim Director in April, 2003 and remained in that 

position until July, 2004 when Dr. Philip Mirkes was recruited as 

Director. The CERH, whose membership involves over half of the IFT, was successfully 

renewed in 2002 and in now in its 9 th year of continuous funding. The theme of the Center for 

Environmental and Rural Health (CERH) is to integrate outstanding basic and applied research 

in an effort to reduce negative impacts of environmental hazards on human health. Basic 

research programs are focused on understanding the molecular/cellular mechanisms by which 

environmental toxicants contribute to disease pathogenesis, with particular emphasis upon the 

role of signal transduction pathways. Basic research will be enhanced by the availability of new 

animal models for human disease developed by Center investigators, and will be integrated with 

more applied research activities focusing upon the development of biomarkers of exposure, 

susceptibility, and disease, and the improvement of strategies for disease prevention and 

therapies. Center translational research is focused on two geographically separate but 

integrated research programs involving different rural and underserved populations. One 

ongoing effort involves Hispanic populations on the Texas-Mexico border who are highly 

exposed to environmental toxicants and present with an increased incidence of birth defects, 

cancer, and diabetes/obesity. The second effort focuses upon rural, underserved populations in 

Africa, Azerbaijan, and China who are also exposed to high levels of environmental toxicants 

and are marked by significantly elevated rates of cancer and birth defects. Center translational 

research is facilitated by partnerships that have been developed with various community 

organizations and state, national and international environmental health research and regulatory 

agencies. 

2.C.4. Partnership for Environmental Education and Rural 

Health: The Partnership for Environmental Education and Rural 

Health (PEER, http://peer.tamu.edu) is supported by funding from the 

NIEHS and NSF and was developed as part of the Community 

Outreach and Education Core of CERH to create an engaging model 

for integrating environmental health science into educational 

programs in grades 6-8. Goals are to: 1) integrate environmental 

health materials/issues into multimedia learning curricula tailored for 

rural middle-school students (integrated math, language arts, social 

studies, and science curricula transmitted to public schools via the internet and classroom 

visits); 2) provide professional development programs for teachers (short courses for teams of 

teachers from the same school) that integrate web-based environmental health science 

curricula in order to enhance teachers awareness of environmental health problems and 

solutions; and 3) provide both a human interface and online interaction to establish partnerships


among middle schools and scientists whereby faculty and/or graduate students visit public 

schools personally or online to present environmental health issues that foster learning 

opportunities for inquiry-based scientific research. These activities promote environmental 

health science education and encourage students to pursue careers in the environmental health 

sciences. Aspects of this program can be found in a “PEER Perspectives” report located in 

Appendix B. This program was supplemented with an NSF GK12 grant (“Fellows Integrate 

Science/Math in Rural Middle Schools” NSF No. 0338310 [01 Jan 2004 – 31 Dec 07]) which 

funds graduate teaching fellowships in K-12 education to convey value of research and 

discovery to enrich science, technology, engineering, and mathematics (STEM) to K-12 

students and teachers. The emphasis of this instructional program is on environmental health 

science, and some of the 10 graduate student Fellows funded by this grant are working in 

toxicology laboratories. This NSF GK12 project “Continuing GK12 Fellows Integrate 

Science/Math in Rural Middle Schools” NSF No. 0638738 (01 Feb 07 – 31 Jan 2010) 

emphasizing environmental health science curriculum produced by the NIEHS grant R25 

ES010735 was recently continued for three years. This grant generated local TAMU funds of 

$81,000 to allow institutionalization of the concept of using STEM graduate students as 

environmental health science content resources. An important feature of the PEER website 

(http://peer.tamu.edu) that provides rural community outreach in environmental health science is 

the “Teacher Requested Resources.” This site allows teachers in rural areas to ask scientists 

questions, identify websites of interest, and get activities and lesson plans produced by the 

undergraduate and graduate students of the NSF GK12 program. Members of the Faculty of 

Toxicology serve as content reviewers of these “Teacher Requested Resources” whereby they 

serve the underrepresented, geographically-isolated, and disadvantaged students and teachers 

of Texas and the nation. 

Related projects have been submitted to provide community outreach in environmental health 

science education along with promotion of environmental research and discovery. One is the 

NSF URM proposal entitled “Mentoring Undergraduate Research and Discovery” which employs 

undergraduate students who learn about and conduct research in laboratories of several 

members of the Faculty of Toxicology. Another proposal entitled “Science Promotion in Rural 

Middle Schools” has been submitted to NIH and HHMI which empowers local veterinarians to 

promote environmental health science in their regional public schools. A proposal has been 

submitted to the Harris Foundation by their request to provide 50 underrepresented middle 

school students a two week summer camp to encourage math and environmental health 

science education, motivate youth to stay in school, and foster leadership and citizenship. 

Hence, this is another opportunity for our toxicology faculty and graduates students to provide 

environmental health science community service: in this case, providing academic opportunity 

to disadvantaged and underrepresented but talented middle school students. 

Collectively, the IFT is responsible for numerous 

unique contributions, many of which result from the 

convergence of the NIEHS-funded programs 

including the Toxicology Training Grant, CERH, 

SBRP, and PEER program (Figure 2) that also 

sponsor additional local and regional symposia and 

conferences. 

Figure 2. The IFT is central to multiple 

environmental health science research and training 

programs at TAMU.


These unique programs have greatly: 1) increased the scope of environmental health sciences 

research and faculty interactions at the University; 2) enhanced the quality and diversity of the 

research environment for our trainees; and 3) increased the visibility and prominence of TAMU 

as a leader in environmental health research and training. These are supplemented by an 

established campus-wide Toxicology Seminar series which brings in toxicologists as well as 

collaborators from other Superfund Program Projects and Centers of Excellence, and also by 

regional Gulf Coast Society of Toxicology meetings. Both of these forums provide personal and 

professional development opportunities for graduate and postdoctoral trainees. 

2.C.5. IFT Executive Committee and Chairs 

IFT Executive Committee Membership, 1990-2006 

1990-91 1992 1993 

Murl Bailey Murl Bailey Murl Bailey 

Kirk Brown David Busbee David Busbee 

David Busbee Bruce Dale Bruce Dale 

George Chiou Tim Phillips Larry Johnson 

Bruce Dale Ken Ramos Tim Phillips 

Wayne Ivie Steve Safe (chair) Ken Ramos 

Tim Phillips 

Steve Safe (chair) 

Steve Safe (chair) 

James Way 

1994 1995 1996 

Murl Bailey Murl Bailey (resigned 8/95) Evelyn Castiglioni 

David Busbee Evelyn Castiglioni K.C. Donnelly 

Evelyn Castiglioni Rick Finnell Rick Finnell 

Bruce Dale Larry Johnson Scott McKenzie (student) 

Larry Johnson Tim Phillips Tim Phillips (chair) 

Tim Phillips Weston Porter (student) Ken Ramos 

Weston Porter (student) Ken Ramos (chair) Steve Safe 

Ken Ramos (chair) Steve Safe David Thompson 

Steve Safe 

David Thompson 

David Thompson 

1997 1998 1999 

Evelyn Castiglioni Napoleon Alejandro (student) Napoleon Alejandro (student) 

K.C. Donnelly Bob Burghardt Bob Burghardt 

Rick Finnell Raymond Carroll Raymond Carroll 

Scott McKenzie (student) Evelyn Castiglioni Evelyn Castiglioni 

Tim Phillips (chair) K.C. Donnelly K.C. Donnelly 

Ken Ramos Rick Finnell Tim Phillips 

Steve Safe Tim Phillips Ken Ramos (v. chair) 

David Thompson Ken Ramos (v. chair) Steve Safe (chair) 

Steve Safe (chair)


2000 2001 2002 

Napoleon Alejandro (student) Napoleon Alejandro (student) Bob Burghardt 

Bob Burghardt Bob Burghardt Evelyn Castiglioni 

Raymond Carroll Raymond Carroll Leslie Cizmas (student) 

Evelyn Castiglioni Evelyn Castiglioni K.C. Donnelly 

K.C. Donnelly K.C. Donnelly Alan Parrish 

Tim Phillips Tim Phillips Tim Phillips (chair) 

Ken Ramos (v. chair) Ken Ramos (v. chair) Ken Ramos 

Steve Safe (chair) Steve Safe (chair) Steve Safe (v. chair) 

Yanan Tian 

2003 2004 2005 

Bob Burghardt Bob Burghardt Bob Burghardt (chair) 

Evelyn Castiglioni Evelyn Castiglioni Brian Laffin (student) 

Leslie Cizmas (student) K.C. Donnelly Phil Mirkes 

K.C. Donnelly Alan Parrish Tim Phillips (v. chair) 

Alan Parrish Tim Phillips (chair) Weston Porter 

Tim Phillips (chair) Steve Safe (v. chair) Shashi Ramaiah 

Steve Safe (v. chair) Yanan Tian Steve Safe 

Yanan Tian 

Yanan Tian 

2006 

Bob Burghardt (chair) 

Brian Laffin (student) 

Phil Mirkes 

Tim Phillips (v. chair) 

Weston Porter 

Shashi Ramaiah 

Steve Safe 

Yanan Tian 

2.D. Administrative Structure of the IFT (2002-present) 

The administrative structure of the IFT is comparable to that of other interdisciplinary faculties at 

TAMU. The Chair and Executive Committee report directly to the Vice President for Research 

and Council of Participating Deans who provide partial base support for the IFT. The Chair and 

Executive Committee have primary faculty appointments in one of the participating departments 

and provide uncompensated service to the IFT. Their specific responsibilities are outlined in the 

IFT Bylaws (Appendix C) and briefly these include administrative oversight of the program. 

One, full-time Administrative Assistant reports to the IFT Chair and implements numerous 

aspects of managing a diverse range of duties in support of the trainees and participating faculty 

of the IFT. The specific duties of the Administrative Assistant are enumerated in Appendix D. 

A variety of support services are donated to the IFT by departments in which IFT members have 

primary faculty appointments. Support services include, but are not limited to, provision of office 

space and computer support, accounting, payroll, and travel support. IFT faculty perform the 

teaching and mentoring duties and provide documentation of theses activities to the IFT 

Executive Committee through the Administrative Assistant. Despite this rather modest 

administrative structure, the mission of the IFT is effectively carried out by a highly interactive 

and collegial faculty.


Vice President for Research 

and 

Council of Participating Deans 

IFT Executive Committee 

IFT Administrative Assistant 

Participating 

Departments 

Participating 

Departments 

IFT Faculty 

2.E. Previous Program Review and Changes in the Past Five Years 

2.E.1. Previous Program Review 

In November, 1998, the IFT was reviewed by an external group of five toxicologists from other 

institutions, namely, Dr. James A. Klaunig (University of Indiana), Dr. Margaret O. James 

(University of Florida), Dr. Robert Chapin (National Institute of Environmental Health Sciences), 

Dr. Daniel Acosta (University of Cincinnati), and Dr. Donald Fox (University of Houston). The 

following summary highlights the major headings of the evaluation and a brief statement of the 

findings. 

The unanimous consensus of the External Review Committee is that the IFT program has an 

exceptional toxicology training program. The committee found that the IFT had strong direction 

and leadership and that the administrative structure was effective and provided a democratic 

structure of governance. The faculty were acknowledged for their energy and breadth and, 

through their common research and training activities, a collaborative and synergetic presence. 

Well equipped laboratories and support from extramural and intramural sources were 

considered an asset. The IFT was acknowledged for the instrumental role in securing the 

NIEHS Toxicology Training Grant, Superfund Basic Research Program and Center for 

Environmental and Rural Health. The IFT was able to attract an excellent pool of graduate 

students who demonstrated scientific knowledge and the ability to communicate the status of 

the toxicology program. The graduating students were recognized as exceptional by the 

scientific community. Reviewers regarded enrichment activities as additional strengths of the 

IFT training program. 

The External Review Committee identified 5 weaknesses and offered 6 recommendations:


1. There was no permanent adequate funding base for the administrative core functions and 

full first year funding of student stipends within the IFT. The solicitation of annual 

operational funds detracts from the primary focus on training and research. The lack of first 

year stipends limits choices of mentors. The review committee recommended that the 

university should provide stable and full support of the IFT administrative functions and 

activities including program enrichment (travel and meeting presentations) for students, 

seminars by invited speakers, and the salary for the program assistant. The university 

should provide full funding for all first-year graduate students. 

2) There was the lack of a formal mechanism for faculty input in the hiring/promotion/ 

retention of faculty associated with IFT. IFT faculty do not have control of the content and 

scheduling of core toxicology courses, which constrains their ability to most effectively teach 

students. The review committee recommended provision of faculty input into faculty career 

decisions (recruitment, mentoring, promotion and tenure). 

3) There was not a balanced, comprehensive core course of toxicologic principles and 

effects required of all students in the program. The review committee recommended 

development and requirement for an annual, team taught, core course of Principles of 

Toxicology, which addresses organ system responses and specific classes of toxicants. 

4) Concerns raised by students included advising issues related to course selection and 

laboratory rotations, perceived inequity in student support (tuition, stipend and insurance), 

and difficulties of communicating electronically across colleges and departments. The review 

committee recommended a guaranteed base of student stipend/insurance/tuition support for 

all IFT students as well as the development of a reliable electronic communication system 

for IFT students. 

5) Lack of interactions between relevant toxicology units in the Medical School and 

Veterinary Schools. The review committee recommended encouragement of greater 

participation from the Medical School faculty in IFT. 

Additional recommendations of the review committee included the need for better 

recognition of and credit for faculty contributions to the IFT effort (i.e., teaching, mentoring, 

student committee work, and service) by departmental administrators. Periodic review of the 

IFT to maintain the quality of the program was also recommended. 

The concluding statement of the External Review Committee was: 

"Overall, the External Review Committee considers the IFT to be an outstanding 

program, which has a justly deserved international reputation of excellence." 

2.E.2. Changes in the IFT since the previous review 

Major changes that have taken place since the previous review include: 

1) During the past four years, there has been improvement in the structure and 

management of the IFT due to the pro-active administration of the Office of the Vice 

President for Research and Graduate Studies. As noted above, this Office, in cooperation 

with the Council of Participating Deans, has identified funding for the IFT (2004-2007) which 

is renewable pending a detailed report of our academic, research and enrichment activities.


The IFT and other interdisciplinary faculties all report to the Office of the Vice President for 

Research, and this new reporting line was expected to stabilize these programs. 

2) The Office of the Vice President for Research and Graduate Studies IFT now provides 

the IFT with $40,000 designated for Regents’ Fellowships that support two incoming 

graduate students. 

3) Since 2002, the Administration of the College of Veterinary Medicine and Biomedical 

Sciences included the Director of the CERH as a member of the College’s Executive 

Committee. Through representation on the Executive Committee, the IFT and its related 

programs including the CERH has been provided a mechanism for IFT input in decisions 

that affect the IFT including infrastructure and faculty recruiting. 

4) Based upon recommendations made by the External Review Committee, the IFT 

Graduate Training Curriculum has been revised in order to provide comprehensive core 

courses of toxicologic principles and effects required of all students in the program. These 

core courses include: A) Basic Environmental Toxicology (VIBS/PHEO 610) covering an 

overview of classes of chemicals, organ system responses, and environmental health; B) 

Metabolic and Detoxication Mechanisms (VTPP 673) covering phase I and phase II drug 

metabolizing enzymes and molecular mechanisms of action of diverse drugs, toxins, and 

genotoxins with emphasis on interpretation of experimental data; C) Genetic and Molecular 

Toxicology (VTPP 676) covering molecular mechanisms and adverse effects induced by 

exposure to environmental chemicals and therapeutic drugs; D) Food Toxicology (VIBS 618) 

covering health implications of toxic factors (natural as well as synthetic) in food: their 

source, nature, occurrence, distribution, toxicities, and mechanisms of action; research 

techniques and methodologies applicable to food safety. A fifth course in the toxicology 

sequence is listed as recommended elective and is entitled Chemical Hazards Assessment 

(PHEO/VIBS 605). This course covers chemical and biological methods for testing 

hazardous chemicals and complex mixtures. Collectively, these courses provide a more 

balanced and comprehensive core knowledge base and involving broader participation of 

members of the IFT. 

5) Concerns raised by students related to advising issues for course selection and 

laboratory rotations have only partially been addressed. Course selection issues arose 

because a number of courses in the program are only offered once every other year. This is 

due in part to the size of the yearly pool of new students. At this time, laboratory rotations 

are not being scheduled for many incoming students because of limitations in extramural 

funding to support graduate student stipends. Rather, the Executive Committee currently 

attempts to match incoming students with IFT faculty who indicate that funding is available 

for a new student. 

Other advising issues have been addressed as the result of stable funding for an IFT 

Administrative Assistant. Since 1996, Mrs. Kim Daniel has held this position and has 

provided outstanding management of the IFT, student services for IFT trainees and 

enrichment programs including those supported by the Toxicology Training Grant. She also 

supports linkages of the IFT with the Texas A&M University SBRP Project and the CERH. 

Mrs. Daniel, in consultation with the IFT Chair and Executive Committee, coordinates trainee 

recruitment and laboratory rotations, prepares newsletters and preparation of annual reports 

and status of the program.


With the guidance of two IFT members, she organizes the IFT seminar program to ensure 

that the speaker's schedule involves maximum interactions with graduate 

student/postdoctoral trainees. She also coordinates room scheduling and advertising of the 

seminar program which has been ongoing since 1983. She assists Dr. Porter with 

organization of the annual IFT Graduate Student Forum where graduate students present 

either posters or 15 minute oral presentations of their ongoing and proposed research. The 

IFT and the College of Veterinary Medicine and Biomedical Sciences Graduate Student 

Association also provide funding for all graduate student/postdoctoral trainees to attend a 

national scientific meetings; Mrs. Daniel coordinates the travel in collaboration with 

participating faculty and departmental staff. These enrichment activities are invaluable to 

the trainees who attend a host of national/international symposia including annual meetings 

of the Society of Toxicology, American Association for Cancer Research, Endocrine Society, 

FASEB, Society for the Study of Reproduction, and Keystone symposia. Mrs. Daniel also 

plays an active role in recruiting at local and state recruiting fairs, and she is a member of 

the Society of Toxicology Committee on Diversity Initiatives. 

6) Increased interactions between relevant toxicology units in the Texas A&M Health 

Science Center and Texas A&M University have taken place since the previous review. A 

number of faculty from the newly formed School of Rural Public Health and the Institute of 

Biosciences and Technology play key roles in the Texas A&M CERH and/or SBRP. 

Increased interdisciplinary interactions driven by the IFT have also taken place with other 

units within the Texas A&M University System including faculty from the Colleges of Science 

(Biology and Statistics) and Engineering (Chemical). 

2.F. Budget Information 

2.F.1. Funding Allocations 

During the past fiscal year, FY06, which ran from 9/1/2005 through 8/31/2006, the IFT received 

a total of $95,000 for operating expenses, and $40,000 for fellowships. 

Allocations were received from the Vice President for Research ($60,000), the Office of 

Graduate Studies ($40,000, designated for Regents’ Fellowships), the College of Veterinary 

Medicine and Biomedical Sciences ($20,000), the College of Agriculture and Life Sciences 

($5,000), the College of Science ($5,000), and the Institute of Biosciences and Technology 

($5,000). An additional anticipated allocation from the Texas A&M Health Science Center 

($5,000) was not received. 

For the current fiscal year, FY07, which runs from 9/1/2006 through 8/31/2007, the IFT received 

$60,000 for operating expenses and $40,000 for fellowships by the end of January. As for 

FY06, these allocations were received from the Vice President for Research ($60,000) and the 

Office of Graduate Studies ($40,000 designated for Regents’ Fellowships). Financial 

commitments for FY06 and FY07 were identical, and an additional $40,000 in allocations is 

anticipated. 

2.F.2. Expenditures 

The budgets and expenses for Fiscal Years 2006 and 2007 are detailed below.


FY06 

FY07 

Budget Expenses Budget Expenses * 

Seminars 

Fall and Spring Seminar 

Series $12,000 $11,758 $12,000 $5,671 

Graduate Student Forum $1,000 $1,041 $2,000 $1,781 

Administrative Support 

Salaries $45,000 $46,596 $45,000 $43,211 

Office Expenses $1,000 $1,198 $500 $346 

Graduate Enhancement 

Graduate Recruitment $2,500 $66 $2,500 $0 

Regents' Fellowships $40,000 $26,667 $40,000 $20,000 

Fellowship Tuition/Insurance $8,500 $6,240 $8,000 $5,602 

Graduate Travel Support $18,000 $17,113 $18,000 $2,816 

Graduate Assistantships $12,000 $7,488 $12,000 $0 

* September 2006 - January 2007 only 

$140,000 $118,167 $140,000 $79,426 

For FY06, most of the expense categories were less than the budgeted amount. Expenses for 

the first five months of FY07 includes encumbrances for salaries and stipends, but funds to be 

used for other purposes are not yet encumbered. 

Seminars: The Toxicology Seminar Series has been held each fall and spring semester since 

1983. Many faculty and also postdoctoral and graduate trainees recruit speakers for the series. 

For the 2005-2006 academic year, the IFT hosted 22 speakers (4 local, 6 state, and 12 

national), and the 2006-2007 academic year will host an additional 22 speakers (4 local, 2 state, 

15 national and one international). Travel expenses and an honorarium are provided for each 

speaker outside of TAMU. The graduate and postdoctoral trainees are encouraged to interact 

with the speakers, and regularly do so through research discussions and by dining with them. A 

complete listing of the IFT Seminar Series from 1999 to present is included in Appendix E. 

The Toxicology Graduate Student Forum is held annually, and features the students’ 

presentation of their research or research plan to their faculty and peers. Each student who has 

been in the program for one or more years is required to give either an oral or poster 

presentation. Awards are given for the top presentations. 

Administrative Support: The salaries supported by the IFT include those of the Program 

Assistant (100% effort in FY06, 75% effort in FY07), the Business Coordinator (20% effort for 

both FY06 and FY07) and an undergraduate office assistant. Office expenses vary depending 

on the need to purchase computer hardware and software. 

Graduate Enhancement: Graduate student recruiting in recent years has been conducted in 

conjunction with other travel, thus minimizing expense in that category. The IFT has brought 

fewer students to TAMU on recruiting visits, and graduate admissions have declined as well due 

to concerns about funding students for the duration of their graduate careers. The Regents’ 

Fellowship funds (for two first year students at $20,000 per student) are available for use,


however these funds only support stipends, and supplemental funds are required from the IFT 

for tuition and health insurance for these students. These costs increase substantially each 

year. 

The IFT strongly supports trainee attendance and participation at national and regional 

meetings. All students are offered $750 in travel support to attend a national meeting, and the 

IFT sponsors the travel for all students who attend regional meetings. Most of this travel occurs 

in the spring and summer, so these funds are typically spent late in the fiscal year. In FY06, a 

total of 21 trainees received support to attend national meetings (Society of Toxicology, Society 

of Environmental Toxicology and Chemistry, American Association for Cancer Research, 

Teratology Society, Endocrine Society and Keystone Conferences), while 12 attended the Gulf 

Coast Chapter- Society of Toxicology meeting. 

2.G. 

Evaluation and Needs 

Overall, the IFT is a highly collegial interdisciplinary faculty with a solid breadth of expertise and 

research funding base. Faculty participation in the IFT comes with the commitment to 

administration of graduate programs through development and growth of a nationally 

recognized research and training program in Toxicology. The IFT has an administrative 

structure that facilitates communication with the faculty and administration of the program and 

that has been effective in attracting an excellent pool of graduate students and postdoctoral 

fellows. The IFT has continued to serve as a major catalyst for a number of interdisciplinary 

collaborations that include the Texas A&M University Superfund Basic Research Program 

Project, the Center for Environmental and Rural Health, the Toxicology Training Grant, and 

Partnership for Environmental Education and Rural Health program. Based on the collegial 

nature of the IFT and their interdisciplinary accomplishments, the IFT is recognized as a model 

for other Interdisciplinary Faculties on the Texas A&M University campus. There is a need to 

foster and support the IFT and other interdisciplinary faculties if the university is to reach its goal 

articulated in the Vision 2020 long range planning document (Section 3.A.). 

Recent changes in the structure and management of the IFT have included a mechanism for 

more independent status from individual departments in which IFT faculty members maintain 

their primary academic appointment. This change in administrative structure, which was 

formalized in The Administrative Framework for Interdisciplinary Programs and was formalized 

as a University Rule 15.01.99.M7, approved December 14, 2006 (Appendix A) was intended to 

provide more stable funding for the IFT involving base support from the Office of the Vice 

President for Research and Graduate Studies and the Council of Participating Deans which is 

renewable pending a detailed report of our academic, research and enrichment activities. The 

IFT and other interdisciplinary faculties all report to the Office of the Vice President for 

Research, and this new reporting line was expected to increase the stability of these programs. 

However, while the mechanism for identifying base support should increase stability, the 

appropriation of funds usually takes place sporadically throughout the fiscal year and, during the 

past year for example, one of the Participating Deans failed to fulfill the financial commitment to 

supporting the IFT. This instability in funding compromises long range planning. There is a 

pressing need to identify a mechanism for predictable and stable base funding. In addition, due 

to contracting budgets on extramural grants, tuition assistance for trainees and stipends for 

entering Toxicology students is needed to maintain the vitality of the Toxicology training 

program. Further evaluation and discussion of needs is presented in Section 6, Strengths and 

Weakness of the IFT.


3. VISION AND GOALS 

3.A. Vision 2020 

In 1997, Texas A&M embarked upon a comprehensive evaluation and planning program with 

the aim of securing recognition as a consensus "Top 10" public university by the year 2020 

under the direction of then-President, Dr. Ray Bowen. The program known as “Vision 2020 was 

intended to build upon Texas A&M's tradition of excellence, while identifying areas requiring 

improvement and recommending necessary action, without sacrificing the core values upon 

which the university is solidly founded or its proud and unique heritage. The report, Vision 

2020: Creating a Culture of Excellence, sets forth individual recommendations categorized into 

12 "imperatives" relating to all aspects of Texas A&M and its relationships with students, faculty, 

staff, the community and the state, nation and world it proudly serves. 

The 12 “imperatives” include: 

1. Elevate Our Faculty and Their Teaching, Research, and Scholarship 

2. Strengthen Our Graduate Programs 

3. Enhance the Undergraduate Academic Experience 

4. Build the Letters, Arts, and Sciences Core 

5. Build on the Tradition of Professional Education 

6. Diversify and Globalize the A&M Community 

7. Increase Access to Intellectual Resources 

8. Enrich Our Campus 

9. Build Community and Metropolitan Connections 

10. Demand Enlightened Governance and Leadership 

11. Attain Resource Parity with the Best Public Universities 

12. Meet Our Commitment to Texas 

Former TAMU President Robert Gates who served from August 1, 2002 through December 18, 

2006 when he was sworn in as the 22 nd Secretary of Defense, embraced Vision 2020 and 

elected to focus initially on four areas embedded in the original imperatives, plus one new 

imperative: 

• Elevate the faculty (Imperative 1) 

• Improve graduate and undergraduate programs (Imperatives 2 and 3) 

• Diversity and globalization (Imperative 6) 

• Improve space (New Imperative 13) 

In association with the planning process initiated by Vision 2020 and planning processes 

incorporated into both the Life Sciences Task Force at Texas A&M University and Signature 

Programs of the College of Veterinary Medicine and Biomedical Sciences, the IFT has 

developed the following with regard to our statement of purpose and goals: 

3.B. Mission of the IFT 

The IFT has as its primary mission the training of Ph.D. candidates in Toxicology. To do this, 

our faculty provide outstanding research opportunities in molecular and cellular toxicology, 

biochemical and endocrine toxicology, cancer causation and prevention, reproductive and 

developmental toxicology, neurotoxicology, food safety and environmental toxicology.


The IFT aims to foster interdisciplinary research and teaching, and to help prepare graduate 

students as future leaders in research and development, teaching, applied science, policy 

making, and public service through careers in academia, industry and government. 

3.C. Vision 

The IFT has the vision of providing students with diverse and expert toxicological training. The 

curriculum has been developed to provide broad balanced, comprehensive training in 

toxicologic principles and effects. The individualized research training experience is directed 

toward providing the educational and research experience expected of scholarly professionals 

in Toxicology. 

3.D. Strategic Plan 

3.D.1. Goals 

The strategy to accomplish the mission of the IFT is centered on 4 main goals: 

1. Advance the science of toxicology by securing extramurally funded grants to carry out 

fundamental research in molecular and cellular toxicology, biochemical and endocrine 

toxicology, cancer causation and prevention, reproductive and developmental toxicology, 

neurotoxicology, food safety and environmental toxicology. Particular emphasis is currently 

being placed on environmental toxicology. 

2. Recruit high quality graduate students and postdoctoral fellows and provide outstanding 

training to the next generation of toxicologists. 

3. Foster an appreciation of, and create opportunities for interdisciplinary research efforts in 

the interdisciplinary field of toxicology in order to enhance human, animal and environmental 

health. 

4. Gain greater stability in the administrative structure and base funding for the IFT. 

3.D.2. Action Plans 

Plans to achieve the goal of advancing the science of toxicology by securing extramurally 

funded grants include: 

1. Prepare competing renewals of CERH, SBRP, Toxicology Training Grant, and outreach 

grants on schedule. Members of the IFT Executive Committee provide leadership roles in 

preparing each of these proposals focused on environmental health sciences. The 

Executive Committee will encourage submission of individual investigator grants in the area 

of environmental health sciences, as individual investigator grants are necessary to provide 

research identity and research funding base to justify these interdisciplinary grants. 

2. Enhance the IFT by recruiting high caliber toxicologists/environmental health scientists. 

Former TAMU President Robert Gates initiated a faculty reinvestment program with a goal 

of adding 447 new faculty positions by 2008. As of September 1, 2005, 234 of these 

positions had been created and filled. Both the Life Sciences Task Force at Texas A&M 

University and Signature Programs of the College of Veterinary Medicine and Biomedical 

Sciences have identified environmental medicine/toxicology as an area of research strength


to build upon. The Texas A&M University CERH has been promised two new faculty 

positions to recruit new environmental health scientists into the Center. IFT members are 

already in key positions that will determine and influence faculty recruitment. The College of 

Veterinary Medicine and Biomedical Sciences Signature program has one remaining 

Signature Program position which has been allocated to the Department of Veterinary 

Physiology and Pharmacology. 

Plans to achieve the goal of recruiting high quality graduate students and postdoctoral fellows 

and provide outstanding training for the next generation of toxicologists include: 

1. Maintain updated websites that identify training opportunities in toxicology/environmental 

health sciences. The IFT (http://toxicology.tamu.edu/home.htm),Toxicology Training Grant 

(http://www.niehs.nih.gov/dert/training/t32-inst/texasam.htm), CERH (http://cerh.tamu.edu), 

SBRP (http://sbrp.tamu.edu) and PEER program (http://peer.tamu.edu) websites provide a 

window to the world, providing information of interest to potential graduate and postdoctoral 

students. We will continue to ensure that potential trainees are made aware of training 

opportunities sponsored by the IFT. 

2. Recruit prospective students throughout the year through attendance at regional and 

national meeting attendance, visits to other institutions and by sending materials in response 

to all people who express interest through our website or e-mail. Many students are 

recruited directly by their reputation and contact with an individual faculty member. The 

above referenced websites and informational brochure have been positive recruiting tools. 

3. Continue efforts on diversity in recruiting. The IFT Executive Committee will address 

diversity in recruiting through the admissions process of new trainees to the program. 

Further, the IFT Administrative Assistant, will continue to be supported in her participation in 

Society of Toxicology education programs and as a member of the SOT Committee on 

Diversity Initiatives. 

4. Continue to enrich the graduate education and training program by providing 

opportunities for leadership development and participation in extramural professional 

activities. 

Plans to achieve the goal of fostering an appreciation of, and create opportunities for 

interdisciplinary research efforts in toxicology include: 

1. Promote collaborations among members of the IFT and between IFT and other units and 

individuals. We will continue to exploit the organizational structure of the Research and 

Facility Cores of the Texas A&M University CERH and SBRP to promote collaborations 

between members of the IFT and other campus units with interests in environmental health 

research. 

2. Provide IFT members with opportunities for professional development through active 

participation in the leadership of the Faculty. 

3. Enhance communication and interactions among and between faculty and graduate 

students. 

Plans to achieve the goal of gaining greater stability in the administrative structure and base 

funding for the IFT.


1. Maintain high standards in meeting the first three goals of advancing the science of 

toxicology, recruiting high quality trainees, and promoting interdisciplinary research in 

toxicology. 

2. Document the accomplishments and progress of the IFT on an annual basis thorough the 

IFT Annual Report. (The Annual Report of the IFT for January 1, 2005 through April 30, 

2006 [excluding faculty CVs and the IFT Recruiting Brochure] is included in Appendix F. 

and provides a “snap shot” of the most recent activities of the IFT submitted in support of a 

request for continued IFT base funding). 

3. Meet with administrators in the Office of the Vice President for Research to review IFT 

accomplishments annually and justify the need for predictable base funding that includes 

tuition assistance for trainees and increased administrative stability. 

3.D.3. External Factors 

Major external factors that could affect these goals are the instability of programmatic funding 

for the IFT and the increasingly difficult challenge of securing extramural funding for research 

and training programs. The first concern can be addressed directly with Texas A&M University 

administration. The second funding issue is far more complex and aspects of current funding 

issues that highlight the latter concern are emphasized in a recent book, “Bridges to 

Independence: Fostering the Independence of New Investigators in Biomedical Research,” by 

the Committee on Bridges to Independence: Identifying Opportunities for and Challenges to 

Fostering the Independence of Young Investigators in the Life Sciences, National Research 

Council (2005) published by the National Academies Press. In this report, it is noted that the 

age at which scientific investigators receive their first research grant from the National Institutes 

of Health (NIH) has been increasing in recent decades. It is anticipated that a similar situation 

exists in other federal and private funding agencies. Further, the number and percentage of 

grants awarded to younger researchers has been decreasing. As of 2002, the median age at 

which Ph.D. researchers receive their first R01 research grant was 42. Moreover, the 

percentage and absolute number of awards made to new investigators, regardless of age, has 

declined over the last several years, with new investigators receiving less than 4 percent of NIH 

research awards made in 2002. In addition, declining budgets of funded grants is placing 

increasing pressures on mentors to provide graduate stipends and tuition assistance. This has 

resulted in reduced numbers of trainees that can be supported on an individual grant. 

Consequently, there are growing concerns that funding for development of the next generation 

of investigators in general, and toxicologists in particular, is increasingly difficult to obtain. The 

significant lag time from completing a training program to independence as an investigator runs 

the risk of discouraging promising young scientists from pursuing careers in biomedical 

research as they see greater opportunities for independence in other sectors. Both established 

and young individual investigators in the IFT as well as groups of established investigators 

seeking to sustain program project, center and training grants are working to overcome these 

challenges and to further develop an outstanding training program in Toxicology. 

3.E. Connection to the Vision, Goals, Mission, and Objectives of the Texas A&M 

University Vision 2020 

The IFT is committed to contributing to each of the Vision 2020 imperatives that it is in a position 

to influence. Imperatives 1. (Elevate Our Faculty and Their Teaching, Research, and 

Scholarship), 2 (Strengthen Our Graduate Programs), and 12 (Meet Our Commitment to Texas)


are all integrated into our strategic plan. Imperative 9 (Build Community and Metropolitan 

Connections) is an essential element of interdisciplinary research initiatives and outreach 

activities in the Texas A&M University SBRP and Center for Environmental and Rural Health 

programs. The IFT Executive Committee is acutely aware of the need to diversify and globalize 

the A&M Community (Imperative 6) and attempts to address this issue through the admissions 

process of new trainees to the program. Further, minority recruitment is a major priority of the 

Toxicology Program at Texas A&M University. Mrs. Daniel participates in the Society of 

Toxicology education programs and is a member of SOT and its Committee on Diversity 

Initiatives. Since 2000, she has assisted with the Undergraduate Education Program at the 

national meetings which include a large minority contingent. The Toxicology Program receives 

funding from both a MARC grant (which focuses on underrepresented groups in the sciences) 

and the USEPA (for recruiting from institutions of higher education that receive less than 15 

million dollars in annual research funding). She actively encourages these students and some 

postdoctoral fellows to consider the Texas A&M University toxicology training program. She also 

has participated in regional recruiting efforts at the "Texas Swing" graduate recruiting fair and at 

the Houston Livestock Show.


4. THE GRADUATE PROGRAM 

4.A. Application Process 

Graduate applicants to TAMU are required to submit an application, transcripts, standardized 

test scores, letters of recommendation and a personal essay. Materials are submitted to the 

TAMU Graduate Admissions Office which evaluates and authenticates the credentials and 

provides the information to the IFT and other academic units in a standard format. The 

application materials are scanned and also entered into a secure database with both formats 

available to the IFT administrative assistant. The administrative assistant is responsible for 

organizing and analyzing the applicant materials and presenting them to the IFT Executive 

Committee who makes admissions decisions. 

4.B. Assistantship Funding 

Texas A&M University offers three types of graduate assistantships—teaching, non-teaching, 

and research. Teaching assistantships are available through departments, as most of the 

interdisciplinary faculties, including the IFT do not have teaching assistantships. Faculty 

members are sometimes able to secure a teaching assistantship for a student, but this is not 

prevalent in the IFT. Non-teaching assistantships are also available through departments, 

however, this generally does not apply to toxicology graduate students since the IFT does not 

have these stipends. Research assistantships funded by individual extramural grants is the 

most common form of compensation for toxicology graduate students. 

Fellowships are the other source of graduate trainee compensation. The IFT receives annual 

funding from the TAMU Office of Graduate Studies for two $20,000 University Regents’ 

Fellowships which are reserved for deserving first-year students . Other highly competitive 

fellowships offered through the Office of Graduate Studies are the Graduate Merit Fellowship 

and the Diversity Fellowship. The NIEHS Toxicology Training Grant provides an additional six 

predoctoral and two postdoctoral fellowships. There is a need for additional assistantships for 

incoming toxicology graduate students to support their first year in the program. 

4.C. Degree Requirements and Coursework 

Admission into the toxicology program requires the successful completion of courses in 

advanced biology and/or chemistry or their equivalents. The completion of a Thesis/Dissertation 

is required for both the M.S. and Ph.D. degrees in toxicology. The M.S. program requires 

approximately 36 hours of post-baccalaureate training and the Ph.D. program requires 96 

hours. A minimum of 64 hours is required on the degree plan for Ph.D. students who have 

completed a M.S. or a D.V.M. or M.D. at a U.S. institution. Core course requirements are 

adjusted for these students on a case by case basis, taking into consideration previous course 

work. The Ph.D. program is more flexible because it is based upon each student’s previous 

training and interests. The M.S. program is more restrictive because there are, by university 

regulations, a specified number of hours of required course work. 

It is strongly recommended that all students in the Ph.D. program complete the core courses 

listed below or their equivalents. Degree plans for individual students vary depending on the 

student's background and research focus. Doctoral students normally complete 36 hours of 

coursework and 60 hours of research credit. The toxicology program emphasizes research as


most students are placed in laboratories during their first semester and continue to conduct 

research while they complete 2-3 courses per semester. 

4.C.1. Core Courses 

Course Full Course Name Credit/Schedule Course Description 

BICH 603 General Biochemistry I 3 credits, offered 

each Fall 

semester 

The biochemical properties of 

macromolecules found in living 

matter; proteins, enzymes, and 

STAT 651 Statistics in Research I 3 credits, offered 

each semester 

VIBS 618 Food Toxicology 3 credits, offered 

most Spring 

semesters 

VIBS 670 

Basic Environmental 


3 credits, offered 

Fall semester 

odd years 

VMID 686 Scientific Ethics 1 credit, offered 

Spring semester 

of even years 

VTPP 673 

VTPP 676 

Metabolic & 

Detoxication 

Mechanisms 

Genetic & Molecular 



Fall semester of 

even years 



of even years 

VTPP 681 Toxicology Seminar 1 credit, offered 

each Fall and 


nucleic acids. 

A non-calculus exposition of the 

concepts, methods and usage of 

statistical data analysis. T-tests, 

analysis of variance and linear 

regression. 

The study of food additives, chemical 

and microbial contaminants, and 

naturally occurring toxins associated 

with foods. 

Introduction to general principles of 

toxicology; test methods, target 

organs and risk. 

Overview of ethical issues 

encountered by toxicologists in 

research, resources, interactions 

with public, and application of 

findings. 

Fate of foreign compounds; their 

inhibitory and antagonistic action 

toward normal metabolic processes 

of the animal body. 

Mechanisms of toxicant-induced 

target organ toxicity with emphasis 

on molecular control of mammalian 

and cell growth differentiation. 

Review and discussion of current 

scientific work in toxicology and 

related subjects. 

4.C.2. Elective Courses 

Toxicology electives are selected from advanced courses which provide additional expertise in 

specialized areas within the sub-disciplines of cellular and molecular toxicology, reproductive 

and neurotoxicology, and environmental toxicology and food safety. 

Electives may be selected from, but are not limited to the following courses:


Course 

Course Name, Credit Hours 

BICH 604 

General Biochemistry II, 3 credits 

BICH 631 Molecular Genetics, 3 credits (cross listed as GENE 631) 

BICH 654 

Structural Biochemistry, 3 credits 

BICH 662 

Eukaryotic Transcription, 1 credit 

BIOL 681 

Seminar, 1 credit 

CHEM 601 

Analytical Chemistry I, 3 credits 

CHEM 602 

Analytical Chemistry II, 3 credits 

CVEN 609 

Environmental Control of Oil & Hazardous Materials, 3 credits 

CVEN 682 

Environmental Remediation of Contaminated Sites, 3 credits 

ENTO 619 

Insect Toxicology, 4 credits 

FSTC 606 

Microbiology of Foods, 3 credits 

MSCI 610* 

Pathogenesis of Human Disease, 3 credits 

NUTR 641 

Nutritional Biochemistry, 3 credits 

PHEO 600* 

Principles of Occupational and Environmental Health, 3 credits 

PHEO 611* 

Occupational Epidemiology, 3 credits 

PHEO 650* 

Risk Assessment I, 3 credits 

STAT 652 

Statistics in Research II, 3 credits 

TAMU 699** 

Basic Concepts of Tumor Biol. 3 credits 

TAMU 699** 

Mechanisms of Carcinogenesis, 3 credits 

VIBS 602 

Histology, 4 credits 

VIBS 603 

Neuroanatomy, 4 credits 

VIBS 605 

Chemical Hazard Assessment, 3 credits 

VIBS 607 

Applied Epidemiology, 4 credits 

VIBS 614 

Biodegradation and Bioremediation, 3 credits 

VIBS 617 

Advanced Cell Biology, 1-5 credits 

VIBS 619 

Food Toxicology II, 3 credits 

VTMI 649 

Immunology, 3 credits 

VTPP 653 

Endocrinology, 3 credits 

VTPP 654 

Molecular Endocrinology, 3 credits 

VTPP 665 

Pharmacology, 4 credits 

WFSC 689 

Special Topics in Wildlife Ecotoxicology, 2 credits 

Highly recommended courses shown in bold 

*Texas A&M Health Science Center course, requires co-enrollment 

**University of Texas courses, requires special permission to enroll 

4.C.3. Enrichment Activities 

In addition to formal coursework, the IFT supports diverse academic, research and enrichment 

programs (Figure 3). The goal of these programs is to promote and sustain collegiality among 

faculty and trainees as well as a high level of professionalism expected of scientists specializing 

in the field of toxicology. These are also integral components of the NIEHS pre- and postdoctoral 

training programs and offer both specialized training in focal areas of research as well 

as exposure to the diverse sub-disciplines encompassing toxicology and environmental health 

research in the U.S. and internationally in Africa, Azerbaijan, and China.


Figure 3. Diverse academic, research and enrichment programs are linked to and supported by 

the IFT. 

In addition to the compulsory academic requirements, the IFT in collaboration with the CERH 

and participating Departments/Colleges sponsors a host of research enrichment activities. The 

philosophy of the IFT has been to encourage and financially support enrichment activities, and 

over 50% of our annual budget is used to bring in seminar speakers and to subsidize student 

travel to the annual Gulf Coast Society of Toxicology (SOT), the national SOT, and other 

meetings. The importance of active student participation in scientific meetings is illustrated by 

the following partial summary of various conferences/symposia attended by our Toxicology 

graduate students and trainees over the past four years. (Refer to Appendix G for a more 

detailed summary of conference attendance.) 

Texas A&M University Scientific Meetings 

1. IFT annual Graduate Student Forum (oral/poster presentations and awards) 

2. Toxicology Seminar Series (weekly invited seminar speakers sponsored by IFT; all IFT 

trainees are expected to attend) (See Appendix E for a complete listing of the seminar 

series since 1998). 

3. College of Veterinary Medicine and Biomedical Sciences Graduate Student Association 

Symposium (poster competition, invited speakers, and awards) 

4. TAMU Student Research Week (invited speakers, poster presentations and awards) 

5. CERH Annual Research Symposium (poster competition and awards) 

6. Department of Biochemistry and Biophysics Graduate Student Presentations (oral 

presentations and awards)


Regional Meetings 

1. Gulf Coast Chapter SOT Annual Meeting (oral/poster presentations and awards) 

2. Texas Forum on Female Reproduction (oral/poster presentations) 

3. Lost Pines Meeting (Cell and Molecular Biology) 

4. M.D. Anderson Annual Symposium on Fundamental Cancer Research and specialized 

meetings (poster presentations) 

National Meetings 

1. SOT Annual Meeting (oral/poster presentations; the majority of IFT students attend with 

subsidized travel) 

2. Other meetings attended by graduate students: Annual meetings of the American 

Association for Cancer Research, FASEB, American Chemical Society, American Society 

for Investigative Pathology, Endocrine Society, International Conference on Dioxins and 

Related Compounds, Keystone Conferences (several), Gordon Conferences (several), 

Society of Neuroscience, Society for Environmental Toxicology and Chemistry, Society for 

the Study of Reproduction, Experimental Biology, American Society of Human Genetics, 

Teratology Society, Conference on Hazardous Waste Research, Superfund Annual Meeting. 

Trainee attendance at these conferences is partially funded by the IFT, with other support from 

individual research grants, the SBRP Project, or travel grants provided by the College of 

Veterinary Medicine and Biomedical Sciences Graduate Student Association, the Office of 

Graduate Studies, and the Department of Biochemistry and Biophysics. These enrichment 

activities are an integral part of Toxicology training at Texas A&M University and ensure that our 

graduates have expertise in presenting their research and in interacting with colleagues and 

peers. 

4.D. Students 

4.D.1. Current Student Profile (Fall 2006) 

As of the Fall Semester, 2006 there are 30 students enrolled in the Toxicology graduate 

program consisting of 27 doctoral students and 3 masters students who are distributed within 4 

departments (Veterinary Integrative Biosciences, Veterinary Physiology & Pharmacology, 

Veterinary Pathobiology, 

and Biochemistry & 

Biophysics) in two Colleges 

(Veterinary Medicine and 

Agriculture and Life 

Sciences) Figure 4. 

BCBP 

2 Students, 

7% 

VTPB 

1 Student, 

3% 

VTPP 

11 Students, 

37% 

Figure 4. Toxicology 

student distribution by 

department. 

VIBS 

16 Students, 

53%


The student profile with respect to gender and ethnicity is summarized in Table 1. Entry 

qualifications and performance in the program for current students is summarized in Table 2. 

Table 1. Fall 2006 Student Profile – Gender and Ethnicity 

Domestic - Caucasian Domestic - Non-Caucasian International Total 

Female Male Female Male Female Male 

PhD 9 4 0 2 10 2 27 

MS 0 1 0 0 1 1 3 

Total 9 5 0 2 11 3 30 

Table 2. Fall 2006 Student Profile -- Qualification and Performance 

Verbal 

GRE 

Quant 

GRE 

Total 

GRE 

Incoming 

GPR 

Current 

GPR 

All students 524 691 1215 3.32 3.78 

Domestic students 559 684 1243 3.46 3.83 

International students 493 698 1191 3.20 3.73 

4.D.2. Applicant Profile, 1998-2006 

Between the academic years of 1998 and 2006, the average number of applicants per year to 

the Toxicology Graduate Program has been 36 per year with an average of 9 students (25%) 

accepted per year. GRE scores and average GPR of applicants, accepted and matriculated 

students are summarized in Table 3. 

Table 3. Toxicology Graduate Applicant Summary 1998-2006 

Academic Total Applicants Accepted Applicants Matriculated 

Year Number 

Ave. 

GPR 

Ave. 

GRE Number 

Ave. 

GPR 

Ave. 

GRE Number 

Ave. 

GPR 

Ave. 

GRE 

1998-99 32 3.51 1236 12 3.50 1265 6 3.49 1332 

1999-00 33 3.43 1212 8 3.40 1234 5 3.30 1174 

2000-01 30 3.51 1194 9 3.62 1209 7 3.65 1199 

2001-02 45 3.21 1199 16 3.45 1168 11 3.52 1152 

2002-03 45 3.47 1245 14 3.21 1199 11 3.18 1173 

2003-04 38 3.42 1234 5 3.62 1214 4 3.65 1243 

2004-05 34 3.28 1200 6 3.33 1202 5 3.34 1180 

2005-06 42 3.26 1142 8 3.33 1175 6 3.22 1165 

Fall 2006 22 3.33 1069 3 3.69 1047 3 3.69 1047 

Averages 36 3.38 1192 9 3.46 1190 6 3.45 1185 

Totals 321 81 58


The retention rate of the new students in the past 8 years is 83%. Of the ten students who left 

the program, four transferred to doctoral programs in other universities (three of them with 

faculty member mentors who departed), three transferred to other degree programs at TAMU, 

and three left to pursue jobs. 

4.D.3. Former students, 1998-2006 

A listing of trainees who have completed course requirements and earned graduate degrees 

from 1998-2004 are listed in Table 4 which summarized degree awarded, date, gender and 

ethnicity, as well as current position. Additional information related to gender and ethnicity of 

the same group of former students is summarized in Table 5. 

Table 4. Toxicology Graduates, 1998-2006 

Graduate 

Date 

Gender & 

Ethnicity* 

Current Position 

Master of Science 

Dana B. Walker 1998C F, C 

Toxicolopathologist, Wyeth Ayerst Research Laboratories, 

Chazy, NY 

Annamarie Bokelman 1999A F, C 

Lecturer, School of Rural Public Health, Texas A&M Health 

Science Center, College Station, TX 

William Scott Wilkie 2002B M, C 

Doctoral student, Pharmaceutical Sciences, Univ. of 

Connecticut, Storrs, CT 

Cristi L. Gomez 2002C F, H Toxicologist, Mary Kay Cosmetics Corporation, Dallas, TX 

Nesrin Serpedin 2003C F, I 

Preparing for medical board exams and applying for residency 

programs, College Station, TX 

Megan A. Sitzlar 2005C F, C Nashville, TN 

Qiulin Tan 2005C M, I Working with a biotechnology company in Dallas, TX 

Doctor of Philosophy 

Sammy K. Frazier 1999A M, C Fredericksburg, TX 

Timothy S. Kalafut 1999A M, C US Army Criminal Investigation Laboratory, Forest Park, GA 

Francis C. Lau 1999A M, A 

Postdoc. Fellow, Human Nutrition Research Center on Aging, 

Tufts University, Boston, MA 

Renqin Duan 1999B M, I 

Postdoc. Fellow, Mammary Biology and Tumorigenesis 

Laboratory, National Cancer Institute, Bethesda, MD 

Kavita Ramamoorthy 1999B F, I Attorney, Smart and Biggar Law Firm, Toronto, ON, Canada 

I-Chen Chen 1999C F, I Research Scientist, Alpha BioLaboratory, Inc, Sunnyvale, CA 

Nancy R. Bordelon 2000A F, C Senior Toxicologist, Alcon USA, Fort Worth, TX 

Yun-Houng Chen 2000A M, I 

Research Scientist, Hematopathology, University of Texas-M. 

D. Anderson Cancer Center, Houston, TX 

Mona S. Gupta 2000A F, I Senior Scientist, Afton Chemical Corporation, Richmond, VA 

Kim Poe Lu 2000A F, I College Station, TX 

Gulan Sun 2000A F, I Research Scientist, Ambion, Inc., Austin, TX 

James Kevin Kerzee 2000B M, C Director, Research Support Services, Harlan, Indianapolis, IN 

Shawna L. Lemke 2000B F, C Senior Scientist, Monsanto Company, St. Louis, MO 

Andrew J. McDougal 2000B M, C 

Toxicologist, Office of Food Safety, Food & Drug 

Komkrich Pimpukdee 2000B M, I 

Administration, College Park, MD 

Chair, Vet. Public Health, College of Vet. Medicine, Khon Kaen 

Univ., Thailand 

William R. Reeves 2000B M, C Consultant, Tetra Tech, St. Louis, MO 

Katherine R. Springman 2000C F, H Brownsville, TX 

Erika J. Straka 2000C F, C Nashotah, WI 

Napoleon F. Alejandro 2001A M, H 

Senior Scientist, Toxicology & Safety Assessment, Boehringer 

Ingleheim Pharmaceuticals, Inc., Ridgefield, CT 

Sean E. Ottinger 2001A M, C Toxicologist, Bristol-Myers Squibb, Evansville, IN


Wen Xie 2001A F, I 

Preparing for medical board exams and applying for residency 

programs, Bethesda, MD 

Emely Castro-Rivera 2001B F, H 

Hamon Center for Therapeutic Oncology Research, U.T. 

Southwestern Medical Center, Dallas, TX 

Thu A. Nguyen 2001B F, A 

Asst. Professor, Diagnostic Medicine Pathobiology, Kansas 

State Univ., Manhattan, KS 

Taehyeon M. Cho 2001C M, A 

Postdoc. Research Assoc., Environmental & Molecular 

Toxicology, North Carolina State Univ., Raleigh, NC 

Shannon S. Garcia 2001C F, H Consultant, Tetra Tech, Dallas, TX 

Chunhua Qin 2001C M, I Research Scientist, Merck Research Labs., West Point, PA 

Charles L. Ake 2002A M, I Environmental Consultant, Spring, TX 

M. Hadi Falahatpisheh 2002A M, A Senior Toxicologist, Southern Research Inst., Birmingham AL 

Roger Shane Gold 2002A M, C Asst. Professor of Biology, Brigham Young Univ., Oahu, HI 

Henry J. Huebner 2002A M, C 

Senior Academic Advisor, Biomedical Science, Texas A&M 

University, College Station, TX 

Matthew A. Stoner 2002A M, C 

Asst. Professor, College of Pharmacy, University of Rhode 

Island, Kingston, RI 

Kimberly P. Miller 2002A F, C 

Department of Epidemiology and Preventive Medicine, 

University of Maryland School of Medicine, Baltimore, Maryland 

Paul Herrera 2002C M, H 

Postdoc. Research Assoc., Poultry Science, TAMU College 

Station, TX 

Michelle D. Pine 2002C F, C 

Clinical Asst. Professor, Vet. Integrative Biosciences, TAMU, 

College Station, TX 

Mark T. Wormke 2002C M, C 

Research Scientist, GSF Institute of Toxicology, Neuherberg, 

Germany 

Anca D. Petrescu 2003A F, I 

Postdoc. Research Assoc., Vet. Physiology & Pharmacology, 

TAMU, College Station, TX 

Leslie C.H. Cizmas 2003B F, C 

Research Asst. Professor, School of Rural Public Health, 

Texas A&M Health Science Center, College Station, TX 

Kyounghyun Kim 2003C M, I 

Postdoc. Research Asst., Pharmacology, Univ. of California, 

San Diego, CA 

M. Derek Morrow 2003C M, C 

Research Scientist, Toxicology, Preclinical Services, Charles 

River Laboratories, Sparks, NV 

E. Spencer Williams 2003C M, C Health Scientist, ChemRisk, Inc., Houston TX 

Maen A. Abdelrahim 2004A M, I 

Research Scientist, Cancer Research Institute, MD Anderson 

Cancer Center, Orlando, FL 

Gary C. Barbee 2004A M, C 

Asst. Professor, Agronomy, Louisiana State Univ., Baton 

Rouge, LA 

Karin T. Lum 2004A F, A Defense Intelligence Agency, Alexandria, VA 

Carol Swartz 2004A F, C 

Research Staff, Comparative Pathobiology Group, NIEHS, 

Research Triangle Park, NC 

Kelcey M. Walker 2004A F, C Full-time mother, Swampscott, MA 

Melinda C. Wiles 2004B F, C 

Diagnostic Analytical Chemist, Texas Vet. Med. Diagnostic 

Laboratory, College Station, TX 

Evans Afriyie-Gyawu 2004C M, I 

Postdoc. Research Assoc., Vet. Integrative Biosciences, Texas 

A&M Univ., College Station, TX 

Jeong Eun Lee 2004C F, I 

Research Fellow, Massachusetts General Hospital, Harvard 

Medical School, Charlestown, MA 

Xiangrong Li 2005A M, I 

Postdoc. Research Assoc., Vet. Physiology & Pharmacology, 

TAMU., College Station, TX 

Xuhong Liu 2005A F, I 

Postdoc. Research Assoc., Neuroscience & Exp. Therapeutics, 


Michael Neerman 2005A M, C Director, North Texas Poison Center, Dallas, TX 

Maya M. Scott 2005A F, B 

Clinical Asst. Professor, Vet. Physiology & Pharmacology, 

TAMU, College Station, TX 

Sairam Bellum 2005C M, I Assoc. Toxicologist, Lexicon Genetics Inc., The Woodlands, TX 

Bhagirathi Dash 2005C M, I 

Postdoc. Research Fellow, Dept of Environmental Health 

Sciences, Univ. of California-Berkeley, Oakland, CA


Charles R. Partridge 2005C M, C 

Postdoc. Research Assoc., Univ. of Louisville Medical Center, 

Louisville, KY 

Wonsuk Yang 2005C M, I 

Postdoc. Research Assoc., Dept. of Neurology, Univ. of 

Chicago, Chicago, IL 

Annika M. Gillespie 2006A F, C Seeking employment in the Baltimore, MD area 

Chien-Cheng Chen 2006B M, I 

Postdoc. Research Assoc., UT Southwestern Medical Center, 

Dallas, TX 

Hyeong-Il Kwak 2006C M, I 

Postdoc. Research Assoc., Molecular & Cellular Medicine, 


Wan-Ru Lee 2006C F, I 

Postdoc. Research Assoc., UT Southwestern Medical Center, 

Dallas, TX 

Tracie D. Phillips 2006C F, C 

Toxicologist, Texas Commission on Environmental Quality, 

Austin, TX 

* F = Female, M = Male; A = Asian, B = African American, C = Caucasian, H = Hispanic, I = International 

Table 5. Graduate Profile, 1998-2006 – Gender and Ethnicity 

Domestic - Caucasian Domestic - Non-Caucasian International Total 

Female Male Female Male Female Male 

PhD 15 11 6 5 10 14 61 

MS 3 1 1 0 1 1 7 

Total 18 12 7 5 11 15 68 

4.E. Benchmarks Used by the IFT to Determine Whether Goals Are Being Met 

The IFT Executive Committee, through its regularly scheduled meetings, provides the primary 

mechanisms of assessment to ensure that the goals of the strategic plan are being met. At 

least twice per year, the primary focus of EC meetings is directed to recruitment and acceptance 

of new trainees and evaluation of the progress of the training program. Benchmarks used to 

assess that goals are being met include, but are not limited to: 

1. Number of overall applicants to the Toxicology Program (See Table 3 for a summary of 

the Toxicology graduate applicants). 

2. Quantitative evaluation of applicants (GRE scores, GPA and institution of previous 

degree) 

3. Number and percentage of applicants accepted each year 

4. Yearly attendance of faculty and trainees at local, regional, national and international 

meetings (e.g., See Appendix G for a summary of meeting participation and associated 

awards) 

5. Abstracts/presentations of faculty and trainees at local, regional, national and 

international meetings 

6. Awards to faculty and trainees for research presentations 

7. Graduate student scholarships (internal and external) 

8. Graduate student awards (internal and external; examples of internal awards include 

Ethyl Tsutsui Award, Vice Chancellor Award in Agriculture, Association of Former 

Students Award, George Edds Award in Toxicology, etc.; e.g., See Appendix H for a list 

of current IFT graduate student awards and honors). 

9. Employment Records (Academic, Industry, Government) 

10. Faculty awards (e.g., see Appendix I for a list of faculty awards and honors). 

11. Faculty research productivity (See Appendix J for 2 page faculty biosketches). 

12. Trainee research productivity (e.g., See Appendix K for a listing of publications from 

current IFT trainees).


4.F. Documentation of Student Learning/Learning Outcomes 

The IFT has received notice in the Fall of 2006, that the Southern Association of Colleges and 

Schools (SACS) and the Texas Higher Education Coordinating Board (THECB) recommended 

that Texas A&M University develop unit-level plans detailing outcomes and status reports for 

academic programs and administrative units. The IFT has attempted to formulate a systematic 

process that connects the mission, goals, and objectives of a program with a range of 

measurable and related outcomes for the purpose of improving the program’s success in 

achieving its goals and meeting its mission which is outlined in our “Outcomes Assessment of 

the Toxicology Program Administered Through the Interdisciplinary Faculty of Toxicology” 

included as Appendix L. 

We seek the advice and recommendations of the Academic Program Review Team to assist us 

with the further development of this outcomes assessment instrument. This document was 

developed with the understanding that personnel to conduct outcomes assessment are limited 

by the administrative structure of the IFT and limited staff support. Consequently, the 

instrument takes into consideration that the Chair, Administrative Assistant and/or Executive 

Committee of the IFT must conduct elements of this assessment with limited resources. 

4.G. Student Input to the Review 

The IFT values the input of graduate students and postdoctoral fellows in the planning, decision 

making, and evaluation of the program. One graduate student, elected by students enrolled in 

the M.S. and Ph.D. programs in 

toxicology, is a member of the IFT 

Toxicology Graduate Student Satisfaction Survey 

Executive Committee. The student 

representative serves to provide the 

Overall Satisfaction with Program 

Executive Committee with the 

student's point of view on issues and 

Likelihood to Recommend Program 

decisions relevant to the Toxicology 

Support from Committee/Advisor 

Program, and to communicate 

Quality of Seminars 

student concerns to the Executive 

Committee. This allows the Executive 

Availability of Equipment/Expertise 

Committee to receive dynamic 

Applicability of Coursework to Research 

feedback from the students in the 

Compensation 

program and address concerns as 

they arise instead of after they 

Travel Opportunities 

become serious problems. Graduate 

Administrative Support 

students are also involved in 

Confidence in Finding Jobs 

selecting seminar speakers and have 

opportunities to meet with the 

Preparedness for Writing Papers/Grants 

speakers in small discussion groups 

Preparedness for Independent Research 

(see Appendix M for a typical 

Depth and Scope of Curriculum 

seminar speaker schedule). 

Figure 5. Results of the student 

survey conducted in the Fall 2006 

Semester. Scoring: 0 = poor, 1 

below average, 2 fair, 3 good, 4 very 

good, 5 excellent. 

Contribution of Curriculum to Knowledge 

Knowledge of Basic Toxicology 

0 1 2 3 4 5 

Satisfaction Rating


This allows the students to have more indepth 

discussions with the seminar speakers in a relaxed setting that is more conducive to 

extended discussion of the seminar topic than the more formal environment of the seminar 

itself. Student participation in seminar speaker selection and the opportunities that the students 

have to meet with the speakers encourages students to actively seek out speakers that they 

wish to meet with, and provides them with valuable insight into the current topics in their field of 

study as well as with professional contacts and networking opportunities. 

In preparation for the Self Study, one mechanism developed in consultation with the IFT 

Executive Committee to derive input in the evaluation/review of the program, was to have the 

IFT graduates students develop and carry out a survey of the Program. The Graduate Student 

member of the IFT Executive Committee, Mr. Brian Laffin, identified a subcommittee to develop 

and carry out the survey in the Fall Semester, 2006. The survey was designed to receive 

candid student commentary on every aspect of the Toxicology Program, and responses were 

anonymous to ensure that the most accurate gauge possible of the students' attitudes and 

concerns was received. Results of that survey were collected and complied by Mr. Laffin and 

the subcommittee and results were submitted to the Executive Committee for review and action. 

Results of that survey were collected and complied by Mr. Laffin and the subcommittee and 

results were submitted to the Executive Committee for review and action. Results of the review 

were incorporated into the Self Study and are summarized Figure 5, while additional details on 

the survey are shown in Appendix N. The students ranked their favorite courses as Metabolic 

and Detoxication Mechanisms, the Cell Biology Modules, and Biochemical Genetics. They 

thought the curriculum needs more emphasis on experimental methods, physiology/pathology 

and cellular signaling. 

4.H. Facilities for Research and Research Training 

Members if the IFT have high quality facilities and research space to conduct research and 

graduate research training as indicated by the extent of individual and programmatic extramural 

grants. In addition to individual facilities used for the conduct of research and graduate training, 

there are numerous research facilities supported at different administrative levels throughout the 

university. Several of the research facilities relevant to the IFT include facilities supported by 

the Office of the Vice President for Research. Other research facilities have arisen from the 

efforts of the IFT and include Core Facilities created or supported by the TAMU Superfund 

Basic Research Program and the Center for Environmental and Rural Health. 

Facilities supported through the Office of the Vice President for Research include: 

The Comparative Medicine Program 

This is a centrally administered support service for animal research and teaching programs at 

Texas A&M University, College Station. The facilities and services are available for all Texas 

A&M University, College Station campus affiliated faculty, staff, and students who have been 

approved to conduct animal research by the Institutional Animal Care and Use Committee 

(TAMU IACUC). CMP is accredited by the Association for the Assessment and Accreditation of 

Laboratory Animal Care, International (AAALAC, International) through its affiliation with other 

AAALAC-accredited TAMU programs. Facilities offer housing and care for most standard 

laboratory animals. Specialized housing can be provided for biohazard projects (ABSL I-III) and 

hazardous chemical projects. Varying degrees of animal isolation are available. Housing for 

large animal species is limited; however, various other campus animal care facilities can provide 

housing for large animals. In addition, a variety of services are provided to institutional 

personnel. These services include the procurement of animals and animal husbandry supplies,


provision of veterinary care, use of CMP surgical facilities, a polyclonal antibody production 

service, technical support services, and animal use training services. 

The Center for Chemical Characterization and Analysis 

This is a component of the Department of Chemistry and a research support facility partially 

funded by the Office of the Vice President for Research and Associate Provost for Graduate 

Studies. The Center provides state-of-the-art capabilities for organic and inorganic analysis and 

structural characterization. Four specialized laboratories each address a specific area of 

interest. The areas and laboratories include: 

The Elemental Analysis Laboratory, which provides research support in the area of elemental 

and trace analysis as well as service analyses to TAMU users, other university and government 

agencies and private industry. It is unique in that it features fast neutron activation analysis 

(FNAA) capabilities in addition to thermal instrumental neutron activation (INAA) using the 

University's Nuclear Science Center 1 MW TRIGA research reactor. In addition, the laboratory 

has recently added inductively-coupled plasma - mass spectrometry to its stable of facilities. 

The ICP-MS has been fitted with both conventional sample introduction hardware for solution 

work as well as a 213 nm laser ablation system for studying solids and surfaces. The laboratory 

is extensively used to benefit a wide variety of research programs, reporting some 50,000 

measurements completed each operational year. 

The X-ray Crystallography and Molecular Structure Laboratory, a full service X-ray Diffraction 

laboratory offering state of the art instrumentation for the analysis of solid materials. Our 

services include single-crystal, powder diffraction and small angle x-ray scattering analysis for 

Chemistry, Material Sciences and Pharmaceuticals. We are staffed by fully trained Ph.D. 

scientists who employ the most up to date diffraction and x-ray techniques. 

The Nuclear Magnetic Resonance Laboratory, which in addition to providing NMR services, has 

provision for X-Ray Crystallography, Mass Spectrometry, and Neutron Activation Analysis. The 

NMR Facility includes 9 superconducting spectrometer systems and 3 full time staff positions to 

support them with maintenance, user training, and spectroscopic service. Although this facility is 

physically housed within the Chemistry Department, it provides services to the entire campus 

community. 

The Mass Spectrometry Laboratory, which provides expertise in mass spectrometry to all TAMU 

research activities. This includes the analysis of organic compounds ranging from small 

molecules to large biological molecules including proteins, DNA, RNA, and natural products. To 

accomplish the research objectives, the LBMS maintains a complete inventory of routine and 

cutting-edge mass spectrometers. In addition, the LBMS research scientists are actively 

involved in the development of new analysis methods and techniques and the development of 

next-generation instrumentation for analysis and sample handling, including robotics and 

microfluidics. The activities within the LBMS are divided into three categories: (i) core research, 

(ii) applications, and (iii) training and dissemination. 

The Microscopy and Imaging Center 

The Microscopy and Imaging Center is supported by the Vice President for Research and 

serves a wide range of faculty and students at Texas A&M University in addition to researchers 

from outside of the University. The mission is to provide current and emerging technologies for 

teaching and research involving microscopy and imaging in Life and Physical Sciences on the 

Texas A&M campus and beyond, training and support services for electron microscopy, sample 

preparation, in situ elemental/molecular analyses, as well as digital image analysis and 

processing. An affiliated Materials Characterization Facility provides access to additional


instrumentation and expertise. The MIC promotes cutting edge research in basic and applied 

sciences through Research and Development activities and quality training and education 

through individual training and short courses. 

The Protein Chemistry Laboratory 

The Protein Chemistry Laboratory is a core resource facility created and funded under the 

auspices of the Office of the Vice President for Research. The laboratory has been established 

to support research in protein chemistry and molecular biology in the Texas A&M University 

System and to provide state-of-the-art instrumentation and technical expertise for the 

application of modern molecular biological technologies. The PCL is overseen by a committee 

that meets regularly to discuss issues relevant to the facility's operation. The laboratory 

operates as a fee-for-service facility and accepts samples on a first-come-first-served basis from 

faculty, scientists and students of Texas A&M, other educational institutions and industrial 

scientists. Main campus users are given preference whenever possible as the facility exists 

primarily to support of Texas A&M research. 

Center for Environmental and Rural Health 

The NIH-funded Center for Environmental and Rural Health (CERH) at Texas A&M University 

currently provides funding for discounted use of several university supported facilities and other 

Facility Cores including Genomics and Bioinformatics, Image Analysis, and Integrated Health 

Sciences Facility Cores. The directors of each of these Facility Cores are members of the IFT. 

Texas Institute for Genomic Medicine (TIGM) 

TIGM is a non profit institute established as a partnership between Texas A&M University, the 

Institute for Biosciences and Technology, and Lexicon Genetics, Inc., and was funded by a $50 

million grant from the Texas Enterprise Fund. Using patented technology developed by Lexicon, 

TIGM is creating a comprehensive knockout mouse embryonic stem cell library containing 

350,000 cell lines. When complete, the new library is expected to be the world’s largest 

collection of mouse embryonic stem cells that have been engineered for the study of gene 

function. Thus, researchers will now be able to identify critical genes that will facilitate 

development of new methods for treating diseases and improving human health. TIGM will then 

use this embryonic stem cell library to develop single-gene knockout mice. It is also important to 

point out that the leadership of IBT and TIGM also play a leadership role in the CERH: Dr. 

Richard Finnell, Acting President of TIGM is the Director of the CERH Environment & 

Reproduction Research Core; Dr. Robert Schwartz, Director of IBT, is a member of the CERH 

Environment & Reproduction Research Core; Dr. Stephen Safe, Director of the Center for 

Environmental and Genetic Medicine at IBT, is Director of the CERH Environment & Cancer 

Research Core and Deputy Director of the CERH; and Dr. Wallace McKeehan, Director of the 

Center for Cancer Biology and Nutrition at IBT, is a member of the CERH Environment & 

Cancer Research Core. Drs. Finnell and Safe are members of the IFT.


5. FACULTY 

5.A. Current Faculty 

The IFT consists of 51 faculty from 15 Departments and 5 Colleges and 2 affiliated laboratories 

(USDA and Texas Veterinary Medical Diagnostic Laboratory) at TAMU and faculty from 4 

Departments and 3 Units of the Texas A&M Health Science Center (TAMHSC). Although 

TAMU and the TAMHSC are independent entities of the Texas A&M System, the structure of 

the IFT accommodates students from both Institutions. Appendix O provides a list of all IFT 

members and their departmental, college and system affiliations. Abbreviated, 2-page 

curriculum vitae for individual IFT members are provided in Appendix J. The distribution of IFT 

by Department and Rank are summarized in Figures 6. 

VTPP 

12% 

Faculty Distribution by Department 

TAMHSC- 

Medicine 

8% 

ANSC 

6% 

VTPB 

8% VIBS 

20% 

CHEM 

6% 

STAT 

10% 

ANSC 

BCBP 

CHEM 

CVEN 

ENTO 

NUFS 

POSC 

PSYC 

SCSC 

STAT 

VIBS 

VLAM 

VTPB 

VTPP 

WFSC 

TAMHSC-Medicine 

TAMHSC-SRPH 

TAMHSC-IBT 

TVMDL 

USDA 

Non-Res 

Figure 6. Faculty 

Distribution by 

Department. There are 

XX departments plus 

associated laboratories. 

The departments with 

greatest representation 

are identified on the 

chart. The distribution of 

faculty by rank includes 3 

Distinguished Professors 

(6%), 25 Professors 

(48%), 11 Associate 

Professors (22%), 7 

Assistant Professors 

(14%), and 5 of other 

rank (10%). This 

represents 39 tenured 

faculty and 12 nontenured 

full-time faculty. 

Since the last review, there has been some turn-over of faculty at TAMU. During the period of 

1998 – 2006, other institutions were successful in attracting several key faculty including Dr. 

Ken Ramos, Professor, Veterinary Physiology and Pharmacology who served as Chair of the 

IFT from 1994-1995, and Director of the CERH from 1999-2003. In addition, Drs. John 

Bickham, Dawn Boothe, Nancy Keller, Ronald Tjalkens and Cody Wilson were all recruited to 

other institutions. Dr. Wilson retains an adjunct appointment in the IFT. During the same 

interval, ten faculty members retired, two are deceased and ten have withdrawn from the faculty 

as a consequence of periodic review of IFT participation and eligibility. The IFT has also 

experienced a period of growth as several new faculty have joined during this period. These 

additions are summarized in Table 6.


Table 6. New IFT Faculty (1998-2006) 

IFT Member Rank Department Date 

Alan Parrish Assistant Professor Systems Biology & Translational Medicine 1999 

Weston Porter Assistant Professor Veterinary Integrative Biosciences 2001 

Yanan Tian Assistant Professor Veterinary Physiology & Pharmacology 2001 

Shashi Ramaiah Assistant Professor Veterinary Pathobiology 2002 

Philip Mirkes Professor and Director Veterinary Physiology & Pharmacology 2004 

of the CERH 

Gladys Ko Assistant Professor Veterinary Integrative Biosciences 2004 

Clinton Allred Assistant Professor Nutrition and Food Science 2006 

5.B. Faculty Profile 

Of the 51 current faculty members of the IFT, 38 (75%) are male and 13 (25%) are female. The 

ethnic composition of the faculty is 43 Caucasian (84%), six Asian (12%), and two Latino (4%). 

5.C. IFT Involvement in Teaching 

Members of the IFT participate in the teaching of Core or Elective Courses in the Toxicology 

Graduate program. Other faculty have responsibilities for teaching courses administered 

through academic departments in the TAMU and TAMHSC systems. Current courses taught by 

IFT members are summarized in Appendix P. 

5.D. Research Support of IFT 

The IFT has developed a substantial base of research funding in support of individual research 

efforts as well as joint programs and collaborative research projects. See Appendix Q for 

details of current and recent funding. 

5.E. Joint Programs and Collaborative Research Projects with Other Units 

As discussed previously in Section 2.C., the IFT has established an internationally recognized 

program incorporating Environmental Health Research, Training, and Outreach at TAMU. The 

development of a national research and training identity has been enhanced by NIEHS 

supported programs including a Toxicology training grant (Section 2.C.1.), Superfund Basic 

Research Program Project (Section 2.C.2.), Center Grant (Section 2.C.3.), and outreach 

activities that are best organized in the Partnership for Environmental Education and Rural 

Health (Section 2.C.4.). Other interdisciplinary collaborations involving IFT members continue 

to be developed from these programs. 

5.F. Areas of Outstanding Performance 

Members of the IFT are active in professional associations, review panels, committees and 

have received recognition and awards for their teaching, research and other scholarly activities. 

See Appendix I for more information on faculty awards and honors.


5.G. Faculty Salaries 

As an intercollegiate faculty, IFT members have primary faculty appointments in academic 

departments where salary and merit compensation decisions are handled. Although the IFT is 

not involved in any matters concerning salary or merit raises, provided here in Table 7 are 

benchmark data from two departments (VIBS and VTPP) in which approximately one-third of 

the IFT have primary appointments. 

Table 7A. VIBS Faculty Salaries 

Fiscal Year 2006-2007 

Faculty Title Number VIBS Salary - Mean VIBS/IFT Faculty Mean 

Assistant Professors 10 (2) $73,574.10 $79,925.00 

Associate Professors 4 (1) $94,639.75 $96,738.00 

Professors 14 (5) $117,862.80 $131,515.00 

Table 7B. VTPP Faculty Salaries 

Fiscal Year 2006-2007 

Faculty Title Number VTPP Salary - Mean VTPP/IFT Faculty Mean 

Assistant Professors 10 (1) $79,910.00 $83,291.00 

Associate Professors 7 (1) $92,866.00 $102,153.00 

Professors 7 (2) $128,445.00 $147,278.00 

Promotion and tenure decisions are initiated by the department, and then submitted for 

evaluation at the college and eventually university levels. Faculty participation in the IFT is by 

“membership” rather than as an “academic appointment” as all IFT members have primary 

appointments in academic departments where promotion and tenure decisions are made. 

Consequently, the IFT has no formal responsibility for promotion and tenure decisions. 

However, the IFT Executive Committee has in the past and is currently prepared to provide 

written documentation, at the request of IFT members or departmental administrators, of their 

contributions to the program in support of departmental tenure and promotion considerations. 

In the past 5 years, for all faculty that IFT has been asked to provide input, tenure and 

promotion decisions have been positive.


6. STRENGTHS AND WEAKNESSES OF THE IFT 

Toxicology research and training at TAMU was initiated in 1970 and was housed in the College 

of Veterinary Medicine and Biomedical Sciences Department of Physiology & Pharmacology. 

The Interdisciplinary Faculty of Toxicology was initially developed to provide opportunities for 

graduate students outside the Department of Veterinary Physiology and Pharmacology to obtain 

an M.S. or Ph.D. degree in Toxicology. In 1990, the Texas A&M University Faculty Senate and 

the State Coordinating Board for Higher Education approved our request for reassigning 

administrative responsibility for the degree program from the Department of Veterinary 

Physiology & Pharmacology to the Interdisciplinary Faculty of Toxicology. Since then, 144 

students from ten departments and four colleges have now graduated from the Interdisciplinary 

Faculty (26 M.S. degrees and 118 Ph.D. degrees in Toxicology). The IFT has continued to 

serve as a major catalyst for a number of interdisciplinary collaborations that include the Texas 

A&M University Superfund Basic Research Program Project, the Center for Environmental and 

Rural Health, the Toxicology Training Grant, and Partnership for Environmental Education and 

Rural Health program. 

The effectiveness of the IFT highlights the value of an interdisciplinary degree which is a 

consequence of the need for increasingly sophisticated approaches to difficult research 

questions, as well as the accelerating pace of change in both society and scholarship. 

Employers value the skills and flexibility developed by multidisciplinary and interdisciplinary 

training, and our graduates adapt easily to positions in academia, government and industry. 

The catalytic effects of the IFT on both research and graduate education are directly related to 

other strengths of the program that are briefly summarized below. 

6.A. Program Strengths 

6.A.1. Graduate Education 

1. The IFT has attracted high quality applicants with excellent qualifications and prior research 

experiences; many other excellent graduate students recruited by other Departments have 

opted for a degree in Toxicology. Once enrolled, students have continued to excel. 

2. The IFT has developed a flexible degree program with excellent core courses. The flexibility 

of the Toxicology degree program permits graduate training to be tailored to individual 

students, taking into account their unique backgrounds and professional goals. 

3. The IFT has a diverse faculty with broad representation from different disciplines. 

Correlated with this is the outstanding teaching expertise of the IFT as lead instructors in IFT 

Core Courses who are active, funded researchers. Good teaching is supported in at the 

college and university level by the availability of funds for new projects or teaching 

endeavors through the Center for Teaching Excellence. 

4. Enrichment programs sponsored by the Faculty are a major strength in our graduate 

training. The IFT sponsors a high quality Fall and Spring weekly seminar program (see 

Appendix E). Although most visiting speakers present their current research activities, we 

also routinely include scientists who discuss research and employment opportunities in 

industry and the public service. Graduate students are also required to participate in the 

annual Toxicology Graduate Student Forum. In addition, the IFT sponsors student 

attendance at the Gulf Coast and national Society of Toxicology meetings and this activity 

constitutes the largest expenditure from the faculty budget reflecting the importance 

attached to this component of the enrichment program.


5. IFT students have access to excellent core facilities, equipment and laboratory space. 

Faculty have been very receptive to providing access to specialized equipment and 

technology transfer between laboratories by sharing protocols and reagents. 

6.A.2. Research 

1. Development of the IFT has greatly expanded the initial research focus from Veterinary 

Toxicology to multiple areas of this discipline including (a) Reproductive and Developmental 

Toxicology, (b) Behavioral and Neurotoxicology, (c) Cellular and Molecular Toxicology, (d) 

Applied Veterinary and Food Toxicology, and (e) Environmental Health Sciences. The 

diverse faculty research interests allow graduate students to select advisors with a broad 

range of research activities and this continues to be a major strength of the program. 

2. The expanded research focus of the IFT is the result of an exceptionally talented, well 

funded and well apportioned faculty to serve its multidisciplinary research (and teaching) 

missions. IFT members provide scientific leadership in directing interdisciplinary programs, 

by directing research policy and funding through service on Study Sections or as ad hoc 

reviewers for federal and private funding agencies, as members of editorial boards and as 

ad hoc reviewers for scientific journals. Members of the IFT also serve in positions of 

leadership in professional societies, as organizers of symposia and as coordinators of 

regional research consortia. 

3. As noted above, The IFT has continued to serve as a major catalyst for a number of 

interdisciplinary collaborations that include the Texas A&M University Superfund Basic 

Research Program Project, the Center for Environmental and Rural Health, the Toxicology 

Training Grant, and Partnership for Environmental Education and Rural Health program. 

These programs and the collaborative/collegial interactions of the Faculty have fostered a 

sense of a Toxicology community among members who are administratively divided by 

colleges and departments as well as physically separated in laboratories scattered across 

the TAMU campus and other campuses. It is recognized as a model for other 

Interdisciplinary Faculties on the Texas A&M University campus and as a Signature 

Program in the College of Veterinary Medicine and Biomedical Sciences. 

4. Members of the IFT have excellent research space and high quality research resources and 

core facilities, many of which are the direct results of their efforts to maintain Center and 

Program Project funding. These programs have given the IFT a mechanism and clear voice 

in identifying needs, shaping infrastructure resources, and promoting collaborations within 

and outside of the IFT. 

5. The IFT has facilitated faculty recruiting because it expands both research and training 

opportunities for faculty who are being recruited to traditional departments. 

6.A.3. Administration 

1. The leadership by the various Chairs, Executive Committees and Administrative Assistant 

has also been an important strength of the IFT. This leadership includes junior members of 

the IFT as 3 of 7 members of the current Executive Committee are Tenure Track Assistant 

Professors. All of the activities of this program have been borne by many individual faculty 

members to further the quality of graduate education and research in Toxicology. These 

activities have been willingly carried out by faculty without any financial rewards or academic 

credit within their respective Departments. 

2. Initial financial support by the College of Veterinary Medicine and Biomedical Sciences was 

instrumental for development of this program, and current financial support from the Office 

of the Vice President for Research and Graduate Studies in cooperation with the Council of 

Participating Deans has enabled the Faculty to maintain its activities. This funding supports


our administrative assistant, seminar program, recruitment and enrichment activities; 

participating faculty do not receive any of this financial support. 

3. The IFT has served as a focal point for graduate research and education and for 

development of externally funded collaborative programs. Mechanisms for involvement of 

the faculty in recruitment and hiring of new faculty or for tenure/promotion of existing faculty 

in various departments have been improved and this is due, in part, to excellent interactions 

with Department Heads. 

6.B. Program Weaknesses 

The strengths and weaknesses of Interdisciplinary Faculties are dependent primarily on the 

faculty, students and leadership of individual Faculties. However, there are a number of generic 

problems shared by all Faculties at TAMU and many of these are due to the failure to provide 

long-term assured financial funding for Faculties. At present, the administration of this 

University currently recognizes Colleges and Departments as the prime academic units of this 

institution thus leaving Interdisciplinary Faculties in a precarious situation with a number of 

weaknesses that are noted below. The first two weaknesses have previously been spelled out 

by the Molecular and Environmental Plant Sciences Program in their Self Study prepared for a 

May, 2006 External Review. These weaknesses have been modified slightly here to reflect the 

specific issues affecting the IFT. 

1. Student designation in Interdisciplinary Programs: As part of the changes in how 

intercollegiate degree programs are administered, interdisciplinary students are now 

identified in the university’s student database as affiliated with the COFD (Council of Deans) 

rather than the college of their major advisor. This has created some unexpected 

consequences, as well as unintended friction between the departments and Interdisciplinary 

Faculties. Departments are concerned about not receiving credit for the students that their 

faculty are training. For example, when reports are run, COFD students no longer show up 

as being affiliated with a department or specific college. Students also graduate with COFD 

programs now, which often causes them to participate in different graduation ceremony 

(time and sometimes day) than that held for the primary college of their advisor. While much 

of the problem is associated with ‘software’ limitations, and assurances have been made 

that the new information management system will sort out these problems, it remains 

imperative that we do not ‘divorce’ the interdisciplinary students from their advisor’s 

department and college. The students benefit from their association with the departments 

and colleges, just as the colleges and departments benefit from the existence of the 

interdisciplinary programs. Now that the IDP students are categorized as COFD, there have 

been communication gaps and missed opportunities that are negatively impacting the 

students. Some information regarding administration of academic degree programs (new 

policies, updates on various issues, deadlines, etc.) is still only disseminated to departments 

or through committees where only departments are represented. A related issue is that 

some opportunities only come through departments; i.e. award nominations, some funding 

sources (i.e. computer access fees). While it is understandable that interdisciplinary Faculty 

students will need to be considered separately from departmental students for programs 

where both Interdisciplinary Faculties and departments receive funding, the administration 

will need to be clear with the units when a particular type of funding is flowing strictly through 

departments. 

2. Administration of Interdisciplinary Programs: The creation of the Council of Deans (COFD) 

and Council of Participating Deans (COPD) was an effort by TAMU to develop an 

administrative framework to deal with interdisciplinary programs at the university. Direct 

interaction between individual Interdisciplinary Faculties and the COPD/COFD has been


limited to program reviews which occur yearly. The office of the Vice President for Research 

has served as a liaison between the Interdisciplinary Faculties and the Deans, but there 

appears to be an aura of ambiguity (even amongst some of the Deans) as to membership of 

the COPD, and expectations and responsibilities of the COPD/COFD with regard to the 

Interdisciplinary Faculties. 

3. Funding for the IFT: Funding for the IFT is derived from multiple sources (see budget) and 

there is no fixed recurring funding line or operational budget. The above referenced 

administrative organization of the Interdisciplinary Faculties was developed to monitor the 

progress of the faculty on an annual basis and address the issue of stable funding, however, 

funding continues to trickle in throughout the year to support the program. 

4. Incentives and Reward Structure: While an evaluation measure of the IFT is in place for 

justifying annual funding of the program, incentives and a reward structure for faculty 

members involved in interdisciplinary activities, particularly administrative/leadership duties 

supporting the IFT and related centers, research and training programs have not been 

developed. Further, requirements for increased record keeping, development and 

implementation of unfunded mandates such as Outcomes Assessment instruments and 

requests for information from agencies carrying out assessments of academic programs 

continue to add to the workload in the absence of recognition and/or compensation for these 

efforts. 

5. Funding for Incoming Students: A major weakness of the Faculty of Toxicology has been the 

inability to control teaching/research assistantships for incoming graduate students enabling 

them to participate in laboratory rotations prior to selection of a research advisor. Regents’ 

Fellowships have been used to support laboratory rotations for a few incoming students. 

6. Tuition Assistance: Graduate students at TAMU receive no tuition waivers unless they are 

supported by departmental teaching assistantships. The IFT has no graduate teaching 

assistantships and therefore IFT are responsible for covering graduate student tuition. 

7. The Faculty of Toxicology has made only minimal contributions to the undergraduate 

Biomedical Science program and coordinated involvement with course work and student 

research relationships have been lacking. 

In conclusion, it must be noted that many of the weaknesses noted above are associated with 

the complex administrative status of Interdisciplinary Faculties at Texas A&M University. There 

has been considerable interest in resolution of this problem by the Executive Associate Vice 

President for Research, Dr. James Calvin and the Dean of the Office of Graduate Studies, Dr. 

John Giardino, and their colleagues. Enhancing interdisciplinary research and graduate 

education will play a key role in improving the academic status and recognition of Texas A&M 

University. It is clear that the goals of Vision 2020 can be attained only if the problems of 

Interdisciplinary Faculties are finally resolved.

Appendix A 

Administrative Framework for 

Interdisciplinary Programs

UNIVERSITY RULE 

15.01.99.M7 

Administrative Framework for Interdisciplinary 

Programs 

Approved December 14, 2006 

1. GENERAL 

1.1 An Interdisciplinary Research Program (IRP) involves a group of faculty, 

from more than one discipline representing single or multiple colleges, 

organized and administered by the procedures outlined in this rule for the 

purpose of enhancing research and scholarly activities beyond what is 

possible through the traditional administrative structure. 

1.2 An Interdisciplinary Degree Program (IDP) involves a group of faculty 

from more than one discipline representing single or multiple colleges, 

organized and administered by the procedures outlined in this rule for the 

purpose of enhancing research and scholarly activities and overseeing 

graduate and/or undergraduate education for a degree program that does 

not exist in an existing academic unit. The approval of the 

interdisciplinary degrees themselves are approved through the normal 

degree approval process. 

2. ESTABLISHING INTERDISCIPLINARY PROGRAMS 

2.1 For a group of faculty to establish an IRP or IDP, they must; 

2.1.1 Develop a set of bylaws for the IRP or IDP including a mission 

statement, membership criteria, and procedures for selecting an 

Executive Committee (EC) and its leadership (e.g., a chair or cochairs). 

2.1.2 Identify a department or set of departments (called sponsoring 

departments) and the corresponding colleges (called sponsoring 

colleges) to act as advocates for the proposed program during the 

creation/evaluation process. 

2.1.3 In conjunction with the sponsoring units, identify a department in 

which the IRP or IDP will reside administratively. This 

department is called the administrative department, and the 

corresponding college is called the administrative college. 

2.1.4 Submit a proposal for the establishment of the IRP or IDP 

containing the items in Section 2.2 of this rule. This proposal 

originates with the faculty group seeking to establish the IRP or 

IDP and is routed for approval through: 

15.01.99.M7: Administrative Framework for Interdisciplinary Programs Page 1 of 3

a. The sponsoring department heads, through 

b. The sponsoring deans, through 

c. The Dean of Graduate Studies (DGS) if the proposal 

includes a graduate degree program, and/or the Associate 

Provost for Undergraduate Programs (APUP) if the 

proposal includes an undergraduate degree program, 

through 

d. The Vice President for Research (VPR), to 

e. The Executive Vice President and Provost 

2.2 The proposal for establishing an IRP or IDP must contain the following 

items: 

2.2.1 The rationale for the creation of the IRP or IDP. 

2.2.2 The bylaws described in Section 2.1.1 of this rule; including the 

identification of the administrative units as described in Section 

2.1.3 and listing roles and responsibilities of the administrative 

units. 

2.2.3 A description of the Council of Participating Deans (COPD) which 

consists of the deans of the colleges having faculty participating in 

the IRP or IDP, together with the VPR, and the DGS for IDP’s 

offering graduate degrees and/or the APUP for IDP’s offering 

undergraduate degrees. One of the college deans, to be selected by 

the COPD, will serve as the lead dean. 

2.2.4 A list of the participating department heads (PDH), that is, the set 

of department heads having faculty participating in the IRP or IDP. 

2.2.5 A budget (and budget justification) for the operating costs of the 

IRP and IDP. 

2.3 The Executive Vice President and Provost, in consultation with the COPD, 

will make the final decision as to whether the proposed IRP or IDP should 

be established. Establishment of and funding for the operating budget is 

the collective responsibility of the COPD and other participating units. 

3. PROGRAMMATIC REVIEW 

Annual reports will be submitted to the COPD who will ensure that the report is 

distributed appropriately. A yearly meeting of the COPD, PDH, and EC will be 

held. Additional meetings may be called at the discretion of the COPD. 


3.1 It is responsibility of the COPD to establish a review schedule. This 

review will involve the COPD, PDH, and EC. 

3.2 As part of the normal annual review of faculty, each participating 

department head will review with each of their involved faculty members 

their future level of participation in the IRP or IDP as well as the results of 

their previous participation. These discussions may be incorporated into 

promotion, tenure, and merit raise decisions. 

3.3 A rigorous periodic review of all IDP’s and IRP’s will be conducted by 

the Office of the Executive Vice President and Provost to determine if the 

program is performing successfully and if it should be continued. In 

addition, graduate degrees granting IDP’s will also be externally reviewed 

as part of the University’s academic program reviews. 

4. COORDINATION OF INTERDISCIPLINARY PROGRAMS WITH 

OTHER MEMBERS OF THE TAMU SYSTEM 

IRP or IDP efforts may include faculty from other Texas A&M University System 

members as outlined in the program’s bylaws. A memorandum of understanding 

must be initiated between the System member(s) and Texas A&M University, as 

represented by the Vice President for Research, to establish the level of 

participation of the System member(s) in the IDP or IRP. 

OFFICE OF RESPONSIBILITY: 

Vice President for Research 


Appendix B 

2006 PEER Perspectives: 

Broadening the Reach of University 

Resources by Advancing STEM (Science, 

Technology, Engineering and Mathematics)

PEER Perspectives 

2006 

Broadening the Reach of University Resources by Advancing STEM 

Lesson plans and novice teaching tips for middle schools; PEER 

research findings; graduate, undergraduate, and faculty testimonials 

GK-12 

Virginia Traweek and Larry Johnson 

Department of Veterinary Integrative Biosciences, Texas A&M University 

College Station, Texas 77843-4458

Letter from the chief investigator: 

My involvement in public schools started when I attended an open house at my son’s 

middle school in 1994. His teacher asked for scientists to serve as guest speakers to 

promote science and careers. I began routinely presenting a talk on the “Health of 

the Respiratory System” using anatomical specimens from the Texas A&M University 

College of Veterinary Medicine and Biomedical Sciences and attending career 

days as a college professor and scientist. I was asked by the Center for Environmental 

and Rural Health (CERH) at Texas A&M to submit a grant proposal (CERH is 

funded by the National Institute of Environmental Health Sciences (NIEHS)), as part 

of an outreach effort to help translate environmental health science research findings 

from CERH scientists into a form that was usable by K-12 schools. 

We assembled a team of scientists, veterinarians, educators, and staff to prepare 

the grant proposal. We received our first grant for a program directed at increasing 

interest in environmental health science in rural middle schools. Our approach was 

to produce an environmental health science curriculum, train teachers, and sponsor 

scientists’ visits to rural middle schools. We dubbed ourselves the Partnership 

for Environmental Education and Rural Health (PEER). In our first year, NIEHS 

requested grant applications for a seven-year grant that integrated environmental 

health science with science, mathematics, English language arts, and social studies. 

We added new members to the PEER team, including faculty experienced in those 

areas. We obtained a second grant from NIEHS that allowed integrated curriculum 

development, teacher training, and scientists’ visits to schools. 

Since that time, PEER has produced three life science and environmental health/ 

toxicology online curriculum modules. We also created 14 additional modules that 

integrate environmental health science into middle school science, mathematics, 

English language arts, and social studies. A group of 804 teachers has been 

trained through our workshops and 1,522 teachers and 35,000 students have 

experienced PEER scientists’ visits to their schools. The NSF GK-12 project 

was brought into PEER as a means of placing science, technology, engineering, 

and mathematics (STEM) role models and enhanced instruction in more 

rural K-12 schools. In our GK-12 program, 22 Graduate Fellows have served 

as STEM content resources for 56 teachers and 6,910 students in local rural 

schools; mentored University Honors Undergraduate Fellows; and produced 

138 customized lesson plans that are available to all rural schools through our 

Teacher-Requested Resources. Broader impacts of PEER activities include 

broadening the reach of university resources to rural schools to advance discovery, 

enhance scientific and technological understanding, and provide STEM 

career knowledge and opportunity for all middle school students. 

This monograph provides the “PEER Perspective” on institutions of higher 

education partnering with rural schools. PEER’s mission is to provide resources 

and role models in the four STEM subject areas for schools with limited 

access to university-level science and mathematics inspiration. The goal of 

this publication is to document and share experiences and accomplishments of 

university faculty and students. We also present research findings and useful 

resources, including lesson plans and tips for new teachers. Here teachers can 

see a glimpse of what awaits them at http://peer.tamu.edu. 

About Dr. Johnson: 

Larry Johnson, professor in the 

Department of Veterinary Integrative 

Biosciences at Texas A&M University, 

has published over 110 original, peerreviewed, 

scientific journal articles; 

given invited scientific talks on four 

continents; won a national research 

award; served on a research panel for 

the United States Congress; served on 

NIH, NSF, USDA, and NIOSH grant 

review panels; received NIH and/or 

NSF funding for over 25 years; served 

on editorial boards of three scientific 

journals; and received both college-level 

and university teaching awards for his 

histology courses. He also coordinates 

a graduate course on scientific ethics 

and recently initiated a graduate course 

and veterinary school elective on 

the development of communication, 

organization, and mentoring skills 

through public school outreach training 

and experiences. 

Sincerely, 

Larry Johnson, Ph.D. 

Dr. Larry Johnson displays two lung casts illustrating 

highly branched airways of lungs. 

2 PEER Perspectives 2006

Larry Johnson 

Principal Investigator, PEER 

Voice: 979-845-9279 

E-mail: ljohnson@cvm.tamu.edu 

Jim Kracht 

Co-Principal Investigator, PEER 

Social Studies Specialist 

Voice: 979-845-8364 

E-mail: jimkracht@tamu.edu 

William Klemm 


Voice: 979-845-4201 

E-mail: WKlemm@cvm.tamu.edu 

G. Donald Allen 


Voice: 979-845-7950 

E-mail: Don.Allen@math.tamu.edu 

Jimmy Lindner 


Evaluation Specialist 

Voice: 979-458-2701 

E-mail: j-lindner@tamu.edu 

Jon Hunter 

Co-Investigator, PEER 

Mathematics and Engineering 

Voice: 979-862-1024 

E-mail: jhunter@cvm.tamu.edu 

Table of Contents 

Part I: Research Findings 

Page Article 

4 PEER Overview 

5 Project Products 

6 Lessons Learned 

7 PEER Curriculum: Experiences 

in Caldwell Middle School 

8 Golden Nuggets 

9 Snook: Science Bowl Victory 

10 PEER and GK-12 Improve 

Middle School Teaching 

11 A GK-12 Experience in 

Mathematics 

12 The Death of “Drill and Kill” 

13 Dr. Bill, Memory Medic 

14 Scientists’ Visits 

16 Southwest Regional GK-12 

Meeting 

17 The Making of a 

“Mathemagician” 

17 Value of Scientists in Public 

Schools 

18 First-Year Classroom 

Improvement 

Page Article 

19 The Making of Free Teacher- 

Requested Resources 

20 Adventures of an Undergraduate 

Fellow 

21 Teaching Philosophy of a 

Scientist 

21 “Wings Across Texas” Report 

Part II: Lesson Plans, Teacher Tips, 

and Worksheets 

Page Article 

22 Under Pressure: Calculating 

Surface Area 

25 Crank Up the Volume! 

29 Folding in the Scientific Method 

30 Rational Code Cracking 

32 Shoebox Apartments 

34 Walk This Way 

36 Sequence Races 

40 How Low Can You Go? 

43 Seasonal Mathematics 

47 Novice Teacher Corner 

Deborah Kochevar 


English Language Arts Specialist 

Voice: 979-845-5700 

E-mail: dkochevar@cvm.tamu.edu 

K. C. Donnelly 


Voice: 979-845-7956 

E-mail: k-donnelly@tamu.edu 

Vince Hardy 

PEER Coordinator 

Voice: 979-845-8339 

E-mail: vhardy@cvm.tamu.edu 

Jeremiah McNichols 

Graphics Specialist 

Voice: 979-458-0521 

E-mail: JMcNichols@cvm.tamu.edu 

Shawn Martin 

Middle School Teacher 

Voice: 979-458-4048 

E-mail: Smartin@cvm.tamu.edu 

Virginia Traweek 

Graphics Specialist, GK-12 Fellow 

E-mail: VirginiaTraweek@neo.tamu.edu 

Editors: Virginia Traweek and Larry Johnson 

Contributors: G. Donald Allen, Candace DiBiano, Kevin Curley, Shannon Degenhart, K.C. 

Donnelly, Jan Fechhelm, Jon Hunter, Larry Johnson, Michael Karka, Bill Klemm, Kelly 

Lazo, Danielle Lewis, Marta Kobiela, Shawn Martin, Diana Mowen, John Nelson, Bruce 

Ngo, Ryan Pedrigi, Melanie Ramon, and Virginia Traweek 

This monograph is published by the Partnership for Environmental Education and 

Rural Health (PEER). PEER is funded by grants from the National Science Foundation 

(Grant # 0338310) and the National Institute of Environmental Health Sciences 

(Grant # ES 10443-03, ES 10735-06), cost-sharing of Texas A&M University and the 

Department of Veterinary Integrative Biosciences, and support for GK-12 Undergraduate 

Fellows from the Texas A&M University Honors Program. 

Copyright pending. 

About Virginia Traweek: 

After beginning work as a GK-12 Undergraduate Fellow, Virginia 

Traweek is now a GK-12 Graduate Fellow involved in graphics and 

dissemination. Upon completion of her Bachelor of Environmental 

Science degree in architecture last August, she began studying for a 

Master of Science in Finance. She expects to graduate in May 2007. 


Quick Definitions 

PEER- the Partnership for Environmental 

Education and Rural Health; outreach 

component of CERH. Visit peer.tamu. 

edu for more information. 

NSF- the National Science Foundation, 

which supplies part of PEER grant funding. 

Visit www.nsf.gov for more information. 

NIEHS- the National Institute of Environmental 

Health Sciences, which supplies 

part of PEER grant funding. Visit www. 

niehs.nih.gov for more information. 

CERH- the Center for Environmental 

and Rural Health, parent organization of 

PEER, with the goal of promoting rural 

health awareness. Visit cerh.tamu.edu 

for more information. 

NSF GK-12 Graduate Fellow- A Texas 

A&M University science, technology, 

engineering, or mathematics graduate 

student who works in a local middle 

school classroom assisting math and 

science teachers. Known as a Resident 

Scientist/Mathematician. 

NSF GK-12 Undergraduate Fellow- an 

undergraduate student at Texas A&M 

University who serves as support for a 

Resident Scientist/Mathematician and 

assists in developing activities for use in 

middle school classrooms. 

Resident Scientist/Mathematician- NSF 

Graduate Fellow who acts as a content 

specialist in his or her middle school 

classroom. Teachers are asked to carefully 

distinguish student teachers from 

Resident Scientists and Mathematicians. 

STEM- Science, technology, engineering, 

and mathematics, the areas of 

education where American children 

perform below the world average. 

Lead Teacher- a teacher with whom the 

Graduate Fellow is assigned to work 

directly in his or her classroom. 

TEKS- Texas Essential Knowledge and 

Skills, Texas educational standards for 

each grade level. 

TAKS- Texas Assessment of Knowledge 

and Skills, Texas’ benchmark test for 

academic proficiency. 

4 PEER Perspectives 2006 

PEER Overview 

Goals and Roles of the PEER GK-12 Program 

Larry Johnson and Virginia Traweek 

Goals of the PEER GK-12 program 

are to enhance interest in learning, 

to improve academic performance of 

K-12 students, and to enrich graduate 

education. The project hopes to inspire 

the next generation of researchers in 

academia, industry, and government 

to become aware of and sympathetic 

to the challenges and opportunities 

in K-12 education, and of how they 

can contribute and improve the 

science, technology, engineering, and 

mathematics (STEM) content and interest 

of K-12 students and teachers. 

Objectives are to: 

1. Enhance students’ opportunities to 

learn STEM content by increasing access 

to inquiry-driven experiences in content 

areas from national and state educational 

standards; 

2. Assist teachers in gaining more 

interest, knowledge, and confidence in 

teaching science and mathematics; 

3. Provide middle school students with 

diverse STEM role models; 

4. Improve student attitudes toward 

science and mathematics; 

5. Help GK-12 Fellows improve 

pedagogical, communication, and 

teamwork skills, thus enhancing future 

career opportunities; 

6. Provide resources to rural schools 

throughout Texas via 

a distance learning 

community and 

worldwide resources 

through the PEER 

website; 

7. Assess the shortterm 

and long-term 

impacts of the 

program on middle 

school students, their 

teachers, and GK-12 

Resident Scientists; 

8. Assess the 

educational 

materials produced 

and educational 

partnerships 

established; 

9. Facilitate long-term interactions 

between teachers, teacher educators, and 

university scientists; and, 

10. Facilitate a long-term, sustainable 

interface between Texas A&M and public 

schools. 

Roles of participants in the 

GK-12 program: 

The main players are the GK-12 

Graduate Fellows (Resident Scientists/ 

Mathematicians) and Lead Teachers. 

The GK-12 Graduate Fellow 

provides STEM content expertise, 

demonstrations/presentations, materials 

and resources, and acts as a conduit to 

university faculty and resources. They 

serve as an example of scientific and 

mathematical thinking and as a role 

model of someone who enjoys and plans 

to make a career in STEM. 

The Lead Teacher assists the 

GK-12 Fellows in meeting school needs, 

organizes and obtains resources, mentors 

the Fellows, and communicates to 

project managers how things are going 

in the school and what is missing. Lead 

Teachers mentor and provide teaching 

opportunities for the Graduate Fellows. 

• 

NSF GK-12 Graduate Fellow, Kevin Curley Jr., and GK-12 Undergraduate 

Fellow, Nathan Shepard, address a science class.

Project Products 

Larry Johnson 

Project products include human capital 

and teacher resources. 

Human Capital: 

Personal interface between 

Graduate Fellows, K-12 students and 

teachers has been found to have a 

positive influence on the Fellows, K-12 

students, and teachers and has forged sustainable 

partnerships between participating 

schools and Texas A&M University. 

Distance learning community 

extends the impact of the project 

into rural Texas and beyond by providing 

online lessons in a searchable database. 

Other PEER K-12 

Connections 

- Middle school drawing and essay contest: PEER, in partnership with Sigma Xi 

and the Texas A&M University Distinguished Lecture Series, sponsors a yearly 

essay and drawing contest for middle school students. Topics change from year 

to year and are related to the spring lecture series topics. 

- Science fair judging: PEER undergraduate and graduate students travel to local 

science fairs to assist with judging. 

- Science Sleuths Summer Camp: PEER offers a two-week summer camp for 

middle school students that incorporates PEER integrated curriculum modules 

to solve a mystery. 

- Virtual scientists’ presentations: PEER’s website offers online videos by Texas 

A&M University scientists. The videos cover topics related to anthrax, toxicology, 

the respiratory system, the scientific method, and scientists in the classroom. 

Southwest Regional NSF GK- 

12 Meeting was an annual conference 

devoted to sharing of resources; 

hosted and organized by PEER and attended 

by 10 GK-12 groups in five states, 

as well as Dan Carpenter and Sonia 

Ortega of NSF. 

NSF Fellows’ presentations 

are posters presented at the 2005 Southwest 

Regional NSF GK-12 Meeting by 

13 of 15 Graduate Fellows and two Lead 

Teachers detailing specific activities, 

evaluation findings, and successful strategies 

of the GK-12 program. 

To demonstrate cutting-edge scientific 

(STEM) research methods in the classrooms, 

70% of our Fellows gave presentations 

on their specific research projects 

in their routine teaching presentations. 

Introductory videos were 

produced at the beginning of each school 

year to help middle school students understand 

their Fellow’s area of research. 

These were presented before the Fellows 

attended class. As a result, the K-12 

students saw their future Fellow in their 

scientific research role, talking about 

their daily activities including the specific 

research (cutting-edge STEM) of their 

graduate program, and enjoying hobbies. 

The Fellow’s introductory video 

enhanced familiarity with the university 

and helped set up visits to the university 

by K-12 students of partner schools. 

Faculty and teacher presentations 

on the GK-12 outreach efforts 

were given by the teachers and faculty at 

state and national conferences at a rate of 

six to 12 per year. 

Project evaluation mechanisms 

were developed for Fellows, 

Lead Teachers, and K-12 students so that 

PEER could measure progress. PEER 

also uses a career tracking system for 

previous Graduate Fellows. 

Science and math courses 

(VIBS 689 and MATH 689) were developed 

to train other interested graduate 

students who are not part of the GK-12 

program. This helps STEM faculty in 

determining “Broader Impacts” of their 

own research grants or career development 

awards. 

University funding for outreach 

includes three Undergraduate Fellows per 

year (about $9,000) by the Texas A&M 

University Honors Program and over 

$400,000 in cost-sharing contributed 

by the Office of the Vice President for 

Research. 

Interface with the Sigma Xi 

Educational Outreach Committee 

helped institutionalize university 

outreach in STEM. 

Teacher Resources: 

Teacher-Requested Resources 

(http://peer.tamu.edu/ 

DLC/NSF_Resources.asp) is the online 

interface through which teachers receive 

personal assistance with their math and 

science-related questions (see page 19). 

These resources allow teachers in remote 

areas of the state to request websites, 

activities, and even customized lesson 

plans which our Undergraduate Fellows 

create with the assistance of their mentoring 

Graduate Fellow. Teachers are able 

to direct our activity to better meet their 

needs both in terms of subject area and 

lesson depth. Once a response has been 

produced, it is evaluated for content by 

STEM faculty, and for public school and 

age-appropriateness by middle school 

teachers. 

Mini-modules (http://peer.tamu. 

edu/MiniMods.asp) are the PEER integrative 

(science, math, English, and 

social studies) curriculum divided into 

easy-to-use units, including downloadable 

packets of slides, activities, worksheets, 

teacher guides, and questions. 

Southwest regional NSF GK- 

12 website (http://southwestgk12. 

tamu.edu/) allows other groups (Southwest 

Region and nationwide) to upload 

lesson plans from their GK-12 program 

and search the hundreds of lesson plans. 

(Continued on page 11) 


Lessons Learned 

Larry Johnson and Bill Klemm 

Our GK-12 experiences have taught us 

many lessons in the areas of training, 

management, the use of technology, communication, 

evaluation, sharing resources, 

and sustainability. 

Selecting Effective Fellows 

Selection of the right participants is 

crucial for effective K-12 learning. We 

select Graduate Fellows on the basis of 

grades, questionnaires, and interviews, 

and we look for evidence of interest and 

experience in youth interaction 

and performance. Selection 

of teachers is not based on the 

principal’s choosing alone. We 

use feedback from two classes 

of Fellows and have instituted 

a questionnaire and formal 

interview process to select 

teachers. University faculty 

are selected according to ability 

and willingness to serve as 

lesson plan evaluators and to 

promote university support for 

sustainability. 

Correctly Training 

Fellows and Teachers 

Training is essential for both 

Fellows and K-12 teachers. 

Fellows receive one week of 

pedagogical training, journaling 

instruction, general planning 

with the teachers, and 

visitation to classrooms. We 

also hold weekly Fellows 

meetings, run by the Fellows, 

that allow them to share experiences and 

demonstrate successful activities and 

lessons. Teachers attended our summer 

Fellow training program to learn about 

their roles in the GK-12 program and to 

get acquainted with their Fellows. We 

discovered that monthly teacher meetings 

allow teachers from different school districts 

to interact and share how their Fellows 

had been effective in their schools. 


Web-based Interaction 

Project management requires weekly 

and sometimes daily attention, so effective 

web-based tracking of Fellows’ 

activities and school demographic data is 

important. Fellows benefit from monthly 

evaluations. This information is used by 

the management team to help Fellows 

who might have difficulties and to reward 

those who are remarkably effective. 

Reward systems work well for both Fellows 

and Lead Teachers. 

We patterned our online scheduling 

tracker, journaling, and data collection 

An Iola ISD student practices her strategy for a game of math bingo. 

system after that used in the University 

of Nebraska GK-12 program. This 

system collects data required by NSF for 

evaluation and progress reports. Online 

threaded discussions allow communication 

among members of the NSF GK-12 

Southwest Region. Following the Regional 

Meeting, our group developed the 

Regional website (http://southwestgk12. 

tamu.edu), to house PowerPoint presentations 

of the 10 programs present at the 

Regional Meeting and GK-12 lesson 

plans, and to provide a threaded discussion. 

We have also uploaded the AAAS 

Regional GK-12 Meeting PowerPoint 

presentations to this site. In 2005, there 

were over 2,000 pages of our site viewed 

every day of the year. 

Use of Technology 

Use of technology has enhanced effectiveness 

at all levels (data collection, 

management, evaluation, and sharing 

resources). We use web-based technology 

to procure Fellows’ applications and 

surveys to track Fellows’ activities and 

schedules through weekly journaling. 

This web-based system allows for the 

creation and editing of lesson plans and 

extends our content resources to 

teachers in geographically-isolated 

locales through our Distance 

Learning Community and 

Teacher-Requested Resources. 

It also allows threaded discussions, 

online evaluation surveys, 

and sharing of lesson plans with 

other GK-12 programs and the 

world (http://peer.tamu.edu). 

Each of the 12 Lead Teachers 

were provided with a new laptop 

and projector for use in their 

classroom during the project. 

Communication 

Communication within and 

among GK-12 groups is key to 

evaluation and to keeping the 

project on track. It is also critical 

to expand the reach of the 

project through broader impacts 

to the world. Within our GK-12 

group, we have optimized effectiveness 

of our Fellows through 

extensive online and in-person 

communication between teachers, school 

administrators, and university faculty. In 

addition, we have conducted professional 

development workshops on our PEER 

curriculum. 

Fellows’ Videos 

We discovered that it is important to 

communicate to K-12 students information 

about the Fellow as a person. We 

observed that students were motivated 

by relating to their Fellow as a person, 

and this was fostered by preparing an 

(Continued on page 15)

PEER Curriculum 

Experiences in Caldwell Middle 

School 


Teachers at Caldwell Middle School 

began using the PEER integrated curriculum 

following the spring TAKS testing. 

“It is already integrated, so students 

carry ideas from one classroom to the 

next,” said Kelly Lazo, Caldwell science 

teacher. 

The PEER curriculum involves adventure-based 

stories about middle school 

students who travel through time to solve 

mysteries. PowerPoint files and lesson 

plans cover topics in the modules, and 

include pre- and post-tests to measure 

comprehension. Last year, Caldwell used 

“Texas: 1867,” a story about the yellow 

fever epidemic in Texas after the Civil 

War. This year, they will study “Dark 

Poison,” a story about tenement housing, 

to explore the impact of cholera on the 

New York population. 

“Last year, I don’t think the kids even 

knew that those diseases existed. Then, 

when we talked about it, they realized 

people can still get smallpox in countries 

outside of the United States,” said Lazo. 

we wrote compositions and discussed 

symbolism, mood, and foreshadowing 

and then wrote a comparison essay. All 

of that covers TEKS,” said Leda Long, 

Caldwell reading teacher. 

PEER faces challenges as teachers attempt 

to reconcile its environmental 

health lessons with TEKS objectives. 

“We’re using it in May because we like 

integration, but alignment to TEKS is not 

perfect, so it’s hard to get in,” said Lazo. 

To address this, PEER hired former 

teacher Shawn Martin to review all materials 

for TEKS compliance. 

“The only other challenge I would say 

is that it’s hard for teachers to have time 

to meet and coordinate the curriculum, 

because teachers have to stay after school 

to prepare. If someone else creates a curriculum 

and you just hand it to another 

teacher, it’s hard to understand what’s 

going on,” said Long. 

PEER’s integrated curriculum is available 

online where it can be downloaded 

as a series of mini-modules. The entire 

curriculum can be ordered, free of charge 

from PEER. For more information about 

the curriculum and PEER activities, 

please visit http://peer.tamu.edu. • 

Danielle Lewis demonstrates her 

research to a middle school student 

visiting Texas A&M University. 

TeacherSpeak 

Most rewarding part of having a 

Fellow in the classroom: 

• “time in preparation saves the teacher’s 

time” 

• “Fellows develop ideas to fruition” 

• “rediscovering concepts in the classroom” 

• “getting materials” 

• “walking science encyclopedia” 

• “more activities” 

• “guest speakers” 

• “she’s [my Fellow is] a fresh face” 

“We read the story in reading class; then 

Middle school students learn biology of the respiratory system during a scientist visit. The students 

examine a horse’s tongue with attached respiratory structures. 

Areas where PEER has been 

especially useful: 

• Kids get excited about the Resident 

Scientist/Mathematician (RS/RM) coming 

to class. 

• The RS/RM makes math fun and exciting. 

• The RS/RM is always coming up with 

something new. 

• The RS/RM helps plan field trips and 

guest speakers. 

• The RS/RM helps reduce the burden of 

creating and preparing activities. 

FellowSpeak 

Tips for interacting with your 

teacher: 

• Be flexible. 

• Don’t be egotistical. The teacher already 

knows a lot. 

• Create an initial bond. Ask about the 

teacher’s life and interests. 

• Plan your meeting time in advance. 

• Treat the teacher like a colleague. 


Golden Nuggets 

Benefits to Graduate Students from Involvement in GK-12 Experiences 

Larry Johnson and Virginia Traweek 

A “golden nugget” is a reflection that 

captures the spirit of the PEER GK-12 

program. PEER collected comments 

from graduate students about their involvement 

in the program and presented 

the information at the national GK-12 

meeting. What follows is a brief summary 

of the data and collection techniques. 

PEER’s main goal is to assist middle 

school teachers in creating a fun and 

inviting atmosphere in their science and 

mathematics classrooms, where NSF 

GK-12 Graduate Fellows serve as math 

and science content resources. Each 

June, a new group of graduate students 

at Texas A&M University is trained for 

interaction in the middle school classroom. 

These students become Resident 

Scientists and Mathematicians and spend 

their time working directly with students 

and teachers in local middle schools. In 

addition to studying the benefits received 

by middle school students, PEER hopes 

to catalog the experiences of its Graduate 

Fellows. Most Graduate Fellows 

at PEER have never taught before or 

interacted with middle school students. 

By the time they have reached the end of 

their year as Resident Scientists/Mathematicians, 

many feel they have achieved 

a new level of understanding about their 

careers, their education, and their year 

in public school. PEER investigated the 

qualitative experiences of these graduate 

students and used mathematical analysis 

to help quantify their responses. Our 

goal was to understand how GK-12 experiences 

have enhanced graduate student 

skills, knowledge, and careers. 

PEER “Golden Nuggets” 

“I have done a few epidemiologicallybased 

activities with the middle school 

students. The kids had the chance to create 

their own outbreak scenario and have 

witnessed how fast a disease like yellow 

fever or malaria can spread in a population. 

The kids enjoy learning about reallife 

science.” 

“The GK-12 experience has enabled 

me to practically apply the concepts in 

my degree program. I now have a much 

deeper understanding of the concepts underpinning 

my program and their practical 

applications.” 

“Any time you teach your discipline, it 

forces you to master the material. The 

program has not only strengthened my 

basics, but it has also caused me to look 

more at the real-world approach.” 

“Being in this program has changed my 

life and has given me new goals in my 

career path. I am so happy that I have 

found a profession where I can use my 

creativity while also helping improve 

mathematical education in this country.” 

“The students have taught me more about 

myself. The GK-12 program has also 

forced me to think about science in applied 

real-life situations.” 

“Physics is a mathematically-based 


Question 

2005 PEER Graduate Fellow Survey Results 

1. Has your work in the GK-12 program strengthened your career path? Do you feel you have more 

opportunities as a result of your involvement? 

2. Do you feel that your experience in the GK-12 program has contributed to your knowledge or understanding 

of your discipline? Has it widened your view of how your discipline fits with the scientific/ 

mathematic community? 

Percent 

Agreement 

100 

3. Have you integrated your STEM knowledge into the K-12 classroom? 90 

4. Have you presented any of your research or research techniques in your classrooms? 70 

5. Has an advisor, professor or colleague noted that your presentation/teaching style has improved? 70 

6. Have you learned a general strategy or general information that applied to your specific research 

40 

problem? 

7. Have you had a meaningful experience(s) in the public school classroom? 90 

8. Has the GK-12 program made you a more complete scientist or mathematician or contributed to your 100 

personal development? 

9. Did you have positive benefits or effects from participation in this GK-12 program? 100 

“...the past nine months have been a series of 

continually rewarding experiences.” 


90

(Golden Nuggets, cont’d from page 8) 

discipline that ties with engineering. The 

mathematics can be made fairly simple 

for a middle school student. I have 

integrated my STEM knowledge into the 

classroom where the students pretend to 

invest in the stock market and then spend 

the year tracking their stocks.” 

“I will definitely participate in outreach 

in my community. There are disadvantaged 

students everywhere. It is our responsibility 

to help them as we are able.” 

“When asked on a job interview ‘What 

have I been doing for humanity other 

than going to class and being a graduate 

student?’, my GK-12 involvement gave 

me something to say.” • 

Middle school students examine a pig lung to demonstrate the effects of smoking during a scientist 

visit to their school. Students also learn about toxicology, anthrax, and a variety of other environmental 

health science topics. 

“The program has opened my eyes to 

the diversity of our public schools.” 

Snook’s Science Bowl Victory 

How Two Graduate Fellows Helped a Small School Win Big 


When asked about competing in the Sebesta of the mandatory practices. 

Science Bowl, Ricky Ramirez said, “It 

was something that was completely fun.” 

Ramirez, along with eight other students 

from Snook Secondary, a school of about 

150 students, competed in the Science 

Bowl and nearly won state. 

The little team from Snook had tough 

competition. Snook had never been to a 

Science Bowl nor did they have experienced 

Science Bowl coaches. The students 

practiced twice a week after school, 

honing their math and science skills. 

PEER Graduate Fellows Erin Anitsakis 

(Oceanography) and Michael Karka 

(Biomechanical Engineering) hosted the 

practices and used their science and math 

expertise to guide the team. 

Students met with Anitsakis and Karka, 

who focused on math and science using 

hands-on activities to reinforce concepts. 

In one such activity, Karka led the class 

in a miniature competition. “We got fishing 

lures and used the weight to create an 

elevator,” said Ramirez. The classroom 

elevator contest winners visited Texas 

A&M University, where Karka demonstrated 

laser experiments. 

In the Science Bowl, Snook Secondary 

went 3-1 in the preliminary round and 

lost a tie-breaker in the playoffs. Students 

and teachers were amazed that the 

previously unknown Snook team was 

almost unstoppable. The tournament 


“They test through 8th grade, and a lot of 

our Science Bowl kids were 6th grade. 

They were being exposed to higher level 

mathematics,” said Laura Sebesta, Snook 

math teacher. 

To prepare, the Fellows created a practice 

schedule that emphasized student 

responsibility. “[The students] took it 

upon themselves to make sure they were 

there all the time. Nobody had to be reminded,” 

said Snook math teacher Laura 

Graduate Fellows Erin Anitsakis of Oceanography and Michael Karka of Biomechanical Engineering 

pose with the Snook Science Bowl team at the competition. The students, who had 

never before competed in Science Bowl, made it to the semifinal round of competition. 


(Science Bowl, cont’d from page 9) 

director told Karka that he was impressed 

with Snook making it so far in their first 

year of competition. “I overheard some 

kids asking their teacher where Snook 

was,” said Karka. “They were shocked 

that our kids were so good.” 

Now that Science Bowl is over, Snook is 

already planning for next year’s competition. 

“It felt good that all that hard work 

finally paid off. If we have it next year, 

I’ll do it again,” said Cullen Hairell, team 

captain. 

As for the impact the competition has 

had in the lives of the students, Nicky 

Wiggins said, “It makes me want to go 

further into my career, not just get a 

bachelor’s degree, but go on and get my 

master’s and a doctorate.” • 

Teacher Training 

Undergraduate Fellows, staff, and faculty, in addition to the GK-12 Graduate Fellows, 

also interacted with teachers throughout the state via direct contact at teacher professional 

workshops or via distance learning connections. Rural teachers throughout the state 

reported a positive impact as a result of the PEER integrative curriculum and technology 

training for themselves, their fellow 

teachers, and their students. 

A group of 166 teachers from 

9 workshops throughout Texas 

scored significantly higher on 

post-tests than pre-tests on content 

material for all four subject areas 

(math, science, social studies, 

English) and toxicology. These 

teachers shared the curricular 

materials with 423 teachers and 

7,071 students. Additionally, 49% 

of teachers ranked themselves as 

having improved their PowerPoint 

skills following the workshops. 

Dr. James Kracht addresses teachers at a PEER 

professional development workshop. 

PEER and GK-12 Improve Middle School Teaching 

Diana Mowen 

After a full school year working with a 

GK-12 Graduate Fellow in their classrooms, 

teachers acknowledged experiencing 

many positive changes. One of 

the most successful objectives of the NSF 

GK-12 program was to increase Lead 

Teachers’ content knowledge through 

interaction with the GK-12 Graduate 

Fellows. 

Teachers reported increasing their use of 

technology in the classroom as a result 

of their interaction with Graduate Fellows. 

At the beginning of the school 

year, the GK-12 Graduate Fellows 

conducted activities with students using 

new technologies (PowerPoint presentations, 

computer research activities, and 

equipment commonly used in scientific 

research). As these types of technologies 

became more commonplace in the 

classrooms (the GK-12 program provided 

a laptop computer and digital projector to 

each Lead Teacher), teachers developed 

greater confidence using them and began 

incorporating them into class lessons 

even when the GK-12 Graduate Fellows 

were not present. Following teacher participation 

in the program, students will 

continue to benefit from the teachers’ use 

of up-to-date technologies. 


These changes have contributed to an 

increase in job satisfaction among participating 

teachers. Even though the Resident 

Scientists and Mathematicians will 

leave the classrooms to pursue STEM 

careers, the teachers will have a greater 

knowledge of their discipline, greater 

competence using and staying abreast 

of new technologies, and a renewed 

appreciation of how fulfilling teaching 

young people can be. These changes will 

continue to affect these teachers and their 

students for many years. 

K-12 Student Interest in 

STEM: 

Almost 10% of students in participating 

classrooms changed their attitude of 

STEM from negative to positive over the 

course of one year. The major reasons 

for changes included: NSF Graduate 

Fellows being present in the classroom, 

and K-12 students wanting to go to college, 

liking subject material, thinking 

they were smart enough, and having a 

positive self-image. This is a significant 

finding given that most research shows 

student interest in STEM has been shown 

decrease after the sixth grade. 

Improved Impact by GK-12 

Fellows: 

Teachers evaluated the performance and 

impact of the Graduate GK-12 Fellows in 

their classrooms at both the middle and 

end of the 2004-2005 school year. As the 

year progressed, teachers saw improvement 

in the quality of activity preparation 

by the Resident Scientists/Mathematicians, 

as well as greater appropriateness 

of activity objectives. 

The teachers reported increased effectiveness 

of their own relationships with 

other teachers and parents. The work 

of the GK-12 Graduate Fellows in the 

classroom also resulted in greater student 

involvement in class activities. Teachers 

expressed approval of the increased 

ability of GK-12 Graduate Fellows to 

develop the interest of students while 

planning and implementing activities in 

the classroom. 

GK-12 Graduate Fellows improved their 

ability to conduct interesting and engaging 

activities, which resulted in classroom 

order being maintained. •

A GK-12 Experience in Mathematics 

G. Donald Allen 

The GK-12 program seeks to involve 

public schools, graduate students majoring 

in STEM areas, and faculty in highquality 

universities. It is nothing less 

than a program with hundreds of variations 

and thousands of possibilities. This 

complexity is tremendously attractive to 

academics like me who have devoted a 

career to mathematics research. 

What I do is listen and learn about the 

issues affecting schools. In my personal 

outreach to the schools, I interface with 

the teachers through various forms of 

professional development. What I have 

learned is that there is uncertainty among 

teachers about the conflicts between 

the content they are asked to teach, the 

pedagogy they are asked to apply, and 

the high-stakes testing that is used to 

measure their performance. Through 

my involvement in the GK-12 program, 

I find the pure goal of teaching children 

refreshing. It is remarkable that STEM 

graduate students are fully involved in 

the process of middle school student 

learning, since this is almost impossible 

in other environs. It is my great pleasure 

to help as we explore STEM teaching 

and learning. 

This GK-12 program is one of my most 

rewarding professional endeavors. It has 

shown me numerous research problems 

in the field of mathematics education 

which need desperate attention to help 

resolve critical problems in STEM learn- 

ing. The most important question of the 

day is: “Why do children get turned off 

to mathematics (and science) at such an 

early age?” Is it the students? Is it the 

teachers? Is it the subject? The answer 

is not clear. Middle schools are the proving 

ground, for this is where it happens. 

It has been very rewarding to see the 

fierce dedication of our teachers and to 

see and measure their successes. We 

need to determine how and why the confluence 

of graduate students with teachers 

contributes to such successes in the classroom. 

This remarkable symbiosis seems 

to be common among GK-12 programs 

nationally. Also, it is rewarding to serve 

as a mathematics 

faculty 

reviewer of 

the Teacher- 

Requested 

Resources that 

broaden the 

reach of the 

university to 

rural schools. 

Another 

reward is that 

I’ve met a 

number of professional 

academics, 

graduate 

students, 

and teachers 

all with the 

same goal of 

improving STEM education everywhere. 

This has led to my work on other STEMtype 

projects. Most of my work has been 

with teachers at the high school level and 

most have been from rural areas where 

the needs are most acute. Through this 

GK-12 program, I see a very committed 

core of professors, graduate students, 

and teachers trying to raise the bar of 

achievement of their students. Finally, 

I am involved in other STEM projects 

with teachers and students across the 

state, which may not have been possible 

without this GK-12 project. • 

Don Allen, professor in the Mathematics 

Department, has developed 

online mathematics courses and 

professional development workshops. 

Dr. G. Donald Allen with a group of middle school math club students visiting 

Texas A&M University. 

(Project Products, cont’d from page 5) 

Regional threaded 

discussion enables Fellows, 

teachers, administrators, and 

evaluators to select the specific type of 

communication in which they want to 

participate. 

Online introductory video 

streaming (http://peer.tamu.edu/ 

interviews.shtml) helps schools gain 

information about and access to graduate 

students in university math and science. 

One lesson learned by comparing the 

Fellows’ streaming videos addressing 

roughly the same questions as asked 

of our faculty and answered in the 

virtual interviews (http://peer.tamu. 

edu/interviews.shtml) is that Fellows 

did not drive home an underlying 

faculty theme, namely that stamina 

and maintaining focus are important 

in preparing for and meeting academic 

goals. Perhaps the Fellows had not 

yet become hardened (matured) by 

years of seeing the wasted talent of 

many undergraduates or perhaps they 

were correct in using their time on 

stimulating comments. • 

Erin Anitsakis of Oceanography discusses her research 

in her pre-classroom introductory video. 


The Death of “Drill and Kill” 

School Administrators Speak Out about Facilitating Hands-On Learning 


Though PEER graduate students have Michael Karka, Texas A&M University 

been active in approximately three dozen biomechanical engineering major, in her 

classrooms since the program began, the classroom. “Michael has taken things 

behind-the-scenes work has largely gone that I’ve had in my head and never had 

unnoticed. In addition to needing willing a chance to do and seen how the kids 

teachers, PEER Graduate Fellows have responded to them. We’re able to do a lot 

also needed the help of middle school administrative 

staff to approve projects and 

more with the kids,” she said. 

provide support as teachers integrate new 

teaching techniques into the classroom. 

Robert Reyes, middle school principal 

for Snook ISD, has overseen three different 

PEER Fellows as they completed 

their year of classroom assistance. “I 

know [Ms. Donald] had a couple of 

students that were maybe a little more 

‘at-risk,’ but when they were doing 

activities [with their Resident Scientist], 

they got along just like everybody else,” 

said Reyes. 

PEER’s involvement in Snook schools 

began by word of mouth, first with a 

summer tutoring session and then with 

the placement of GK-12 Graduate Fellows 

in the classroom. Gerri Maxwell, 

Snook curriculum coordinator, noticed a 

difference in the students. “We were able 

to have pretty good attendance all summer, 

which tells me that it was effective 

at least on that measure,” said Maxwell. 

After the initial summer tutoring, PEER 

placed a graduate student in the middle 

school math class during the 2004-2005 

school year. During the 2005-2006 

school year, two new graduate students 

were placed in the middle school math 

and science classrooms. 

“You can’t have one hundred percent 

project-based instruction; you can’t have 

one hundred percent drill and kill. Somewhere 

there’s got to be a happy medium,” 

said Maxwell. The happy medium, it 

seems, is combining the time and expertise 

of the PEER graduate students with 

the curriculum knowledge of the teachers. 

Teacher Laura Sebesta spent a year with 


PEER involvement has gone beyond simply 

assisting teachers. It has sometimes 

been responsible for tremendous changes 

in classroom techniques. “I know in one 

case that there’s a night and day difference 

in the way that one of our teachers 

does instruction because of having PEER 

in her classroom, so I am 

happy about that,” said 

Maxwell. 

Most administrators felt 

that allowing the teacher 

freedom to change his or 

her teaching style was most 

important. “I don’t really 

do much. I just let them 

run with whatever they 

need to do,” said Reyes. 

“If you really want to 

maximize the effectiveness 

of having Fellows in the 

school, I think you should 

have meetings with the Fellows, 

the administrators, 

with the teachers involved 

and with the people at the 

university,” said Maxwell. 

TeacherSpeak 

One of the benefits of having a college 

student in the classroom is the connection 

students make between their education 

and their future. “When they see their 

Fellow, they are developing an interest 

in things they could do in college,” said 

Reyes. 

“When I have gone in and observed 

classes where students were doing handson 

activities, the students are always 

engaged. I think they enjoy that instruction,” 

said Maxwell. • 

Danielle Lewis, NSF Graduate Fellow, helps demonstrate a 

science experiment at the Southwest Regional GK-12 Meeting. 

Having a GK-12 Graduate Fellow that we called “Resident Scientist” in my classroom 

for the past two years has been incredible. By far the best part was being able to bounce 

ideas off someone who was not a “teacher” in the traditional sense, but more of a “scientist.” 

All too often, classroom teachers get bogged down with the real world and lose 

some of the excitement of real science. Having GK-12 Fellows for the last two years 

greatly improved my teaching. I learned so much (especially in the field of genetics!) 

and I found that by working with them, I was able to think outside the box and come up 

with new ways to teach things. They also reminded me of the power of scientific inquiry, 

something that I have always used but I now use much more often! 

Jan Fechhelm 

Cypress Grove Intermediate 

College Station, Texas

Dr. Bill, Memory Medic 

Bill Klemm 

Dr. Bill, “Memory Medic,” is a PEER 

Co-PI who specializes in helping students 

remember their school lessons. 

When Dr. Bill was in the 7th grade, he 

finally got interested in making good 

grades. But, Bill had other interests too, 

so he had to find ways to be efficient at 

school work. That meant learning how to 

remember school lessons without having 

to read them over and 

over. Besides, “drill and 

kill” was boring. Bill 

learned ways to get most 

of it right the first time, 

usually while he was still 

in class. Today, Dr. Bill’s 

research has helped scientists 

understand how the 

brain works, specifically 

memory. He has developed 

these tips to improve 

learning efficiency: 

Register the information 

in the first place. 

Most people find it hard 

to remember names 

because the names never 

registered in the first 

place. The key is to really 

pay attention when 

you are confronted with 

new information that you 

are supposed to remember. 

To do that, it helps to think 

the information is very important (even 

if you don’t believe that it is). People 

pay attention to things that they think 

are important and paying attention helps 

Dr. Bill Klemm in his memory 

medic jacket. 

register the information, increasing the 

odds that it will be remembered. 

Relate new information in ways that 

help give it meaning. For example, you 

can relate it to things you have already 

learned. Associate items to be remembered 

in groups, and in those groups 

include things you already know. The 

best associations are 

visual images. Invent 

weird mental pictures to 

represent what you are 

trying to remember, and 

include in the picture 

an image of things 

you already know. It 

even helps to have an 

animated video clip 

in your “mind’s eye.” 

For example, suppose 

you want to remember 

“chromosomes, genes, 

DNA, nucleotide bases,” 

and the scientists who 

figured out how DNA 

was made: “Watson 

and Crick.” Create in 

your mind a picture of 

a baseball field, seeing 

the bases (nucleotide 

bases). Ask yourself 

“What’s on (Watson) 

first base?” See a car, 

with huge chrome 

(chromosome) bumpers all around it. The 

driver of the car has a crick (Crick) in his 

neck that makes him lean out the window 

the whole time he is driving around the 

bases, and he stops briefly on each base. 

Rehearse what you are trying to 

remember while it is still fresh in your 

mind. At this point, the information is 

on your mental “scratch pad,” which is 

easily erased by new information. Don’t 

let yourself be distracted until you have 

rehearsed your mental pictures several 

times. While rehearsing, think of all the 

details that go with what you are trying 

to remember. These details serve as clues 

that help you remember it in the first 

place and make it easier to retrieve later. 

Rehearse briefly several times during the 

first day and the next day. Doing this 

ensures you remember the information, 

therefore decreasing study time. 

Retrieve as much of the information 

as you can. Remembering some 

parts will serve as clues for recalling the 

rest. If you are under pressure, as in a 

test, don’t panic. Remind yourself that 

your brain has this information and that 

you can get it out if you just think of the 

clues that you remembered right away. 

Don’t bang yourself on the head saying, 

“Think, think, think!” Relax, trust your 

brain to do its job, and chances of correct 

recall will improve. Be patient. Think 

about other things temporarily when you 

are stumped. • 

Bill Klemm is Co-PI of the PEER 

project and has spent most of his 

career researching memory. Visit 

thankyoubrain.com for memory 

tips and a blog on current topics 

in neuroscience, or read Dr. Bill’s 

book, “Thank You Brain For All You 

Remember: What You Forgot Was My 

Fault.” 

Comments about 

Bill Klemm’s 

“Thank You Brain” 

I recommend this book for the student, 

the professional, and the senior citizen. 

This is a book that everyone wanting 

to look “smart,” feel “smart,” and be 

“smart” can read and enjoy. The book 

presents technical information ... and 

then rephrases it in easy to understand 

terms for the lay reader. Key ideas at 

the end of each chapter summarize the 

salient points. The author has interpreted 

and reviewed, in plain language, the detailed 

tests and results of years of scientific 

experiments. 

- reader review, posted on Amazon.com 

Each chapter’s theme in this scholarly 

work is supported through charts, graphs, 

research, lists of tips and citations, 

but not to worry, Dr. Klemm writes in 

laymen’s terms and his conversational 

tone speaks directly to readers. Highly 

recommended. 

- Lavern Hall, editor, “A Glass Full of 

Tears: Dementia Day-by-Day” 

[Whatever your memory problem, ] 

Klemm (a.k.a. the “Memory Medic”) has 

a solution for you. He has recorded his 

findings in this helpful book that includes 

more than 150 ways to improve memory 

for people of all ages and in all stages of 

life. 

- “Auburn Alumni Magazine” 


Scientists’ Visits 


Thirty-five thousand middle school students 

and over 1,200 teachers in central 

Texas and throughout the United States 

can now say they feel differently about 

science following interactive presentations 

given by Texas A&M University 

professors. In addition to sending graduate 

students into classrooms for direct 

contact with middle school students, 

several professors travel to schools with 

specimens and activities to stimulate 

student interest in the sciences. 

Dr. Larry Johnson, Principal Investigator 

for PEER, travels to middle schools 

across the country with a collection of 

plasticized animal lungs and torsos to explain 

the dangers of smoking. Students 

test their lung capacity and are shown 

human tissue samples of a smoker’s and 

a non-smoker’s lungs. 

He starts by asking students, “What is the 

function of the respiratory system?” Students 

ultimately state that it functions in 

getting O 2 

into the body and discharging 

CO 2 

. Dr. Johnson explains this function 

called “gas exchange.” Like plumbing 

in a school or house, the lungs have 

special structures that get air carrying O 2 

into air sacs where it can be exchanged 

into the blood vessels in the walls of the 

sacs. The plumbing inside the body, Dr. 

Johnson continues, is called anatomy, 

and the respiratory tract has two portions 

to its anatomy. The conducting portion 

provides the conduit to the outside and 

cleans, warms, and humidifies air as it 

goes into the air sacs of the respiratory 

portion where gases (O 2 

and CO 2 

) are 

exchanged. Carbon dioxide is discharged 

by exhaling. Students are amazed that 

the surface area of the air sacs is the size 

of a tennis court due to elaborate branching 

of the conducting portion. Students 

learn that inhalation (into the respiratory 

system) is one of four routes of exposure 

to environmental toxicants. The other 

three are ingestion (route by which poison 

killed Romeo), absorption (through 

the skin or eyes), and injection (like 

mosquitoes that transmit West Nile virus 

and agents causing malaria). 


Students learn that most 

diseases are an over- or 

under-expression of a normal 

function. The constriction 

of bronchioles 

(airways of the conducting 

portion) in response to an 

inhaled stimulus is normal, 

but with asthma, the 

airway constricts air flow 

when it should not. 

Students learn that the 

thickness of the barrier in 

the lung air sac between 

air and blood is much 

less than the thickness of 

a single red blood cell. 

Hence, environmental 

materials that enter by 

inhalation are very close 

to your blood. What 

you breathe influences 

your health. Students learn that smoking 

damages ciliated cells of the conducting 

portion which move mucus out. It is 

the loss of these cells that gives smokers 

the “smoker’s cough.” Students see that 

smoking fills the garbage traps of the 

body (macrophages in the airway in this 

case) and turns the lungs black. 

Students learn that smoking can cause 

emphysema (breakdown of the sac walls 

allowing too much air in the lungs and 

reduction in surface area of the respiratory 

portion). Other diseases discussed 

include pneumonia (swollen sac walls, 

edema, and increased thickness of the sac 

barrier through which oxygen and carbon 

dioxide must pass for gas exchange) and 

lung cancer. Students also learn about 

the excitement of discovery, scientific 

travel, opportunities, and satisfaction of 

careers in science. 

Dr. Johnson’s approach is to try to 

facilitate a knowledge base that leads to 

greater self-esteem and self-awareness 

when choosing careers. “I get to stimulate 

their curiosity,” Johnson says, “and 

that is very gratifying.” 

Thank you note from a second grader. 

“The students were able to view actual 

specimens, and Dr. Johnson elaborated 

on material that they had learned in 

class,” said Kelly Lazo, science teacher 

at Caldwell Middle School. “Throughout 

the year, when we discuss similar topics, 

they bring up his visits and things they 

learned from him.” 

Another subject on which Dr. Johnson 

speaks is toxicology, the study of poisons. 

Most students are surprised to 

learn that almost any substance can be 

poisonous with the correct dose, even 

salt, sugar, and water. 

The premise behind these and other scientists’ 

visits is that most middle school 

students think science is boring or too 

difficult. PEER strives to spark interest 

among youth by encouraging inquirybased 

learning. “I start every visit with 

simple questions that the kids can answer 

easily. If they feel like they understand 

early in my lesson, they tend to be more 

involved later on. Then I try to challenge 

them a little. When I talk about toxicology, 

I ask them why one piece of candy 

is fine, but a full bag makes them sick. 

(Continued on page 15)

(Scientists’ Visits, cont’d from page 14) 

They all know that excess sugar consumption 

causes an upset stomach, but 

often do not realize that they are verbalizing 

a fundamental concept in toxicology, 

namely ‘dose makes the poison’ and not 

the sugar itself.” 

“Middle school students are in special 

need of guidance toward science careers,” 

Johnson said. “This age group 

is sort of a forgotten group. The least 

amount of attention is placed on middle 

school, even though it is a prime developmental 

period. This is the time they 

establish interest in careers. We want to 

catch them before they decide that a science 

career is not important.” 

Ninety-three percent of students report 

learning something from the presentations. 

Seventy-nine percent plan to share 

what they have learned with others. “The 

most important piece of data,” Johnson 

said, “is the fact that the students felt the 

same about the presentations regardless 

of where I went and to whom I spoke. 

This means that any scientist, anywhere, 

can do this and get the same results.” 

Students have written a variety of comments 

on the evaluations, ranging from, 

“I didn’t like the dog because it was 

dead” (a reference to one of the plasticized 

specimens Dr. Johnson carries 

on his visits) to “I learned all about 

how the lungs worked, which I did not 

really understand before the presentation.” 

Another student thought the most 

interesting part of the presentation was, 

“that the cause of hiccups is because 

your diaphragm is just having a contraction 

that you can’t stop.” One student 

even responded, “Texas A&M University 

is probably my future college, but all I 

thought of A&M was its sports. Now I 

see that their science program has advanced 

technology and is worth looking 

into.” 

Creating contacts with teachers is an important 

aspect of Johnson’s involvement. 

“Every year, we send out about 4,000 

letters asking teachers if they want a scientist 

to visit their classroom,” Johnson 

said. “When I get invited, I try to speak 

to the students on their own level and try 

to be funny. They want to know what I 

do and where I have traveled, but they 

also want to have fun during the lecture.” 

“Although not all will go to college,” 

said Johnson, “the goal is to make sure 

that all are aware of their own potential. 

We are reinforcing teachers as they 

encourage students to make informed 

decisions.” • 

Pre-med GK-12 Undergraduate Fellow Varun Chowdhary illustrates organs and systems in a dog to 

middle school students during a summer camp. 

StudentSpeak 

Things you liked about having the 

Fellow in the room: 

• “having fun but still learning” 

• “Friday afternoon activities” 

• “having someone other than the teacher 

in the room” 

• “playing math games” 

• “joking with my Fellow” 

Things your Fellow taught you: 

• adding and subtracting exponents 

• FOIL method for binomial multiplication 

• Pythagorean Theorem 

• calculating surface area 

• dividing fractions by whole numbers 

• multiplying and dividing fractions 

• how to use weights to create an elevator 

(Lessons Learned, cont..d from page 6) 

introductory video about each Fellow. 

Fellows also participated in relevant outof-class 

activities (such as science/math 

contests, science clubs, and field trips to 

the university and the Fellow’s lab). 

Evaluation/Sustainability 

Evaluation has been useful for showing 

that the GK-12 program has had a 

significant impact on Fellows, teachers, 

and K-12 students. We have added a new 

committee, the Educational Outreach 

Institutionalization Committee, and an 

institutionalization objective to the proposed 

GK-12 continuation application. 

The PI and two of our Co-PIs (Klemm 

and Allen) have formed a university-wide 

K-12 Educational Outreach committee 

under the auspices of the local chapter 

of Sigma Xi. PEER will attempt to 

revise the university’s graduate training 

infrastructure to include K-12 outreach 

as a routine part of graduate education 

for interested students. Institutionalization 

of the GK-12 concept will include 

the development of graduate science and 

math outreach courses, incorporation of 

projects of other faculty needing “broader 

impacts,” and alteration of the graduate 

assistantship finances to include K-12 

outreach. • 


Southwest Regional GK-12 

Meeting, October 2005 

Larry Johnson 

The first Southwest Regional NSF 

GK-12 meeting was organized and 

hosted by PEER in the College of 

Veterinary Medicine and Biomedical 

Sciences at Texas A&M University. 

The expected outcomes of the conference 

were to: 

1) Establish collaborations through 

the immediate sharing of 

resources and subsequently through 

an online threaded discussion 

forum; 

2) Share ideas to enhance 

effectiveness of the program, 

including impact on participants, 

establishment of links between 

higher education and public 

schools, and sustainability and 

institutionalization of GK-12 

training of graduate students; and 

3) Provide a framework for future 

collaboration opportunities among 

regional GK-12 groups. 

Ten GK-12 groups from four states 

prepared a 12-minute presentation that 

covered their program successes. 

Each GK-12 Fellow who attended 

the meeting was required to prepare a 

poster to present at a lunch-time poster 

session. Teachers and managers were 

also invited to present. Posters prepared 

by Fellows detailed findings 

regarding the overall effectiveness or 

impact of the program, as well as an 

involved activity or series of activities 

conducted in the Fellow’s school, 

an unusual finding of PEER’s involvement 

in public schools, or other 

aspects of PEER or interactions with 

K-12 students or teachers. 

Each attending GK-12 group created 

a packet of five outstanding lesson 

plans that reflected original, polished 

activities that had been tested in the 

classroom. These were shared with 

other GK-12 groups during the “Birds 

of a Feather” session. 


At the opening reception, Dr. Fuller 

Bazer, Executive Associate Vice 

President for Research at Texas A&M, 

discussed research enterprises of Texas 

A&M University, and Sonia Ortega 

provided comments for NSF about the 

value of regional NSF GK-12 meetings. 

The welcome was delivered by 

Evelyn Tiffany-Castiglioni, Associate 

Dean of Undergraduate Programs in 

the College of Veterinary Medicine. 

Karen Watson, Dean of Faculty at 

Texas A&M University, spoke on “Recruitment 

of Women and Minorities in 

STEM.” During lunch, posters were 

displayed in the hallway for participants 

to view. 

Special topics covered 

during the meeting were: 

Developing Lasting Networks and 

Opportunities for Collaboration, Birds 

of a Feather Breakout Sessions (Math 

Fellows/Teachers: Science Fellows/ 

Teachers, PIs, Evaluators, and Managers), 

Sustainability, Birds of a Feather 

Reporting, hands-on activities (involving 

geology, GPS, and general experimentation), 

and closing remarks by 

Sonia Ortega. 

Outcomes of the meeting: 

It was noted at these sessions that a 

means for collaboration and sharing 

lesson plans was needed. As a result 

of the meeting, a Southwest Regional 

website was produced by our PEER 

GK-12 group (http://southwestgk12. 

tamu.edu). The site has details of the 

meeting, including session notes, a 

mechanism for uploading and sharing 

lesson plans among regional and 

national GK-12 groups, and a threaded 

discussion for various groups in the 

GK-12 programs (e.g., teachers, Fellows, 

PIs, and administrators). • 

Sonia Ortega, NSF GK-12 Program Director, gets the 

Southwest Regional GK-12 meeting off the ground! 

Mechanical Engineering GK-12 Graduate Fellow Ryan 

Pedrigi displays his “Fun with Physics” poster. 

Lead Teacher Pamela Donald shows off her class activities 

with the GK-12 Project. 

Teacher Andrew Lyon demonstrates sediments to students 

and parents at the regional meeting.

The Making of a “Mathemagician” 

Marta Kobiela 

I remember distinctly the Christmas of 

1992. I was eleven years old and dreaming 

of presents desired by every elevenyear-old 

girl: dresses, dolls, and the list 

goes on. At the Christmas tree, I found a 

different surprise. My dad handed me a 

package with an air of accomplishment, 

as if he had chosen the perfect gift. I 

opened it to find a book: “Mathemagics” 

by Arthur Benjamin and Michael Brant 

Shermer. I realized that perhaps I was 

not meant for the cool life of hip clothes 

and neat gadgets. I gave in and read a 

chapter, but only a chapter. 

For many years the book stood on the 

shelf, a distant part of my life. It was 

not until I was in college, studying math, 

that I experienced a second encounter 

with “mathemagic.” During a summer 

research program in California, one 

of my mentor professors, Joe Chavez, 

dazzled us with his mathemagic routine. 

This routine had been used for years at 

birthday parties, in classes, and for family 

and friends. 

It was not until a year later that I became 

hooked. At a math conference, amid the 

equations and proofs, I saw the author 

of my book, Arthur Benjamin, give a 

“mathemagic” performance. It was 

mesmerizing, funny, quizzical, anything, 

and everything. From then on, I knew 

my future. 

Being an amateur, I had to research to 

find good tricks. After reading books, 

searching the Internet, and modifying 

ideas, I came up with a small, but not 

too shabby, collection of acts. My most 

common act relies on the power of candy 

to entice audiences. Using simple candy 

algebra, participants disentangle “secret” 

number puzzles. Skittles represent 

ones and a Starburst represents a secret 

number. The participants can visualize 

the problem using the candy. I might ask 

the audience to do the following: Pick 

a secret number (represented by one 

Starburst). Add seven (Skittles) to the 

number. Multiply your answer by two 

(double Skittles and Starbust). Subtract 

six (Skittles) from your new answer. 

Divide this by two (Take away half of the 

candies.). Subtract your secret number 

(the last Starburst). 

Magically (or so it seems), each person 

always ends the series of steps with an 

answer of four, no matter what the secret 

number was. A regular magician would 

selfishly leave the audience to admire 

with awe, but as a “mathemagician,” I 

feel the true beauty of the process is in 

understanding why it worked. 

Another fun activity involves the amazing 

properties of dice. With my back 

turned, I ask for a volunteer 

to stack three dice, 

one on top of another. I 

also ask the volunteer, 

with the help of the 

audience, to add together 

the bottom face of the 

lowest die to the four 

faces that are touching. 

After turning around and 

glancing at the top of 

the stack, I can tell the 

participant what his or 

her sum was. 

Simply enough, the 

opposite sides of a die 

always add up to seven. 

By subtracting the value 

on top of the stack from 

twenty-one, I can always 

find the correct sum. 

Being an amateur is not easy. My costume 

is poor, my salary is nonexistent, 

and I never get asked to perform at birthday 

parties or write books. But seeing 

the faces of the students makes it worthwhile. 

I know they are thinking, if even 

momentarily, that math is cool. That is 

the best reward ever. • 

Marta Kobiela served as a GK-12 

Graduate Fellow for the 2004-2005 

and 2005-2006 school years. She is 

now pursuing her doctorate at Vanderbilt 

University. 

Value of Scientists in Public Schools 

Scientists gain much benefit from interacting with teachers and students in secondary 

education. First, for a scientist to discuss their research with students in Grades 6-12, they 

must understand it! Knowledge of science in its most basic form is critical to having a 

meaningful interaction with young students. It is a beneficial experience for any scientist 

to gain such a detailed understanding of their work. In addition, breaking down science 

into a form that can be understood by young students may allow a researcher to identify 

needed improvements that previously were not obvious. Secondly, while we all want to 

think our research is important, igniting the lamp of interest in a young student may be our 

most important contribution to science. Certainly, our science and results contribute to a 

better understanding of our area of interest. However, how can one measure the contribution 

of the teacher who motivated Albert Einstein or Jonas Salk? 

-K.C. Donnelly, Professor and Head of Environmental and Occupational Health 

Texas A&M University, Health Science Center 


First-Year Classroom Improvement 

Shannon Degenhart 

Methodology 

At the beginning of the school year, NSF 

Fellows were assigned to Lead Teachers 

whose classrooms were to be their primary 

focus. The Fellows were expected to 

spend at least 10 hours per week interacting 

in middle school classrooms, serving 

as content specialists, and promoting 

inquiry-based activities. Pre-surveys 

were administered to all students prior 

to Fellows’ involvement. During the 

course of the school year, Fellows were 

expected to reach out to other classroom 

teachers in the school and interact in their 

classrooms as well. By the end of the 

school year, Fellows were expected to 

spend approximately 60% of their time 

in the Lead Teachers’ classrooms and 

40% in the classrooms of other teachers 

within the school system. At the end of 

the school year, post-NSF surveys were 

administered to students in both Lead and 

other teachers’ classrooms. 

Middle school student data (n = 1,145) 

were collected from 12 Lead Teachers 

and 12 other teachers representing 10 

schools in a 40-mile radius of the university. 

Quantitative data were analyzed by 

univariate and multivariate analysis using 

the Statistical Package for the Social 

Sciences (SPSS). Classroom inquiry was 

measured using the criterion-referenced 

Reformed Teaching Observation Protocol 

(RTOP). RTOP quantitative scores are 

derived from five elements: 1) lesson design 

and implementation, 2) propositional 

knowledge, 3) procedural knowledge, 4) 

student/student relationships, and 5) student/teacher 

relationships. Each element 

consists of five items that are rated from 

0 (never occurred) to 4 (very descriptive). 

Overall scores range from 0 to 100 

(Sawada et al., 2002). 

Members of the evaluation team observed 

each Fellow in the classroom multiple 

times. The evaluator only observed, 

scoring the classroom environment after 

the class period was completely finished. 

Cronbach’s alpha coefficient was used 

to determine interrater reliability (.918) 

between evaluators. 


Independent sample t-tests were used 

to determine if significant differences 

existed between mean RTOP scores by 

semester or time of day. Analysis of Variance 

were performed in SPSS to determine 

if significant differences between 

mean RTOP scores were influenced by 

NSF Fellow, teacher, grade level, subject, 

observer, location, or announced observations. 

Results 

Pamela Donald meets with her NSF GK-12 Graduate 

Fellow, Laura Oehler, to discuss lesson plans. 

Quantitative data were analyzed from 

the matched responses of 1,145 middle 

school students. Of the 1,145 students, 

471(41.1%) were 6th graders, 

290 (25.6%) were 7th graders, and 371 

(32.8%) were 8th graders. In addition, 

517 (45.2%) students were male, 560 

(48.9%) were female, and 65 (5.7%) did 

not declare their gender. Other teachers’ 

classrooms accounted for 418 (36.5%) 

students with 727 (63.5%) students in 

Lead Teachers’ classrooms. 

Multivariate analysis indicated that when 

the teacher and Fellow were present in 

the classroom, grade level and the Fellow 

had a significant effect (p < 0.05) on the 

rate at which middle school students’ 

interests and beliefs in STEM subjects 

changed. The teacher did not have a 

significant effect (p

students’ self-efficacy in those subjects. 

Self-efficacy is defined by Pajares and 

Miller (1994) as “a context-specific assessment 

of competence to perform a 

specific task, a judgment of one’s capabilities 

to execute specific behaviors in 

specific situations” (p. 194). Bandura 

(1986) linked self-efficacy to a student’s 

motivation and achievement in a particular 

subject. The potential of NSF Graduate 

Fellows to build positive STEMrelated 

self-efficacy is a particularly 

promising long-term benefit of the PEER 

program. • 

References 

• Bandura, A. (1986). Social foundations of 

thought and action: A social cognitive theory. 

Englewood Cliffs, NJ: Prentice Hall. 

• Morell, P. D., & Lederman, N. G. (1998). 

Students’ attitudes toward school and 

classroom science: Are they independent 

phenomena? Journal of School Science and 

Mathematics, 98(2), 76-83. 

• Pajares, F., & Miller, D. (1994). Role of 

self-efficacy and self-concept beliefs in mathematical 

problem solving: A path analysis. 

Journal of Educational Psychology, 86(2), 

193–203. 

• Sawada, D., Piburn, M.D., Judson, E., 

Turley, J., Falconer, K., Benford, R., & 

Bloom, I. (2002). Measuring reform practices 

in science and mathematics classrooms: 

The reformed teaching observation protocol. 

Journal of School Science and Mathematics, 

102(6), October, 245-253. 

• Weinburgh, M. (2003). Confronting and 

changing middle school teachers’ perception 

of scientific methodology. Journal of School 

Science and Mathematics, 103(5), 222-232. 

The Making of Free Teacher-Requested Resources 

Bill Klemm and Larry Johnson 

Middle school teachers need a singlesource 

electronic access point that allows 

them to search for instructional resources 

that are tagged by grade level and subject 

matter, designed by content specialists 

and refined by teachers. 

Our program offers an Internet-based 

nationwide service to science and math 

teachers by providing them with quality 

demonstrations and activities. After 

submitting an online request, one of our 

honors Undergraduate Fellows selects the 

request, performs the initial work, and 

requests review and assistance from one 

of our GK-12 Graduate Fellows. After 

interacting to produce a draft response 

that includes state knowledge standards, 

the GK-12 Graduate Fellow submits the 

materials back to the requesting teacher 

and to our website library of resources 

(peer.tamu.edu/DLC/NSF_Resources. 

asp), whereupon an automated e-mail 

notification is sent to a professor specializing 

in that area. The professor suggests 

changes as needed, which are then 

incorporated and re-submitted to the 

professor. Once the response is deemed 

acceptable by the professor, an automated 

e-mail notification is sent to a middle 

school teacher specializing in that area. 

The teacher suggests changes as needed, 

which are incorporated and re-submitted 

back to the teacher. Upon teacher acceptance, 

it is approved and automatically 

goes to our live website as a “Teacher 

Requested Resource.” All materials in the 

library are searchable by subject, content 

category (lesson plans, computer activities, 

teaching content, self-directed), and 

grade. 

We created this resource system because 

we wanted our Fellows to have access to 

a variety of activities and demonstrations 

that would interest and engage the students. 

We knew that Fellows would want 

to generate their own lessons, because 

of their own academic experience and 

because lessons that are publicly available 

are either hard to find, inappropriate, 

or inadequate. The Principal Investigators 

of PEER insisted that Graduate Fellows 

document their lessons in a formal lesson 

plan, using the lesson plan format that 

had been developed by the NSF GK-12 

group at Duke University. However, not 

all requests require a full lesson plan. 

Some of the materials are answers to 

Diagram of the iterative process for developing responses for teacher requests. 

questions or a list of websites. The library 

is searchable by subject, grade, and 

content category. 

When teachers want to submit a request 

via the website, they see initial choice 

options to browse what is in the database 

or to submit a request. Teachers typically 

browse to see what is already available 

or search by category, subject matter, or 

by grade. Though the website houses 

mostly middle school lessons, many can 

be scaled up or down for other grades. 

In the browse mode, teachers see the title 

and a brief description of the items in the 

database, which are hyperlinked to the 

lesson plan. • 

Distance Learning Community 


Adventures of an Undergraduate Fellow 


I make a list so I don’t forget to bring 

my cardboard models and a sheet so that 

the students can’t see the models until 

I’m ready. I bring a few books about 

architects, a ladder, and a flashlight. I 

make a few printouts for props during 

my lesson, and I bring 

a tape measure for the 

tower-building contest. 

Though my job is not 

going into schools, today 

is different. I have 

been invited to speak 

about architecture. 

This is not the first 

time, but every time 

I go, the experience 

is different. I tell the 

students about architecture 

and how it 

relates to mathematics. 

We talk about different 

careers for people who 

get a degree in architecture. 

I show them 

pictures of famous 

logos, which help describe 

the way people 

view their world, an 

important aspect of architecture. They 

raise their hands to answer my questions. 

The best part of the whole event is when 

I open the ceiling. It works for buildings 

that have a suspended ceiling, with 

fluorescent lights and air conditioning 

NSF GK-12 Undergraduate Fellow, 

Virginia Traweek, talks about 

classroom architecture with a group of 

Jane Long Middle School students. 

ducts spaced at intervals. I move one 

of the tiles and talk about what makes 

a building function. I point out wires 

and plumbing. The students are amazed 

that anyone would have the audacity to 

look into the ceiling. They ask questions 

which sometimes 

delve into topics such as 

ethics and professional 

standards. Some students 

have parents who work in 

the construction field, but 

all of the students seem to 

be engaged. 

At the end, I show my 

models and talk about 

how long it took to build 

the tiny cardboard houses. 

Then I let the students 

build their own models 

out of toothpicks and 

gumdrops. They go to 

work, and soon we’ve 

got towers that are two or 

three feet tall. 

Soon the teacher announces 

that class is almost 

over. Students begin 

cleaning their desks and asking if they 

can eat their gumdrops. A few approach 

me to return the books I brought. They 

ask me questions about architecture, and 

I answer as honestly as I can. The teacher 

thanks me. “I’m so glad you came,” 

she says. “It’s good for them to see a 

woman in a mathematics-related career.” 

I tell her it was no problem. It really is 

no problem. Coordinating my schedule 

with a public school classroom is sometimes 

difficult, but for a person who has 

always wanted to work as an educator, it 

has been both the most frightening and 

exhilarating experience of my undergraduate 

(and now graduate) career. 

I’ve learned that I do not possess the 

energy to teach seven classes in a row. I 

know that the challenges of having a new 

lesson prepared every day for students 

of different ages and grade levels can be 

overwhelming at times. However, the 

ability to share knowledge with another 

group of people is amazing. I try to present 

things that will be fun for the students, 

which means I have to remember 

what first amazed me about architecture. 

If I can communicate that, I’ve shared 

a piece of myself with a whole group 

of young minds (at least, younger than 

mine). 

When I get home from my visit, I’m 

usually exhausted. Still, it’s a rewarding 

experience. I’m getting an opportunity to 

give back, an experience few of my peers 

have had. It’s not that I want architecture 

to be their future career, but I want to 

make sure they know it’s an option. • 

Virginia Traweek served as an 

Undergraduate Fellow in 2004-2005. 

She is currently a Graduate Fellow. 

Undergraduate Comments 

I have been assisting Michael Karka this 

semester with his work at Snook Middle 

School. The bulk of my assistance has 

come in the form of brainstorming with 

Michael and developing activities to be 

used in the classroom to reinforce the 

concepts the students are learning. On 

one occasion, I worked with Michael 

to carry out two outdoor activities that 

we had developed, a “math sack race,” 

which allowed students to practice 

multiplication and division of positive 

and negative integers, and a “metric 


Olympics,” which allowed them to practice 

measurement and conversion skills. 

The students responded very positively 

to these activities and it was great for 

me to get the chance to interact with the 

students and see the end result of the 

activities we developed. 

- Ryan Newman 

Every week, I brainstorm activities for 

my GK-12 Graduate Fellow and then 

prepare an activity for him to present to 

his seventh grade class. Last Friday, I 

went with him to Hearne Middle School 

and helped present an activity on scaling 

in mathematics. We had the students 

make scale models of cars, people, and 

buildings in order to teach them scaling 

and proportion. The lesson was definitely 

a success! 

- Sarah Schott 

I have gone to Snook and presented a 

physics lesson that I had written the day 

before! Through the PEER program, 

I have done TAKS tutoring for Snook 

ISD and volunteered for the TAMU 

math camp, which was a blast! 

- Ross Shockley

Teaching Philosophy of a Scientist 

Larry Johnson 

Driven by curiosity and imagination, 

humanity distinguishes itself by the 

desire to learn. People want to elucidate 

mechanisms, predict outcomes, prevent 

undesirable situations or consequences, 

and plan for the future for themselves, 

their families, and for humanity. Young 

learners quickly realize the power of 

knowledge to establish and maintain 

self-esteem, to communicate with peers 

and others on interesting topics, to solve 

problems, and to overcome socioeconomic 

barriers. 

A teacher’s role is to facilitate students’ 

desire to learn through helping them 

develop their knowledge base, their 

life-long learning skills, and their career 

choices. Teachers direct thinking behavior, 

motivate and encourage students, 

widen students’ self-expectations and 

self-evaluation, and expand their opportunities 

and career choices. 

Teachers can make a difference in the 

lives of their students. This includes immediate 

and life-long learning behavior, 

development of learning skills, and direction 

of careers. How many people in academia 

can cite the “third grade teacher” 

or “college professor” who would not 

accept mediocrity, who directed them to a 

certain life-changing book, who widened 

their opportunity, or who prevented a 

FellowSpeak 

Tips for a successful activity 

• Make it shorter than the time you have. 

If class is 45 minutes, aim for a 20 minute 

activity. 

• Try to involve the entire class. 

• Limit the amount of lecturing time. 

• Be able to adapt to the class’ skill level. 

• Make the activity as simple as possible. 

The higher-level students will ask good 

questions. 

• Make the set-up easy for the teacher. 

• Limit preparation and clean-up. 

• Be enthusiastic. 

• Rewards and competition always encourage 

participation. 

• Always have a “Plan B.” 

wrong decision? 

Teaching yields “immediate gratification” 

for one’s efforts. The evidence 

of one’s educational approach or point 

made is immediate in students’ faces, 

behavior, or questions they can now ask. 

There are distinct behaviors that indicate 

students are learning. “Oh, so that’s how 

it works,” a student may say. When a 

research discovery is made, there is at 

least 95% effort on verification, and an 

expected delay in acceptance of one’s 

discovery by the public. In teaching, the 

class is the public. Teaching allows scientists 

to try different ideas or approaches, 

to hold an investigation of what works 

with a given group, with students being 

the study subjects. 

In summary, teaching represents a unique 

opportunity instructors have to mold and 

Wings Across Texas 

November 2002 to May 2005 

Jon F. Hunter, Professor 

Dr. Johnson demonstrates lung capacity during 

a scientist visit. 

direct academic lives of students and to 

facilitate the students’ inherent desire to 

learn through stimulation of their curiosity 

and imagination. In return, instructors 

stay young in their thoughts, stay interested 

and stimulated in their subject, stay 

current, and enjoy immediate gratification 

for having affected a small part of 

humanity. • 

Wings Across Texas is an airborne mechanism for university scientists to reach rural 

public schools: 

• 285 presentations to students attending 59 rural middle/junior high schools in 49 

Texas counties 

• Student contact: 9,832 hours 

• Demographics: 63.6% Hispanic, 33.2% White, 2.6% African American, 0.2% Native 

American, and 0.4% Asian; 62% of these students are on the free lunch program 

• Total distance traveled: 76,440 nautical air miles (equivalent to 97,264 statute 

highway miles) 

• 128 scientists’ visits: Tuesdays and Thursdays (November 2002 – May 2005) 

• Averages: 34 students per presentation and 597 nautical miles (equivalent to 760 

highway miles) travel per trip 

E-mail from Ms. Sandra Weaver (Hardin Middle School) - November 3, 2004 

Dr. Hunter and Adam, 

Thanks so very much for the wonderful visit yesterday. The other teachers were 

coming to me after school asking what I had going on because it was the talk of the 

school. It seems that the first group of students filled everyone in on the wonderful 

program. The winners were sporting their shirts and calculators today. We had testing 

all morning, so I didn’t get to visit with all students today. I will have them fill 

out the evaluations tomorrow. I will send the evaluations and copies of the pictures 

to you. Thanks again so much, I don’t think either one of you really know how 

much of a positive impact you have on these kids. 

Presentations included: Water Quality; Air Quality; Enterobacteriaceae; The Jade 

Dragon; Texas: 1867; and Three Rivers, Three Nations 


Calculating Surface Area 

Under Pressure! 

Ryan Pedrigi 

Target grade level: 8 

Time Required: One class period 

TEKS objectives: 

8th grade math: 8.1 B, 8.2 A,B,C,D, 

8.8 C, 8.14 B,C,D, 8.15 A 

rational numbers, real-life problems, 

appropriate operations, volume and 

surface area, problem-solving strategies, 

communicating mathematical 

ideas 

Materials: 

“Calculating Surface Area Under 

Pressure” worksheet 

One 3-D object, such as a box, per 

group 

Two nails (for measuring/calculating 

the area of the tip versus head) per 

group 

Two tape measures per group 

Balloons (optional) 

Hammer and wood (optional) 

Cost per group: Approximately 

$1.00 

Activity Summary: 

The primary focus of this lesson is 

to introduce the basic qualitative 

concepts and associated mathematical 

formulations for pressure. The 

motivation is to introduce the students 

to a physical application involving the 

measurement and/or computation of 

surface area, which is treated as a secondary 

objective. This lesson begins 

with a short presentation that qualitatively 

defines pressure through examples. 

This gives students a tangible 

representation of concepts related to 


pressure and surface area. Once students 

understand the concept, they are 

given the mathematical formulation. 

There are then two quick examples, 

using the pressure formula, followed 

by two short activities requiring measurement 

and computation of surface 

area in order to calculate either force 

or pressure. 

Activity Plan: 

This activity introduces a creative 

way to practice measuring and calculating 

surface area. At the same time, 

it introduces pressure, a physical 

principle commonly used in science, 

technology, and everyday life. The 

activity begins with a presentation 

of qualitative examples of pressure. 

Students are asked to follow along 

with the provided worksheet (see 

“Calculating Surface Area Under 

Pressure” worksheet, page 24) in order 

to maintain their focus. To make 

the presentation more interactive, a 

student volunteer is asked to come to 

the front to demonstrate a push-up. 

The first is a normal push-up, where 

the student’s palms are in full contact 

with the floor. The second is made 

harder by asking that the student do 

the push-up using only his or her fingertips. 

This type of push-up proves 

to be harder because the fingertips 

provide significantly less surface area 

over which the student can exert a 

force to produce the motion. This 

means there is more pressure on the 

fingertips. In this case, the force is 

the weight of the body, the area is the 

surface of the hand or fingertips, and 

the pressure is the level of difficulty 

in completing the push-up. 

Pressure Concepts: 

Pressure is the application of a force 

(a push or pull) over a surface. Pressure 

is the ratio of force to surface 

area. Pressure is an important element 

in many parts of nature, such 

as in scuba diving or in keeping tires 

inflated and functional. For example, 

the pressure inside a balloon increases 

as air in the balloon increases. The 

balloon finally pops when the pressure 

is too much for the balloon to 

hold. 

Applications of pressure include the 

heart pushing blood through the body, 

(blood pressure), divers worrying 

about the amount of air in their bodies 

and kids using a bike pump to inflate 

tires. 

Provide the formula: 

Pressure = Force / Area 

Give a very simple example of its use: 

A force of five pounds acting over 

a surface of five inches square has a 

pressure of 1 psi (pounds per square 

inch). 

Once students are comfortable with 

the use of this formula, they are 

given two problems that reinforce 

their mathematical understanding of 

pressure. These should be worked 

out individually, but with the teacher 

leading students to the solution.

Problem #1: 

The deepest part of the ocean is about 

32,000 feet deep, where the 

pressure is about 16,000 psi. What 

is the total force acting on a submarine 

that has a surface area of 

8,000,000 square inches? Answer: 

Force = 16,000 pounds per square 

inch * 8,000,000 square inches = 

128,000,000,000 pounds 

Problem #2: 

The rupture pressure in a balloon is 

0.25 psi. If the radius of the spherical 

balloon right before rupture is six 

inches, what is the force acting 

on the inner wall of the balloon? 

(Surface area of a sphere = 4 * 

pi * radius squared) Answer: 

Force = 0.25 pounds per square 

inch * 4 * pi * 6 inches squared 

= 113 pounds 

Finally, two brief activity questions 

are given to allow students to work a 

pressure computation that requires the 

measurement of surface area (using 

the tape measure provided): 

Activity #1: 

Why is it much easier to hammer 

the tip of a nail into wood versus 

the head? Assuming that the hammer 

exerts a force of 200 pounds 

on the nail, calculate the pressure 

exerted on the wood by 

the nail for (a) hammering the 

tip of the nail into the wood 

and (b) hammering the head 

of the nail into wood. 

The teacher can demonstrate 

this phenomenon for 

the class by attempting to 

drive a nail into a block of 

wood (attempting 

each end 

separately). 

In order to 

show that the 

answer is related 

to the pressure 

exerted by each end of the nail on the 

block, students compute the pressure 

for both scenarios. They will need a 

nail and tape measure to measure the 

radius of both the tip and head of the 

nail in order to compute surface area. 

The calculations will demonstrate that 

the tip of the nail exerts a much larger 

pressure than the head because of its 

smaller surface area. 

Activity #2: 

Pretend that the 

3-D object 

given to 

your group 

is a submarine. 

Calculate the force acting over the 

entire surface area of your submarine 

if the dive depth is 1,000 feet, which 

corresponds to a water pressure of 

445 psi. 

The students should be given a box 

that they use as a make-believe submarine 

resting at a depth of 1,000 feet 

(corresponding to a pressure of 445 

psi). The students will again need to 

measure the dimensions of the object 

and calculate surface area, and then 

calculate force using the pressure 

equation. 

The lesson is finished when the final 

activity problem has been solved. The 

solutions to these activity problems 

(or the individual problems) can be 

discussed as a class or the teacher 

may choose to have students 

turn in their solutions for assessment. 

• 


Name: Date: Class period: 

1. What is force? 

Calculating Surface Area Under Pressure 

2. What is pressure? 

3. What does “psi” stand for? 

4. What is the formula used to find the area of a circle? 

5. What is the formula used to find pressure? 

6. What do the following letters represent? Remember to include units. 

P = 

F = 

A = 

7. EXAMPLE PROBLEM 1: Submarine (show all work) 

Partnership for Environmental Education and Rural Health Worksheet 

8. EXAMPLE PROBLEM 2: Balloon (show all work) 

9. NAIL PROBLEM (with group) 

10. SUBMARINE PROBLEM (with group) 


Crank Up the Volume!! 


This lab consists of a series of stations. 

Students will rotate through 

each station and answer the questions 

on the worksheet “Crank Up The 


Time Required: One to two class 

periods 


8th grade science: 8.1 A, 8.2 B-D, 

8.4 A, 8.7 A, 8.9 D 

lab skills, scientific method, scientific 

tools, force and motion, physical 

and chemical properties 

Materials: 

Crank Up the Volume! worksheet 

Station 1 (per station): 

250 ml or large beaker or cup - salt 

Pan (or tuning fork) 

Saran Wrap 

Wooden spoon 

Rubber band 


Five 16 oz glass bottles 

Spoon 

Graduated cylinder 

Access to a freezer 

Demonstrating the Movement of Sound 

Danielle Lewis and Kelly Lazo 

Volume.” The class size may warrant 

duplicate stations. Depending on the 

level of the student, the teacher may 

need to read through the worksheet 

with the students. The set-up for this 

activity is described below in Materials 

List and Set-up. Students should 

already have been introduced to the 

concept of waves. 

Vocabulary: 

Wave: a disturbance that propagates 

and carries energy through matter or 

space. 

Vibration: the back and forth movement 

of molecules. 

Medium: any substance through 

which waves can travel. 

Station 1: Time for the Salt 

Dance! 

Cover the top of a cup or beaker with 

a piece of Saran Wrap. Use a rubber 

band to secure the Saran Wrap. Place 

a small amount of salt on the Saran 

Wrap. Students will use the wooden 

spoon and pan to discover that the 

sound waves produced by hitting the 

pan will cause the salt to jump! 

tap on the bottles and determine the 

difference in pitch. 

Part III – Homemade Telephones 

Use a nail to punch a small hole in 

the bottom of each of six tin cans. 

Thread string of varying thicknesses 

and lengths through each can and 

knot the string or use a button to secure 

the string inside the can. There 

should be two cans per string for each 

phone. One student talks into the 

phone. The second student listens 

on the other end. Students determine 

which phone made it easiest to hear. 

Students should keep the string tight. 

Part IV – Eh, What Did You Say? 

Students make a cone out of paper 

and tape it. They cut a small hole in 

the closed end of the cone and place it 

in their ear, amplifying sounds in the 

room. 

Stations III and IV are listed on the 

worksheets. • 


Three tin can phones 

String of two different thicknesses, 

(Two cut to the length of the room, 

plus one cut longer than the others) 

Six tin cans 

Six buttons 

Electrical tape (to smooth the rough 

edges of the tin can) 


Sheet of paper for each person 

Tape 

Cost per group: $2.00 

Station 2: Sound Through Different 

Media 

Part I – Characteristics of Sound 

(See worksheet, page 26.) 

Part II – How does the amount of water 

in the bottle affect the sound? 

(See worksheet.) 

Root beer or cream soda bottles work 

very well for this activity. Fill the 

bottles with 50 mL, 100 mL, 200 mL, 

and 300 mL of water. For the bottle 

that will contain frozen water, add 

100-150 mL of water to it 24 hours 

prior to the activity. Do not leave the 

cap on or fill it too full, as the bottle 

may break. Students use a spoon to 



Crank Up the Volume! 

Station 1: Time for the Salt Dance! 

Materials per station: 250 mL or large beaker Saran Wrap salt 

pan (or tuning fork) wooden spoon rubber band 

Sound is produced by a back and forth motion called a vibration. Sound travels 

in waves from one place to another and it travels in all directions away from the 

source. 

1. Sound travels as what kind of wave? 

Answer: Sound travels as a longitudinal wave. 

2. Place the Saran Wrap over the beaker and secure the Saran Wrap with a rubber band. 

3. Place salt on top of the Saran Wrap. 

4. Hold the pan over the beaker and salt and hit the pan with the wooden spoon. 

5. Describe what happened to the salt. 

Answer: The salt dances! It moves up and down as you hit the pan with the wooden spoon. 

6. What caused the salt to act the way it did? 

Answer: Vibrations cause the salt to “dance.” 

Station 2: Sound Through Different Media 

Part I 

In order for sound to travel, it must be transported in a medium. 

1. Name two substances (mediums) that transport sound. 

Answer: Water, air, and solid objects transport sound. 


2. Place your ear on the side of the table. 

3. Have your partner scratch lightly on the other side of the table. 

4. What do you hear? 

Answer: You hear a scratching noise. 

5. Can sound travel through solid substances? 

Answer: Yes. 

Part II – How does the amount of water in the bottle affect the sound? 

For this exercise, you will use the four glass bottles filled with water on the table and ask your teacher for the 5th glass 

bottle in the freezer. The amount of water in each bottle is as follows: 

1 = 50 mL 2 = 100 mL 3 = 200 mL 4 = 300 mL 5 = 50-100 mL frozen 

Your mission is to determine if the volume of fluid in the bottles affects the pitch of the sound made when you tap a 

spoon against each bottle. Pitch is how high or how low a sound is perceived to be. 



For this exercise, write a hypothesis stating whether you think the sound will change or will stay the same. 

1. I believe that when I tap a spoon against the side of the bottles containing different amounts of water, the pitch 

will ___________________________________________________________________________________________. 

2. Now tap the spoon against the side of each bottle. 

3. Record your results in the data table. If the sound doesn’t change, write “no change.” If the sound changed, write 

how it changed compared to the previous bottle – did the noise get softer, higher pitched, lower pitched, was it easier or 

harder to hear, etc. 

Bottle 1-50 mL Bottle 2-100 mL Bottle 3-200 mL Bottle 4-300 mL Bottle 5-frozen 

Answer: The pitch decreases as the volume of water increases. 

4. Was your hypothesis supported by the evidence? Explain your answer. 

Answer: Students should examine their original hypothesis and decide whether they were correct 

or incorrect. 

Part III – Homemade Telephones 

I bet you always wondered if you could hear through a tin can telephone. Well today, you will find out. 

1. In front of you are three “telephones.” You and your partner should stretch the phones out. 

2. Put your tin can next to your ear while your partner talks into the other can. 

3. Change roles so that you both get a chance to listen. 

4. Record your observations below. Be sure to include whether it was easier or harder to hear your partner when you 

used each of the three tin can phones. 

Tin can with thin string 

Crank Up the Volume!, Page 2 

Tin can with thick string 

Tin can with extra long string 

Answer: The tin can that contained the thickest string should have the clearest sound. This is because 

the medium is more substantial. 


Crank Up the Volume! Page 3 

5. Based on your observations, on which tin can phone was it easier to hear? 

Answer: Students should review their data and observations and write down the tin can phone design 

that made it easiest to hear. 

Part IV - Eh? What did you say? 

Vibrations and air movement occur when an object moves. This movement results in sound. Your ear is specially designed 

to pick up on these vibrations and air currents. 

1. Take the large sheet of paper at your desk and roll it into a cone shape. 

2. Make one end as large as you can. 

3. Use your scissors if necessary to make a hole as big as a dime or penny in the other end. 

4. Use tape to secure the cone so that it stays together. 

5. Hold the small end of the cone to your ear and listen. 

6. Does the cone enhance your hearing? 

Answer: Yes. 

7. Explain your answer. Why did you say yes or no to Question 6? 

Answer: Students should describe what happened to the sound in the room when they placed the 

cone up to their ear. 

8. Are there similarities between the shape of the cone and our ears? Explain your answer. 

Answer: Yes, the ear also has a cone-shaped design to help pick up and amplify vibrations caused 

by sound waves. 



Folding in Scientific Method 

Paper Airplanes and Scientific Principles 

Melanie Ramon 




7th grade science: 7.1 A, 7.2 B-E, 

7.6 A,B 

lab skills, scientific method, force 

and motion 

Materials: 

paper, copies of graphs shown at 

bottom of page 

Cost per group: None 

It is sometimes difficult for students 

to understand how the scientific method 

is used in real-world situations. In 

this activity, students design paper 

airplanes and develop a hypothesis regarding 

which one will fly the farthest 

distance or at the fastest speed. Using 

stopwatches and metersticks, students 

test their models in several different 

trials. They fold a standard paper 

airplane, an airplane with a paper clip 

on the nose, an airplane with flaps 

on the wings, and an airplane of their 

own design. For each trial, students 

measure the distance traveled and 

calculate the speed for each plane 

and determine if their hypothesis 

was supported by data produced. 

Below is a graph on which students 

can record their speeds and 

distances. They calculate speed 

by dividing the distance flown by 

the number of seconds. An extension 

of this activity is graphing 

results to look for trends, 

then comparing them to fellow 

classmates’ results. 


Day 1: 

Build Airplane Models 

Days 2 and 3: 

Test Fly the Airplanes 

Day 4: 

Graph the Data 

A middle school student folds her airplane for the tests. 

“The students really enjoyed being able to get out of the classroom 

and do a hands-on activity. The students who won the competition 

were so proud that they came up with an idea, took that idea and 

built it, and then put it into action. The students became very interested 

in airplane-building and some of the students were even motivated 

to do some research about airplanes on their own. We had 

a discussion about the costs of developing a new airplane design. 

The students learned that building several designs and testing them 

all would end up being quite expensive in the real world and that a 

great deal of math is involved in developing a new design.” 

Melanie Ramon, NSF GK-12 Graduate Fellow 

Model Trial 1 Distance Trial 2 Distance Trial 3 Distance Average Distance 

Standard 

Paper clip 

Flaps 

Personal Design 

Model Trial 1 Speed Trial 2 Speed Trial 3 Speed Average Speed 

Standard 

Paper clip 

Flaps 

Personal Design 


Rational Code Cracking 

Bruce Ngo 




In this lesson, the students calculate 

the answers to rational expressions in 

order to crack a “secret code.” Answers 

are positive or negative rational 

numbers written either as fractions 

or as decimals. Expressions involve 

adding and subtracting positive and 

negative rational numbers. Each expression 

will be written on a notecard, 

with the associated letter on the back, 

and placed at several stations in the 

classroom. The activity uses a “rotation” 

approach through the stations to 

get students active and interested. 

Activity Motivation: 

Spies often use codes to communicate 

secret information. They are always 

on the move to keep from getting 

caught. Students will move from 

desk to desk, solving math problems 

to discover clues that will help them 

decipher their secret message. 


1. Make notecards with the mathematical 

expressions listed in the table 

to the right. There are 15 different 

letters associated with the expressions. 

Students need to solve these 

expressions in order to match the letter 

to the value. Each notecard should 

have the expression written on the 

front and the associated letter written 

on the back. 

2. Designate enough stations so that 

there will be one notecard at each 

station. 

3. The “Rational Code Cracking” 

worksheet has the four expressions 

listed in code format. Tell the students 

that they must use the clues left 

by the mathematician spy in order to 

decode the secret message. 

4. Students will have a limited 

amount of time at each station to 

solve the expression. Make sure the 

students write down the expression 

and the associated letter even if they 

cannot solve the problem in time. 

5. After the allotted time is up, the 

students must move to the next station. 

With 15 stations and a 45-minute 

class, students can have roughly 

2 minutes to solve the problem and 

1 minute to rotate. You may need to 

adjust these times depending on how 

confident the students are with solving 

the problems and how well they 

make the transition to the next station. 

Activity Scaling: 

The expressions can be altered in 

order to match the capability of the 

students. Time available for solving 

the problems could also be adjusted. 

TOP SECRET 


7th grade math:7.1 B, 7.2 B,G, 7.14 

A,B, 7.15 A,B 

converting, adding, subtracting and 

multiplying fractions, decimals and 

whole numbers, communicating 

mathematical ideas, logical 

reasoning 

Materials: 

Notecards 

“Rational Code Cracking” 

worksheet 


Simpler messages with fewer letters 

would allow more time at the stations 

to solve the problems. • 

Station Answer Expression #1 Expression #2 Letter 

1 -8.3 -5.6 + -2.7 -10 + 1.7 M 

2 -4.4 -8.1 + 3.7 -2.1 - 2.3 A 

3 5/6 1 1/2 + -2/3 -3 1/3 + 4 1/6 T 

4 34.6 23.4 - -11.2 H 

5 -59 -34.2 - 24.8 -12.4 + -46.6 E 

6 -1 3/4 -3 1/4 - -1 1/2 -2 5/8 - -7/8 I 

7 78 45.2 - -32.8 87.5 + -9.5 C 

8 1 1/4 2 3/4 - 1 1/2 -3/4 + 2 S 

9 -23/9 -17/1 + -6.8 -13.1 - 10.8 N 

10 -97.8 -73.7 + -24.1 F 

11 -6.9 -15.3 - -8.4 U 

12 41.6 45.1 + -3.5 R 

13 -24.6 -10 - 14.6 L 

14 4/5 -1 1/2 - -2 3/10 O 

15 2 1/2 5 1/3 - 2 5/6 G 

Message # Coded Message Order 

1 Science is fun. 8-7-6-5-9-7-5-6-8-10-11-9 

2 Mathematics 1-2-3-4-5-1-2-3-6-7-8 

3 Rationals 12-2-3-6-14-9-2-13-8 

4 Math is great. 1-2-3-4-6-8-15-12-5-2-3 




Rational Code Cracking 

In order to crack the code, you need to solve the problems below. Copy the problem 

from the notecard onto your scratch paper and solve. Match your answer and fill in 

the letter on the card. Remember to show all of your work! You have been handed a 

top-secret, encrypted message from a mathematician spy. 

Message #1 

1 1/4 78 -1 3/4 -59 -23.9 78 -59 -1 3/4 1 1/4 -97.8 -6.9 -23.9 

Message #2 

-8.3 -4.4 5/6 34.6 -59 -8.3 -4.4 5/6 -1 3/4 78 1 1/4 

Message #3 

41.6 -4.4 5/6 -1 3/4 4/5 -23.9 -4.4 -24.6 1 1/4 

Message #4 

-8.3 -4.4 5/6 34.6 -1 3/4 1 1/4 2 1/2 41.6 -59 -4.4 5/6 


Shoebox 

Apartments 

Candace DiBiano 

“You have just decided to move into an 

apartment with two roommates. You need to 

design the interior of each bedroom and buy 

the materials and furniture you will need.” 


In this activity, students explore area, perimeter, and 

volume by building miniature apartments in shoe boxes. 

They find the amount of wallpaper and carpeting they 

need, calculate the amount of space various decorations 

will use, and then calculate how much trim is needed to go 

around the different shapes. 

Preparation: 

Collect a shoebox for each student 

or group of students and cut out a 

rectangular door and several windows. 

Depending on grade level, 

the windows can be any shape from 

a simple triangle or square to more 

complex shapes like semi-circles, 

trapezoids, or combinations of shapes 

stuck together. Discuss how math can 

be used in fields like architecture and 

interior design. Ask how much math 

is required to be an interior designer. 

Step 1: Measuring the Box 

Have students measure the dimen- 

Target grade level: 6 (modifiable to 

5th-8th grades) 

Time Required: Four to five class 

periods 


6.2 B, 6.2 D, 6.4 B, 6.6 C, 6.8 B, 

6.6 C, 6.8 B, 6.12 A 

addition and subtraction, fractions 

and decimals, estimating, formulas, 

measuring, geometric relationships, 

communicating mathematical ideas 

Materials: 

Shoeboxes 

Magazines 

Construction paper 

Rulers 

Foam paper or felt 

Various craft materials 


sions of their shoebox. From these 

dimensions, students will calculate 

the box’s volume. 

Step 2: Flooring 

From the measured data, students will 

calculate how much carpet they need 

to cover the floor of the apartment, 

and will cut the carpet, and install it 


in their apartment. Brightly colored 

foam sheets can be used for this step. 

Step 3: Wallpaper 

Students use the dimensions of the 

box to measure the area of the four 

walls for wallpaper. They subtract the 

area of the windows and doors to get 

a total of how much wallpaper will 

be necessary. Students then cut and 

install the wallpaper. Wrapping paper 

with fun patterns can be used for this 

since actual wallpaper is too heavy. 

Step 4: Wall Decorations 

Students put objects shaped like rectangles, 

circles, triangles, and trapezoids 

on their walls. Students calculate 

how much wall space each object 

doors, wall decorations, and the top 

of their apartment. Before they add 

trim, they will need to calculate how 

much trim it will take to go around 

the various shapes. To do this, they 

will first calculate the perimeter of 

these shapes. Yarn, string, or ribbon 

work well for trim. 

When the apartments are complete, 

students vote on their favorites and 

award prizes for top apartments. 

Extension: 

An extension for this activity is to 

use a scale, such as 1cm = 0.5m, for 

the apartment. Have students find 

the scaled dimensions of their box 

and calculate the amount of carpeting, 

wallpaper, and trim required. 

Give prices for carpet, wallpaper and 

trim per square meter. Have students 

calculate the cost to install each into 

their apartment. Another extension 

is to charge for furnishings or to have 

students create a budget and plan for 

certain purchases in their apartments. 

This gives students an idea of what 

it might be like to furnish an apartment 

in the “real world.” Discussion 

should include occupations, like 

contractors and architects, that necessitate 

estimating. • 

“It was fun to be able to win 

prizes and get furniture for our 

apartments. I’ve been kind of 

interested in architecture.” 

- Iola ISD Student 

will need. Photos of the students cut 

into the different shapes or miniature 

mirrors can be used. 

Step 5: Floor Furniture 

Students add tables, chairs, and a bed 

and calculate how much floor space 

they require. Painted wooden or styrofoam 

blocks decorated with fabrics 

make good beds. Students will also 

be given a rectangular prism fish tank. 

They will find its volume, convert the 

calculation to milliliters, and then fill 

the fish tank from a graduated cylinder 

to check their work. Small clear 

plastic containers are available at any 

craft store. 

Step 6: Trim 

Students add trim around windows, 

FellowSpeak 

Tips for handling your first days in the classroom: 

• Work one-on-one with students or in small groups. 

• Learn the students’ names, interests, and thoughts about math and science. 

• Let students know that you’re interested in their interests. 

• Explain your role as a Resident Scientist/Mathematician. 

• Try to be comfortable with the kids. 

• Make a video or presentation showing your interests to give the students an idea of 

what your life is like outside of the classroom. 

• Work with your teacher ahead of time to build a friendship. 

• Look for opportunities like clubs and extracurricular activities to interact with the kids 

outside of class. 

Tips for connecting with problem kids: 

• Ask them a question. 

• Use their name. 

• Indicate that participation requires good behavior. 

• Have a worksheet ready for nonparticipating students. 

• Hold an outside conference with their teacher. 

An Iola ISD student shows her apartment, which has 

blue wallpaper and carpet. 


Walk This Way: Interpreting Motion Graphs 

Jan Fechhelm, CSISD Teacher, and John Nelson 



Developing and interpreting motion graphs can often be challenging 

for middle school students. This activity requires no involved technology 

and limited equipment, and teaches students to model the motion 

shown in time/distance graphs using their physical movements. 

While they themselves may be in 

constant motion, getting middle 

school students to really understand 

the motion shown in time/distance 

graphs can often be a challenge – but 

it’s a challenge that must be taken! 

In virtually every listing of national 

and state science standards for middle 

school students, the concept of graphically 

representing motion is included. 

In the National Science Standards for 

Middle School, Benchmark 3 states 

that middle school students should 

“Know that an object’s motion can be 

described and represented graphically 

according to its position, direction of 

motion and speed.” In past years, my 

sixth grade students have measured 

and graphed the movement of toy 

cars, made graphs describing a walk 

through a local shopping mall, and 

even walked, hopped, and stood still 

so they could then graph their motion. 

And while these were all “successful” 

activities, I could tell by the students’ 

answers on assessments that they 

never really got it. Another option, if 

available, is to use graphing calculators 

and motion detectors. Yet, while 

that is a lot of fun for students and 

introduces them to technology they 

will undoubtedly be using in higher 

grades, this, likewise, left me feeling 

that my students still did not have a 

solid grasp of the concepts involved. 

lesson where students try to move in 

such a way that their movement mirrors 

a given time/distance graph. And 

as any middle school teacher knows, 

a lesson that involves kinesthetic activities 

has a more lasting impression 

on students and leads to a deeper understanding 

of the material presented. 

In other words, any lesson that allows 

middle school students to get up out 

of their seats and move while they are 

learning is a good choice! 

To begin the lesson, students are 

shown a variety of graphs which 

illustrate basic motion (see below). 

These graphs can be quickly and 



8th grade science: 8.1 A, 8.2 B-E, 

8.4 A, 8.7 A 

lab skills, scientific method, analyzing 

information, force and motion 

Materials: 

Masking tape 

Copies of motion graphs 

Stopwatches 


easily drawn on the board as each 

is discussed and then modeled by 

either a student in the room or the 

teacher. Then the challenge begins. 

(Depending on the length of the class 

period, this could be carried out the 

following day if necessary.) Students 

are randomly assigned to groups of 

I found myself again racking my 

brain to find a lesson that would really 

get the students to understand the 

graphic representation of motion. My 

Graduate Fellow helped me develop a 


Figures illustrating basic motion: A) steady speed (a straight line with a positive 

slope); B) rapid steady speed (a straight line with a steeper slope); C) 

acceleration, D) deceleration (curved lines); E) no movement (a horizontal 

line); and F) starting away from the starting point and returning to it.

three or four. The class moves into 

the hallway, outside, or to any large 

open area. At the center of the area, 

a series of markings are made with 

masking tape at 1 meter intervals and 

marked from 0 meters to 15 meters. 

(With average class size of 32, I had 

four 0-15 meter sections marked off.) 

Two groups are assigned to each set 

of markings, with one group on the 

right side and one on the left. Each 

group is given a basic motion graph 

and a stopwatch. I made a total of 15 

different graphs. The students are 

told to work within their groups to 

see if they can model the movement 

shown in the graph, matching the distance 

traveled and the time intervals. 

Most groups start out unsure of what 

to do, but quickly figure it out. It is 

interesting that students who would 

have had a difficult time in the classroom 

constructing a graph of their 

own often seem to excel at figuring it 

out. 

Groups are allowed to decide their 

own method of completing the challenge 

and the variations are many. 

Most groups divide the tasks, but it 

seems to work best when the students 

are allowed to work out “who does 

what” among themselves. For example, 

one scenario might be to have 

one person acting as the timer and 

using the stopwatch to count the seconds 

aloud. Another group member 

becomes the walker who, holding a 

copy of the graph, tries to match their 

movement to the graph according to 

the time called out by the timer. The 

other students in the group (also with 

copies of the graph) act as directors, 

giving the walker additional information 

such as, “Stay still for 2 seconds,” 

or, “Get ready to turn around 

and head back.” 

Be prepared for noise as the students 

discuss how to model the graph and 

give encouragement and directions to 

the walkers. Most groups 

become very enthusiastic 

about the challenge, 

cheering their walkers 

to success. Once the 

group thinks they can 

model the motion shown 

on the graph, they raise 

their hands and wait for 

the teacher to come and 

observe. If the group 

manages to model the 

movement shown on the 

first graph, they are given 

a second, more complicated 

graph involving 

the movement of two 

people traveling in different 

directions (Fig. 3). 

Group members are told 

to change jobs and begin 

work. 

As the groups become 

more proficient, they 

master the challenges 

faster and faster. After 

most of the groups have 

mastered three different 

graphs, the class returns 

to the classroom where 

the teacher shows the 

students a combination 

graph showing many of 

the possible movements 

the student had just 

modeled (Fig. 4). Allow 

the students, working in 

groups, a few minutes 

to describe the motion 

shown. Virtually all 

groups are able to correctly interpret 

all parts of the graph. Even several 

weeks after completing the activity, 

the majority of students are still 

able to correctly interpret the motion 

shown on graphs. 

This is a science teacher’s dream: no 

special equipment, no extensive prep 

time, fun for the students, and no cost. 

Most importantly, the students learn 

the concept because they are totally 

involved – mind and body! Even 

weeks after completing the activity, 

students continue to come to me 

with ideas on how they could have 

accomplished the challenges more 

efficiently or with suggestions on 

more involved graphs, saying “….you 

could use this one to really stump the 

students next year!” • 


Sequence Races 

Michael Karka 




7th grade math: 7.2 E-G, 7.4 C, 

7.5 A,B 

simplifing expressions, appropriate 

operations, relationship between 

terms in a sequence, equations 

Materials: 

Sequence Races worksheet 



In this activity, students use pattern 

and sequence recognition skills to 

solve problems about sequences. The 

first students to make it through all of 

the problems win. 


The teacher should print out the set 

of sequences, removing those which 

may not be appropriate for the level 

of the students, and attach them to 

the wall at different points (stations) 

around the room (or outside) so that 

the students have room to move. The 

teacher stays at one central point and 

all students start at the first station. 

The students race to solve the problem 

at the station, then line up by the 

teacher to have their answer checked. 

If their solution is correct, the teacher 

directs them to the next station. If it 

is incorrect, they have to go back to 

the station, solve the problem again, 

and get back in line to have their answer 

checked. The winner is the first 

student who makes it through all of 

the problems correctly or the one who 

solves the most problems correctly in 


the time given. Each of the problems 

is a different type of sequence. There 

are arithmetic and geometric number 

sequences that should be familiar, as 

well as some more challenging ones. 

The problems should be set up in 

order from simplest to most challenging. 

Assessment: 

The answers are given below. Teachers 

should check the students’ answers 

at each station before they 

move on to the next. 

Vocabulary / Definitions: 

An arithmetic sequence is a sequence 

of numbers for which the differences 

between successive terms is a 

constant. A geometric sequence is a 

sequence of numbers in which each 

term is given by a multiple (constant 

Answers and Reasoning: 

throughout the sequence) of the previous 

one. 

Activity Extensions: 

For students who finish early, or as an 

extra activity, the teacher could have 

the students come up with their own 

sequences for other students or the 

teacher to solve. 

Troubleshooting Tips: 

If the students seem to get stuck on a 

sequence, the teacher could give them 

a small hint based on the method used 

to generate the sequence. 

Activity Scaling: 

With 15 different sequences, the 

teacher can choose those which are 

appropriate for the class. • 

(1) 13; 3x+1 (arithmetic sequence) 

(2) 37; 6x+13 (arithmetic sequence) 

(3) direction of lines rotates counterclockwise 45˚, shapes: circle, square, 

triangle, repeat 

(4) 81; (3)x (geometric sequence) 

(5) -64; (-4)x (geometric sequence) 

(6) 21; 6+5+4+3+2+1 

(7) 8/27; (2/3)x (geometric sequence) 

(8) 64 stars; on each ring there are twice as many (geometric sequence), 

shapes: circle, square, star, repeat 

(9) 64, 125; x3 

(10) Dark box moves clockwise on corners, outlined box moves counterclockwise 

(corner, side, corner, etc.) and rotates 45˚ each time. 

(11) 19, 39; x2+3 

(12) 21, 34; Fibonacci: xn+2 = xn+1 + xn, x0 = x1 = 1 (each term is the sum 

of the previous two) 

(13) (30,-1); (xn+1, yn+1) = (xnyn , xn-yn) 

(14) 28; xn+3 = xn+2 + xn, x0 = 1, x1 = 2, x2 = 3 (each term is the sum of 

the previous term and the term 3 places back) 

(15) 13112221; 1 is read as “one one” or 11, 11 is read as “two ones” or 21, 21 

is read as “one two and one one” or 1211, 1211 is read as “one one, one two, 

and two ones” or 111221, 111221 is read as “three ones, two twos, one one” or 

312211, 312211 is “one three, one one, two twos and two ones” or 13112221



Station 1 

X 0 1 2 3 4 

Y 1 4 7 10 ? 

What is the next term in the sequence? 

Station 2 

X 0 1 2 3 4 

Y 13 19 25 31 ? 


Station 3 

Sequence Races 

If these are the first 6 members of the sequence, draw the 9th member. 

Station 4 

X 0 1 2 3 4 

Y 1 3 9 27 ? 


Station 5 

X 0 1 2 3 4 

Y 1 -4 16 ? 256 

What is the missing term in the sequence? 


Station 6 

Sequence Races, Page 2 

If these are the first three members of the sequence, how many bowling pins will the 6th 

member have? 

Station 7 

X 0 1 2 3 4 

Y 1 2/3 4/9 ? 16/81 

What is the missing term in the sequence? 

Station 8 


What should be drawn on the outer ring? 

Station 9 

X 0 1 2 3 4 5 

Y 0 1 8 27 ? ? 

What are the next two terms in the sequence? 


Station 10 

Sequence Races, Page 3 


What should the next two boxes look like? 

Station 11 

X 0 1 2 3 4 5 6 

Y 4 7 12 ? 28 28 ? 

What are the two missing terms in the sequence? 

Station 12 

1, 1, 2, 3, 5, 8, 13, ?, ? 

What are the next two terms in the sequence? 

Station 13 

If these are the first four points in the sequence, what are the coordinates of the next point? 

(Hint: Write out the coordinates of the first four points, then try to find a pattern.) 

Station 14 

1, 2, 3, 4, 6, 9, 13, 19, ? 


Station 15 

1, 11, 21, 1211, 1112211, 312211, ? 

What is the next term in the sequence? (Hint: Count the digits and read the digits out loud.) 


How Low Can You Go? 

Kevin Curley and Jan Fechhelm 




6th grade science: 6.1 A, 6.2 

B,C,D,E, 6.4 A, 6.7 A, 6.8 A 

lab skills, scientific method, 

scientific tools, physical and 

chemical properties, energy and 

matter 

Materials List: (per group) 

Two glass beakers (400 mL) 

Ice 

Water 

Thermometer 

Rock salt 

Stopwatch or clock 

Graph paper 

How Low Can You Go? worksheet 


In regions where freezing temperatures 

and snowfall accompany the 

winter months, it is a common practice 

to spread salt and sand over the 

roadways. The primary reason for 

this is not to melt the existing ice, but 

to prevent ice from forming on the 

roads. How does the salt prevent ice 

from forming in freezing temperatures? 


Divide the class into groups of 

three to five students. Using 

the “How Low Can You Go?” 

worksheet, have the students 

conduct the experiment following 

the steps listed. After 

clean-up, demonstrate how 

to construct a line graph of 

the water temperature over 

time. Each student should 

relationship between time and temperature. 

Is it a direct relationship (X 

increases, Y increases) or an inverse 

relationship (X increases, Y decreases)? 

• What effect did adding the salt have 

on the temperature of the ice water? 

Was your conclusion correct or incorrect? 

• Why did the salt affect the temperature 

of the ice water mixture? 

Safety Issues: 

Rock salt is not the same as 

table salt and is not edible. 


This simple activity allows 

students to measure temperature 

changes of ice water over time. 

The addition of rock salt to 

water lowers the freezing point, 

yet continued melting of the 

ice results in plummeting water 

temperatures. This activity can 

be used for a variety of lessons, 

the simplest of which would be 

to have the students collect data 

that can be plotted with a line graph. 

However, this can also be utilized to 

introduce students to the concepts of 

endothermic and exothermic reactions, 

and the energy transfer that 

accompanies phase changes of water. 

Activity Introduction: 

plot their group’s data. Discuss why 

the addition of salt causes the water 

temperature to fall below 0 °C. 

Assessment: 

Here are a couple of questions that 

the students should be able to answer: 

• Based on your graph, describe the 

Background 

Concepts: 

At 0 °C, the rate of melting and freezing 

is equal. This means that as the 

ice is melting, new ice is also forming. 

This process continues indefinitely 

until equilibrium is interrupted. 

Adding salt, which dissolves in the 

water, disrupts equilibrium by interfering 

with the freezing of water molecules. 

Salt does not inhibit melting. 

Ice melts, but refreezes at a lower 

temperature. The addition of salt or 

any other substance, like sugar, will 

also lower the freezing temperature. 

References: 

http://antoine.frostburg.edu/chem/senese/101/solutions/faq/why-salt-meltsice.shtml 

• 



OBJECTIVES: 

How Low Can You Go? 

1. Gather data to determine how salt affects the freezing temperature of water. 

2. Create a line graph showing the data. 


HYPOTHESIS: 

If salt is added to ice water, then______________________________________________________________. 

EXPERIMENT/PROCEDURE: 

1. Carefully read the temperature of the thermometer. Record this on the data table as “Temperature at time 0.” 

2. Fill the beaker full of ice. 

3. Add 50mL of water and IMMEDIATELY place the thermometer into the ice water mixture. 

4. Every 10 seconds, read and record the temperature WITHOUT REMOVING THE BULB OF THE 

THERMOMETER FROM THE MIXTURE! (You can lift the thermometer slightly, but do not take the bulb out of 

the ice water!) 

5. Once the temperature does not change for 20 seconds (2 intervals), add one scoop of rock salt to the mixture and 

gently stir. DO NOT REMOVE THE THERMOMETER! 

6. Continue to read/record the temperature every ten seconds for an additional 60 seconds. 

7. On the data table below, be sure to indicate with an asterisk (*) the time at which you added the salt. 

DATA: 

Time (seconds) Temperature (°C) Time (seconds) Temperature (°C) 

0 

10 

20 

30 

40 

50 

60 

70 

80 

90 

100 

110 

120 

130 

140 

ANALYSIS 


How Low Can You Go? Page 2 

Create a line graph to show your data. Line graphs are used to show how one thing changes in relation to another. 

1. First, determine what data goes on the X axis (the independent variable) and what goes on the Y axis (the 

dependent variable). 

2. Then look at the data and determine the minimum and maximum for each axis. 

3. Label and number each axis. 

4. Graph your data. For this data, you will connect the data points with a straight line. 

(BE SURE TO WORK IN PENCIL and USE A RULER!) 

CONCLUSION: 

Please answer in complete sentences. 

1. Based on your graph, describe the relationship between time and temperature. Is it a direct relationship 

(X increases, Y increases) or an inverse relationship (X increases, Y decreases)? 

2. What effect did adding the salt have on the temperature of the ice water? 

3. Was your hypothesis correct or incorrect? 


EXTRA CREDIT: (3 points) 

Why did the salt affect the temperature of the ice water mixture? 


Seasonal Mathematics 


“Holiday Shopping 

Activity” 


In this fun seasonal activity, students 

review percents by going Christmas 

shopping for their friends and family. 

They will look through catalogs for 

gifts to give and cut out pictures of 

the gifts they choose. Students will 

have to calculate percent off to get the 

item’s sale price and then add tax to 

the item’s price for a final cost. 


Ask students where they see percents 

in the real world. Many will likely 

say they see them when shopping. 

Ask what kind of percents students 

see when shopping. Students should 

include both sales and tax. Tell the 

students that they will be using their 

knowledge of percents to shop for 

presents for their friends and family. 


• To prepare for this activity, bring in 

catalogs or advertisements from the 

newspaper that include items students 

would want to give to friends and 

family for Christmas. 

• Start with the Activity Introduction 

and then have each student pick a gift 

out of their catalogs. At this point, 

you may want to review with the 

students how to calculate a price for 

something that’s on sale for a percent 

off and how to calculate the price of 

an item with tax. 

• Have students tape their choices on 

a piece of paper and list who receives 

their gift and the original price. The 

teacher announces that each item is 

selling at a discount, but is also subject 

to state taxes. Students then calculate 

the price with the sale percent 

and tax percent as given on Item #1. 

• When the students complete the 

calculation for their first gift, tell 

them to raise their hands to have you 

check it. Bring a calculator with you 

if necessary. If the student’s calculated 

price is correct, then have them 

pick a second gift and calculate taxes 

and discounts using the information 

for Item #2. 

• Students should continue to work at 

their own pace through five gifts, or 

as many as they can correctly complete 

within the period. Allow the 

students to “exchange gifts” at the 

end of the period. 

Activity Extension: 

This activity would be more interesting 

and realistic if you gave the 

students a budget they had to follow 

for their five gifts. The budget you 

assign could be $50, $75, or $100. 

Students could also make separate 

gift plans using different budgets. 

Item Pricing: 

Item #1 is on sale for 25% off. The 

item is from Alabama, so there is a 

4% tax on it. 




7th grade math: 7.1 B, 7.2 B, 7.3 A, 

7.13 A 

converting fractions, whole numbers 

and percents, estimating using 

percentages, applying mathematics 

experiences 

Materials List: 

Catalogs 

Giftbox handout 



item is from Mississippi, so there is a 

7% sales tax. 


item is from West Virginia, so there is 

a 6% sales tax. 


item is from Maryland, so there is a 

5% sales tax. 


item is from Kansas, so there is a 

5.3% sales tax. • 

Candace DiBiano presenting her Seasonal Mathematics poster at the National GK- 

12 Conference in Washington, D.C. 


The Great Easter Egg Hunt 



In this activity, the teacher turns the 

classroom into a gigantic coordinate 

plane and places plastic Easter eggs 

at points on the coordinate plane. 

Students in five teams go on an eggto-egg 

scavenger hunt, solving math 

TAKS problems found inside the 

Easter eggs in order to get the coordinates 

for their next point. After going 

through 10 points in this way, the 

hunt is over and a winner is declared. 


To introduce the students to the “rules 

of the hunt,” pass out “The Great 

Easter Hunt” handout to each group 

and go over it with them. Answer 

any questions the students have about 

how the hunt will be run. 


• Because this activity requires a lot 

of preparation, it is recommended that 

An Iola ISD student makes her way through the 

Easter Egg Hunt, using each egg to find the next 

coordinate point. 


you select students to assist you. 

• Begin by purchasing plastic Easter 

eggs and enough sticky-back Velcro 

to attach a small piece to each egg. 

Next, copy a page of TAKS questions. 

The first question will be given 

to each team at the start of the activity. 

The rest of the questions are to be 

hidden inside the eggs. The answer to 

the first question should yield a point, 

which the students must find on the 

grid on the floor. The new egg should 

yield another point, which leads to 

another egg on the floor. Label each 

proceeding question with the point 

given from the previous one. For 

example: 

First question: 

X- The greatest common factor of 12, 

18, and 24. 

Y- The square root of 25. 

Answer: (6, 5) 

The second question should be inside 

an egg at point (6,5). 

Use a separate color of paper for each 

team to minimize confusion when 

coordinate answers occupy the same 

spot. 

• After you’ve copied your TAKS 

questions with their respective coordinate 

points, cut the questions into 

strips to separate the clues for each 

point. At this point, leave the answer 

to the previous question as part of 

your strip to help you as you place the 

eggs on the floor. 

• Put the first question for each team 

in a separate plastic bag, as you will 

simply be handing this clue to them at 

the beginning of the hunt to start them 

out. 

• Now stuff the remainder of the 

horizontal slips into plastic Easter 

eggs. Here is the procedure to use: 

Take the slip you are working with 

and a plastic Easter egg. Cut the strip 

vertically to separate the two questions 

on it from the point where the 




customizable 


• 50-75 plastic, colored Easter eggs 

• enough sticky-back Velcro to put a 

small piece on each Easter egg 

• masking tape 

• (Optional) Easter candy for inside 

eggs and/or for prizes 

Cost per group: $3.00-$5.00 

slip will be located. Put the part with 

the two questions inside the Easter 

egg, and tape the part with the location 

of the question on the outside of 

the Easter egg. 

• When you set up your Easter egg 

coordinate plane, you will know 

where each egg is supposed to go. 

• Many clues for the different team 

colors will have the same coordinate 

point as their location. Simply place 

them into the same egg that is labeled 

with that point. 

• (Optional) Stuff candy inside some 

or all of the eggs. 

• Place the sticky-back Velcro on the 

outside of each egg. The other side 

of the Velcro will be stuck to the floor 

where the coordinate plane grid is, to 

secure the egg to its specific point. 

• The coordinate plane assumes only 

positive points, so you will just be 

making one quadrant. If the floor in 

your classroom has square tiles, you 

can just use the tiles as your coordinate 

plane grid. Otherwise, use masking 

tape and the assistance of students 

to make a coordinate plane grid on 

your floor. In either case, you must 

mark the X and Y axes with tape, and 

labeling every five units is also helpful. 

Your grid should be at least 21 

units in the X direction, and 17 units 

in the Y direction. 

• Once the grid has been built in the

classroom, start placing your eggs at 

the locations they noted on the questions, 

attaching them to the floor with 

the other side of the Velcro. Place the 

egg on its coordinate point. 

• Once you’ve placed all the Easter 

eggs that will be part of the hunt, take 

the remainder of your plastic Easter 

eggs, and put slips of paper that say 

WRONG in them. Place these eggs 

at random positions on the coordinate 

plane. They will serve to confuse 

students so they can’t just “guess” 

which egg will be next. When the 

students come across one of these 

WRONG eggs, they must report it 

to you. If they turn in five WRONG 

slips, they will not be able to win the 

Easter hunt. 

• Now the hunt is ready for the 

students. Divide the class into five 

teams, and give each group “The 

Great Easter Egg Hunt” handout and 

their first clue. You can award an 

Easter prize to the first group that gets 

through all their points as a way of 

encouraging participation. 

Lesson Extensions: 

This lesson can be extended to include 

the negative quadrants of the 

coordinate plane. A revision of the 

questions, to include answers with 

negative numbers, can be made to accomplish 

this. • 

The Great Easter Egg Hunt 

Student Handout: 

The classroom has been divided into a gigantic coordinate plane, with each floor tile being one space 

on the grid. 

Your group will be given a starting point, and you will need to find that point on the grid and open the 

colored Easter egg that is there. Take out ONE slip of paper from the Easter egg, the one that has your 

group color on it. You may also take any candy you find. Replace the egg EXACTLY where it was. 

This slip of paper will direct you to your next 

point. However, it should say “(Color) Team, 

Point 2” on it. If your team color is not listed, 

you’ve gone to the wrong point, and you need to 

replace the egg and try again. In 

order to win, you need to have all 

of your group’s paper slips on your 

desk. 

There will also be some 

eggs that just have a slip 

of paper with the word 

WRONG on it. If you find 

one of these, give the slip 

to your teacher and continue 

your hunt. If your 

group gets 5 of these slips of 

paper, you will not be able to 

win the egg hunt. 


Valentine’s Day Hearts 





6th grade math: 6.3 B, 6.12 A 

representing fractions, 

communicating mathematical ideas 


• three or four bags of candy 

“conversation hearts” 

• small Ziploc bags 

Cost per group: $1.00-$3.00 


In this activity, students will use mixes 

of Valentine’s Day candy “conversation 

hearts” to study fractions and 

percents. They will also formulate 

their own mixes of these candies from 

instructions given to them. 

Grade Level: Target Grade: 6 

Time Required: 45 minutes 


Mention to students the upcoming 

holiday, Valentine’s Day, and tell 

them they will be using candy hearts 

to study fractions and percents. 

Preparation: 

The teacher can make each group 

have the same Valentine’s candy mix 

for simplicity, but this activity is 

designed so there are four different 

mixes a group can be given. Label 

each plastic bag with its corresponding 

mix number and fill each with the 

following: 

Mix #1: 10 pink, 8 yellow, 20 orange, 

6 purple, 6 white 








The teacher should also print out two 

Valentine’s task cards for each group 

that corresponds to their mix. They 

are designed to be printed out on 3” 

by 5” index cards, but can simply be 

printed on paper and cut into slips. 

Each group will be given cards that 

correspond to their mix number. 


Divide the students into groups of two 

or three and give each group a plastic 

bag containing their mix. Tell students 

to begin Task 1, using a scratch 

piece of paper to record their work. 

As they complete each task, check 

their answers, and give them instructions 

for the next task. 

TASK CARDS 

Mix #1 Task 2 Mix #2 Task 3 Mix #4 Task 2 

Pink: 2/9 Pink: 28% Pink: 1/4 

Yellow: 1/18 Yellow: 40% Yellow: 1/18 

Orange: 5/9 Orange: 16% Orange: 5/12 

Purple: 1/12 Purple: 4% Purple: 1/9 

White: 1/12 White: 12% White: 1/6 

Total: 36 Candies Total: 25 Candies Total: 36 Candies 

Mix #1 Task 3 Mix #3 Task 3 Mix #4 Task 3 

Pink: 36% Pink: 5/12 Pink: 32% 

Yellow: 24% Yellow: 1/18 Yellow: 12% 

Orange: 16% Orange: 1/36 Orange: 28% 

Purple: 4% Purple: 1/9 Purple: 4% 

White: 20% White: 7/18 White: 24% 

Total: 25 Candies Total: 36 Candies Total: 25 Candies 

Mix #2 Task 2: Mix #3 Task 3 

Pink: 2/9 Pink: 40% 

Yellow: 5/18 Yellow: 12% 

Orange: 5/12 Orange: 20% 

Purple: 1/18 Purple: 4% 

White: 1/36 White: 24% 

Total: 36 Candies Total: 25 Candies 

Task 1: You’ve been given a bag 

with various colors of Valentine’s 

hearts in it, and it’s now your task to 

find the fraction and percentage of 

each color of heart. Each bag contains 

50 hearts. 

Calculate and reduce the fraction of 

each of the following colors: 

pink, yellow, orange, purple, and 

white. Using the fractions, calculate 

the percentage of each color in the 

bag. 

Task 2: Using the candy hearts you 

have, create a mix of 36 candy hearts 

with the ratios given to you on your 

task card. 

Task 3: Using the candy hearts that 

you have, you will need to create a 

mix of 25 total candy hearts with the 

percentages given on your new task 

card. • 

Partnership for Environmental Education and Rural Health Worksheet

Novice Teacher Corner 

Shawn Martin, PEER Teacher 

Novice, beginner, fledgling, rookie, apprentice. No matter how you say it, 

you are a new teacher. You are scared to death and don’t know how to start, 

let alone teach a class full of students. So what do you do? Take a deep 

breath, breathe in, breathe out, and do what you know. Your students will 

come from a variety of backgrounds, economic situations, nationalities, etc. 

It is your job to create a safe, bright spot in their lives where they can relax, 

think and have their creativeness shine through. 

1. Your room needs to be comfortable. 

All of your students need to be comfortable in your classroom. That doesn’t 

mean that you should go out and buy furniture for your room. Just arrange it 

so that students are the focus. 

2. Your classroom needs to be a community. 

Make sure that your classroom has rules and consequences. No community 

will work if antisocial behaviors are not addressed. 

3. Your classroom is a learning environment. 

Not everyone learns the same way. You must reinforce each student’s learning 

by allowing multiple learning styles in your classroom. Let each student 

receive recognition for his or her own achievements. 

Once you have developed your classroom home, the learning will take place. 

You will have a classroom full of learners who show respect for each other, 

who celebrate individualism, and who are open to thinking outside the box. 

For novice teacher help: 

e-Mentoring and the GK-12 Program 

One of the concerns of any teacher is where to get 

answers to sometimes difficult questions. PEER offers 

a variety of pedagogical resources through our website’s 

e-Mentoring initiative, found at http://peer.tamu. 

edu/Mentoring.htm. Our goal is to provide a support 

system for all pre-service and novice teachers, as well 

as for those who have been teaching for a while. 

Last-Minute Tips 

One of the hardest things about 

teaching is the first year. Whether 

it’s your “first” first year or the first 

year in a new school, things will go 

wrong! I recently asked a group of 

veteran teachers, “If you could give 

novice teachers one piece of advice, 

what would it be?” After much 

laughing, crying, and story-telling, 

we compiled a list of the top 10 survival 

skills for the first-year teacher. 

1. Remember to ask for help! You 

can’t do it all, all by yourself. 

2. Make sure you have a good discipline 

plan and follow it. 

3. Be firm with students and parents. 

4. Contact parents often. 

5. Be flexible. 

6. Don’t sweat the small stuff; prioritize. 

7. Surround yourself with friends! 

8. Become a lifelong learner. 

9. Don’t take everything personally. 

10. Don’t try to save the world your 

first year! 

Through this website we offer: a free service for requesting 

custom lesson plans, activities, and answers 

to content questions; free access to informational 

resources for new teachers, including articles, tip 

sheets, and links; free online interviews with scientists 

and educators to share with your students; free online 

web curricula; and the opportunity to request the free 

PEER curriculum, which integrates science, math, 

social studies and English content using adventure 

stories and PowerPoint presentations. • 

Shawn Martin presents strategies for integrating curricula at a teacher 

workshop. 


Visit peer.tamu.edu for 

free educational curricula. 

• Mini-modules (one-class, self-contained 

lessons) 

• Free CDs containing all of PEER’s 

curricula 

• Adventure-based health science story 

lessons that incorporate math, science, 

social studies, and language arts 

• Online mentoring for novice teachers 

• Professional sessions across Texas 

• Distance Learning Community 

• Web curricula on life science and 

environmental health

Appendix C 

IFT Bylaws

AMENDED BYLAWS OF THE FACULTY OF TOXICOLOGY 

OF TEXAS A&M UNIVERSITY 

Article I: Description 

The Faculty of Toxicology at Texas A&M University is an interdisciplinary faculty representing 

member departments in several colleges, other on-campus laboratories, and collaborating scientists from 

other institutions. 

Article II: Purpose and Intent 

The major function of the Faculty of Toxicology is the administration of graduate programs 

leading to the Master of Science and Doctor of Philosophy degrees in Toxicology, in conformance with 

the rules of the Office of Graduate Studies of Texas A&M University. The organization will provide 

leadership for those activities and functions which are critical for the development and growth of a 

research and training program which will be nationally recognized in this important area of the biomedical 

sciences. These activities will include: the development of academic courses which will provide a broad 

background in this discipline; a toxicology seminar program; the preparation of a brochure which can be 

used for recruitment of graduate students; and the development of forums for Toxicology faculty/student 

interactions (i.e., regional and local symposia/conferences; student seminars). Graduate students in this 

program will receive the M.S. or Ph.D. in Toxicology but will be affiliated with the home department of his 

or her graduate advisor. The program will be administered fiscally in the Department of Veterinary 

Physiology and Pharmacology. 

Article III: Membership 

The Faculty of Toxicology shall consist of members of the Graduate Faculty who are qualified to 

direct the research of candidates for the M.S. and Ph.D. degrees. Admissibility shall be determined by a 

vote of the majority of the Executive Committee after nomination of the candidate by other faculty 

members. Visiting Graduate Faculty from other laboratories or institutions not directly associated with 

Texas A&M University shall be nominated and approved using the same criteria applied to on-campus 

faculty. 

Associate Members of the Faculty of Toxicology shall consist of Texas A&M University faculty 

members whose research interests are related to toxicology. Admissibility shall be determined by a vote 

of the majority of the Executive Committee after nomination of the candidate by other faculty members. 

Article IV: Executive Committee 

1. The Executive Committee shall consist of six persons elected from the members of the Faculty of 

Toxicology. In addition, one elected graduate student will serve on the Executive Committee as a 

non-voting member. 

2. The Executive Committee faculty members shall be elected by the members at large and the 

graduate student shall be elected by the students enrolled in the M.S. and Ph.D. programs in 

toxicology. 

3. Members of the Executive Committee shall serve for three years with a predetermined number 

standing for reelection each year. 

4. The Chair and Vice-Chair of the Executive Committee will be elected by the Executive Committee 

from the membership of the Executive Committee and will serve two year terms. They are subject to 

reelection by the Executive Committee at the end of their terms. Any vacancies that occur in the 

membership of the Executive Committee between elections will be filled through an appointment by a 

majority of the Executive Committee.

5. The Chair shall be the chief officer and spokesperson for the Faculty and shall appoint, with approval 

of the Executive Committee, the chair and other members of standing committees and special 

committees. 

6. The Vice-Chair shall serve as chief officer of the Faculty of Toxicology in the absence of the Chair or 

when designated by the Chair. 

Article V: Election to the Executive Committee 

1. A nominating committee composed of three members shall be elected by the Executive Committee 

prior to the annual meeting. At least one member of the nominating committee shall not be a member 

of the Executive Committee. 

2. The Nominating Committee will recommend one or more candidates for each vacant position on the 

Executive Committee. Further nominations may be made from the floor at the annual meeting of the 

Faculty of Toxicology. 

3. The Executive Committee will solicit nominations for the graduate representative from the graduate 

students and all the nominees will be placed on the ballot. The candidate who receives the most 

votes will be declared elected. 

4. Elections to the Executive Committee will be conducted by ballot to be distributed to all Toxicology 

Faculty after the annual Faculty of Toxicology meeting before the end of the Fall semester. Each 

member shall vote for no more candidates than the number of positions to be filled. Those persons 

receiving the greatest number of votes will be declared elected. Election results shall be mailed to 

the members promptly. Elected members shall assume their duties on the day following the last 

class day of the Fall semester. 

Article VI: Functions of the Executive Committee 

1. The members of the Executive Committee will represent the individual members of the Faculty of 

Toxicology and implement policy and decisions that will enhance academic and research excellence 

in Toxicology. 

2. The Executive Committee will administer and coordinate all aspects of the M.S. and Ph.D. graduate 

programs, including the development of a core course curriculum in Toxicology and interaction with 

Department Heads regarding teaching assignments. 

3. The Executive Committee will establish criteria for and rule on admission of all graduate students into 

the program, coordinate the rotation of students in faculty laboratories and administer funding 

available for scholarships/rotations. 

4. The Executive Committee will set academic and research guidelines for admission to the Faculty of 

Toxicology. 

5. The Executive Committee will also develop guidelines for the development of training grant proposals 

which will be submitted to federal and state agencies. 

6. The Executive Committee will be responsible for all other activities deemed necessary for proper 

function of the Faculty of Toxicology. 

Article VII: Functions of the Chair 

The Chair is the representative of and spokesperson for the Executive Committee and the Faculty of 

Toxicology. His or her primary responsibility is the execution of those administrative functions of the 

Toxicology Program. The Chairperson will:

1. Chair the Executive Committee and meetings of the Faculty of Toxicology. 

2. Provide leadership in short- and long-term planning for the program, represent the Faculty of 

Toxicology in College and University meetings as appropriate and develop appropriate contacts with 

industry and institutions outside the University community. 

3. Assure the coordination of graduate student recruitment and develop liaison and exchanges with 

other undergraduate biomedical science departments in the region. 

4. Work closely with Heads of Departments to secure graduate stipend support for students in the 

program. 

5. Approve degree programs, petitions, theses and dissertations for toxicology graduate students. 

6. Recommend the budget and approve expenditures for the Faculty of Toxicology. 

Article VIII: Meetings 

1. The annual meeting of the Faculty of Toxicology will be held by the end of the Fall semester. 

2. A regular meeting of the Executive Committee will be held each fall and spring semester. Other 

meetings of the Executive Committee may be held as required and for such purposes as are deemed 

desirable by the Executive Committee. 

3. The minutes of each Faculty and Executive Committee meeting will be distributed to all members of 

the Faculty of Toxicology within three weeks after approval by the Executive Committee. 

4. A quorum for Executive Committee meetings will consist of four members of the Committee. Twentyfive 

percent of the members will constitute a quorum for meetings of the Faculty of Toxicology. 

Article IX: Standing Committees 

The members of each standing committee shall be appointed prior to July 1 of each year and shall serve 

from December 1 through November 30 of the following year. 

1. Committee on Graduate Programs 

The Committee on Graduate Programs will review and advise the Executive Committee on the graduate 

course curriculum and initiate the development of new graduate courses. This committee will also serve 

to screen applicants for admission to the graduate program and review the progress of current graduate 

students. The Chair or his/her designee, at least one member of the Executive Committee, and additional 

faculty members as appropriate will serve on this committee. 

2. Committee on Seminars/Symposia/Conferences 

The Committee on Seminars/Symposia/Conferences will organize the Toxicology Seminar Program and 

will inform and encourage faculty and students to attend and participate in appropriate regional and 

national scientific meetings. This committee will also serve to receive and screen applications for student 

travel awards. At least one of the members of this committee will be a member of the Executive 

Committee. 

3. Committee on Membership 

Nominations of faculty members to the Faculty of Toxicology will be made to the Executive 

Committee by a current member of the Toxicology faculty and should include the proposed member’s

curriculum vitae. Membership of the Faculty of Toxicology shall be conferred by a majority vote of the 

Executive Committee. The Executive Committee will review on a yearly basis the list of members and 

their current eligibility. 

Article X: Amendments 

Proposed amendments to the Bylaws shall be submitted to the members of the Faculty of 

Toxicology for approval or disapproval following either: (1) approval of a motion to do so by two-thirds of 

the Executive Committee or (2) written petition to the Executive Committee by a minimum of twenty-five 

percent of the Faculty of Toxicology. Approval by two-thirds or more of the Faculty of Toxicology 

members is required to adopt proposed amendments. Amendments will be considered at the annual 

meeting of the Faculty of Toxicology and members will be informed of all proposed amendments at least 

two weeks prior to this meeting. 

Bylaws Approved March 5, 1990 

Amended February 22, 1995 

January 12, 1996

Appendix D 

Duties of Administrative Assistant

IFT Program Assistant Job/Duty Description 

Graduate student advisor. Prepare official correspondence and petitions for graduate students, 

assist in scheduling preliminary exams and defenses, maintain student records and track 

student progress. Advise students on course registration. 20% 

Facilitating application process by updating applicant files, tracking application status, 

distributing applicant profiles to faculty, arranging final acceptance meetings, and overseeing 

choice of final PI laboratories for the students. This requires frequent correspondence with 

departmental administrators and the admissions office as well as fiscal office to assure funding 

sources for all students. 5% 

Coordinate Toxicology Seminar Series, fall and spring semesters; help in contacting and inviting 

prospective speakers, prepare and distribute announcements, assist speakers in arranging 

travel, prepare speaker itineraries and reimbursement vouchers. 15% 

Provide administrative support for the NIEHS Toxicology Training Grant. Duties include 

preparation of appointment and termination forms, overseeing financial records, preparation of 

competitive renewals and annual progress reports and other official correspondence with 

NIEHS. Prepare tuition and medical insurance reimbursements and track spending of trainee’s 

research support funds. 10% 

Make travel arrangements and process vouchers for approximately 50 students, staff and 

faculty for two major conferences per year and some travel arrangements for smaller 

conferences throughout the year. 10% 

Provide a portion of the administrative support for the NIEHS Superfund Basic Research 

Program. Assist in preparation of grant renewals, progress reports, newsletters, and sponsored 

conferences, correspond with NIEHS, and oversee finances of the off-campus subcontract and 

student training portions of the grant. 25% 

Recruit Ph.D. students for the interdisciplinary program. 5% 

Prepare and distribute IFT newsletter. 2.5% 

Supervise student worker. 5% 

Serve as back-up administrator for the NIEHS Center for Environmental and Rural Health. 

2.5%

Appendix E 

IFT Seminar Series 

1998-Present

Spring 2007 

Toxicology Seminar Schedule 

Mondays, 11:30 AM – 12:20 PM 

Room 210, Veterinary Medical Sciences Building (VMS) 

Jan. 22 

Thomas J. Kuehl, MD, Scott & White Division of Research 

“Potential Role of DAZ and DAZ-like Genes in Control of Human Spermatogenesis” 

Co-Sponsored by the Center for Environmental and Rural Health 

Host: Phil Mirkes 

Jan. 29 Bruce Duncan, PhD, U.S. Environmental Protection Agency, Region 10 

“Using Toxicity Data in Ecological Risk Assessments at Contaminated Sites“ 

Host: K.C. Donnelly 

Feb. 5 

Larysa Pevny, PhD, UNC Neuroscience Center, Genetics, Univ. of North Carolina-Chapel Hill 

“SOX2 Functions to Maintain Neural Progenitor Identity in the Central Nervous System“ 

Host: Rick Metz 

Feb. 12 Weston Porter, PhD, Veterinary Integrative Biosciences, Texas A&M University 

“The Molecular Clock in Mammary Gland Development and Breast Cancer” 

Host: Dr. Burghardt 

Feb. 19 Clinton D. Allred, PhD, Dept. of Nutrition and Food Science, Texas A&M University 

“Nuclear Receptors as Molecular Targets of Dietary Compounds in Cancer Cells” 

Host: Bob Burghardt 

Feb. 26 Gary H. Perdew, PhD, Ctr for Molecular Toxicology & Carcinogenesis, Penn State University 

4:00 PM "Modulation of Ah receptor-mediated transcription by the estrogen receptor and the role of the 

2004 SAC AhR in inflammatory signaling” 

Host: Yanan Tian 

Mar. 5 

Mar. 19 

Apr. 2 

Apr. 9 

Apr. 16 

Apr. 23 

Joseph M. Betz, PhD, Office of Dietary Supplements, National Institutes of Health 

“Dietary Supplements and Functional Foods in a Global Marketplace: Scientific and Regulatory 

Perspectives” 

Host: Suzanne Talcott 

Yuri Gorby, PhD, J. Craig Venter Institute 

“Bacterial nanowires: Extracellular electron transfer and energy distribution” 

Host: Suresh Pillai 

Kohei Shiota, PhD, Kyoto University Graduate School of Medicine, Kyoto, Japan 

“Teratogenesis of Holoprosencephaly: Interplay of Genetic and Environmental Factors“ 

Host: Phil Mirkes and Hiromi Hosako 

Aron B. Fisher, MD, Inst for Environmental Medicine, Univ of Pennsylvania Medical Center 

“Peroxiredoxin 6, a Bi-Functional Enzyme with Important Roles in the Anti-Oxidant Defense and 

Phospholipid Metabolism” 

Host: Shashi Ramaiah 

Kung-Hui Chu, PhD, Department of Civil Engineering, Texas A&M University 

Title to be announced 

Host: Dr. Donnelly 

Arthur Frankel, MD, Scott & White Cancer Center and Cancer Research Inst. 


Co-Sponsored by the Center for Environmental and Rural Health 

Host: Dr. Mirkes

Fall 2006 


Mondays, 11:30 AM – 12:20 PM 


Sept. 11 

Sept. 18 

Sept. 25 

Oct. 2 

Oct. 9 

Marina Guizzetti, PhD, Univ. of Washington, Environmental & Occupational Hlth 

“Ethanol Effects on Cholinergic System in Astrocytes: Relevance for Fetal Alcohol 

Syndrome” 

Host: Dr. Steve Safe 

Shaoyu Chen, PhD, Univ. of North Carolina, Dept. of Cell and Developmental Biology 

“From Living Cell Confocal Microscopy to Proteomics: Innovative Approaches to 

Studying the Mechanisms” 


Seung Jun Baek, PhD, University of Tennessee, Department of Pathobiology 

“Gene Alterations by PPARγ Ligands” 


Hide Tsukamoto, DVM, PhD, USC Cirrhosis Research Center 

“Fat Paradox of Chronic Liver Disease” 

Host: Dr. Shashi Ramaiah 

Yu-An Cao, PhD, Stanford University School of Medicine, Department of Pediatrics 

“Heme Oxygenase 1 Deficiency Compromises Stress Responses of Hematopoietic Stem 

Cells” 


Oct. 16 Gary H. Perdew, PhD, Penn State Univ., Ctr for Molecular Toxicology & Carcinogenesis 

*4:00 PM* "Modulation of Ah receptor-mediated transcription by the estrogen receptor and the role 

2004 SAC of the AhR in attenuation of inflammatory signaling" 

Host: Dr. Yanan Tian 

Oct. 23 

Oct. 30 

Nov. 6 

Nov. 13 

Nov. 20 

Nov. 27 

No Seminar 

Wei Zheng, PhD, Purdue Univ. Sch. Health Sciences, Health Sciences and Toxicology 

“Diagnosis and Treatment of Manganese Parkinsonims: Bed, Bench and Beyond” 

Hosts: Dr. Evelyn Tiffany-Castiglioni and Yongchang Qian 

Colin R. Jefcoate, PhD, University of Wisconsin Madison, Dept. of Pharmacology 

“Physiological and toxicological roles of cytochrome P450 1B1” 


Geoffrey Curtin, PhD, R.J. Reynolds Tobacco Company 

“Rodent Models for Evaluating Tobacco Smoke Toxicity” 


Oliver Hankinson, PhD, UCLA, Dept. of Pathological & Laboratory Medicine 

“Role of the Aryl Hydrocarbon Receptor in Transcription and Cancer” 


Thomas K. Wood, PhD, TAMU Chemical Engineering, Biology & Civil Engineering 

“Deciphering Cell Signaling in Bacterial Biofilms: The Role of Indole” 

Host: Dr. Steve Safe

Spring 2006 


Mondays, 11:30 AM – 12:20 PM 


Jan. 30 

Feb. 6 

Feb. 13 

Feb. 20 

Feb. 27 

Mar. 6 

Mar. 13 

Mar. 20 

Mar. 27 

Apr. 3 

Apr. 10 

Apr. 17 

Apr. 24 

May 1 

May 8 

Robert W. Biles, PhD, Senior Toxicology Advisor, ExxonMobil Biomedical Sciences 

“Toxicology/Health Science at ExxonMobil Biomedical Sciences- Issues and Careers” 

Host: Christine Naspinski 

Robert M. Greene, PhD, Molecular, Cellular & Craniofacial Biol., Univ. Louisville Sch. of Dentistry 

“Integrated Signal Transduction: The Language of the Embryo" 

Host: Dr. Philip Mirkes 

Hans Schuessler, PhD, Dept. of Physics, Texas A&M University 

“Biomolecules in Vitro and in Silico” 

Host: Dr. Bob Burghardt 

No Seminar 

Curtis Klaassen, PhD, Pharmacology, Toxicology & Therapeutics, Univ. of Kansas Medical Center 

“Nuclear Receptor Regulations of Rat Hepatic Transporters” 


**Co-Sponsored by the Center for Environmental and Rural Health** 

No Seminar – Society of Toxicology 45 th Annual Meeting 

No Seminar – Spring Break 

Douglas M. Cerasoli, PhD, U.S. Army Medical Research Institute of Chemical Defense 

“Butyrylcholinesterase and Paraoxonase I - Development of Bioscavengers for Protection Against 

Organophosphorus Nerve Agents" 

Host: Dr. Jim Wild 

Mark Robson, PhD, MPH, ATS, Environmental & Occupational Hlth, UMDNJ-School of Public Hlth 

“Challenges and Opportunities for International Environmental Health Research” 

Host: Dr. KC Donnelly 

No Seminar 

Monique Rijnkels, PhD, Children’s Nutrition Research Center, Baylor College of Medicine 

“Milking the Genome: Evolution and Regulation of the Casein Gene ClusterRegion” 

Host: Dr. Weston Porter 

Seung J. Baek, PhD, Dept of Pathology, University of Tennessee 

“Chemoprevention and NSAID Activated Gene (NAG-1)” 


Janice Chambers, PhD, Center for Environmental Health Services, Mississippi State University 

“OP Insecticides and Developing Systems: How Do We Protect the Children?” 

Host: Dr. Evelyn Tiffany-Castiglioni 

Carey Pope, PhD, Physiological Sciences, Center for Vet. Health Sciences, Oklahoma State Univ. 

"Modulation of Organophosphate Toxicity" 


David Sherr, PhD, Dept. of Environmental Health, Boston University 

"The AhR and CYP1B1 in cancer...What are they good for?" 


Fall 2005 


Mondays, 11:30 AM – 12:20 PM 


Oct. 3 

Oct. 10 

Oct. 17 

Oct. 24 

Oct. 31 

Nov. 7 

Nov. 14 

Nov. 21 

Nov. 28 

Dec. 5 

Dec. 12 

Mark Canfield and Peter Langlois, Birth Defects Epidemiology and Surveillance, TX Dept. of 

State Health Services 

“Birth Defects Surveillance and Research” 

Host: Philip Mirkes 

Kaylee Schwertfeger, PhD, Molecular and Cellular Biology, Baylor College of Medicine 

“Early FGFR Mediated Induction of the Inflammatory Response in Breast Cancer Progression” 

Host: Weston Porter 

Edgar C. Kimmel, PhD, US Army Edgewood Chemical and Biological Center, Aberdeen 

Proving Ground 

“Aerosols and the Respiratory Tract: A Review of the Fundamentals” 

Host: Cody Wilson 

Shawn Bratton, PhD, Dept. of Pharmacology, University of Texas at Austin 

“Inhibitor of Apoptosis (IAP) Proteins and Their Antagonists in Caspase-Dependent Apoptosis” 


John Fackler, PhD, Department of Chemistry, Texas A&M University 

Heavy Metal and Other Inorganic Pollutants, Medicines and Poisons Used in Murder 

Host: Tim Phillips 

Marni Bekkedal, PhD, Wisconsin Bureau of Environmental and Occupational Health 

"Hazards, Exposures, and Health Effects: Why Public Health Needs Toxicologists" 


George Stoica, PhD, Department of Veterinary Pathobiology, Texas A&M University 

“Endogenous Neurotrophin: A Sword With Two Edges” 

Host: To be determined 

Bhagavatula Moorthy, PhD, Baylor College of Medicine, 

"Regulation of Cytochrome P4501A Enzymes by Hyperoxia: Mechanistic Implications for 

Hyperoxic Lung Damage" 


Ursula Winzer-Serhan, PhD, Neuropharmacology, Texas A&M Health Science Center 

“Nicotine, Nicotinic Receptors and Development” 

Host: Louise Abbott 

Yanming Wang, PhD, Biochemistry & Molecular Biology, Pennsylvania State University 

“Histone Methylation in Gene Expression and Cancer Epigenetics” 


Hartmut Jaeschke, PhD, Liver Research Institute, University of Arizona 

“New Insight Into the Molecular Mechanisms of Drug Hepatotoxicity” 

Host: Shashi Ramaiah

Spring 2005 


Mondays, 11:30 AM – 12:20 PM 


Jan. 24 

Jan. 31 

Feb. 7 

Feb. 21 

Feb. 28 

Mar. 14 

Mar. 28 

Apr. 4 

Apr. 11 

Apr. 18 

Larry Johnson, PhD, Veterinary Integrative Biosciences, Texas A&M University 

“Public school - higher education interface: value of involving your graduate students and yourself” 


Paul A. White, PhD, Safe Environments Program, Health Canada 

“The Population-level Impact of Genotoxic Substances in Aquatic Systems” 


Thomas B. Knudsen, PhD, Molecular, Cellular and Craniofacial Biology, University of Louisville, 

School of Dentistry 

"Computational Systems Analysis of Developmental Toxicity" 


Steven G. Gilbert, PhD, DABT, Director, Institute of Neurotoxicology and Neurological Disorders 

"A Small Dose of Toxicology - Health Effects of Common Chemicals” 

Host: Larry Johnson 

Chao-Yin Chen, PhD, Dept. of Medical Pharmacology & Toxicology, University of California-Davis 

“Mechanisms Underlying Cardiovascular Consequences of Particulate Matter Exposure” 

Host: Gladys Ko 

Patrick Grant, PhD, Lawrence Livermore Natl Labs, Center for Accelerator Mass Spectrometry 

“Nuclear Microprobe Capabilities Applied to Metalloproteomics and Other Examples” 


Arul Jayaraman, PhD, Dept. of Chemical Engineering, Texas A&M University 

“Molecular Analysis of Inflammatory Diseases: Towards Development of a Living Cell Array” 


Nasser H. Zawia, PhD, School of Pharmacy, Rhode Island University 

“Sp1 and Amyloidogenesis in the Aging Brain” 

Host: Maen Abdelrahim 

John Lemasters, MD, PhD, Cell and Developmental Biology, Univ. of North Carolina at Chapel Hill 

“Alterations of Mitochondrial Membrane Permeability in Pathogenesis” 


Cole W. Matson, PhD, Dept. of Wildlife and Fishery Sciences, Texas A&M University 

“Combining Environmental Chemistry, Somatic Biomarkers and Evolutionary Toxicology: Wildlife 

Ecotoxicology in the Heavily Contaminated Industrial Zone of Sumgayit, Republic of Azerbaijan” 

Host: John Bickham 

Apr. 22 Elisabeth Christians, PhD, Centre de Biologie du Development, Toulouse, France 

Friday, 11 AM “Life without Heat Shock Factors: From Stress Response to Maternal Effect Mutation and Beyond” 

423 VMRB Cosponsored by the Center for Environmental and Rural Health Host: Philip Mirkes 

Apr. 25 

Cheryl L. Walker, PhD, U.T. M.D. Anderson Cancer Center, Science Park Research Division 

“Developmental Programming of Tumor Suppressor Gene Penetrance: Understanding How Early 

Life Environmental Exposures Can Determine Cancer Incidence in Adults” 


Apr. 26 Louis J. Guillette, Jr., PhD, University of Florida 

Tuesday, 4 PM “Alligators and Contaminants: From Populations to Genes” 

201 VMS Keynote Address for the CVM GSA Research Symposium (Co-Sponsored by Toxicology) 

May 2 

Larry Claxton, PhD, United States Environmental Protection Agency 

“Scientific Authorship: Abuses, Problems and Solutions” 

Host: K.C. Donnelly

Fall 2004 

Toxicology Seminar Series 

Mondays, 11:30 AM – 12:20 PM 


Sept. 20 

Sept. 27 

Oct. 4 

Oct. 11 

Oct. 18 

Oct. 25 

Nov. 1 

Nov. 8 

Nov. 15 

Nov. 22 

Nov. 29 

Rajesh C. Miranda, PhD, Human Anatomy & Medical Neurobiology, TAMUS Health Science Center 

“Nature vs. Nurture: Competing Influences Shape the Differentiation Program in Neural Stem Cells” 

Host: Steve Safe 

Gladys Y.-P. Ko, PhD, Veterinary Integrative Biosciences, TAMU 

“Circadian Regulation of Ion Channels in Retina Cone Photoreceptors - The Story is Still Unfolding” 

Host: Evelyn Tiffany Castiglioni 

Philip A. Philip, MD, PhD, Karmanos Cancer Institute, Wayne State University 

“Translational Research in Pancreatic Cancer” 


Walter C. Prozialeck, PhD, Dept. of Pharmacology, Midwestern University 

“The Cadherin/Catenin Complex as a Molecular Target of Cadmium Toxicity” 

Host: Alan Parrish 

James W. Simpkins, PhD, Pharmacology & Neuroscience, Univ. of North Texas Health Science Center 

“The Neuroprotective Effects of Estradiol and Related Compounds” 


No Seminar 

Vanessa Sperandio, PhD, Microbiology, U.T. Southwestern Medical Center 

“Bacteria-Host Communication: The Language of Hormones” 

Host: Suresh Pillai 

Stuart Shalat, PhD, Environmental and Occupational Medicine, Robert Wood Johnson Medical School 

“Exposure Epidemiology: The Role of Behavior as a Determinant of Dose” 


David Earnest, PhD, Human Anatomy & Medical Neurobiology, TAMUS Health Science Center 

“Tick-Tox: Interactions Between the Mechanisms for Circadian Rhythmicity and Toxin Metabolism” 


Mike Lewis, PhD, Dept. of Molecular and Cellular Biology, Baylor College of Medicine 

“Hedgehog Signaling in Breast Development and Cancer” 


Alice Villalobos, PhD, Dept. of Environmental Medicine, University of Rochester Medical Center 

“Metal-Induced Changes in Transport by Choroid Plexus” 

Host: Kim Daniel 

Dec. 3 Dean Tang, PhD, Carcinogenesis, University of Texas M.D. Anderson Cancer Center-Science Park 

Friday “Prosurvival Mechanisms During Apoptosis” 

423 VMRB Host: Yanan Tian 

Dec. 6 

Tom Jerrells, PhD, Pathology and Microbiology, University of Nebraska Medical Center 

“Viral Infections as Cofactors for Alcoholic Liver Disease and Alcoholic Pancreatitis” 

Host: Shashi Ramaiah

Spring 2004 


Mondays, 11:30 AM – 12:20 PM 


Jan. 26 

Eric Simanek, Ph.D., Chemistry, Texas A&M University 

“Dendrimers Based on Melamine: Synthetic Organic Chemistry Applied to Drug Delivery” 


Feb. 6 

Laurence McCullough, Ph.D. Center for Ethics and Health Policy, Baylor College of Medicine 

3:30 PM, Fri “Scientific and Medical Ethics” 

123 Kleburg Host: Dr. Larry Johnson 

*Co-Sponsored by the Reproductive Biology Forum* 

Feb. 16 

Feb. 23 

Mar. 1 

Mar. 8 

Mar. 15 

Mar. 22 

Mar. 29 

Apr. 5 

Apr. 12 

C. Wayne Smith, M.D., Pediatrics Leukocyte Biology, Baylor College of Medicine 

“Endotoxin and Liver Injury“ 


Wen Xie, M.D., Ph.D., Center for Pharmacogenetics, University of Pittsburgh 

"Orphan Nuclear Receptor-Mediated Genetic and Pharmacological Regulation of Drug 

Metabolizing Enzymes" 


No Seminar 

Robin Fuchs-Young, Ph.D., Carcinogenesis, UT MD Anderson Cancer Ctr-Science Park 

“Contributions of the Estrogen Receptor to Mouse Mammary Tumorigenesis: New Insights from 

Transgenic Models” 


Spring Break – No Seminar 

Society of Toxicology Annual Meeting – No Seminar 

Weston Porter, Ph.D., Veterinary Anatomy & Public Health, Texas A&M University 

“A Singleminded look at Down's Syndrome and Breast Cancer” 


Thomas E. Spencer, Ph.D., Animal Science, Texas A&M University 

“Crystals and Viruses in the Uterus and Placenta: Are Ewe Excited?” 


Timothy F. Osborne, Ph.D., Molecular Biology & Biochemistry, University of California-Irvine 

“SREBPs and Nuclear Receptors: Key Metabolic Sensors that Integrate Lipid Regulation” 


Apr. 20 David Cragin, Ph.D., The Merck Company 

1:00 PM, Tues “Toxicology in the Headlines: Separating Fact from Fiction” 

423 VMRB Host: Dr. K.C. Donnelly 

Apr. 26 

Jane Welsh, Ph.D., Veterinary Anatomy & Public Health, Texas A&M University 

“How Stress Affects Susceptibility to Infections and Autoimmune Diseases” 


Apr. 30 Phil Senger, Ph.D., Animal Science, Washington State University 

3:30 PM, Fri “For Instant Understanding: The Eyes Have It!!” 

123 Kleburg Host: Dr. Larry Johnson 

*Co-Sponsored by the Reproductive Biology Faculty* 

May 3 

Burhan I. Ghanayem, Ph.D., Pharmacology & Chemistry, National Toxicology Program, NIEHS 


Host: Maen Abdelrahim

Interdisciplinary Faculty of Toxicology - Fall 2003 Seminar Series 

Mondays at 11:30 AM - Room 210 Veterinary Medical Sciences Building 

Sept. 8 

Sept. 15 

Sept. 22 

Sept. 29 

Oct. 6 

Oct. 13 

Oct. 20 

Oct. 27 

Nov. 3 

Nov. 10 

Nov. 17 

Nov. 24 

Dec. 1 

Dec. 8 

Frank F. Bartol, Ph.D., Cellular & Molecular Biosciences Program, Auburn University 

“Uterine Patterning and Environmental Programming” 

Host: Dr. Nancy Ing 

*Co-Sponsored with Reproductive Biology Forum* 

No Seminar 

Patricia B. Hoyer, Ph.D., Department of Physiology, University of Arizona 

“4-Vinylcyclohexane Diepoxide: A Model for Ovarian Toxicity“ 

Host: Dr. Alan Parrish 

Rajesh Miranda, Ph.D., Dept. of Human Anatomy and Medical Neurobiology, College of 

Medicine, TAMUS HSC 

“Cell-Fate Determination in the Developing Central Nervous System” 

Host: Dr. Ron Tjalkens 

Gavin E. Arteel, Ph.D., Department of Pharmacology & Toxicology, University of Louisville 

Health Science Center 

“Oxidants and Antioxidants in Alcoholic Liver Disease: Studies with Enteral Rodent Models” 


Susan Fisher-Hoch, M.D., Biological Sciences, University of Texas School of Public Health in 

Brownsville 

“Ebola and Lassa Hemorrhagic Fevers, Viruses that Cause these Diseases, and Some Reasons 

Why They ‘Emerge’” 

Host: Dr. K.C. Donnelly 

Susan R. Rittling, Ph.D., Department of Genetics, Rutgers University 

“Osteopontin as a Tumor and Host Factor in Tumorigenesis” 


Jonathan B. Ward, Jr., Ph.D., Dept. of Preventive Medicine & Community Health, Univ. of Texas 

Medical Branch 

“Investigating Human Sensitivity to Butadiene Using Biomarkers of Exposure, Effect and 

Susceptibility” 


Richard R. Sinden, Ph.D., Center for Genome Research, Institute of Biosciences and 

Technology, TAMUS HSC 

“Structural and Genetic Gymnastics of Expanding DNA Repeats Associated with Human Disease: 

Trying to Make Molehills Out of Mountains” 


James R. Wild, Ph.D., Dept. of Biochemistry and Biophysics, Texas A&M University 

“From TNT Reductase to Anticarcinogenic Pro-drug Activation: One Enzyme’s Genomic Sense 

of Self” 


Gerald D. Frye, Ph.D., Dept. of Medical Pharmacology & Toxicology, College of Medicine, 

TAMUS HSC 

“GABAA Receptors and Fetal Alcohol Syndrome: Mini Current Events” 


Curt Omiecinski, Ph.D., Center for Molecular Toxicology, Penn State University 

“Genetic Polymorphism and Transcriptional Regulation of the Human Epoxide Hydrolases” 


Jijayanagaram Venkatraj, Ph.D., Dept. of Veterinary Anatomy and Public Health, TAMU 

“Genomic Arrays, Gene Arrays and SNP’s: Technology to ExploreG ene-Environment Interaction” 


No seminar (Dec. 10 - CERH Scientific Symposium: Environmental Adaptation and the 

Circadian Response)

Interdisciplinary Faculty of Toxicology - Spring 2003 Seminar Series 


Jan. 27 

Feb. 3 

Feb. 10 

Feb. 24 

Mar. 3 

Mar. 10 

Mar. 17 

Mar. 24 

Mar. 31 

Apr. 7 

Apr. 14 

Apr. 21 

Apr. 28 

K. C. Donnelly, Ph.D., TAMU, VAPH and TAMUS-HSC, School of Rural Public Health 

“Environmental Health in Older Adults” 

Host: Dr. Tim Phillips 

Yanan Tian, Ph.D., Texas A&M University, Veterinary Physiology & Pharmacology 

“Regulation of Cytochrome P450 1A1 Gene Expression by Ah Receptor and NF-κB: Histone 

Modifications and Elongation Control” 


Charles Miller, Ph.D., Tulane University 

“Chaperones and Aryl Hydrocarbon Receptor Signaling” 


Timothy Phillips, Ph.D., TAMU, Vet. Anatomy & Public Health, and the Center for Food Safety 

“Clay-Based Enterosorbents for Aflatoxins: Historical Perspective, Molecular Mechanisms, Latest 

Discoveries and New Applications” 

Frank Witzmann, Ph.D., IUPUI 

“2D Gel-based Proteomics: Applications in Toxicology” 


No Seminar – Spring Break and Society of Toxicology Annual Meeting 

No Seminar 

Rossanne Philen, M.D., M.S., Centers for Disease Control & Prevention, Epidemiology 

Program Office 

“Epidemic Optic Neuropathy in Cuba – Clinical Characterization and Risk Factors” 


Larry Johnson, Ph.D., Veterinary Anatomy & Public Health, Texas A&M University 

“Scientists in Public School Classrooms: Invitation, Presentation, Expectation and Need” 


Deborah del Junco, Ph.D., School of Rural Public Health, TAMUS Health Science Center 

“Biomarker Studies to Explore Gene-Environment Interactions in Disease Etiology” 


Richard S. Pollenz, Ph.D., Department of Biology, University of South Florida 

“Impact of Ah Receptor Localization on Ah Receptor Degradation and Gene Regulation” 

Host: Dr. Keith Murphy 

Patricia B. Hoyer, Ph.D., Department of Physiology, University of Arizona 

“4-Vinylcyclohexane Diepoxide: A Model for Ovarian Toxicity“ 


Dean Jones, Ph.D., Department of Biochemistry, Emory University 

“Redox Mechanisms in Aging and Age-Related Disease” 

Host: Dr. Emily Wilson 

Tues., May 20 Thomas Badger, Ph.D., Dept. of Physiology & Biophysics, Univ. of Arkansas Medical Sciences 

11:30 AM “Molecular Mechanisms By Which Chronic Ethanol Intake Induces Class 1 ADH and CYP2E1 

Gene Expression” 

Host: Dr. Shashi Ramaiah Co-Sponsored by the Department of Veterinary Pathobiology


Mondays at 12:00 PM - Room 210 Veterinary Medical Sciences Building 

Thurs, Aug. 29 Mary K. Walker, Ph.D., University of New Mexico, Dept. of Pharmacology & Toxicology 

3:00 PM “Role of the AhR in the Cardiovascular System” 

423 VMRB Host: Dr. Ken Ramos 

Fri., Sept. 13 James Martin, Ph.D., TAMUS-HSC, Institute of Biosciences & Technology 

11:00 AM “Pitx2 Function of the Left-Right Asymmetry and Cardiovascular Development” 

423 VMRB Host: Dr. Ken Ramos 

Sept. 16 

Sept. 23 

Sept. 30 

Oct. 7 

Oct. 14 

Oct. 21 

Oct. 28 

Nov. 4 

Nov. 11 

Nov. 18 

Nov. 25 

Dec. 2 

Dec. 9 

Daniel Medina, Ph.D., Baylor College of Medicine, Molecular & Cellular Biology 

“p53 Gene Function, Hormones, and the Origin of Aneuploidy in Mouse Mammary 

Tumorigenesis” 


Scott McKenzie, Ph.D., Texas A&M University, Inst. of Food Science & Engineering 

“Basic Research, Intellectual Property Development, and Commercialization of 

Innovative Discoveries” 


Deborah Cory-Slechta, Ph.D., University of Rochester Medical School 

“Pesticides as Risk Factors for Parkinsonism: Interactions with Age, Genetic 

Background and Gender” 


David Adelson, Ph.D., Texas A&M University, Animal Science and Genetics 

“Bioinformatics Tools for Livestock Genomics at TAMU” 

Host: Dr. Robert Chapkin 

No seminar 

Anne Sweeney, Ph.D., TAMUS-Health Science Center, School of Rural Public Health 

“PCBs and Reproductive Effects” 


Larry Dangott, Ph.D., Texas A&M University, Dept. of Biochemistry & Biophysics 

“The Protein Technologies Laboratory and you; Classical Services and Merging 

Technologies in Proteomics at TAMU” 

Host: Dr. Ken Ramos 

No seminar 

Norbert Kaminski, Ph.D., Michigan State Univ., National Food Safety & Toxicology Ctr. 

“Why is the B Lymphocyte a Sensitive Target for TCDD-Mediated Immune 

Suppression?” 


Pepper Schedin, Ph.D., AMC Cancer Research Institute 

“Adolescent Vitamin A Intake Alters Susceptibility to Mammary Carcinogenesis in the 

Sprague-Dawley Rat” 


Alan Parrish, Ph.D., TAMUS-HSC, College of Medicine, Pharmacology & Toxicology 

“Selective Loss of N-cadherin During Renal Failure 


Charles Miller, Ph.D., Tulane University, School of Public Health & Tropical Medicine 

“Chaperones and Aryl Hydrocarbon Receptor Signaling” 


Jim Bus, Ph.D., Dow Chemical 

“The Meaning of Mechanisms: Implications for the Future of Toxicology” 


For more information, or to request a meeting with a speaker, please contact the Toxicology Offi ce 

at 845-5529 or tox@cvm.tamu.edu.

Interdisciplinary Faculty of Toxicology - Spring 2002 Seminar Series 


*Jan. 18 Herman Saatkamp, Ph.D., Indiana University, School of Liberal Arts 

(Friday, 4 PM “The Hidden Structure of Science and Medicine: Ethics” 

162 Reynolds) Host: Dr. Larry Johnson (Lecture for VAPH 689-600, Special Topics in Scientific Ethics) 

Jan. 21 

Jan. 28 

William Hanneman, Ph.D., Colorado State University, Environmental Health 

“Random Insertional Mutagenesis in Mouse ES Cells: Novel Tools for Toxicological Analysis” 

Feb. 4 

Holiday – No Seminar 

Host: Dr. Evelyn Tiffany Castiglioni 

No Seminar 

*Feb. 12 Charlene McQueen, Ph.D., Univ. of Arizona-Pharmacy, Pharmacology & Toxicology 

(Tuesday, 8:30 “Expression of N-acetyltransferases: Age, Genetics and Genotoxicity” 

162 Reynolds) Sponsored by the Medical Pharmacology and Toxicology Department, TAMUSHSC 

Feb. 18 

Feb. 25 

Mar. 4 

Mar. 11 

Mar. 18 

Mar. 25 

Apr. 1 

Apr. 8 

Apr. 15 

Apr. 22 

Apr. 29 

No Seminar 

David Moore, Ph.D., Baylor College of Medicine, Dept. of Molecular and Cellular Biology 

“Metabolic Regulation by the Xenobiotic Receptor CAR” 


Ross Beier, Ph.D., U.S. Department of Agriculture, Agriculture Research Service 

“Natural Toxicants, Antibodies, Bacteria and Food Safety” 


Spring Break – No Seminar 

Society of Toxicology Annual Meeting – No Seminar 

Carlos Suarez-Quian, Ph.D., Georgetown Medical Center, Dept. of Cell Biology 

“Inducible FGF-Independent Activation of the FGFR in the Mammary Gland Results in 

Increased Lateral Branching and Hyperplasia” 


Candace Strang, Ph.D., Baylor College of Medicine, Neuroscience Division 

“The Role of Voltage Gated Potassium Channel Zinc in Channel Activity” 


Louise Abbott, Ph.D., Texas A&M University, Veterinary Anatomy & Public Health 

“Analysis of Neurodegeneration in the Leaner Mouse Cerebellum” 


Michael Aschner, Ph.D., Wake Forest University School of Medicine 

“Manganese Transport and Mechanisms of Neurotoxicity” 


Tim Zacharewski, Ph.D., Michigan State University, Biochemistry & Molecular Biology 

“Toxicogenomic Assessment of Endocrine Disruptors” 


Serrine Lau, Ph.D., University of Texas at Austin, Pharmacology & Toxicology 

“Integrating Studies in Genetics, Oxidative Damage and Cell Signaling in Chemical Induced 

Nephrocarcinogenicity” 

Host: Dr. Ron Tjalkens


Mondays at 11 AM - Room 2004 Veterinary Medical Teaching Hospital 

Sept. 24 

Oct. 1 

Oct. 8 

Oct. 15 

Oct. 22 

Oct. 29 

Nov. 5 

Nov. 12 

Nov. 19 

Nov. 26 

Dec. 3 

Bryan Welm, Ph.D., Baylor College of Medicine, Dept. of Cell Biology 

“Inducible FGF-Independent Activation of the FGFR in the Mammary Gland Results 

in Increased Lateral Branching and Hyperplasia” 


Carlos Suarez-Quian, Ph.D., Georgetown Medical School, Dept. of Cell Biology 

“Laser Capture Microdissection: A Tool for the Isolation of Cells and Tissues from 

Histological Sections” 


Jeff Rosen, Ph.D., Baylor College of Medicine, Dept. of Cell Biology 

“Steroid Hormone and Local Growth Factor Regulation of Mammary Gland 

Development and Early Breast Cancer Progression” 


Richard Finnell, Ph.D., Institute of Biosciences and Technology, Center for Human 

Molecular Genetics 

“Genetic Regulation of Abnormal Neural Development” 


Jia-Sheng Wang, M.D, Ph.D., Texas Tech University, Environmental Toxicology 

“Molecular Biomarkers for Liver Cancer Studies” 


William Hanneman, Ph.D., Colorado State University, Environmental Health 

“Random Insertional Mutagenesis in mouse ES cells: Novel Tools for 

Toxicological Analysis” 


Nancy Weigel, Ph.D., Baylor College of Medicine, Molecular & Cell Biology 

“Nuclear Receptors as Targets for Inhibition of Prostate Cancer Growth” 


Richard Sinden, Ph.D., Institute of Biosciences & Technology, Center for 

Genome Research 

“DNA Repeats and Human Genetic Disease: Dynamic DNA, Dynamic 

Mutagenesis” 


Emily Wilson, Ph.D., TAMUHSC, College of Medicine, Medical Physiology 

“Regulation of Vascular Smooth Muscle Phenotypes by the Cellular Environment” 


Shiuan Chen, Ph.D., City of Hope – Beckman Research Institute 

“Aromatase, Endocrine Disruptors and Breast Cancer” 


Jorge Piedrahita, Ph.D., Texas A&M University, Veterinary Anatomy & Public 

Health 

“Biomedical Applications of Animal Biotechnology” 

Host: Dr. Ken Ramos

Interdisciplinary Faculty of Toxicology 

~ Spring 2001 Seminar Series ~ 

Jan. 22 

Jan. 29 

March 5 

March 12 

March 26 

April 16 

May 3-4 

May 7 

June 18 

Gabor Huszar, M.D., Yale University School of Medicine 

“Biochemical Markers of Sperm Cellular Maturity in Men: Assessment of 

Reproductive Toxicity” 

Host: L. Johnson 

Paul Comet, Ph.D., Navasota ISD, Chemistry Dept. 

“Value of Pattern Recognition in Natural Product (isoprenoid) Studies” 

Host: T. Phillips 

Kevin Gaido, Ph.D., Chemical Industry Institute of Toxicology 

“Analysis of Altered Gene Profi les in Fetal Rat Testes Exposed to 

Di-n-butylphthalate” 

Host: S. Safe 

Spring Break 

Society of Toxicology National Meeting, San Francisco, CA 

Moiz Mumtaz, Ph.D., Agency for Toxic Substances & Disease Registry 

“Implications of Chemical Mixtures in Public Health Practice” 


Texas Forum on Female Reproduction, Houston, TX 

Andrea Hubbard, Ph.D., University of Connecticut School of Pharmacy 

“Cellular and Molecular Regulating Silica-induced ICAM-1 

Expression in Mice” 

Host: A. Parrish 

Suresh Pillai, Ph.D., Texas A&M University Food Safety & Environmental 

Microbiology 

“The Structural Stability and Biological Activity of Naked Phage 

RNA Molecules in the Environment” 

Host: T. Phillips 

Mondays at 11 AM ~ Room 2006 Veterinary Teaching Hospital

Interdisciplinary Faculty of Toxicology Fall 2000 Seminar Series 

Mondays at 11 AM in Room 1111 Veterinary Teaching Hospital (unless otherwise noted) 

Aug. 25 

Sept. 5 

Yue Zou (University of Texas Medical Branch) - “DNA Damage Recognition in 

Nucleotide Excision Repair” 

VTPP Faculty Candidate 

Tom Weber (Pacifi c Northwest National Laboratory, Battelle, Inc.) – “Prostanoid 

Receptor Alternative Splice Variance” 

Tues 4 PM 

108 BCBP Co-Sponsored by Human Nutrition 

Sept. 12 

Tues 4 PM 

Sept. 18 

Sept. 25 

Oct. 2 

Oct. 6 

Fri 12 PM 

Oct. 10 

Tues 12 PM 

Oct. 16 

Gadiparthi Rao (University of Texas Medical Branch) – “Oxidants and Growth 

Regulatory Mechanisms in Vascular Smooth Muscle Cells” 


No Seminar 

Matthew Reed (Lovelace Respiratory Research Institute) – “Selection of 

Health Assays for an Air Pollution Toxicology Program: The National 

Environmental Respiratory Center as a Case Study” 

Cynthia Warrick (Howard Univ. School of Pharmacy) – title to be announced 

SRPH Faculty Candidate 

Ron Tjalkens (University of Michigan) – “Differential Cellular Regulation of 

the Mitochondrial Permeability Transition (MPT) in 1,3-Dinitrobenzene- 

Induced Encephalopathy” 


Bhakta Ranjan (National Institutes of Health) – “Insulin-like Growth Factor-I 

Receptor Signaling” 


To be announced 

Oct. 23 No Seminar **GCSOT Oct. 26-27** 

Oct. 30 

Nov. 9 

Thurs 4 PM 

Nov. 13 

Nov. 20 

Nov. 29 

Mace Barron (Independent Consultant) - title to be announced 

SRPH Faculty Candidate 

Gary Krishnan (Eli Lilly & Company) – “Hedgehog Signaling from the Brain 

to the Bone” 

Alex Simonian (TAMU, Biochemistry & Biophysics) – “Biosensors: From a 

Simple Idea to Great Perspectives” 

Paul Meltzer (National Human Genome Research Institute, NIH) – “Use of 

cDNA Microarrays for Functional Analysis of Human Cancer” 

Dorr Dearborne (Case Western Reserve University) – “Microbiology and 

Indoor Air Quality” 

Wed 4 PM 

110 Koldus Co-Sponsored by Plant Pathology 

Dec. 4 

Patricia Tithof (University of Tennessee) – “Components of Cigarette Smoke 

Induce Endothelial Cell Apoptosis: Role of Phospholipase A2-Mediated 

Release of Arachidonic Acid” 

For more information call the Toxicology Office at 845-5529

Faculty of Toxicology Spring 2000 Seminar Series 

Monday at 11:00 a.m.; Veterinary Small Animal Clinic, Room 1111 

Jan. 21 Doyle Graham, M.D., Ph.D. “Molecular Pathogenesis of Hexane and 

*Friday* Vanderbilt University Medical Center Carbon Disulfi de Neurotoxicity” 

Pathology 


Jan. 24 Herman Saatkamp, Ph.D. ”The Hidden Structure of Science and 

Indiana Univ.-Purdue Univ. Indianapolis Medicine: Ethics” 

Liberal Arts 

Hosts: Larry Johnson and Jim Wild 

Jan. 27 Bert O’Malley, M.D. “Coactivators: Power Boosters for 

*Thursday* Baylor College of Medicine Steroid Receptors” 

Molecular & Cellular Biology 

Hosts: Fuller Bazer and Steve Safe 

Feb. 8 Elizabeth George, Ph.D. “Genotoxicity of Munitions Compounds 

*Tuesday* US Environmental Protection Agency and Metabolites: In vitro and In vivo” 

NHEERL-Environmental Carcinogenesis 


Feb. 14 

Feb. 21 

No Seminar 

No Seminar 

Feb. 28 Hilary Godwin, Ph.D. “Why is Lead Toxic? Unraveling the 

Northwestern University 

Molecular Mechanism(s) of Lead 

Chemistry 

Poisoning” 

Host: Evelyn Tiffany-Castiglioni 

Mar. 6 David Via, Ph.D. “Macrophage Scavenger Receptors: A 

Baylor College of Medicine 

Role in Atherosclerosis and Stroke” 

Medicine 

Host: Ken Ramos 

Mar. 13 No Seminar 

Mar. 20 

No Seminar 

Mar. 29 Rossanne Philen, M.D. “Career & Internship Opportunities in the 

*Wednesday* Centers for Disease Control CDC and US Public Health Service” and 

3:00 PM Natl Center for Environmental Health “Toxic Oil Syndrome in Spain - 

Host: Betty Dabney 

A Continuing Mystery” 

Apr. 3 Charlene McQueen, Ph.D. “Susceptibility to Aromatic Amine 

University of Arizona 

Genotoxicity: Do the N-Acetyltransferase 

Pharmacology & Toxicology 

Polymorphisms Play a Role?” 


Apr. 11 Scott Senseman, Ph.D. “Using Solid Phase Extraction Disks as 

*Tuesday* Texas A&M University Storage Devices for Pesticides” 

Soil & Crop Sciences 

Hosts: Shawna Lemke & Kim Miller 

Apr. 19 Mr. Mike James “Career and Internship Opportunities in 

*Wednesday* James Environmental, Inc. Environmental Consulting” and 

3:00 PM Host: Betty Dabney “Case Study: Bhopal, India - Union 

Carbide’s Methyl Isocyanate Tragedy” 

Apr. 24 Miguel Mora, Ph.D. “Wildlife Contaminant Issues of the 

Texas A&M University 

U.S.-Mexico Border” 

Wildlife and Fishery Sciences 


May 1 Geoffrey Kapler, Ph.D. “Complex Regulation of Replication 


Origin Firing in a “Simple” Eukaryotic 

Medical Biochemistry & Genetics Model System” 



Faculty of Toxicology Fall 1999 Seminar Series 


Sept. 13 K.C. Donnelly, Ph.D. “A Toxicological Tour of Azerbaijan” 


Veterinary Anatomy & Public Health 


Sept. 21 Yvon Delville, Ph.D. ”Development and the Neurotoxicity of 

*Tuesday* University of Texas – Austin Aggression in Golden Hamsters” 

Psychology 


Sept. 27 Karen Snowden, Ph.D “Environmental Detection of Protozoan 


Parasites in Water” 

Veterinary Pathobiology 


Oct. 4 

No Seminar 

Oct. 11 Tzung-Fu Hsieh, Ph.D. “Development of Microarray Technology 


for the Study of Arabidopsis 

Biology 

Embryogenesis” 


Oct. 18 Dale Christensen, Ph.D. “ Molecular Braille, a Novel Technology 

Novalon Pharmaceutical Corporation for Evaluation of Nuclear Receptor 

Assay Development 

Function” 

Host: Marc Holderman 

Oct. 25 Alvaro Puga, Ph.D. “Role of the Ah Receptor in Cell Cycle 

University of Cincinnati 

Regulation: Biological Consequences 

Environmental Health 

of the Interaction Between the AhR 


and the Retinoblastoma Protein” 

Nov. 1 Claudia S. Miller, M.D., M.S. “Are We on the Threshold of a New 

Univ. of Texas Health Science Center (Environmental) Theory of Disease? 

South Texas Environmental 

From Sick Building Syndrome to the 

Education and Research 

Gulf War” 


Nov. 8 Kip Panter, Ph.D. “Impact of Poisonous Plants on 

U.S. Department of Agriculture Reproduction in Livestock” 

Poisonous Plants Research Laboratory 

Host: Charles Ake 

Nov. 15 Barry Astroff, Ph.D. “Industrial Strength Toxicology” 

Bayer Corporation 



Nov. 22 Monica Valentovic, Ph.D. “Halonaniline Nephrotoxicity” 

Marshall University School of Medicine 

Pharmacology 


Nov. 29 

No Seminar 

Dec. 6 Fang Liu, Ph.D. “SMADs and TGF-β Signaling” 

Rutgers University 

Center for Advanced Biotechnology 

& Medicine 


Faculty of Toxicology Spring 1999 Seminar Series 


Feb. 8 Joseph M. Betz, Ph.D. “Quality and Safety of Botanical Dietary 

U.S. Food & Drug Administration 

Supplements” 

Cntr. for Food Safety & Applied Nutrition 

Host: Tam Garland 

Feb. 15 Robert Burghardt, Ph.D. “A Look at Benzo[a]pyrene on the 


Micrometer Scale” 



Feb. 22 Thomas Klabunde, Ph.D. “Structure-Based Design of Analogues 


of Anti-Infl ammatories as Drugs Against 


Transthyretin- Associated Amyloid 


Diseases” 

Mar. 1 Teri Rowles, Ph.D. “Toxicology in Protected Marine 

National Marine Fisheries Service Species: A Management Perspective” 

Offi ce of Protected Resources 


Mar. 8 Yoichi Osawa, Ph.D. “Hemoproteins as Targets of Reactive 

University of Michigan 

Metabolites: Toxicological Implications” 

Pharmacology 


Mar. 15 

No Seminar: Society of Toxicology Annual Meeting, New Orleans, LA 

Mar. 22 Hagan Bayley, Ph.D. “Engineered Protein Pores as 


Biosensors” 

Medical Biochemistry & Genetics 


Mar. 29 Lowell Sever, Ph.D. “Occupational and Environmental 

Univ. of Texas Health Science Center Agents and the Etiology of Neural 

School of Public Health 

Tube Defects: What is the Evidence?” 


Apr. 5 Anil Jaiswal, Ph.D. “Antioxidant Regulation of Genes 


Encoding Enzymes that Detoxify 

Pharmacology 

Xenobiotics and Carcinogens” 


Apr. 12 Jack Nation, Ph.D. “Heavy Metal Exposure and 

*11:15 am* Texas A&M University Psychoactive Drugs: Interactions” 

Psychology 


Apr. 19 David Carlson, Ph.D. “Craniofacial Anomalies in the Lower 

Baylor College of Dentistry 

Rio Grande Valley: An Overview of the 

Cntr. for Craniofacial Research & Diagnosis BCD-TAMUS Comprehensive Oral 

Host: Fuller Bazer 

Health Center of Discovery” 

Apr. 26 Amy Ridall, Ph.D. “Osteopontin Regulation: A Model for 

Univ. of Texas Health Science Center Interacting Transcription Factors That 

Dental Branch 

Regulate Bone Remodeling” 


May 3 Claudia S. Miller, M.D., M.S. “Are We on the Threshold of a New 

Univ. of Texas Health Science Center (Environmental) Theory of Disease? 

South Texas Environmental 

From Sick Building Syndrome to 

Education and Research 

Gulf War Syndrome” 



Faculty of Toxicology Fall 1998 Seminar Series 

Mondays at 11:00 a.m.; Veterinary Small Animal Clinic, Room 1111 

For more information call the Toxicology Office at 845-5529. 

Sept. 14 Janee' van Waes, D.V.M., Ph.D. "Molecular Mechanisms of Phenytoin- 


Induced Craniofacial Malformation" 



Sept. 21 Naisyin Wang, Ph.D. "Statistical Tools Useful to Toxicologists" 


Statistics 


Sept. 28 David Dix, Ph.D. "Expression and Function of HSP 70s 

U.S. Environmental Protection Agency 

During Spermatogenesis and 

Reproductive Toxicology Division 

Embryogenesis" 

Host: Dr. Rick Finnell 

Oct. 5 George Daston, Ph.D. "Maternal Toxicity, Zinc and Abnormal 

Proctor & Gamble Company 

Development" 

Miami Valley Laboratories 

Host: Dr. Rick Finnell 

Oct. 12 Rajesh Miranda, Ph.D. "Hormonal Growth Factor Regulation 


of Cell Fate in the Developing Cerebral 

Medical Anatomy 

Cortex" 


Oct. 19 Doug Park, Ph.D. "Modification of the Mutagenic Potential 

Louisiana State University 

of Aflatoxin by Fumonisin and Intrinsic 

Food Science 

Components of Corn" 


Oct. 26 Michael Kladde', Ph.D. To be announced 




Nov. 2 

*No Seminar* 

Nov. 9 Michael MacLeod, Ph.D. "Transcription Factor Hijacking and 

U.T. M.D. Anderson Cancer Center 

Disruption of Gene Expression by 

Carcinogenesis 

DNA Damage" 

Nov. 16 


*No Seminar* 

Nov. 23 Mary Trucksess, Ph.D. "Research Opportunities for 

U.S. Food & Drug Administration 

Toxicologists at FDA" 

Center for Food Safety & Applied Nutrition 


Wed. Martin Philbert, Ph.D. "Nano-OptoChemical Systems: The 

Dec. 2 University of Michigan Problem of Small Volumes and 

Environmental Industrial Health 

Physiologic Change in CNS 


(Size Does Count)" 

Dec. 7 Andrew Butler, Ph.D. "Transcription Regulation of Ornithine 

U.T. M.D. Anderson Cancer Center 

Decarboxylase" 



Dec. 14 Lynn Zechiedrich, Ph.D. "Potential New Protein-DNA Adduct 


Repair Systems in E. coli" 

Microbiology & Immunology 


Appendix F 

Annual Report of the IFT 

(January 1, 2005 - April 30, 2006)

Annual Report 

of the 

Interdisciplinary Faculty of Toxicology 

January 1, 2005 – April 30, 2006 

Prepared by 

Kim Daniel, Program Assistant 

Robert C. Burghardt, Chair

IFT Annual Report 

June 2006 

I. Mission and Unique Contributions 

The major function of the Interdisciplinary Faculty of Toxicology (IFT) is the administration of 

graduate programs leading to the Master of Science and Doctor of Philosophy degrees in Toxicology, in 

conformance with the rules of the Office of Graduate Studies of Texas A&M University. The IFT provides 

leadership for activities and functions which are critical for the development and growth of a research and 

training program that is nationally recognized in this important area of the biomedical sciences 

collectively referred to as Environmental Health Sciences. 

Toxicology research and training at Texas A&M University was initiated in 1970 and was extensively 

reorganized in the late 1980s to reflect the interdisciplinary nature of the environmental health research 

and training activities on this campus. In 1989, faculty from six Colleges and seventeen Departments 

within the University and other affiliated State and Federal Laboratories formed the Interdisciplinary 

Faculty of Toxicology (IFT). The new IFT represented a unique model for developing a graduate 

program that encompasses students and faculty from different administrative units. Students receive 

their Toxicology degree which is administered by the IFT; however, all students are members of the 

Department of their mentors, and these Departments receive graduate credits for Toxicology students. In 

addition, all students must fulfill the academic requirements of their home Departments and the IFT. This 

approach facilitates the recruitment of students into the IFT from multiple Departments and Colleges and 

greatly facilitates the development of trainees who not only have a basic understanding of the 

environmental health sciences but also appreciate the skill sets of scientists with different research 

interests. Currently, the IFT involves 52 faculty from 15 Departments and 6 Colleges at Texas A&M 

University as well as several faculty from units of the Texas A&M Health Science Center (TAMHSC), 

including the College of Medicine, Institute of Biosciences and Technology (IBT), and the School of Rural 

Public Health. Although Texas A&M University and the TAMHSC are completely self-governing 

components of the Texas A&M System, the structure of the IFT accommodates students from both 

Institutions. The IFT Executive Committee consists of 7 members of the IFT and one Graduate Student 

member, and provides administrative oversight for the activities of the IFT. A complete list of the IFT 

faculty and their Departmental, College and School affiliations is given in Appendix A. 

The IFT, through exceptional leadership of Dr. Stephen H. Safe and several other key faculty, along 

with the research and training activities of IFT members, has established an internationally recognized 

program incorporating Environmental Health Research, Training, and Outreach at Texas A&M University. 

Development of the IFT model for interdisciplinary training in Toxicology was critical for unifying diverse 

campus programs in this discipline and was important for our first successful NIEHS Toxicology Training 

Grant application (funded 1992) which has been renewed twice and is now in its 14 th year of continuous 

funding. The NIEHS Training Grant in Toxicology serves as a model for many other life sciences 

initiatives at Texas A&M University. The IFT benefits from new and expanding initiatives in the 

environmental health sciences that provide a stimulating and challenging atmosphere for graduate 

students, postdoctoral trainees and faculty. The Superfund Basic Research Program (SBRP) Project at 

Texas A&M University was originally funded in 1989 and has been renewed twice, and is now in its 17 th 

year of continuous funding for this highly interdisciplinary research project. A concept for a Center for 

Environmental and Rural Health (CERH) was developed by IFT faculty from several disciplines and, in 

1998, a new NIEHS Environmental Health Science Center of Excellence was awarded to Texas A&M 

University. The CERH, whose membership involves over half of the IFT, was successfully renewed in 

2002 and in now in its 8 th year of continuous funding. NIEHS has also funded the Partnership for 

Environmental Education and Rural Health (PEER) which focuses on integrating environmental health 

science into grades 6 through 8 in rural schools in Texas. This program provides unique opportunities for 

graduate student participation. Collectively, the IFT is responsible for numerous unique contributions, 

many of which result from the convergence of the NIEHS-funded programs including the Toxicology 

Training Grant, CERH, SBRP, and PEER program (Figure 1) which also sponsor additional local and 

regional symposia and conferences. These unique programs have greatly: 1) increased the scope of 

1


June 2006 

environmental health sciences research 

and faculty interactions at the University; 

2) enhanced the quality and diversity of 

the research environment for our trainees; 

and 3) increased the visibility and 

prominence of Texas A&M University as a 

leader in environmental health research 

and training. These are supplemented by 

an established campus-wide Toxicology 

Seminar series which brings in 

toxicologists as well as collaborators from 

other Superfund Program Projects and 

Centers of Excellence, and also by 

regional Gulf Coast Society of Toxicology 

meetings. Both of these forums provide 

personal and professional development 

opportunities for graduate and 

postdoctoral trainees. 

ENVIRONMENTAL HEALTH RESEARCH AND 

TRAINING AT TEXAS A&M UNIVERSITY 

peer.tamu.edu 

Figure 1. The IFT is central to multiple environmental health 

science research and training programs at Texas A&M 

University. 

II. Accomplishments 

A. Education 

1. Courses/Instructional changes. The IFT does not administer courses, but rather the faculty 

teach courses in many different departments at the undergraduate, graduate and professional 

levels in both Texas A&M University and in the Texas A&M Health Science Center (see 

Appendix B2). IFT members are responsible for instruction in all of the Core Courses that are 

recommended for all toxicology students (see Appendix B1 for Core Courses). 

2. Undergraduate and graduate degrees in Toxicology. Since January 2005, the IFT has 

awarded eight Doctor of Philosophy and two Master of Science degrees. The IFT does not have 

an undergraduate component. 

May, 2005 

August, 2005 

December, 2005 

May 2006 

Maya Scott, PhD 

Xiangrong Li, PhD 

Wonsuk Yang, PhD 

Sairam Bellum, PhD 

Bhagirathi Dash, PhD 

Xuhong Liu, PhD 

Charlie Partridge, PhD 

Megan Sitzlar, MS 

Qiulin Tan, MS 

Annika Gillespie, PhD 

3. Student recruiting 

The IFT recruits prospective students throughout the year through staff and faculty 

attendance at regional and national meetings, visits to other institutions and by sending materials 

in response to individuals who express interest through our website or e-mail. The reputation of 

many faculty members results in personal contact by prospective students, and those faculty are 

responsible for direct recruitment of those students. Both the IFT website 

(http://toxicology.tamu.edu) and informational brochure have been positive recruiting tools 

(Appendix I). 

2


June 2006 

4. Enrollment (Appendix A) 

A total of 31 graduate trainees are currently majoring in toxicology, and over 20 postdoctoral 

research associates involved in the Toxicology Program. Six students have enrolled in the 

program and ten have graduated since January 2005. 

5. Diversity 

Diversification of the graduate student population is a major goal of the IFT and an objective 

of the Toxicology Training Grant. There are several minority recruitment strategies coupled with 

a strong University policy which supports these efforts for attracting underrepresented groups as 

faculty and students. 

Mrs. Kim Daniel, the IFT Program Assistant, is a member of the Society of Toxicology’s (SOT) 

Committee on Diversity Initiatives. This group organizes the Undergraduate Education Program 

each year at the national SOT meeting, which recruits predominantly minority undergraduate 

students in the sciences and presents an overview of the field of toxicology to them. Mrs. Daniel 

is able to interact directly with the undergraduate participants and the graduate student peer 

mentors about graduate and postdoctoral opportunities at TAMU. In addition to this program, she 

also participates in some recruiting fairs at other Texas undergraduate institutions. 

Drs. Philip Mirkes and Weston Porter have recruited undergraduate students from the 

University of Puerto Rico at Cayey as part of an NIH Research Initiative for Student Enhancement 

(RISE) grant, which provides travel funds for students to gain knowledge and experience at 

graduate institutions in the US. Two students participated in a summer-long research experience 

in their laboratories. The CERH is also engaged in this activity and has identified three students 

who will each work in the laboratories of Drs. Dees, Donnelly, and Porter in the summer of 2006. 

These students are responsible for presenting their research as part of the annual IFT student 

research forum which is held at the end of the summer semester. 

Dr. Robert Burghardt, as a component of CERH outreach activities in conjunction with the 

IFT, has developed microscopy and image analysis workshops targeted to advanced 

undergraduate and beginning graduate students from minority institutions affiliated with the Texas 

A&M University System including Prairie View A&M University and Texas A&M University, 

Kingsville. These workshops are designed to provide microscopy training and expose students to 

toxicology research and methods supported by the CERH. He has developed extensive 

collaborations with Dr. Gary Newton at Prairie View A&M University which have resulted in 

standardization of technical methods and scientific equipment as well as student exchanges 

among Dr. Newton’s laboratory at Prairie View and those of several members of the CERH 

Developmental Biology Research Core at Texas A&M. 

6. Industrial partnerships 

There are no industrial partnerships that have arisen from educational activities of IFT 

members. However, several partnerships have developed as the result of research activities on 

individual members of the IFT. These are listed in Section B.5. 

7. Student placement (Appendix C) 

Ten Toxicology degrees have been awarded since January 2005, eight Ph.D. and two M.S. 

Of those, five are employed as postdoctoral research associates, two are research scientists, one 

is a clinical assistant professor, one is an environmental consultant, and one is an industry 

toxicologist. Many IFT faculty also mentor students majoring in other areas, and during the same 

period of time, nineteen additional degrees were awarded to those students: fifteen Ph.D., two 

M.P.H., and two M.S. degrees. 

B. Research 

1. Publications (Appendix D) 

A total of 206 peer-reviewed manuscripts and 10 book chapters have been published by IFT 

faculty since January 2005. Of the peer-reviewed journal articles, 19.5% have been 

3


June 2006 

collaborative efforts between two or more faculty members, and graduate trainees have been 

first author on 19.9% of these papers. 

2. Grants (Appendix E) 

The IFT faculty have at least 107 active grants (sources: 54 from NIH, 15 from USDA, 4 from 

NSF and 34 from other agencies) totaling in excess of $15 million dollars annual direct cost. 

Collaboration among faculty members on grants is 35% for NIH, 47% for USDA, and 26% 

overall. 

3. Awards (Appendix F) 

The faculty were recognized many times in 2005 and 2006 for their research and scholarly 

activities at the local, state, national and international levels. Dr. Tim Phillips received both 

the esteemed Association of Former Students’ Distinguished Achievement Award in 

Research and the Bush Award for Excellence in International Research during this period. 

4. Presentations (Appendix G) 

The faculty presented research at over 25 local, 130 national and 63 international venues. 

5. Other (IP, etc.) 

A. Patents. Five IFT faculty have patents awarded or pending. They are Dr. Robert S. 

Chapkin (one awarded, one provisional), Dr. Timothy D. Phillips (two awarded), Dr. 

Suresh D. Pillai (one pending), Dr. Stephen H. Safe (one awarded, one pending) and Dr. 

James R. Wild (two awarded). 

B. Industrial Partnerships. Dr. Timothy Phillips developed a patented modified clay material 

(tradename NovaSil) which has been shown efficacious in sorbing aflatoxin and reducing 

the toxic side effects in animal models. A new Texas A&M University-based company, 

Texas Enterosorbents, Inc., was launched from the Texas Commercialization Center in 

2005 based on Dr. Phillips’ NovaSil research. Dr. Stephen Safe has developed and 

patented new potential anti-cancer compounds that are derivatives of diindolylmethane 

(DIM), a metabolite formed from the phytochemical, indole-3-carbinol, which is widely 

found in cruciferous vegetables. One class of these compounds targets peroxisome 

proliferators-activated receptor (PPAR), while another class targets orphan receptors 

including nerve growth factor-induced-B [NGFI-B (Nur77)]. A new biopharmaceutical 

company has recently entered into an exclusive license agreement with the Texas A&M 

University System for patents and intellectual property related to substituted DIM analogs. 

Plantacor's multiple therapeutic product candidates, licensed from the Texas A&M 

University System and the MD Anderson Cancer Center, are currently in various stages of 

pre-clinical development. Drs. Robert Chapkin, Joanne Lupton, Laurie Davidson, and 

Nancy Turner have developed and patented noninvasive technology to monitor changes 

in colon gene expression profiles over time as a function of diet, chemical carcinogen 

and/or radiation exposure. This patented methodology recovers colon cell mRNA from 

fecal material and in combination with microarray technology is used to detect changes in 

global colon gene expression profiles. The feasibility of this technology has been tested in 

humans and a rat experimental colon carcinogenesis model. Specific markers have been 

identified, levels of which are diagnostic for dietary effects on colonic tumors. In order to 

accelerate the translation of this research to the clinic, Drs. Chapkin, Lupton, and 

Davidson are in the process of establishing a private company, Cologenomics, Inc. 

C. Service (Appendix H) 

1. Departmental, college and university service. IFT faculty serve at all levels within the 

University, the System and also the Health Science Center. 

4


June 2006 

2. National and international organizations. The faculty are involved in numerous state, national 

and international organizations which promote scholarly activities. 

3. Editorial work. The faculty have provided ad hoc reviews for over 80 peer-reviewed journals. 

There are 33 faculty who serve as Editorial Board members, and 17 who are Editors, Co- 

Editors or Associate Editors. A large number of faculty also serve on extramural grant review 

panels. 

III. Budget 

A. Allocated 

The IFT has received a total of $90,000 for operating expenses, and $40,000 for fellowships 

at the time of this report. Allocations were received from the Vice President for Research 

($60,000), the Office of Graduate Studies ($40,000, designated for Regents’ Fellowships), the 

College of Veterinary Medicine and Biomedical Sciences ($20,000), the College of Agriculture 

and Life Sciences ($5,000) and the College of Science ($5,000). Additional allocations are 

anticipated from the Texas A&M Health Science Center and the Institute of Biosciences and 

Technology ($5,000 each). 

B. Spent 

As of June 1, the IFT has spent or encumbered $80,970 of the operating expense budget, 

and $26,667 of the fellowship budget. The funds have been used to support graduate training in 

the form of the Toxicology Seminar Series, Travel Awards to national and regional meetings and 

supplemental support for students. Additional funds have been used toward office operating 

expenses and staff salaries. 

Toxicology Seminar Series - $11,120. The Toxicology Seminar Series has been held each 

fall and spring semester since 1983. Many faculty and also postdoctoral and graduate trainees 

recruit speakers for the series. The comprehensive schedules for the Spring 2005, Fall 2005 and 

Spring 2006 semesters are provided in Appendix I. For the 2005-2006 academic year, the IFT 

hosted 22 speakers (4 local, 6 state, and 12 national). Travel expenses were provided for each 

speaker, and honoraria were paid to the national and eligible Texas speakers. The graduate and 

postdoctoral trainees are encouraged to interact with the speakers, and regularly do so through 

research discussions and by dining with them. 

Travel Awards and Support - $16,250. The IFT strongly supports trainee attendance and 

participation at national and regional meetings. All students were offered $750 in travel support 

to attend a national meeting, and the IFT fully sponsored the travel for all students who attended 

regional meetings. A total of 18 students attended national meetings (Society of Toxicology, 

Society of Environmental Toxicology and Chemistry, American Association for Cancer Research 

and Keystone Conferences), while 12 attended the Gulf Coast Chapter-Society of Toxicology 

meeting. Additional support will be provided for students attending the Teratology Society and 

Endocrine Society meetings this summer. 

Supplemental Support - $4984. Funds have been provided to Regents’ Fellows in the form of 

health insurance premiums and tuition supplementation. 

Other - $48,615. These funds were used to support the IFT administrative office (telephone, 

computer and software, supplies and small equipment) and staff salaries. The staff include a 

Program Assistant (100% effort), a Business Coordinator (15% effort) and a student worker. 

5


June 2006 

IV. Future Plans 

A. Directions (strategic plan and goals for IDP, federal initiatives, etc.) 

The next external review of the IFT is scheduled for May, 2007. In the last IFT external 

review, which was conducted in 1998, the panel of distinguished toxicologists comprising the 

External Review Committee concluded: "Overall, the External Review Committee considers the 

IFT to be an outstanding program, which has a justly deserved international reputation of 

excellence." Our immediate goal is therefore to continue building on this “international reputation 

of excellence” by sustaining active programs in Toxicology and in the broader area of 

environmental health sciences that are currently supported by the NIEHS. The IFT will therefore 

capitalize on new and expanding initiatives in the environmental health sciences that will provide 

a stimulating and challenging atmosphere for graduate students, postdoctoral trainees and 

faculty. 

To this end, the second 5 year renewal proposal of the Texas A&M University Center for 

Environmental and Rural Health (for the period 04-01-2007 to 01-31-2011, years 10-14) was 

recently submitted by the Center Director, Dr. Philip Mirkes. Over half of the IFT is involved in 

this Center of Excellence and several new initiatives have been identified that will significantly 

impact the IFT over the next 5 years. This includes the establishment of a functional Integrated 

Health Sciences Facility Core with the mission of increasing translational research in 

environmental health sciences. This will require the recruitment of new IFT members from the 

Texas A&M University System Health Sciences Center as well as the recruiting of new clinical 

investigators with interest in nutrition/environmental health as well as birth defects. Other 

initiatives include the expansion of shared facility cores and development of new resources in the 

emerging area of metabolomics, and to provide leadership and utilization in the use of resources 

available through the Texas Institute for Genomic Medicine (TIGM). Longer term goals include 

sustaining the Center’s leadership in basic and clinical aspects of environmental health research 

and further enhancement of new basic research findings in an effort to improve global human 

health, particularly as it relates to underserved and rural populations. 

In addition, the third 5 year renewal of the Toxicology Training Grant was submitted in May, 

2006 requesting support for 9 trainees (6 graduate students and 3 postdoctoral fellows) for each 

year (for the period 07-01-2007 to 06-30-2012, years 16-20) by the Training Grant Director, Dr. 

Stephen H. Safe. Our goal is to utilize this funding to expand IFT member training of the next 

generation of environmental health scientists. 

The Superfund Basic Research Program (SBRP) Project at Texas A&M University was last 

renewed from 2005-2008, and represents over 18 years of continuous funding for this highly 

interdisciplinary research project that also involves numerous toxicology graduate students. 

Strategic planning is already underway for the preparation of a competing renewal of this program 

project grant (for the period 04-01-08 to 03-31-2012) under the direction of Drs. Stephen H. Safe 

and K.C. Donnelly. 

Additional opportunities for outreach activities focused on integrating environmental health 

science education into grades 6 through 8 in rural schools in Texas is ongoing under the 

leadership of Dr. Larry Johnson. 

In addition to these core programs that have provided great visibility and prominence of Texas 

A&M University as a leader in environmental health research and training, new interdisciplinary 

initiatives are being developed that focus on new program projects in toxicogenomics, the role of 

environmental factors in birth defects, and the role of environmental factors including nutrition on 

colon cancer. Members of the IFT including members of the CERH and SBRP will continue to 

provide leadership in securing state-of-the-art analytical tools for shared use through competitive 

national shared instrumentation grant programs supported by the National Institutes of Health and 

6


June 2006 

National Science Foundation. The IFT is also committed to increasing diversity and is currently 

exploring the development of a Bridges to the Doctorate R25 training grant proposal to utilize 

components of the Texas A&M University System minority serving institutions to strengthen the 

multidisciplinary and institutional linkages needed to facilitate minority student matriculation into 

Ph.D. programs in environmental health sciences under the direction of members of the IFT. 

B. Budget 

The IFT respectfully requests $163,500 in funds to support FY07 activities. 

$12,000 Toxicology Seminar Series 

$18,000 Travel Support for Trainees 

$54,000 Graduate Student Fellowships (2 fellowships @ $27,000 which includes 

$20,000 stipend, tuition and fees, and health insurance) 

$50,000 Administrative support (salaries and office expenses) 

$ 2,500 Recruitment of underrepresented groups (described in detail below) 

$27,000 New trainee support (described in detail below) 

C. Special Items 

1. Supplemental support for minority recruiting. Recruitment of underrepresented groups is a 

goal of the Toxicology Training Grant and the IFT, and is spelled out in a strong University 

policy which supports these efforts. The IFT requests recurring funding of $2,500 earmarked 

exclusively for recruitment of minority students. Justification of this request is based upon 

annual evaluation of application packets for prospective toxicology students. There are often 

minority students who apply whose record shows potential but may be below the 

qualifications of other applicants. We seek to use this funding to invite potential minority 

students for interviews and interactions with IFT faculty in an effort to increase the number of 

underrepresented minority students in the Toxicology Program. 

2. One semester support for entering/rotating graduate students. New funds are requested to 

support entering IFT graduate students for the period of one semester in order to provide 

laboratory rotations to uncommitted students. The IFT request recurring funding for 4 

students, one semester for a total of $27,000 (i.e., $6,750 per student for 4 months each). 

The justification for this request is that to ensure the proper match between trainee and 

mentors, rotations in laboratories provide the opportunity for both parties to understand 

research interests and goals and compatibility. Many mentors would rather not consider 

students when stipends must be provided to students who have no commitment to a 

laboratory. This mechanism would enhance the placement and optimal match between 

students and mentors. 

3. Restoration of relationships with departments. An important need of the IFT is the 

restoration of the previous relationships with Departments. When the Interdisciplinary 

Faculties received independent status, relationships with home departments were significantly 

changed which resulted in the disincentive to support IFT activities because departments 

were no longer receiving credit for students enrolled in interdisciplinary programs. In one 

college IFT students were no longer considered eligible for graduate student awards 

administered by the college. We request that the mechanism to give individual departments 

credit for the IFT students be developed. In addition, graduate student tuition relief provided 

by President Gates to departments was not used for IFT students, resulting in an increasing 

financial burden for their mentors. 

7

List of Appendices 

Appendix A Faculty and Trainees 

Appendix B Curriculum and Courses Taught 

Appendix C Student Placement 

Appendix D Publications 

Appendix E Grant Support 

Appendix F Faculty Awards 

Appendix G Presentations 

Appendix H Service Activities 

Appendix I 

Appendix J 

Seminar Schedule 

Recruiting Brochure 

Appendix K Faculty Curriculum Vitae 

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June 2006 

APPENDIX A: Faculty & Graduate Trainees 

Faculty 

Name Dept. College System Part 

Abbott, Louise C. VIBS CVM TAMU 

Autenrieth, Robin l. CVEN Engineering TAMU 

Ball, Judith M. VTPB CVM TAMU 

Barr, A. Catherine TVMDL CVM TAMU 

Bernstein, Lori R. MCM Medicine TAMHSC 

Bickham, John W. WFSC COALS TAMU 

Bratton, Gerald R. VIBS CVM TAMU 

Burghardt, Robert C. * VIBS CVM TAMU 

Busbee, David L. VIBS CVM TAMU 

Calvin, James A. AVPR/STAT Admin. / Science TAMU 

Carroll, Raymond J. STAT Science TAMU 

Chapkin, Robert S. ANSC COALS TAMU 

Dees, W. Les VIBS CVM TAMU 

Donnelly, K.C. EOHS SRPH TAMHSC 

Fackler, John P. CHEM Science TAMU 

Finnell, Richard H. IBT / VIBS IBT / CVM TAMHSC / TAMU 

Harvey, Roger B. USDA/VIBS CVM TAMU 

Johnson, Larry VIBS CVM TAMU 

Kier, Ann B. VTPB CVM TAMU 

Ko, Gladys Y.L. VIBS CVM TAMU 

Kubena, Leon F. USDA COALS TAMU 

Miranda, Rajesh C. NEXT Medicine TAMHSC 

Mirkes, Philip E. *** VTPP CVM TAMU 

Mora, Miguel WFSC COALS TAMU 

Parrish, Alan R. SBTM Medicine TAMHSC 

Phillips, Timothy D. ** VIBS CVM TAMU 

Pietrantonio, Patricia V. ENTO COALS TAMU 

Pillai, Suresh POSC COALS TAMU 

Porter, Weston W. *** VIBS CVM TAMU 

Ramaiah, Shashi K. *** VTPB CVM TAMU 

Raushel, Frank M. CHEM Science TAMU 

Reagor, John C. TVMDL CVM TAMU 

Russell, Leon H. VIBS CVM TAMU 

Safe, Stephen H. *** VTPP/IBT CVM / IBT TAMU / TAMHSC 

Schroeder, Friedhelm VTPP CVM TAMU 

Senseman, Scott A. SCSC COALS TAMU 

Sherman, Michael STAT Science TAMU 

Simanek, Eric CHEM Science TAMU 

Sinden, Richard R. IBT IBT TAMHSC 

Spencer, Thomas E. ANSC COALS TAMU 

Spiegelman, Cliff STAT Science TAMU 

Stallone, John N. VTPP CVM TAMU 

Stoica, Gheorghe VTPB CVM TAMU 

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June 2006 

Thompson, James A. VLAM CVM TAMU 

Tian, Yanan *** VTPP CVM TAMU 

Tiffany-Castiglioni, Evelyn VIBS CVM TAMU 

Turner, Nancy D. ANSC COALS TAMU 

Walker, Cheryl L. VTPP-Adjunct CVM TAMU 

Wang, Naisyin STAT Science TAMU 

Wild, James R. BCBP COALS TAMU 

Wilson, Cody L. EOHS-Adjunct SRPH TAMHSC 

Wilson, Emily SBTM Medicine TAMHSC 

* IFT Chair 

** IFT Vice Chair 

*** Executive Committee Member 

Graduate Trainees 

Name Dept. College Advisor(s) 

Banerjee, Atrayee VTPB CVM Ramaiah 

Chadalapaka, Gayathri VTPP CVM Safe 

Chen, Chien-Cheng VTPP CVM Safe 

Elhamaky, Ahmed VIBS CVM Busbee 

Gu, Xinsheng VTPP CVM Tian 

Gustafson, Tanya VIBS CVM Porter 

Hill, Denise VIBS CVM Finnell/Donnelly 

Hosako, Hiromi VTPP CVM Mirkes 

Jutooru, Indira VTPP CVM Safe 

Kelley, Matthew VIBS CVM Donnelly 

Kern, Rory BICH COALS Wild 

Kwak, Hyeong-IL “Henry” VIBS CVM Porter 

Laban, Geoff VTPP CVM Bickham 

Laffin, Brian VIBS CVM Porter 

Lee, BoYeon VIBS CVM Dees 

Lee, Wan-Ru VTPP CVM Safe 

Lingenfelter, Rebecca VIBS CVM Donnelly 

Mays, Travis VTPP CVM Reagor 

Naspinski, Christine VIBS CVM Donnelly/Autenrieth 

Naufal, Ziad VIBS CVM Donnelly 

Papineni, Sabitha VTPP CVM Safe 

Phillips, Tracie VIBS CVM Donnelly 

Taylor, John VIBS CVM Phillips 

Thuett, Kerry VIBS CVM Abbott/Castiglioni 

Vanderlaag, Kathy VTPP CVM Safe 

Viveros, Leamon BICH COALS Wild 

Wellberg, Elizabeth VIBS CVM Porter 

Xie, Ying VTPP CVM Tian 

York, Melissa VTPP CVM Safe 

Zhang, Shu VTPP CVM Safe 

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June 2006 

APPENDIX B: Courses 

Part 1: IFT Graduate Curriculum 

Admission into the toxicology program requires the successful completion of courses in 

advanced biology and/or chemistry or their equivalents. The completion of a 

Thesis/Dissertation is required for both the M.S. and Ph.D. degrees in toxicology. 

CORE COURSES 

It is strongly recommended that all students in the Ph.D. program complete the core 

courses listed below or their equivalents. Degree plans for individual students vary 

depending on the student's background and research focus. Doctoral students normally 

complete 36 hours of coursework and 60 hours of research credit. The toxicology 

program emphasizes research as most students are placed in laboratories during their 

first semester and continue to conduct research while they complete 2-3 courses per 

semester. 

BICH 603 (taught each Fall semester) 

General Biochemistry I, 3 credits. The biochemical properties of macromolecules 

found in living matter; proteins, enzymes, and nucleic acids. 

STAT 651 (taught each Fall, Spring and Summer semester) 

Statistics in Research I, 3 credits. A non-calculus exposition of the concepts, 

methods and usage of statistical data analysis. T-tests, analysis of variance and 

linear regression. 

VIBS 618 or 619 

Food Toxicology, 3 credits. The study of food additives, chemical and microbial 

contaminants, and naturally occurring toxins associated with foods. 

VIBS 670 (taught Fall semester in odd-numbered years) 

Basic Environmental Toxicology, 3 credits. Introduction to general principles of 

toxicology; tests methods, target organs and risk assessment for engineers and 

other non-toxicologists; risk assessment methodology. 

VMID 686 (taught Spring semester in even-numbered years) 

Scientific Ethics, 1 credit. Overview of ethical issues encountered by toxicologists 

in research, resources, interactions with public, and application of findings. 

VTPP 673 (taught Fall semester in even-numbered years) 

Metabolic & Detoxication Mechanisms, 3 credits. Fate of foreign compounds; their 

inhibitory and antagonistic action toward normal metabolic processes of the animal 

body. 

VTPP 676 (taught Spring semester in even-numbered years) 

Genetic & Molecular Toxicology, 3 credits. Mechanisms of toxicant-induced target 

organ toxicity with emphasis on molecular control of mammalian and cell growth 

differentiation. 

VTPP 681 (taught each Fall and Spring semester) 

Toxicology Seminar, 1 credit. Review and discussion of current scientific work in 

toxicology and related subjects. 

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ELECTIVE COURSES 

Toxicology electives are selected from advanced courses which provide additional 

expertise in specialized areas within the sub-disciplines of cellular and molecular 

toxicology, reproductive and neurotoxicology, and environmental toxicology and food 

safety. 

Electives may be selected from, but are not limited to the following courses: 

BICH 604 General Biochemistry II, 3 credits 

BICH 631 Molecular Genetics, 3 credits (cross listed as GENE 631) 

BICH 654 Structural Biochemistry, 3 credits 

BICH 662 Eukaryotic Transcription, 1 credit 

BIOL 681 Seminar, 1 credit 

CHEM 601 Analytical Chemistry I, 3 credits 

CHEM 602 Analytical Chemistry II, 3 credits 

CVEN 609 Environmental Control of Oil & Hazardous Materials, 3 credits 

CVEN 682 Environmental Remediation of Contaminated Sites, 3 credits 

ENTO 619 Insect Toxicology, 4 credits 

FSTC 606 Microbiology of Foods, 3 credits 

MSCI 610* Pathogenesis of Human Disease, 3 credits 

NUTR 641 Nutritional Biochemistry, 3 credits 

PHEO 600* Principles of Occupational and Environmental Health, 3 credits 

PHEO 611 Occupational Epidemiology, 3 credits 

PHEO 650* Risk Assessment I, 3 credits 

STAT 652 Statistics in Research II, 3 credits 

TAMU 699** Basic Concepts of Tumor Biol. 3 credits 

TAMU 699** Mechanisms of Carcinogenesis, 3 credits 

VIBS 602 Histology, 4 credits 

VIBS 603 Neuroanatomy, 4 credits 

VIBS 605 Chemical Hazard Assessment, 3 credits 

VIBS 607 Applied Epidemiology, 4 credits 

VIBS 614 Biodegradation and Bioremediation, 3 credits 

VIBS 617 Advanced Cell Biology, 1-5 credits 

VIBS 619 Food Toxicology II, 3 credits 

VTMI 649 Immunology, 3 credits 

VTPP 653 Endocrinology, 3 credits 

VTPP 654 Molecular Endocrinology, 3 credits 

VTPP 665 Pharmacology, 4 credits 

WFSC 689 Special Topics in Wildlife Ecotoxicology, 2 credits 

Highly recommended courses shown in bold 

*TAMUS Health Science Center course, requires co-enrollment 

**University of Texas courses, requires special permission to enroll 

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June 2006 

Part 2: Courses Taught by Members of the IFT 

IFT members teach courses throughout TAMU and TAMHSC. 

Course Course Title SCH Instructor 

AGRO650 

Mode of Action and Environmental Fate of 3 S Senseman 

Herbicides 

ANSC 630 Reproductive Biology I 4 TE Spencer 

ANSC 631 Reproductive Biology II 4 TE Spencer 

BIMS 101 Introduction to Biomedical Science 1 LC Abbott 

BIOL 601 Biological Clock 3 GPY Ko 

BIOL/PSYC/VIBS 689 Principles of Neuroscience 3 GPY Ko 

BIOT 603 Applied Principles of Biotechnology 4 SD Pillai 

BIOT 681 Biotechnology Seminar 1 SD Pillai 

CHEM 103 Structure and Bonding 3 JP Fackler 

CHEM 462 Advanced Inorganic Chemistry 3 JP Fackler 

CHEM 672 Bioorganic Reaction Mechanisms 3 FM Raushel 

CHEM 681 Graduate Student Seminar 1 FM Raushel 

ENTO 615 Insect Physiology 3 PV Pietrantonio 

ENTO 619 Insect Toxicology 4 PV Pietrantonio 

FSTC 481 Food Science & Technology Seminar 1 SD Pillai 

FSTC/AGRO/POSC/ Molecular Methods for Microbial 

3 SD Pillai 

VTMI 619 

Characterization 

FSTC/POSC 689 Microbiology of Food Irradiation 3 SD Pillai 

GENE 302 Principles of Genetics 4 JR Wild 

GENE420 Bioethics 3 JR Wild 

GENE420H Honors Studies in Bioethics 3 JR Wild 

MPHY 601 Methods is Cell Physiology 4 E Wilson 

MPHY 604 Advanced Cardiovascular Biology I 4 E Wilson 

NUTR 203 Scientific Principles of Human Nutrition 3 RS Chapkin 

NUTR 481 Seminar 1 ND Turner 

NUTR 642 Nutritional Biochemistry II 3 RS Chapkin 

STAT 636 Methods in Multivariate Analysis 3 C Spiegelman 

STAT 642 Statistical Methods II 3 C Spiegelman 

STAT 643 Biostatistics I 3 N Wang 

STAT 651 Statistics in Research I 3 N Wang 

VIBS 404H Honors Food Toxicology and Safety 3 TD Phillips 

VIBS 432 Public Health Practices 3 KC Donnelly 

VIBS 450 Comparative Mammalian Neurology 3 GPY Ko 

VIBS 612 Mammalian Embryology 4 LC Abbott 

VIBS/PHEO 605 Chemical Hazard Assessment 3 KC Donnelly 

VIBS/PHEO 614 Biodegradation & Bioremediation 3 KC Donnelly 

VIBS 617 Advanced Cell Biology 1 RC Burghardt 

VIBS 617 Advanced Cell Biology 1 WW Porter 

VIBS 618 Food Toxicology 3 TD Phillips 

VIBS 619 Food Toxicology II 3 TD Phillips 

VIBS/PHEO 670 Basic Environmental Toxicology 3 KC Donnelly * 

VIBS 911 Microscopic Anatomy I 4 LC Abbott 

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June 2006 

VIBS 913 Microscopic Anatomy II 4 LC Abbott 

VLCS 931 Bovine Reproduction 1 JA Thompson 

VMID 686 Scientific Ethics 1 L Johnson 

VPAT 681 Clinical pathology seminar 1 SK Ramaiah 

VPAT 681 Histopathology Seminar 1 SK Ramaiah 

VPAT 642 Metabolic Disease 2 SK Ramaiah 

VTMI 601 Fundamentals of Pathobiology 5 JM Ball 

VTMI 647 Virology 4 JM Ball 

VTMI 689 Protein Transport in Mammalian Cells 3 JM Ball 

VTPB 923 Pathology II 3 SK Ramaiah 

VTPP 673 Metabolic & Detoxication Mechanisms 3 SH Safe 

VTPP 676 Genetic and Molecular Toxicology 3 Y Tian 

VTPP 681 Toxicology Seminar 1 SH Safe 

VTPP 910 Veterinary Physiology I 6 JN Stallone 

VTPP 912 Veterinary Physiology II 6 JN Stallone 

Bold type indicates Core Courses for Toxicology graduate students. 

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June 2006 

APPENDIX C: Student Placement (2005-Present) 

Name Degree Current Position 

Sairam Bellum Ph.D. Associate Toxicologist, Lexicon Genetics, Inc., The 

Woodlands, TX 

Bhagirathi Dash Ph.D. Postdoctoral Research Fellow, Dept. of 

Environmental Health Sciences, University of 

California-Berkeley, Oakland, CA 

Xiangrong Li Ph.D. Postdoctoral Research Associate, Dept. of 

Veterinary Physiology & Pharmacology, Texas A&M 


Xuhong Liu Ph.D. Postdoctoral Research Associate, Dept. of 

Neuroscience and Experimental Therapeutics, 

College of Medicine, Texas A&M Health Science 

Center, College Station, TX 

Annika Gillespie Ph.D. Environmental Consultant in the Baltimore, MD and 

Delaware areas 

Charles Partridge Ph.D. Postdoctoral Research Associate, Dept. of 

Biochemistry and Molecular Medicine, University of 

Louisville Health Science Center, Louisville, KY 

Maya Scott, DVM Ph.D. Clinical Assistant Professor, Veterinary Physiology 

& Pharmacology, Texas A&M University, College 

Station, TX 

Megan Sitzlar M.S. Biological Science Technician with a federal agency 

Qiulin Tan M.S. Scientist with a biotechnology company in Dallas, 

TX 

Wonsuk Yang Ph.D. Postdoctoral Research Associate, Dept. of 

Neurology, University of Chicago, Chicago, IL 

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June 2006 

APPENDIX D – Publications 

PEER REVIEWED ARTICLES (Underline - graduate student first author; bold type - IFT faculty) 

Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt R, Liu S, Hill D, Finnell R, 

Wlodarczyk B, Jordan VC and Safe S. 2006. 3-Methylcholanthrene and other aryl 

hydrocarbon receptor agonists directly activate estrogen receptor α. Cancer Res. 66:2459- 

2467. 

Abdelrahim M, Lui S, and Safe S. 2005. Induction of endoplasmic reticulum (ER)-induced 

stress genes in Panc-1 pancreatic cancer cells is dependent on Sp proteins. J. Biol. Chem. 

280:16508-16513. 

Abdelrahim M, Newman K, Vanderlaag K, Samudio I and Safe S. 2006. 3,3'-Diindolylmethane 

(DIM) and derivatives induce apoptosis in pancreatic cancer cells through endoplasmic 

reticulum stress-dependent upregulation of DR5. Carcinogenesis 27:717-728. 

Abdelrahim M, and Safe SH. 2005. Cyclooxygenase-2 inhibitors decrease vascular endothelial 

growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 

proteins. Mol. Pharmacol. 68:317-329. 

Abdou HE, Mohamed AA, Fackler Jr, JP. 2005. Synthesis and X-ray Structures of Dinulear 

and Trinuclear Gold(I) and Dinuclear Gold(II) Amidinate Complexes. Inorg. Chem. 44:166- 

168. 

Afriyie-Gyawu E, Mackie J, Dash B, Wiles M, Taylor J, Huebner H, Tang L, Guan H, Wang J-S, 

and Phillips TD. 2005. Chronic toxicological evaluation of dietary NovaSil clay in Sprague- 

Dawley rats. Food Additives & Contaminants. 22:259-269. 

Afriyie-Gyawu E, Mayura K, Wiles MC, Huebner HJ, Julian J, Fickey C and Phillips TD. 2005. 

Prevention of zearalenone-induced hyperestrogenism in prepubertal mice. J. Toxicol 

Environ. Hlth. Part A. 68:353-368. 

Anderson RC, Harvey RB, Byrd JA, Callaway TR, Genovese KJ, Edrington TS, Jung YS, 

McReynolds JL and Nisbet DJ. 2005. Novel preharvest strategies involving the use of 

experimental chlorate preparations and nitro-based compounds to prevent colonization of 

food-producing animals by foodborne pathogens. Poult. Sci. 84:649-654. 

Apte UM, Banerjee A, McRee R, Wellberg E and Ramaiah SK. 2005. Role of Osteopontin in 

Hepatic Neutrophil Infiltration during Alcoholic Steatohepatitis, Toxicol. Appl. Pharmacol. In 

press. 

Avila LA, Senseman SA, McCauley GN, Chandler JM and O’Barr JH. 2005. Effect of flood 

timing on red rice (Oryza spp.) control with imazethapyr applied at different rice stages. 

Weed Technol. 19:476-480. 

Avila LA, Lee DJ, Senseman SA, McCauley GN, Chandler JM and Cothren JT. 2005. 

Acetolactate synthase (ALS) activity in red rice ecotypes (Oryza spp.) and imidazolinone 

tolerant/resistant rice cultivars (Oryza sativa) in response to imazethapyr. Pest. Manage. 

Sci. 61:171-178. 

Ball JM, Mitchell DM, Gibbons T and Parr RD. 2005. Rotavirus NSP4: A multifunctional viral 

enterotoxin. Viral Immunology 18:27-40. 

Ball JM, Swaggerty CL, Pei CL, Cox VW, Lim W-S, Xu X, and Payne SL. 2005. The surface 

unit glycoprotein of equine infectious anemia virus exhibits signaling and exterotoxic activity. 

Virol. 333:132-144. 

Barhoumi R, Awooda I, Mouneimne Y, Safe S and Burghardt R. 2006. Effects of benzo-apyrene 

on oxytocin-induced Ca 2+ oscillations in myometrial cells. Toxicol. Lett. In press. 

Barrier M and Mirkes PE. 2005. Proteomics in Developmental Toxicology. Repro. Toxicol. 

19:291-304. 

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June 2006 

Bellum S, Thuett K, Taylor R and Abbott LC. 2005. Assessment of tissue concentrations of 

mercury in mouse brain tissue using different routes of administration of methylmercury and 

different tissue preparations. Toxicology Mechanisms and Methods. In Press. 

Bergbreiter DE, Simanek EE, Owsik I. 2005. New Synthetic Methods for the Formation of 

Basic, Polyvalent, Hyperbranched Grafts. J. Poly. Sci. A 43:4654-4665. 

Calabro P, Samudio I, Safe SH, Willerson JT and Yeh ET. 2005. Inhibition of tumor necrosis 

factor-a-induced endothelial cell activation by a new class of PPARg agonists: an in vitro 

study. J. Vascular Res. 42:509-516. 

Callaway TR, Morrow JL, Poole TL, Wallace FM, Anderson RC, Dowd SE, Edrington TS, 

Genovese KJ, Byrd II JA and Harvey RB. 2005. Environmental prevalence and 

persistence of E. coli, coliforms, and Salmonella spp. in outdoor swine wallows. Foodborne 

Path. Dis. 2:263-273. 

Campbell LD, Scott HM, Bischoff KM, Anderson RC and Harvey RB. 2005. Prevalence of 

Class I integrons and AMR gene cassettes among enteric bacteria found in multi-site grouplevel 

cohorts of humans and swine. J. Food Prot. 68:141-145. 

Chatterjee N, Kalaylioglu Z and Carroll RJ. 2005. A new paradigm of conditional-likelihoods for 

exploiting gene-environment independence in family based case-control studies. Genetic 

Epidemiology. 28:138-156. 

Chatterjee N and Carroll RJ. 2005. Semiparametric maximum likelihood estimation in casecontrol 

studies of gene-environment interactions. Biometrika, 92:399-418. 

Chen J, Mohamed AA, Abdou HE, Krause Bauer JA, Fackler Jr, JP, Bruce AE and Bruce 

MRM. 2005. Novel metallamacrocyclic gold(I) thiolate cluster complex: structure and 

luminescence of [Au 9 (μ-dppm) 4 (μ-p-tc) 6 ](PF 6 ) 3 . Chem. Commun. 1575-1577. 

Chen M-E and Pietrantonio PV. 2006. The short neuropeptide F-like receptor from the red 

imported fire ant, Solenopsis invicta Buren. Archiv. Insect Biochem. Physiol. 61:195-208. 

Chen M-E, Holmes SP and Pietrantonio PV. 2006. The glucose transporter 8 from the fire ant 

Solenopsis invicta Buren. Archiv. Insect Biochem Phys. 62:55-72. 

Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K, Safe S. 2005. Activation of 

Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl) methanes induces apoptosis 

through nuclear pathways. J Biol Chem. 280:24903-24914. 

Chintharlapalli S, Papineni S, Baek SJ, Liu S and Safe SH. 2005. 1,1-Bis(3'indolyl)-1-(pphenylsubstituted)methanes 

are Peroxisome proliferator-activated receptor g agonists but 

decrease HCT-116 colon cancer cell survival through receptor-independent activation of 

early growth response-1 and NAG-1. Mol. Pharmacol. 68:1782-1792. 

Chintharlapalli S, Papineni S, Konopleva M, Andreeff M, Samudio I and Safe S. 2005. 2- 

Cyano-3,12-dioxo-olean-1,9-dien-28-oic acid (CDDO) and related esters inhibit growth of 

colon cancer cells through peroxisome proliferator-activated receptor g-dependent and - 

independent pathways. Mol. Pharmacol. 68:119-128. 

Cho TM, Wild JR, Donnelly KC, Tiffany-Castiglioni E. 2005. Remediation of 

organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus 

hydrolase (OPH). J. Tox. Env. Health. In press. 

Contractor R, Samudio IJ, Estrov Z, Harris D, McCubrey JA, Safe SH, Andreeff M and 

Konopleva M. 2005. A novel ring-substituted diindolylmethane 1,1-bis[3'-(5- 

methoxyindolyl)]-1-(p-t-butylphenyl)methane inhibits ERK activation and induces apoptosis 

in acute myeloid leukemia. Cancer Res. 65:2890-2898. 

Corapcioglu MY, Vogel JR, Munster CL, Pillai SD, Dowd S and Wang S. 2005. Virus transport 

experiments in a sandy aquifer. Water, Air, Soil, Pollution. 1-19. 

Covington MD, Bayless KJ, Burghardt RC, Davis GE, Parrish AR. 2005. Ischemia-induced 

cleavage of cadherins in nrk cells: evidence for a role of metalloproteinases. Am J Physiol 

Renal Physiol. 289:280-288. 

Covington MD, Burghardt RC, Parrish AR. 2005. Ischemia-induced cleavage of cadherins in 

NRK cells requires MT-1-MMP (MMP-14). Am J Physiol Renal Physiol. 290:F43. 

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June 2006 

Dash B, Afriyie-Gyawu E, Huebner HJ, Porter W, Wang JS, Jolly PE and Phillips TD. 2006. 

Determinants of the variability of aflatoxin-albumin adduct levels in Ghanains. J. Toxicol. 

Environ. Hlth. Part A. In press. 

Dash B, Afriyie-Gyawu E, Huebner HJ, Porter W, Wang JS, Jolly PE and Phillips TD. 2006. 

Noninvasive identification of inter-individual variation in xenobiotic metabolizing enzymes: 

Implications for cancer epidemiology and biomarker studies. J. Toxicol. Environ. Hlth. Part 

A. In press. 

Dash B, Metz R, Huebner HJ, Porter W and Phillips TD. 2006. Molecular characterization of a 

monofunctional catalse from Hydra vulgaris. Gene. Submitted. 

Dash B, Metz R, Huebner HJ, Porter W and Phillips TD. 2006. Molecular characterization of 

phospholipid hydroperoxide glutathione peroxidases from Hydra vulgaris. Gene. Submitted. 

Dash B, Metz R, Huebner HJ, Porter W and Phillips TD. 2006. Molecular characterization of 

two superoxide dismutases from Hydra vulgaris. Gene. Submitted. 

Dash B, Metz R, Taylor J, Huebner HJ, Porter W and Phillips TD. 2006. Molecular 

characterization of a heat shock protein 70 from Hydra vulgaris. Gene. Submitted. 

Dees WL, Srivastava VK, and Hiney JK. 2005. Alcohol alters insulin-like growth factor-1 

activated Oct 2 POU gene expression in the immature female hypothalamus. J. Studies 

Alcohol. 66:35-45. 

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Graham SL, Barling KS, Waghela S, Scott HM and Thompson JA. 2005. Spatial distribution of 

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Konopleva M, Zhang W, Shi YX, McQueen T, Tsao T, Abdelrahim M, Munsell MF, Johansen M, 

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Kwak H, Metz RP, Schedin P and Porter W. 2006. Breast Tumor Suppressive Activity of the 

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Liang H and Wang N. 2005. Large sample theory in a semiparametric partially linear errors-invariables 

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Spiegelstein O, Gould A, Wlodarczyk B, Tsie M, Lu X, Le C, Troen A, Selhub J, Piedrahita JA, 

Salbaum JM, Kappen C, Melnyk S, James J and Finnell RH. 2005. Developmental 

consequences of in utero sodium arsenate exposure in mice with folate transport 

deficiencies. Toxicol. Appl. Pharmacol. 203:18-26. 

Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ and Finnell RH. 2005. 

Effects of dietary folate intake and folate binding protein 2 (Folbp2) on urinary speciation of 

sodium arsenate in mice. Env. Toxicol. & Pharmacol. 19:1-7. 

Spinka C, Carroll RJ and Chatterjee N. 2005. Analysis of case-control studies of genetic and 

environmental factors with missing genetic information and haplotype phase ambiguity. 

Genetic Epidemiology, 29:108-127. 

Steffensen MB, Hollink E, Bauer M, Simanek EE. 2006. The History of Triazine Dendrimers. J. 

Poly Sci. In press. 

Taneja-Bageshwar S, Strey A, Zubrzak P, Pietrantonio PV and Nachman R. 2005. Structureactivity 

relationships for insect kinins on expressed receptors from a tick (Acari: Ixodidae) 

and a mosquito (Diptera: Culicidae). Pestycydy 3:55-59 (Pesticides, Poland ISSN: 0208- 

8703; Institute of Industrial Organic Chemistry). 

Taneja-Bageshwar S, Strey A, Zubrzak P, Pietrantonio PV and Nachman R. 2006. 

Comparative structure-activity analysis of insect kinin core analogs on recombinant kinin 

receptors from Southern cattle tick Boophilus microplus (Acari: Ixodidae) and mosquito 

Aedes aegypti (Diptera: Culicidae) Archiv. Insect Biochem. Physiol. Especial issue, proofs 

available. In Press. 

Tang LS, Santillano DR, Miranda RC, Finnell RH. 2005. Role of folbp1 in the regional 

regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies. 

Seminars in Medical Genetics 135:48-58. 

Thompson JA, Brown SE, Riddle T, Seahorn JC and Cohen ND. 2005. Use of a Bayesian 

risk-mapping technique to estimate spatial risks for mare reproductive loss syndrome in 

Kentucky. American Journal of Veterinary Research 65:17-20. 

Tiffany-Castiglioni E, Venkatraj JS, Qian Y. 2005. Genetic polymorphisms and mechanisms 

of neurotoxicity: overview. Neurotoxicology. 26:641-649. 

25


June 2006 

Tomasewski MA, de Haan MA, Thompson JA and Jordan ER. 2005. The impact of cooling 

ponds in North Central Texas on dairy farm performance. Journal of Dairy Science 88:2281- 

2286. 

Twizere J-C, Samuel, S and Bernstein LR. 2006. Nucleolin binds specifically to an AP-1 DNA 

sequence and represses AP1-dependent transactivation and mRNA expression of the 

matrix metalloproteinase-13 gene, Molecular Carcinogenesis. In Press. 

Valles R, Rocha A, Cardon AL, Bratton GR and Nation JR. 2005. The Effects of the GABA A 

Antagonist Bicuculline on Cocaine Self-Administration in Rats Exposed to Lead During 

Gestation/Lactation. Pharmacology, Biochemistry, and Behavior. 80:611-619. 

Vanamala J, Cobb G, Turner ND, Lupton JR, Yoo KS, Pike LM and Patil BS. 2005. Bioactive 

compounds of grapefruit (Citrus paradisi cv Rio Red) respond differently to postharvest 

irradiation, storage and freeze drying. J. Agric. Food Chem. 53:3980-3985. 

Vanamala J, Leonardi T, Murphy ME, Taddeo SS, Patil BS, Pike LM, Chapkin RS, Lupton JR 

and Turner ND. 2006. Suppression of colon carcinogenesis by bioactive compounds in 

grapefruit. Carcinogenesis. In Press. 

Vanderlaag K, Samudio I, Burghardt R, Barhoumi R, Safe S. 2006. Inhibition of breast cancer 

cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'- 

dibromoDIM. Cancer Lett. 236, 198-212. 

Viveros L, Paliwal S, McCrae D, Wild JR, Simonian AL. 2005. A fluorescence-based biosensor 

for the detection of organophosphate pesticides and chemical warfare agents. Sensors and 

Actuators B:Chemical. SNB8896:1-7. 

Wales ME, Rodriguez M, Hua PJ, Goode TA and Wild JR. 2005. Modeling Allosteric 

Regulation of de nove Pyrimidine Biosynthesis in E. coli. Theoretical Biology. In 

Press. 

Wang J-S, Luo H, Billam M, Wang Z, Guan H, Tang L, Goldston T, Afriyie-Gyawu E, Lovett C, 

Griswold J, Brattin B, Taylor RJ, Huebner HJ and Phillips TD. 2005. Short-term safety 

evaluation of processed calcium montmorillonite clay (NovaSil) in humans. Food Additives 

& Contaminants. 22:270-279. 

Wang N, Carroll RJ and Lin X. 2005. Efficient semiparametric marginal estimation for 

longitudinal/clustered data. Journal of the American Statistical Association, 100:147-157. 

Weis MT, Brady M, Moore M, Crumley J and Stallone JN. 2005. Inhibiting long chain fatty acyl 

coA synthetase does not increase agonist-induced release of arachidonate metabolites from 

human endothelial cells. J. Vasc. Res. 42:275-283. 

White FJ, Ross JW, Joyce MM, Geisert RD, Burghardt RC, Johnson GA. 2005. Steroid 

regulation of cell specific osteopontin expression in the pregnant porcine uterus. Biol 

Reprod. 73:1294-1301. 

Widmer KW, Srikumar D and Pillai SD. 2005. Artificial Neural Networks to Accurately Identify 

Cryptosporidium Oocysts and Giardia Cysts Images. Applied and Environmental 

Microbiology. 71:80-84 

Wiles MC, Ake CL, Donnelly KC, McDonald TJ, Huebner HJ, Burghardt RC, and Phillips TD. 

2005. Matrix-immobilized organoclay for the removal of toxic contaminants from 

groundwater. Chemosphere. 59:1455-64. 

Wilkerson MK, Lesniewski LA, Golding EM, Bryan RM Jr, Amin A, Wilson E and Delp MD. 

2005. Simulated microgravity enhances cerebral artery vasoconstriction and vascular 

resistance through an endothelial nitric oxide mechanism. Am J Physiol Heart Circ Physiol 

288:H1652-H1661. 

Wlodarczyk BJ, Tang LS, Triplett A, Aleman F, and Finnell RH. 2005. Spontaneous neural 

tube defects in Splotch mice supplemented with selected micronutrients. Toxicol. Appl. 

Pharmacol. In Press. 

Woshner VM, Rosa C, Bratton G, Dehn L, Dau J, Blake J, and O’Hara TM. 2005. Necropsy 

Findings and Mineral Status Associated with a Caribou Mortality Event in the Western Arctic 

Herd of Alaska, 1999-2000. Marine Pollution Bulletin. In press. 

26


June 2006 

Yan Z, Chinta S, Mohamed AA, Fackler Jr, JP and Goodman DW. 2005. The Role of F- 

Centers in Catalysis by Au Supported on MgO. J. Am. Chem. Soc. 127:1604-1605. 

Yang W, Tiffany-Castiglioni E. 2005. The bipyridyl herbicide paraquat produces oxidative 

stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: relevance to the 

dopaminergic pathogenesis. J.Tox. Env. Hlth. In press. 

Zhang J, Zhu H, Yang W, Shaw GM, Lammer EJ, and Finnell RH. 2006. Phosphatidylethanolamine 

N-methyltransferase (PEMT) gene polymorphisms and risk of spina bifida. 

Am. J. Med. Genet. In Press. 

Zhang P, Smith R, Chapkin RS and McMurray DN. 2005. Dietary n-3 Polyunsaturated fatty 

acids modulate the Th1/Th2 balance towards the Th2 pole by suppression of Th1 

development. Journal of Nutrition 135:1745-1751. 

Zhang S, Li X, Burghardt R, Smith III R, Safe SH. 2005. Role of estrogen receptor (ER)α in 

insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells. J Mol 

Endocrinol. 35:433-447. 

Zhou G-D, Popovic N, Lupton J, Turner N, Chapkin R, Donnelly K. 2005. Tissue specific 

attenuation of endogenous DNA I-Compounds in rats by carcinogen azoxymethane: 

possible role of dietary fish oil in colon cancer prevention. Cancer Epidemiol Biomarkers 

Prev. 14:1230-1235. 

Zhu H, Curry S, Wen S, Shaw GM, Lammer EJ, Wicker N, Yang W, Jafarov T, and Finnell RH. 

2005. Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk 

factors for spina bifida and orofacial clefts? Am. J. Med. Genet. 135:274-277. 

Zhu H, Lu W, Laurent C, Shaw GM, Lammer EJ, and Finnell RH. 2005. Genes Encoding 

Catalytic Subunits of Protein Kinase A and Risk of Spina Bifida. Birth Defects Research A. 

73:591-596. 

Zhu H, Yang W, Zhang J, Shaw GM, Lammer EJ, and Finnell RH. 2005. Ile120Val 

polymorphism of the human PCMT1 gene is a genetic modifer of spina bifida risk. Birth 

Defects Res. A. In Press. 

Zhu JH, Zhu H, Finnell RH and Li Z. 2005. Variable Contribution of the MTHFR C677T 

polymorphism to non-syndromic cleft lip and palate risk in China. Am. J. Med. Genet. In 

Press. 

Ziprin RL, Hume ME, Andrews K, Droleskey RE, Harvey RB, and Sheffield CL. 2005. An 

atypical Campylobacter coli exhibiting unusual morphology. Current Microbiol. 51:1-4. 

BOOK CHAPTERS 

Anderson RC, Genovese KJ, Harvey RB, Callaway TR and Nisbet DJ. 2006. Preharvest food 

safety applications of competitive exclusion cultures and probiotics. Pp. 273-284. In: 

Probiotics in Food Safety and Human Health. Goktepe, I., Juneja, V.J., and Ahmedna, M. 

(ed.), Taylor and Francis, New York, USA. 

Ball JM, Parr RD and Schutt CE. 2006. Genetic, Structural and Functional Analyses of 

Rotavirus NSP4. In: Structure and Molecular Biology of Segmented Double-Stranded RNA 

Viruses, Nibert and Patton,eds. Horizon Scientific Press, In press. 

Finnell RH, Cabrera R and Spiegelstein O. 2005. Gene Expression Profiling in Developmental 

and Reproductive Toxicology. In: Developmental and Reproductive Toxicology: A Practical 

Approach. 2nd Ed. R.D. Hood, Ed. CRC Press. pp. 621-646. 

Payne SL, Lim, W-S, Fuller GJ, and Ball JM. 2006. Equine Infectious Anemia Virus as a Model 

for Lentiviral Pathogenesis. In: In Vivo Models of HIV Disease and Control, Bendrenelli, M., 

Friedman, H., eds. Kluer Academic/Plenum Publishers, pp 365-386. 

Safe S. 2006. Polychlorinated biphenyls. In: Environmental and Occupational Medicine, 4th 

ed. (W. Rom, ed.), Lippincott-Raven Publishers, Philadelphia. 

Schroeder F, Atshaves BP, Gallegos AM, McIntosh AL, Liu JCS, Kier AB, Huang H, and Ball 

JM. 2005. Lipid Rafts and Caveolae Organization. In: Advances in Molecular and Cell 

Biology, Vol. 36, Chapter 1, pp 1-34, Bittar, E.E., series ed. 

27


June 2006 

Spencer TE, Hayashi K, Hu J, Carpenter KD. 2005. Comparative developmental biology of the 

mammalian uterus. In: Schatten, G (ed.) Current Topics in Developmental Biology, Volume 

68. Amsterdam:Elsevier; pp. 85-122. 

Stillwell W, Shaikh SR, LoCascio D, Siddiqui RA, Seo J, Chapkin RS and Wassall SR. 2006. 

Docosahexaenoic acid. An important membrane-altering omega-3 fatty acid. In: Frontiers 

in Nutrition Research: New Research, Nova Science Publishers, Inc, Hauppauge, NY. 

Swanson HI, Ray SS, Hoagland M, Thompson ED, Zheng X and Tian Y. In: Experimental 

approaches for the study of cytochrome. P450 (Humana) (In press). 

Tiffany-Castiglioni E, Venkatraj V, Qian y, Wild JR. 2006. In vitro models for testing 

organophosphate-induced neurotoxicity and remediation. In Toxicology of Organophosphate 

& Carbamate Compounds. Ed. Ramesh C. Gupta. Elsevier Press, Amsterdam..22:315-338. 

SUMMARY 

Peer Reviewed Book Chapters 

Articles 

Total Number 206 10 

Collaborative Number 40 2 

% Collabortive 19.4% 20% 

Graduate Trainee First Author 41 N/A 

% Trainee Authored 19.9% N/A 

28


June 2006 

APPENDIX E – Grant Support 

Funding 

Institution 

Grant No. PI Title IFT Collaborators Total 

Direct 

Award 

USDA/CSREES TEX09104 Ball Role of plasma membrane 

microdomains in EIAV 

signaling events: A new 

target of intervention 

NIH 

5R01GM062326- 

05 

Ball 

Transport and lipid 

interactions of a novel 

enterotoxin 

USDA/CSREES TEX09096 Ball/Payne Effects of equine infectious 

anemia virus on expression 

of cytokines and 

chemokines in equine cells 

Colgate-Palmolive 

Grants for 

Alternatives 

Research 

N/A Barhoumi Early Toxicity Screening for 

Drug Development in 

Immature Neural Cells 

USDA 00-35203-9137 Bazer Roles of Fibroblast Growth 

Factor-7 in Uterine Biology 

and Pregnancy in Pigs. 

Texas A&M 

Univeristy 

N/A Bazer Training Grant in 

Reproductive Biology 

NIH/NICHD 2 R01 HD32534 Bazer Ovine Interferon-Tau 

Regulates Uterine 

Hormone Receptors 

Max and Victoria 

Dreyfus 

Foundation 

N/A Bernstein YB-1, a new AP-1 DNA 

binding transrepressor 

TAMHSC N/A Bernstein YB-1, a new AP-1 DNA 


WMA Foundation N/A Busbee Methods to Study 

Chemicals that Alter Gene 

Expression 

NSF/DMS 216275 Calvin MRI: Development of a 

High Density, High 

Performance Beowulf 

Cluster 

29 

Annual 

Direct 

Award 

Funding 

Period 

7/14/05- 

9/30/06 

$1,135,860 $227,172 6/1/01- 

5/31/06 

5/5/05- 

9/30/06 

Castiglioni $39,326 $39,326 1/1/06- 

12/31/06 

Spencer $633,000 $190,000 5/1/05- 

4/30/08 

Burghardt, Dees, 

Safe, Spencer 

$198,373 $99,187 10/1/05- 

9/30/06 

Spencer $1,309,500 $261,900 2/28/01- 

2/27/06 

$15,000 $15,000 6/1/05- 

5/31/06 

$15,000 $15,000 2/1/05- 

1/31/06 

7/1/01- 

6/30/06 

$405,202 $81,040 8/1/02- 

7/31/07


June 2006 

CDC-Centers for 

Excellence 

NCI 

NIH 

U50/CCU613- 

232 

R01 CA092670- 

05 

2R37 

CA057030-17 

Canfield 

Carozza 

Carroll 

National Birth Defects 

Prevention Study-Texas 

Risk of Childhood Cancers 

Associated with Agricultural 

Pesticide Use 

Measurement Error, 

Nutrition, and Breast/Colon 

Cancer 

NIH R25 CA 90301 Carroll Training Program in 

Biostatistics, Bioinformatics 

and Nutrition 

NIH/NCI R25T CA90301 Carroll Nutrition, Biostatistics and 

Bioinformatics 

AICR 05A081 Chapkin Use of novel genetic 

mouse models to 

investigate the health 

benefits of folate in colon 

USDA CSREES 2003- 

00818 

USDA Special 

Grant-Designing 

Foods for Health 

CSREES 2005- 

30741 

Chapkin 

Chapkin 

cancer. 

Nutritional modulation of 

immunity: Regulation of 

Th1/Th2 responses. 

Antiinflammatory effects of 

omega-3 fatty acids: 

Potential enhancement by 

citrus flavonoids 

NIH R01 CA59034 Chapkin Colonic cytokinetics and 

cell signaling: dietary effect 

Scott & White 

Clinic TAMHSC 

N/A Chapkin Non-invasive detection of 

human epithelial cell gene 

expression profiles using 

exfoliated colonocytes: 

development of robust 

classifiers for colon cancer 

and pre-cancerous 

inflammatory bowel 

disease. 

NIH Subcontract 26XS039A Chapkin The effects of high legume 

low glycemic index on 

insulin resistance and 

inflammation in patients at 

high risk for colorectal 

adenoma recurrence. 

Finnell $844,725 $168,945 10/1/02- 

9/30/07 

Sherman 9/3/01- 

2/28/06 

$1,125,000 $140,625 9/01/05- 

8/31/08 

Chapkin $500,000 $166,667 12/1/05- 

11/30/08 

Turner $2,469,800 $493,960 8/1/01- 

7/31/06 

Finnell $150,000 $75,000 8/1/05- 

7/31/07 

$225,000 $75,000 7/1/03 - 

6/30/06 

$49,000 $49,000 10/1/05- 

9/30/06 

$1,000,000 $200,000 5/1/03 - 

6/30/08 

$40,000 $40,000 5/1/05- 

4/30/06 

$100,000 $100,000 10/1/05- 

9/30/06 

30


June 2006 

NIH-NINDS MSM 

R01-NS54252- 

01 

Choe 

Multiscale imaging, 

analysis, and integration of 

brain networks 

NIH R01 HL072989 Davis Regulation of vascular tone 

and calcium channels by 

integrins 

NIH R01 HL071796 Davis Regulation of arteriolar 

tone and K channels by 

NIEHS 

NIH/NHLBI 

CDC 

R01 ES013143- 

01 

1 R01 HL- 

077224-01 

200-2005-M- 

12814 

DHHS-HRSA 5 A03 HP 01192- 

03-00 

DHHS-HRSA 6U55RH06350- 

01-02 

Dees 

Delp 

Donnelly 

integrins 

Actions of Manganese on 

Neuroendocrine 

Development 

Aging, Estrogen, and 

Coronary Endothelial 

Function 

Longitudinal Variability in 

Urinary Pesticide 

Metabolites Among 

Children 

Abbott $966,000 $322,000 9/1/05- 

7/31/08 

Wilson, E. $34,000 $8,500 4/1/03- 

3/31/07 

Wilson, E. $34,000 $8,500 8/1/03- 

7/31/07 

$672,000 $168,000 8/15/01- 

7/31/06 

Stallone $20,403 $6,801 4/1/05- 

3/31/08 

$25,000 $25,000 6/30/05- 

7/7/06 

Donnelly Public Health Traineeship $10,365 $2,591 7/1/02- 

6/30/06 

Donnelly 

Border Environmental 

Health Coordination 

USEPA RD 83068401-0 Donnelly Issues in Human Health 

Assessment: Novel 

Mechanistic Approaches in 

Human Health 

USEPA X4-96608801-0 Donnelly Border 2012-Childhood 

Exposure & Susceptibility 

to Pesticides in 

Texas/Mexico Border 

Region 

Welch Foundation N/A Fackler New Gold Complexes with 

Nitrogen Ligands 

NIH/NIDCR 

1R01DE016315- 

01A1 

Finnell 

Genetic regulation of folate 

responsive birth defects. 

NSF-NTE Ford/Shantz Engineering on 

Nanospaces: Hybrid 

Membranes for 

Environmentally Important 

Separations 

NIH P01 GM 71790 Gerlt Deciphering Enzyme 

Specificity 

31 

$31,271 $10,424 9/1/05- 

8/31/08 

$371,681 $92,920 1/31/03- 

1/31/07 

$26,265 $26,265 10/1/05- 

9/30/06 

$210,000 $70,000 2004- 

2007 

$1,250,000 $250,000 8/1/05- 

4/30/10 

Simanek $410,000 $136,667 9/1/03- 

8/31/06 

Raushel $400,000 $80,000 7/1/04- 

6/30/09


June 2006 

NIH-NIA 

Super Jake 

Foundation 

NIH-NHLBI 

RO1-AG007805- 

9 

Griffith 

Physiology of Cholinergic 

Basal Forebrain Neurons 

06-60043 Harris Evaluation of Citrus 

Limonoids Against 

Neuroblastomas-Animal 

studies 

1R01HL080415- 

01 

Humphrey 

Ex vivo delineation of 

mechanisms of cerebral 

vasospasm 

NIH R01 HL-64372 Humphrey Histo-mechanics & Biology 

of Remodeling of 

Hypertension 

NIH/Bioengineering 

Research 

Partnership 

1 R01 HL-64372- 

01 

Humphrey 

Histo-Mechanics & Biology 

of Remodeling in 

Hypertension 

NIH Johnson Enhancement of K-12 

Science Education – 

Graduate Training Program 

NIH/NIA 

1 R01 AG- 

19327-01 

Knowlton 

Aging, Estrogen and Heat 

Shock Proteins in 

Myocardial Ischemia 

NIH R01-AI51593-02 Leibowitz Interaction of MHV RNA 

with mtHSP70 and m- 

aconitase 

NSBRI NPFR00402 Lupton Nutritional 

Countermeasures to 

Radiation-Enhanced Colon 

Cancer 

NSBRI E00064 Lupton A graduate education 

program focusing on space 

life sciences 

NIH/NCI 

5 R01 CA82907- 

04 

Lupton 

Diet, Apoptosis and Colon 


USDA 2003-00818 McMurray Nutritional modulation of 

immunity 

NIH R01 AI15495 McMurray Dietary deficiencies and 

tuberculosis vaccine 

efficacy 

NIH/NIAID T32 AI052072 McMurray Mechanistic studies at the 

host-pathogen interface 

NIH NS041548 Miranda Learning within the spinal 

cord: clinical implications 

Abbott $1,000,000 $200,000 9/1/03 - 

8/31/08 

Porter $61,000 $61,000 11/05- 

10/06 

Wilson, E. $1,235,000 $308,750 4/1/05- 

3/31/09 

Wilson, E. $3,001,599 $600,320 9/1/01- 

8/31/06 

Stallone $2,158,699 $431,740 9/24/01- 

8/31/06 

Wild 9/1/04 – 

8/31/08 

Stallone $875,000 $175,000 4/1/01- 

6/30/06 

Abbott 9/1/03 - 

8/31/08 

Turner, Chapkin, 

Carroll 

$1,329,516 $235,312 10/1/04- 

9/30/08 

Turner $72,690 $48,460 11/01/04- 

5/31/06 


Carroll 

$900,000 $225,000 2/1/01- 

1/31/07 

Chapkin $290,846 $96,949 9/1/03 - 

8/31/06 

Chapkin $1,000,000 $200,000 2/1/05 - 

1/31/10 

Ball $797,684 $159,537 9/1/03- 

8/30/08 

$373,705 $258,138 9/1/05- 

8/31/10 

32


June 2006 

NIH AA13440 Miranda Fetal Alcohol Exposure and 

neurodevelopment 

NIEHS P30 ES09106 Mirkes Center for Environmental 

and Rural Health 

NIEHS U19 ES11387 Mirkes Toxicogenomic Pathway 

Analysis of Sensitive and 

Resistant Mammalian 

Models for 

Neurodevlopmenbtal 


NIEHS R01 ES08744 Mirkes 70KDHSPs-Modulators of 

Developmental Toxicity 

NIH 

Engelhard 

Chemical 

Corporation 

Engelhard 

Chemical 

Corporation 

USAID-ALO 

USDA-CSREES- 

NRI 

1 R21 

AG024179 

Parrish Age-Dependent Loss of N- 

Cadherin in Rat Proximal 

Tubules 

TAES 404300 Phillips Development of 

enterosorbents 

TAES License 

Agreement 

USAID (Peanut 

CRSP) RF 

453421 

Phillips 

Phillips 

Pietrantonio 

Method for inactivating 

mycotoxins in the 

gastrointestinal tract of 

animals 

Sustainable enterosorbent 

strategies for the protection 

of African populations from 

aflatoxin 

Functional characterization 

and target validation of tick 

(Boophilus microplus) G 

protein-coupled receptors. 

Sherman $393,750 $175,000 9/1/03 - 

8/31/08 

Abbott, Ball, 

Bernstein, 

Burghardt, Busbee, 

Calvin, Carroll, 

Chapkin, Dees, 

Donnelly, Finnell, 

Miranda, Parrish, 

Phillips, Porter, 

Ramaiah, Safe, 

Sherman, Spencer, 

Spiegelman, Tian, 

Tiffany-Castiglioni, 

Turner, Wang, Wild, 

E. Wilson 

$4,980,523 $1,000,000 4/1/02- 

3/31/07 

$216,470 $48,229 8/30/01- 

8/31/06 

$800,000 $200,000 9/1/04- 

11/30/06 

Burghardt $200,000 $100,000 9/01/03 - 

8/31/06 

$201,032 $50,258 11/1/03- 

10/31/07 

$54,086 $20,252 Recurren 

t Funding 

$583,622 $54,982 8/1/01- 

7/31/06 

10/1/03- 

9/30/06 

33


June 2006 

TAMU-Fire Ant 

Legislative Initiative 

Pietrantonio 

/ Vinson 

Developing the concept of 

reproductive control as a 

method to reduce the 

Imported Fire ant 

populations 

NASA Pillai Electron beam sterilization 

of spacecraft components 

TAMU-Conacyt 

Program 

Pillai 

Quantifying health risks in 

Mexico associated with 

contaminated fruits and 

vegetables via pathogens 

in irrigation water 

USDA-CSREES Pillai (Co-PI) Microfluidic system for 

capture and concentration 

of microbial contaminants 

in drinking water 

NIH 

1R01CA111551- 

01A1 

Porter 

Singleminded-2 in 

Mammary Gland and 

Breast Cancer 

NIAAA F31AA015232 Prock The Effects of Alcohol on 

Cell Fate Heterogeneity 

Veterinary 

Pathobiology 

2006- 

2007 

$900,000 $300,000 9/1/04- 

8/31/07 

9/1/05- 

9/1/06 

$126,550 $42,183 8/1/03- 

8/1/06 

$822,000 $158,000 7/1/05- 

4/3010 

Miranda 5/1/05- 

4/31/07 

135303-1000 Ramaiah Alcoholic Hepatitis $200,000 $50,000 7/1/02- 

6/30/06 

NIH R01 GM 68550 Raushel Enzymatic Detoxification of 

Chemical Warfare Agents 

NIH R01 DK 30343 Raushel Mechanism and Control of 

Urea Biosynthesis 

Welch Foundation A-840 Raushel Enzyme Reaction 

Mechanisms 

NIH P30 HL66398-01 Rosenquist Folic Acid and 

Homocysteine: 

Mechanisms of Heart 

Defects 

NIEHS R01-ES04176 Safe Effects of 2,3,7,8-TCDD on 

Estrogenic Responses 

NIEHS R01-ES09253 Safe Mechanism of Growth 

Factor-Estrogen Receptor 

Crosstalk 

7/1/03- 

6/30/07 

9/1/01- 

8/31/06 

$150,000 $50,000 6/1/05- 

5/31/08 

Finnell $929,825 $185,965 9/1/01- 

8/31/06 

Burghardt $750,000 $150,000 1/1/02- 

12/31/07 

Burghardt $750,000 $150,000 9/1/01 - 

8/31/07 

34


June 2006 

NIEHS T32-ES07273 Safe Toxicology of 

Environmental 

Contaminants 

NIEHS P42-ES04917 Safe Procedures to Assess the 

Hazard of a Superfund Site 

(Total Program Project 

Grant) 

NIH R01-CA104116 Safe Coactivation of Estrogen 

Rreceptor a/Sp1 

NIH R01-CA112337 Safe Colon Cancer Inhibition by 

a Class of PPARg Agonists 

NIH R01-CA108718 Safe Inhibition of Pancreatic 

Cancer by PPARg Agonists 

USDA-CSREES- 

NRI 

Albaugh 

Corporation 


Excellence 

NIH/NINDS 

2003-35212- 

13298 

Scott 

Transmission Dynamics of 

Antimicrobial Resistance in 

Integrated Animal and 

Human Populations 

Senseman Determination of secondary 

drift differences between 

chemical formulations 

U59/CCU913241 Shaw Genetic and Environmental 

Risks of Common Birth 

R01 NS050249- 

01 

Shaw 

Defects 

Gene-nutrient etiologies of 

neural tube defects 

Burghardt, 


Johnson, Phillips, 

Castiglioni, Wild 

Burghardt, 


Phillips 

$1,100,000 $133,554 7/01/97- 

6/30/07 

$3,163,000 $1,054,333 4/1/05- 

3/31/08 

Burghardt $450,000 $150,000 4/1/04- 

3/31/07 

Burghardt, Porter $875,000 $175,000 1/1/05- 

12/31/09 

Porter $875,000 $175,000 11/1/04- 

10/31/09 

Harvey 9/1/03- 

8/31/07 

2005- 

2006 

Finnell $1,124,335 $224,867 10/1/02- 

9/30/07 

Finnell 9/1/05- 

8/31/10 

Welch Foundation Simanek Molecular Recognition $150,000 $50,000 6/1/02- 

5/31/05 

NIH Simanek Molecular Recognition in 

Dendrimers 

NSF-CCLI Simanek Anchoring Organic 

Chemistry in Context 

NSF 3134-03 Auburn Simonian Nanoparticle-based 

Biosensor for Direct 

Detection of 

Organophosphate 


and Neurotoxic Pesticide 

USDA NRI 2005-01476 Spencer Biological Functions of 

Galectin-15 in the Ovine 

Uterus 

35 

$1,078,500 $269,625 8/1/02- 

7/31/06 

$149,998 $49,999 1/27/06- 

1/14/09 

Wild $650,000 $216,667 10/1/03- 

9/1/06 

Burghardt $275,000 $91,667 9/1/03- 

4/30/06


June 2006 

BARD US-3199-OCR Spencer Placental Lactogen 

Enhances Production 

Efficiency in Sheep 

USDA NRI 2001-02259 Spencer Role of Endometrial Glands 

in Uterine Function 

NIH 1R01 HD38274 Spencer Mechanisms Regulating 

Uterine Morphogenesis 

NIH/NHLBI 

1R01 HL- 

080402-01A1 

Stallone 

Nongenomic Mechanisms 

of Androgens in the 

Vascular Wall 

NIH 5R03CA106080 Thompson The Role of Pesticide 

Dispersion Within Texas 

Watersheds in Childhood 

Cancers 

NIEHS 

5R01ES009859- 

07 

Tian 

Regulation of cyp1a1 by Ah 

receptor and NFkB 

interaction 

USDA/ARS 58-5430-5-339 Turner Sorghum Bioactive 

Constituents as Colon 

Cancer Chemoprotectants 

AICR 05B094 Vanamala Fish oil and pectin 

enhances apoptosis in 

colonocytes via inhibition of 

PGE2 and PPAR delta 

signaling and promotion of 

death receptor pathway. 

NCI Wang, LH Non-invasive optical 

detection of skin cancer 

NCI 

5R01CA074552- 

09 

Wang, N. 


Missing Data and 

Semiparametrics. 

NIH R01 CA74552 Wang, N. Measurement Error, 

Missing Data and 

Semiparametrics 

NIH/NIA 

1 R03 AG- 

022614-01 

Weis 

Estrogen, Fatty Acyl CoA, 

& NOS Function in 

Hypertension 

Welch Foundation Welch A-915 Wild Chemical Restructuring of 

Allosteric Interactions in 

Regulatory Enzymes 

$150,000 $50,000 9/1/00- 

5/31/06 

Burghardt $218,000 $72,667 10/1/03- 

6/30/06 

Burghardt $536,000 $134,068 10/1/05- 

9/30/06 

$1,140,740 $285,185 4/1/06- 

3/31/10 

$436,500 $145,500 9/1/03- 

8/31/06 

$950,000 $190,000 2/1/00- 

7/31/08 

9/1/05 – 

6/30/07 

Turner 1/2/06 – 

1/1/08 

Wang, N. $1,800,000 $360,000 9/01/04- 

8/31/09 

$631,000 $63,100 4/21/97- 

3/31/07 

Chapkin $631,000 $315,500 8/1/05- 

7/31/07 

Stallone $75,000 $25,000 9/1/03- 

8/31/05 

$600,000 $200,000 1/01/03- 

5/31/06 

36


June 2006 

Office of Naval 

Research 

N00014-02-1- 

0536 

Wild (Co-PI) 

Summer Undergraduate 

Research Experiences— 

Multi-University Research 

Consortium: Research 

Leadership for the 21 st 

Century 

NIH-NIAID 1 R21 AI55918 Wild (Co-PI) Targets for Drug Design in 

Flaviviral Infection 

American Heart 

Association, Texas 

Affiliate Grant-in- 

Aid 

Muscular 

Dystrophy 

Association 

NIH 

Wilson, E. Matrix-dependent 

modulation of SRFmediated 

transcription by 

cyclic stretch in vascular 

smooth muscle 

MDA3681 Wilson, E. Arterial remodeling in 

mouse models of muscular 

dystrophy 

1 R21 

EB004106-01 

Wilson, E. 

Fibrillin-1 and pressureinduced 

arterial remodeling 

USDA 2003-03243 Wu Improve growth of sowreared 

piglets by enhancing 

arginine synthesis 




USDA NRI 2001-02166 Wu Progesterone Regulation of 

Placental Nitric Oxide and 

Polyamine Synthesis in 

Pigs 

10/1/03 - 

09/1/07 

7/1/03- 

6/1/06 

$130,000 $65,000 7/01/05- 

6/30/07 

$253,715 $84,550 1/01/04- 

12/31/06 

$275,000 $125,000 1/01/04- 

12/31/06 

Spencer $230,850 $76,000 4/1/98- 

3/31/07 

Spencer $230,850 $76,000 9/1/03- 

8/31/06 

Spencer $50,000 $10,000 9/30/01- 

8/31/06 

37


June 2006 

APPENDIX F – Faculty Awards 

Robert C. Burghardt 

Texas A&M University Agriculture Program Vice Chancellor’s Award in Excellence for Team 

Research, 2005 

Robert S. Chapkin 

Sigma Xi Distinguished Scientist Award, Texas A&M University Chapter, 2006 

Texas A&M University Faculty Fellow, 2001-2005 

Timothy D. Phillips 

Texas A&M University Association of Former Students Distinguished Achievement Award in 


Bush Award for Excellence in International Research, 2005 

Patricia V. Pietrantonio 

Sloan Foundation Scholar, 2006 

Texas A&M Experiment Station Fellow, 2006 

Frank K. Raushel 

Davidson Professor of Science, 2005 

Stephen H. Safe 

Texas A&M University Association of Former Students Distinguished Achievement Award in 


Texas A&M Health Science Center Regents’ Professor, 2006 

Scott A. Senseman 

CAPES (Fundação Coordenação de Aperfeiçoamento de Pessoal de Nivel Superior) 

Visiting Professor Fellowship, August 2005 - February 2006 

Texas Cooperative Extension Superior Service Award (team award), 2005 

Outstanding Paper in Weed Technology for the manuscript “Sciumbato, A.S., J.M. 

Chandler, S.A. Senseman, R.W. Bovey, and K.L. Smith. 2004. Determining exposure 

to auxin-like herbicides II. Practical application to quantify volatility. Weed Technol. 

18:1135,” 2005 

Finalist for Governor’s Award in Environmental Excellence for Atrazine Abatement Project, 

Team members Dr. Monty Dozier and Dr. Paul Baumann, 2005 

Thomas E. Spencer 

Sigma Xi Young Investigator Award, 2005 

Texas A&M University Agriculture Program Vice Chancellor’s Award in Excellence for 


Texas A&M University Agriculture Program Vice Chancellor’s Award in Excellence for Team 


Clifford Spiegelman 

Chance Lecturer, American Statistics Association, 2005 

James R. Wild 

Elected International Fellow for IUPAC 

38


June 2006 

APPENDIX G - Presentations 

Domestic Presentations 

Louise C. Abbott 

University of Texas, Southwestern Medical School, August 17, 2005. Invited presentation titled, 

“Life and death of cerebellar granule cells in calcium channel mutant mice”. 


Barhoumi R, A Awooda, SH Safe, RC Burghardt. Reversal of benzo-[a]-pyrene on oxytoxininduced 

Ca2+ oscillations in human myometrial PHM1-41 cells. 44 th Annual Meeting of the 

Society of Toxicology, New Orleans, LA, March 6-10, 2005 

Pulido M, K Bayless, R Burghardt, G Davis, AR Parrish. Ischemia-induced cleavage of 

cadherins in NRK cells: evidence for the role of MT1-MMP. 44 th Annual Meeting of the 


Chintharlapalli S, S Papineni, R Burghardt, S Safe. Identification of Nur77 agonists that induce 

apoptosis and inhibit cancer survival through nuclear pathways. 44 th Annual Meeting of the 


Johnson GA, RC Burghardt. Secreted Phosphoprotein-1 (Osteopontin) contributes to conceptus 

attachment and decidual angiogenesis in mice. Gordon Research Conference on Small 

Integrin-Binding Proteins, Big Sky, MT, September 11-16, 2005. 

Banerjee A, RC Burghardt, GA Johnson, FJ White, SK Ramaiah. Temporal expression and 

localization of osteopontin mRNA and protein in the rat alcoholic steatohepatitis model. 

American College of Toxicology annual meeting, Williamsburg, VA, November 6-9, 2005. 


Invited talk entitled Dietary lipids, chronic inflammation and colon cancer: an n-3 PUFA 

perspective.” Mead Johnson Nutritionals, Evansville, IN, January 7, 2005. 

Invited talk entitled “Chemoprotective/anti inflammatory fatty acids: implications of lipid 

microdomains”. Department of Nutrition, University of North Carolina, Chapel Hill, NC May 

19, 2005. 

Invited talk entitled “Noninvasive profiling of intestinal gene expression by targeting exfoliated 

cells.” Division of Gastroenterology, Scott & White Hospital, Texas A&M Health Science 

Center, Temple, TX, September 27, 2005. 

Invited talk entitled “Membrane altering properties of omega-3 fatty acids” at the Signaling 

Defects in Aging Immune Cells Symposium, NIH, October 24-25, 2005. 

Invited talk entitled “How folic acid protects colon cells from cancer” at the Center for 

Environmental and Rural Health symposium on “Folic acid: from prevention to intervention. 

How a B-vitamin can impact human health”, Texas A&M University, College Station, TX, 

December 16, 2005. 

Invited talk entitled “Why are Omega -3 fatty acids chemo-protective?” at the M.D. Anderson 

Cancer Center, Integrative Medicine Program Lecture Series, February 16, 2006. 

Kirby C. Donnelly 

Environmental Protection Agency, Dallas. Jan. 26, Sept. 28 and Oct. 19, 2005; Feb. 8, 2006 

South Texas Environmental Education and Research, Laredo. Monthly, 2005 and 2006 

Agency for Toxic Substances and Disease Registry, Atlanta. Feb. 16, 2005 

Office of Special Programs, Public Health, Grand Rounds. March 24, 2005 

Binational Health Symposium, Laredo. June 2005 

International Neural Tube Defects Conference, Indian Wells, CA. Sept. 2005 

L International Conference on Environmental Mutagens, San Francisco, CA. Sept. 2005 

39


June 2006 

aredo Department of Health, Laredo. Oct. 14, 2005 

Community meetings, Laredo. October and December, 2005 

Caldwell Junior High. Jan. 6, 2006 

John P. Fackler 

TAMU College of Veterinary Medicine, March 2, 2006, “Ethics in Science” 

Harvard- MIT Monthly Colloquium, (at MIT) April 26, 2006, “New Gold Chemistry with Nitrogen 

Ligands” 

University of Northern, Illinois, April 11, 2005, “Gold - An Old Element with a new Chemistry.” 

University of Texas at Arlington, April 26, 2005, “Gold - An Old Element with a new Chemistry.” 

Texas A&M University, Monie Ferst Lecture, “Reminiscences of Cotton’s educational leadership 

from the late 1950's and later” Oct. 22, 2005. 

Texas A&M University, Toxicology program, “Heavy Elements and Murder”, Halloween, October 

31, 2005. 

“Developing a Quality Enhancement Plan”, (with Marilee Bresciani) Southern Association of 

Colleges and Schools, Atlanta, Dec. 5, 2005. 

Roger B. Harvey 

Allen D. Leman Annual Swine Conference (University of Minnesota), St. Paul, MN, Sept. 17-20, 

2005. 

Gladys Y. Ko 

How many chickens does it take to change a light bulb? (Circadian regulation of L-type voltagegated 

calcium channels in retina photoreceptors). Southeastern and Central Texas Society 

for Clocks annual conference; January 27, 2006; TAMU. 

Protein expression and somatostatin modulation of calcium channels are under circadian control 

in chick retina photoreceptors. 2006 Association for Research in Vision and Ophthalmology 

(ARVO) annual meeting; May 04, 2006; Fort Lauderdale, FL. 

Circadian regulation of retina photoreceptor physiology: Using chick retina as a model to study 

macular degeneration related retina diseases. May 19, 2006 Spring Neuroscience 

symposium; TAMU. 

Philip E. Mirkes 

Invited lecture. “Apoptosis and Birth Defects” Texas A&M Health Science Center, College of 

Medicine. College Station, TX, January 2005. 

Invited lecture. University of Texas at Austin, Pharmacology and Toxicology Division. 

Austin, TX, October 2004. 

Invited lecture. “Regulation of Teratogen-induced Cell Death in Mouse Embryos.” 

University of Louisville Health Science Center, Dept. of Molecular, Cellular and 

Craniofacial Biology. Louisville, KY, May 2006. 

Alan R. Parrish 

Pulido M, K Bayless, R Burghardt, G Davis, AR Parrish. Ischemia-induced cleavage of 

cadherins in NRK cells: evidence for the role of MT1-MMP. 44 th Annual Meeting of the 


MT1-MMP (MMP-14) is Required for Ischemia-Induced Cadherin Cleavage in Normal Rat 

Kidney (NRK) Cells. Department of Pharmacology, College of Medicine, Midwestern 

University, Downers Grove, IL. Sept. 2005. 

MT1-MMP (MMP-14) is Required for Ischemia-Induced Cadherin Cleavage in Normal Rat 

Kidney (NRK) Cells. Cardiovascular Research Institute, Texas A&M University System, 

College Station, TX. Oct. 2005. 

40


June 2006 

Age-Related Molecular Mechanisms of Acute Renal Failure. Symposium “Targets of Toxicant 

Sensitivity in Aging.” Federation of American Societies for Experimental Biology, San 

Francisco, CA. Apr. 2006. 


Massachusetts Institute of Technology (MIT), Applied Biology and Chemistry 

Frito-Lay, Applied and Basic Research Section 

Department of Pharmacology and Toxicology, School of Medicine, TAMU 

Department of Pharmacology and Toxicology, UTMB, Galveston, TX 

Invited Speaker, The World Food Prize, Des Moines, IA, 2005 

Technical Conference of the IFT (Institute of Food Technologists) 

Society of Toxicology, New Orleans, LA, March 2005 

Gulf Coast Chapter of the Society of Toxicology, Austin, TX, October 2005 

Society of Toxicology, San Diego, CA, March 2006 


Monitoring for Bollworm (Helicoverpa zea) Pyrethroid Resistance in Texas 2004. Proceedings 

Beltwide Cotton Conferences. New Orleans, LA, January 4-7, 2005, 

Extension Entomology Professional Improvement Conference. Topic 1: Insecticide resistance 

theory and its application to management of Bollworm in Texas. Topic 2: Neonicotinoids: 

diversity and mode of action. New Braunfels, TX, March 21-24, 2005. 

“How to recruit faculty for diversity” and panel member for the Department Heads’ Orientation. 

TAMU, College Station, TX, Sept 2005. 

Pietrantonio, P.V., T. Junek, et al. “Bollworm (Helicoverpa zea) resistance monitoring in Texas 

2005. 17 th Annual Texas Plant Protection Conference. College Station, November 30-Dec. 

1, 2005. 

Invited presentation. H. zea trends in Bt cotton and sorghum: recent results recommending 

high-dose pyrethroids in Texas. Meeting of the North American H. zea pyrethroid resistance 

working group. Ft. Lauderdale, FL, Dec. 16 2005. 

Pietrantonio, P.V., T. Junek, R. Parker, et al. Monitoring for pyrethroid resistance in bollworm 

(Helicoverpa zea) in Texas- 2005. Proc. Cotton Beltwide Conferences. San Antonio TX, 

Jan.3-6 2006. 

Resistance monitoring (H.zea for pyrethroids and A. grandis for malathion). Entomology 

Science Conference. October 26- 28, 2005. College Station Conference Center. 

Invited presentation at the 61 ST Annual Meeting, North Central Branch, ESA. “Monitoring for 

pyrethroid resistance in Texas-2005. Suggestions for resistance monitoring and 

collaborative research.” Bloomington, IL, March 26-28, 2006. 

Invited presentation. “Validating GPCRs as targets for insecticides and acaricides”. Workshop 2 

- "Approaches for the identification of novel insecticide targets'. Fifth International 

Symposium in Molecular Insect Science. Tucson, AZ, May 20-25, 2006. 

Suresh D. Pillai 

Eavesdropping into microbial chatter: Institute of Food Technologists. Longhorn Chapter meeting. 

February, 2005 

Crop and pre-harvest threats to food security. American Society for Microbiology Conference on 

Biodefense Research. Baltimore, MD. March 2005. 

Invited Participant, American Society for Microbiology’s Biodefense Research Meeting, 

Baltimore, MD, March 2005. 

Eavesdropping on microbial chatter. IFSE- Texas Science Partnership. TAMU April 2005 

Eavesdropping on microbial chatter. Institute of Food Technologists annual Meetings, New 

Orleans, LA, July, 2005. 

Microbiology of Food Irradiation. Where do we go from here? Biotechnology Conference. Dallas, 

TX, August 2005. 

41


June 2006 

Molecular methods for microbial detection and characterization. DoD-DoE-EPA 

(SERDP/ESTCP) Molecular Biological Tools Workshop. Charlottesville, VA, Aug. 2005. 

Protecting humans from microbial pathogens. USEPA. Office of Water, Washington DC, August 

2005. 

Invited Participant, DoD-DoE-EPA Molecular Biological Tools Workshop, Charlottesville, VA, 

August 2005. 

Microbial detection methods: Can we move from fantasy to reality? USEPA – Pathogen 

Equivalency Committee Retreat, Hueston Woods, OH, September, 2005. 

Invited Participant, US EPA Pathogen Equivalency Committee Retreat, Hueston Woods, OH, 

September 2005. 

Invited Participant, WERF Directed Research Program Workshop, Washington DC, Nov. 2005. 

Invited Participant, USEPA Candidate Contaminant List Workshop, Washington DC, Dec. 2005. 

Garcia, N., J. Maxim and S.D. Pillai. Electronic pasteurization of cantaloupes to destroy viruses. 

TAMU Agriculture Program Conference. January 2006. *awarded 1 st prize for 

undergraduate student presentation 

Mittasch, S., M. Cepeda, K. Soni , J. Maxim and S.D. Pillai. Electron Beam Irradiation of 

Different Bacillus sp Spores in Aqueous Suspensions. TAMU Agriculture Program 

Conference. January 2006. *awarded 2nd t prize for undergraduate student presentation 

Microbial chatter to forward contamination: microbiology in the 21 st century. Poultry Science 

Department-USDA-ARS Seminar Series, Texas A&M University, February, 2006 

Invited Participant, USEPA Workshop on Large Sample Volume Concentration Methods, 

Cincinnati, OH. April 2006. 

Invited Participant, USEPA Candidate Contaminant List Workshop, Washington DC. June 2006. 

Weston W. Porter 

4th Era of Hope Meeting, Department of Defense (DOD) Breast Cancer Research Program 

(BCRP), Philadelphia, PA, June 8-11, 2005. 


Shashi K. Ramaiah 

Banerjee, A., Apte, U., and Ramaiah S. K. Evidence for osteopontin induction in vivo and in 

vitro: A possible mechanism for higher neutrophil transmigration and higher liver injury in 

female alcoholics. Society of Toxicology meeting, New Orleans, LA, March 2005. 

Banerjee, A. and Ramaiah S. K. Identification of ethanol responsive element in the rat 

osteopontin promoter. Texas Research Society on Alcoholism, College Station, 2005. 

Ramaiah, S. K., Banerjee, R., Pettway, R., and Jayaraman, A. Comprehensive gene profiling of 

the liver in a Lieber DeCarli Rat Model to predict progression to alcoholic steatohepatitis. 

Vet. Pathol. 42, 727, 2005. 

Cutting Edge Concepts in Liver Toxicologic Pathology; invited talk. Allergan Biopharmaceutical 

Company, Orange County, CA. 2005 

Banerjee A, RC Burghardt, GA Johnson, FJ White, SK Ramaiah. Temporal expression and 

localization of osteopontin mRNA and protein in the rat alcoholic steatohepatitis model. 

American College of Toxicology annual meeting, Williamsburg, VA, November 6-9, 2005. 

Frank M. Raushel 

Evolution of Substrate Specificity within Amidohydrolase Superfamily. ASBMB, Biology, San 

Diego CA, April 2, 2005. 

Amidotransferases: A Crooked Path from Substrates to Products. Department of Biological 

Chemistry, Johns Hopkins University. May 10, 2005. 

Amidohydrolase Superfamily: Mechanism, Design, and Discovery. Department of Biochemistry, 

Baylor College of Medicine, Houston, TX (April 21) 

The Mechanism of Uronate Isomerase. PacificChem 2005, Honolulu, Hawaii, Dec 20, 2005. 

42


June 2006 


TEFs: Biologic and Mechanistic Considerations. The Toxicology Forum, Washington, D.C. 

February 1-2, 2005. 

Mechanisms and Applications of Inhibitory Ah Receptor-ER Crosstalk in Breast Cancer. The 

Grand Rounds Seminar Series in the Barbara Ann Karamanos Cancer Institute, Detroit, MI. 

February 9-11, 2005. 

Nur77 Agonists as a New Class of Anticancer Drugs. The Pancreatic Cancer Group at the 

Barbara Ann Karamanos Cancer Institute, Detroit, MI. February 9-11, 2005. 

ERα/Sp1-Mediated Gene Expression in Breast Cancer. Baylor College of Medicine Breast 

Disease Research Group, Houston, TX. March 2, 2005. 

Regulation of Mammary Tumor Growth through the AhR. The Society of Toxicology Annual 

Meeting, New Orleans, LA. March 6-9, 2005. 

Mechanisms of Action on a New Class of PPARγ Agonists as Anticancer Drugs. The Boston 

University School of Medicine, Boston, MA. May 6, 2005. 

Endocrine Disruptors and Their Potential Impacts on Human Health. A meeting on "The 

Application of Systems Biology Methodologies to Environmental Research" at West Virginia 

University, Morgantown, VA. August 1-3, 2005. 



Senseman, S.A. Mind mapping: An innovative tool for effective teaching, writing, and 

managing. Oklahoma State University, Plant and Soil Sciences, Stillwater, OK, 2005. 

Hoffman, D.W., S.A. Senseman, M.C. Dozier, and J.E. Wolfe. Hydrologic measurement of 

stormwater runoff from Texas croplands. Weed Sci. Soc. Am. Abstr. 50:73. 2005. 

Dozier, M.C., P.A. Baumann, S.A. Senseman, J. Bragg, and A. Spencer. Integrated 

management strategy for the implementation of BMPs for an atrazine TMDL for Aquilla 

Reservoir. Weed Sci. Soc. Am. Abstr. 50:88. 2005. 

Senseman, S.A. My professorial experience so far: Reflections from a reluctant academic. 

Weed Sci. Soc. Am. Abstr. 50:91. 2005. 

Avila, L.A., J.H. Massey, S.A. Senseman, S.R. Lancaster, G.N. McCauley, and J.M. Chandler. 

Imazethapyr photodegradation in rice paddy water. Weed Sci. Soc. Am. Abstr. 50:99. 2005. 

Vencill, W.K., E.P. Prostko, and S.A. Senseman. Effect of soil pH on bioavailability of imazapic. 

Proc. South. Weed Sci. Soc. 58:000. 2005. 

Steele, G.L., S.A. Senseman, and J.M. Chandler. Diuron effects on absorption and 

translocation of glyphosate in sharppod morningglory (Ipomoea cardatotriloba). Proc. 

South. Weed Sci. Soc. 58:000. 2005. 

Dozier, M.C., P. Baumann, S.A. Senseman, J. Bragg, and A. Spencer. Integrated management 

strategy for the development and implementation of an atrazine TMDL for Aquilla Lake. 

Proc. South. Weed Sci. Soc. 58:000. 2005. 

Lancaster, S.R., M.C. Dozier, K.H. Carson, and S.A. Senseman. Pesticide monitoring in the 

Aquilla watershed. Proc. South. Weed Sci. Soc. 58:000. 2005. 

Matocha, M.A. and S.A. Senseman. Halosulfuron dissipation at selected pH values in spray 

tank water. Proc. South. Weed Sci. Soc. 58:000. 2005. 

Avila, L.A., J.H. Massey, S.A. Senseman, S.R. Lancaster, G.N. McCauley, and J.M. Chandler. 

Imazethapyr photodegradation in rice paddy water. Proc. South. Weed Sci. Soc. 58:000. 

2005. 

Avila, L.A., J.H. Massey, S.A. Senseman, K.L. Armbrust, S.R. Lancaster, G.N. McCauley, and 

J.M. Chandler. Imazethapyr photodegradation in rice paddy water. Abst. Papers Amer. 

Chem. Soc. 229:U69-U69 013 AGRO. 2005. 

43


June 2006 

Lancaster, S.R., S.A. Senseman, R.L. Haney, F.M. Hons, and J.M. Chandler. Effects of cotton 

pesticide programs on soil microbial activity. Texas Plant Prot. Assoc. Conf. Proc. 2005. 

Third place poster presentation 

Matocha, M.A., L.J. Krutz, S.A. Senseman, C.H. Koger, and K.N. Reddy. Spray carrier pH effect 

on absorption and translocation of trifloxysulfuron in Palmer amaranth (Amaranthus palmeri) 

and Texasweed (Caperonia palustris). Texas Plant Prot. Assoc. Conf. Proc. 2005. First 

place poster presentation 

Lancaster, S.R., S.A. Senseman, R.L. Haney, F.M. Hons, and J.M. Chandler. Effects of 

pesticide programs for cotton on soil microbial activity. Proc. South. Weed Sci. Soc. 59:000. 

2006. First place poster presentation 

Dozier, M.C., P.A. Baumann, S.A. Senseman, T. Gerik, and W. Harman. Atrazine losses in two 

tillage systems. Proc. South. Weed Sci. Soc. 59:000. 2006. 

Matocha, M.A., L.J. Krutz, S.A. Senseman, K.N. Reddy, M.A. Locke, and R.W. Steinried, Jr. 

Foliar washoff potential and surface runoff losses of trifloxysulfuron in cotton (Gossypium 

hirsutum). Proc. South. Weed Sci. Soc. 59:000. 2006. 

Matocha, M.A., L.J. Krutz, S.A. Senseman, K.N. Reddy, and C.H. Koger. Influence of spray 

water pH on absorption and translocation of trifloxysulfuron in Palmer amaranth 

(Amaranthus palmeri) and Texasweed (Caperonia palustris). Proc. South. Weed Sci. Soc. 

59:000. 2006. Second place oral presentation 

Mersie, W., M.B. Riley, J.A. Dumas, E.E. Gbur, J.H. Massey, J.D. Mattice, T.C. Mueller, T. 

Potter, S.A. Senseman, and E. Watson. Pesticide extraction efficiency of two solid phase 

disk types after shipping. Weed Sci. Soc. Am. Abstr. 51:000. 2006. 


“Comparative biology as a key to understanding uterine development and function.” Young 

Investigator Award Lecture, Annual Meeting of the Sigma Xi Society, Seattle, Washington. 

November, 2005. 

“Endogenous retroviruses in the female reproductive tract: potential roles in placental 

morphogenesis and mucosal immunity”. Annual Meeting of the American Society for 

Reproductive Immunology, Nashville, Tennessee. June, 2006. 

“Developmental biology and functional role of endometrial glands in the uterus”. Gordon 

Research Conference on Reproductive Tract Biology, New London, Connecticut. June, 

2006. 


ASA invited Chance Lecturer, 2005 

Bullet Lead Lecture at Clarkson University, Potsdam, NY, 2005 

Bullet Lead Lecture at Washington Statistical Society, 2005 

Bullet Lead Lecture at University of Southern California, Los Angeles, CA, 2005 

John N. Stallone 

Experimental Biology '06, San Francisco, CA, 2006 

Evelyn Tiffany-Castiglioni 

Concepts of In Vitro Neurotoxicology: Applications to Drug Discovery,@ Invited speaker for 5 th 

International Conference on Early Toxicity Screening: Strategies and Approaches for 

Toxicity Screening in Drug Discovery and Development, Jean Harry, session chair, San 

Diego, CA, February 21-23, 2005. 

In Vitro Models for Testing Neurotoxicity of Organophosphorus Compounds and Protective 

Effects of OP Hydrolase,@ Invited speaker for Symposium on ANeurotoxicity of 

Organophosphates & Carbamates,@ Ramesh Gupta, chair, Society of Toxicology 43 nd 

Annual Meeting, New Orleans, LA, March 20-25, 2005. 

44


June 2006 

In Vitro Systems and Developmental Neurotoxicity,@ Plenary speaker for TestSmart 

Developmental Neurotoxicity Testing meeting, sponsored by Center for Alternatives to 

Animal Testing (CAAT), Johns Hopkins University, NIH, and EPA, Washington, DC, March 

13-15, 2006. 

In Vitro Models of Neural Responses to Lead (Pb),@ Invited speaker for Symposium on A New 

Concepts in the Neurotoxicology of Lead,@ Lori White, chair, Society of Toxicology 44 th 

Annual Meeting, San Diego, CA, March 5-9, 2006. 

Nancy D. Turner 

Experimental Biology ’06, San Francisco, CA, 2006. 

Naisyin Wang 

Sonia Kovalevsky Mathematics Day lecture, Mississippi State University, MS 

Mathematics Department, Mississippi State University, MS 

Biostatistics Department, University of Washington, Seattle, WA 

Biostatistics Department, University of Rochester, Rochester, NY 

International Chinese Statistical Association’s Applied Statistics Symposium, Washington, DC, 

June 2005 

Department of Mathematics, Mississippi State University, MS 

NSF Focused Research Group Conference ``Nonparametric Models for Complex Biological 

Data'', UC Davis, Davis, CA, August 2005. 

Department of Statistics, Oregon State University, Corvallis, OR 

Biostatistics Department, Harvard School of Public Health, Boston, MA, March 2006. 

Emily Wilson 

Houston Area Muscular Dystrophy Association, Vascular Remodeling in Mouse Models of 

Muscular Dystrophies, Houston, TX 

International Presentations 


Joyce MM, RD Geisert, RC Burghardt, GA Johnson. Stat 1 is differentially regulated by 

conceptus estrogen and proteins in the porcine uterus. 38 th Annual Meeting of the Society 

for the Study of Reproduction, Québec, Canada, July 24-27, 2005 

White FJ, RC Burghardt, BA Croy, GA Johnson. Osteopontin is expressed by endometrial 

macrophages and decidual natural killer cells during mouse pregnancy. 38 th Annual Meeting 

of the Society for the Study of Reproduction, Québec, Canada, July 24-27, 2005 

Johnson GA, FJ White, JW Ross, MM Joyce, RD Geisert, RC Burghardt. Steroid regulation of 

cell specific ostopontin expression in the pregnant porcine uterus. 38 th Annual Meeting of 

the Society for the Study of Reproduction, Québec, Canada, July 24-27, 2005 

Burghardt RC, FJ White, SJ Gregg, MMJoyce, TE Spencer, GA Johnson. The induction of 

osteopointin in ovine endometrial stroma requires conceptus attachment. 38 th Annual 

Meeting of the Society for the Study of Reproduction, Québec, Canada, July 24-27, 2005 


Invited talk entitled “Docosahexaenoic acid: an important membrane-altering omega-e fatty 

acid” at the Omega-3 Fatty Acids: From Bench to Bedside Symposium, University of 

Guelph, Guelph, Ontario, Canada, October 21, 2005. 


Children’s Environmental Health in Central Asia Conference, Almaty, Kazakhstan. April 2005. 

45


June 2006 

Peking Health Science Center, China. Nov. 2005. 

Health Canada’s Environmental & Occupational Toxicology Seminar, Ottawa, Canada. Mar. 22, 

2006 

Conference on Current and Future Challenges in Environmental Health, Toxicology and Food 

Safety in Eastern and Central Europe, Kiev, Ukraine. May 2006. 


National Dong Hua University, Hualein, Taiwan, March 10, 2006, Nanostructure Symposium, 

“New Chemistry with an Old Element - Gold with Nitrogen Ligands for Catalysis” 

Tamkang University, March 13, 2006, “New Chemistry with and Old Element - Gold with 

Nitrogen Ligands” 

National Tsing Hwa University , Hinschu, Taiwan- “New Chemistry with and Old Element - Gold 

with Nitrogen Ligands” 

Quimica Organometalica, Universidad de Murcias. Murcia, Spain May 10, 2005, “Gold, an Old 

Element with a New Chemistry”. 

Quimica Inorganic, Universidad de Zaragoza, Zaragoza, Spain, May 12, 2005, “Gold, an Old 


Quimica Inorganic, Universidad de La Rioja, Logrona, Spain, May 16, 2005, “Gold, an Old 


Universitá di Milano, Italy, “Gold, an Old Element with a New Chemistry”, May 2005 

Universitá di Camerino, Italy “Catalysis with Gold and Green Chemistry”, May 2005 

Roger B. Harvey 

Australasian Pig Science Assoc. 10th Biennial Conference, Christchurch, New Zealand, Nov. 

2005. 


Invited Speaker, Mycoglobe Conference, Ghana, West Africa, 2005 

Invited Speaker, World Mycotoxin Forum, European Commission, Amsterdam, 2005 

Expert Panel on Aflatoxins, CDC/WHO, Geneva, Switzerland, 2005 


Nachman, R.J., M. Adams, Jan 9-13 2005, F. Etzkorn, J. Zabroki, K. Kaczmarek and G. Coast. 

Structural and conformational aspects of the interaction of insect kinins and pyrokinin-like 

neuropeptides with expressed receptors. Invertebrate Neuropeptide Conference. Chiang 

Mai, Thailand, Jan 9-13 2005. 

Invited presentation. Pietrantonio, P.V., C. Jagge and S. Taneja-Bageshwar. “G protein-coupled 

receptors from mosquitoe Aedes aegypti (L.) excretory system: characterization, function 

and structure-activity relationships.” Workshop: “Molecular and population biology of 

mosquitoes.” Kolymbari, Crete, Greece, 2005. 

Nachman, R.J., Williams, H., Taneja-Bageshwar, S., Y.J. Kim, P. Zubrzak, G. M. Coast, A. 

Strey, M. Adams, J. Zabrocki, R.E. Isaac, P.V. Pietrantonio. Interaction of analogs of insect 

neuropeptides with expressed receptors. IV- International conference on arthropods: 

chemical, physiological and environmental aspects. Zakopane, Poland, Sept. 19-23, 2005. 

Pietrantonio, P.V., S. Taneja-Bageshwar ♦ , A. Strey, and R.J. Nachman. “Comparative structureactivity 

analysis of insect kinin core analogs on recombinant kinin receptors from Southern 

cattle tick Boophilus microplus (Acari: Ixodidae) and mosquito Aedes aegypti (Diptera: 

Culicidae).” IV- International conference on arthropods: chemical, physiological and 

environmental aspects. Zakopane, Poland, Sept. 19-23, 2005. 

Nachman, R. J., S. Taneja- Bageshwar, A. Strey, P. Zubrzak, R. Elwyn Isaac, G. M. Coast and 

P. V. Pietrantonio. Interaction of biostable, beta-amino acid insect kinin analogs with 

46


June 2006 

expressed receptors -- B. Exploring the functional role of a salt bridge in sulfakinins with 

restricted conformation analogs. Guanajuato, Mexico. February 2006. 


Food safety and environmental biotechnology opportunities. Tecnologico de Monterrey, (ITESM), 

Mexico City, Mexico, March 2005. 

Ultrasonic technology for waste water disinfection. Texas A&M University-Conacyt Research 

Symposium. Mexico City, Mexico. October, 2005. 

Food safety and food irradiation: global necessities for the 21 st century. Bhabha Atomic Research 

Center, Mumbai, India. February 2006. 

Food safety and food irradiation: global necessities for the 21 st century. Kerala Agricultural 

University, Thrissur, Kerala, India, February 2006. 

Member, International Organizing Committee, 2 nd International Congress on Bioprocessing in 

Food Industries, Patras, Greece. June 2006. 


Gordon Research Conference, Mammary Gland Biology, Barga, Italy, May 28-June 2, 2006. 


Proteomic Applications in clinical diagnosis. Invited presentation at the Annual meeting of the 

International Society for Clinical Biochemistry of Domestic Animals, Istanbul, Turkey, April 

18, 2006. 

On differential diagnosis of liver disease. Invited CE presentation at the Annual meeting of the 

International Society for Clinical Biochemistry of Domestic Animals, Istanbul, Turkey, April 

18, 2006. 


Enzyme Library for the Kinetic Resolution of Chiral Phosphates, Phosphonates, and 

Phosphinate Esters. German Priority Program, Regensburg, Germany, March 7, 2005 

Diversity in the Structure and Mechanism of the Amidohydrolase Superfamily. Canadian 

Chemistry Conference, Halifax, Canada, May 30, 2006. 

Evolution and Mechanism of the Amidotransferase Family of Enzymes. Trends in Enzymology, 

Lake Como, Italy, June, 10, 2006. 


Mechanisms of AhR-ERα Crosstalk in Breast Cancer Cells. The Institute for Risk Assessment 

Sciences, College of Veterinary Medicine, University of Utrecht, The Netherlands, January 

2005. 

Toxic Equivalency Factors for Dioxin and Related Compounds. World Health Organizationsponsored 

review, Geneva, Switzerland, June 2005. 

Critical Advances in the Toxicology of Dioxin and Related Compounds. Plenary Lecture at the 

Dioxin 2005 annual meeting. Toronto, Canada, August 2005. 

Signaling Pathways Resulting from Ligand-Dependent Activation of Orphan Receptors. As part 

of a Texas - United Kingdom Collaborative Research Initiative workshop on "Post-Receptor 

Events in Cell Signaling and Disease". University of Dundee, Scotland, Sept. 2005. 

The Ah Receptor as a Drug Target - Selective Ah Receptor Modulators (SAhRMs). A 

symposium focused on the "Ah Receptor." Dusseldorf, Germany. Sept. 2005. 


Senseman, S.A., J.H. Massey, M.C. Dozier, and G.N. McCauley. Environmental Issues in 

United States Rice Production. IV Congresso Brasileiro de Arroz Irrigado/XXVI Reuniao da 

Cultura do Arroz Irrigado, Santa Maria, RS, Brazil. 2005. 

47


June 2006 

Mind mapping and group writing/editing: A couple of ideas for reducing the pain of writing. 

Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. September 

2005. 

Mind mapping and group writing/editing: A couple of ideas for reducing the pain of writing. 

Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. November 

2005. 

Haney, R.L., L.J. Krutz, and S.A. Senseman. Microbial activity and atrazine degradation from 

mixtures of glyphosate and atrazine. Universidade Federal de Rio Grande do Sul, Porto 

Alegre, RS, Brazil, 2005. 

Avila, L.A., S.A. Senseman, J.L. Ullman, D.J. Lee, G.N. McCauley, J.M. Chandler, and L.J. 

Krutz. Efeito da umidade do solo na corcao e disponibilidade de imazetapir em tres solos. 

Anais IV Congresso Brasileiro de Arroz Irrigado/Irrigado/XXVI Reuniao da Cultura do Arroz 

Irrigado, Santa Maria, RS, Brazil, 2005. 

Inivited presentation. Mind mapping and group writing/editing: A couple of ideas for reducing 

the pain of writing. EPAGRI, Santa Catarina, Brazil. January 2006. 


“Progesterone regulation of uterine function and conceptus growth: genes and conundrums”. 

University of Nottingham, Sutton Bonington Campus, England. April, 2005. 

“Endogenous betaretroviruses in sheep: biological roles in uterine function, conceptus growth, 

and placental differentiation”. Institute of Comparative Medicine, University of Glasgow 

Veterinary School, Glasgow, Scotland. April, 2005. 

“Programming of neonatal and adult uterine development and function by hormones: impacts 

on conceptus survival and development”. New Investigator Exchange Lecturer, Fertility 

2005, Warwick University, Conventry, England. April, 2005. 

“Endogenous betaretroviruses of sheep: biological roles in uterine function and placental 

morphogenesis”. Mini-Symposium X. Endogenous Retroviruses and Reproduction, Annual 

Meeting of the Society for the Study of Reproduction, Quebec City, Canada. July, 2005. 

“Induction of osteopointin in ovine endometrial stroma requires conceptus attachment.” 38 th 

Annual Meeting of the Society for the Study of Reproduction, Québec, Canada, July, 2005. 

“Progesterone regulation of peri-implantation conceptus development: genes and conundrums”. 

Havemeyer Foundation Workshop on Embryonic and Fetal Nutrition, Ravello, Italy. May, 

2006. 


“In Vitro Models for Testing Neurotoxicity of Organophosphorus Compounds,” invited speaker 

and chair for Symposium on “In Vitro Models and Biosensors for Detecting Neurotoxicity,” 

10 th Meeting of the International Neurotoxicology Association, Porvoo, Finland, June 26-July 

1, 2005. 

“Metal Accumulation by Astrocytes: Relationship to Disease,” Invited speaker and chair for 

Colloquium on “Astrocytes in Neurodegenerative Disease Processes,” International Society 

for Neurochemistry-European Society for Neurochemistry Congress, Innsbruck, Austria, 

August 21-26, 2005. 

“Metal Accumulation by Astrocytes: Relationship to Disease,” College of Veterinary Medicine, 

University of Cambridge, July 5, 2005. 

“Metal Accumulation by Astrocytes: Relationship to Disease” Wolfson Centre for Age-Related 

Diseases, King’s College, London. July 4, 2005. 

Naisyin Wang 

Conferernece of International Statistics Institutes, Sydney, Australia, April 2005. 

National Taiwan University, Taiwan, 2005. 

Academia Sinica, Taiwan, 2005. 

48


June 2006 

APPENDIX H – Service Activities 

I. Departmental, College and University Service 

A. Department Level 


Faculty Supervisor, Veterinary Biosciences Histology Service Laboratory, 1999 – 

present 


Chair, Promotion and Tenure Committee, Dept. of Veterinary Biosciences 


Head, Dept. of Environmental & Occupational Health, SRPH, TAMHSC, 2002- 

present 


Awards Committee, Dept. of Chemistry 


Search Committee, Charles Parencia Chair in Cotton Entomology, Dept. of 

Entomology, 2005-present 

Graduate Recruitment and Admissions Committee, Dept. of Entomology, 2004-2007 


Scholarship and Awards Committee, Dept. of Veterinary Pathobiology 

Search Committee, Toxicology faculty recruitment, Dept. of Veterinary Physiology & 

Pharmacology, 2004-present 


Chair, Search Committee, Toxicology faculty recruitment, Dept. of Veterinary 

Physiology & Pharmacology, 2000-present 


Chair, Search Committee, Turf Ecology position, Dept. of Soil & Crop Sciences, 2005 

Eric E. Simanek 

Chair, Organic Division, Dept. of Chemistry, 2004-2005 

Director of the First Year Program, Dept. of Chemistry 

Chair, Mass Spec Users Group, Dept. of Chemistry 

Graduate Admissions Committee, Dept. of Chemistry 


Research Advisory Committee, Dept. of Animal Science, 2005-present 

Faculty Coordinator: Physiology Field Laboratory, Veterinary Medical Park Swine 

Facility, and Nutrition Physiology Center, Dept. of Animal Science, 2001-present 

James A. Thompson 

Graduate Advisor, Dept. of Large Animal Medicine & Surgery 


Head, Veterinary Integrative Biosciences 


Search Committee, Molecular/Cellular Nutrition position, Dept. of Nutrition & Food 

Science 

Awards Committee, Dept. of Nutrition & Food Science 

Naisyin Wang 

Chair, Graduate Program Committee, Dept. of Statistics 

Faculty Recruiting Committee, Dept. of Statistics 

Chair, Biostatistics Prelim Examination Committee, Dept. of Statistics 

49


June 2006 

James R. Wild 

Undergraduate Program Committee, Dept. of Biochemistry & Biophysics 

Emily Wilson 

Director of Cell Culture Facilities, Dept. of Systems Biology & Translational Medicine 

Faculty Search Committee, Dept. of Veterinary Physiology & Pharmacology 

Faculty Search Committee, Dept. of Health & Kinesiology 

B. College Level 


Chair, supervisory committee, Plum Endowed Scholarship in Veterinary Medicine, 

2005-present, CVM 


Member, Promotion and Tenure Committee, CVM 

Director, Image Analysis Laboratory, CVM 


Executive Committee, CVM, 2004-present 


Admissions Committee, TAMHSC College of Medicine, 2003-present 


Selection Committee, TAMUS Vice Chancellor Awards in Excellence, 2004-2007 

Chair, COALS selection committee for Phi Kappa Phi Outstanding Junior, 2005 


Scholarship and Awards Committee, CVM 

Search Committee, Assoc. Dean for Research and Graduate Studies, CVM 


Gamma Sigma Delta Honorary Agricultural Fraternity: Member, Historian 2002, 

Secretary 2003, Vice President 2004, Vice President 2005, President 2006 


Executive Committee, CVM 

Chair, Biomedical Science Executive Committee, CVM 

James R. Wild 

IDC Chairman Committee, COALS 

Emily Wilson 

Faculty Affairs Committee, College of Medicine, TAMHSC 

Departmental Realignment Committee, College of Medicine, TAMHSC 

Guest Interview for Medical Admissions, College of Medicine, TAMHSC 

Graduate Admissions Committee Chair, College of Medicine, TAMHSC 

Graduate Instruction Committee, College of Medicine, TAMHSC 

C. University Level (includes interdisciplinary service) 


Member, Curriculum committee, Faculty of Neuroscience, TAMU, 1998-2005 

Chair, Curriculum committee, Faculty of Neuroscience, TAMU, 2004-present 

A. Catherine Barr 

Diagnostic Veterinary Toxicology Service, TVMDL, 1991-present 


Chair, Faculty of Toxicology, 2005-present 


Chair, Faculty of Nutrition, Texas A&M University, 2002-2005 


Director, Analytical Core, Center for Environmental & Rural Health, 1998-present 

50


June 2006 


Faculty Senate, 2003 Executive Committee 

University Distinguished Professors Executive Committee 

Quality Enhancement Plan Council, Chair 


Life Sciences Building Scientific Advisory Committee 

Interdisciplinary Faculty of Toxicology, Executive Committee Member, 2005-present 


Executive Committee, Interdisciplinary Faculty of Toxicology, 2002-2005 


Steering Committee, Center for Food Safety, 1994-present 

System Committee on Infectious Biohazards, 2002-present 

Executive Committee, Interdisciplinary Faculty of Toxicology, TAMU, 1990-present 

Executive Committee, Interdisciplinary Faculty of Food Science, TAMU 

Chair, Interdisciplinary Faculty of Toxicology, 2001-2005 

Director, Center for Food Safety, TAMU, 2001-2005 


Ford Foundation research project on “Diversification and the Academy,” 2005 

Women Faculty Network, 1996- present 





John C. Reagor 

Veterinary Diagnostic Services, TVMDL, 1971-present 


Executive Committee, Interdisciplinary Faculty of Toxicology, TAMU, 1990-present 


Center for Animal Biotechnology and Genomics, 1997-present 

Center for Environmental and Rural Health, Scientific Advisory Group, 2005-present 

Faculty of Biotechnology, 2001-present 

Faculty of Genetics, 2002-present 

Chair, Faculty of Reproductive Biology, 2004-2006 

Chair, Institutional Agricultural Animal Care and Use Committee, 2004-2006 

Texas A&M Women’s Studies Program, 2002-present 


University Laboratory Animal Care Committee 

TAMU Faculty Senate 


Graduate Instruction Council 

Yanan Tian 

Executive Committee, Interdisciplinary Faculty of Toxicology, 2002-present 


Search Committee, Dept. Head of Neuroscience & Experimental Therapeutics 

(TAMHSC) 


Chair of the Intercollegiate Faculty of Nutrition, 2005-present 

James R. Wild 

Chair, Faculty of Genetics, 2005-present 

Scientific Leader, DREAMS R&D Collaboration 

Emily Wilson 

51


June 2006 

Pilot Project Committee, Center for Environmental & Rural Health 

TAMU Women’s Faculty Network 

Graduate Program Council, TAMHSC 

Member, Transgenic Mouse Core Facility Advisory Board, TAMUS 

II. National and International Organizations 


American Association of Veterinary Anatomists, President, 2004-2005 

American Veterinary Medical Association 

Cajal Club 

Fulbright Association 

Neurotoxicity Society 

Phi Beta Kappa 

Phi Zeta 

Sigma Xi 

Society for Neuroscience 

Society for Neuroscience - TAMU Chapter 

Society of Toxicology 

Neurotoxicology Specialty Section, Nom. Committee Member, 2005 


American Academy of Veterinary and Comparative Toxicology 

American Association for Veterinary Laboratory Diagnosticians 


Society for the Study of Reproduction, Member (SSR), 1984-present 

Chair, Awards Committee, SSR, 2004-2005. 

Co-Chair, Publications Committee, SSR, 2005-2006. 

Society of Toxicology, 1999-present 


American Association for Cancer Research, 1993-Present 

American Society for Cell Biology, 2004-Present 

American Society for Nutritional Sciences, 1989-Present 

Federation of American Societies for Experimental Biology, 1989-Present 

Sigma Xi, 1991-Present 


American Association for the Advancement of Science 

American Chemical Society 

American Crystallographic Association 

American Institute of Chemists (Fellow) 

American Men and Women in Science 

Board of Editors, J. Cluster Science 

New York Academy of Science 

Pegasus Society Robinson College, Cambridge 

Sigma Xi 

Texas Academy of Science, Director 1987-90. 

Texas Alliance for Mathematics and Science Education 

The Royal Society of Chemistry 

Valparaiso University, Chemistry Advisory Committee 

Who’s Who in America 

Gladys Y.L. Ko 

Association for Research in Vision and Ophthalmology 


52


June 2006 




Teratology Society 


American Physiological Society 

American Society of Nephrology 

American Society for Pharmacology and Experimental Therapeutics. 


American Council on Science & Health, Board of Scientific Advisors 

Research Advisor - Thrasher Research Fund, Salt Lake City, UT 

Scientific Advisory Board, Ralston Purina International, St. Louis, MO 

World Health Organization/FAO Advisory Council on Mycotoxins 

UNICEF: Mycotoxin analysis of moldy grain from Africa. 


Entomological Society of America, 1991-present 

American Chemical Society, 1996-present 

Society for Vector Ecology, 2003-present 

Sigma Xi Honor Society 

Gamma Sigma Delta, Honor Society of Agriculture 


International Association of Food Protection (IAFP) Committee on Fruits and Vegetables 

Chair, 2005-2006 


American Association for Cancer Research 



American Association for Investigative Pathology 

American Association for the Study of Liver Diseases 

American College of Toxicology 

American College of Veterinary Pathologists 

American Society for Veterinary Clinical Pathology 

American Veterinary Medical Association 

Gulf Coast Chapter of the Society of Toxicology 

Secretary, 2006 

Society of Toxicologic Pathology 

Co-Chair, Continuing Eduction Committee 

Member, Public Relations Committee 


Texas Research Society on Alcoholism 

John C. Reagor 

American Association of Veterinary Laboratory Diagnosticians 

United States Animal Health Commission 




American College of Toxicology 

American Society for Mass Spectrometry 

Avax Technologies, Scientific Advisory Board, 1998-present 

Canadian Centre for Toxicology-Steering Committee, 1979-present 

Canadian Federation of Biological Societies 

53


June 2006 

Canadian Society for Toxicology 

Chemical Institute of Canada 

Consultant, Science Advisory Board of E.P.A., 1984-present 

Dioxin Symposia, International Advisory Board, 1980-present 

External Adv. Board, Environmental Health Center, University of Texas, 1995-present 

International Society for the Study of Xenobiotics 

National Toxicology Program, Advisory Committee (SACATM), 2004-present 

NIEHS Scientific Adv. Committee, Alt. Toxicological Testing Methods, 2002-present 

Ontario Ministry of the Environment - Dioxin Advisory Group, 1983-present 

Plantacor, Scientific Advisory Board, 2004-present 

Sigma Xi 


Awards Committee, 2003-present 

The Chemical Society 



American Society of Agronomy 

Gamma Sigma Delta 

Sigma Xi 

Southern Weed Science Society 

Texas Plant Protection Association 

Weed Science Society of America 



American Society of Animal Science 

Endocrine Society 

Gordon Research Conference on Reproductive Tract Biology, Vice Chair-2006, Chair- 

2008 

Sigma Xi 

Society for the Study of Reproduction 

Public Affairs Committee-FASEB Science Policy Committee Representative, 2003- 

2005 

Society for the Study of Reproduction and Fertility 

Texas Women’s Reproductive Health Consortium 

Steering Committee, 2003-2005 

Organizer, Texas Forum on Reproductive Sciences, 2006 



American Statistical Association 

Bernoulli Society 

Institute of Mathematical Statistics 

International Environmetrics Society 

International Statistical Institute 

Proteomics Program at the National Cancer Institute, Consultant 

Society for Applied Spectroscopy 



Microcirculatory Society 


American College of Preventive Veterinary Medicine 

American College of Theriogenology 

54


June 2006 

American Statistical Association (Bayesian Chapter) 

Society for Theriogenology 


American Association for the Advancement of Science, 1980-present 

American Association of Veterinary Anatomists, 1987 - present 

American Society for Neurochemistry, 1982-present 

International Neurotoxicology Conference, 

Program Committee Member, Research Triangle Park, NC, 2005 

Program Committee, Little Rock, AK, 2006 

National Institute of Occupational Safety and Health SOH Study Section (2003-present) 

NSF Graduate Fellowships Review Panel 2005 

Society for Neuroscience, 1989-present 

Society of Toxicology, 1997-present 



American Association of Cereal Chemists 


American Society for Nutritional Sciences 

Jury Member, Excellence in Nutrition Education Award, October 2005 

Chair, Postdoctoral Proposal Review Committee, February 2006 

American Society for the Advancement of Science 

American Society of Animal Science 

Gamma Sigma Delta 

Sigma XI 

Society for Experimental Biology and Medicine 

The New York Academy of Sciences 

Women's Faculty Network 

Naisyin Wang 

American Statistical Association 

Institute of Mathematical Statistics 

International Biometrics Society 

International Chinese Statistics Association 

International Statistics Institutes 

NIH BMRD study section, 2004-2008 

James R. Wild 


International Union of Pure and Applied Chemistry 

NATO Chem/Bio Working Group PG-31 

Cody L. Wilson 

Society for Risk Analysis 


Emily Wilson 


American Heart Association-Basic Science - Hypertension 

American Society of Biochemistry and Molecular Biology 

American Society of Cell Biology 

Microcirculation Society 

III. Editorial Work 

A. Ad hoc Review 


55


June 2006 

American Journal of Veterinary Research 

Brain Research 

In Vitro Toxicology 

International Journal of Developmental Neuroscience 

Neuroscience 

Neurotoxicity Research 

Toxicology Letters 


Journal of Veterinary Diagnostic Investigation 


Biology of Reproduction 

Biochemical Pharmacology 

Cells, Tissues, Organs 

European Journal of Obstetrics & Gynecology and Reproductive Biology 

NeuroToxicology 

Reproduction 

Reproductive Biology and Endocrinology 

Toxicological Sciences 


American Journal of Pathology 

Reproductive Toxicology 


American Journal of Physiology: Renal Physiology 

Biochemical Pharmacology 

British Journal of Pharmacology 

Cell Biology and Toxicology 

Environmental Health Perspectives: Toxicogenomics 

In Vitro Cellular and Developmental Biology 

International Journal of Pharmaceutics 

Journal of Molecular Histology 

Journal of Ocular Pharmacology and Therapeutics 

Journal of Pharmacology and Experimental Therapeutics 

Journal of Vascular Research 

Life Sciences 

Mechanisms of Ageing and Development 


Toxicology and Applied Pharmacology 

Toxicology In Vitro 



Archives of Environmental Contamination and Toxicology 

Food Additives & Contaminants 

Journal of Agriculture and Food Chemistry 

Journal of Pharmacology and Experimental Therapeutics 

Journal of the Association of Official Analytical Chemists 

Journal of Toxicological Sciences 

Journal of Toxicology and Applied Pharmacology 

Journal of Toxicology and Environmental Health 


American Journal of Veterinary Research 

Hepatology 

56


June 2006 

International Journal of Toxicology 

Journal of American Veterinary Medical Association 

Journal of Pathology 


Veterinary Clinical Pathology 


Cancer Research 


Chemosphere 

Clinical Cancer Research 

Endocrinology 

Journal of Biological Chemistry 

Journal of Cellular Biochemistry 

Journal of Molecular Biology 

Journal of Molecular Endocrinology 

Molecular and Cellular Endocrinology 

Molecular Cancer Therapeutics 

Molecular Endocrinology 

Molecular Genetics and Metabolism 

Molecular Medicine 

Molecular Pharmacology 

Nature Medicine 

Science 



Environmental Science & Technology 

Journal of Agricultural and Food Chemistry 

Journal of Cotton Production 

Weed Science 

Weed Technology 


American Zoologist 

Anatomical Record 


BMC Reproductive Biology and Endocrinology 

BMC Genetics 

Canadian Journal of Physiology and Pharmacology 

Domestic Animal Endocrinology 

Endocrine 

Endocrinology 

Experimental Cell Research 

In Vitro Cellular and Developmental Biology-Animal 

Journal of Anatomy 

Journal of Animal Science 

Journal of Biological Chemistry 

Journal of Clinical Endocrinology and Metabolism 

Journal of Endocrinology 

Journal of Molecular Endocrinology 

The Journal of Nutrition 

Molecular Endocrinology 

Preclinica 

57


June 2006 

Reproduction 

Reproduction, Fertility and Development 


British Journal of Pharmacology 

Critical Care Medicine 

Hypertension 

Journal of Pharmacology Experimental Therapy 



Journal of Neuroscience Methods 


Neurotoxicology 



American Journal of Clinical Nutrition 

Biochimica et Biophysica Acta 

Cancer Letters 

Cereals Food World 

European Journal of Clinical Nutrition 

Journal of Nutrition 

Nutrition and Cancer 

Emily Wilson 

Biomechanics and Modeling in Mechanobiology 

Cardiovascular Research 

Hypertension 

Journal of Vascular Biology 


B. Editorial Board Member 


Cells, Tissues, Organs 


Prostaglandins, Leukotrienes and Essential Fatty Acids 

Chemistry and Physics of Lipids 


Journal of Cluster Science 




Cell Biology and Toxicology 



Food Additives & Contaminants 


Archives of Insect Biochemistry and Physiology 


Journal of Food Protection 


International Journal of Toxicology 

Veterinary Clinical Pathology 


58


June 2006 

Archives of Biochemistry and Biophysics 

Biochemistry 

Bioorganic Chemistry 


European Journal of Pharmacology 

Handbook of Environmental Chemistry 

Journal of Biochemical and Molecular Toxicology 


Journal of Women's Cancer 

Toxicological and Environmental Chemistry 


American Journal of Reproductive Immunology 


BMC Reproductive Biology and Endocrinology 

Domestic Animal Endocrinology 

Reproduction 


Journal of Environmetrics 

Journal of Proteome Research 

Journal of Transportation and Statistics 


American Journal of Physiology 

American Journal Veterinary Research 



Naisyin Wang 

Biometrics 

C. Editor or Associate Editor 


Associate Editor, American Society for Nutritional Sciences Newsletter 


Editor, Comments on Inorganic Chemistry 

Editor, Profiles in Inorganic Chemistry 


Editor, Birth Defects Research: Clinical and Molecular Teratology 


Co-Editor, Food Additives & Contaminants 


Associate Editor, Environmental Entomology 


Toxicology Editor, Chemosphere 

Co-editor, Environmental Toxin Series 

Associate Editor, Toxicological Sciences 


Associate Editor, Agronomy Journal 


Associate Editor, Biology of Reproduction 


Editor, Chemometrics and Intelligent Laboratory Systems 


59


June 2006 

Associate Editor, Neurotoxicology 


Associate Editor, American Society for Nutritional Sciences’ Nutrition Notes 

Naisyin Wang 

Co-Editor, Biometrics 

Co-Editor, Statistical Sciences 

Associate Editor, Journal of American Statistical Association 

60


June 2006 

APPENDIX I: Toxicology Seminar Schedule 

Mondays, 11:30 AM – 12:20 PM 


Spring 2005 

Jan. 24 

Jan. 31 

Feb. 7 

Feb. 21 

Feb. 28 

Mar. 7 

Mar. 14 

Mar. 28 

Apr. 4 

Apr. 11 

Apr. 18 

Larry Johnson, PhD, Veterinary Integrative Biosciences, Texas A&M University 

“Public school - higher education interface: value of involving your graduate students and yourself” 


Paul A. White, PhD, Safe Environments Program, Health Canada 

“The Population-level Impact of Genotoxic Substances in Aquatic Systems” 


Thomas B. Knudsen, PhD, Molecular, Cellular and Craniofacial Biology, University of Louisville, School of Dentistry 

"Computational Systems Analysis of Developmental Toxicity" 


Steven G. Gilbert, PhD, DABT, Director, Institute of Neurotoxicology and Neurological Disorders 

"A Small Dose of Toxicology - Health Effects of Common Chemicals” 

Host: Larry Johnson 

Chao-Yin Chen, PhD, Dept. of Medical Pharmacology & Toxicology, University of California-Davis 

“Mechanisms Underlying Cardiovascular Consequences of Particulate Matter Exposure” 

Host: Gladys Ko 

No Seminar – Society of Toxicology annual meeting 

Patrick Grant, PhD, Lawrence Livermore National Laboratories, Center for Accelerator Mass Spectrometry 

“Nuclear Microprobe Capabilities Applied to Metalloproteomics and Other Examples” 


Arul Jayaraman, PhD, Dept. of Chemical Engineering, Texas A&M University 

“Molecular Analysis of Inflammatory Diseases: Towards Development of a Living Cell Array” 


Nasser H. Zawia, PhD, School of Pharmacy, Rhode Island University 

“Sp1 and Amyloidogenesis in the Aging Brain” 


John Lemasters, MD, PhD, Dept. of Cell and Developmental Biology, University of North Carolina at Chapel Hill 

“Alterations of Mitochondrial Membrane Permeability in Pathogenesis” 


Cole W. Matson, PhD, Dept. of Wildlife and Fishery Sciences, Texas A&M University 

“Combining Environmental Chemistry, Somatic Biomarkers and Evolutionary Toxicology: Wildlife Ecotoxicology in 

the Heavily Contaminated Industrial Zone of Sumgayit, Republic of Azerbaijan” 

Host: John Bickham 

Apr. 22 Elisabeth Christians, PhD, Centre de Biologie du Development, Toulouse, France 

Friday, 11 AM “Life without Heat Shock Factors: From Stress Response to Maternal Effect Mutation and Beyond” 

423 VMRB Cosponsored by the Center for Environmental and Rural Health Host: Philip Mirkes 

Apr. 25 

Cheryl L. Walker, PhD, U.T. M.D. Anderson Cancer Center, Science Park Research Division 

“Developmental Programming of Tumor Suppressor Gene Penetrance: Understanding How Early Life Environmental 

Exposures Can Determine Cancer Incidence in Adults” 


Apr. 26 Louis J. Guillette, Jr., PhD, University of Florida 

Tuesday, 4 PM “Alligators and Contaminants: From Populations to Genes” 

201 VMS Keynote Address for the CVM GSA Research Symposium (Co-Sponsored by Toxicology) 

May 2 

Larry Claxton, PhD, United States Environmental Protection Agency 

“Scientific Authorship: Abuses, Problems and Solutions” 


61


June 2006 

Fall 2005 


Mondays, 11:30 AM – 12:20 PM 


Oct. 3 

Oct. 10 

Oct. 17 

Oct. 24 

Oct. 31 

Nov. 7 

Nov. 14 

Nov. 21 

Nov. 28 

Dec. 5 

Dec. 12 

Mark Canfield and Peter Langlois, Birth Defects Epidemiology and Surveillance, TX Dept. of State 

Health Services 

“Birth Defects Surveillance and Research” 


Kaylee Schwertfeger, PhD, Molecular and Cellular Biology, Baylor College of Medicine 

“Early FGFR Mediated Induction of the Inflammatory Response in Breast Cancer Progression” 


Edgar C. Kimmel, PhD, US Army Edgewood Chemical and Biological Center, Aberdeen Proving Ground 

“Aerosols and the Respiratory Tract: A Review of the Fundamentals” 


Shawn Bratton, PhD, Dept. of Pharmacology, University of Texas at Austin 

“Inhibitor of Apoptosis (IAP) Proteins and Their Antagonists in Caspase-Dependent Apoptosis” 


John Fackler, PhD, Department of Chemistry, Texas A&M University 

Heavy Metal and Other Inorganic Pollutants, Medicines and Poisons Used in Murder 


Marni Bekkedal, PhD, Wisconsin Bureau of Environmental and Occupational Health 

"Hazards, Exposures, and Health Effects: Why Public Health Needs Toxicologists" 


George Stoica, PhD, Department of Veterinary Pathobiology, Texas A&M University 

“Endogenous Neurotrophin: A Sword With Two Edges” 

Host: To be determined 

Bhagavatula Moorthy, PhD, Baylor College of Medicine, 

"Regulation of Cytochrome P4501A Enzymes by Hyperoxia: Mechanistic Implications for Hyperoxic Lung 

Damage" 


Ursula Winzer-Serhan, PhD, Neuropharmacology, Texas A&M Health Science Center 

“Nicotine, Nicotinic Receptors and Development” 

Host: Louise Abbott 

Yanming Wang, PhD, Biochemistry & Molecular Biology, Pennsylvania State University 

“Histone Methylation in Gene Expression and Cancer Epigenetics” 


Hartmut Jaeschke, PhD, Liver Research Institute, University of Arizona 

“New Insight Into the Molecular Mechanisms of Drug Hepatotoxicity” 


62


June 2006 

Spring 2006 


Mondays, 11:30 AM – 12:20 PM 


Jan. 30 

Feb. 6 

Feb. 13 

Feb. 20 

Feb. 27 

Mar. 6 

Mar. 13 

Mar. 20 

Mar. 27 

Apr. 3 

Apr. 10 

Apr. 17 

Apr. 24 

May 1 

May 8 

Robert W. Biles, PhD, Senior Toxicology Advisor, ExxonMobil Biomedical Sciences 

“Toxicology/Health Science at ExxonMobil Biomedical Sciences- Issues and Careers” 

Host: Christine Naspinski 

Robert M. Greene, PhD, Molecular, Cellular and Craniofacial Biology, University of Louisville School of Dentistry 

“Integrated Signal Transduction: The Language of the Embryo" 

Host: Dr. Philip Mirkes 

Hans Schuessler, PhD, Dept. of Physics, Texas A&M University 

“Biomolecules in Vitro and in Silico” 


No Seminar 

Curtis Klaassen, PhD, Dept. of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center 

“Nuclear Receptor Regulations of Rat Hepatic Transporters” 


**Co-Sponsored by the Center for Environmental and Rural Health** 

No Seminar – Society of Toxicology 45 th Annual Meeting 

No Seminar – Spring Break 

Douglas M. Cerasoli, PhD, U.S. Army Medical Research Institute of Chemical Defense 

“Butyrylcholinesterase and Paraoxonase I - Development of Bioscavengers for Protection Against Organophosphorus 

Nerve Agents" 

Host: Dr. Jim Wild 

Mark Robson, PhD, MPH, ATS, Environmental and Occupational Health, UMDNJ-School of Public Health 

“Challenges and Opportunities for International Environmental Health Research” 

Host: Dr. KC Donnelly 

No Seminar 

Monique Rijnkels, PhD, Children’s Nutrition Research Center, Baylor College of Medicine 

“Milking the Genome: Evolution and Regulation of the Casein Gene ClusterRegion” 


Seung J. Baek, PhD, Dept of Pathology, University of Tennessee 

“Chemoprevention and NSAID Activated Gene (NAG-1)” 


Janice Chambers, PhD, Center for Environmental Health Services, Mississippi State University 

“OP Insecticides and Developing Systems: How Do We Protect the Children?” 


Carey Pope, PhD, Physiological Sciences, Center for Veterinary Health Sciences, Oklahoma State University 

"Modulation of Organophosphate Toxicity" 


David Sherr, PhD, Dept. of Environmental Health, Boston University 

"The AhR and CYP1B1 in cancer...What are they good for?" 


63

Appendix G 

Trainee Conference Participation and 

Highlights (1998-2006)

Graduate/Postdoctoral Trainees 

Conference Participation and Highlights (1998-2006) 

Conference/Symposia 

Year Attendees 

Highlights 

American Academy of Veterinary Pharmacology & Therapeutics 

2003 1 

American Association for Cancer Research (AACR) 

2004 6 

2005 9 

2006 6 

American Association for the Study of Liver Disease 

2003 2 

American Association of Pharmaceutical Scientists 

2006 5 

American Association of Veterinary Anatomists 

2003 1 Sairam Bellum- 2 nd Place Poster 

2004 1 

American Chemical Society (ACS) 

1999 2 

2000 1 Shawna Lemke –2000 AGFD Graduate Research Award; ACS Travel Award 

American College of Toxicology (ACT) 

2003 1 

2005 1 Atrayee Banerjee- ACT Travel Award 

2006 1 

American College of Veterinary Clinical Pharmacology 

2002 1 

American College of Veterinary Internal Medicine 

2002 1 

2003 1 

American College of Veterinary Medicine 

2001 1 

American Heart Association Atherosclerosis, Thrombosis & Vascular Biology 

2003 1 

2004 1


2002 1 

Conference on Hazardous Waste Research: Environmental Challenges and Solutions to 

Resource Development, Production and Use 

2000 1 

Contemporary Concepts in Toxicology, Mechanisms of Nephrotoxicity and 

Nephrocarcinogenicity Conference 

2000 2 Napoleon Alejandro – Conference Travel Award 

Dioxin 

1998 1 

2000 1 

Endocrine Society (ENDO) 

2001 4 Brad Saville- Biochemistry Travel Award 

Kelcey Walker- CVM-GSA Travel Award 

2004 3 

2005 8 Fei Wu- ENDO Travel Award 

2006 3 

Enzyme 2001 

2001 2 

Euro Conference on Mechanisms of Cell Death and Disease 

2006 1 Kathy Vanderlaag – Conference Travel Award 

Federation of American Societies for Experimental Biology (FASEB) 

1999 1 Kevin Kerzee–NAVBO Young Investigator Award 

Genes, Dogs and Cancer Conference 

2006 1 

Gordon Research Conference 

2000 2 

2001 2 Jeong Eun Lee - CVM-GSA Travel Award 

Qian Wu - Biochemistry Travel Award 

2003 10 

2005 1 

Gulf Coast Chapter, Society of Toxicology (GCSOT) 

1998 42 Matthew Stoner – 3 rd Place Platform 

Kim Poe Lu – 3 rd Place Poster 

I-Chen Chen – Honorable Mention Poster 

Weili Wang – 2 nd Place Postdoctoral Poster 

1999 39 Matthew Stoner – 3 rd Place Poster 

Kevin Kerzee – Honorable Mention Platform 

Yongchang Qian – Postdoctoral Award

2000 35 

2002 52 TAMU hosted this meeting 

Karin Lum- 2 nd Place Platform 

Kelcey Walker- Honorable Mention Platform 

Charlie Partridge- 2 nd Place Poster 

Spencer Williams- Honorable Mention Poster 

2003 19 Tracie Phillips- Honorable Mention Poster 

2004 3 Sudhakar Chintharlapalli- 2 nd Place Platform 

2005 12 Tanya Gustafson- 1 st Place Platform 

Kathryn Vanderlaag- 3 rd Place Platform 

Brian Laffin- 2 nd Place Poster 

2006 3 

Homeland Food and Water Security Workshop 

2002 1 

17 th International Neurotoxicology Conference 

1999 1 Lora Lindahl – 3 rd Place Poster 

International Symposium on Applications of Enzymes in Chemical & Biological Defense 

2001 1 

International Symposium on Recent Advances in Food Analysis 

2003 2 

Jensen Symposium 

2003 2 

Keystone Symposia 

1999 2 

2006 1 

Lost Pines Molecular Biology Conference 

1999 1 

2005 5 

Neural Tube Defects Conference 

2003 4 

2005 7 

Neurodegeneration and Recovery of Function Symposium 

2004 5 Xuhong Liu- 3 rd Place Poster 

NIEHS Center for Environmental & Rural Health (CERH) Scientific Symposia 

2003 40 

2004 25 Jeong Eun Lee – 1 st Place Poster 

2005 32 Atrayee Banerjee -Tied for 1st Place Poster 

Xinsheng Gu -Tied for 1st Place Poster 

Tanya Gustafson - 2nd Place Poster

Sudhakar Chintharlapalli - 3rd Place Poster 

NIEHS 7 th International Congress on Combustion By-Products 

2001 3 Erica Reese- NIEHS Travel Award 

NIEHS Superfund Basic Research Program Annual Meeting 

2000 2 

2001 2 

2002 3 

2003 3 Denise Hill- Best Poster Award, Biomedical Research 

Tracie Phillips- Best Poster Award, Non-Biomedical Research 

2004 3 

2005 5 Denise Hill- Best Poster Award, Biomedical Research 

2006 3 

NIEHS-USEPA Central and Eastern European Conference on Environment and Health (CEECHE) 

2004 12 TAMU co-sponsored this meeting in Prague, CZ 

Petros Dimitriou-Christidis – Poster Presentation Award 

Tracie Phillips – Platform Presentation Award 

2006 9 TAMU co-sponsored this meeting in Bratislava, SK 

Christine Naspinski –Honorable Mention Platform 

Proteomics Conference 

2002 2 

Rocky Mountain/Great Plains Region Hazardous Substance Research Conference 

1999 1 

SiRNA Wet Lab Course 

2006 2 Dr. Marianne Barrier –NIEHS Training Grant support 


2005 4 Kerry Thuett- NIEHS Training Grant support 

Society for the Study of Reproduction Annual Meeting 

2005 1 Dr. Frankie White – 2005 USDA National Research Initiative Merit Award 

Society of Armed Forces Medical Laboratory Scientists 

2002 2 

Society of Environmental Toxicology & Chemistry (SETAC) 

1998 1 

1999 2 

2002 4 

2003 4 

2004 1 

2005 1

Society of Toxicology (SOT) 

1999 42 Kevin Kerzee – Proctor & Gamble Graduate Fellowship 

Kim Poe Lu – 1 st Place, In Vitro 

Andrew McDougal – 2 nd Place, Food Safety 

Kim Miller – 2 nd Place, Comparative and Vet. 

Chunhua Qin – 2 nd Place, Molecular Biology 

Kevin Kerzee – Honorable Mention, Mechanisms 

Yun-Houng Chen - SOT Travel Award 

Napoleon Alejandro – CVM-GSA Travel Award 

I-Chen Chen – CVM-GSA Travel Award 

Mona Gupta – CVM-GSA Travel Award 

Marc Holderman – CVM-GSA Travel Award 

Henry Huebner – CVM-GSA Travel Award 

Kim Poe Lu – CVM-GSA Travel Award 

Andrew McDougal – CVM-GSA Travel Award 

Kim Miller – CVM-GSA Travel Award 

Chunhua Qin – CVM-GSA Travel Award 

Kavita Ramamoorthy – CVM-GSA Travel Award 

Matthew Stoner – CVM-GSA Travel Award 

Mark Wormke - CVM-GSA Travel Award 

2000 40 I-Chen Chen – 1 st Place, In Vitro 

Yun-Houng Chen – 1 st Place, Mechanisms 

Shawna Lemke – SOT Travel Award 

Chunhua Qin – SOT Travel Award 

Emely Castro-Rivera – CVM-GSA Travel Award 

Yun-Houng Chen – CVM-GSA Travel Award 

Tae-Hyeon Cho – CVM-GSA Travel Award 

Andrew McDougal – CVM-GSA Travel Award 

Derek Morrow – CVM-GSA Travel Award 

Matthew Stoner – CVM-GSA Travel Award 

Kim Miller – Women’s Faculty Network Travel Award 

2001 37 Dr. Kevin Kerzee- Colgate-Palmolive Postdoc Fellowship 

Chien-Cheng Chen- CVM-GSA Travel Award 

Tae-Hyeon Cho- CVM-GSA Travel Award 

Shaheen Khan- CVM-GSA Travel Award 

Wan-Ru Lee- CVM-GSA Travel Award 

Kim Miller- CVM-GSA Travel Award 

Matt Stoner- CVM-GSA Travel Award 

2002 30 Dr. Ron Tjalkens- Amer. Chemistry Council Early Award in Neurotoxicology 

Spencer Williams- Covance Graduate Student Fellowship 

Dr. Charlie Johnson- Best Abstract-Occupational Health 

Spencer Williams- 2 nd Place, In Vitro 

Hadi Falahatpisheh- 3 rd Place, Mechanisms 

Brad Saville- Honorable Mention, Mechanisms 

Jeong-Eun Lee- SOT Travel Award 

2003 31 Dr. Udayan Apte- 2 nd Place Comparative and Veterinary Specialty 

Dr. Kimberly Miller- Colgate-Palmolive Postdoctoral Award 

Maen Abdelrahim- SOT Travel Award 

Evans Afriyie-Gyawu- CVM-GSA Travel Award

Kelly Higgins- Biochemistry Travel Award 

Xiangrong Li- CVM-GSA Travel Award 

Adrian Nañez- SOT Travel Award 

Kerry Thuett- Neuroscience Travel Award 

Kelcey Walker- CVM-GSA Travel Award 

Mindy Wiles- CVM-GSA Travel Award 

Fei Wu- Biochemistry Travel Award 

Qian Wu- Biochemistry Travel Award 

Shu Zhang- CVM-GSA Travel Award 

2004 28 Evans Afriyie-Gyawu- CVM-GSA Travel Award 

Sairam Bellum- CVM-GSA and Neuroscience Travel Awards 

Dr. Henry Huebner- NIEHS Training Grant support 

Xuhong Liu- SOT and CVM-GSA Travel Awards 

Tracie Phillips-CVM-GSA Travel Award, NIEHS Training Grant support 

Kerry Thuett- CVM-GSA & Neuroscience Travel Awards 

Mindy Wiles- NIEHS Training Grant support 

Fei Wu- Biochemistry Travel Award 

2005 37 Sairam Bellum- CVM-GSA Travel Award 

Dr. Henry Huebner- NIEHS Training Grant support 

Rebecca Lingenfelter-NIEHS SBRP support 

Tracie Phillips- NIEHS Training Grant support 

Kerry Thuett- CVM-GSA Travel Award, NIEHS Training Grant support 

2006 22 Dr. Rola Barhoumi-Colgate-Palmolive Grant for Alternative Research 

Natalie Malek– Pfizer Award 

Sudhakar Chintharlapalli– SOT Travel Award 

Tracie Phillips- NIEHS Training Grant support 

Kerry Thuett- NIEHS Training Grant support 

Society for Toxicologic Pathology 

2006 1 Atrayee Banerjee – 3 rd Place, Young Investigator Award and 

Conference Travel Award 

Teratology Society 

2004 1 

2005 2 Dr. Marianne Barrier – Teratology Society Travel Award; NIEHS 

Training Grant support 

Hiromi Hosako – Teratology Soc. Travel Award 

2006 2 Dr. Marianne Barrier-Teratology Soc. Travel Award, NIEHS 

Training Grant support 

Hiromi Hosako-Teratology Soc. Travel Award 

Texas Forum on Female Reproduction (TFFR) 

1999 8 

2000 6 

2001 2 

2002 7 Maen Abdelrahim- Life Science Task Force (LSTF) Travel Award 

Shaheen Khan- LSTF Travel Award 

Leela Kotha- LSTF Travel Award 

Xiangrong Li- LSTF Travel Award

2003 5 

Sharon Ngwenya- LSTF Travel Award 

Dr. Matt Stoner- LSTF Travel Award 

Shu Zhang- LSTF Travel Award 

Texas Research Society on Alcoholism, Scientific Meeting 

2004 2 Dr. Udayan Apte- John McGovern Award 

TAMU College of Veterinary Medicine Graduate Student Symposium 

2006 25 Sabitha Papineni – 2 nd Place Poster 

Brian Laffin – 4 th Place Oral Presentation 

TAMU Student Research Week 

1999 9 Bill Reeves – 1 st Place, Life Sciences Poster 

Andrew McDougal – 1 st Place, Biomedical Poster 

2000 3 Bill Reeves – 1 st Place Biological Sciences Poster 

2006 5 Kerry Thuett – 2 nd Place Life Sciences Poster 

TAMU Toxicology Graduate Symposium 

2004 43 Xiangrong Li- 1 st Place Platform 

Sairam Bellum- 1 st Place Poster 

Sudhakar Chintharlapalli- 2 nd Place Poster 

Annika Gillespie- 3 rd Place Poster 

2005 55 Kathy Vanderlaag- 1 st Place Platform 

Shu Zhang - 2 nd Place Platform 

Henry Kwak - 1 st Place Poster 

Atrayee Banerjee- 2 nd Place Poster 

Tanya Gustafson- 3 rd Place Poster 

2006 45 Atrayee Banerjee – 1 st Place Platform (tie) 

Brian Laffin –1 st Place Platform (tie) 

Tracie Philips - 1 st Place Poster 

Elizabeth Wellberg - 2 nd Place Poster 

Ying Xie - 3 rd Place Poster 

US Grains Council’s International Grains and Future Markets Conference 

1998 1 Henry Huebner – conference travel award 

University of Texas MD Anderson’s Molecular Targets for Cancer Symposium 

1999 5 

Vitron Laboratories Workshop 

2002 1

Appendix H 

Current Student Awards and Honors

IFT Current Graduate Student Awards and Honors 

Atrayee Banerjee 

• First Place Platform Presentation, TAMU Toxicology Graduate Student Forum (2006) 

• Third Place, Young Investigator Award, and Student Travel Award, 25 th Annual Symposium, Society 

of Toxicologic Pathology, Vancouver, Canada (2006) 

• George T. Edds Award for Outstanding Toxicology Graduate Student, TAMU College of Veterinary 

Medicine and Biomedical Sciences (2006) 

• First Place, Poster Presentation, TAMU Center for Environmental and Rural Health Annual 

Symposium, College Station (2005) 

• Academy of Toxicological Sciences student travel grant, American College of Toxicology (2005) 

• Graduate Student Association travel grant, TAMU College of Veterinary Medicine and Biomedical 

Sciences (2005) 

• Second Place, Poster Presentation, TAMU Toxicology Graduate Student Forum (2005) 

• John P McGovern Student Fellowship, Texas Research Society on Alcoholism (2005) 

• First Place, Platform Presentation, Graduate Research Symposium, TAMU College of Veterinary 

Medicine (2005) 

• Regents’ Fellowship, Texas A&M University (2004-2005) 

• South Texas Environmental Health Outreach Program Scholarship (2003-2004) 

• Second Place, Young Scientist Award, Science Congress, India (2002) 

Xinsheng Gu 



• Graduate Student First Place Poster, TAMU Center for Environmental and Rural Health Scientific 

Symposium (2005) 

• The editor of the book Chinese edition of Neuroscience Year. published in 2000. Award of Scientific 

and Technological Book in East China. 

• The editor of the book Molecular Diagnosis and Gene therapy of Genetic Diseases Published in 

1999, Co-authored by Zeng Yitao and other 8 scientists of medical genetics. The 10 th National Award 

for Excellent Scientific and Technological Books. 

Tanya Gustafson 

• Howard Hughes Medical Institute Predoctoral Fellowship in Biological Sciences (2003-present) 

• Dr. William F. Egan ’43 Memorial Award (2003) 

• Benjamin G. Brown Scholarship for Scientific Research (2002) 

• Class of 1947 Victor Prather Prize (2002) 

• Margaret D. Angell and Henrietta B. Durkee Scholarship in Chemistry (2002) 

• Max Tishler Prize Scholarship in Chemistry (2001) 

• R.M. Karapetoff Cobb Chemistry Fund (2001) 

• Thomas H. Carmichael & Emily L. Carmichael Prize Scholarship in Physiology (2001) 

• Elected to Phi Beta Kappa (2001) 

• Dean’s Prize (1999) 

• Anna Q. Churchill Prize in Biology (1999) 

Denise Hill 

• Travel Award, Central and Eastern European Conference on Health and the Environment, Bratislava, 

Slovakia (2006) 

• NIEHS Toxicology Training Grant Fellowship, Texas A&M University (2004-2007)

• NIEHS Superfund Basic Research Program, Best Student Poster in Biomedical Research (2003 and 

2006) 

• Travel Award, NIEHS Superfund Basic Research Program (2003 and 2006) 

• Teratology Society, Wilson Presentation Award (2003 and 2006) 

Hiromi Hosako 

• Young Investigator Travel Award, Teratology Society 46 th Annual Meeting (2006) 

• Travel Award, TAMU College of Veterinary Medicine Graduate Student Association (2006) 

• Outstanding Senior Undergraduate Award, Chemistry and Biochemistry Department, Texas State 

University (2004) 

• Louis Stokes Alliance for Minority Participation Scholarship - LSAMP (2003) 

• 1 st place Oral Presentation Award, Southwest Regional Student Conference, LSAMP (2003) 

• Academic Excellence Award, Biology Department at Texas State University (2002) 

• Scholarship Grant, The School for Field Studies (SFS, 2002) 

• Study Abroad Scholarship, Texas State University (2002) 

• Dean’s list, Texas State University (2000-2002) 

Natalie Johnson 

• Regents’ Fellowship, Texas A&M University (2006) 

• Pfizer Undergraduate Travel Grant for Society of Toxicology Meeting (2006) 

• Invited Undergraduate Research Presentation at the Society of Toxicology Undergraduate Education 

Program (2006) 

• Interdisciplinary Research Recognition Award at TAMU Student Research Week (2006) 

• Phi Beta Kappa Honor Society Member 

Matthew Kelley 

• Member, Texas A&M chapter of Tri-Beta National Biological Honor Society 

• HAZWOPER certified 

Rory Kern 

• NIEHS Toxicology Training Grant Fellowship, Texas A&M University (2003-2007) 

• TAMU Distinguished Student (1996) 

• TAMU Sul Ross Scholarship (1996-1997) 

Brian Laffin 

• TAMU Academic Excellence Award (2005-2006) 

• Charles J. Koerth Memorial Scholarship (2006-2007) 

• Second Place Poster Presentation, Gulf Coast Society of Toxicology annual meeting, Austin, TX 

(2005) 

• First Place Oral Presentation, TAMU Student Research Week (2006) 

• Fourth Place Oral Presentation, TAMU College of Veterinary Medicine Graduate Student Association 

Research Symposium (2006) 

• First Place Oral Presentation, TAMU Faculty of Toxicology Graduate Student Research 


• First Place Poster Presentation, TAMU Veterinary Integrative Biosciences Departmental 


Boyeon Lee 


• Academic scholarship, College of Veterinary Medicine, Chonnam National University (1999-2000)

Wan-Ru Lee 

• Graduate Student Association travel grant, TAMU College of Veterinary Medicine and Biomedical 

Sciences (2001, 2005) 



• Regents’ Graduate Fellowship, Texas A&M University (1999-2000) 

• Graduate Research Fellowship, Taiwan Ministry of Education (1994-1996) 

Alicia Marroquin-Cardona 

• Sponsored Student Graduate Fellowship, Programa de Mejoramiento del Profesorado (PROMEP), 

Mexico (2006-2009) 

Christine Naspinski 


• Travel Award, Central and Eastern European Conference on Health and the Environment, Bratislava, 

Slovakia (2006) 

• Graduate Merit Fellowship, TAMU Association of Former Students (2003-2005) 

Ziad Naufal 

• Third Place Poster Presentation at the US Environmental Protection Agency Science Forum (2006) 

• Invited member of the Honor Society of Phi Kappa Phi 

Sabitha Papineni 

• Travel Award, TAMU College of Veterinary Medicine Graduate Student Association to attend the 

Society of Toxicology annual meeting in New Orleans, Louisiana (2005) 

• Travel Award, TAMU College of Veterinary Medicine Graduate Student Association to attend the 

AACR Annual Meeting in Washington, D.C. (2006) 

• Second Place Poster Presentation in the TAMU College of Veterinary Medicine Graduate Student 

Association Research Symposium (2005) 

• TAMU International Student Education Fee Scholarship.(2006) 

Tracie Phillips 


• First Place Poster Presentation, TAMU Toxicology Graduate Student Forum (2006) 

• HAZWOPER Hazardous Waste Operations and Emergency Response certified (recertification in 

2006) 

• Outstanding Platform Presentation and Travel Award, Central and Eastern European Environmental 

Health Conference, Prague, Czech Republic (2004) 

• Honorable Mention Platform Presentation, Gulf Coast Society of Toxicology annual meeting, 

Galveston, Texas (2003) 

John Taylor 

• Burdock Group Travel Award, Society of Toxicology (2005) 

Kerry Thuett 


• Travel Awards, TAMU Faculty of Neuroscience (2003-2006) 

• Travel Awards, College of Veterinary Medicine Graduate Student Association (2004-2006) 

• TAMU Neuroscience Research Competition, Fourth Place (2006) 

• TAMU Student Research Week, Second Place Poster Presentation (2006) 

• TAMU Student Research Week, First Place Poster Presentation (2005)

• TAMU College of Veterinary Medicine Graduate Student Association Research Symposium Platform 

Presentation Award, Honorable Mention (2005) 

• Society of Toxicology Student Travel Award (2005) 

• George Bush Library Research and Travel Award (2004) 

• Office of Graduate Studies Research Award (2004) 

• TAMU Student Research Week, First Place Research Presentation (2004) 

Kathryn Vanderlaag 

• Travel Award, TAMU College of Veterinary Medicine Graduate Student Association (2004-2006) 



• First Place, Student Platform Presentation, TAMU Toxicology Graduate Student Symposium (2005) 

• Third Place, Student Platform Presentation, Gulf Coast Society of Toxicology Meeting (2005) 

• Cooperative Education Student Award, University of Guelph (2001) 

Elizabeth Wellberg 


• Second Place Poster Presentation, TAMU Toxicology Graduate Student Symposium (2006) 

• TAMU Regents’ Fellowship (2004-2005) 

Ying Xie 

• First Place Poster Presentation, TAMU Toxicology Graduate Student Symposium (2006) 

Melissa York 

• Graduate Merit Fellowship, TAMU Association of Former Students (2004-2006) 

Shu Zhang 


• Second Place, Student Platform Presentation, TAMU Toxicology Graduate Student Symposium 

(2005)

Appendix I 

Faculty Awards and Honors

IFT Faculty Awards and Service 

Louise Abbott, Associate Professor 

• Samuel F. Scheidy Memorial Award for Research Excellence, American Veterinary Medical 

Association (1999) 

• TAMU Montague Center for Teaching Excellence Scholar (1997-1998) 

• Fulbright Research Scholarship, Paris, France (1994) 

• College of Veterinary Medicine Teaching Award, University of Illinois (1993) 

• SAVMA Veterinary Medical Teaching Excellence Award in Basic Sciences, University of 

Illinois (1990) 

• Arnold O. Beckman Research Award, University of Illinois (1989) 

• Fellowship, Developmental Biology Training Program, University of Washington (1977-1981) 

• Ad hoc reviewer: American Journal of Veterinary Research, Journal of the American 

Veterinary Medical Association, Journal of Neuroscience Methods, International Journal of 

Developmental Neuroscience, Journal of Neurobiology, Journal of Neurogenetics, Journal of 

Neuroscience, Journal of Neuroscience Methods, Journal of Neuroscience Research, 

Journal of Neurochemistry, Brain Research, Brain Research Reviews, Brain Research 

Protocols, Neuroscience, Neuroscience Letters, Neurobiology of Learning and Memory, 

Neurotoxicity Research, Toxicology Letters, In Vitro Toxicology 

• Grant Review Committees: NIH Ad Hoc Study Section BDCN-1 (2001-2003); NIH Study 

Section CND, Ad Hoc Member (2003-2006); USDA National Research Initiative Competitive 

Grants Program, Ad Hoc reviewer (2001 and 2003) 

Clinton Allred, Assistant Professor 

• Abstract in Research Summaries Book at the Endocrine Society’s Annual Meeting (2005) 

• David H. Baker Nutrition Scholar Award (2003) 

• Food Safety Specialty Section Graduate Student Award at SOT (2000) 

• Professional and Honorary Societies: The Endocrine Society, American Society of 

Nutritional Sciences, Society of Toxicology, Midwest Society of Toxicology, Gamma Sigma 

Delta Agriculture Honor Society 

Robin Autenrieth, Professor 

• A.P. & Florence Wiley Professorship III (2004-2007) 

• Aldo Leopold Leadership Fellow (2004) 

• TAMU Neely ‘52/Dow Chemical Fellow (2003-2004) 

• TAMU Zachary Award for Excellence in Teaching (1991) 

• Way Cool Scientist, Bill Nye the Science Guy Trading Cards (1996) 

• Texas Engineering Experiment Station Research Fellow (1996-1997) 

• Professional License: Registered Professional Engineer in Texas No. 77555 

• Professional and Honorary Societies: American Society of Civil Engineers, American 

Chemical Society (Division of Environmental Chemistry), Association of Environmental 

Engineering & Science Professors, Association of Women in Science, Chi Epsilon (Civil 

Engineering Honor Society), International Association on Water Quality, Water Environment 

Federation 

Judith Ball, Associate Professor 

• TAMU College of Veterinary Medicine Nominee, Montague Scholars Teaching Award (1999)

• TAMU Council of Principle Investigators, College of Veterinary Medicine representative 

(1999) 

• TAMU Nominee for the David and Lucile Packard Fellowship (1998) 

• TAMU Nominee for the Searle Scholar Program (1998) 

• Dr. Chris Noonan Award, Molecular Virology Department, Baylor College of Medicine (1997) 

• Postdoctoral fellowship, Training Grant No. AI 07150-13; “Basic Mechanisms in Virology”, 

University of Alabama at Birmingham (1991-1993) 

• Certifications: American Society of Clinical Pathologists (ASCP) Medical Technologist, 

1974; U.S. Department of Agriculture Certification, National Veterinary Services 

Laboratories, Ames, Iowa (1981) 

• Grant Review Committees: National Initiative Competitive Grants Program, USDA, Animal 

Health & Well-Being, Panel A, Virology & Viral Immunity, 1998); Office of Scientific Quality 

Control Panel, USDA, ARS, NP103 Animal Health – Virology and Prion Disease (2001); 

Panel Member, National Initiative Competitive Grants Program, USDA, Animal Health & 

Well-Being, Panel A, Virology & Viral Immunity (1998, 2003); National Initiative Competitive 

Grants Program, CREES, USDA, Animal Protection, Panel B (2004); Panel Manager, 

National Initiative Competitive Grants Program, CREES, USDA, Animal Protection (2005- 

2006) 

• Ad hoc reviewer: National Initiative Competitive Grants Program, USDA, Animal Health & 

Well-Being Program, Virology & Viral Immunity (1999); National Initiative Competitive Grants 

Program, USDA, Animal Health & Well-Being Program, Virology & Viral Immunity(2000); 

National Initiative Competitive Grants Program, USDA, Animal Health & Well-Being 

Program, Virology & Viral Immunity (2001); National Institutes of Health, NIH/NIAAA, 

National Institute on Alcohol Abuse and Alcoholism (2004) 

Catherine Barr, Adjunct Professor 

• Certifications/Licenses: Diplomate, American Board of Toxicology (2000), Re-certified 

American Board of Toxicology (2005) 

• Professional and Honorary Societies: American Association for Veterinary and Comparative 

Toxicology, Past President (2003–2005), President (2001–2003), Vice President/President 

Elect (1999–2001), Fellow-elected (1999), Student Fellow-elected (1996), AAVCT Liaison to 

Vet Analytical Tox Steering Committee (1998-2003); Veterinary Analytical Toxicology 

Steering Committee (1995-1998); Mycotoxin Committee (1995-2001); American Association 

of Veterinary Laboratory Diagnosticians, Approved Methods Committee (2004-2006); 

Veterinary Analytical Tox Steering Committee (2003-2007), Program Committee (2002- 

2006); Association of Official Analytical Chemists, International; American Association for the 

Advancement of Science; American Chemical Society (1986-1997) 

Lori Bernstein, Assistant Professor 

• NIH Training Grant, John Hopkins University 

• Predoctoral Intramural Research Training Award, National Institutes of Health 

• Postdoctoral Intramural Research Training Award, National Cancer Institute 

• Chair, DNA Binding Proteins in Regulation of Gene Expression and Genomic Stability 

symposium 

• Keynote speaker for Annual International Conference: American Academy of Anti Aging 

Medicine, “Genetic Instability and its Implications on an Aging Population.” 

• Keynote speaker for general session, American Academy of Anti-Aging Medicine 

• Harvard University Dean’s List 

• Aggasiz Award, Radcliffe College 

• Magna Cum Laude in Biochemical Sciences, Harvard

• Ad Hoc Reviewer: Gene, Molecular Carcinogenesis, International Journal of Cancer, 

Molecular Cancer Research, and Cytokine 

• Professional and Honorary Societies: American Association for Cancer Research (AACR); 

ASBMB (FASEB) 

Gerald Bratton, Professor and Department Head 

• American Association of Veterinary Anatomists, Outstanding Veterinary Anatomist of the 

Year (2005) 

• Association of Former Students, University Level Distinguished Teaching Award (2003) 

• Norden Distinguished Teaching Award, Texas A&M University (2003) 

• Texas Veterinary Medical Association Award in Teaching (2002) 

• Wiley Professorship (2001) 

• Association of Former Students, College Level Distinguished Teaching Award (2000) 

• John H. Milliff Award for Teaching (2000) 

• Former Students Association Distinguished Achievement Award for Administration (1992) 

• Texas Veterinary Medical Association Research Award (1986) 

David L. Busbee, Professor 

• TAMU Distinguished Achievement Award for Teaching (1998) 

• George W. Bush, State of Texas Commendation for Research Excellence (1996) 

• Fisher Foundation for Medical Research-Edwards Award for Research Excellence (1995) 

• Carrington Award for Research Excellence (1995) 

• President, American Aging Association (1992) 

• TAMU Distinguished Achievement Award for Research (1989) 

• Board of Directors, American Aging Association (1987-95) 

• Beecham Award For Research Excellence (1987) 

• Beta Beta Beta Outstanding Professor 

• Mortar Board Outstanding Educator 

• Professional and Honorary Societies: Society of Toxicology, American Aging Association, 

Society for Marine Mammal Science, American Society for Cell Biology and Biochemistry, 

Golden Key National Honor Society 

Robert Burghardt, Professor and Chair of IFT 

• TAMU Agriculture Program Vice Chancellor’s Award in Excellence for Team Research 

(2005) 

• Wiley Distinguished Teaching Professorship in Veterinary Medicine (2000-2003) 

• Association of Former Students, Level College Distinguished Teaching Award (1995) 

• Carrington Veterinary Medical Division Faculty Research Award in Cell Biology and 

Immunology, College of Veterinary Medicine (1994) 

• Ford Foundation Postdoctoral Fellowship, Laboratory of Reproduction and Reproductive 

Biology, Harvard Medical School (1976-1978) 

• Editorial Responsibilities: Associate Editor, Biology of Reproduction (1992-1995); Editorial 

Board Member, Cells, Tissues, Organs (2004-present); Referring Editor, Biology of 

Reproduction: Responsible for editorial oversight for appeals to Editor-in-Chief for contested 

decisions, (2001-2004); Editorial Board, Journal of Applied Toxicology (2006-present)

• Grant Review Committees: NSF Cell Biology Program, Ad hoc reviewer (1986); NSF 

Physiological Processes Program, Ad hoc reviewer (1991); NSF Signal Transduction and 

Regulation Program, Ad hoc reviewer (1995); NSF Integrative Animal Biology Program, Ad 

hoc reviewer (2001-2003); NIH Program Project Grant Review, Maternal and Child Health 

Research Committee, National Institute of Child Health and Human Development (1990-91); 

NIH Biochemical Endocrinology Study Section, Child Health and Human Development, 

Pathophysiology of Endometriosis and Leiomyomata Uteri (1992); NIH National Institute of 

General Medical Sciences, Special Emphasis Panel, MBRS Supplemental Instrumentation 

Grant Applications (1996); NIH Temporary Member, Human Embryology and Development 

(HED-1) Study Section (2002); NIH Temporary Member, Human Embryology and 

Development (HED-1) Study Section, (2004); NIH Member, NIEHS Environmental Health 

Sciences Review Committee Member, site-visit team reviewing NIEHS Center Grant 

Application (2004); NIH/NIGMS MBRS ES SEP Review Committee Member (2004); NCI 

Role of the Microenvironment in Breast Cancer (1994); Louisiana Education Quality Support 

Fund Research and Development Program. Ad hoc reviewer for Board of Regents (1992); 

Veterans Health Administration (VHA) Department of Veterans Affairs, Medical Research 

Service, Ad hoc reviewer, January (1992); VHA Environmental Hazards Research Centers 

Review Committee (1999); March of Dimes Birth Defects Foundation, Ad hoc reviewer 

(1996); USDA National Research Initiative Competitive Grants Program, Ad hoc reviewer 

(1994); USDA Binational Agricultural Research Development (BARD) Program, Ad hoc 

reviewer (1998); USDA Animal Reproductive Efficiency Program, Ad hoc reviewer (1998- 

2000, 2004); Israel Science Foundation, administered by the Israel Academy of Sciences 

and Humanities, Ad hoc reviewer (1993, 1998);Natural Sciences and Engineering Research 

Council of Canada (2001); March of Dimes Central Texas Chapter, Grants Review 

Committee (1999-2002); Wellcome Trust, Joint Infrastructure Fund, UK (1999); South Plains 

Foundation (2002); Grant review for Pilot Interdisciplinary Research Projects from The BIO5 

Institute, University of Arizona (2006) 

James Calvin, Professor and Executive Associate Vice President for Research 

• Don Owen Award, American Statistical Association (2002) 

• JASA–Applications and Case Studies Invited Paper, Joint Statistical Meeting (2001) 

• Fellow, American Statistical Association (2000) 

• James L. Madison Award, Colorado State University (1985) 

• Grant Review and Scientific Advisory Committees: National Research Council NIST 

Information Technology Assessment Panel (2003-2007); ASA Wilks Memorial Award 

Committee (2003-2004); NIEHS EHS Review Committee (2002–2007), Chair (2005-2007); 

Chair, Academic Heads Meeting, Joint Statistical Meetings (2002); Program Committee, 

Board of Mathematical Sciences Chairs’ Colloquium (2001); Program Committee, Inaugural 

Graybill Conference on Linear Models and its Applications (2001); Program Chair, Statistical 

Education, 1989 JSM, Washington, D.C. (1988-1989) 

• Editorial Responsibilities: Editorial Board Member, ASA/SIAM Series on Statistics and 

Applied Probability (1999-2002); Executive Editor, Biometrics (1997-2000); Associate Editor, 

Journal of the American Statistical Association (1996-1999); Organizing Editor, Special 

Issue in Honor of Robert V. Hogg, Central Regional Meeting of IMS/ASA, Communications 

in Statistics (1996); Associate Editor, Communications in Statistics (1992-2001) 

• Ad Hoc Referee for: National Science Foundation, National Institute of Environmental Health 

Sciences (1985-present),.and numerous journals, including JASA, Annals of Statistics, 

Technometrics, Communications in Statistics, JSPI, Journal of Multivariate Analysis, 

Statistics & Probability Letters, Chemometrics and Intelligent Laboratory Systems, Statistics, 

IIE Transactions

• Professional and Honorary Societies: International Statistical Institute, Institute of 

Mathematical Statistics, International Biometric Society, American Statistical Association, 

Council of Chapters Representative, Southeast Texas Chapter of ASA (1992–1994), ASA 

Advisory Committee on Continuing Education (1988–1990), Iowa Chapter of ASA (1986- 

1988), President (1987–1988), ASA Strategic Planning – Meetings and Member Support 

Task Force (1997), ASA Committee on Membership. Chair of Individual Membership 

Subcommittee (1993–1998), Chair of Committee on Membership (1997–1998) 

Raymond Carroll, Distinguished Professor 

• National Cancer Institute MERIT Award (2005-2015) 

• TAMU Association of Former Students, Distinguished Achievement in Research (1994, 

2004) 

• TAMU College of Science Teaching Award (2003) 

• National Institute of Statistical Science, Sacks Award for Cross-Disciplinary Research (2003) 

• International Society for Bayesian Analysis, Mitchell Prize for Bayesian Statistics (2003) 

• Fisher Lecture, Committee of Presidents of Statistical Societies-COPSS (2002) 

• Snedecor Award from COPSS for best paper in Biometry (1997) 

• Alexander von Humboldt Senior Research Award (1996) 

• TAMU Outstanding Achievement Award for Promoting Diversity (1996) 

• Society of Toxicology Outstanding Presentation Award, Risk Assessment Section (1995) 

• President's Invited Address, ENAR Spring Meeting (1995) 

• Distinguished Alumnus, Purdue University (1994) 

• Don Owen Award (1994) 

• Distinguished Lecturer in Statistics, Australian Graduate School of Management (1991) 

• COPSS President's Award (1988) 

• Wilcoxon Prize, American Society for Quality Control (1986) 

• Editorial Responsibilities: Editor, Biometrics (1997-2001); Editor, Journal of the American 

Statistical Association, Theory and Methods Section (1988-1990); Coordinating Editor, 

Journal of Statistical Planning & Inference (1992-1998); Co-editor, Oxford Statistical Science 

Series (2000-present); Co-editor, Royal Statistical Society Lecture Note Series (1995-1999); 

Associate Editor, Journal of the American Statistical Association (1979-1987, 1992-1995); 

Associate Editor, Annals of Statistics (1983-1988); Associate Editor, Chemometrics & 

Intelligent Laboratory Systems (1986-1992); Associate Editor, Journal of Environmental 

Statistics (1992-present); Associate Editor, Statistica Sinica (1993-present); Associate Editor, 

Statistics (1987-present) 

Robert Chapkin, Professor 

• Sigma Xi Distinguished Scientist Award, Texas A&M University Chapter (2006) 

• Texas A&M University Faculty Fellow (2001-2005) 

• Texas Agricultural Experimentation Station Faculty Fellow (2000) 

• American Society for Nutritional Sciences BioServ Award in Experimental Animal Nutrition 

(1996) 

• American Oil Chemists' Society, Outstanding Paper Presentation (1995) 

• PEW National Nutrition Program Faculty Scholar (1991-1992) 

• National Institutes of Health "First Award" (July 1989-June 1994) 

• Professional and Honorary Societies: American Society for Nutritional Sciences (1989- 

Present); Federation of American Societies for Experimental Biology (1989-Present); Sigma 

Xi (1991-Present); American Association for Cancer Research (1993-Present); American 

Society for Cell Biology (2004-Present)

• Editorial Responsibilities: Associate Editor, American Society for Nutritional Sciences 

Newsletter (1993-1999); Editorial Board of Prostaglandins, Leukotrienes and Essential Fatty 

Acids (1989-Present); Editorial Board of the Journal of Nutrition (2002-2004); Editorial Board 

of Chemistry and Physics of Lipids (2005-2008) 

• Ad hoc reviewer: American Journal of Physiology, Arteriosclerosis, Thrombosis and Vascular 

Biology, Archives of Biochemistry and Biophysics, Cancer Research, Carcinogenesis, Cell 

Growth and Differentiation, Clinical Chemistry, Free Radical Biology & Medicine, 

Gastroenterology, Journal of Biological Chemistry, Journal of Leukocyte Biology, Journal of 

Lipid Research, Journal of Nutrition, Journal of Nutritional Biochemistry, Lipids, Nutrition and 

Cancer, Oncogene, and Proceedings of the National Academy of Sciences. 

W. Les Dees, Professor 

• NIH Research Scientist Development Award (1987-92 and 1993-98) 

• Pfizer Research Award (1996) 

• TAMU Association of Former Students, Distinguished Achievement in Research (1996) 

• Carrington Laboratories Research Award (1989) 

• Grant Review Committees: NIH Alcohol and Toxicology III Study Section (1999-2003; NSF 

Integrative Biology and Neuroscience Subcommittee (1995-1998); NIH Special Emphasis 

Panels (1996-1997, 1999-2004); NIH NIAAA Center Review Subcommittee (2003); NIH 

Special Emphasis Panel for R-21 Grants (2004). 

K.C. Donnelly, Professor and Department Head 

• TAMU Biomedical Sciences Teaching Award (2001) 

• TAMU Dept. of Soil & Crop Sciences Superior Achievement Award for Technical Support 

(1988) 

• Environmental Mutagen Society Student Travel Award (1986) 

• Southwest Environmental Mutagen Society Outstanding Oral Presentation (1985, 1986) 

• Editorial Responsibilities: Environmental Toxicology and Chemistry, Environmental Science 

and Toxicology, Ecotoxicology and Environmental Safety, Journal of Toxicology and 

Environmental Health 

• Grant Review Committees: USEPA Star Grant (1997-1999); USEPA Reviewer for Health 

Assessment of PAH Mixtures 

John Fackler, Distinguished Professor 

• American Chemical Society Award for Distinguished Service to Inorganic Chemistry (2001) 

• Journal of Cluster Science, Volume 11, No. 1 dedicated in honor of 65 th Birthday (2000) 

• W. Manchot Forschungsprofessur, 1992, Munich, Germany, Anorganisch-Chemische Institut 

der Technischen Universität München (1992) 

• TAMU Development Council, College of Science, establishment of the John P. Fackler, Jr. 

Endowed Graduate Student Award (1991) 

• American Chemical Society Southwest Regional Award, American Chemical Society (1990) 

• ACS Morley Medal, Cleveland Section (1987) 

• Honoris Causa, Valparaiso University (1987) 

• Cleveland Technical Societies Council “Technical Achievement Award” (1971) 

• Professional and Honorary Societies: American Chemical Society (1956-present), American 

Crystallographic Association (1970-present), Royal Society of Chemistry (1960-present), 

Sigma Xi (1958-present), Fellow of the American Institute of Chemists (1988-present), 

American Association for the Advancement of Science (1963-present), Texas Academy of 

Science (1984-present), New York Academy of Science (1980-present), Pegasus Society

Robinson College, Cambridge (1992-present), Texas Alliance for Mathematics and Science 

Education (1985-present) 

• Editorial Responsibilities: Board of Directors, Inorganic Chemistry; Board of Editors, J. 

Cluster Science 

Richard Finnell, Professor and Executive Director 

• Regents Professor, Texas A&M University System Health Science Center (2005-present) 

• Teratology Society Wilson Publication Award (2000, 2004) 

• TAMU Association of Former Students Distinguished Achievement Award in Research 

(1997) 

• Pfizer Animal Health Award for Research Excellence (1995) 

• Cold Spring Harbor Summer Course Fellowship (1990) 

• March of Dimes Basil O’Connor Fellow (1982-1984) 

• Roche Foundation for Scientific Exchange Fellowship, Zürich, Switzerland (1981) 

• Outstanding Student Abstract Award - Int’l Congress Human Genetics, Montreal (1977) 

• Professional and Honorary Societies: American Board of Medical Genetics, diplomat 

(1982); American Society of Human Genetics; Teratology Society-National Council (1997- 

2001), Advisory Commission - Texas Birth Defects Monitoring Division; Vice-Chairperson 

(1995-1997), Chairperson (1997-present) 

• Editorial Boards: Teratology: Section Editor for Genetics and Cytogenetics (1992-1997); 

Molecular Genetics (1997-2000); Guest Referee Editor: American Journal of Medical 

Genetics; Associate Editor: Environmental Health Perspectives: Toxicogenomics (2002- 

2004); Associate Editor: Birth Defects Research: Clinical and Molecular Teratology; Chinese 

Journal of Reproductive Health 

• Ad hoc Reviewer: Science, Nature, Nature Genetics, Journal American Medical 

Association, Genomics, American Journal of Medical Genetics, Drug and Chemical 

Toxicology, Epilepsia, Proceedings of the National Academy of Sciences, The Journal of 

Neuroscience, Reproductive Toxicology, Birth Defects Research, The Medical Letter, 

Pediatric Research, Society for Experimental Biology and Medicine, Fundamental and 

Applied Toxicology, Journal of Obstetrics and Gynecology, The Journal of Experimental 

Zoology, Analytical Biochemistry, American Journal of Clinical Nutrition, Obstetrics and 

Gynecology, Journal of Clinical Investigation, Journal of Toxicology and Environmental 

Health, Experimental Cell Research, In Vitro Cellular and Developmental Biology, Molecular 

Genetics and Metabolism, Clinical Genetics, European Journal of Human and Clinical 

Genetics, The FASEB Journal, Toxicological Sciences, Human Molecular Genetics, J. 

Pharmacology Science and Physical Therapy, International Journal of Developmental 

Biology, Nature Reviews-Genetics, Am. J. Physiology, Pediatrics, Developmental Brain 

Research, Human Reproduction 

• Grant Review Committees: Public Health Service; Standing Member, Oral Biology and 

Medicine Study Section-OBM I (1991-1995); NIH Reviewer’s Reserve (1995-present); 

Medical Research Council of Canada; Medical Research Council- United Kingdom; USDA 

National Research Initiative Competitive Grants Program; Veterans Administration Medical 

Research Service; Air Force Office of Scientific Research; March of Dimes - Birth Defects 

Foundation; National Science Foundation WellBeing Foundation and The Wellcome Trust; 

The Netherlands Organization for Health Research and Development; Israel Science 

Foundation 

• Scientific Advisory Panels: World Health Organization Technical Consultation on 

Craniofacial Malformations (2000); University of Wisconsin Environmental Health Sciences 

Center for Developmental and Molecular Toxicology (2001-2005); University of Florida 

School of Medicine-Fetal Antiepileptic Drug Neurodevelopment Program (2000-present);

Duke University Environmental Health Sciences Center for Comparative Biology of 

Vulnerable Populations (2002-present); International League Against Epilepsy Commission 

on Genetics (2003-present); EURAP Congenital Malformation Registry. Scientific Advisory 

Board (2002-present); Case Western Reserve University Fetal and Environmental 

Exposures Training Grant. Scientific Advisory Board (2005-present); American Academy of 

Neurology Practice Parameter for the Management of Women with Epilepsy. Committee 

member (2005-present); World Health Organization Technical Consultation on Folate and 

Vitamin B12 Deficiencies (2005); University of Texas San Antonio Biology Program Scientific 

Advisory Board (2006-present) 

Roger B. Harvey, Veterinary Medical Officer 

• Distinguished Scientist, American Men and Women of Science, (1994-95) 

• Early Career Scientist of the Year, U.S.D.A., Southern Plains Area (1991) 

• Daniel E. Salmon, Federal Veterinarian of the Year Award (1991) 

• Engelhard Corporation Award of Merit for Research on NovaSil (1989) 

• Professional and Honorary Societies: American Veterinary Medical Assoc., American Assoc. 

of Swine Practitioners, American Assoc. of Avian Pathologists (AAAP), American Assoc. of 

Veterinary Laboratory Diagnosticians (AAVLD), American Academy of Veterinary and 

Comparative Toxicology (AAVCT), U.S. Animal Health Assoc., World Veterinary Poultry 

Assoc., World Veterinary Medical Assoc., Society Experimental Biology and Medicine 

• Scientific Advisory Panels: Chair, Toxic and Miscellaneous Infectious Diseases Committee, 

AAAP (1991-1994); Food Safety Committee, AAAP (1994-1997); Animal Care and Use 

Committee, Food Animal Protection Research Lab (1990-1996); Controlled Substances 

Officer, SPARC (1993-present); Salmonella Working Group, National Pork Board (1998- 

present) 

• Salmonella Intervention Committee, National Pork Board (1998-present); NAPES 

Committee, National Pork Board (2002-present); Executive Council, AACVT (1992-1995) 

• Editorial Boards: Section Editor: Mycotoxins and Natural Toxins, Quintessence (1994-1995); 

Reviewer: Pre-Harvest Food Safety Research Proposals, National Pork Board (1999- 

present); Reviewer: Research Proposals, Food Safety, NRI, USDA-CSREES (1998- 

present); Editorial Review Board, Food Additives and Contaminants (2000-present) 

Larry Johnson, Professor 

• Texas A&M University Chapter of Sigma Xi Science Communication Award (2001) 

• CVM Biomedical Science Undergraduate Program Teaching Award (1999) 

• TAMU Honors Undergraduate Program Teaching Award (1996) 

• Research Career Development Award (1991-1996) 

• American Society of Andrology’s Young Andrologist Award (1988) 

• NIH New Investigator Research Award (1983-1986) 

• Editorial Boards: Biology of Reproduction (1989-1995), AGE (1992-1995), Journal of 

Andrology (1997-present) 

Ann Kier, Professor 

• Women’s Progress: Texas A&M University Administrator Award (2004) 

• Rhodes Faculty Abroad Program with Mexico (2002) 

• American Men and Women in Science (1982, 1994, 1997) 

• Scientific Review Evaluation Award, NIH, National Center for Research Resources (1994-1996) 

• NIH Post Doctoral Fellowship in Laboratory Animal Medicine, Univ. of Missouri (1976-1979)

• Editorial Boards: Journal of Comparative Medicine (Editorial Board, 1996-present); Journal of 

The American Veterinary Medical Association; American Journal of Veterinary Medical 

Research; Veterinary Pathology; Journal of Protozoology; Journal of Comparative Pathology; 

Veterinary Immunology and Immunopathology; W. B. Saunders, Churchill Livingstone, 

Academic Press; Editorial Advisory Board, Advances in Veterinary Science and Comparative 

Medicine (1995-present) 

• Grant Review Committees: Ad Hoc Study Section, NIH Allergy and Infectious Diseases 

Institute (1984); Ad Hoc Study Section, NIH General Medical Sciences Institute (1985-1986, 

1989, 1991); Ad Hoc Study Section, NCI (1986); Ad Hoc Study Section, NIH National Institute 

of Child Health and Human Development (1987); Immunobiology Contract Review Study 

Section, NIH, National Cancer Institute (1986-1988); Ad Hoc Study Section, NIH Division of 

Research Resources (1988-1990); Ad Hoc, Board of Scientific Councilors, NIH, National 

Center for Research Resources Review, Diagnostic Services (1995-1996); Chairman, Ad Hoc 

Study Section, NIH, National Center for Research Resources (1996); Comparative Medicine 

Study Section, NIH National Center for Research Resources (1992-1996); Howard Hughes 

Medical Institute Program, Applications from new investigators, Office of the Vice President for 

Research, Texas A&M University (1996); Chairman, Ad Hoc Study Section, NIH National 

Center for Research Resources (1997); Chairman, Ad Hoc Study Section, NIH National Center 

for Research Resources, RFA, Mutant Mouse Regional Resource Centers (1999); Ad Hoc 

Study Section, NIH National Center for Research Resources, T32 review (1999); Ad Hoc Study 

Section, NIH National Institute of Environmental Health Sciences, Mouse Mutagenesis 

Resource Centers (2000); External Advisory Committee, University of Cincinnati Medical 

Center, Center for Environmental Health, Peter Stambrook, Principal Investigator (2001- 

present); Ad Hoc Study Section, NIH National Center for Research Resources, Mouse Mutant 

Resource Centers (2003-2005); Ad Hoc Study Section, NIH National Institute of Environmental 

Health Sciences, Toxicology Resource Centers (2004); Ad Hoc Contract Review, NIH National 

Institute of Environmental Health Sciences (2004); Ad Hoc PO1 Study Section Review, NIH 

National Institute of Environmental Health Sciences review (2005) 

Gladys Ko, Assistant Professor 

• NIH Individual National Research Service Award (2001-2004) 

• NIH Training Grant, Neurobiology & Anatomy, Univ. of Texas Medical School (1997-1999) 

• T.C. Yin, MD Memorial Scholarship, National Yang-Ming Medical College, Taiwan (1991) 

• Annual Scientific Research Award, National Cheng-Kung University, Taiwan (1989) 

• Professional and Honorary Societies: Association for Research in Vision and 

Ophthalmology (2005-current), Society for Neuroscience (1990-current), Association of 

Anatomists of R.O.C. (1989-1992) 

Rajesh Miranda, Associate Professor 

• Grant Review Committees: Ad-hoc reviewer, NIH, ALTX-3 study section.( 2002-2003); Adhoc 

reviewer, NIH, NAL (Neurotoxicology and Alcohol) study section (2003); Member, NIH, 

NAL (Neurotoxicology and Alcohol) study section (2004-2007); Ad. Hoc. member of NIH AA- 

1 Biomedical Research Review Subcommittee (2006) 

Philip Mirkes, Professor and Director 

• Fogarty Senior International Fellow, Experimental Embryology and Teratology Unit Medical 

Research Council, London, England, Host: Dr. Nigel Brown (1988-1989) 

• Warkany Lecturer, 41 st Annual Meeting of the Teratology Society (2001) 

• Professional and Honorary Societies: American Association for the Advancement of 

Science, Teratology Society: Past President (1998-1999), President, Teratology Society

(1997-1998), Vice President, (1996-1997), Chairperson, ad hoc committee on grant funding 

(1995-1996), Education Committee (1994-1996), Secretary (1995), Public Affairs Committee 

(1992-1994), Chairperson, Strategic Planning Committee (1996-current), Vice Presidentelect 

(1995-1996), Chairperson, Nominations and Elections committee (1990- 

1991),.Chairperson, Constitution and Bylaws committee (1990-1991),.Chairperson, 

Symposium on Hyperthermia and Teratogenesis (1986) 

• Editorial Boards: Editor, Birth Defects Research (A): Clinical and Molecular Teratology 

(2003-current); Associate Editor, Toxicology and Applied Pharmacology (2002-current); 

Member, Editorial Advisory Board, Toxicology and Applied Toxicology (1996-current) 

• Grant Review Committees: Member, NIH Biology of Development and Aging Study Section 

Boundaries Team (2001); Member, NIEHS Center Site Visit Team, University of Wisconsin 

(2001); Member, NIEHS Program Project Site Visit, University of Michigan (2001);Member, 

National Institutes of Health - Human Embryology Study Section (HED-2, 1992-1996); 

Member, March of Dimes Grant Review Committee - Reproductive Hazards in the 

Workplace, Home, Community and Environment (1985-1992) 

• Scientific Advisory Panels: National Children’s Study-Birth Defects Working Group (2002); 

International Life Science Institute Health and Environmental Sciences Institute (HESI) On 

vitro Assays Workshop Planning Committee (2005-current); International Life Science 

Institute (ILSI) Risk Science Institute Committee on Developmental Toxicity Data and SAR 

Model Development (2004-current); NICHD Symposium entitled: 1 st NIH Structural Birth 

Defects Investigators Meeting (2001); National Academy of Sciences/National Research 

Council Committee on Developmental Toxicology (1997-2000); NICHD Working Group on 

Birth Defects (1996-1999); NIEHS-sponsored Workshop entitled: Signal Transduction 

Grantee Meeting (2001); Chair, NICHD Special Emphasis Panel Review for RFA HD-99-008 

“Developmental Mechanisms of Human Malformations (2000); NICHD Birth Defects 

Organizing Committee (1996); NIEHS sponsored Series of Workshops on Molecular and 

Cellular Mechanisms of Early Mammalian Development (1992-1993); NIEHS committee to 

draft a new list of teratogens and non-teratogens for the validation of in vitro screens (1990- 

present); Martin Marietta and Oak Ridge - Analysis of developmental toxicity of chemicals 

based upon literature reviews (1985-present) 

Miguel Mora, Adjunct Professor 

• US Geological Survey Star Award (2003, 2005) 


Science, American Ornithologists Union, Colonial Watebirds Society, Cooper Ornithological 

Society, SACNAS, Sigma Xi, Society of Environmental Toxicology and Chemistry, 

Southwestern Association of Naturalists, The Wildlife Society 

Jack Nation, Professor 

• Murray and Celeste Faskin Chair in Distinguished Teaching (2005-present) 

• Distinguished Research Award in the College of Liberal Arts (2004) 

• University Undergraduate Research Fellow (2003) 

• Ralph R. Thomas ’21 Professorship in Liberal Arts (2001-present) 

• Fellow, College of Liberal Arts Faculty, Texas A&M University (2000-2002) 

• TAMU Association of Former Students Distinguished Achievement Award in Teaching (1995) 


• National Review Panel: NIH National Institute on Drug Abuse, Edge Basic Research 

Awards (CEBRA), ZDA1 TXLQ10, Office of Extramural Research (2001-2004) 

• Editorial Board: Archives of Clinical Neuropsychology

• Ad Hoc Reviewer: National Science Foundation, Canadian Psychological Review, Journal 

of Applied Behavior Analysis, Journal of Abnormal Psychology, Journal of Personality and 

Social Psychology, Learning and Motivation, Animal Learning & Behavior, Science 

• Ad Hoc Editorial Consultant: Journal of Experimental Psychology: General, American 

Journal of Psychology, Neurotoxicology and Teratology, Neurotoxicology, Psychological 

Bulletin, Experimental and Clinical Psychopharmacology, Behavioral Brain Research, 

Psychopharmacology, Pharmacology, Biochemistry, and Behavior, Behavioral 

Pharmacology 

• Professional and Honorary Societies: Southwestern Psychological Association, The 

Psychonomic Society, Neurobehavioral Toxicology Society, Research Society on Alcoholism, 


Alan Parrish, Associate Professor 

• Recognition Award for Meritorious Research by a Young Investigator, The American 

Physiological Society Renal Section (2004) 

• Distinguished Teaching Award, College of Medicine, Texas A&M Health Science Ctr. (2003) 

• Colgate-Palmolive Post-Doctoral In Vitro Toxicology Fellowship, Society of Toxicology (1997) 

• Carl Smith Award for Outstanding Student Research in Mechanisms of Toxicity, SOT (1996) 

• TAMU George T. Edds Outstanding Toxicology Student, College of Vet. Medicine (1996) 

• Professional and Honorary Societies: American Physiological Society, American Society of 

Nephrology, American Society for Pharmacology and Experimental Therapeutics. 

• Editorial Board: Cell Biology and Toxicology (2001- ), Toxicology Letters (2003- ), Journal of 

Ocular Pharmacology and Therapeutics (2003-2004). 

• Ad hoc Reviewer: Toxicology In Vitro, Life Sciences, In Vitro Cellular and Developmental 

Biology, Cell Biology and Toxicology, Toxicology and Applied Pharmacology, Toxicology 

Letters, Toxicological Sciences, Journal of Ocular Pharmacology and Therapeutics, British 

Journal of Pharmacology, Journal of Vascular Research, Environmental Health 

Perspectives: Toxicogenomics, American Journal of Physiology: Renal Physiology, 

Biochemical Pharmacology, Journal of Molecular Histology, International Journal of 

Pharmaceutics, Mechanisms of Ageing and Development, Journal of Pharmacology and 

Experimental Therapeutics, Biochimica et Biophysica Acta 

• Grant Review Committees: NIH/NCI SRBB-U Special Emphasis Panel, Innovative Models 

in Toxicology (2003-2004); Oklahoma Center for the Advancement of Science and 

Technology; Oklahoma Health Research Program (2006); Toxicology Excellence for Risk 

Assessment (TERA); panel member for the toxicological review of acrylonitrile (2003) 

Timothy Phillips, Professor 

• TAMU Association of Former Students Distinguished Research Achievement Award (1988, 

2006) 

• Expert Panel on Aflatoxins, CDC/WHO, Geneva, Switzerland (2005) 

• Invited Speaker, World Mycotoxin Forum, European Commission, Amsterdam (2005) 

• Invited Speaker, The World Food Prize, Des Moines, IA (2005) 

• Bush Award for Excellence in International Research (2005) 

• Sigma Xi Distinguished Scientist Award, TAMU (2003) 

• Keynote Address, Pan American Symposium on Mycotoxins, Mexico City (2003) 

• BIFAD Chair’s Award for Scientific Excellence, Capitol Hill, Washington DC (2002) 

• Faculty Fellow, Texas Agricultural Experiment Station (2002) 

• Invention Disclosure: Matrix-Immobilized adsorbents (1999) 

• Pfizer Award for Excellence in Research (1998)

• Chair, TAMU Interdisciplinary Faculty of Toxicology (1996-1998, 2002-2004) 

• Board of Scientific Advisors, American Council on Science and Health (1986-present) 

• Invention Disclosure: Equilibrium Adsorption of Zearalenone by Organophilic Clay (1997) 

• Technology License Agreement: VICAM, Watertown, MA (1995) 

• SmithKline Beecham Award for Research (1993) 

• Committee on Agriculture, U.S. House of Representatives, CAST report (1990) 

• Engelhard Achievement Award for the Discovery of Novasil TM (1989) 

• Council for Agricultural Science and Technology (CAST) Task Force (1988) 

• President, Gulf Coast Chapter, Society of Toxicology (1986-1987) 

• Texas A&M University System Award in Research (1986) 

• Faculty Achievement Award in Research, Texas Veterinary Medical Association (1985) 

• Chairman, USDA S-175 Technical Committee on Mycotoxins (1984-1985) 

• Advisory Panel, National Space Technology Laboratories (1984-1986) 

• International Program Activities (USAID), Senegal, West Africa (1983-1996) 

• Secretary/Treasurer, USDA S-132 Technical Committee on Mycotoxins (1982-1983) 

• Robert A. Welch Foundation Postdoctoral Fellowship (1975-1976) 

• National Defense and Education Act Predoctoral Fellowship (1971-1975) 

• Editorial Boards: Co-Editor, Food Additives & Contaminants, Taylor & Francis, Oxfordshire, 

U.K. (2003-present); International Editorial Board for “Food Additives & Contaminants”: 

London, England, (2001); Editorial Board, "Environmental Toxin Reviews", 1984-1996 

• Grant Review and Scientific Advisory Committees: USDA NRICGP Study Panel on Animal 

Health (1998), Scientific Advisory Panel, Ralston Purina International, St. Louis, Missouri 

(1992), Analytical Separations Advisory Council, Waters Associates, Inc. (1984) 

• Professional and Honorary Societies: Society of Toxicology, Specialty Section on Food 

Safety, Nominating Committee (1982-83); American Chemical Society; Specialty Section on 

Chemical Toxicology 

Patricia Pietrantonio, Associate Professor 

• Sloan Foundation Scholar (2006) 

• Texas Agricultural Experiment Station Fellow (2006) 

• TAMU Executive Vice President and Provost’s Diversity Award (2004) 

• TAMU Agriculture Program Vice Chancellor’s Award for Excellence in Research (2003) 

• DuPont Young Professor Grant (2001) 

• Most Cited Article published by the Annual Review of Entomology as of June 5, 2001: Gill, 

SS, EA Cowles and PV Pietrantonio. 1992. “The mode of action of Bacillus thuringiensis 

endotoxins.” Annu. Rev. Entomol. 37: 615-36 (2001) 

• 1998-99 Montague Center for Teaching Excellence Scholars Award for Excellence in 

Undergraduate Education, College of Agriculture and Life Sciences, TAMU (1999) 

• Henry Comstock Outstanding Graduate Student Award, Entomological Society of America 

(1994) 

• Academic Excellence Award, Dept. of Entomology, University of California, Riverside (1994) 

• Rotary International Foundation Freedom from Hunger Competitive Scholarship, University 

of California, Riverside (1987-1990) 

• Best Student Scholarship, American-Argentine Cultural Institute, Buenos Aires, Argentina 

(1986-1987) 

• INTA Research Fellowship, National Competitive Award. Plant Protection Department, 

National Institute for Agriculture and Cattle Technology Castelar, Argentina (1983-1985) 

• Editorial Boards: Reviewer for 2 NRI/USDA proposals on Gateways to Genomics. (2005); 

Reviewer for 2 NRICGP/USDA proposals on Functional Genomics (2003);

Entomology/Nematology proposal review panel (Suborganismal) NRI/USDA (2002); 

Entomology/Nematology proposal review panel (Organismal) NRI/USDA (1998) 

• Grant Review and Scientific Advisory Committees: National Research Council 

Associateship Programs (Post-doctoral), and graduate fellowship program review, Ford 

Foundation (2001); Predoctoral, Dissertation and Postdoctoral Fellowships for Minorities, the 

Howard Hughes Medical Institute Predoctoral Fellowships in Biological Sciences and the 

NASA Administrator's Fellowships (2000) 

• Ad-Hoc reviewer: National Science Foundation (NSF) Endocrinology Panel (2001); National 

Research Initiative - U.S. Department of Agriculture (NRI/USDA). Entomology/Nematology 

Suborganismal Panel (2001); NRI/USDA Entomology/Nematology Panel (2000) 

Suresh Pillai, Professor 

• Assoc. Director of Research, Institute of Food Science & Engineering, TAMU (2000-2005) 

• Chair, Professional Program in Biotechnology, TAMU (2004-present) 

• Director, National Center for E-Beam Food Research, TAMU (2003-present) 

Weston Porter, Assistant Professor 

• Susan G. Komen Breast Cancer Foundation Postdoctoral Fellowship (1999-2001) 

• Texas A&M Association of Former Students - Distinguished Graduate Student Award (1998) 

• Society of Toxicology Graduate Student Fellowship-Procter and Gamble Award (1996) 

• George T. Edds Toxicology Outstanding Graduate Student Award (1995) 

• NIEHS Predoctoral Training Grant Fellowship, TAMU (1992-1996) 

• Grant Review Committees: Department of Energy, External Advisory Board, Lawrence 

Livermore National Laboratories Center for Accelerator Mass Spectrometry (2003) 

• Ad Hoc Reviewer: Molecular and Cellular Endocrinology, Toxicology, Molecular 

Endocrinology, TAP. Biology of Reproduction 

Shashi Ramaiah, Assistant Professor 

• Completed GLP training for Nonclinical Laboratory Studies (2006) 

• Chair, Continuing Education Committee, Society of Toxicologic Pathology (2006) 

• Elected Secretary of the Gulf Coast Chapter of the Society of Toxicology (2006) 

• C. L. Davis Award (University of Florida), ACVP Annual Meeting (2002) 

• Young Investigator Award Poster Competition, ACVP Annual Meeting (2001) 

• Young Investigator Award in Experimental Disease, ACVP Annual Meeting (2000) 

• Excellence in Research Award, School of Pharmacy, Univ. of Louisiana at Monroe (1999) 

• Best Research Award, Division of Toxicology, University of Louisiana at Monroe (1999) 

• Best Paper published in Toxicology and Applied Pharmacology, Society of Toxicology (1999) 

• Taylor and Francis, Best Paper Award in Food Safety Specialty Section, SOT (1999) 

• Best Paper, Academy of Toxicological Sciences, American College of Toxicology (1998) 

• Best Paper at the Risk Assessment Specialty Section, SOT (1998) 

• Young Investigator Award from the SCC-Society of Toxicology (1997) 

• George Bacon Scholarship from the Louisiana Cancer Registry (1997) 

• Academy of Toxicological Sciences Fellowship for Best Paper, American College of 

Toxicology (1997) 

• University resident Merit Scholarship, Veterinary College, UAS, India (1993) 

• Merit Scholarship from Karnataka State Teachers benefit fund, India (1987) 

• Professional and Honorary Societies: Society of Toxicology (1996-Present), American 

College of Toxicology (1996-Present), Society of Toxicologic Pathology (2004-Present), 

American Society for Veterinary Clinical pathology (1999-Present), American Association for

the Study of Liver Diseases (2002-2004), American College of Veterinary Pathologists 

(2002-Present), American Veterinary Medical Association (2003-Present), Texas Research 

Society on Alcoholism (2003-Present), American Association for Investigative Pathology 

(2005-Present) 

• Editorial Boards: International Journal of Toxicology (2002-Present); Editorial Board 

Member: Veterinary Clinical Pathology (2005-Present) 

• Ad Hoc Reviewer: Hepatology, International Journal of Toxicology, Journal of Pathology, 

Journal of American Veterinary Medical Association, Veterinary Clinical Pathology, 

Toxicological Sciences, American Journal of Veterinary Research 

Frank M. Raushel, Professor 

• Davidson Professor of Science (2004) 

• 18 th Enzyme Mechanisms Conference, Chair (2003) 


(2000) 

• NIH Research Career Development Award (1985-1990) 

• NIH New Investigator Research Award (1982-1984) 

• NIH Postdoctoral Fellowship (1978) 

• Gulf Oil Fellowship, University of Wisconsin (1974) 

• Wharton Fellowship, University of Wisconsin (1973) 

• Grant Review and Scientific Advisory Committees: German Research Foundation (DFG) 

Review Panel on Directed Evolution to Optimize and Understand Biocatalysis (2004-2008); 

Reactive Surfaces Ltd., consultant (2002-2004); Gilead Sciences, consultant (2002-2003); 

NIH NIGMS, ad hoc council member (2002); NIH Physical Biochemistry Study Section, ad 

hoc member(2002); Dupont Pharmaceuticals, consultant (1999-2001); Albemarle 

Corporation, consultant (1999-2000); NIH Biochemistry Study Section (1995-1999); NIH 

Biomedical Science Study Section-member (1989-1993) 

• Editorial Boards: Archives of Biochemistry & Biophysics (2005-2008), Biochemistry (2000- 

2008), Bioorganic Chemistry (1998) 

• Professional and Honorary Societies: Protein Society, American Society of Biochemistry 

and Molecular Biology (1982), American Chemical Society (Executive Committee 2002- 

2004), American Association for the Advancement of Science 

John Reagor, Professor 

• Special Achievement Award, Texas Sheep and Goat Raisers (2002) 

• Vice Chancellor’s Award in Excellence (1999) 

• Regents Fellow (1998) 

• Faculty Achievement Award, TVMA (1998) 

• Award of Special Merit Distinguished Service Award, TVMA (1995) 

• Award of Special Merit Distinguished Service Award, TVMA (1986) 

• Deputy Chancellor’s Distinguished Performance Award (1984) 

• Honorary Member Texas Veterinary Medical Association (1973) 

Leon H. Russell, Professor 

• Keynote Speaker, World Veterinary Day, Taiwan (2006) 

• AVMA President’s Award (2006) 

• Southwest Veterinary Symposium Award for World Leadership in Veterinary Medicine (2005) 

• Plenary Lecture, Veterinary Public Health Congress in Brazil (2005) 

• Plenary Speaker, 13 th Congress of Chile Veterinary Medicine, Univ. of Austral, Chile (2004)

• XIIth International Veterinary Congress Prize (2000) 

• Appointed by the U.S. Secretary of Agriculture to the National Advisory Committee on 

Microbiological Criteria (1999-2001) 

• “B.G. Russell McNellis Memorial Guest Lecturer” at the 49th International Military Veterinary 

Medicine Symposium, Chiemsee, Germany (1998) 

• Appointed to the Texas Department of Health’s Committee on Bioterrorism (1998-1999) 

• Distinguished Membership, Texas Veterinary Medical Association (1998) 

• Helwig-Jennings Award (1998) 

• Appointed to the Texas Committee on Transmissible Spongiform Encephalopathies by Texas 

Department of Health (1997) 

• U.S. Academic Representative, U.S. Delegation, U.S.-Indonesia Food and Agriculture 

Forum (1997) 

• Texas Veterinary Medical Association, President’s Award (1995) 

• Association of Military Surgeons of U.S., General James A. McCallam Award (1994) 

• El Paso, Texas, Mayor Larry Francis, Key to the City of El Paso (1994) 

• Commonwealth of Kentucky, Gov. B.C. Jones, Commissioned as Kentucky Colonel (1992) 

• Louisiana Veterinary Medical Association, Resolution of Recognition (1991) 

• American Veterinary Epidemiology Society, Honorary Diploma (1990) 

• TAMU Deputy Chancellor's Award for Excellence in Graduate Teaching (1990) 

• American College of Veterinary Preventive Medicine "Distinguished Diplomate" (1989) 

• Texas Veterinary Medical Association Faculty Achievement Award in Research (1988) 

• Alumnus of the Year, University of Missouri, College of Veterinary Medicine (1985) 

• Association of Teachers of Veterinary Public Health and Preventive Medicine of the United 

States and Canada, Award of Recognition (1984) 

• TAMU Association of Former Students Distinguished Achievement in Teaching (1982) 

• TAMU Association of Former Students Distinguished Achievement in Student Relationships 

(1979) 

• Norden Distinguished Teaching Award (1977) 

• Texas Veterinary Medical Association Faculty Achievement Award (1969) 

• Professional and Honorary Societies: Phi Tau Sigma, Gamma Sigma Delta, Phi Kappa Phi, 

Sigma Xi, Phi Zeta 

Stephen Safe, Distinguished Professor 

• Texas A&M Health Science Center Regents’ Professor (2006) 

• TAMU Association of Former Students Distinguished Research Achievement Award (2005) 

• JoAnn Treat Research Excellence Award, Texas A&M Research Foundation (2004) 

• Spirit of Innovation Award, Technology Licensing Office, Texas A&M University (2003) 

• Highly Cited Research in Pharmacology and Ecology/Environment, ISI, Thomson Scientific 

(2002) 

• High Impact Environmental Research – Environmental Science and Technology (2001) 

• McEwen Lecturer, Queen’s University (1998) 

• Honorary D.Sc., University of Guelph (1996) 

• Samuel H. Kuna Distinguished Lecturer, Rutgers University (1996) 

• Charles W. Gowdy Distinguished Lecturer, University of Western Ontario (1996) 

• Eli Lilly Science and Society Lecturer, Indiana State University (1995) 

• Distinguished Scientist Award, Sigma Xi, Texas A&M University (1995) 

• University Lecturer, Texas A&M University (1991) 

• MillerComm Lecturer, University of Illinois (1990)

• Burroughs Wellcome Toxicology Scholar (1989) 

• Distinguished Achievement Award for Research, Texas A&M University (1988) 

• Distinguished Lecturer, Toxicology Seminar Series, Univ. of Nebraska Medical School (1986) 

• Royal Society of Chemistry Award for Health, Safety or Environmental Chemistry (1984) 

• Queen's University Quest Lecturer (1980) 

• Queen's Silver Jubilee Medal (1978) 

• Sigma Xi Award for Excellence in Research (1977) 

• Commonwealth Scholarship (1963-1966) 

• NSERC Research Scholarship (1962) 

• Professional and Honorary Societies: Chemical Institute of Canada, Canadian Federation of 

Biological Societies, American Association for Cancer Research, American Society for Mass 

Spectrometry, American College of Toxicology, American Chemical Society, The Chemical 

Society, Canadian Society for Toxicology, Sigma Xi, International Society for the Study of 

Xenobiotics, Society of Toxicology 

• Editorial Responsibilities: Toxicology Editor, Chemosphere, Pergamon Press; Co-editor, 

Environmental Toxin Series, Springer Verlag Publishing Co.; Editorial Board, Toxicological 

and Environmental Chemistry, Gordon and Breach Science Publishers; Editorial Advisory 

Board, Journal of Biochemical and Molecular Toxicology, VCH Publishers Inc.; Advisory 

Board, Handbook of Environmental Chemistry, Springer Verlag Publishing Co.; Editorial 

Advisory Board, J. Women's Cancer; Editorial Advisory Board, J. Toxicol. Environ. Health; 

Editorial Advisory Board, Eur. J. Pharmacology; Associate Editor, Toxicological Sciences 

Friedhelm Schroeder, Professor 

• Charter Fellow, Michael E. DeBakey Institute of Comparative Cardiovascular Science and 

Biomedical Devices (2002) 

• Distinguished Achievement Award in Research, Texas A&M University (2001) 

• John A. Boezi Memorial Alumnus Award, Michigan StateUniversity (1995) 


(2001) 

• Div. Pharmacology and Medicinal Chemistry, Univ.of Cincinnati (1992) 

• Outstanding Researcher Award (1987-1992) 

• American Cancer Society Postdoctoral Fellowship (1974-76) 

• Phi Beta Kappa (1970); Sigma Xi (1972) 

• Phillips Medalist in Chemistry (1970) 

• University of Pittsburgh Scholarship (1966-70) 

• State of Pennsylvania Scholarship (1966-70) 

• Professional and Honorary Societies: American Society for Pharmacology and Experimental 

Therapeutics, American Society for Biochemistry & Molecular Biology, American Chemical 

Society, Biophysical Society 

• Editorial Boards: Associate Editor, Lipids (1983-present); Associate Editor, Protein 

Purification and Expression (1994-present); Associate Editor, Chemistry and Physics of 

Lipids (1995-2005); Associate Editor, Currents in Analytical Chemistry (2004-present) 

• Ad hoc Reviewer: J. Biological Chemistry, Biochemistry, Biochimica et Biophysica Acta, J. 

Biochemical & Biophysical Methods, J. Neurochemistry, Life Sciences, American J. 

Genetics, Science, Cancer Research, Molecular Pharmacology, J. Colloids & Surfaces, 

Atherosclerosis, J. Lipid Res., Neurobiol. of Aging, Circulation Research, Am. J. Reprod. 

Immunol. & Micro., Chemistry & Physics of Lipids., J. Pharm. & Exp. Ther., Biophys. J., J. 

Nutritional Biochem., Mol. And Cell. Path.,Proc. Natl. Acad. Sci. USA, Am. J. Nutr., Arch. 

Biochem. Biophys., Placenta, J. of Fluorescence, Hypertension, Circulation Research,

Histochemistry and Cell Biochemistry, Biochemistry and Cellular Biology, American J. of 

Nutrition, Oncogene, Life Sciences, Am. J. Vet. Res., Cell. Molec. Life Sciences 

• Grant Review Committees: Ad hoc Program Project Site Visitor for NIGMS, NCI, HLB, NIH 

(1984-present); Ad hoc grants reviewer for NIH; NIAAA; NSF; NCI; Hereditary Disease 

Foundation; VA; USDA; Israel Binational Science Foundation; NRC Canada; Wellcome 

Trust, Great Britain. (1982-present); NIH Reviewers Reserve, Metabolism Study Section. 

(1991-1998); NIH Special Emphasis Panel SSS-T (2000); Co-Chair, NIH Mouse Metabolic 

Phenotyping Center Study Section (2001); NIH Metabolism Study Section (1998-2001); NIH 

Special Emphasis Panel SSS-T(2001); NIH Special Emphasis Panel ZRG REN 01(2001); 

Chair, NIH Special Emphasis Panel ZRG1 SSS-T (02) (2001); Chair, NIH Special Emphasis 

Panel ZRG1 MET 02 (S) (2001); NSF Cell Biology Grant Review (2002); Chair, NIH Special 

Emphasis Panel ZRG F06 (20L) (2002-2004); NIH NIGMS Special Emphasis Panel ZGM1 

SIB-2(GG) “Large Scale Collaborative Project Awards” (2004); Chair, NIH Special Emphasis 

Panel ZDK GRB-9 (01) “Proteomics and Metabolomics in Type 1 Diabetes and its 

Complications” (2004); NIH Special Emphasis Panel ZRG1 CDF-2 (40) “Program Projects 

Review” (2004); Chair, Special Emphasis Panel ZRG1 F06 (20) “NRSA Applications” (2004); 

Ad hoc Reviewer for NSF “Experimental Physical Chemistry Program” (2005); NIH Special 

Emphasis Panel ZEB1 OSR-C (M1) “Roadmap Imaging Probes” (2005); Ad hoc Reviewer 

for Wellcome Trust (2005); NIH Special Emphasis Panel ZRG1 EMNR-B 02 M “Energy and 

Glucose Homeostasis” (2005); NIH Special Emphasis Panel ZDK1 GRB-9 (M1) “Mouse 

metabolic phenotyping centers” (2006); NIH Special Emphasis Panel ZRG1 EMNR-E (05) S 

(2006); Chair, NIH Special Emphasis Panel ZRG1 EMNR-B 02 S “Pancreatic beta cell 

development and function” (2006); NIH Special Emphasis Panel ZRG1 CVS-Q 02 S, 

“Nanomicroscopy in heart failure” (2006) 

Scott A. Senseman, Professor 

• CAPES Visiting Professor Fellowship, (Aug. 2005 - Feb. 2006) 

• Texas Cooperative Extension Superior Service Team Award (2005) 

• Team Finalist, Governor’s Award in Environmental Excellence for Atrazine Abatement (2005) 

• Outstanding Young Weed Scientist from Southern Weed Science Society (2003) 

• Outstanding Young Weed Scientist from Weed Science Society of America (2002) 

• TAMU Association of Former Students College Level Distinguished Teaching Award (2001) 

• Novartis Crop Protection Recognition Award in Agronomy (2000) 

• President, Texas Plant Protection Association (2000) 

• Vice President and Program Chair, Texas Plant Protection Association (1999) 

• TAMU Dept. of Soil and Crop Sciences Special Achievement Award for Teaching (1998) 

• Professional and Honorary Societies: Honorary Agricultural Fraternity Gamma Sigma Delta, 

Sigma Xi Scientific Research, Society, American Society of Agronomy, American Chemical 

Society, Weed Science Society of America, Southern Weed Science Society, International 

Weed Science Society, Texas Plant Protection Association. 

Michael Sherman, Associate Professor 

• TAMU Association of Former Students College Level Distinguished Achievement Award 

(2002) 

• Professional and Honorary Societies: American Statistical Association, Institute of 

Mathematical Statistics, President of the Texas Chapter of the American Statistical 

Association 

• Editorial Boards: Associate Editor, Journal of the American Statistical Association (2005- 

present); Associate Editor, Biometrics (1998-2000) 

• Grant Review Committees: Site Visit Team for the Carolina Population Center (2000)

• Ad Hoc Reviewer: Annals of the Institute of Statistical Mathematics, Annals of Statistics, 

Biometrics, Biometrical Journal, Communications in Statistics, Environmental and Ecological 

Statistics, Journal of the American Statistical Association, Journal of Computational 

Statistics and Data Analysis, Journal of Pediatric Oncology, Journal of the Royal Statistical 

Society, Journal of Statistical Planning and Inference, Mathematical Methods of Statistics, 

National Science Foundation, National Security Agency, Simulation, South African Research 

Foundation, State of Louisiana, Statistica Neerlandica, Statistics and Probability Letters 

Eric Simanek, Associate Professor 

• TAMU College of Science Montague-Center for Teaching Excellence Scholar (2003-04) 

• Innovation Award, Research Corporation (1999) 

• Eli Lilly Predoctoral Fellowship, 1994-5, Harvard University (1994-95) 

• Distinguished Teaching Award, Harvard University (1992) 

• Carl Shipp Marvel Research Award, University of Illinois (1991) 

• Outstanding Teaching Award, University of Illinois (1991) 

Thomas Spencer, Assistant Professor 

• Gordon Research Conference on Reproductive Systems Biology, Chair (2008) 

• Gordon Research Conference on Reproductive Tract Biology, Vice Chair (2006) 

• TAMU Agriculture Program Vice Chancellor’s Award in Excellence for Team Research 

(2005) 

• TAMU Agriculture Program Vice Chancellor’s Award in Excellence for Research (2005) 

• Sigma Xi Young Investigator Award (2005) 

• Society for the Study of Reproduction New Investigator Award (2004) 

• Australian Society for Reproductive Biology, Meat & Livestock Australia Plenary Lecturer 

(2004) 

• International Congress on Animal Reproduction-Young Scientist Designate from the Society 

for the Study of Reproduction (2004) 

• American Society of Animal Science Southern Section Outstanding Young Animal Scientist 

Award - Research (2003) 

• NIH National Research Service Award (1996) 

• TAMU Agriculture Program Vice Chancellor’s Award, Excellence for Graduate Research 

(1995) 

• Dr. A.M. “Tony” Sorenson, Jr. Achievement Award (1995) 

• Tom Slick Graduate Research Fellow (1994-95) 

• TAMU Regents’ Graduate Research Fellow (1992-94) 

• Auburn University Outstanding Graduate Student Award (1991) 


Science; American Society of Animal Science; Endocrine Society; Sigma Xi; Society for the 

Study of Reproduction and Fertility; Society for the Study of Reproduction (Education 

Committee, 1999-2002; Program Committee, 2002-2004; Public Affairs Committee- FASEB 

Science Policy Committee Representative, 2003-2006; Future Meetings Committee, 2006-); 

Texas Women’s Reproductive Health Consortium (Steering Committee, 2003-2005) 

• Editorial Boards: Biology of Reproduction (Associate Editor, 2005-present); American 

Journal of Reproductive Immunology (2006-present); Biology of Reproduction (2001-2005); 

BMC Reproductive Biology and Endocrinology (2003-2006); Domestic Animal Endocrinology 

(2002-2004); Reproduction (2004-present). 

• Ad hoc Reviewer: American Zoologist; Anatomical Record; Biology of Reproduction; BMC 

Reproductive Biology and Endocrinology; BMC Genetics; Canadian Journal of Physiology

and Pharmacology; Domestic Animal Endocrinology; Endocrine; Endocrinology; 

Experimental Cell Research; In Vitro Cellular and Developmental Biology-Animal; Journal of 

Anatomy; Journal of Animal Science; Journal of Biological Chemistry; Journal of Clinical 

Endocrinology and Metabolism; Journal of Endocrinology; Journal of Molecular 

Endocrinology; The Journal of Nutrition; Molecular Endocrinology; Preclinica; Reproduction; 

Reproduction, Fertility and Development. 

• Grant Review Committees: Binational Agriculture and Research Development Grants 

Program (2001-2004); Genome Canada (2005); Medical Research Council, United Kingdom 

(2005 and 2006); Horsetrack Betting and Levy Board, United Kingdom (2005 and 2006); 

NASA Developmental Biology Grants Program Panelist (2003); NIH Cellular Molecular 

Integrated Reproduction Study Section, Ad Hoc (2006); NIH Pregnancy and Neonatology 

Study Section, Ad Hoc Panelist (2005); NIH Specialized Cooperative Centers Program in 

Reproduction Research Study Section (2005); NIH OWRH Reviewer (2002); NSF Grants 

Program Reviewer (2002); The Lalor Foundation; The Wellcome Trust; USDA-National 

Research Initiative and Competitive Grants Program (Enhancing Animal Reproductive 

Efficiency 1997-2003, Panelist 2004 and 2006; Animal Genomic and Genetic Mechanisms 

2000-2002, Ad Hoc Reviewer) 

Clifford Spiegelman, Professor 

• Chance Lecturer, American Statistics Association (2005) 

• Statistics in Chemistry Award for best paper, joint award (2002) 

• Distinguished Achievement Award, ASA Section on the Environment (1994) 

• W.J. Youden Award, American Statistical Association (1991) 

• Professional and Honorary Societies: American Statistical Association, Institute of 

Mathematical Statistics, International Statistical Institute, Bernoulli Society, American 

Chemical Society, Society for Applied Spectroscopy, International Environmetrics Society, 

Consultant (title pending) to the Proteomics Program at the National Cancer Institute 

John Stallone, Associate Professor 

• Faculty Senate (Senator of College of Veterinary Medicine), TAMU (2005-present) 

• Pfizer Award for Research Excellence (2002) 

• Richard H. Davis Teaching Award, College of Veterinary Medicine, TAMU (2002) 

• Fellow, Michael E. DeBakey Institute of Comparative Cardiovascular Sciences, TAMU 

(2001-present) 

• Citation for Distinguished Service, American Journal of Physiology, Regul., Integ. and Comp. 

Section (2001) 

• NIH Individual NRSA Postdoctoral Fellowship (1986-1987) 

• NIH NRSA Postdoctoral Traineeship, Univ. of Tennessee (1984-1985) 

• Outstanding Dissertation Award, University of Arizona (1984) 

• University of Arizona Graduate Academic Scholarship (1983-1984) 

• Department of Energy-Associated Western Universities Graduate Fellowship (1976) 

• Dean's Honor List, San Diego State University (1971) 

• Professional and Honorary Societies: American Physiology Society (Chair, Animal Care and 

Experimentation Committee 1997-2000) 

• Grant Review and Scientific Advisory Committees: Ad Hoc Specialist (site visitor), 

Association for Assessment and Accreditation Laboratory Animal Care (1998-present); 

Research Peer Review Committee, American Heart Association, Western States Affiliate 

(2000-2003); Peer Review Consultant, NIH Reviewer Reserve, Cardiovascular 

Pharmacology and Physiology Sections (1993-1998)

• Editorial Boards: Amer. Journal of Physiology, Regul., Integr. Comp. Section (1998- 

present); Amer. Journal of Veterinary Research (2003-present) 

George Stoica, Professor 

• Texas A&M University Faculty Senate (2001) 

• Honorary Member of the University of Yassy-Romania (2001) 

• President of Phi Zeta Honor Society of Veterinary Medicine (1998) 

• Developmental Leave, IARC-Lyon, France (1997) 

• Professional and Honorary Societies: Phi Zeta, Phi Beta Delta 

• Ad hoc grant/manuscript reviewer for: Molecular Carcinogenesis, Journal of Veterinary 

Medical Association, Journal of Clinical & Experimental Metastases, Cancer Research, 

Biology of Reproduction, American Journal of Physiology: Heart and Circulatory Physiology 

• NIH Consultant and Reviewer 

James Thompson, Associate Professor 

• Wiley Distinguished Teaching Professorship, TAMU College of Vet. Medicine (1998-2001) 

• Merck, Sharp & Dohme Award for Teaching Innovation, TAMU College of Veterinary 

Medicine (1994) 

• Certifications/Licences: Diplomate, American College of Theriogenologists; Diplomate, 

American College of Veterinary Preventive Medicine (ACVPM) 

• Professional and Honorary Societies: Specialty group for Epidemiology in the ACVPM; 

American Veterinary Medical Association; American Statistical Association, Section on 

Bayesian Statistical Science, International Society for Veterinary Epidemiology and 

Economics, International Society for Environmental Epidemiology 

Yanan Tian, Assistant Professor 

• President-Elect, Gulf Coast Chapter, Society of Toxicology (2007) 

• Merck Predoctoral Fellowship (1988) 

• The New Jersey Cancer Research Award for Scientific Excellence (1997) 

• Professional and Honorary Societies: Society of Toxicology 

• Ad hoc Reviewer: Journal of Clinical Oncology, Environmental Health Perspectives, 

Toxicological Sciences, Chem Biol Interact, British Journal of Pharmacology and Drug 

Metabolism Reviews. 

• Grant Review and Scientific Advisory Committees: NIH, NIEHS, Program Project P01 (2005), 

XNDA study section (2004); Philip Morris External Research Program (2005); Alberta Heritage 

Foundation for Medical Research, Canada (2004) 

Evelyn Tiffany-Castiglioni, Professor 

• TestSmart Developmental Neurotoxicity Testing meeting, sponsored by Center for 

Alternatives to Animal Testing (CAAT), Johns Hopkins University, Invited plenary speaker 

(2006) 

• 5th International Conference on Early Toxicity Screening: Strategies and Approaches for 

Toxicity Screening in Drug Discovery and Development, Invited speaker (2005) 

• 10th Meeting of the International Neurotoxicology Association, Invited chair, symposium on 

“In Vitro Models and Biosensors for Detecting Neurotoxicity," Porvoo, Finland (2005) 

• International Society for Neurochemistry-European Society for Neurochem Congress, 

Invited chair, colloquium on “Astrocytes in Neurodegenerative Disease Processes,” 

Innsbruck, Austria (2005) 

• Professional and Honorary Societies: Society of Toxicology

• Editorial Boards: International Journal of Developmental Neuroscience (2000-present); 

Associate Editor, Neurotoxicology (2004-present) 

• Grant Review and Scientific Advisory Committees: NIOSH SOH Study Section (2003- 

present); NSF Graduate Fellowships Review Panel 2000-2002, 2005 

Nancy Turner, Associate Professor 

• TAMU Ethel Ashworth-Tsutsui Memorial Award for Mentoring (1998) 

• Certified Nutrition Specialist (1995) 

• Dan F. Jones Memorial Scholarship (1990) 

• Grant Review and Scientific Advisory Committees: Ad hoc reviewer, Georgian–US Bilateral 

Grants Program; member, proposal review panel for USDA NRI program Improving Human 

Nutrition for Optimal Health (2003, 2004); Secretary/Treasurer of the Diet & Cancer RIS of 

ASNS (2003-2005); Ad hoc reviewer for the National Medical Research Council (Singapore), 

(2003); Ad hoc reviewer, USDA NRI program on Bioactive Food Components for Optimal 

Health (2005); Jury member, ASN Excellence in Nutrition Education Award (2005); Chair, 

Postdoctoral proposal review committee for ASN (2006); Ad hoc member of the 

Chemo/Dietary Prevention study section, NIH (2006) 

• Professional and Honorary Societies: American Society for Nutritional Sciences, American 

Society of Animal Science, American Society for the Advancement of Science, The New 

York Academy of Sciences, Society for Experimental Biology and Medicine, Gamma Sigma 

Delta, Women's Faculty Network, American Physiological Society, American Association for 

Cancer Research, American Association of Cereal Chemists 

• Editorial Boards: Assistant to Journal of Nutrition Associate Editor (Dr. Joanne Lupton); Ad 

hoc reviewer for Bioresource Technology; Journal of Nutrition; Journal of Animal Science; 

Nutrition and Cancer; American Journal of Clinical Nutrition; Alcohol; and Biochimica et 

Biophysica Acta, Cancer Letters; Editorial Board, Journal of Animal Science (1999-2002); 

Associate Editor of ASNS Nutrition Notes (2000–present); co-Editor of special issue of 

Nutrition focusing on Nutrition in Space (2002) 

Cheryl Walker, Visiting Professor 

• Dallas/Fort Worth Living Legend Faculty Achievement Award in Basic Research (2006) 

• Austin and Mary Frances Bloch Lecture, University of Louisville School of Medicine (2006) 

• Keynote Address, Renal Toxicology and Toxicological Pathology International Symposium: 

Integration of Mechanistic Investigation and Morphological Evaluation, “Genetics Targets for 

Renal Carcinogenesis,” Lindau, Germany (2004) 

• Visiting Professor, Hunan Medical University, Cancer Institute, Peoples Republic of China 

(1993) 

• Board of Scientific Councilors, National Toxicology Program, NIEHS, NIH (2002-2005) 

• Grant Reviewer/Service on NIH/Other Study Sections: Small Business Innovation Research 

Concept Review Panel - Division of Extramural Research and Training NIEHS (1989-1990); 

Ad Hoc, Biological Models and Materials Resources Program Study Section, NIH (1990); 

Chair, Scientific Review Panels, Division of Extramural Research and Training, NIEHS(1991- 

1992); Ad Hoc, Carcinogenesis and Nutrition Study Section, American Cancer Society 

(1992); Ad Hoc, Pathology B Study Section, NIH (1993, 1998); Carcinogenesis and Nutrition 

Study Section, American Cancer Society (1994-1998; Member, Molecular Genetics - 2 Study 

Section, US Army, Breast Cancer Research Program, Department of Defense (1995-1997); 

Member, External Review Panel, Center for Bioenvironmental Research, Tulane University 

(1995-1998); Chairman, Molecular Genetics - 2 Study Section, US Army Breast Cancer 

Research Program, Department of Defense (1998, 1999); Member, NCI Study Section, 

Mouse Models of Human Disease Consortium (1999); Chairman, NIH Special Emphasis

Review Panel, NCI, NIH (1999); Reviewer, Dutch Cancer Society (1999); Member, 

University of California Tobacco-Related Disease Research Program Study Section (2001); 

Oncological Sciences Study Section, Boundary Setting Team, NIH (2001); Member, 

Tuberous Sclerosis and Neurofibromatosis Study Section, Department of Defense (2003); 

Member, Fetal Basis of Disease Special Emphasis Panel, NIEHS, NIH (2003); Member, 

Fetal Basis of Disease Study Section, NIEHS, NIH (2004); Ad Hoc, Clinical and Integrative 

Endocrinology and Reproduction (ICER) Study Section, NIH (2005); Member, California 

Tobacco-Related Disease Research Program (Cancer) Study Section (2006); Member, 

NIEHS Special Emphasis Panel (ONES award) ZES1 JAB-C, NIH (2006); Member, Special 

Emphasis Panel Interdisciplinary Partnerships in Environmental Health Sciences, ZRG1 

DIG-C, NIH (2006); Chairman, Site Visit Team, Laboratory of Carcinogenesis, NCI (2006); 

Ad Hoc Reviewer, Lung Injury, Repair, and Remodeling Study Section, Respiratory Sciences 

IRG, NIH (2006); Chairman, Molecular Biology and Genetics-2, Breast Cancer Research 

Program, Department of Defense (2006); Member, Scientific Review Panel, Kidney Disease, 

Department of Defense (2006); Reviewer, Tenovus Cancer Charity, Great Briton (2006) 

• Editorial Boards: Associate Editor, Carcinogenesis (1994-1996); Editorial Review Board, 

Environmental Health Perspectives, Senior Editor Toxicogenomics (1997-2005); 

Toxicological Sciences (1998-present); Associate Editor, Molecular Carcinogenesis (1992- 

present); Associate Editor, Cancer Research (1995-present); Senior Editor, Molecular 

Cancer Research (2002-present) 

• Professional and Honorary Societies: American Association for Cancer Research; Society 

of Toxicology; North Carolina Chapter, Society of Toxicology; Gulf Coast Chapter, Society of 

Toxicology; American Society for Cell Biology 

Naisyin Wang, Professor 

• Elected member, International Statistical Institute (2003) 


(2003) 

• TAMU University Faculty Fellow (2001-2005) 

• NIH FIRST Award (1997-2002) 

• Journal of American Statistical Association Editor's invited paper (1997) 

• Morse Woodbury research fellowship (1990-1991) 

• Sigma Xi research fellowship (1991) 

• Cornell Graduate School summer fellowships (1988-1991) 

• Ohio State University graduate fellowship (1986-1987) 

• Professional and Honorary Societies: Fellow, Institute of Mathematical Statistics; Elected 

member, International Statistical Institute; Phi Beta Kappa, Texas A&M Univerity Chapter; 

Fellow, American Statistical Association; Elected to the Phi-Tau-Phi Honor Society (Taiwan); 

International Biometrics Society (Regional Advisory Board 2001-2003); International 

Chinese Statistical Association (Public Relations Committee 1999-2002, Board of Directors 

2005-2007) 

• Editorial Responsibilities: Co-Editor, Biometrics (2006), Associate Editor (1997-2005); Co- 

Editor, Statistical Science (2005-2006); Associate Editor, Journal of the American Statistical 

Association (1999-2002, 2005-2006); Associate Editor, Communications in Statistics (1998- 

2001) 

• Grant Review Committees: NIH BMRD study section (2004-2008); NSF and NIH review 

panels (1999, 2001) 

James Wild, Professor 

• Research Fellow, TAMUS-Texas A&M University Agriculture Program (1999-2000)

• Fellow, American Academy for the Advancement of Science (1998) 

• Burton International Scholar, Texas A&M University (1994) 

• Outstanding Research Advisor, TAMU Undergraduate Honors Program (1992-93) 

• Outstanding Faculty Member in Genetics, TAMU Undergraduate Genetics Society (1993) 

• Regional Award for Teaching Excellence, Excellence in College and University Teaching, 

Southern Region (10 nation-wide awards), USDA Higher Education Program, National 

Association of State Universities and Land Grant Colleges (1993) 

• Outstanding Research Advisor in Biochemistry, University Honors Program (1991-92) 

• Master Teachers Council, TAMU College of Agriculture and Life Sciences (1992-present) 

• Outstanding Educational Partnership Program, "EARTHCARE in AFTERSCHOOL", Texas 

A&M University/Bryan Independent School District, Texas Statewide Award, Alliance for 

Science and Mathematics Education (1992-93) 

• Outstanding Professor in Biochemistry, TAMU Undergraduate Biochemistry Society (1982- 

83 and1990-91) 

• TAMU Association of Former Students College Level Distinguished Teaching Award (1988- 

1989) 

• Outstanding Faculty Award – TAMU Undergraduate Biochemistry Society (1986-1987) 

• TAMU Teacher/Scholar Award, University Honors Program (1986-1987) 

• TAMU Center for Teaching Excellence Incentive in Excellence Faculty Award (1985) 


• TAMU Outstanding Faculty Award, Teaching, Undergraduate Plant Sciences Society (1979) 

• U.S. Navy Achievement Award - Professional Activities, LT, MSC, USNR, Naval Medical 

Research Institute, Bethesda, MD (1975) 

• NIH Postdoctoral Fellow, University of California at Riverside (1972) 

• NSF Predoctoral Fellowship, University of California at Riverside (1970-1971) 

Cody Wilson, Master Toxicologist and Adjunct Associate Professor 

• Rear Admiral Charles S. Stephenson Award for Excellence in Preventive Medicine (2004) 

• Finalist, Rear Adml Charles S. Stephenson Award for Excellence in Preventive Medicine 

(2003) 

• US Navy Occupational Health & Preventive Medicine Workshop, 1st Place, Environmental 

Programs Poster (2002) 

• US Navy Occupational Health & Preventive Medicine Workshop, 1st Place, Occupational 

Health Research (2000) 

• Society of Toxicology, 1st Place, Molecular Biology Specialty Section Graduate Award 

(1997) 

• Michael Szabuniewicz Award in Toxicology, Texas A&M University (1996) 

• Certifications/Licenses: Diplomate, American Board of Toxicology (2001-present); Certified 

Hazardous Materials Manager (1999-present; recertified 2005) 

• Professional and Honorary Societies: Society of Toxicology (1999-present), SOT Task 

Force on Biological and Chemical Terrorism Preparedness (2002-2005); Society for Risk 

Analysis (2006–present) 

• Ad Hoc Reviewer: Toxicological Sciences and Journal of Toxicology and Environmental 

Health, Part B (2003 – present) 

• Grant Review Committees: Philip Morris External Research Program (2003–2005) 

Emily Wilson, Associate Professor 

• Charter Fellow, TAMU DeBakey Cardiovascular Research Institute for Comparative 

Cardiovascular Science and Biomedical Devices (2001-2007)

• College of Medicine Representative to the University Women’s Faculty Network (2003-2007) 

• Ad Hoc Reviewer: American Journal of Physiology: Cell Physiology, American Journal of 

Physiology: Heart and Circulatory Physiology, Biomechanics and Modeling in 

Mechanobiology, Cardiovascular Research, Circulation, Circulation Research, Experimental 

Biology and Medicine, Hypertension, In Vitro Cellular and Developmental Biology, Journal of 

Cellular Biochemistry, Journal of Vascular Research, Journal of Biological Chemistry, 

Proceedings of the National Academy of Sciences, Journal of Biomechanical Engineering 

• Grant Review and Scientific Advisory Committees: American Heart Association (Western 

Affiliates): 4A Atherosclerosis, Thrombosis and Vascular Wall Biology (2000-2003); Arizona 

Disease Control Commission (Ad Hoc) (1999-Present); National Institutes of Health 

Program Project Review: Mechanical Forces in Cardiovascular Cells (1999, 2000); Scott 

and White Research Initiative (1999); Texas A&M University Interdisciplinary Research 

Initiative (1998-1999); Life Science Task Force Initiative, Texas A&M University, 

(2001);NIEHS Program Project Review, Louisville KY, “Cardiovascular Toxicity of 

Environmental Aldehydes (2002); Center for Environmental and Rural Health, Pilot Project 

Grant Review Committee, Texas A&M University (1999-Present); Veterans Administration 

Merit Award (2001); U.S. Environmental Protection Agency Grants--Airborne Particulate 

Health Effects: Cardiovascular Mechanisms (2-G1) (2002); NIEHS Program Project Review, 

Research Triangle Park, NC, “Cardiovascular Toxicity of Environmental Aldehydes (2003); 

Ad Hoc reviewer, NIH Pathology A study section (2003); American Heart Association 

(Western Affiliates): 3B Cell & Basic Molecular Biology Cardiovascular Development, 

Immunology & Microbiology (2005, 2006); Grant Reviewer, American Heart Association, 

National, Vascular Wall Biology 1 Study Group (2005-2006); Grant Reviewer, NIH Program 

Project Review "Molecular determinants of vascular remodeling and angiogenesis". William 

Sessa, PI (2005-2006); NIH Special Emphasis Panel to review R21, R15 and R03 grants 

normally reviewed by AICS and VCMB study sections (2006) 

• Professional and Honorary Societies: American Association for Advancement of Science 

(1988-present), American Society of Cell Biology (1990-present), American Society of 

Biochemistry and Molecular Biology (1985-present), American Heart Association-- High 

Blood Pressure Council (1998-present), American Heart Association-Atherosclerosis, 

Thrombosis and Vascular Biology Council (1999-present), Microcirculation Society (2000- 

present), North American Vascular Biology Organization (2000-present)

Appendix J 

Faculty Biosketches

BIOGRAPHICAL SKETCH 

Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. 

Follow this format for each person. DO NOT EXCEED FOUR PAGES. 

NAME 

Burghardt, Robert C. 

eRA COMMONS USER NAME 

rburghardt 

POSITION TITLE 

Professor, Veterinary Integrative Biosciences, 


EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) 

INSTITUTION AND LOCATION 

DEGREE 

(if applicable) 

YEAR(s) 

FIELD OF STUDY 

University of Michigan, Ann Arbor, MI B.S. 1969 Zoology 

Wayne State University, Detroit, MI M.S. 1973 Biology 

Wayne State University, Detroit, MI Ph.D. 1976 Biology 

Harvard Medical School, Boston, MA Postdoc 1976-78 Reproductive Biology 

A. Positions and Honors 

1976 -1978 Ford Foundation Postdoctoral Fellow, Department of Anatomy and Laboratory of Human 

Reproduction and Reproductive Biology, Harvard Medical School 

1978 -1987 Assistant, Associate Professor, Department of Biology, Texas A&M University (TAMU) 

1982 -1987 Director, Electron Microscopy Center, TAMU 

1987 -1991 Associate Professor, Department of Veterinary Anatomy, TAMU 

1987 - Director, Image Analysis Laboratory, College of Veterinary Medicine, TAMU 

1991 - Professor, Department of Veterinary Integrative Biosciences, TAMU 

2005 - Chair, Faculty of Toxicology 

Texas A&M University Interdisciplinary Faculty Appointments: Faculty of Toxicology, 1991-present, Chair, 

2005-present; Faculty, Center for Animal Biotechnology and Genomics, Institute of Biosciences and 

Technology, 1992-present; Faculty of Reproductive Biology, 1995-present; Faculty of Biotechnology, 2001- 

present.; Associate Director, Center for Environmental and Rural Health, 2000-present 

Societies, Professional Activities, Honors & Awards: Societies: Society for the Study of Reproduction 

(SSR), Society of Toxicology. Professional Activities: Associate Editor, Biology of Reproduction, 1992-95; 

Editorial Boards, Cells Tissues Organs, 2004-; Journal of Applied Toxicology, 2006-; College of Vet. Medicine, 

Wiley Distinguished Teaching Professorship 2000-03; Associate Director, Center for Environmental and Rural 

Health; Associate Director, Superfund Basic Research Program Project; Chair, Publications Committee, SSR, 

1996-99, 2005-06; Chair, Awards Committee, SSR, 2004-05; Director, SSR, 2000-03; Ad hoc reviewer: 35 

different journals; Review committee service past 3 years: Ad hoc reviewer, NSF (Integrative Animal Biology, 

Signal Transduction and Regulation), NIH (temporary member, HED-1, 2002, 2004), NIEHS 2004, NIH/NIGMS 

MBRS 2004,USDA (Animal Reprod Efficiency), Wellcome Trust (Joint Infrastructure Fund, UK), Veterans 

Health Administration, Israel Science Foundation, Natural Sciences and Engineering Research Council of 

Canada, March of Dimes. Honors & Awards: Association of Former Students, Distinguished Teaching Award, 

1995;Vice Chancellor's Award in Excellence for Team Research in Uterine Biology and Pregnancy, 2005 

B. Selected Peer-Reviewed Publications In Past 3 Years (From 158 peer-reviewed publications) 

1. Gray CA, DL Adelson, FW Bazer, RC Burghardt, EN Meeusen, TE Spencer (2004) Discovery and 

characterization of a novel epithelial-specific galectin in endometrium that forms crystals in trophectoderm. 

Proc Natl Acad Sci USA 101:7982-7987. 

2. Li X, C Qin, R Burghardt, S Safe (2004) Hormonal regulation of lactate dehydrogenase-A through 

activation of protein kinase C pathways in MCF-7 breast cancer cells. Biochem Biophys Res Commun 

320:625-634. 

3. Spencer TE, RC Burghardt, GA Johnson, FW Bazer (2004) Conceptus signals for establishment and 

maintenance of pregnancy. Anim Reprod Sci 82-83:537-550. 

4. Joyce MM, FJ White, RC Burghardt, JJ Muniz, TE Spencer, FW Bazer, GA Johnson (2005) ISG15 

conjugates to cytosolic proteins during the peri-implantation period and is expressed at the uterineplacental 

interface throughout pregnancy in sheep. Endocrinology 146:675-684. 

5. Abdelrahim M, R Smith 3rd, R Burghardt, S Safe (2004) Role of Sp proteins in regulation of vascular 

endothelial growth factor expression and proliferation of pancreatic cancer cells. Cancer Res.64:6740-49.

6. Wu Q, R Burghardt, S Safe (2004) Vitamin D-interacting protein 205 (DRIP205) coactivation of estrogen 

receptor alpha (ERα) involves multiple domains of both proteins. J Biol Chem 279:53602-53612. 

7. Hayashi K, KD Carpenter, TH Welsh, Jr., RC Burghardt, LJ Spicer, TE Spencer (2005) The IGF system in 

the developing neonatal ovine uterus. Reproduction 129:337-347. 

8. Kim K, R Barhoumi, R Burghardt, S Safe (2005) Analysis of estrogen receptor α-SP1 interactions in breast 

cancer cells by fluorescence resonance energy transfer. Mol Endocrinol 19:843-854. 

9. Chintharlapalli S, R Burghardt, S Papineni, S Ramaiah, K Yoon, S Safe (2005) Activation of Nur77 by 

selected 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl) methanes induces apoptosis through nuclear pathways. 

J Biol Chem 280:24903-24914. 

10. Covington MD, KJ Bayless, RC Burghardt, GE Davis, AR Parrish (2005) Ischemia-Induced Cleavage of 

Cadherins in NRK Cells: Evidence for a Role of Metalloproteinases. Am J Physiol Renal 289:280-288. 

11. Jaeger LA, AK Spiegel, NH Ing, GA Johnson, FW Bazer, RC Burghardt (2005) Functional effects of 

transforming growth factor beta on adhesive properties of porcine trophectoderm. Endocrinol 146:3933-42. 

12. White FW, JW Ross, MM Joyce, RD Geisert, RC Burghardt, GA Johnson (2005) Steroid regulation of cell 

specific osteopontin expression in the pregnant porcine uterus. Biol Reprod 73:1294-1301. 

13. Zhang S, X Li, R Burghardt, R Smith 3rd, SH Safe (2005) Role of estrogen receptor (ER)α in insulin-like 

growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells. J Mol Endocrinol 35:433-447. 

14. Covington MD, RC Burghardt, AR Parrish (2005) Ischemia-induced cleavage of cadherins in NRK cells 

requires MT-1-MMP (MMP-14). Am J Physiol Renal Physiol, 290:F43-51. 

15. Gray CA, KA Dunlap, RC Burghardt, TE Spencer (2005) Galectin-15 in ovine uteroplacental tissues. 

Reproduction 130:231-240. 

16. Vanderlaag K, I Samudio, R Burghardt, R Barhoumi, S Safe (2005) Inhibition of breast cancer cell growth 

and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM. Cancer Lett 236:198- 

212. 

17. Abdelrahim M, E Ariazi, K Kim, S Khan, R Barhoumi, R Burghardt, S Liu, D Hill, R Finnell, B Wlodarczyk, 

VC Jordan, S Safe (2006) 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly 

activate estrogen receptor α. Cancer Res 66:2459-2467. 

18. Muñiz JJ, MM Joyce, JD Taylor II, JR Burghardt, RC Burghardt, GA Johnson (2006) Glycosylation 

dependent cell adhesion molecule 1 (GLYCAM-1) and L-selectin expression in sheep interplacentomal and 

placentomal endometrium. Reproduction 131:751-761. 

19. Barhoumi R, I Awooda, Y Mouneimne, S Safe, RC Burghardt (2006) Effects of benzo-a-pyrene on 

oxytocin-induced Ca 2+ oscillations in myometrial cells. Toxicol Lett 65:133-141 

20. Banerjee A, RC Burghardt, GA Johnson, FJ White, SK Ramaiah (2006) Potential role of osteopontin as a 

predictive biomarker in a rat model of alcoholic steatohepatitis. Toxicol Pathol, 34:373-384. 

21. Khan S, R Barhoumi, R Burghardt, S Liu, K Kim, S Safe (2006) Molecular mechanism of inhibitory aryl 

hydrocarbon receptor - estrogen receptor/Sp1 crosstalk in breast cancer cells. Mol Endocrinol. 20:2199-14. 

22. Willingham-Rocky LA, MC Golding, JM Wright, DC Kraemer, ME Westhusin, RC Burghardt (2007) Cloning 

of GJA1 (Connexin43) and its expression in canine ovarian follicles throughout the estrous cycle. Gene 

Expression Patterns. Gene Expression Patterns 7:66-71. 

23. Dunlap KA, M Palmarini, M Verela, RC Burghardt, K Hayashi, JL Farmer, TE Spencer (2006) Endogenous 

retroviruses regulate peri-implantation placental growth and differentiation. Proc Natl Acad Sci US A. 103: 

14390-14395. 

24. White FJ, RC Burghardt, J Hu, MM Joyce, TE Spencer, GA Johnson (2006) Secreted phosphoprotein 1 

(Osteopontin) is induced by estrogen in mouse uterine lumenal epithelium during conceptus attachment for 

implantation. Reproduction 132:919-929. 

25. Spencer TE, GA Johnson, FW Bazer, RC Burghardt, M Palmarini (2007) Pregnancy recognition and 

conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous 

retroviruses. Reprod Fertil Dev 19:65-78. 

26. Westhusin ME, T Shin, JW Templeton, RC Burghardt, LG Adams (2007) Rescuing valuable genomes by 

animal cloning: A case for natural disease resistance in cattle. J Anim Sci 85:138-142. 

27. Barhoumi R, RC Burghardt, Y Qian, E Tiffany-Castiglioni (2007) Effects of propofol on intracellular Ca(2+) 

homeostasis in human astrocytoma cells. Brain Res. Epub 2007 Feb 2. 

28. Spencer TE, FW Bazer, GA Johnson, M Palmarini, RC Burghardt (2007) Fetal-maternal interactions during 

the establishment of pregnancy in ruminants. Reproduction (Suppl), in press.




NAME 

Phillips, Timothy D. 


tdphillips47 


Professor 



DEGREE 


YEAR(s) 


Mississippi State University B.S. 1970 Gen. Sci./Chemistry 

University of Southern Mississippi M.S. 1972 Chemistry/Sci. Ed. 

University of Southern Mississippi Ph.D. 1975 Chemistry 

A. POSITIONS AND HONORS 

Professional Experience 

1990 - present: Professor; Intercollegiate Faculty of Toxicology (TAMU) 

1990 - present: Professor; Intercollegiate Faculty of Food Science (TAMU) 

1990 - present: Professor; Veterinary Integrative Biosciences, College of Veterinary Medicine (TAMU) 

2001 - 2005: Chair, Intercollegiate Faculty of Toxicology (TAMU) 

2001 - 2006: Director, Center for Food Safety, Texas A&M University (TAMU) 

Honors and Research Awards 

TAMU Faculty Distinguished Achievement Award in Research, 2006 

Bush Award for Excellence in International Research (Bush Library, 2005) 

Sigma Xi Distinguished Scientist Award (TAMU, 2003) 

Co-Editor of Food Additives & Contaminants, Taylor & Francis Ltd., Oxforshire, U.K. 

Faculty Fellow distinction, Texas Agricultural Experiment Station, 2002 

BIFAD Chair’s Award for Scientific Excellence, Capitol Hill, Washington, D.C., 2002 

Pfizer Award for Excellence in Research, 1998 

SmithKline Beecham Award for Research, 1993 

Engelhard Chemical Corporation Achievement Award for Research, 1989 

TAMU Faculty Distinguished Achievement Award in Research, 1988 

Texas A&M University System Award in Research, 1986 

Faculty Achievement Award in Research (Texas Veterinary Medical Association), 1985 

Robert A. Welch Foundation Postdoctoral Fellowship, 1980 

National Defense and Education Act (NDEA) Predoctoral Fellowship, 1975 

Professional Interests 

Food Toxicology and Environmental Chemistry. The development and evaluation of chemical and biological 

methods to detect and detoxify hazardous chemicals and microbes. Molecular characterization of the 

mechanisms involved in the actions and interactions of food and environmental contaminants. 

Patents 

Phillips et al. 1992. Selective immobilization and detection of mycotoxins in solution: U.S. Patent No. 

5,178,832; TargetTM technology licensed by the Texas A&M System to: TerraTek Inc., Salt Lake City, UT and 

Vicam, Inc., Watertown, MA. 

Taylor et al. 1993. Method for inactivating mycotoxins present in animal feed: 1993 U.S. Patent No. 5,165,946. 

NovaSil TM technology licensed by the Texas A&M System to: Engelhard Chemicals, Cleveland, OH and DuCoa 

International, Highland, IL.

B. SELECTED PEER-REVIEWED PUBLICATIONS (From 159 journal articles): 

1. Bingham, A. K., Huebner, H. J., Phillips, T. D., and Bauer, J. E. 2004. Identification and reduction of urinary 

aflatoxin metabolites in dogs. Food and Chemical Toxicology, 42, 1851–1858. 

2. Huebner, H. J., Herrera, P. and Phillips, T. D., 2004. Clay-Based Interventions for the Control of Chemical 

and Microbial Hazards in Food and Water. In R. Beier, S. D. Pillai, and T. D. Phillips, eds., Pre-Harvest and 

Post-Harvest Food Safety: Contemporary Issues and Future Directions, IFT Press, Ames, IA, pp. 389-402. 

3. Wiles, M. C., Huebner, H. J., Afriyie-Gyawu, E., Taylor, R. J., Bratton, G. R. and Phillips, T. D., 2004. Toxicological 

evaluation and metal bioavailability in pregnant rats following exposure to clay minerals in the 

diet. Journal of Toxicology and Environmental Health, Part A 67(11), 863-874. 

4. Pimpukdee, K. Kubena, L. F., Bailey, C. A., Huebner, H. J., Afriyie-Gyawu, E. and Phillips, T. D., 2004. 

Afla-toxin-induced toxicity and depletion of hepatic vitamin A in young broiler chicks: Protection of chicks in 

the presence of low levels of NovaSil PLUS in the diet. Poultry Science 83(5), 737-744. 

5. Williams, J.H., Phillips, T.D., Jolly, P.E., Stiles, J.K., Jolly, C.M. and Aggarwal, D. 2004. Human 

aflatoxicosis in developing countries: A review of toxicology, exposure, potential health consequences and 

interventions. Am. J. Clin Nutr 80: 1106-22. 

6. Qin C, Morrow D, Stewart J, Spencer K, Porter W, Smith R 3rd, Phillips T, Abdelrahim M, Samudio I, Safe 

S. 2004. A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that 

inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes. Mol Cancer Ther. 

3 (3):247-60. 

7. Cizmas L, McDonald TJ, Phillips TD, Gillespie AM, Lingenfelter RA, Kubena LF, Phillips TD, Donnelly KC. 

2004. Toxicity characterization of complex mixtures using biological and chemical analysis in preparation 

for assessment of mixture similarity. Environ Sci Technol. 38(19):5127-33. 

8. Afriyie-Gyawu, E., Mayura, K., Wiles, M. C., Huebner, H. J., Julian, J., Fickey, C. and Phillips, T. D., 2005. 

Prevention of zearalenone-induced hyperestrogenism in prepubertal mice. J. Toxicol Environ. Hlth. Part A. 

68: 353-368. 

9. Afriyie-Gyawu, E., Mackie, J., Dash, B., Wiles, M., Taylor, J., Huebner, H., Tang, L., Guan, H., Wang, J.-S., 

and Phillips, T.D. 2005. Chronic toxicological evaluation of dietary NovaSil clay in Sprague-Dawley rats. 

Food Additives & Contaminants, 22(3): 259-269. 

10. Wang, J.-S., Luo, H., Billam, M., Wang, Z., Guan, H., Tang, L., Goldston, T., Afriyie-Gyawu, E., Lovett, C., 

Griswold, J., Brattin, B., Taylor, R.J., Huebner, H.J. and Phillips, T.D., 2005. Short-term safety evaluation of 

processed calcium montmorillonite clay (NS) in humans. Fd. Additives & Contam., 22(3): 270-279. 

11. Wiles, M. C., Ake, C. L., Donnelly, K. C., McDonald, T. J., Huebner, H. J., Burghardt, R. C., and Phillips, T. 

D., 2005. Matrix-immobilized organoclay for the removal of toxic contaminants from groundwater. 

Chemosphere, 59(10):1455-64. 

12. Ottinger, S., Barhoumi, R., McKenzie, K.S., McDonald, T., Burghardt, R. and Phillips, T.D. 2005. FIA/MS 

analysis of temporally ozonated benzo[a]pyrene and pyrene and their reaction products: Inhibition of gap 

junction mediated intercellular communication. Chemosphere, 60(8):1025-1033. 

13. Jiang, Y., Jolly, P., Elllis, W., Wang, J.-S., Phillips, T., and Williams, J. 2005. Aflatoxin B1 albumin adduct 

14. levels and cellular immume status in Ghanaians. International Immunology, 17(6): 807-814. 

15. Dash, B., Afriyie-Gyawu, E., Huebner, H.J., Porter, W., Wang, J.S., Jolly, P.E., and Phillips, T.D. 2006. 

Noninvasive identification of inter-individual variation in xenobiotic metabolizing enzymes: Implications for 

cancer epidemiology and biomarker studies. J. Toxicol. Environ. Health A, 69(13): 1203-16. 

16. Jolly, P., Jiang, Y., Ellis, W., Awuah, R., Nnedu, O., Phillips, T., Wang, J.-S., Afriyie-Gyawu, E., Tang, L., 

Person, S., Williams, J. and Jolly, C. 2006. Determinants of aflatoxin levels in Ghanaians: 

Sociodemographic factors, knowledge of aflatoxin and food handling and consumption practices, Int. J. 

Hyg. Environ.-Health 209: 345–358. 

17. Dash, B., Metz, R., Huebner, H.J., Porter, W. and Phillips, T.D. 2006. Molecular characterization of 

phospholipid hydroperoxide glutathione peroxidases from Hydra vulgaris. Gene 381:1-12. 

18. Dash, B., Metz, R., Huebner, H.J., Porter, W. and Phillips, T.D. 2007. Molecular characterization of two 

superoxide dismutases from Hydra vulgaris. Gene 387:93-108. 

19. Dash, B., Afriyie-Gyawu, E., Huebner, H.J., Porter, W., Wang, J.S., Jolly, P.E., and Phillips, T.D. 2007. 

Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians. J. Toxicol. Environ. Health 

A, Jan, 70(1): 58-66.




NAME 

Mirkes, Philip E. 



Professor; 

Director, Center for Environmental and Rural Health 



DEGREE 


YEAR(s) 

St. Norbert College, DePere, WI BS 1965 Biology 

University of Michigan, Ann Arbor, MI MS 1967 Zoology 

University of Michigan, Ann Arbor, MI PhD 1970 Zoology 



Positions and Employment 

1970-1971 NIH Postdoctoral Trainee, Department of Zoology, University of Washington 

1971-1973 NIH Postdoctoral Fellow, Department of Genetics, University of Washington 

1973-1979 Assistant Professor, Department of Biology, University of South Carolina 

1979-1982 Research Assistant Professor, Department of Pediatrics, University of Washington, Seattle 

1983-1991 Research Associate Professor, Department of Pediatrics, University of Washington, Seattle 

1992-2004 Research Professor, Department of Pediatrics, University of Washington, Seattle 

2004-Present Professor, Department of Veterinary Physiology and Pharmacology, Texas A&M University 

2004-Present Director, Center for Environmental and Rural Health, Texas A&M University 

Other Experience and Professional Memberships 

1985-1992 Member, March of Dimes Reproductive Hazards in the Workplace Research Advisory 

Committee 

1988-1989 Fogarty Senior International Fellow, Experimental Embryology and Teratology Unit, Medical 

Research Council, London, England; Host Dr. Nigel Brown 

1992-1996 Member, NIH HED-2 Study Section 

1997-2000 Member, National Academy of Sciences/National Research Council Committee on 

Developmental Toxicology 

1998-1999 President, Teratology Society 

2003-Present Editor-in-Chief, Birth Defects Research: Clinical and Molecular Teratology 

Honors 

1988-1989 Fogarty Senior International Fellowship Award 

1979-1982 NIEHS Mid-career Development Award, Toxicology 

B. Selected peer-reviewed publications (in chronological order). 

1. Mirkes PE, Doggett B, Cornel L (1994) Induction of a heat shock response (HSP 72) in rat embryos 

exposed to selected chemical teratogens. Teratology 49:135-142. 

2. Cunningham ML, MacAuley A, Mirkes PE (1994) From gastrulation to neurulation: transition in retinoic acid 

sensitivity identifies distinct stages of neural patterning in the rat. Dev. Dynamics 200:227-241. 

3. Fuginaga M, Park HW, Shepard TH, Mirkes PE, Baden, JM (1994) Staurosporine does not prevent 

adrenergic-induced situs inversus, but causes a unique syndrome of defects in rat embryos grown in 

culture. Teratology 50:261-274. 

4. Thayer JM, Giachelli CM, Mirkes PE, Schwartz SM (1995) Expression of osteopontin in the head process 

late in gastrulation in the rat. J. Exptl. Zool. 272:240-244. 

5. Little SA, Mirkes PE (1995) Clustering expression during programmed and teratogen-induced cell death in 

the postimplantation rat embryo. Teratology 52:41-54.

6. Thayer JM, Mirkes PE (1995) Programmed cell death and N-Acetoxy-2-Acetylaminofluorene-induced 

apoptosis in the rat embryo. Teratology 51:418-429. 

7. Lee QP, Park HW, Thayer J, Mirkes PE, Juchau MR (1996) Apoptosis induced in cultured rat embryos by 

intra-amniotically microinjected sodium nitroprusside. Teratology 53:21-30. 

8. Mirkes PE (1996) Prospect for the development of validated screening tests that measure developmental 

toxicity potential: view of one skeptic. Teratology 53:334-338. 

9. Qwihee P Lee, Park HW, Thayer J, Mirkes PE, Juchau MR (1996) Apoptosis induced in cultured rat 

embryos by intra-amniotically microinjected sodium nitroprusside. Teratology 53:21-30. 

10. Mirkes PE, Little SA, Cornel L, Welsh MJ, Laney T-NN, Wright FH (1996) Induction of Heat Shock Protein 

27 (Hsp 27) in rat embryos exposed to hyperthermia. Mol. Reprod. Develop. 45:276-284. 

11. Thayer JM, Mirkes PE (1997) Induction of Hsp72 and Transient nuclear localization of Hsc73 and Hsp72 

correlate with the acquisition and loss of thermotolerance in postimplantation rat embryos. Dev. 

12. Dev. Dynamics, 208:227-243. 

13. Mirkes PE (1997) Molecular/cellular biology of the heat stress response and its role in agent-induced 

teratogenesis. Mutation Res. 396:163-173. 

14. Bratton SL Jardine DS, Mirkes PE (1997) Constitutive synthesis of heat shock protein (72kD) in human 

peripheral blood mononuclear cells: Implications for use as a clinical test of recent thermal stress. Int. J. 

Hyperthermia 13:157-168. 

15. Mirkes PE, Cornel LM, Park HW, Cunningham ML (1997) Induction of thermotolerance in early 

postimplantation rat embryos is associated with increased resistance to hyperthermia-induced apoptosis. 

Teratology 56:210-219. 

16. Mirkes PE, Little SA (1998) Teratogen-induced cell death in postimplantation mouse embryos: 

differential tissue sensitivity and hallmarks of apoptosis. Cell Death & Differen. 5:592,600. 

17. Mirkes PE, LM Cornel, KL Wilson, WH Dilmann (1999) Heat shock protein 70 (HSP 70) protects 

postimplantation murine embryos from the embryolethal effects of hyperthermia. Dev. Dynamics 

214:159-170. 

18. Mirkes PE, Little SA (2000) Cytochorome c release from mitochondria of early postimplantation 

murine embryos exposed to cyclophosphamide, heat shock and staurosporine. Toxicol. Appl. 

Pharmacol. 162:197-206. Received the Best Paper Award from the Reproductive and 

Developmental Toxicology Specialty Section of the Society of Toxicology. 

19. Mirkes PE, Wilson KL, Cornel LM (2000) Teratogen-induced activation of ERK-JNK, and p38 MAP 

kinases in early postimplantation murine embryos. Teratology 62:14-25. 

20. Umpierre CC, Little SA, Mirkes PE (2001) Co-localization of active caspase-3 and DNA fragmentation 

(TUNEL) in normal and hyperthermia-induced abnormal mouse development. Teratology 63:134-143. 

Nominated for James G. Wilson Publication Award-best paper published in Teratology in 2000-2001. 

21. Mirkes PE (2002) 2001 Warkany Lecture: To die or Not to Die, the Role of Apoptosis in Normal and 

Abnormal Mammalian Development. Teratology 65:228-239. 

22. Little SA, Mirkes PE (2002) Teratogen-induced activation of caspase-9 and the mitochondrial apoptotic 

pathway in early postimplantation mouse embryos. Toxicol. Appl. Pharmacol. 181:142-151. 

23. Soleman D, Cornel L, Little SA, Mirkes PE (2003) Teratogen-induced activation of the mitochondrial 

apoptotic pathway in the yolk sac of day 9 mouse embryos. Birth Defects Research (Part A) 67:98-107. 

24. Won-Kyu K, Mirkes PE (2003) Alterations in mitochondrial morphology are associated with hyperthermiainduced 

apoptosis in early postimplantation mouse embryos. Birth Defects Res. (Part A) (in press). 

25. Little SA, Mirkes PE (2003) Teratogen-induced activation of caspase-6 and caspase-7 in early 

postimplantation mouse embryos. Cell Biol. Toxicol. 19:215-226. 

26. Mikheeva S, Barrier M, Little SA, Beyer R, Mikheev AM, Kerr MK, Mirkes PE (2004) Alterations in gene 

expression induced in day 9 mouse embryos exposed to hyperthermia or 4-hydroperoxycyclophosphamide 

(4CP): Analysis using cDNA microarrays. Tox. Sci. 79:345-359. 

27. Barrier M, Mirkes PE (2005) Proteomics in Developmental Toxicology. Repro. Toxicol.19:291-304. 

28. Hosako H., Little SA, Barrier M, and Mirkes PE (2006) Teratogen-induced activation of o53 in early 

postimplantation mouse embryos. Toxicol. Sci. 95:257-269.




NAME 

Porter, Weston 



Assistant Professor 



DEGREE 


YEAR(s) 


Texas A&M University, College Station, TX B.S. 1991 Genetics 

Texas A&M University, College Station, TX Ph.D. 1997 Toxicology 

HHMI-UT Southwestern Medical Institute, Dallas, Postdoc. 1997-1998 Molecular Endocrinology 

Baylor College of Medicine, Houston, TX Postdoc. 1998-2001 Cell Biology 



2001-present Assistant Professor, Department of Veterinary Anatomy and Public Health, Texas A&M 



American Association for Cancer Research (AACR) 

Society of Toxicology (SOT) 

Honors 

Susan G. Komen Breast Cancer Foundation Postdoctoral Fellowship (1999-2001) 

Texas A&M Association of Former Students - Distinguished Graduate Student Award-(1997-1998) 

Society of Toxicology Student Fellowship-Procter and Gamble Award (1996) 

Gulf Coast Society of Toxicology-First Place Poster Competition (1996) 

George T. Edds Toxicology Outstanding Graduate Student Award (1995) 

National Institutes of Environmental Health Training Grant Fellowship (1992-1996) 

B. Selected peer-reviewed publications (in chronological order). Total of 29. 

1. Porter, W., Duan, R. and Safe, S. Inhibition of estrogen-induced heast shock protein 27 (HSP27) gene 

expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 human breast cancer cells. 

Organohalogen Compounds 21:319-321, 1994. 

2. Wang, W., Thomsen, J.S., Porter, W., Moore, M. and Safe, S. A novel mechanism for restoring aryl 

hydrocarbon (Ah)-responsiveness in Hs578T human breast cancer cells. Organhalogen Compounds 

25:395-3987, 1995. 

3. Krishnan, V., Porter, W., Santostefano, M., Wang, X. and Safe, S. Inhibition of estrogen-induced 

cathepsin-D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells: molecular 

mechanism. Mol. Cell Biol. 15:6710-6719, 1995. 

4. Wang, W., Thomsen, J., Porter, W., Moore, M. and Safe, S. Effects of transient expression of the 

estrogen receptor on constitutive and inducible CYP1A1 in Hs578T human breast cancer cells. Br. J. 

Cancer 73: 316-322, 1996. 

5. Porter, W., Wang, F., Wang, W. , Duan, R. and Safe, S. Mechanism of estrogen-induced Hsp27 gene 

expression. Mol. Endocrinol. 10:1371-1378, 1996. 

6. Safe, S, Chen, I., Porter, W. (1996) Dietary indoles with antiestrogenic activity in common vegetables and 

their implications. In Estrogens, Progestins and Their Antagonsists (Pavlik E.J., Ed.). Birkhauser, Boston. 

7. Gillesby, B.E., Stanostefano, M., Porter, W., Safe, S., Wu, Z.H. and Zacharewski, T.R. Identification of a 

motif within the 5’ regulatory region of pS2 which is responsible for AP-1 binding and TCDD-mediated 

suppression. Biochemistry 36:6080-6089, 1997.

8. Wang, W., Porter, W., Burghardt, R. and Safe, S. Mechanism of inhibition of MDA-468 breast cancer cell 

growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Carcinogenesis 19:925-933, 1997. 

9. Porter, W., Saville, B., Hoivik, D. and Safe, S. Functional synergy between the transcription factor Sp1 

and the estrogen receptor. Mol. Endocrinol. 11:1569-1580, 1997. 

10. Wang, F., Porter, W. and Safe, S. Identification of a functional imperfect estrogen-responsive element in 

the 5’-promoter region of the human cathepsin D gene. Biochemistry 36:7793-7801, 1997. 

11. Duan, R., Porter, W. and Safe, S. Estrogen-induced c-fos protooncogene expression in MCF-7 human 

breast cancer cells: role of estrogen receptor Sp1 complex formation. Endocrinology139:1981-1990, 1998. 

12. Sun, G., Porter, W. and Safe, S. Estrogen-induced retinoic acid receptor α1 gene expression: role of 

estrogen receptor-Sp1 complex. Mol. Endocrinol. 12:882-890, 1998. 

13. Safe, S., Wang, F., Porter, W., Duan, R. and McDougal, A. Ah-receptor agonists as endocrine disruptors: 

antiestrogenic activity and mechanisms. Toxicol. Lett. 102-103:343-347, 1998. 

14. Safe, S and Porter, W. (1999) Estrogenic and antiestrogenic compounds. In Molecular Biology of the 

Toxic Response (Puga, A. and Wallace, K., Eds.). Taylor and Francis, Washington. 

15. Suh, N, Wang, Y, Hondo, T, Gribble, GW, Dmitrovsky, E, Hickey, WF, Maue, RA, Place, AE, Porter, DM, 

Spinella, MJ, Williams, CR, Wu, G, Dannenberg, AJ, Flanders, KC, Letterio, JJ, Mangelsdorf, DJ, Nathan, 

CF, Nguyen, L., Porter WW, Ren, RF, Roberts, AB, Roche, NS, Subbaramaiah, K. and Sporn, M.B. A 

novel synthetic riterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, 

antiproliferative and anti-inflammatory activity. Cancer Res. 59:336-341, 1999. 

16. Duan, R., Porter, W., Samudio, I., Vyhlidal, C., Kladde, M. and Safe, S. Transcriptional activation of c-fos 

protooncogene by 17β-estradiol: mechanism of aryl hydrocarbon receptor-mediated inhibition. Mol. 

Endocrinol. 13:1511-1521, 1999. 

17. Porter, WW, Wang, Y., Suh, N., Honda, T, Gribble, G.W., Leesnitzer, L.M., Plunket, K.D., Mangelsdorf, 

D.J., Blanchard, S.G., Willson, T.M. and Sporn, M.B. A synthetic triterpenoid, 2-cyano-3,12-dioxooleana- 

1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator activated receptor γ. Mol. 

Endocrinol. 14:1550-1556, 2000. 

18. Porter, W.W., Fang, F., Duan, R., Qin, C., Castro-Rivera, E., Kim, K. and Safe, S. Transcriptional 

Regulation of the heat shock protein 27 gene expression by 17β-estradiol and modulation by antiestrogen 

and aryl hydrocarbon receptor agonists. J. Mol. Endocrinol. 26:31-42, 2001. 

19. Qin, C, Morrow, D., Stewart, J., Spencer, IK., Porter, W., Smith III, R., Phillips,T., Abdelrahim, m., 

Samudio, I. And Safe, S. A new class of peroxisome proliferator-activated receptor γ (PPARγ) agonists 

that inhibit growth of breast cancer cells. Mol Cancer Therap. 3:247-259, 2004. 

20. Metz, RP, Qu, X, Laffin, B, Earnest, D, Porter, W Circadian clock and cell cycle gene expression in mouse 

mammary epithelial cells and in developing mouse mammary gland. Dev Dynamics 235:263-271, 2006. 

21. Metz, R.P., Kwak, H., Gustafson, T., and Porter, W. Differential transcriptional regulation by mouse 

Singleminded2s. J Biol Chem 281:10839-48, 2006. 

22. McDaniel SM, Rumer KK, Biroc, SL, Metz, RP, Singh, M. Porter, W and Schedin, P Remodeling of the 

mammary microenvironment after lacation promotes breast tumor cell metastasis. Am J Pathol 168:608- 

20, 2006. 

23. Higgins KJ, Liu S, Abdelrahim M, Yoon K, Vanderlaag K, Porter W, Metz RP, Safe S. Vascular Endothelial 

Growth Factor Receptor-2 Expression Is Induced By 17b-Estradiol In ZR-75 Breast Cancer Cells By 

Estrogen Receptor a/Sp Proteins. Endocrinology 147:3285-3295, 2006. 

24. Dash B, E Afriyie-Gyawu, HJ Huebner, W Porter, JS Wang, PE Jolly, TD Phillips. Noninvasive 

Identification of Inter-individual Variation in Xenobiotic Metabolizing Enzymes: Implications for Cancer 

Epidemiology and Biomarker Studies. J Toxicol Environ Health A 69:1203-1216, 2006. 

25. Dash, E. Afriyie-Gyawu, H. J. Huebner, W. Porter, 1J. S. Wang, 2P. E. Jolly, T. D. Phillips. Host 

factors in the variability of aflatoxin-albumin adduct levels: Microsomal epoxide hydrolase genotype 

may be associated with the variability of aflatoxin-albumin adduct levels in Ghanaians (Accepted). 

26. Hyeong-Il Kwak, Richard P. Metz, Kristin Kucera, Abby Williams, Pepper Schedin and Weston W. 

Porter. The Down Syndrome Gene Singleminded-2s is a Putative Breast Tumor Suppressor Gene (In 

Press, Carcinogenesis). 

27. B Laffin, H-I Kwak, R Metz, P Schedin and WW Porter. Single-minded 2 is a Master Regulator of 

Morphogenesis (submitted).




NAME 

Ramaiah, Shashi K. 


RamaiahS 





DEGREE 




1994-1995 Research Worker, Indian Institute of Science, Bangalore, India 

1993-1994 Project Assistant, Indian Institute of Science, Bangalore, India 

1993-1995 Graduate Assistant, Department of Pharmacology, Veterinary College, India 

1996-1999 Graduate Assistant, Division of Toxicology, University of Louisiana at Monroe, LA 

1997-1999 Special Research Employee, FDA, National Center for Toxicological Research, AR 

1999-2002 Clinical Pathology Resident, College of Veterinary Medicine, Univ. of Florida, Gainesville, FL 

2002-Present Assistant Professor, Department of Pathobiology, College of Veterinary Medicine, Texas 

Veterinary Medical Center, Texas A&M University, College Station, TX 

2003-Present Interdisciplinary Faculty of Toxicology, College of Veterinary Medicine, Texas A&M 



International Journal of Toxicology, 2002-to date; Veterinary Clinical Pathology, 2004-date 

Board Certification 

Diplomate American College of Veterinary Pathology (DACVP), 2002 

Diplomate American Board of Toxicology (DABT), 2006 

YEAR(s) 

Professional Societies 

American Veterinary Medical Association; American College of Veterinary Pathology 

American Society for Veterinary Clinical Pathology; Society of Toxicology 

American College of Toxicology, Society of Toxicologic Pathology 


University of Agricultural Sciences, Bangalore, DVM 1992 Veterinary Medicine 

University of Agricultural Sciences, Bangalore, M.V.Sc. 1995 Pharmacology 

University of Louisiana at Monroe, LA Ph.D. 1999 Pharmacology/Toxicolog 

University of Florida, Gainesville, FL Residency 2002 Clinical Pathology 

University of Florida, Gainesville, FL Diplomate 2002 Clinical Pathology 

Honors and Awards 

2006, Chair, Continuing Education Committee, Society of Toxicologic Pathology 

2006, Elected Secretary of the Gulf Coast Chapter of the Society of Toxicology (GCSOT) 

2005, Co-Chair, Continuing Education Committee, Society of Toxicologic Pathology 

2002 C. L. Davis Award (University of Florida), ACVP Annual Meeting, New Orleans. 

2001 Young Investigator Award Poster Competition, ACVP Annual Meeting, Salt Lake City. 

2000 First Place in the Young Investigator Award Poster (Experimental Disease), ACVP Annual Meeting 

2000 Phi Zeta Best Paper Award by a Veterinarian, College of Veterinary Medicine, Univ. Florida 

1999 Resident Research grant, College of Veterinary Medicine 

1999 School of Pharmacy Award for Excellence in Research, University of Louisiana at Monroe 

1999 Best Research Award, Division of Toxicology, University of Louisiana at Monroe 

1999 Best Paper published in Toxicology and Applied Pharmacology, Board of Publication (SOT)

1999 Taylor and Francis, Best Paper Award in Food Safety Specialty Section, SOT 

1998 Academy of Toxicological Sciences Award for Best Paper, American College of Toxicology 

1998 Best Paper at the Risk Assessment Specialty Section, SOT 

1998 Carl Smith Mechanisms Specialty Section Honorable Mention for Best Paper, SOT 

1998 Travel Fellowship from Society of Toxicology 

1998 Grants-in-Aid Research Award from Sigma Xi, the Scientific Research Society 

1997 Young Investigator Award from the SCC-Society of Toxicology 

1997 George Bacon Scholarship from the Louisiana Cancer Registry 

1997 Academy of Toxicological Sciences Fellowship for Best Paper from the American College of Toxicology 

B. Selected peer-reviewed publications (in chronological order) 

1. Ramaiah, S.K., Bucci, T. J., Soni, M. G., Warbritton, A., and Mehendale, H. M. 1998. Temporal changes in 

tissue repair permit survival of diet restricted rats from an acute lethal dose of thioacetamide: Mechanism 

for survival. Tox. Sci. 45: 233-241. 

2. Ramaiah, S. K., Soni, M. G., Bucci, T. J., and Mehendale, H. M. 1998. Diet restriction enhances 

compensatory liver tissue repair and survival following administration of lethal dose of thioacetamide. 

Toxicol. Appl. Pharmacol. 150: 12-21 (Best Paper Award, 1999). 

3. Soni, M.G., Ramaiah, S.K., Mumtaz, M., Clewell, H., and Mehendale, H.M. 1999. Toxicant-inflicted injury 

and stimulated tissue repair are opposing toxicodynamic forces in predictive toxicology. Reg. Pharmacol 

and Toxicol. 29: 165-174. 

4. Ramaiah, S. K., Udayan Apte and Mehendale, H. M. 2000. Diet restriction and non-cancer end-points of 

toxicity: A review. Internat. J. Toxicol. 19: 413-424. 

5. Ramaiah, S. K., Apte, U., and Mehendale, H. M. 2001. Cytochrome P4502E1 increases thioacetamide 

liver injury in diet restricted rats. Drug Metab. Disp. 29: 1088-95. 

6. Ramaiah, S. K, and Alleman AR. 2002. Liver cytology: Aspirations and limitations. Compendium, 24, 798- 

810. 

7. Apte, U. M., Limaye, P., Ramaiah, S. K., Vaidya SV., Bucci, TJ., Warbritton, A and Mehendale HM. 2002. 

Upregulated signaling via cytokines and growth factors is the mechanism of robust liver tissue repair in 

thioacetamide-induced hepatotoxicity in caloric restricted rats. Tox. Sci. 69: 448-459. 

8. Ramaiah, S. K., Alleman R., Hanel, R., and Uhl, E. 2002. A mass in the ventral neck of a hypercalcemic 

dog. Vet. Clin. Path. 30: 177-179. 

9. Ramaiah, S. K., Seguin, A., Carwile, H., and Raskin, R. 2002. Biclonal gammopathy associated with 

immunoglobulin A in a dog with multiple myeloma. Vet. Clin. Path. 31: 83-89. 

10. Ramaiah, S. K., Harvey, J., Gigure, S., and Franklin, R. 2003. Intravascular hemolysis associated with 

liver failure concurrent to neutrophil hypersegmentation in the horse. J. Vet. Int. Med. 17: 360-363. 

11. Ramaiah, S. K., Rivera, C., and Arteel, G. 2004. Early phase alcoholic liver disease: Pathology, 

pathogenesis and animal models. Internat. J. Toxicol. 23: 1-15. 

12. Apte, U. M., McRee, R., and Ramaiah, SK. 2004. Increased Hepatocyte Division Leads To Transient 

Decrease In Liver Injury During Initial Period of Chronic Ethanol consumption. Tox. Path. 32: 1-10. 

13. Apte, U.M., Banerjee, A., McRee, R., Wellberg, E., and Ramaiah, S.K., Role of osteopontin in Hepatic 

Neutrophil Infiltration during Alcoholic Steatohepatitis, Toxicol. Appl. Pharmacol. 207: 25-38, 2005. 

14. Chintharlapalli, S. Burghardt,, R., Papineni, S., Ramaiah, S., Yoon, K. and Safe, S. Activation of Nur77 

by selected 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl) methanes induces apoptosis through nuclear 

pathways. Journal of Biol. Chem. 280: 24903-14, 2005. 

15. Banerjee, A., Apte, UM, Smith III, R., and Ramaiah, S. K. Higher neutrophil infiltration mediated by 

osteopontin is the likely contributing factor for increased susceptibility of females to Alcoholic Liver 

Disease. J. Pathology. 208: 473-85, 2006 

16. Banerjee, A., Burghardt, R., Johnson, G., White, F., and Ramaiah, S. K. Potential role of osteopontin as a 

predictive biomarker in a rat model of alcoholic steatohepatitis. Toxicologic Pathology 34: 373-384, 2006 

17. Rose, R., Banerjee, A., and Ramaiah, S. K. Calpain inhibition attenuates iNOS production and 

midzonal hepatic necrosis in a repeat dose model of endotoxemia in rats. Toxicologic Pathology. 

34:785-794, 2006.

NAME 




SAFE, Stephen H. 


ssafe1 


Distinguished Professor 

EDUCATION (Begin with baccalareate or other initial professional education, such as nursing, and include postdoctoral training.) 

INSTITUTION AND LOCATION DEGREE YEAR(s) FIELD OF STUDY 

Queen's University - Canada B.S. 1962 Chemistry 

Queen's University - Canada M.S. 1963 Chemistry 

Oxford University - Great Britain D.Phil. 1965 Bioorganic Chemistry 

Oxford University - Great Britain Res. Asst. 1966 Bioorganic Chemistry 

Harvard University - USA Res. Assoc. 1967 Biochemistry 

A. POSITIONS AND HONORS 


1968-1973 Research Officer, National Research Council of Canada 

1973-1977 Associate Professor, Department of Chemistry, University of Guelph 

1977-1981 Professor, Department of Chemistry, University of Guelph 

1984- Distinguished Prof., Dept. of Veterinary Physiology & Pharmacology, Texas A&M University 


1976 Sigma Xi Award for Excellence in Research, University of Guelph 

1978 Queen's Silver Jubilee Medal 

1984 Royal Society of Chemistry Award for Safety, Health or Environmental Chemistry 

1989-1994 Burroughs Wellcome Toxicology Scholar Award 

1991-1992 University Lecturer, Texas A&M University 

1991 Sid Kyle Chair in Toxicology, Texas A&M University 

1988 Distinguished Achievement Award in Research, Texas A&M University 

1995 Distinguished Achievement Award in Research, Sigma XI 

1995 Eli Lilly Science and Society Lecturer, Indiana State University 

1996 Samuel Kuna Distinguished Lecturer, Rutgers University - UMDNJ 

1996 Honorary Doctorate in Science, University of Guelph 

1998 McEwen Lecturer, Queen’s University 

2002 ISI, Most Highly Cited Research in Pharmacology and in Ecology/Environment 

2003 Spirit of Innovation Award, Technology Licensing Office, Texas A&M University 

2004 Jo Ann Treat Award for Excellence in Research, Texas A&M Research Foundation 

2005 Texas A&M Univ. Former Students Association Distinguished Achievement Award for Research 

B. SELECTED REPRESENTATIVE PUBLICATIONS (Refereed - >570; Books - 5) 

Samudio I, Konopleva M, Hail, Jr. N., Shi Y-X, McQueen T, Hsu T, Evans R, Honda T, Gribble GW, Sporn M, 

Gilbert HF, Safe S and Andreeff M. 2-Cyano-3,12-dioxooleana-1,9-diene-28-imidazolide (CDDO-Im) 

directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer. J Biol Chem 280:36273- 

36282, 2005. 

Mitchell DC, Abdelrahim M, Weng J, Stafford LJ, Safe S, Bar-Eli M and Liu M. Regulation of KiSS-1 metastasis 

suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator 

protein-2α and specificity protein-1. J Biol Chem 281:51-58, 2005. 

Zhang S, Li X, Burghardt R, Smith III R and Safe S. Role of estrogen receptor α (ERα) in insulin-like growth 

factor-1 (IGF-1)-induced responses in MCF-7 breast cancer cells. J. Mol. Endocrinol. 35:433-447, 2005. 

Lee SH, Yamaguchi K, Kim JS, Eling TE, Safe S, Park Y and Baek SJ. Conjugated linoleic acid stimulates antitumorigenic 

protein NAG-1 in an isomer specific manner. Carcinogenesis 27:972-981, 2006. 

Vanderlaag K, Samudio I, Burghardt R, Barhoumi R and Safe S. Inhibition of breast cancer cell growth and

induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM. Cancer Lett. 236:198-212, 

2006. 

Abdelrahim M, Newman K, Vanderlaag K, Samudio I and Safe S. 3,3'-Diindolylmethane (DIM) and derivatives 

induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation 

of DR5. Carcinogenesis 27:717-728, 2006. 

Fleming JG, Spencer TE, Safe SH and Bazer FW. Estrogen regulates transcription of the ovine oxytocin 

receptor gene through GC-rich Sp1 promoter elements. Endocrinology 147:899-911, 2006. 

Mitchell DC, Abdelrahim M, Weng J, Stafford LJ, Safe S, Bar-Eli M and Liu M. Regulation of KiSS-1 metastasis 

suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator 

protein-2α and specificity protein-1. J. Biol. Chem. 281:51-58, 2006. 

Kassouf W, Chintharlapalli S, Abdelrahim M, Nelkin G, Safe S and Kamat AM. Inhibition of bladder tumor 

growth by 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes: a new class of peroxisome proliferatoractivated 

receptor γ agonists. Cancer Res. 66:412-418, 2006. 

Li X, Zhang S and Safe S. Activation of kinase pathways in MCF-7 cells by 17β-estradiol and structurallydiverse 

estrogenic compounds. J Ster Biochem Mol Biol 98:122-132, 2006. 

Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt R, Liu S, Hill D, Finnell R, Wlodarczyk B, 

Jordan VC and Safe S. 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly 

activate estrogen receptor α. Cancer Res. 66:2459-2467, 2006. 

Konopleva M, Zhang W, Shi YX, McQueen T, Tsao T, Abdelrahim M, Munsell MF, Johansen M, Yu D, Madden 

T, Safe SH, Hung MC and Andreeff M. Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic 

acid induces growth arrest in HER2-overexpressing breast cancer cells. Mol Cancer Ther 2:317-328, 2006. 

Higgins KJ, Abdelrahim M, Liu S, Yoon K and Safe S. Regulation of vascular endothelial growth factor 

receptor-2 expression in pancreatic cancer cells by Sp proteins. Biochem Biophys Res Commun. 345:292- 

301, 2006. 

Chintharlapalli C, Papineni S and Safe S. 1-1-Bis(3'-indolyl)-1-(p-substituted phenyl) methanes inhibit colon 

cancer cell and tumor growth through PPARγ-dependent and PPARγ-independent pathways. Mol. Cancer 

Ther. 5:1362-1370, 2006. 

Lee W-R, Chen C-C, Liu S and Safe S. 17β-Estradiol (E2) induces Cdc25A gene expression in breast cancer 

cells by genomic and non-genomic pathways. J Cel. Biochem 99:209-220, 2006. 

Higgins KJ, Liu S, Abdelrahim M, Yoon K, Vanderlaag K, Porter W, Metz RP and Safe S. Vascular endothelial 

growth factor receptor-2 expression is induced by 17α-estradiol in ZR-75 breast cancer cells by estrogen 

receptor α/Sp proteins. Endocrinology 147:3285-3295, 2006. 

Khan S, Barhoumi R, Burghardt R, Liu S, Kim K and Safe S. Molecular mechanism of inhibitory aryl 

hydrocarbon receptor-estrogen receptor/Sp1 crosstalk in breast cancer cells. Mol. Endocrinol. 20:1234- 

1237, 2006. 

Abdelrahim M, Baker CH, Abbruzzese JL and Safe S. Tolfenamic acid and pancreatic cancer growth, 

angiogenesis, and Sp protein degradation. J Natl Cancer Inst 98:855-868, 2006. 

Liu S, Abdelrahim M, Khan S, Ariazi E, Jordan VC and Safe S. Aryl hydrocarbon receptor agonists directly 

activate estrogen receptor α in MCF-7 breast cancer cells. Biol. Chem. 387:1209-1213, 2006. 

Lei P, Abdelrahim M and Safe S. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit ovarian cancer 

cell growth through peroxisome proliferator-activated receptor-dependent and independent pathways. Mol. 

Cancer Ther. 5:2324-2336, 2006. 

Chintharlapalli S, Papineni S, Safe S. 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce 

apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through PPAR-γindependent 

pathways. Mol Pharmacol.;71:558-69. Epub 2006 Nov 8, 2007. 

Wu F, Safe S. Differential activation of wild-type estrogen receptor α and C-terminal deletion mutants by 

estrogens, antiestrogens and xenoestrogens in breast cancer cells. J Steroid Biochem Mol Biol. 103:1-9, 

2007. 

Cho SD, Yoon K, Chintharlapalli S, Abdelrahim M, Lei P, Hamilton S, Khan S, Ramaiah SK, Safe S. Nur77 

agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptordependent 

and nuclear receptor-independent pathways. Cancer Res. 67:674-83, 2007. 

Lee J, Safe S. Coactivation of estrogen receptor alpha (ERα)/Sp1 by vitamin D receptor interacting protein 150 

(DRIP150). Arch Biochem Biophys. Epub 2007 Jan 23; 2007.




NAME 

Tian, Yanan 






DEGREE 


YEAR(s) 


South China Agriculture College B. S. 1982 Plant Sciences 

South China Agriculture University M. S. 1985 Plant Virology 

Rutgers University Ph.D. 1993 Molecular Genetics 



1986-1988 Research Assistant, Oregon Station University 

1988-1992 Research Assistant and Ph.D. student, Rutgers University 

1992-1993 Postdoctoral Fellow, University of Toronto 

1993-1999 Postdoctoral Fellow, UMDNJ-Robert Wood Johnson Medical School 

1999-2001 Assistant Professor, Environmental and Community Medicine, UMDNJ-Robert Wood Johnson 

Medical School 

2001-present Assistant Professor, College of Veterinary Medicine, Texas A&M University 


2001- Member, Interdisciplinary Faculty of Toxicology 

2002- Charter Fellow of the Michael E. DeBakey Institute for Comparative Cardiovascular Science 

and Biomedical Devices 

2002- Member, Executive Committee, Interdisciplinary Faculty of Toxicology 

2002- Member, Center for Environmental and Rural Health (CERH) 

Society of Toxicology (Full Membership) 

Gulf Coast Chapter, Society of Toxicology –Secretary (2005), Vice President (2006), 

President (2007) 

Honors 

1987 Merck Pre-doctoral Fellowship 

1997 The New Jersey Cancer Research Award for Scientific Excellence 


1. Hillman, B. I., Y. Tian, P. J. Bedker, and M. P. Brown. 1992. A North American hypovirulent isolate of 

the chestnut blight fungus with European isolate-related dsRNA. J Gen Virol 73:681-686. 

2. Jin, Y., D. E. Heck, G. DeGeorge, Y. Tian, and J. D. Laskin. 1996. 5-Fluorouracil suppresses nitric oxide 

biosynthesis in colon carcinoma cells. Cancer Res 56:1978-82. 

3. Tian, Y., S. Ke, T. Thomas, R. J. Meeker, and M. A. Gallo. 1998. Regulation of estrogen receptor mRNA 

by 2,3,7,8-tetrachlorodibenzo-p- dioxin as measured by competitive RT-PCR. J Biochem Mol Toxicol 

12:71-7. 

4. Tian, Y., S. Ke, T. Thomas, R. J. Meeker, and M. A. Gallo. 1998. Transcriptional suppression of 

estrogen receptor gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). J Steroid Biochem 

Mol Biol 67:17-24. 

5. Tian, Y., S. Ke, M. S. Denison, A. B. Rabson, and M. A. Gallo. 1999. Ah receptor and NF-kappaB 

interactions, a potential mechanism for dioxin toxicity. J Biol Chem 274:510-5. 

6. Ke, S., A. B. Rabson, J. F. Germino, M. A. Gallo, and Y. Tian. 2001. Mechanism of suppression of

cytochrome P-450 1A1 expression by tumor necrosis factor-alpha and lipopolysaccharide. J Biol Chem 

276:39638-44. 

7. Tian, Y., A. B. Rabson, and M. A. Gallo. 2002. Ah receptor and NF-kappaB interactions: mechanisms 

and physiological implications. Chem Biol Interact 141:97-115. 

8. Tian, Y., S. Ke, M. Chen, and T. Sheng, Interactions between the Ah receptor and P-TEFb: sequential 

recruitment of transcription factors and differential phosphorylation of C-terminal domain of RNA 

polymerase II at cyp1a1 promoter. J Biol Chem. 278:44041-44048, 2003. 

9. Gu, X., Ke, S., Liu, D., Sheng, T., Thomas, P.E., Rabson, A.B., Gallo, M.A., Xie, W., and Tian, Y. (2006). 

Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of 

cytochrome P-450 3A4 by proinflammatory agents. J Biol Chem 281, 17882-17889. 

10. Chandra, D., Bratton, S.B., Person, M.D., Tian, Y., Martin, A.G., Ayres, M., Fearnhead, H.O., Gandhi, V., 

and Tang, D.G. (2006). Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome 

C and inhibiting apoptosome. Cell 125, 1333-1346. 

11. Xie, W. and Tian, Y.(2006) Xenobiotic receptor meets NF-B, a collision on the GI track. Cell 

Metabolism 4, 1-2. 

12. Christine Naspinski, Xinsheng Gu, Guo-Dong Zhou, Wen Xie, KC Donnelly, and Yanan Tian. Pregnane X 

receptor protects HepG2 cells from BaP-induced DNA damage (in preparation). 

13. Hollie I. Swanson, S. D. K., Soma S. Ray, Martin Hoagland, Earl D. Thompson, Xinyu Zheng, and Yanan 

Tian (2005). Experimental Approaches for the Study of Cytochrome P450 Gene Regulation. Drug 

Metabolism and Transport: Molecular Methods and Mechanisms. L. H. Lash, Humana Press: 17-44.




NAME 

Abbott, Louise C. 



Associate Professor 



29. Positions and Honors 

DEGREE 


YEAR(s) 


Whitman College, Walla Walla, WA B.A. 1975 Biology 

University of Washington, Seattle, WA Ph.D. 1982 Developmental Biology 

Washington State University, Pullman, WA D.V.M. 1988 Veterinary Medicine 


1982 -1983 Postdoctoral Research Associate, Department of Veterinary & Comparative Anatomy, 

Pharmacology Physiology, College of Veterinary Medicine, Washington State University, 

Pullman, WA 

1983 -1988 Assistant Professor (70% appointment, non-tenure track; 50% student), Department of 

Veterinary & Comparative Anatomy, Pharmacology & Physiology, College of Veterinary 

Medicine, Washington State University 

1988 -1994 Assistant Professor, Department of Veterinary Biosciences, College of Veterinary Medicine, 

University of Illinois at U-C, Urbana, IL 

1988 -1994 Faculty member, Neuroscience Program, University of Illinois at U-C, Urbana, IL 

1994 -1999 Assistant Professor, Department of Veterinary Anatomy & Public Health, College of Veterinary 

Medicine, Texas A&M University, College Station, TX 

1995 - Faculty member, Neuroscience Program &Toxicology Program, Texas A&M University 

1999 - Associate Professor, Department of Veterinary Anatomy & Public Health, College of Veterinary 

Medicine, Texas A&M University 


1994 Fulbright Research Scholarship (Paris, France) 

2001 - 2006 Member, BDCN-1 AD HOC NIH Study Section (Ad Hoc member, CND Study section 

[formerly BDCN-1]) 

Honors 

1975 Phi Beta Kappa Honor Society; Graduated magna cum laude, with Honors in major study (B.A.) 

1977 - 1981 Developmental Biology Graduate Training Program Fellowship (Univ. of Washington) 

1985 Member, Phi Zeta Honor Society 

1988 Seattle-King County Veterinary Medical Association Scholarship; Graduated cum laude (D.V.M.) 

1989 Arnold O. Beckman Research Award (Univ. of Illinois) 

1990 SAVMA Veterinary Medical Teaching Excellence Award in Basic Sciences (Univ. of Illinois) 

1993 College of Veterinary Medicine Teaching Award (Univ. of Illinois) 

1989 - 1993 Listed on Incomplete List of Teachers Ranked Excellent (Univ. of Illinois) 

1997 - 1998 Montague Center for Teaching Excellence Scholar (Texas A&M University) 

1999 Samuel F. Scheidy Memorial Award from the Veterinary Medical Foundation (for Research 

Excellence) 

B. Selected peer-reviewed publications (42 total) 

Abbott, L.C. and D. M. Jacobowitz. 1999. Developmental expression of calretinin immunoreactivity in the 

thalamic eminence of the fetal mouse. International J. of Devel. Neurosci. 17(4):331-345. 

Abbott, L.C. and C. Sotelo. 2000. Ultrastructural analysis of catecholaminergic innervation in weaver and 

normal mouse cerebellar cortices. J. Comp. Neurology 426:316-329.

Dove, L.S., Nahm, S.S., Murchison, D., Abbott, L.C. and W.H. Griffith. 2000. Altered calcium homeostasis in 

cerebellar Purkinje cells of leaner mutant mice. J. Neurophysiology 84:513-524. 

Murchison, D., Dove, L.S., Abbott, L.C. and W.H. Griffith. 2002. Homeostatic compensation maintains C 2+ 

signaling functions in Purkinje neurons in the leaner mutant mouse. The Cerebellum 1(2): 30-35. 

Nahm, S., D. Tomlinson and L.C. Abbott. 2002. Decreased calretinin expression in cerebellar granule cells in 

the leaner mouse. Journal of Neurobiology 51:313-322. 

Guyer, C.L., G. Stoica, J.E. Womak, R.W.Storts, J.N. Derr, and L.C. Abbott. 2002. A line of Berlin Druckerey 

IV rats proposed as a new model for human hereditary ataxia. In vivo 16:255-264. 

Coates, J.R., D.P. O’Brien, K.L. Kline, R.W. Storts, G.C. Johnson, G.D. Shelton, E.E. Patterson,and L.C. 

Abbott. 2002. Neonatal Cerebellar Ataxia in Coton de Tulear Dogs. J. Vet. Internal Medicine 16:680-689. 

Cicale, M., A. Ambesi-Impiombato, V. Cimini, G. Fiore, G. Muscettola, L.C. Abbott and A. de Bartolomeis. 

2002.Decreased gene expression of calretinin and ryanodine receptor type 1 in tottering mice.Brain Res. 

Bul.59(1):53-58. 

Hsiao, S.-H., Parrish, A.R., Nahm, S.S., Abbott, L.C., McCool, B.A., and G.D. Frye. 2002. Effects of early 

postnatal ethanol intubation on GABAergic synaptic proteins. Devel. Brain Research 138:177-185. 

Rhyu, I.J., S. Nahm, S. J. Hwang, H. Kim, Y.S. Suh, S.I. Oda, T.C. Frank and L.C. Abbott. 2003. Altered neuronal 

NOS expression in the cerebellum of calcium channel mutant mice. Brain Research. 977:129-140. 

Frank, T.C., M. Nunley, R. Renaldo, and L.C. Abbott. 2003. Fluoro-Jade identification of cerebellar granule cell 

and Purkinje cell death in the 1A calcium ion channel mutant mouse, leaner. Neuroscience. 118:667-680. 

Nahm, S.-S., Frank, T.C., Browning, M., Sepulvado, J., Hiney, J.K., and L.C. Abbott. 2003. Insulin-like growth 

factor-I improves cerebellar dysfunction but does not prevent cerebellar neurodegeneration in the calcium 

channel mutant mouse, leaner. Neurobiology of Disease. 14:157-165. 

Nahm, S.-S. and L.C. Abbott. 2004. Neuronal nitric oxide synthase expression in cerebellar mutant mice. The 

Cerebellum, 3(3): 141-151. 

Lau, F.C., T.C. Frank, S.S. Nahm, G. Stoica and L.C. Abbott. 2004. Postnatal apoptosis in cerebellar granule 

cells of homozygous leaner (tg la /tg la ) mice. Neurotoxicity Research. 6(4):267-280. 

Nahm, S.-S., K.-Y. Jung, M.K. Enger, W.H. Griffith, L.C. Abbott. 2004. Differential expression of T-type calcium 

channels in P/Q-type calcium channel mutant mice with ataxia and absence epilepsy. Journal of 

Neurobiology. 62(3):352-60 

McCormick, B.H., D.M. Mayerich, B.L. Busse, Z. Melek, W. Koh, L.C. Abbott, Y. Choe J. Keyser, E.-J. Kim. 

2005. The whole mouse brain: The spatial distribution and morphology of its neurons. Microsc. Microanal 

11(Suppl2):640-641. 

McCormick, B.H., B.L. Busse, D.M. Mayerich, L.C. Abbott, Y. Choe J. Keyser, S.J. Smith, W. Denk. 2005. 

Biologically accurate modeling of mouse brain requires biologically accurate networks. Microsc. Microanal 

11(Suppl2):66-67. 

Bellum, S., K. Thuett, R. Taylor and L.C. Abbott. 2006. Assessment of tissue concentrations of mercury in 

mouse brain tissue using different routes of administration of methylmercury and different tissue 

preparations. Toxicology Mechanisms and Methods. In Press. 

Frank-Cannon, T.C, D.R. Zeve and L.C. Abbott. 2006. Developmental expression of neuronal nitric oxide 

synthase in P/Q-type voltage-gated calcium ion channel mutant mice, leaner and tottering. Brain Research. 

2005 Dec 13; [Epub ahead of print]. 

Etheredge, J.A., D. Murchison, L.C. Abbott and W.H. Griffith. 2006. Functional compensation by other voltage 

gated Ca 2+ channels in mouse basal forebrain neurons with Ca v 2.1 mutations. Brain Research. 2005 Dec 

16; [Epub ahead of print]. 

Bellum, S., K. Thuett and L.C. Abbott. 2006. Coordination deficits induced in young adult mice treated with 

methylmercury. International Journal of Toxicology. Accepted pending revisions. 

Textbooks: Jacobowitz, D.M. and L.C. Abbott. 1997. Chemoarchitectonic Atlas of the Developing Mouse 

Brain. CRC Press, Boca Raton, FL.




NAME 

Allred, Clinton D. 






DEGREE 


YEAR(s) 


University of Georgia, Athens, GA B.S.A. 1997 Animal Sciences 

University of Illinois, Urbana, IL Ph.D. 2002 Nutritional Sciences 

University of Kentucky, Lexington, KY Post-doc 2002-2006 Molec. & Biomed. Pharm. 

A. Professional Experience 

2002-2006 Postdoctoral Fellow, Department of Molecular and Biomedical Pharmacology, College of 

Medicine, University of Kentucky, Lexington, KY 

2006-Present Assistant Professor, Department of Nutrition and Food Science and Interdisciplinary Faculty 

of Toxicology, Texas A&M University, College Station, TX 


2005 Endocrine Society Travel Grant; Abstract selected by the Endocrine Society Media Advisory 

Committee to appear in the Research Summaries Book at the Endocrine Society’s Annual 

Meeting 

2003 David H. Baker Nutrition Scholar Award 

2001-2002 University of Illinois Fellowship 

2001 Division of Nutritional Sciences Student Research Award 

2000-2003 Environmental Toxicology Scholar Fellowship 

2000 Invited to join Gamma Sigma Delta Agriculture Honor Society 

2000 Society of Toxicology Graduate Student Travel Award Error! Bookmark not defined. 

2000 Winner of Food Safety Specialty Section Graduate Student Award at SOT Error! Bookmark 

not defined. 

2000 Midwest Society of Toxicology Travel Award 

B. SELECTED PEER REVIEWED PUBLICATIONS: 

Helferich, W.G., Allred, C.D. and Ju, Y.H. 2000. Dietary Estrogens and Antiestrogens. In Helferich, W.G. 

and Winter, C.K. (eds.) Food Toxicology. CRC Press, Boca Raton. (book chapter) 

Allred, C. D., Ju, Y.H., Allred, K. F., Chang, J., and Helferich, W. G. Dietary Genistin Stimulates Growth of 

Estrogen-Dependent Breast Cancer Similar to that Observed with Genistein. Carcinogenesis, 22: 

1667-1673. 2001. 

Allred, C. D., Allred, K. F., Ju, Y.H., Virant, S.M., and Helferich, W. G. Soy Diets Containing Varying 

Amounts of Genistein Stimulate Growth of Estrogen-dependent (MCF-7) Tumors in a Dose-dependent 

Manner. Cancer Research, 61: 5045-5050. 2001. 

Ju, Y.H., Allred, C.D., Allred, K.F., Karko, K.L., Doerge, D.R., and Heleferich, W.G. Physiological 

Concentrations of Dietary Genistein Stimulate Growth of Estrogen-dependent Human Breast Cancer 

(MCF-7) Tumor Implanted in Athymic Nude Mice in a Dose-dependent Manner. Journal of Nutrition, 

131: 2957-2962. 2001.

Ju, Y.H., Doerge, D.R., Allred, K.F., Allred, C.D., and Helferich, W.G. Dietary Genistein Negates the 

Inhibitory Effect of Tamoxifen on Growth of Estrogen-dependent Human Breast Cancer (MCF-7). 

Cancer Research, 62: 2474-2477. 2002. 

Yellayi, S., Naaz, A., Szewczykowski, M.A., Sato, T., Woods, J.A., Chang, J., Serge, M., Allred, C.D., 

Helferich, W.G., and Cooke, P.S. The phytoestrogen genistein induces thymic and immune changes: a 

human health concern? Proc. Natl. Acad. Sci., 99: 7616-7621, 2002. 

Allred, C. D., Allred, K. F., Ju, Y. H., Doerge, D.R., Schantz, S., Korol, D., and Helferich, W. G. Dietary 

genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy 

of Sprague-Dawley rats. Carcinogenesis, 25 (2): 211-218. 2004. 

Allred, C. D., Allred, K. F., Ju, Y. H., Goeppinger, T., Doerge, D. R., and Helferich, W. G. Processing 

influences growth of estrogen-dependent breast cancer tumors. Carcinogenesis, 25 (9): 1649-1657. 

2004. 

Allred, C.D. and Kilgore, M.W. Selective Activation of PPARγ in Breast, Colon, and Lung Cancer Cell 

Lines. Molecular and Cellular Endocrinology. 235: 21-29. 2005. 

Allred, C.D., Twaddle, N.C., Allred, K.F., Goeppinger, T.S., Churchwell, M.I., Ju, Y.H., Helferich, W.G., and 

Doerge, D.R. Soy processing affects metabolism and disposition of dietary isoflavones in 

ovariectomized balb/c mice. Journal of Agriculture and Food Chemistry. 53 (22): 8542-8550. 2005. 

Ju, Y.H., Allred, K.F., Allred, C.D., and Heleferich, W.G. Genistein stimulates growth of human breast 

cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations. 

Carcinogenesis. 27: 1292-1299. 

Allred, C.D., Talbert, D.R., and Kilgore, M.W. Defining the Molecular Actions of Eicosapentaenoic Acid in 

Colon Cancer: Modulation of Peroxisome Proliferator-Activated Receptor Gamma. Accepted for 

publication in Molecular and Cellular Endocrinology. 

Wang, X., Allred, C.D., Southard, R.C., Wilson, M.E., and Kilgore, M.W. Myc-Associated Zinc Finger 

Protein Mediates the Overexpression of PPAR gamma in Human Breast Cancer Cells by Driving 

Promoter Switching. Submitted for publication in Cancer Research. 

Talbert, D.R., Allred, C.D., and Kilgore, M.W. Rosiglitazone Activates ERα and PPARγ Altering Their 

Crosstalk and Effect on Proliferation in Cancer Cells. Submitted for publication in Journal of Molecular 

Endocrinology.


Provide the following information for the key personnel in the order listed on Form Page 2. 


NAME 

Autenrieth, Robin L. 





DEGREE 


YEAR(s) 


University of Maryland B.S. 1977 Biological Sciences 

Clarkson College of Technology M.S. 1971 Environmental 

Clarkson University Ph.D. 1986 Environmental 

A. Positions and Emplyment 

1977 Research Assistant, University of Maryland 

1977-1979 Environmental Chemist/Biologist, Hess Oil Virgin Islands Corporation, Professor, Dept. of Civil 

1979-1983 Research Assistant, Clarkson College of Technology 

1983-1985 Instructor, Clarkson College of Technology 

1986-1993 Assistant Professor, Dept. of Civil Engineering, Texas A&M University 

1993-2000 Associate Professor, Dept. of Civil Engineering, Texas A&M University 

2000- Professor, Dept. of Civil Engineering, Texas A&M University, Joint appointment in the Dept. of 

Environmental & Occupational Health, School of Rural Public Health 

Honors 

1991 Zachry Award for Excellence in Teaching 

1996 Way Cool Scientist, Bill Nye the Science Guy Trading Cards 

1996-1997 Texas Engineering Experiment Station Research Fellow 

2003-2004 Neely ‘52/Dow Chemical Fellow 

2004 Aldo Leopold Leadership Fellow, 2004 

2004 A.P. & Florence Wiley Professorship III 

B. Selected peer-reviewed publications 

Erica D. Bruce, Afraa A. Abusalih, Thomas J. McDonald, Robin L. Autenrieth, “Comparing Deterministic and 

Probabilistic Risk Assessments for Sites Contaminated by Polycyclic Aromatic Hydrocarbons (PAHs), J. 

Environ. Sci. Health, Part A, Vol. A42, No. 6 (2007). 

Nwaneshiudu, O., R. Autenrieth, T. McDonald, K. Donnelly, E. Degollado, A. Abusalih, “Risk of PAH exposure 

from ingested food: the Azerbaijan case study,” J. of Environmental Science and health, Part B, Vol. 

B42(2), (2007). 

Review of International (Non-U.S.) Technologies for Destruction of Recovered Chemical Warfare Materiel 

National Resaerch Council of the National Academies Committee on Review and Evaluation of 

International Technologies for the Destruction of Non-Stockpile Materiel Board on Army Science and 

Technology Division on Engineering and Physical Sciences The National Academies Press Washington, 

D.C. www.nap.edu 

Abraham, M. H., R. L. Autenrieth, and P. Dimitriou-Christidis, “The estimation of physicochemical properties of 

methyl and other alkyl naphthalenes,” Journal of Environmental Monitoring, 7(5): 445-449 (2005). 

Matson, C. W., G. Palatnikov, T. J. Mcdonald, R. L. Autenrieth,| K. C. Donnelly, T. A. Anderson, J. E. Canas, 

A. Islamzadeh and J. W. Bickham, “Patterns of Genotoxicity and Contaminant Exposure: evidence of 

Genomic Instability in the Marsh Frogs (Rana ridibunda) of Sumgayit, Azerbaijan,” Environmental 

Toxicology and Chemistry , (8):2055-64 (2005). 

Matson, C., Palatnikov, G., Islamzadeh, A., McDonald, T., Autenrieth, R., Donnelly, K.C., and Bickham, J., 

“Chromosomal damage in two species of aquatic turtles (Emys orbicularis and Mauremys caspica)

inhabiting contaminated sites in Azerbaijan,” Ecotoxicology , 14(5): 513-525 (2005). 

LaRiviere, D., Autenrieth, R., Bonner, J., “Redox dynamics of a tidally-influenced wetland on the San Jacinto 

River,” Estuaries, 27(2): 253-264 (2004). 

Simon, M.A., Bonner, J.S., Page, C.A., Townsend, R.T., Fuller, C.B., Mueller, D.C., and Autenrieth, R.L. 

“Evaluation of Two Commercial Bioaugmentation Products for Enhanced Removal of Petroleum from a 

Wetland”, Ecological Engineering, 22, pp. 263-277, 2004. 

Mills, M.A., Bonner, J.S., Page, C.A., and Autenrieth, R.L., “Bioremediation of an Experimental Oil Spill in a 

Wetland,” Marine Pollution Bulletin, 49(5-6), 425-435, 2004. 

Mills, M.A., Bonner, J.S., McDonald, T., Page, C. and Autenrieth, R.L., “Evaluation of Intrinsic Remediation of 

a Petroleum-Contaminated Wetland”, Marine Pollution Bulletin, 46(7), 887-899, 2003. 

Sterling, M., Bonner, J., Ernest, A., Page, C., and Autenrieth, R., “Chemical Dispersant Effectiveness Testing: 

Influence of Droplet Coalescence,” Marine Pollution Bulletin, Vol. 48(5-6), 969-977, 2004. 

Sterling, M., Bonner, J., Ernest, A., Page, C., and Autenrieth, R., “Characterizing Aquatic Particulate-Oil Flocs 

Using In-Situ Instruments, Marine Pollution Bulletin, 48, 533-542, 2004. 

Bae, B., I. Lee, Y., Kweon, K., Ko, S. Lee, Y. Ban, Y. Cho, R. Autenrieth, “Site Investigation and Remedial 

Study at Darakdae Artillary Shooting Range for Full Scale Phyto- and Bioremediation,” in In Situ and On- 

Site Bioremediation: Volume 6, B.C. V. Magar and M. Kelly (eds), Battelle Press, (2003). 

Sterling, M., Bonner, J., Page, C., Fuller, Ernest, A., and Autenrieth, R., “Partitioning of Crude Oil Polycyclic 

Aromatic Hydrocarbons in Aquatic Systems, Environmental Science and Technology, 48(37): 4429- 

4434, 2003. 

Dimitriou-Christidis, P, Harris, B., McDonald, T., Reese, E., and Autenrieth, R. “Estimation of aqueous 

solubility, octanol/water partition coefficient, vapor pressure, and Henry’s law constant of 20 methylated 

naphthalene compounds,” Chemosphere, 52: 869-881 (2003). 

LaRiviere, D., Autenrieth, R., Bonner, J., “Redox Dynamics During Recovery of an Oil-Impacted Estuarine 

Wetland,” Water Research, 37: 3307-3318 (2003) 

Mueller, D., Bonner, J., McDonald, S., Autenrieth, R., Donnelly, K.C., Lee, K., Doe, K., Anderson, J., “The Use 

of Toxicity Bioassays to Monitor the Recovery of Oiled Wetland Sediments,” Environmental Toxicology 

and Chemistry, 22(9): 1945-1955 (2003).




NAME 

Ball, Judith M. 






DEGREE 


YEAR(s) 


Southeastern Louisiana University, Hammond, LA B.S. 1974 

Medical Technology, 

Chemistry (minor) 

Louisiana State University, Baton Rouge, LA Ph.D. 1990 Biochemistry 

A. Positions and Honors. 


1975-1981 Medical Technologist (ASCP), Baton Rouge General Hospital, Department of Pathology, Baton 

Rouge, LA 

1981-1984 Research Associate III, State Diagnostic Virology Laboratory, Louisiana State University, Baton 

Rouge, LA 

1984-1990 Graduate Research Assistant, Department of Biochemistry, Louisiana State University 

1990-1991 Postdoc, University of Pittsburgh School of Medicine, Department of Biochemistry, Pittsburgh, 

PA 

1991-1993 Postdoc, University of Alabama at Birmingham, Department of Microbiology and Immunology, 

Birmingham, AL 

1994-1997 Research Associate, Baylor College of Medicine, Division of Molecular Virology, Houston, TX 

1997-2002 Assistant Professor, Department of Pathobiology, Texas A&M University, College 

Station, TX 

1998-2002 Assistant Professor, Joint appointment, Department of Medical Biochemistry and Genetics, 

Texas Health Science Center, Texas A&M University, College Station, TX 

1998-Present Director, Peptide Synthesis Core Facility, Texas A&M University 


2000-Present Member of Faculty of Genetics and Interdisciplinary Faculty of Virology, Texas A&M University 

2001-Present Member of Interdisciplinary Faculty of Toxicology, Texas A&M University, College Station, TX 

2002 Promotion to Associate Professor with tenure, Texas A&M University 

2003-Present Graduate Advisor, Department of Pathobiology, Texas A&M University 


1. Ball, J.M., Payne, S.L., Issel, C.J., and Montelaro, R.C. (1988). EIAV Genomic Organization: Further 

Characterization by Sequencing of cDNA and Purified Glycoproteins. Virology 165:601-605. 

2. Ball, J.M., Payne, S.L., Issel, C.J., and Montelaro, R.C. (1988). EIAV Genomic Organization: Further 

Characterization by Sequencing of cDNA and Purified Glycoproteins. Virology 165:601-605. 

3. Chon, Y.H., Ball, J.M., Dhruva, B., Issel, C.J., Montelaro, R.C., and Rushlow, K.E. (1991). Analysis of host 

immune responses to the transmembrane envelope glycoprotein (gp45) of equine infectious anemia virus: 

Localization of an immunodominant B-cell determinant. J Virol 65:1013-1018. 

4. Ball, J.M., Rushlow, K.E., Issel, C.J., and Montelaro, R.C. (1992). Detailed Mapping of the Antigenicity 

of the Surface Unit Glycoprotein of Equine Infectious Anemia Virus by Using Synthetic Peptide 

Strategies. J. Virol. 66:732-742. 

5. Ball, J.M., Henry, N.L., Montelaro, R.C., and Newman, M.J. (1994) A Versatile Peptide-based ELISA for 

Identifying Antibody Epitopes, Journal of Immunol. Methods 171:37-44. 

6. Ball, J.M., Moldeveanu, Z., Melsen, L, Kowalski, P., Jackson, S., Mulligan, M., Mestecky, J., and 

Compans, R. (1995). Characterization of a polarized human endometrial cell line which binds and 

transports pIgA. In Vitro 31:196-206. 

7. Gallaher, W.R., Ball, J.M., Garry, R.F., and Montelaro, R.C. (1995). A Structural Model for the Surface

Unit Glycoprotein of HIV. gp120, and Other Retroviruses. AIDS and Other Hum. Retrovir. 11:191-202. 

8. Ball, J.M., Estes, M.K., Hardy, M.E., Conner, M.E., Opekun, A.A., and Graham, D.Y. (1996). 

Recombinant Norwalk virus-like particles as an oral vaccine. Arch. of Virol. 12:243-249. 

9. Ball, J.M., Tian, P., Zeng, C., Morris, A.P., and Estes, M.K. (1996) Age-Dependent Diarrhea is Induced 

by a Rotavirus Nonstructural Glycoprotein. Science 272:101-104. 

10. Mason, H.S., Ball, J.M., Shi, J.J., Estes, M.K., and Arntzen, C.J. (1996). Expression of Norwalk Virus 

Capsid Protein in Transgenic Tobacco and Potato and its Oral Immunogenicity in Mice. PNAS, USA 

93:5335-5340. 

11. Ball, J.M., Mulligan, M., and Compans, R.W. (1997). Basolateral sorting of the Human 

Immunodeficiency Virus 2 and Simian Immunodeficiency Virus in Polarized Epithelial Cells: Role of the 

Cytoplasmic Domain. AIDS Res. and Hum. Retrovir. 13:665-675. 

12. Dong, Y., Zeng, C.Q.-Y., Ball, J.M., Estes, M.K., and Morris, A.P. (1997). The rotavirus enterotoxin 

NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated 

inositol 1,4,5-triphosphate production. PNAS, USA 94:3960-3965. 

13. Estes, M.K., Ball, J.M., Crawford, S.E., O’Neal, C.M., Opekun, A.A., Graham, D.Y., and Conner, M.E. 

(1997). Virus-Like Particle Vaccines for Mucosal Immunization, Adv. in Exp. Med. & Biol. 412:387-395. 

14. Ball, J.M., Hardy, M.E., Atmar, R., Conner, M.E., and Estes, M.K. (1998). Oral Immunization with 

Recombinant Virus-Like Particles Induces a Systemic and Mucosal Immune Response in Mice. J. Virol. 

72:1345-1353. 

15. Ball, J.M., Graham, D.Y., Opekun, A.R., Gilger, M.A., Guerroro, R.A., and Estes, M.K. (1999). 

Recombinant Norwalk virus-like particles given orally to volunteers: Phase I study. Gastroenterology 

117:40-48. 

16. Morris, A.P., Scott, J.K., Ball, J.M., Zeng, C.Q.-Y., O’Neal, W.K., and Estes, M.K. (1999). The rotaviral 

enterotoxin NSP4 elicits age-dependent diarrhea and calcium-mediated iodide influx into intestinal 

crypts of cystic fibrosis mice. Am. J. Physiol. 277:G431-G444. 

17. Zhang, M., Zeng, C.Q.-Y., Dong, Y., Ball, J.M., Saif, L.J., Morris, A.P., and Estes, M.K. (1998). 

Mutations in rotavirus nonstructural glycoprotein NSP4 are associated with altered virus virulence. J. 

Virol. 72:3666-3672. 

18. Swaggerty, C., Frolov, A., McArthur, M., Cox, V., Tong, S., Schroeder, F., Compans, R., and Ball, J.M. 

(2000). Simian Immunodeficiency Virus (SIV) surface unit glycoprotein contains an enterotoxic domain. 

Virol. 277:250-261. 

19. Estes, M.K., Ball, J.M., Guerrero, R.A., Opekun, A.R., Gilger, M.A., Pacheco, S.S., and Graham, D.Y. 

(2000). Norwalk virus vaccines: Challenges and vaccines. J. Inf. Dis. 181:S367-S373. 

20. Huang, H., Schroeder, F., Zeng, C., Estes, M.K., Schoer, J.K., and Ball, J.M. (2001). Membrane 

interactions of novel viral enterotoxin: Rotavirus nonstructural glycoprotein NSP4. Biochemistry 

38:13231-13243. 

21. Holman, P.J., Hsieh, M., Nix, J., Bendele, K., Wagner, G.G., and Ball, J.M. (2002). Evaluation of a 

cysteine protease as a drug target: Characterization of an enzyme conserved among Babesia equi 

isolates. Mol. Biochem. Parasitol. 119:295-300. 

22. Huang, H., Gallegos, A.M., Ball, J.M., and Schroeder, F. (2002). Role of sterol carrier protein-2 N- 

terminal membrane binding domain in sterol transfer. Biochemistry 41:12149-12162. 

23. Schroeder,F., Zhou, M., Swaggerty, C.L., Atshaves, B.P., Petrescu, A.D., Storey, S., Martin, G.G., 

Huang, H., Helmkamp, G.M., and Ball, J.M. (2003). Sterol carrier protein-2 functions in 

phosphatidylinositol transfer and signaling, Biochemistry 42:3189-3202. 

24. Lim, W.-S., Edwards, J.F., Boyd, N.K., Payne, S.L., and Ball, J.M. (2003). Simultaneous quantitation of 

equine cytokine mRNAs using a multi-probe ribonuclease protection assay. Vet.Immunol. and 

Immunopath. 91:45-51. 

25. Boyd, N.K., Cohen, N.D., Lim, W.-S., Martens, R.J., Chaffin, M.K., and Ball, J.M. (2003). Temporal 

changes in cytokine expression of foals during the first month of life. Vet.Immunol. and Immunopath. 

92:75-85. 

26. Parr, R. D. and Ball, J.M. (2003) New donor vector for generation of histidine-tagged fusion proteins 

using the Gateway Cloning System. Plasmid 49:79-83.




NAME 

Barr, Amy Catherine 


NA 


Veterinary Toxicologist 



DEGREE 


YEAR(s) 


Centre College, Danville, KY BS 1986 Biochemistry/ Mol Bio 

Texas A&M University, College Station, TX PhD 1996 Toxicology 

A. Positions and Honors. List in chronological order previous positions, concluding with your present 

position. List any honors. Include present membership on any Federal Government public advisory 

committee. 


Summer 1983 Junior Research Fellow, Pharmacokinetics, Univ. of Tennessee Health Science Center 

Summer 1984 Junior Research Fellow, Pharmacokinetics, Univ. of Tennessee Health Science Center 

Summer 1985 Summer Research Fellow, Biochemistry, Univ. of Louisville JG Brown Cancer Center 

1987 Technician I, Medical Biochemistry/Genetics, Texas A&M University 

1988-1989 Purchasing Representative and Protein Chemist, Biophor Corp., College Station, TX 

1989-1991 Technician II, Medical Biochemistry/Genetics, Texas A&M University 

1991-1997 Diagnostic Laboratory Supervisor, Toxicology, Texas Veterinary Medical Diagnostic 

Laboratory (TVMDL) 

1997-2001 Assistant Toxicologist, Toxicology, TVMDL 

2001- Veterinary Toxicologist, Toxicology, TVMDL 


1986-1997 Member, American Chemical Society 

1986-2002 Member, American Association for the Advancement of Science 

1992- Study Director, Effects of Fenoxycarb in Sheep, Reproductive and Kinetic, TVMDL 

1993-2004 Member, Association of Official Analytical Chemists, International (now AOACi) 

1993- Member, American Association of Veterinary Laboratory Diagnosticians (AAVLD) 

1998 Field Guide, Toxic Plant Day, 5 th Intl Symposium on Poisonous Plants, San Angelo, TX 

1998- Assistant Professor, Adjunct, Veterinary Anatomy/Public Health (Veterinary Integrative 

Biosciences), Texas A&M University 

1998-1999 Scientific Program Chair, World Association of Veterinary Laboratory Diagnosticians IX 

Symposium 

1999- Member, American Academy of Veterinary and Comparative Toxicology (AAVCT) 

1999-2001 Vice President, AAVCT 

1995-1998 Steering Committee, Veterinary Analytical Toxicology, AAVLD 

1995-2001 Mycotoxin Committee, AAVLD 

1998 Quality Assurance Advisor for External Contracts, TVMDL 

1998-2003 AAVCT liaison to Veterinary Analytical Toxicology Committee, AAVLD 

1999-2001 Vice President, AAVCT 

2000- Diplomate, American Board of Toxicology 

2001-2003 President, AAVCT

2003-2005 Past President AAVCT 

2003-2005 Steering Committee, Veterinary Analytical Toxicology, AAVLD 

2003- State of Texas Inter-Agency Aflatoxin/Mycotoxin Task Force 

2004- Member, Integrated Faculty of Toxicology, Texas A&M University 

2004- Councilor, AAVCT 

2004- Co-Chair, Steering Committee, Veterinary Analytical Toxicology, AAVLD 

2004- Reviewer for Toxicology Manuscripts, Journal of Vet Diagnostic Investigation 

2005- Co-Chair, Approved Methods Committee, AAVLD 

2005- Diplomate, American Board of Toxicology, successful 5 th -year re-certification 

B. Selected peer-reviewed publications (in chronological order). Do not include publications 

submitted or in preparation. 

1. Buice RG, Gurley BJ, Sidhu P, Thais AC. Effects of total body irradiation followed by bone marrow 

transplantation on the disposition kinetics of methotrexate in the rat. Res Comm Chem Path Pharm 

1985; 47:123-132. 

2. Sato N, Hyder SM, Chang L, Thais AC, Whitliff JL. Interaction of estrogen receptor isoforms with 

immobilized monoclonal antibodies. J Chrom 1986; 359:475-487. 

3. Barr AC, Abbitt B, Fiske RA, Jaques JT, Maynard HR, Reagor JC. Reproductive effects of fenoxycarb in 

sheep. J Vet Diagn Invest 1997; 9:401-406. 

4. Barr AC, Wigle WL, Flory W, Alldredge BE, Reagor JC. Cantharidin poisoning of emu chicks by 

ingestion of Pyrota insulate. J Vet Diagn Invest 1998; 10:77-79.




NAME 

Bernstein, Lori R. 






DEGREE 


YEAR(s) 


Harvard University, Cambridge, MA B.A. 1981 Biochemical Sciences 

The Johns Hopkins University, Baltimore, MD Ph.D. 1989 Biochemistry/Biology 

National Institutes of Health, Frederick, MD, and 

Bethesda, MD 

postdoc 1990-1995 Gene regulation and 

molecular carcinogenesis 



1981 Honor’s Undergraduate Thesis Research in Angiogenesis and Wound Healing with Drs. 

Judah M. Folkman and Bruce R. Zetter, Harvard Medical School 

1983-1989 Graduate student, Department of Biology, The Johns Hopkins University, Baltimore, MD 

campus (1983-1987), and Cell Biology Section, with Dr. Nancy Colburn, National Cancer 

Institute, Frederick Cancer Research and Development Center, 1987-1989 

1990-1992 Postdoctoral Fellow with Nancy Colburn, Ph.D., Chief, Cancer Prevention, NCI Frederick, MD 

1993-1994 Postdoctoral Fellow with Dr. Lance Liotta, Laboratory of Pathology, NCI, NIH, Bethesda, MD 

1995-1996 Visiting Scientist, with Dr. Dan Longo, Biological Responses Modifiers Prog., Frederick, MD 

1996-present Assistant Professor, Department of Molecular and Cellular Medicine, Texas A&M University 

System Health Science Center, College Station, TX 

1997-present Faculty of Toxicology, Texas A&M University 

1997-present Faculty of Genetics, Texas A&M University 

2000-present Member, Center for Environmental and Rural Health (CERH), Texas A&M University 


1983-1987 NIH Training Grant, John Hopkins University 

1987-1989 Predoctoral Intramural Research Training Award, National Institutes of Health 

1990-1994 Postdoctoral Intramural Research Training Award, National Cancer Institute 

1995 Cold Spring Harbor Course-Advanced Cloning and Expression of Eukaryotic Genes, with 

Travel Award 

1997 Chair, Symposium on “DNA Binding Proteins in Regulation of Gene Expression and 

Genomic Stability,” 9th International Meeting on Genes, Gene Families, and Isozymes, 

San Antonio, TX 

2002 Keynote speaker for Annual International Conference: American Academy of Anti Aging 

Medicine, “Genetic Instability and its Implications on an Aging Population.” 

2002 Keynote speaker for general session, American Academy of Anti-Aging Medicine, 

Chicago, June 1, 2002 

Ad Hoc Reviewer: Gene, Molecular Carcinogenesis, International Journal of Cancer, Molecular Cancer 

Research, and Cytokine 

Member: American Association for Cancer Research (AACR); ASBMB (FASEB) 

Honors 

1977-1981 Harvard University Dean’s List 

1981 Aggasiz Award, Radcliffe College 

1981 Magna Cum Laude in Biochemical Sciences, Harvard


Bernstein, L.R., and Colburn, N.H. AP-1/jun Function is Differentially Induced in Promotion Sensitive and 

Resistant JB6 Cells. Science 244:566-569, 1989. 

Bernstein, L.R., Ben-Ari, E.T., Simek, S.L., and Colburn, N.H. Gene regulation and genetic susceptibility to 

neoplastic transformation: AP-1 and p80 expression in JB6 cells. Environ. Health Perspec, 93:111-119, 

1991. 

Ben-Ari, E.T., Bernstein, L.R., and Colburn, N.H. Differential c-jun Expression in Response to Tumor 

Promoters in JB6 Cells Sensitive or Resistant to Neoplastic Transformation. Molecular Carcinogenesis 

5, 62-74. 1992. 

Bernstein, L.R., Bravo, R., and Colburn, N.H. 12-0-Tetradecanoylphorbol-13-acetate-Induced Levels of AP-1 

Proteins: A 46 kDa Protein Immunoprecipitated by anti Fra-1 and Induced in Promotion-Resistant but 

Not Promotion-sensitive JB6 Cells. Molecular Carcinogenesis 6:221-229, 1992. 

Bernstein, L.R., and Liotta, L.A. Molecular Mediators of Interactions with Extracellular Matrix Components in 

Metastasis and Angiogenesis, Current Opinion in Oncology 6, 1994. 

Bernstein, L.R., Ferris, D.K., Colburn, N.H., and Sobel, M.E. A family of mitogen-activated protein kinaserelated 

proteins interacts in vivo with activator protein-1 transcription factor. Journal of Biological 

Chemistry 269, Communication, 9401-9404, 1994. 

Watts, B., Ben-Ari, E.T., Bernstein, L.R., Birrer, M.J., and Colburn, N.H. C-jun and Multistage Carcinogenesis: 

association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in 

mouse JB6 cells sensitive to tumor promoter-induced transformation. Molecular Carcinogenesis, 13:27- 

36, 1995. 

Bernstein, L.R, Walker, S. E., Tumor promotion resistant cells are deficient in AP-1 DNA binding, Jun D DNA 

binding and Jun D expression and form different AP-1-DNA complexes than promotion sensitive cells, 

Biochimica et Biophysica Acta 1489:263-280, 1999. 

Nathan, I., Dizdaroglu, M. Bernstein, L.R., Junker, U., Chong Lee, C.K. Muegge K. and Durum, S.K. Tumor 

Necrosis Factor and Anti Fas Stimulation Induce Oxidative DNA Damage in Human U937 cells, 

Cytokine 12:881-887, 2000. 

Kumar, N.V., and Bernstein, L.R., Screening of a protein expression library by enhanced chemiluminescence 

detection. Biotechniques 29:418-423, 2000. 

Kumar, N.V., and Bernstein, L.R., Ten ERK-related Proteins in three distinct classes bind AP-1 proteins and/or 

AP-1 DNA. Journal of Biological Chemistry 276:32362-72, 2001. 

Kumar, N.V., and Bernstein, L.R., A New Analytical Scale DNA Affinity Binding Assay for Analyses of Specific 

Protein-DNA Interactions Analytical Biochemistry 299:203-210, 2001. 

Twizere, J.C., Kruys, V., Lefebvre, L., Vanderplasschen, A., Collete, D., Debacq, C., Lai, W.S., Jauniaux, J.C., 

Bernstein, L.R., Semmes, O.J., Burny, A., Blackshear, P.J., Kettmann, R., Willems, L. Interaction of 

retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression. 

J. Natl. Cancer Inst. 95:1846-59, 2003. 

Samuel, S. and Bernstein, L.R. Adhesion, migration, transcriptional, interferon-, and other signaling molecules 

newly implicated in susceptibility and resistance to neoplastic transformation by cDNA microarray 

analyses. Molecular Carcinogenesis, 39:34- 60, 2004. 

Samuel, S., Twizere, J-C., and Bernstein, L.R. YB-1 represses AP1-dependent gene transactivation and 

interacts with an AP-1 DNA sequence. Biochemical Journal, 388:921-8, 2005. 

Samuel, S., Beifuss, K.K., and Bernstein, L.R. YB-1 Binds to the AP-1 Site in the MMP-13 Promoter and 

Represses MMP-13 Transactivation and mRNA expression. Biochemical Journal, submitted and under 

revision for resubmission. 

Twizere, J-C., Samuel, S., and Bernstein, L.R. Nucleolin binds specifically to an AP-1 DNA sequence and 

represses AP1-dependent transactivation and mRNA expression of the matrix metalloproteinase-13 

gene, Molecular Carcinogenesis, submitted.


Provide the following information for the key personnel in the order listed for Form Page 2. 

Follow the sample format for each person. DO NOT EXCEED FOUR PAGES. 

NAME Gerald R. Bratton POSITION TITLE Professor 

EDUCATION (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) 


DEGREE 


YEAR(s) 


Texas A&M University, College Station, TX 




BS 

DVM 

MS 

PhD 

1965 

1966 

1970 

1977 

Veterinary Science 


Veterinary Anatomy 

Veterinary Anatomy 

EMPLOYMENT 

1966-1970 Instructor, Department of Veterinary Anatomy, Texas A&M University, College Station, Texas 

1971-1975 Assistant Professor, Department of Veterinary Anatomy, Texas A&M University, College 

Station, Texas 

1975-1981 Associate Professor, Department of Animal Science, College of Veterinary Medicine, 

University of Tennessee, Knoxville, Tennessee 

1981-1982 Professor, Department of Animal Science, College of Veterinary Medicine, University of 

Tennessee, Knoxville, Tennessee 

1982-1983 Professor, Department of Veterinary Anatomy, Texas A&M University, College Station, Texas 

1983-1998 Professor and Head, Department of Veterinary Anatomy and Public Health, Texas A&M 

University, College Station, Texas 

1987-Present Member of Toxicology Faculty, Texas A&M University, College Station, Texas 

1985-Present Clinical Professor of Neurology, Texas Veterinary Medical Center, Veterinary Teaching 

Hospital, College Station, Texas 

1988-Present Member of Neuroscience Faculty, Texas A&M University, College Station, Texas 

1998-Present Professor, Department of Veterinary Integrative Biosciences, Texas A&M University, College 

Station, Texas 

2000-Present Co-Director, TAMU, Trace Element Research Laboratory 

2005-Present Head, Department of Pathobiology 

HONORS AND AWARDS 

Norden Distinguished Teaching Award, University of Tennessee, 1977 

Student Chapter AVMA Teaching Award, University of Tennessee, 1978 

Texas Veterinary Medical Association Research Award, 1986 

Former Students Association Distinguished Achievement Award for Administration, 1992 

John H. Milliff Award for Teaching, 2000 

Former Students Association Distinguished Achievement Award for Teaching College Level, 2000 

Texas Veterinary Medical Association Award in Teaching, 2002 

Wiley Professorship, 2001 

Norden Distinguished Teaching Award, Texas A&M University, 2003 

Former Students Association Distinguished Achievement Award for Teaching University Level, 2003 

AAVA Natoinal Outstanding Anatomist of the Year, 2005 

PUBLICATIONS (Selected from a total of 93) 

Woshner, V.M., O=Hara, T.M., Eurell, J.A., Wallig, M.A., Bratton, G.R., Suydam, R.S., and Beasley,V.R. 

Distribution of Inorganic Mercury in Liver and Kidney of Beluga and Bowhead Whales, through 

Autometallographic Development of Light Microscopic Tissue Sections. Toxicologic Pathology. 

30(2):209-215, 2002. 

Smith, K.R., Nation, J.R., and Bratton, G.R. The Effects of Developmental Cadmium Exposure on Morphine 

Sensitization and Challenge with Selective D-1 and D-2 Antagonists. Pharmacology, Biochemistry, and 

Behaviour. 72:581-590, 2002. 

Dearth, R.K., Hiney, J.K., Srivastava, V., Burdick, S., Bratton, G.R., and Dees, W.L. Effects of Lead (Pb)

Exposure During Gestation and Lactation on Female Pubertal Development in the Rat. Reproductive 

Toxicology. 16(4):343-352, 2002. 

O’Hara, T.M., Woshner, V.M., and Bratton, G.R.. Inorganic Pollutants in Arctic Marine Mammals. J.G. Vos, 

G.D. Bossart, M. Fournier, and T.J. O=Shea, Eds. Toxicology of Marine Mammals. Taylor & Francis, 

Publishers. 2003. 

Nation, J.R., Cardon, A.L., Heard, H.M., Valles, R., and Bratton, G.R. Perinatal Lead Exposure and Relapse to 

Drug-Seeking Behaviour in the Rat: A Cocaine Reinstatement Study. Psychopharmacology. 168:236- 

243, 2003. 

Valles, R., Cardon, A.L., Heard, H.M., Bratton, G.R., and Nation, J.R. Morphine Conditioned Place Preference 

is Attenuated by Perinatal Lead Exposure. Pharm., Biochem. & Behavior. 75:295-300, 2003. 

Nation, J.R., Smith, K.R., and Bratton, G.R. Early Developmental Lead Exposure Increases Sensitivity to 

Cocaine in a Self-Administration Paradigm. Pharm., Biochem. & Behavior. 77(1):127-135, 2004. 

Dearth, R.K., Hiney, J.K. Srivastava, V., Dees, W.L., and Bratton, G.R. Low Level (Pb) Exposure During 

Gestation and Lactation: Assessment of Effects on Pubertal Development in Fisher 344 and Sprague- 

Dawley Female Rats. Life Sciences. 74:1139-1148, 2004. 

Srivastava, V., Dearth, R.K., Hiney, J.K., Ramirez, L.M., Bratton, G.R., and Dees, W.L. The Effects of Low 

Level Lead (Pb) on Steroidogenic Acute Regulatory Protein (STAR) in the Prepubertal Rat Ovary. 

Toxicological Sciences. 77:35-40, 2004. 

Cardon, A.L., Rocha, A., Valles, R., Bratton, G.R., and Nation, J.R. Exposure to Cadmium During Gestation 

and Lactation Decreases Cocaine Self-Administration in Rats. Neurotoxicology. 25:869-875 2004. 

Dehn, L.A., Sheffield, G.G., Follmann, E.H., Duffy, L.K., Thomas, D.L., Bratton, G.R., Taylor, R.J., and O’Hara, 

T.M. Trace Elements in Tissues of Phocid Seals Harvested in the Alaskan and Canadian Arctic- 

Influence of Age and Feeding Ecology. Canadian Journal of Zoology. 83:726-746, 2005. 

Valles, R., Rocha, A., Cardon, A.L., Bratton, G.R., and Nation, J.R. The Effects of the GABA A Antagonist 

Bicuculline on Cocaine Self-Administration in Rats Exposed to Lead During Gestation/Lactation. 

Pharmacology, Biochemistry, and Behavior. 80:611-619, 2005.. 

O’Hara, T., Hoekstra, P., Rosa, C., Dehn, L., Muir, D., Woshner, V., Wise, S., Krahn, M., Reynolds, J., and 

Bratton, G.R. Bowhead Whale Contaminants: A Review of Current Knowledge and Possible Future 

Directions. Submitted Proceedings International Whaling Commission. In press, 2005. 

Rocha, A., Valles, R., Cardon, A.L., Bratton, G.R., and Nation, J.R. Enhanced Acquisition of Cocaine Self- 

Administration in Rats Developmentally Exposed to Lead. Neuropsychopharmacology. 30:2058-2064, 

2005. 

Rocha, A., Valles, R., Bratton, G.R., and Nation, J.R. Diminished Acquisition of Heroin Self-Administration in 

Rats Developmentally Exposed to Lead. Neuropsychopharmacology. , 2005. 

Woshner, V.M., Rosa, C., Bratton, G., Dehn, L., Dau, J., Blake, J., and O’Hara, T.M. Necropsy Findings and 

Mineral Status Associated with a Caribou Mortality Event in the Western Arctic Herd of Alaska, 1999- 

2000. Marine Pollution Bulletin. In press, 2005. 

Dehn, L.A., Follmann, E.H., Rosa, G., Duffy, L.K., Thomas, D.L., Bratton, G.R., Taylor, R.J., and O’Hara, T.M. 

Stable Isotope and Trace Element Status of Subsistence Hunted Bowhead (Balana Mysticefus) and 

Beluga Whales (Delphinapterus Leucas) in Alaska and Gray Whales (Eschrichtius Robustus) in 

Chukotka. Marine Pollution Bulletin. 52:301-319, 2006. 

O’Hara TM, Hanns C, Bratton G. Taylor R, Woshner VM. Essential and non-essential elements in eight tissue 

types from subsistence-hunted bowhead whale: nutritional and toxicological assessment. Int J 

Circumpolar Health 65:228-242, 2006. 

Pine, M.D., Hiney, J.K., Dearth, R.K., Bratton, G.R., and Dees, W.L. IGF-1 Administration to Prepubertal 

Female Rats Can Overcome Delayed Puberty Caused by Maternal Pb Exposure. Reproductive 

Toxicology. 21(1):104-109, 2006.




NAME 

Busbee, David L. 



Professor of Genetics and Toxicology 



DEGREE 


YEAR(s) 


Wichita State University, Wichita, KS BS 1965 Biology 

Wichita State University, Wichita, KS MS 1968 Microbiology 

The University of Texas, Austin, TX PhD 1971 Genetics/Biochemistry 

30. Positions and Honors 


1971-1972 NCI postdoctoral fellow, MD Anderson Hospital and Tumor Institute, The University of Texas 

System Cancer center 

1972-1975 Assistant Professor, Associate Professor, Biology, University of North Texas 

1975-1983 Professor, Biology, University of North Texas 

1972-1983 Director, Genetics Center, University of North Texas 

1983-present Professor of Genetics, College of Veterinary Medicine, Texas A&M University 

1989-1991 Interim Associate Dean for Research and Graduate Programs, College of Veterinary 

Medicine, Texas A&M University 

1997-2000 Acting Associate Dean for Graduate Programs, College of Veterinary Medicine, 


1998-present Professor of Toxicology, School of Rural Public Health, Texas A&M University System 

Health Science Center 


Society of Toxicology, American Aging Association, Society for Marine Mammal Science, American Society 

for Cell Biology and Biochemistry 

Honors 

Golden Key National Honor Society; Beta Beta Beta Outstanding Professor; Mortar Board Outstanding 

Educator; 1987 Beecham Award For Research Excellence; 1987-99 Board of Directors, American Aging 

Association; 1989 TAMU Distinguished Achievement Award for Research; 1992 President, American Aging 

Association; 1995 Carrington Award for Research Excellence; 1995 Fisher Foundation for Medical Research- 

Edwards Award for Research Excellence; George W. Bush, State of Texas Commendation for Research 

Excellence, 1996; TAMU Distinguished Achievement Award for Teaching, 1998. 

B. Selected peer-reviewed publications (selected from 127 total). 

1. Finklea, B., Miller, G. and Busbee, D. Polychlorinated biphenyl residues in blubber of Atlantic bottlenose 

dolphins (Tursiop truncatus) that stranded and died at Matagorda Bay. Bull. Environ. Contam. Toxicol. 

64(3):323-332, 2000. 

2. Srivastava, V.K., Miller, S.D., Crouch, E.A., Schroeder, M., and Busbee, D.L. Activity of DNA polymerase 

in aging human fibroblasts. Biogerontology, 1: 201-216, 2000. 

3. Bielec, P., Gallagher, D., Yang, Y-P, Womack, J., Davis, S., Taylor, J., and Busbee, D. Assignment of 

crystallin-polypeptide 1 (CRYB1) to dolphin chromosome band 16p11 by in situ hybridization. 

Cytogenetics and Cell Genetics 89:96-97, 2000.

4. Miller, S., Han, F., Prado, J. and Busbee, D. Estradiol receptors in dolphin kidney endothelial cells: 

Detection and comparison with estrogen receptors from MCF-7 cells. In Vitro & Molecular Toxicology 

13(3):199-211, 2000. 

5. Miller, S., Kennedy, D., Thomson, J., Han, F., Smith, R., Ing, N., Piedrahita, J., and Busbee, D. A rapid 

and sensitive reporter gene system using green fluorescent protein expression to detect chemicals with 

estrogenic activity. Toxicol. Sci. 55:69-77, 2000. 

6. Bielec, P. Gallagher, D., Womack, J. and Busbee, D. A Comparative Molecular Cytogenetic 

Characterization of the Atlantic Bottlenose Dolphin, Tursiops truncatus. In, Cell and Molecular Biology of 

Marine Mammals. C. Pfeiffer, ed. Krieger Publishing Co., Inc., 2001. 

7. Carvan, M., Miller, S. and Busbee, D. Cellular and molecular investigations utilizing a bottlenose dolphin 

epithelial cell line. In, Cell and Molecular Biology of Marine Mammals. C. Pfeiffer, ed. Krieger Publishing 

Co., Inc., 2001. 

8. Carvan, M. and Busbee, D. Mechanisms of aromatic hydrocarbon toxicity: Implications for dolphin 

morbidity and mortality. In, Monograph-Target Organ Toxicology in Marine Mammals. T. O’Shea, ed. 

Taylor and Francis Publishers, 2002. 

9. Srivastava, V.K. and Busbee, D.L. Replicative enzymes and ageing: Importance of DNA polymerase alpha 

function to the events of cellular ageing. Ageing Res Reviews 29:1-21, 2002. 

10. Srivastava, V. and Busbee, D. Replicative enzymes, DNA polymerase alpha (pol α), and in vitro ageing. 

Experimental Gerontology 19:121-1212, 2003 

11. Pine, M., Schroeder, M., Greer, K., Hokanson, R. and Busbee, D. Generation and Partial characterization 

of a transformed cetacean cell line. J Aquat Toxicol 67(2):195-202, 2004. 

12. Hokanson, R., Miller, S., Hennessey, M., Flesher, M., Hanneman, W., and Busbee, D. Disruption of 

estrogen-regulated gene expression by dioxin: Down-regulation of a gene associated with the onset of 

non-insulin-dependent-diabetes mellitus, type 2 diabetes. Human and Experimental Toxicology 23:555- 

564, 2004. 

13. Srivastava, V. And Busbee, D. Replicative enzymes, DNA polymerase alpha (pol α), and in vitro ageing. 

Experimental Gerontology 19:121-1212, 2004. 

14. Mankame, T.P., Hokanson, R., Chowdhary, R., and Busbee, D.L. Alteration in gene expression in MCF-7 

cells after treatment with the fungicide fenbuconazole (Enable). Toxicology and Industrial Health 20:1-14, 

2004. 

15. Greer, K., Pine, M., and Busbee, D. A Cellular Model of Oxidative Stress Utilizing Green Fluorescent 

Protein to Initiate Reactive oxygen Species. J Amer Aging Assot 27:1-9, 2005. 

16. Mankame, T.P., Hokanson, R., Fudge R, Chowdhary, R., and Busbee, D.L. Altered gene expression in 

human cells treated with the insecticide diazinon: correlation with decreased DNA excision repair 

capacity. Human and Experimental Toxicology, 25:57-65, 2006. 

17. Mankame T., Hokanson R, Fudge R, Chowdhary R, Busbee D. Alteration of gene expression in human 

cells treated with the agricultural chemical diazinon: possible interaction in fetal development. Hum 

Exp Toxicol 25:225-233, 2006.




NAME 

Calvin, James A. 



Executive Associate Vice President for Research 

Professor, Statistics 




DEGREE 


YEAR(s) 


University of Oregon, Eugene, OR B.S. 1976 Computer Science & Mathematics 

Colorado State University, Fort Collins, CO M.S. 1980 Statistics 

Colorado State University, Fort Collins, CO Ph.D. 1985 Statistics 


1989-1990 Visiting Assistant Professor, Department of Statistics, Texas A&M University 

1985-1991 Assistant Professor, Department of Statistics and Actuarial Science, University of Iowa with 

secondary appointment in Division of Biostatistics (1988-1991) 

1991-1993 Assistant Professor, Department of Statistics, Texas A&M University, with secondary 

appointment in Veterinary Anatomy & Public Health Record 

1993-1997 Associate Professor, Department of Statistics, Texas A&M University with secondary 

appointment in Veterinary Anatomy & Public Health Record 

1998 Associate Professor and Head, Department of Statistics, Texas A&M University with 

secondary appointment in Veterinary Anatomy & Public Health 

1998-2004 Professor and Head, Department of Statistics, Texas A&M University with secondary 

appointments in Epidemiology & Biostatistics and Toxicology 

2001-2003 Associate Vice President for Research, Texas A&M University 

2004-present Professor, Department of Statistics, Texas A&M University with secondary appointments in 

Epidemiology & Biostatistics and Toxicology 

2004-present Executive Associate Vice President for Research, Texas A&M University 


1985- Referee for: National Science Foundation, National Institute of Environmental Health Sciences; 

Numerous journals, including JASA, Annals of Statistics, Technometrics, Communications in 

Statistics, JSPI, Journal of Multivariate Analysis, Statistics & Probability Letters, Chemometrics 

and Intelligent Laboratory Systems, Statistics, IIE Transactions 

1986-1988 Iowa Chapter of ASA; Secretary/Treasurer, 1986-1987; President, 1987-1988 

1988-1989 Program Chair, Statistical Education, 1989 JSM, Washington, DC 

1988-1990 ASA Advisory Committee on Continuing Education 

1992-1994 Council of Chapters Representative, Southeast Texas Chapter of ASA 

1992-2001 Associate Editor, Communications in Statistics 

1993-1998 ASA Committee on Membership; Chair of Individual Membership Subcommittee, 1995-1996; 

Chair of Committee on Membership, 1997-1998 

1996 Organizing Editor, Special Issue in Honor of Robert V. Hogg, Central Regional Meeting of 

IMS/ASA, Communications in Statistics, (415 pages) 

1996–1999 Associate Editor, Journal of the American Statistical Association 

1997 ASA Strategic Planning – Meetings and Member Support Task Force 

1997-2000 Executive Editor, Biometrics 

1999-2002 Editorial Board Member, ASA-SIAM Series on Statistics and Applied Probability 

2001 Program Committee, Inaugural Graybill Conference on Linear Models and its Applications 

2001 Program Committee, Board of Mathematical Sciences Chairs’ Colloquium 

2002 Chair, Academic Heads Meeting, Joint Statistical Meetings 

2002-2006 National Institute of Environmental Health Sciences EHS Review Committee

2003-2004 ASA Wilks Memorial Award Committee 

2003-2007 National Research Council NIST Information Technology Assessment Panel 

Professional Affiliations 

Member American Statistical Association; International Statistical Institute; Institute of Mathematical 

Statistics; International Biometric Society 

Awards and Honors 

James L. Madison Award, Colorado State University 

Mu Sigma Rho (Statistics Honor Society) 

JASA–Applications and Case Studies Invited Paper, 2001 Joint Statistical Meeting 

Don Owen Award, American Statistical Association 

Elected Member, International Statistical Institute 

Fellow, American Statistical Association 


1. Bennett, G. D., An, J., Craig, J. C., Gefrides, L. A., Calvin, J., A. and Finnell, R. H. (1998) Neurulation 

abnormalities secondary to altered gene expression in neural tube defect susceptible Splotch embryos, 

Teratology, 57, 17-29. 

2. Calvin, J.A. (1998) A review of Regression Models for Categorical and Limited Dependent Variables, by J. 

Scott Long, Technometrics, 40, 80. 

3. Thompson, J. A., Brimacombe, M., Calvin, J. A., Tomaszewski, M. A., Davidson, T. J. and Magee, D. D. 

(1998) Effects of environmental management on seasonal decrease in milk production in Holsteins, Journal 

of the American Veterinary Medical Association. 

4. Edwards, J. C., Maldonado, F. G. and Calvin, J. A. (1999) The effects of differently weighting interview 

scores on the admission of underrepresented minority medical students, Academic Medicine, 74, 59-61. 

5. Bennett, G. D., Wlodarczyk, B., Calvin, J. A., Craig, J. C. and Finnell, R. H. (2000) Valproic acid-induced 

alterations in growth and neurotrophic factor, Reproductive Toxicology, 14, 1-11. 

6. Nedumaran, G., Pignatiello, J. J., Jr. and Calvin, J. A. (2000). Estimating the time of a step-change with 

chi2 control charts, Quality Engineering, 13, 153-159. 

7. McDougal, A., Wormke, M., Calvin, J., and Safe, S. (2001) Tamoxifen-induced 

antitumorigenic/antiestrogenic action synergized by a selective Aryl hydrocarbon receptor modulator, 

Cancer Research, 61, 3902-3907. 

8. Reese, C. S., Calvin, J. A., George, J. C., Tarpley, R. J. (2001) Estimation of fetal growth and gestation in 

Bowhead whales, Journal of the American Statistical Association, 96, 915-938 (with discussion). 

9. Shalat, S. L., Donnelly, K. C., Freeman, N. C. G., Calvin, J. A., Ramesh, S., Jimenez, M., Black, K., 

Coutinho, C., Needham, L. L., Barr, D. B. and Ramirez, J. (2003) Nondietary ingestation of pesticides by 

children in an agricultural community on the US/Mexico border: preliminary results, Journal of Exposure 

Analysis and Environmental Epidemiology, 13(1), 42-50. 

10. Guan, Y., Sherman, M. and Calvin, J. A. (2004) A nonparametric test for spatial isotropy using 

subsampling, Journal of the American Statistical Association, 99, 810-821. 

11. Carrillo-Zuniga, G., Coutinho, C., Shalat, S. L., Freeman, N. C. G., Black, K., Jimenez, W., Calvin, J., 

Ramirez, J., Marchenko, Y., Cizmas, L. and Donnelly, K. C. (2004) Potential sources of childhood exposure 

to pesticides in an agricultural community, Journal of Children's Health. 

12. Donnelly, K., Huebner, H., Claxton, L., Calvin, J., Vos, G., Cizmas, L. and He, L. (2005) Biodegradation of 

simple chemical mixtures in soil, Environmental Toxicology and Chemistry, 24:2839-45. 

13. Guan, Y., Sherman, M. and Calvin, J. A. (2006) On asymptotic properties of the mark variogram estimator 

of a marked point process, Journal of Statistical Planning and Inference – to appear. 

14. Guan, Y., Sherman, M. and Calvin, J. A. (2006) Assessing isotropy for spatial point processes, Biometrics, 

62:119-125.




NAME 

Carroll, Raymond J. 


Rjcarroll 


Distinguished Professor 



DEGREE 


YEAR(s) 

University of Texas at Austin B.A. 1971 Mathematics 

Purdue University, West Lafayette Ph.D. 1974 Statistics 


EXPERIENCE: 

07/87 – Present: Distinguished Professor of Statistics, Nutrition and Toxicology, Texas A&M University. 

07/98 – 12/99: Fairhill Professor of Biostatistics, University of Pennsylvania School of Medicine. 

07/74 – 08/87: Assistant, Associate and Full Professor, University of North Carolina. 

07/90 – Present: Guest Researcher, National Cancer Institute. 

SELECTED HONORS: 

MERIT Award, National Cancer Institute, 2005 

Sacks Award, National Institute of Statistical Sciences, 2003. 

Mitchell Prize, International Society for Bayesian Analysis, 2003. 

Fisher Lecture, COPSS (Committee of Presidents of Statistical Societies), 2002 

Snedecor Award from COPSS, 1997. 

Alexander von Humboldt Senior Research Award, 1996. 

COPSS Presidents’ Award (IMS, ASA, ENAR, WNAR, CSS), 1988. 

Wilcoxon Prize, American Society of Quality Control, 1986. 

Fellow, ASA (1982), Fellow IMS (1984), Elected Member ISI (1991). 

SELECTED EDITORIAL RESPONSIBILITIES: 

Editor, Biometrics, 1998-2001. 

Editor, Journal of the American Statistical Association, Theory and Methods, 1988-1990. 

BOOKS: 

Carroll, R.J. & Ruppert, D. (1988). Transformation and Weighting in Regression. Chapman and Hall. 

Carroll, R.J., Ruppert, D. & Stefanski, L.A. (1995). Measurement Error in Nonlinear Models. Chapman & Hall. 

Ruppert, D., Wand, M. P. & Carroll, R. J. (2003). Semiparametric Regression. Cambridge University Press. 

Carroll, R.J., Ruppert, D., Stefanski, L.A. & Crainiceanu, C. M. (2006). Measurement Error in Nonlinear Models, 

Second edition. CRC Press - Chapman & Hall. 

SELECTED PUBLICATIONS (from 278): 

Carroll, R.J., Ruppert, D. & Welsh, A. (1998). Local estimating equations. Journal of the American Statistical 

Association, 93, 214-227. 

Carroll, R.J., Maca, J.D. & Ruppert, D. (1999). Nonparametric regression with errors in corvariates. Biometrika, 

84, 881-897. 

Kipnis, V., Midthune, D., Freedman, L.S., Bingham, S., Schatzkin, A. & Carroll, R.J. (2001). Empirical evidence 

of correlated biases in dietary instruments and its implication. American Journal of Epidemiology, 153, 394- 

403. 

Carroll, R.J., Härdle, W. & Mammen, E. (2002). Estimations in an additive model when components are linked 

parametrically. Journal of Econometrics, 18, 886-912. 

Morris, J. S., Wang, N., Lupton, J. R., Chapkin, R. S., Turner, N. D. Hong, M. Y. & Carroll, R. J. (2002). A

Bayesian analysis of colonic crypt structure and coordinated response incorporating missing crypts. 

Biostatistics, 3, 529-546. 

Rathouz, P. J., Satten, G. A. & Carroll, R. J. (2002). Semiparametric inference in matched case—control studies 

with missing covariate data. Biometrika, 89, 905-916. 

Morris, J. S., Vannucci, M., Brown, P. J. & Carroll, R. J. (2003). Wavelet-based nonparametric modeling of 

hierarchical functions in colon carcinogenesis. Journal of the American Statistical Association (Editor's 

Invited Paper for 2003), 98, 573-597. 

Carroll, R. J. (2003). Variances are not always nuisance parameters: The 2002 R. A. Fisher Lecture. 

Biometrics, 59, 211-220. 

Carroll, R. J. & Hall, P. (2004). Low-order approximations in deconvolution and regression with errors in 

variables. Journal of the Royal Statistical Society, Series B, 66, 31-46. 

Xiao, Z., Linton, O. B., Carroll, R. J. & Mammen, E. (2004). More efficient kernel estimation in nonparametric 

regression with autocorrelated errors. Journal of the American Statistical Association, 98, 980-992. 

Hu, Z., Wang, N. & Carroll, R. J. (2004). Profile-kernel versus backfitting in the partially linear model for 

longitudinal/clustered data. Biometrika, 91, 251-262. 

Liang, H., Wang, S., Robins, J. & Carroll, R. J. (2004). Estimation in partially linear models with missing 

covariates. Journal of the American Statistical Association, 99, 357-367. 

Carroll, R.J., Ruppert, D., Tosteson, T. D., Crainiceanu, C. & Karagas, M. R. (2004). Nonparametric regression 

and instrumental variables. Journal of the American Statistical Association, 99, 736-750. 

Wang, N., Carroll, R. J. & Lin, X. (2005). Efficient semiparametric marginal estimation for longitudinal/clustered 

data. Journal of the American Statistical Association, 100, 147-157. 

Chatterjee, N., Kalaylioglu, Z. \& Carroll, R. J. (2005). A new paradigm of conditional-likelihoods for exploiting 

gene-environment independence in family based case-control studies. Genetic Epidemiology, 28, 138-156. 

Chatterjee, N. & Carroll, R. J. (2005). Semiparametric maximum likelihood estimation in case-control studies of 

gene-environment interactions. Biometrika, 92, 399-418. 

Spinka, C., Carroll, R. J. & Chatterjee, N. (2005). Analysis of case-control studies of genetic and environmental 

factors with missing genetic information and haplotype phase ambiguity. Genetic Epidemiology, 29,108- 

127. 

Carroll, R.J., Midthune, D., Freedman, L.S. & Kipnis, V. (2006) Seemingly unrelated measurement error 

models, with application to nutritional epidemiology. Biometrics 62, 75-84 

Lin, X., & Carroll, R.J. (2006) Semiparametric estimation in general repeated measures problems. Journal of the 

Royal Statistical Society, Series B, 68, 68-88 

Morris J.S., & Carroll, R.. (2006). Wavelet-based functional mixed models. Journal of the Royal Statistical 

Society, Series B, 68, 179-199 

Sun, N., Carroll, R.J. & Zhao, H. (2006) Bayesian error analysis model (BEAM) for reconstructing transcriptional 

regulatory networks. Proc. of the National Academy of Sciences, 103, 7988-7993 

Lyon, J.L., Alder, S.C., Stone, M.B., School, A., Reading, J.C., Holubkov, R., Shen, X., White, G.L., Hegmann, 

K.T., Anspaugh, L., Hoffman, F,O., Simon, S.L., Thomas, B., Carroll, R.J., Meikle, A.W. (2006). Thyroid 

disease associated with exposure to the Nevada Test Site radiation: a re-evaluation based on corrected 

dosimety and examination data. Epidemiology, 17:604-614. 

Ma, Y., & Carroll, R.J. (2007). Locally efficient estimators for semiparametric models with measurement error. 

Journal of the American Statistical Association, to appear. 

Liang, H., Wang, S. & Carroll, R.J. (2006) Partially linear models with missing response variables and errorprone 

covariates. Biometrika, to appear. 

Liang, F., Liu, C. & Carroll, R.J. (2007). Stochastic approximation in Monte Carlo computation. Journal of the 

American Statistical Association, to appear.




NAME 



RChapkin 


Professor and University Faculty Fellow 



DEGREE 


YEAR(s) 


University of Guelph, Ontario, Canada B.Sc. 1981 Nutrition & Biochemistry 

University of Guelph, Ontario, Canada M.Sc. 1983 Nutrition 

University of California - Davis Ph.D. 1986 Nutr. & Physiol. Chemistry 

University of California - Davis Post-doc 1986-88 Cell Biology 



1986-1988: Postdoctoral Fellow, Immunology-Tumor Biology Laboratory, Department of Cell Biology and Human 

Anatomy, School of Medicine, University of California-Davis. 

1988-1993: Assistant Professor, Human Nutrition, Center for Environmental and Rural Health, Texas A&M 

University. 

1992: Pew National Nutrition Program Scholar. 

1994-1999: Associate Professor, Department of Veterinary Integrated Biosciences and Faculty of Nutrition. 

1999-Present: Professor, Nutrition, Center for Environmental and Rural Health (CERH), Texas A&M University. 

2001-Present: University Faculty Fellow, Texas A&M University. 

2002-2005: Chair, Intercollegiate Faculty of Nutrition, Texas A&M University 

2004-Present: Member, Division of Hematology/Oncology, Scott & White Hospital, Texas A&M Health Science 

Center. Director, Genomics and Bioinformatics Facility Core, CERH, Texas A&M University. 

Honors and National Review Panels 

1991-1992: Pew National Nutrition Program Faculty Scholar. 

1996: American Society for Nutritional Sciences Bio Serv Award in Experimental Animal Nutrition. 

1999-Present: American Institute for Cancer Research Grant Review Panel 

2000: Texas A&M Agricultural Experiment Station Faculty Fellow 

1999-2000: Chair, Diet-Cancer Research Interest Section, American Society for Nutritional Sciences. 

2000-2001: NIH Temporary Panel Member: Metabolic Pathology Study Section 

2001-2006: Texas A&M University Faculty Fellow 

2002-2004: Editorial Board, Journal of Nutrition 

2002-2005: NIH Charter Member: Metabolic Pathology/Chemo-Dietary prevention (CDP) Study Sections 

2005-2007: Editorial Board, Chemistry and Physics of Lipids 

2006: Sigma Xi Distinguished Scientist Award, Texas A&M University Chapter 

2007: Texas A&M Senior Faculty Fellow 

B. Selected peer-reviewed publications from a total of 150. 

N.R. Murray, C. Weems, L. Chen, J. Leon, W. Yu, L.A. Davidson, L. Jamieson, R.S. Chapkin, A. Thompson, A.P. 

Fields. Protein kinase CβII and TGFβRII in ω-3 fatty acid-mediated inhibition of colon carcinogenesis. Journal of 

Cell Biology 157:915-920, 2002. 

M.Y. Hong, R.S. Chapkin, R. Barhoumi, R.C. Burghardt, N.D. Turner, C.E. Henderson, L.M. Sanders, Y.Y. Fan, L.A. 

Davidson, M. Murphy, R.J. Carroll and J.R. Lupton. Fish oil feeding increases the unsaturation index in 

mitochondrial phospholipids, enhancing reactive oxygen species generation and initiating apoptosis in rat 

colonocytes. Carcinogenesis 23:1831-1834, 2002. 

L.A. Davidson, J.R. Lupton, E. Miskovsky, A.P. Fields and R.S. Chapkin. Quantification of human intestinal gene 

expression profiles using exfoliated colonocytes: A pilot study. Biomarkers 8:51-61, 2003.

L.K. Bancroft, J.R. Lupton, L.A. Davidson, M.E. Murphy, R.J. Carroll and R.S. Chapkin. Dietary fish oil reduces 

oxidative DNA damage in rat colonocytes. Free Radical Biology & Medicine 135:149-159, 2003. 

Y.Y. Fan, T.E. Spencer, N. Wang, M.P. Moyer and R.S. Chapkin. Chemopreventive n-3 fatty acids activate RXRα 

in colonocytes. Carcinogenesis 24:1-8, 2003. 

D.W.L. Ma, J. Seo, L.A. Davidson, E.S. Callaway, Y.Y. Fan, J.R. Lupton and R.S. Chapkin. n-3 PUFA alter 

caveolae lipid composition and resident protein localization in mouse colon. Faseb Journal, April 2004, 

10.1096/fj.03-0604fje, 18:1040-1042, 2004. 

L.M. Sanders, C.E. Henderson, M.Y. Hong, R. Barhoumi, R.C. Burghardt, R.J. Carroll, N.D. Turner, R.S. Chapkin 

and J.R. Lupton. Pro-oxidant environment of the colon compared to the small intestine may contribute to 

greater cancer susceptibility. Cancer Letters 208:155-161, 2004. 

K.C. Switzer, Y-Y. Fan, N. Wang, D.M. McMurray and R.S. Chapkin. Dietary n-3 polyunsaturated fatty acids 

promote activation-induced cell death in Th1-polarized murine CD4 + T-cells. Journal of Lipid Research, 

45:1482-1492, 2004. 

L.A. Davidson, D.V. Nyuyen, R.M. Hokanson, E.S. Callaway, R.B. Isett, N.D. Turner, E.R. Dougherty, J.R. Lupton, 

R.J. Carroll and R.S. Chapkin. Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures 

during colon cancer initiation and progression in the rat. Cancer Research 64:6797-6804, 2004. 

L.M. Sanders, C.E. Henderson, M.Y. Hong, R. Barhouim, R.C. Burghardt, N. Wang, C.M. Spinka, R.J. Carroll, N.D. 

Turner, R.S. Chapkin and J.R. Lupton. Enhancement of reactive oxygen species by dietary fish oil and 

attenuation of antioxidant defenses by dietary pectin coordinately heightens apoptosis in rat. Journal of Nutrition 

134:3233-3238, 2004. 

K.C. Switzer, D.N. McMurray and Robert S. Chapkin. Effects of dietary n-3 polyunsaturated fatty acids on T cell 

membrane composition and function. Lipids 39: 1163-1170, 2004. 

L.H. Ly, R. Smith, R.S. Chapkin and D.N. McMurray. Dietary n-3 polyunsaturated fatty acids suppress splenic CD4 + 

T-cell function in IL-10 (-/-) mice. Clinical & Experimental Immunology 139: 202-209, 2005. 

D.W.L. Ma, R.H. Finnell, L.A. Davidson, E.S. Callaway, O. Spiegelstein, J.A. Piedrahita, J.M. Salbaum, C. Kappen, 

B. Weeks, J. James, D. Bozinov, J.R. Lupton and R.S. Chapkin. Folate transport gene inactivation in mice 

increases sensitivity to colon carcinogenesis. Cancer Research 65:887-897, 2005. 

G.D. Zhou, N. Popovic, J.R. Lupton, N.D. Turner, R.S. Chapkin and K.C. Donnelly. Tissue-specific attenuation of 

endogenous DNA I-compounds in rats by carcinogen azoxymethane: possible role of fish oil in colon cancer 

prevention. Cancer Epidemiology Biomarkers & Prevention 14:1230-1235, 2005. 

P. Zhang, R. Smith, R.S. Chapkin and D.N. McMurray. Dietary n-3 Polyunsaturated fatty acids modulate the 

Th1/Th2 balance towards the Th2 pole by suppression of Th1 development. Journal of Nutrition 135:1745- 

1751, 2005. 

M.Y. Hong, N.D. Turner, R.J. Carroll, R.S. Chapkin and J.R. Lupton. Differential response to oxidative DNA 

damage may explain aspects of the cancer susceptibility between small and large intestine. Experimental 

Biology and Medicine 230:464-471, 2005. 

M.Y. Hong, L.K. Bancroft, N.D. Turner, L.A. Davidson, M.E. Murphy, R.J. Carroll, R.S. Chapkin and J.R. Lupton. 

Fish oil decreases oxidative DNA damage by enhancing apoptosis in rat colon. Nutrition & Cancer 52:166-175, 

2005. 

L.D. Liu, N. Wang, J.R. Lupton, N.D. Turner, R.S. Chapkin and L.A. Davidson. A two-stage normalization method for 

partially degraded mRNA microarray data. Bioinformatics 21:4000-4006, 2005. 

Y. Ng, R. Barhoumi, R.B. Tjalkens, Y.Y. Fan, S. Kolar, N. Wang, J.R. Lupton and R.S. Chapkin. The role of 

docosahexaenoic acid mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes. 

Carcinogenesis 26:1914-1921, 2005. 

L.H. Ly, R. Smith, K.C. Switzer, R.S. Chapkin, and D.N. McMurray. Dietary eicosapentaenoic acid modulates 

CTLA-4 expression in murine CD4 + T-cells. Prostaglandins, Leuk. Essential Fatty Acids 74:29-37, 2006. 

J. Seo, R. Barhoumi, A.E. Johnson, J.R. Lupton and R.S. Chapkin. Docosahexaenoic acid selectively inhibits 

plasma membrane targeting of lipidated proteins. FASEB Journal 20:770-772, 2006. 

P. Zhang, W. Kim, R., L. Zhou, N. Wang, L.H. Ly, D.N. McMurray and R.S. Chapkin. Dietary fish oil inhibits antigenspecific 

Th1 cell development by suppression of clonal expansion. Journal of Nutrition 136:2391-2398, 2006. 

R.S. Chapkin, L.A. Davidson, L. Ly, B.R. Weeks, J.R. Lupton, and D.N. McMurray. Immunomodulatory effects of 

omega-3 fatty acids: Putative link to inflammation and colon cancer. Journal of Nutrition 137:200S-204S, 2007. 

R.S. Chapkin, D.N. McMurray and J.R. Lupton. Colon cancer, fatty acids and anti-inflammatory compounds. 

Current Opinions in Gastroenterology 23:48-54, 2007

NAME 

W. Les Dees 





WLDees 





DEGREE 


YEAR(s) 


Texas A&M University, College Station, TX BS 1971 Animal Science 

Texas A&M University, College Station, TX BS 1972 Biomedical Science 

Texas A&M University, College Station, TX MS 1979 Phys. of Reproduction 

Texas A&M University, College Station, TX PhD 1982 Veterinary Anatomy 

U. of TX Southwestern Med. Ctr., Dallas, TX Postdoc 1984 Neuroendocrinology 

C. Positions and Honors 

1985 Asst. Instructor, Physiology, Univ. of TX Southwestern Med. Center, Dallas 

1985-1986 Research Asst. Professor, Physiology (Division of Neuropeptides), as above 

1986-1991 Assistant Professor, Veterinary Integrative Biosciences, Texas A&M University 

1989-present Member, Faculty of Toxicology, as above 

1990-present Member, Faculty of Neuroscience, as above 

2000-present Member, Faculty of Reproductive Biology, as above 

1992-1997 Associate Professor, as above 

1998-present Professor, as above 

NIH Research Scientist Development Award, 1987-92 and 1993-98; Carrington Laboratories Research Award, 

1989; Pfizer Research Award, 1996; TAMU Distinguished Achievement in Research, 1996. 

Advisory Committees 

Member, NIH Alcohol and Toxicology III Study Section, 1999-2003; Member, NSF Integrative Biology and 

Neuroscience Subcommittee, 1995-1998; Member, NIH Special Emphasis Panels, 1996, 1997, 1999-2004; 

Member, NIH NIAAA Center Review Subcommittee, 2003; Member, NIH Special Emphasis Panel for R-21 

Grants, 2004. 

D. Selected peer-reviewed publications (Selected from over 80 reviewed publications) 

Dees, WL and CW Skelley. The effects of ethanol during the onset of female puberty. Neuroendocrinology 

51:64-69, 1990. 

Hiney, JK, WL Dees. Ethanol inhibits LHRH release from the median eminence of prepubertal female rats in 

vitro: Investigation of its actions on norepinephrine and prostaglandin-E 2 . Endocrinology, 128:1404- 

1408, 1991. 

Hiney, JK, SR Ojeda, WL Dees. Insulin-like growth factor I (IGF-I): A possible metabolic signal involved in the 

regulation of female puberty. Neuroendocrinology, 54:420-423, 1991. 

Aguila, MC, WL Dees, WE Haensly, SM McCann. Evidence that somatostatin is localized and synthesized in 

lymphoid organs. Proceedings of the Natlonal Academy of Science (USA), 88:11485-11489, 1991. 

Nyberg C, JK Hiney, JB Minks, WL Dees. Ethanol affects NMDA-induced LHRH release and the onset of 

female puberty. Neuroendocrinology 57:863-868, 1993. 

Rettori V, N Belova, WL Dees, CL Nyberg, M Gimeno and SM McCann. Role of nitric oxide in the control of 

LHRH release in vivo and in vitro. Proc. Natl. Acad. Sci. (USA), 90:10130-10134, 1993. 

Berg-von der Emde, K, WL Dees, JK Hiney, GA Dissen, DF Hill, ME Casta, and SR Ojeda. Neurotropins and 

the neuroendocrine brain: Brain-derived neurotrophic factor (BDNF) selectively promotes the survival of 

hypothalamic dopaminergic neurons expressing low-affinity nerve growth factor receptors (NGFR). J. 

Neurosci. 15:4223-4237, 1995.

Nyberg, CL, V Srivastava, JK Hiney, T Lara, and WL Dees. NMDA-receptor synthesis and LH release in 

immature female rats: Effects of stage of pubertal development and exposure to ethanol. Endocrinology 

136:2874-2880, 1995. 

Srivastava, V, JK Hiney, CL Nyberg, and WL Dees. Influence of ethanol on insulin-like growth factor I (IGF-I) 

and IGF-I receptor synthesis during female puberty. Alc. Clin. Exp. Res 19:1467-1473, 1995. 

Dees, WL, JK Hiney, TD Schultea, A Mayerhofer, M Danilchik, GA Dissen, and SR Ojeda. The primate ovary 

contains a population of catecholaminergic neuron-like cells expressing nerve growth factor receptors. 

Endocrinology 136:5760-5768, 1995. 

Hiney, JK, V Srivastava, CL Nyberg, SR Ojeda, and WL Dees. Insulin-like growth factor-I (IGF-I) of peripheral 

origin acts centrally to accelerate the initiation of female puberty. Endocrinology 137:3717-3728, 1996. 

Srivastava, V, JK Hiney, and WL Dees. Effects of ethanol on the intraovarian insulin-like growth factor-1 

system in the prepubertal female rat. Alc. Clin. Exp. Res. 23:293-300, 1999. 

Dees, WL, G Dissen, JK Hiney, F Lara, and SR Ojeda. Alcohol ingestion inhibits increased secretion of 

puberty-related hormones in developing female rhesus monkeys. Endocrinology 141:1325-1331, 2000. 

Mastronardi, CA, WH Yu, VK Srivastava, WL Dees, and SM McCann. Lipposaccharide-induced leptin release 

is neurally controlled. Proc. Natl. Acad. Sci. USA 98:14720-14225, 2001. 

Hiney, JK, S Sower, W Yu, SM McCann, and WL Dees. Neurons in the preoptic hypothalamic region of the 

rat brain contain Lamprey GnRH-111, mammalian LHRH, or both peptides. Proceedings of the National 

Academy of Science (USA) 99:2386-2391, 2002. 

Dearth, RK, JK Hiney, V Srivastava, SB Burdick, GR Bratton, and WL Dees. Effects of lead (Pb) exposure 

during gestation and lactation on female pubertal development. Reproductive Toxicology 16:343-352, 

2002. 

Srivastava, VK, RK Dearth, JK Hiney, V Chandrashekar, JA Mattison, A Bartke, and WL Dees. Alcohol 

suppresses the synthesis of insulin like growth factor-1 in prepubertal transgenic female mice 

overexpressing the bovine growth hormone gene. Alc. Clin. Exp. Res. 26:1697-1702, 2002. 

Hiney, JK, RK Dearth, VK Srivastava, V Rettori, and WL Dees. Actions of alcohol on epidermal growth factorreceptor 

activated luteinizing hormone secretion. J. Studies Alcohol 64:809-816, 2003. 

Dearth, RK, JK Hiney, V Srivastava, WL Dees, and GR Bratton. Low level lead (Pb) exposure during 

gestation and lactation: Assessment of effects on female pubertal development in Fisher 344 and 

Sprague-Dawley rats. Life Sciences 74:1139-1148, 2004. 

Srivastava, VK, RK Dearth, JK Hiney, LM Ramirez, GR Bratton, and WL Dees. The effects of low-level Pb on 

steroidogenic acute regulatory protein (STAR) in the prepubertal rat ovary. Toxicological Sciences 77:35- 

40, 2004. 

Hiney, JK, VK Srivastava, RK Dearth, and WL Dees. Influence of estradiol on IGF-1 induced luteinizing 

hormone secretion. Brain Research 1013:91-97, 2004. 

Dissen, GA, SR Ojeda, RK Dearth, M Scott, and WL Dees. Alcohol alters prepubertal luteinizing hormone 

(LH) secretion in female rhesus monkeys by a hypothalamic action. Endocrinology 145:4558-4564, 

2004. 

Dees, WL, VK Srivastava, and JK Hiney. Alcohol alters insulin-like growth factor-1 activated Oct 2 POU gene 

expression in the immature female hypothalamus. J. Studies Alcohol 66:35-45, 2005. 

Pine, M, RK Dearth, JK Hiney, and WL Dees. Manganese acts centrally to stimulate LH secretion in immature 

female rats. A potential influence on female pubertal development. Toxicological Sciences 85:880-885, 

2005. 

Srivastava VK, E Vijayan, JK Hiney and WL Dees. Effect of ethanol on follicle stimulating hormone induced 

steroidogenic acute regulatory protein in cultured rat granulosa cells. Alcohol 37: 105-111, 2005. 

Pine, MD, K Hiney, RK Dearth, GR Bratton, and WL Dees. IGF-1 administration to prepubertal female rats 

can overcome delayed puberty caused by maternal lead (Pb) exposure. Reproductive Toxicology 

21:104-109, 2006. 

Lee, B, MD Pine, L Johnson, V Rettori, JK Hiney and WL Dees. Manganese acts centrally to activate 

reproductive hormone secretion and pubertal development in male rats. Reprodictive Toxicology 22:580- 

585, 2006. 

Dees, WL, JK Hiney, NH McArthur, GA Johnson, GA Dissen and SR Ojeda. Origin and ontogeny of 

mammalian ovarian neurons. Endocrinology 147: 3789-3796, 2006. 

.




NAME 

Donnelly, Kirby C. 






DEGREE 


YEAR(s) 


Texas A&M University, College Station BS 1974 Microbiology 

Texas A&M University, College Station PhD 1988 Toxicology 

Texas A&M University, College Station Postdoctoral 1989-1991 Environmental Science 



1973-1988 Technician, Technician II, Department of Soil and Crop Sciences, Texas A&M University, 

College Station, TX (TAMU) 

1984-1988 Graduate Research Associate, Department of Veterinary Physiology and Pharmacology, 

TAMU 

1989-1991 Postdoctoral Research Associate, Department of Soil and Crop Sciences, TAMU 

1990-1991 Lecturer, Department of Soil and Crop Sciences, TAMU 

1991-1997 Assistant Professor, Department of Veterinary Anatomy and Public Health, TAMU 

1997-2002 Associate Professor, Department of Veterinary Anatomy and Public Health, TAMU 

1999-2002 Interim Head, Department of Environmental & Occupational Health, School of Rural Public 

Health, Texas A&M University Health Science Center 

2002-present Professor and Head, Department of Environmental & Occupational Health, School of Rural 

Public Health, Texas A&M University Health Science Center 


Executive Committee, School of Rural Public Health, Texas A&M University System Health Science Center 

Faculty Advisory Committee, College of Veterinary Medicine, Texas A&M University 

Service as ad hoc reviewer: Environmental Toxicology & Chemistry (Editorial Board 2001-2003); Waste 

Management & Research; USEPA-NCERQA; Environmental Science & Technology; Bioremediation; 

Journal of Toxicology & Environmental Health 

B. Selected peer-reviewed publications (selected from 87 peer-reviewed publications) 

1. Barr DB, Landsittel D, Nishioka M, Thomas K, Curwin B, Raymer J, Donnelly KC, McCauley L, Ryan B: A 

survey of laboratory and statistical issues related to farmworker exposure studies. Environ Health Persp 

2006; 114(6): 961-968 

2. Matson CW, Lambert MM, McDonald TJ, Autenrieth RL, Donnelly KC, Islamzadeh A, Politov DI, Bickham 

JW: Evolutionary Toxicology: Population-Level Effects of Chronic Contaminant Exposure on the Marsh 

Frogs (Rana ridibunda) of Azerbaijan. Environ Health Persp 2006; 114(4); 547-552 

3. Cho TM, Wild JR, Donnelly KC, Tiffany-Castiglioni E: Degradation of Organophosphorous Neurotoxicity in 

SY5Y Neuroblastoma Cells by Organophosphorus Hydrolase (OPH). J Tox Environ Health 2006; 69:1413- 

1429. 

4. Zhou GD, Popovic N, Lupton JR, Turner ND, Chapkin RS, Donnelly KC: Tissue-specific attenuation of 

endogenous DNA I-compounds in rats by carcinogen azoxymethane: possible role of dietary fish oil in 

colon cancer prevention. Cancer Epidemiol Biomarkers Prev 2005; 14(5):1230-5 

5. Matson CW, Palatnikov GM, McDonald TJ, Autenrieth RL, Donnelly KC, Anderson TA, Canas JE, 

Islamzadeh A, Bickham JW: Patterns of genotoxicity and contaminant exposure: evidence of genomic

instability in the marsh frogs (Rana ridibunda) of Sumgayit, Azerbaijan. Environ Toxicol Chem 2005; 

24(8):2055-64 

6. Matson CW, Palatnikov G, Islamzadeh A, McDonald TJ, Autenrieth RL, Donnelly KC, Bickham JW: 

Chromosomal damage in two species of aquatic turtles (Emys orbicularis and Mauremys caspica) 

inhabiting contaminated sites in Azerbaijan. Ecotoxicology 2005; 14(5):513-25 

7. Donnelly KC, Huebner HJ, Claxton LD, Calvin JA, Vos GA, Cizmas L, He LY: Biodegradation of simple 

chemical mixtures in soil. Environ Toxicol Chem 2005; 24(11):2839-45 

8. Black K, Shalat SL, Freeman NC, Jimenez M, Donnelly KC, Calvin JA: Children's mouthing and foodhandling 

behavior in an agricultural community on the US/Mexico border. J Expo Anal Environ Epidemiol 

2005; 15(3):244-51 

9. Zhou GD, Randerath K, Donnelly KC, Jaiswal AK: Effects of NQO1 deficiency on levels of cyclopurines 

and other oxidative DNA lesions in liver and kidney of young mice. Int J Cancer 2004; 112(5):877-83 

10. Reeves WR, McDonald TJ, Cizmas L, Donnelly KC: Partitioning and desorption behavior of polycyclic 

aromatic hydrocarbons from disparate sources. Sci Total Environ 2004; 332(1-3):183-92 

11. Freeman NC, Shalat SL, Black K, Jimenez M, Donnelly KC, Calvin A, Ramirez J: Seasonal pesticide use in 

a rural community on the US/Mexico border. J Expo Anal Environ Epidemiol 2004; 14(6):473-8 

12. Falahatpisheh M, Kerzee J, Metz R, Donnelly K, Ramos K: Inducible cytochrome P450 activities in renal 

glomerular mesangial cells: biochemical basis for antagonistic interactions among nephrocarcinogenic 

polycyclic aromatic hydrocarbons. J Carcinog 2004; 3(1):12 

13. Donnelly K, Lingenfelter RA, Cizmas L, Falahatpisheh M, Qian Y, Tang Y, Garcia S, Ramos K, Tiffany- 

Castiglioni E, Mumtaz M: Toxicity Assessment of Complex Mixtures Remains a Goal. Environ Tox and 

Pharm 2004; 18:135-141 

14. Cizmas L, Zhou GD, Safe SH, McDonald TJ, Zhu L, Donnelly KC: Comparative in vitro and in vivo 

genotoxicities of 7H-benzo[c]fluorene, manufactured gas plant residue (MGP), and MGP fractions. Environ 

Mol Mutagen 2004; 43(3):159-68 

15. Cizmas L, McDonald TJ, Phillips TD, Gillespie AM, Lingenfelter RA, Kubena LF, Phillips TD, Donnelly KC: 

Toxicity characterization of complex mixtures using biological and chemical analysis in preparation for 

assessment of mixture similarity. Environ Sci Technol 2004; 38(19):5127-33 

16. Carrillo-Zuniga G, Coutinho C, Shalat SL, Freeman NCG, Black K, Jimenez W, Calvin J, Ramirez J, 

Marchenko Y, Cizmas L, Donnelly K: Potential Sources of Childhood Exposure to Pesticides in an 

Agricultural Community. Journal of Children's Health 2004; 2(1):1-11 

17. Tang Y, Donnelly KC, Tiffany-Castiglioni E, Mumtaz MM: Neurotoxicity of polycyclic aromatic hydrocarbons 

and simple chemical mixtures. J Toxicol Environ Health A 2003; 66(10):919-40 

18. Swartz CD, Donnelly KC, Islamzadeh A, Rowe GT, Rogers WJ, Palatnikov GM, Mekhtiev AA, Kasimov R, 

McDonald TJ, Wickliffe JK, Presley BJ, Bickham JW: Chemical contaminants and their effects in fish and 

wildlife from the industrial zone of Sumgayit, Republic of Azerbaijan. Ecotoxicology 2003; 12(6):509-21 

19. Shalat SL, Donnelly KC, Freeman NC, Calvin JA, Ramesh S, Jimenez M, Black K, Coutinho C, Needham 

LL, Barr DB, Ramirez J: Nondietary ingestion of pesticides by children in an agricultural community on the 

US/Mexico border: preliminary results. J Expo Anal Environ Epidemiol 2003; 13(1):42-50 

20. Mueller DC, Bonner JS, McDonald SJ, Autenrieth RL, Donnelly KC, Lee K, Doe K, Anderson J: The use of 

toxicity bioassays to monitor the recovery of oiled wetland sediments. Environ Toxicol Chem 2003; 

22(9):1945-55 

21. Hong MS, Hong SJ, Barhoumi R, Burghardt RC, Donnelly KC, Wild JR, Venkatraj V, Tiffany-Castiglioni E: 

Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus 

compounds. Toxicol Appl Pharmacol 2003; 186(2):110-8 

22. Cizmas L, Barhoumi R, Burghardt RC, Reeves WR, He L, McDonald TJ, Donnelly KC: A comparison of two 

methods for fractionating complex mixtures in preparation for toxicity analysis. J Toxicol Environ Health A 

2003; 66(14):1351-70 

23. Bickham JW, Matson CW, Islamzadeh A, Rowe GT, Donnelly KC, Swartz CD, Rogers WJ, Wickliffe JK, 

Autenrieth RL, McDonald TJ, Politov D, Palatnikov G, Mekhtiev AA, Kasimov R: Editorial: the unknown 

environmental tragedy in Sumgayit, Azerbaijan. Ecotoxicology 2003; 12(6):505-8 

24. Ake CL, Wiles MC, Huebner HJ, McDonald TJ, Cosgriff D, Richardson MB, Donnelly KC, Phillips TD: 

Porous organoclay composite for the sorption of polycyclic aromatic hydrocarbons and pentachlorophenol 

from groundwater. Chemosphere 2003; 51(9):835-44

NAME 

Fackler, John P. 





rburghardt 


Distinguished Professor, Departments of Chemistry 

and Toxicology, Texas A&M University 



DEGREE 


YEAR(s) 


Massachusetts Inst. of Tech., Cambridge, MA 1952 

Valparaiso University, Valparaiso, IN B.A. 1956 Chem., Math, Physics 

Massachusetts Inst. of Tech., Cambridge, MA Ph.D. 1960 Chemistry 

Research Associate, M.I.T., Cambridge, MA 1960 



1987- present Dist. Prof. of Chem. and Tox., Texas A&M University 

1994 Manchot Forschungsprofessur Tech. Univ. Munich 

1994 Bye Fellow, Robinson College U. Cambridge 

1983-91 Dean and Prof. Chem., College of Science, TAMU 

1978-82 Teagle Professor of Chemistry, Case Western Reserve Univ. 

1970-78 Professor CWRU 

1977 Visiting Professor Sidney Sussex College, U. Cambridge 

1972-77 Chairman, Dept. of Chemistry CWRU 

1971 Visiting Professor (month) Indiana U. 

1969 Visiting Assoc. Prof. (3 months) U.C. Santa Barbara 

1964-70 Associate Professor CWRU 

1962-64 Assistant Professor CWRU 

1960-62 Assistant Professor U.C. Berkeley 

Societies, Professional Activities, Honors & Awards: 

2000-present Career Consultant, American Chemical Society 

2002-present Advisory Board PEER 

2003-present Advisory Board, Center for Teaching Excellence 

2003-present Executive committee Faculty Senate, 2003-present 

2002-2005 Executive committee Distinguished Professors 

2002-2005 Quality Enhancement Program Council 

2002-2004 Quality Enhancement Program Council Chair 

2001-2004 Advisory Board, ITS 

2000-2004 Industry University Cooperative Chemistry Program Coordinator 

2000-2003 Executive Committee, Council of Principal Investigators 

2001-2002 Executive Committee, Council of Principal Investigators Chair 

2001 American Chemical Society Award for Distinguished Service to Inorganic Chemistry 

2000 University Distinguished Lecturer 

1990 American Chemical Society, Southwest Regional Award 

1987 American Chemical Society, Cleveland Section, Morley Medal 

1987 Valparaiso University, D.Sc Honoris Causa 

1977 J. S. Guggenheim Fellowship

B. Selected Peer-Reviewed Publications (244 total) 

Mercury(II) Cyanide Coordination Polymer with Dinuclear Gold(I) Amidinate. Structure of the 2-D [Au 2 (2,6- 

Me 2 -formamidinate) 2 ]2Hg(CN) 2 2THF Complex. Ahmed A. Mohamed, Hanan E. Abdou, John P. 

Fackler, Jr., Inorg. Chem., 2006, 45, 11-13. 

Theoretical Aspects of Transition Metal Catalysis. Topics in Organometallic Chemistry, 12. John P. 

Fackler, Jr., J. Am. Chem. Soc., 2006. 128, 2757. 

External heavy-atom effect of gold in a supramolecular acid-base pi stack. Ahmed A. Mohamed, Manal A. 

Rawashdeh-Omary, Mohammad A. Omary, John P. Fackler, Jr., Dalton Transactions, 2005, 15, 2597- 

2602 

Photophysics of supramolecular binary stacks consisting of electron-rich trinuclear Au(I) complexes and 

organic electrphiles. Ahmed A. Mohamed, Manal A. Rawashdeh-Omary, Mohammad A. Omary, John 

P. Fackler, Jr., Coordination Chemistry Reviews, 2005, 249, 1372-1381. 

The Role of F-Centers in Catalysis by Au Supported on MgO. Z. Yan, S. Chinta, Ahmed A. Mohamed, J. P. 

Fackler, Jr., and D.W. Goodman, J. Am. Chem. Soc., 2005, 127, 1604-1605. 

Novel metallamacrocyclic gold(I) thiolate cluster complex: structure and luminescence of [Au9(:- 

dppm)4(:-p-tc)6](PF6)3. Jinhua Chen, Ahmed A. Mohamed, Hanan E. Abdou, Jeanette A. Krause 

Bauer,John P. Fackler, Jr., Alice E. Bruce and Mitchell R. M. Bruce. Chem. Commun., 2005, 1575- 

1577. 

Mixed-Metal Triangular Trinuclear Complexes: Dimers of Gold-Silver Mixed-Metal Complexes from 

Gold(I) Carbenieates and Silver(I) 3,5-Diphenylpyrazolates. Ahmed A. Mohamed, Alfredo Burini, John 

P. Fackler, Jr., J. Am. Chem. Soc., 2005, 127, 5012-5013. 

Synthesis and X-ray Structures of Dinulear and Trinuclear Gold(I) and Dinuclear Gold(II) Amidinate 

Complexes. Hanan E. Abdou, Ahmed A. Mohamed, John P. Fackler, Jr., Inorg. Chem., 2005, 44, 166- 

168 

Photophysics of supramolecular binary stacks consisting of electron-rich trinuclear Au(I) and organic 

electrophiles. Mohammad A. Omary, Ahmed A. Mohamed, Manal A. Rawashdeh-Omary, John P. 

Fackler, Jr., Coordination Chemistry Reviews, 2005, 249, 1372-81. 

Unsupported intermolecular argentophilic interaction in the dimer of trinuclear silver(I) 3,5- 

diphenylpyrazolates. Ahmed A. Mohamed, Lisa M. Perez, and John P. Fackler, Jr., Inorganica Chimica 

Acta, 2005, 358, 1657-1662. 

Main group compounds. Sodium tetrakis(3,5-bis(trifluoromethyl)phenyl)borate, Na[B(3,5-(CF3)2C6H3)4]. 

Daniel L. Reger, Christine A. Little, Jaydeep J. S. Lamba, Kenneth J. Brown, Jennifer R. Krumper, 

Robert G. Bergman, Michael Irwin, John P. Fackler, Jr., Inorganic Syntheses, 2004, 34, 5-8. 

Structures and luminescence of mononuclear and dinuclear base-stabilized gold(I) pyrazolate complexes. 

Ahmed A. Mohamed, Tiffany Grant, Richard J. Staples and John P. Fackler, Jr., Inorganica Chimica 

Acta, 2004, 357, 1761-1766. 

A Detailed Study of the Vapochromic Behavior of {Tl[Au(C6Cl5)2]}n. Eduardo J. Fernandez, Jose M. 

Lopez-de-Luzuriaga, Miguel Monge, Manuel Montiel, M. Elena Olmos and Javier Perez, Antonio 

Laguna, Fernando Mendizabal, Ahmed A. Mohamed and John P. Fackler, Jr., Inorg. Chem., 2004, 43, 

3573-3581. 

Cluster self-assembly of centered cubes of copper(I) with dialkyldithiophosphate ligands. X-ray structures of 

[Cu 8 (DDP) 6 (8-X)]PF 6 (DDP=S 2 P(O i Pr) 2 ; X=Cl or Br) and their relationship to oxide and sulfide centered 

zinc(II) dialkyldithiophosphates, [Zn 4 (DDP) 6 (8-S or O)]. C. W. Liu, Michael D. Irwin, Ahmed A. 

Mohamed, and John P. Fackler Jr., Inorganica Chimica Acta, 2004, 357, 3950-3956. 

Oxidative Addition of Methyl Iodide to Dinuclear Gold(I) Amidinate Complex: Schmidbaur’s 

Breakthrough Reaction Revisited with Amidinates. Hanan E. Abdou, Ahmed A. Mohamed, and John P. 

Fackler, Jr., Zeitschrift fur Naturforschung B, 2004, 59b, 1480-1482. 

{Tl[Au(C6Cl5)2]}n: A Vapochromic Complex. Eduardo J. Fernández, José M. López-de-Luzuriaga, Miguel 

Monge, M. Elena Olmos and Javier Pérez, Antonio Laguna, Ahmed A. Mohamed, and John P. Fackler, 

Jr., J. Am. Chem. Soc., 2003, 125, 2022-23. 

Forty-Five Years of Chemical Discovery Including a Golden Quarter-Century. John P. Fackler, Jr. Inorg. 

Chem., 2002, 41, 6959-72. 

.




NAME 

Richard H. Finnell 


FINNELLR 


Regents Professor 



DEGREE 


YEAR(s) 


University of Oregon, Eugene BS 1975 Biology 

University of British Columbia, Vancouver MSc 1978 Medical Genetics 

Univer. of Oregon Hlth Sci Ctr-Portland PhD 1980 Medical Genetics 

Neurological Sciences Center, Portland Postdoc 1980-81 Neurogenetics 

Universität Zürich, Switzerland Postdoc 1981-82 Embryology 


1982-1988 Assistant Professor, Department of Veterinary and Comparative Anatomy, Pharmacology and 

Physiology, College of Veterinary Medicine, Washington State University, Pullman 

1988-1991 Associate Professor (as above) 

1990-1991 Visiting Professor, Department of Pharmacology, University of Pennsylvania School of 

Medicine, Philadelphia 

1991-1995 Associate Professor, Department of Veterinary Anatomy and Public Health, Texas Veterinary 

Medical College, Texas A&M University, College Station 

1995-1999 Professor and Asst. Department Head, Department of Veterinary Anatomy and Public Health, 

Associate Dean for Research, College Veterinary Medical, Texas A&M University, College 

Station 

1999-2001 Director, Center for Human Molecular Genetics, University of Nebraska Medical Ctr, Omaha, 

NE 

2001-2006 Professor and Director, Institute of Biosciences and Technology, The Texas A&M University 

System Health Science Center, Houston, Texas 

2006-present Margaret M. Alkek Professor, Institute of Biosciences and Technology, The Texas A&M 

University System Health Science Center, Houston, Texas 

2005-present Executive Director and President, The Texas Insitute for Genomic Medicine 

Awards and Other Professional Activities: 

1981 Recipient of Roche Foundation for Scientific Exchange Fellowship 

1982 Recipient of Basil O’Connor Fellowship from the March of Dimes 

1990-1995 Member of Oral Biology and Medicine Study Section, NIH 

1995- Chair, Scientific Advisory Committee-Texas Birth Defects Monitoring Division 

1995- NIH Reviewer’s Reserve 

1997 Faculty Distinguished Achievement Award in Research, Texas A&M University 

2000, 2004 Recipient-Wilson Award for best paper of the year-Teratology Society 

2002- Associate Editor- Birth Defects Research A 

2005- Regents' Professor-Texas A&M University Health Science Center 

2005- Margaret M. Alkek Professor of Medical Genetics 


1. Finnell, RH. 1981. Phenytoin-induced teratogenesis: A mouse model. Science 211:483-484. 

2. Buehler, BA, D Delimont, M vanWaes, and RH Finnell. 1990. Prenatal determination of risk of the fetal 

hydantoin syndrome. N Engl J Med 322:1567-1572.

3. Eberwine, JH, H Yeh, K Miyashiro, Y Cao, S Nair, RH Finnell, M Zettle, and P Coleman. 1992. Analysis of 

gene expression in single neurons. Proc Soc Natl Acad Sci USA 89:3010-14. 

4. Piedrahita, JA, B. Oetama, G.D. Bennett, J. van Waes, B.A. Kamen, J. Richardson, S.W. Lacey, R.G.W. 

Anderson, R.H. Finnell. 1999. Inactivation of the folate binding protein genes disrupts neural tube closure. 

Nature Genetics.23:228-232. 

5. Spiegelstein, O., Eudy, J.D. and Finnell, R.H. 2000. Identification of two novel folate receptor genes in 

humans and mouse. Gene. 258:117-125 

6. Finnell, R.H. and J. Burn. 2001. Effect of anti-epileptic drugs on intrauterine growth. The Lancet. ii:1537- 

1538. 

7. Finnell, R.H., Gelineau-van Waes, J., Eudy, J.D., Rosenquist, T.H. 2002. Genetic Regulation of 

Susceptibility to Environmentally Induced Birth Defects. Ann. Rev. Pharmacol & Toxicol. 42:181-208. 

8. Spiegelstein, O., Cabrera, R.M., Bozinov, D., Wlodarczyk, B., Finnell, R.H. 2004. Folate-regulated changes 

in gene expression in the anterior neural tube of folate binding protein-1 deficient murine embryos. 

Neurochem. Res. 6:1105-1112. 

9. Spiegelstein, O., Mitchell, L.E., Merriweather, M., Wicker, N.J., Zhang, Q., Lammer, E.J. and Finnell, R.H. 

2004. Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical 

form, dose, and timing of maternal folate supplementation. Devel. Dynamics. 231:221-231. 

10. Kappen, C., Mello, M.A., Finnell, R.H., and Salbaum, J.M. 2004. Folate modulates Hox gene-controlled 

skeletal phenotypes. Genesis 39:155-166. 

11. Tang, L.S., Wlodarczyk, B.J., Santillano, D.R., Miranda, R.C. and Finnell, R.H. 2004. Developmental 

consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res. 

70:449-458. 

12. Lammer E.J., Shaw G.M., Iovannisci DM, Finnell R.H. 2004. Periconceptional multivitamin intake during 

early pregnancy, genetic variation of acetyl-N-transferase (NAT1), and risk for orofacial clefts. Birth Def 

Res A 70:846-52. 

13. Birn, H., Spiegelstein, O., Christensen, E.I. and Finnell, R.H. 2005. Renal tubular reabsorption of folate 

mediated by folate binding protein 1. Am.J.Soc. Nephrol. 16:608-615. 

14. Ma, D., Finnell, R.H., Davidson, L.A., Callaway, E.S., Spiegelstein, O., Piedrahita, J.A., Salbaum, J.M., 

Kappen, C., Weeks, B., James, S.J., Bozinov, D., Lupton, J.R., and Chapkin, R.S. 2005. Folate transport 

gene inactivation in mice increases sensitivity to colon carcinogenesis. Cancer Res. 65:887-897. 

15. Massa, V., Cabrera, R.M., Menegola, E., Bozinov, D., Giavini, E., and Finnell, R.H. 2005. Valproic acid 

induced skeletal malformations: Associated Gene Expression Cascades. Pharmacogenetics Genomics 

15:787-800. 

16. Lammer, E.J., Shaw, G.M., Iovannisci, D.M. and Finnell, R.H. 2005. Maternal smoking, genetic variation 

of glutathione s-transferases, and risk of orofacial clefts. Epidemiology 16:698-701. 

17. Abdelrahim, M., Ariazi, E., Kyounghyun, K., Khan, S., Barhoumi, R., Burghardt, R., Liu, S., Hill, D., Finnell, 

R., Wlodarczyk, B., Jordan, V.C., and Safe, S. 2006. 3-Methylcholanthrene and other aryl hydrocarbon 

receptor agonists directly activate estrogen receptor alpha. Cancer. Res. 66:2459-2467. 

18. Wlodarczyk, B.J., Tang, L.S., Triplett, A., Aleman, F, and Finnell, R.H. 2006. Spontaneous neural tube 

defects in Splotch mice supplemented with selected micronutrients. Toxicol. Appl. Pharmacol. 213:55-63. 

19. Meador, K.J., Baker, G.A., Finnell, R.H., Kalayjian, L.A., Liporace, J.D., Loring, D.W., Pennell, P.B., Smith, 

J.C., and Wolf, M.C. for the NEAD Study Group. 2006. Differential Effects of in Utero Exposure to 

Antiepileptic Drugs: Serious Adverse Outcomes in Children. Neurology. 67(3):407-12. 

20. Blom, H.J., Shaw, G.M., den Heijer, M. and Finnell, R.H. 2006. Neural tube defects and folate: case far 

from closed. Nat. Neuroscience. 7:724-731. 

21. Rosenquist, T.H. and Finnell, R.H. 2007. Another key role for the cardiac neural crest in heart 

development. Am. J. Physiol. 2006 Nov 10; [Epub ahead of print].




NAME 

Harvey, Roger B. 



Veterinary Medical Officer 



DEGREE 


YEAR(s) 


Texas A&M University B.S. 1968 Veterinary Science 

Texas A&M University D.V.M. 1969 Veterinary Medicine 

Texas A&M University M.S. 1983 Veterinary Toxicology 

A. Posititions and Honors 

Posititions and Employment 

1969-1973 Captain, U.S. Army Veterinary Corps 

1974-1975 Assistant Professor, Department of Agriculture, Southwest Texas State University, 

San Marcos, TX 

1973-1975 Private Practitioner, Tickle Animal Hospital, San Marcos, TX 

1975-1978 Extension Poultry Veterinarian, Texas Agricultural Extension Service, Texas A&M 


1978-1981 Director of Technical Services, Agri-Bio Corp., Gainsville, GA 

1981-1985 Research Associate, Veterinary Physiology and Pharmacology, Texas 

A&M University, College Station, TX 

1985-Present Veterinary Medical Officer, U.S. Department of Agriculture, Agricultural Research 

Service, Southern Plains Agricultural Research Center, College Station, TX; 

Professor, Faculty of Toxicology; Adjunct Professor, Veterinary Integrative 

Biosciences; Professor, Graduate Faculty; Faculty Member, Center for Food Safety, 

Institute for Food Science and Engineering; Texas A&M Univ., College Station, TX 


American Veterinary Medical Assoc., American Assoc. of Swine Practitioners, American Assoc. of 

Avian Pathologists (AAAP), American Assoc. of Veterinary Laboratory Diagnosticians (AAVLD), 

American Academy of Veterinary and Comparative Toxicology (AAVCT), U.S. Animal Health Assoc., 

World Veterinary Poultry Assoc., World Veterinary Medical Assoc., Society Experimental Biology and 

Medicine 

Chair, Toxic and Miscellaneous Infectious Diseases Committee, AAAP, 1991-94 

Food Safety Committee, AAAP, 1994-97 

Animal Care and Use Committee, Food Animal Protection Research Lab., 1990-96 

Controlled Substances Officer, SPARC, 1993-present 

Executive Council, AACVT, 1992-95 

Section Editor: Mycotoxins and Natural Toxins, Quintessence, 1994-95 

Salmonella Working Group, National Pork Board, 1998-present 

Salmonella Intervention Committee, National Pork Board, 1998-present

Reviewer: Pre-Harvest Food Safety Research Proposals, National Pork Board, 1999-present 

NAPES Committee, National Pork Board, 2002-present 

Reviewer: Research Proposals, Food Safety, NRI, USDA-CSREES, 1998-present 

Editorial Review Board, Food Additives and Contaminants, 2000-present 

Honors 

1991 Early Career Scientist of the Year, U.S.D.A., Southern Plains Area 

1991 Daniel E. Salmon, Federal Veterinarian of the Year Award 

1989 Engelhard Corporation Award of Merit for Research on NovaSil, 

1976-77 Member, Phi Sigma Honorary Biological Society, 1976-77 

1964-69 Distinguished Student, Texas A&M University 

B. Selected Peer-Reviewed Publications (in chronological order). 

(Publications selected from over 150 peer-reviewed publications) 

Callaway, T.R., Staki, C.H., Edrington, T.S., Genovese, K.J., Lincoln, L.S., Anderson, R.C., Lonergan, S.M., 

Poole, T.L., Harvey, R.B., Nisbet, D.J. Colicins inhibit growth of Escherichia coli O157:H7 but not 

Salmonella in vitro. J. Food Prot. 67:2603-2607. 2004. 

Callaway, T.R., Anderson R.C., Edrington, T.S., Genovese, K.J., Poole, T.L, Harvey, R.B., Nisbet, D.J., and 

Dunkley, D.S. Probiotics, Vaccines, and Other Intervention Strategies. Pp. 192-2213. In: J. Sofos (ed.). 

2004. (Book Chapter) 

Jung, Y.S., Anderson, R.C., Callaway, T.R., Edrington, T.S., Genovese, K.J., Harvey, R.B., Poole, T.L., and 

Nisbet, D.J. Inhibitory activity of 2-nitropropanol against select foodborne pathogens in vitro. Lett. Appl. 

Microbiol. #9:471-476. 2004. 

Harvey, R.B., Anderson, R.C., Genovese, K.J., Callaway, T.R., and Nisbet, D.J. Use of competitive exclusion 

to control enterotoxigenic strains of E. coli in weaned pigs. J. Anim. Sci. 83(Supp. E):E44-E47. 2005. 

Scott, H.M., Campbell, L.D., Harvey, R.B., Bischoff, K.M., Alali, W.Q., Barling, K.S., and Anderson, R.C. 

Patterns of antimicrobial resistance among commensal Escherichia coli isolated from multi-site housing 

and worker cohorts of human and swine. Foodborne Pathogens and Disease 2:24-37. 2005. 

Ziprin, R.L., Hume, M.E., Andrews, K., Droleskey, R.E., Harvey, R.B., and Sheffield, C.L. An atypical 

Campylobacter coli exhibiting unusual morphology. Current Microbiol. 51:1-4. 2005. 

Callaway, T.R., Morrow, J.L., Poole, T.L., Wallace, F.M., Anderson, R.C., Dowd, S.E., Edrington, T.S., 

Genovese, K.J., Byrd II, J.A., and Harvey, R.B. Environmental prevalence and persistence of E. coli, 

coliforms, and Salmonella spp. in outdoor swine wallows. Foodborne Path. Dis. 2:263-273. 2005. 

Campbell, L.D., Scott, H.M., Bischoff, K.M., Anderson, R.C., and Harvey, R.B. Prevalence of Class I integrons 

and AMR gene cassettes among enteric bacteria found in multi-site group-level cohorts of humans and 

swine. J. Food Prot. 68:141-145. 2005. 

Anderson, R.C., Harvey, R.B., Byrd, J.A., Callaway, T.R., Genovese, K.J., Edrington, T.S., Jung, Y.S., 

McReynolds, J.L., and Nisbet, D.J. Novel preharvest strategies involving the use of experimental chlorate 

preparations and nitro-based compounds to prevent colonization of food-producing animals by foodborne 

pathogens. Poult. Sci. 84:649-654. 2005. 

Poole, T.L., Hume, M.E., Campbell, L.D., Scott, H.M., Alali, W.Q., and Harvey, R.B. Characterization of 

vancomycin-resistant Enterococcus faecium isolated from community waste water from a semi-closed 

agri-food system in Texas. Antimicrob Agents Chemother 49:4382-4385. 2005. 

Sheffield, C.L., Andrews, K., Harvey, R.B., Crippen, T.C., and Nisbet, D.J. Dereplication by automated 

ribotyping of a competitive exclusion culture bacterial isolate library. J. Food Prot. 69:81-85. 2006. 

Anderson, R.C., Genovese, K.J., Harvey, R.B., Callaway, T.R., and Nisbet, D.J. Preharvest food safety 

applications of competitive exclusion cultures and probiotics. Pp. 273-284. In: Probiotics in Food Safety 

and Human Health. Goktepe, I., Juneja, V.J., and Ahmedna, M. (ed.), Taylor and Francis, New York, 

USA. 2006. (Book Chap) 

Harvey R.B., Andrews K., Droleskey, R.E., Kansagra, K.V., Stoll, B., Burrin, D.G., Sheffield, C.L., Anderson, 

R.C., and Nisbet, D.J. Qualitative and quantitative comparison of gut bacterial colonization in enterally 

and parenterally fed neonatal pigs. Curr. Issues Intest. Microbiol. 7:61-64. 2006.


Give the following information for the key personnel and consultants and collaborators. Begin with the principal 

investigator/program director. Photocopy this page for each person. 

NAME 

Larry Johnson 


Professor, Faculty of Toxicology 


INSTITUTION AND LOCATION DEGREE YEAR CONFERRED FIELD OF STUDY 

North Carolina State Univ., Raleigh 

Virginia P.I. and State U., Blacksburg 

Colorado State Univ., Fort Collins 

Univ. Texas Health Sci. Ctr., Dallas 

B.S. 

M.S. 

Ph.D. 

Postdoctoral 

May 1971 

Dec. 1974 

June 1978 

Animal Science 

Reprod Physiol 

Reprod Physiol 

Reprod Biology 

PROFESSIONAL EXPERIENCE: 

Asst. Professor in Cell Biology, Univ, of Texas Health Science Center - Dallas, 1980-1987. 

Assoc. Professor, Division of Cell Biology & Ultrastructure, Department of Veterinary Anatomy and Public 

Health, College of Veterinary Medicine, Texas A&M University, College Station, Texas. 1987-1992. 

Professor, Faculty of Toxicology, Center for Environmental and Rural Health, Department of Veterinary 

Anatomy and Public Health, College of Veterinary Medicine, Texas A&M University, College Station, 

Texas. 1992-present. 

AWARDS AND HONORS: 

NIH New Investigator Research Award, 1983-1986; 1988 Young Andrologist Award, from the American Society 

of Andrology; Invited speaker (Spermatogenesis, Animal Species and Humans) at 1988 International 

Symposium on Gamete Physiology, Serono Symposia, USA; Invited speaker (Spermatogenesis in humans 

and animal species), 1990 Japan Society of Andrology; Invited speaker (Spermatogenesis in domestic animals 

and approaches to its enhancement) at the XI Brazilian Congress of Animal Reproduction 1995; Invited 

speaker (Efficiency of Spermatogenesis in Humans), College of Medicine, University of Utrecht, The 

Netherlands, 1996; Invited speaker (Transplantation on Spermatogenesis: Sperm Decline in Humans), La 

Federation Frankaise Pour L=etude de la Reproduction, 1997; Research Career Development Award 1991- 

1996; Editorial Boards of Biology of Reproduction (1989-1995), of AGE (1992-1995), and Journal of Andrology 

(1997-present); University-level teaching award from TAMU Honors Undergraduate Program, 1996; Collegelevel 

Teaching Award in Biomedical Science Undergraduate Program, 1999. Local Texas A&M University 

Chapter of Sigma Xi Science Communication Award, 2001. 

FEDERAL GOVERNMENT PUBLIC ADVISORY COMMITTEE: 

Served on Advisory Panel of The Office of Technology Assessment (OTA) to the United States Congress for 

the assessment "Reproductive Hazards in the Workplace" 1984; Speaker at the EPA workshop on "Sperm 

Measures and Reproductive Success," 1988; USDA Panel for Competitive Research in "Reproduction of 

Animals," 1992; NIA Panel for a Program of Projects in Aging and Reproduction, 1992, 1993, and 1994; NIH 

ad hoc Panel Member of Biochemical Endocrinology Study Section 1993; National Review Panel (NIEHS) for 

Use of Frog Eggs for Toxicant Screening; National Review Panel NIOSH Study Section of Centers for 

Agricultural Disease and Injury Research, Education, and Prevention, 2001. 

PUBLICATIONS: (Selected from 104 original, 10 review articles or book chapters, and 1 book co-author) 

2000 Blanchard, T.L., L. Johnson, and A.J. Roser. Increased germ cell loss rates and poor semen quality in 

stallions with idiopathic testicular degeneration. J. of Equine Vet. Sci. 20:263-265. 

2000 Blanchard,T., D. Varner, L. Johnson, J. Roser, J. Hill, and C. Miller. Testicular and hormonal changes 

in stallions with thermally induced testicular degeneration. J. Reprod. Fertil. 56:51-59. 

2000 Varner, D.D., T.L. Blanchard, S.P. Brinsko, C.C. Love, T.S. Taylor, and L. Johnson. Techniques for 

evaluating selected reproductive disorders of stallions. Am. Reprod. Sci. 60:493-509.

2000 Silber, J.J., L. Johnson, G. Verheyen, and A.V. Steirteghem. Round spermatid injection. Fertil. Steril. 

73:897-900. 

2000 Johnson, L., D.D. Varner, M.E. Roberts, T.L. Smith, G.E. Keillor, and W.L. Scrutchfield. Efficiency of 

spermatogenesis: a comparative approach. Anim. Reprod. Sci. 60:471-480. 

2001 Johnson, L., C. Staub, W.B. Neaves, and R. Yanagimachi. Live human germ cells in the context of 

their developmental steps of spermatogenesis and spermatogenic stages of the cycle. Human Reprod. 

16:1575-1582. 

2001 Wilker, C.E., N.H. Ing, T.H. Welsh, Jr., and L. Johnson. Testicular grafts produce testosterone and 

express Sertoli cell genes. Adv. Reprod. 5:113-148. 

2001 Blanchard, T.L., L. Johnson, D.D. Varner, S.P. Rigby, S.P. Brinsko, C.C. Love, and C. Miller. Low daily 

sperm output per ml of testis as a diagnostic criteria for testicular degeneration in stallions. J. Equine 

Vet. Sci. 21(1):11, 33-35. 

2002 Staub, C., V.B. hardy, R.E. Chapin, M.W. Harris, and L. Johnson. The hidden effect of 

estrogenic/antiandrogenic methoxychlor on spermatogenesis. Toxicology and Applied Pharmacology 

180:129-135. 

2002 Laughlin, A.M., D.W. Forrest, D.D. Varner, T.L. Blanchard, C.C. Love, T.H. Welsh, Jr., L. Johnson, and 

N.H. Ing. DNA microarray analysis of gene expression in testicular tissue of stallions. Theriogenology 

58:413-416. 

2002 Staub, C., N.L. Heniger, C.L. Donnelly, D.W. Forrest, T.L. Blanchard, C.C. Love, D.D. Varner, and L. 

Johnson. Apoptosis during the initiation of equine spermatogenesis. Theriogenology 58:367-372. 

2002 Fielden, M.R., R.G. Halgren, C.J. Fong, C. Staub, L. Johnson, K. Chou, and T.R. Zacharewski. 

Gestational and lactational exposure of male mice to diethylstilbestrol causes long-term effects on the 

testis, sperm fertilizing ability in vitro, and testicular gene expression. Endocrinology 143(8):3044- 

3059. 

2002 Welsh, Jr., T.H., T.M. Bryan, L. Johnson, S.P. Brinsko, S.R. Rigby, C.C. Love, D.D. Varner, D.W. 

Forrest, and T.L. Blanchard. Characterization of sperm and androgen production by testes from control 

and ponazuril-treated stallions. Theriogenology. 58:389-392. 

2002 Fielden, M.R., R.G. Halgren, C.J. Fong, C. Staub, L. Johnson, K. Chou, and T.R. Zacharewski.. 

Gestational and lactational exposure of male mice to diethylstilbestrol causes long-term effects on the 

testis, sperm fertilizing ability in vitro, and testicular gene expression. Endocrinology. 143(8):3044- 

3059. 

2003 Johnson, L., C. Staub, R.L. Silge, M.W. Harris, and R.E. Chapin. The pesticide methoxychlor given 

orally during the perinatal/juvenile period, reduced the spermatogenic potential of males as adults by 

reducing their Sertoli cell number. Reproduction, Nutrition and Development 42:573-580. 

2004 Froment, P., C. Staub, S. Hembert, C. Pisselet, M. Magistrini, B. Delaeu, D. Seurin, J.E. Levine, L. 

Johnson, M. Binoux, and P. Monget. Reproductive abnormalities in hIGFBP-1 transgenic male mice. 

Endocrinology 145:2080-2091. 

2004 Ing, N.H., A. Laughlin, D.D. Varner, T.H. Welsh, Jr., D.W. Forrest, T.L. Blanchard, and L. Johnson. 

Gene expression in the spermatogenically inactive “dark” and the maturing “light” testis tissue of the 

prepubertal colt. J. Androl. 25:535-544. 

2005 Lindner, J.R., G.J. Wingenback, J. Harlin, Y. Li, I. Lee, R. Jackson, L. Johnson, W. Klemm, J. Hunter, J. 

Kracht, and D. Kocheaver. “Students’ beliefs about science and sources of influence affecting science 

career choice. NACTA Journal, 48(2), 2-7. 

2006 Heninger, N.L., T.L. Blanchard, D.W. Forrest, D. Varner, and L. Johnson. 200X. Germ cell apoptosis in 

the testis of normal stallions. Theriogenology (in press). 

2006 Heninger, N.L., T.L. Blanchard, D.W. Forrest, D. Varner, J.F. Roser, and L. Johnson. 200X. 

Relationship of germ cellapoptosis to spermatogenic efficiency in stallions with reduced semen quality. 

Theriogenology (in press).




NAME Ann B. Kier POSITION TITLE Professor 




University of Texas, Austin, TX B.A. 1971 Zoology 

Texas A&M University, College Station, TX B.S., D.V.M. 1974 Veterinary Medicine 

University of Missouri, Columbia, MO Ph.D. 1979 Comparative Pathology 

A. POSITIONS: NIH Postdoctoral Fellow and Resident in Comparative Pathology and Laboratory Animal 

Medicine, Research Animal Diagnostic and Investigative Laboratory, University of Missouri, Columbia, MO. 

1976-1979; Assistant Professor, Pathology, VMDL, Department of Veterinary Pathology, University of Missouri, 

Columbia, MO, 1979-1984; Associate Professor, Pathology and Microbiology, VMDL, University of Missouri, 

Columbia, MO, 1984-1987; Associate Professor, Department of Pathology and Laboratory Medicine; University 

of Cincinnati College of Medicine, Cincinnati, OH, 1987-1991; Professor and Director, Division of Comparative 

Pathology, Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, 

Cincinnati, OH; 1991-1993; Professor and Head, Department of Pathobiology, TVMC, Texas A&M University, 

College Station, TX, 1993-2005; Director, Transgenic Facility Core, Texas A&M University, 1995-present; 

Professor, Department of Pathobiology, TVMC, Texas A&M University, College Station, TX, 2005-present. 

HONORS: NIH Postdoctoral Fellowship; Diplomate, American College of Laboratory Animal 

Medicine; American Society of Investigative Pathology, FASEB; ASBMB, FASEB; NIH Special 

Emphasis Research Career Development Award (SERCA) in Laboratory Animal Science (KO1), 

1980-1985; Administrative Award, Women’s Faculty Network, Texas A&M University, 2004; NIH/NCI 

Immunobiology Contract Review Study Section, 1986-1988; NIH Comparative Medicine Study 

Section,1992-1996; Two Thousand Notable American Women, 2000, 2001; Rhodes Faculty Abroad 

Program, 2002; Editorial Board, Journal of Comparative Medicine, 1998-present; ad hoc Study 

Sections, NIEHS, Mutant Mouse Resources, NCRR, 1997-present. 

B. SELECTED REPRESENTATIVE PUBLICATIONS (from 125 total) 

Mucenski ML, McLain K, Kier AB, Swerdlow SH, Schreiner CM, Miller TA, Peitryga DW, Scott WJ, Potter SS: A 

functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 65: 677-689, 1991. 

Shull M, Ormsby I, Kier AB, Pawlowski S, Diebold R, Yin M, Sidman C, Annuziata N, Doetschman T: Targeted 

disruption of murine TGFβ1 gene results in multifocal inflammatory disease. Nature 359: 693-699, 1992. 

Boivin GP, O’Tolle BA, Ormsby IE, Diebold RJ, Eis MJ, Doetschman TC, Kier AB: Onset and progression of 

pathologic lesions in TGF1-deficient mice. J Pathology 146: 276-288, 1994. 

Muthuchamy M, Grup I, Grup G, O’Toole B, Kier A, Boivin G, Neumann J, Wieczorek D: Molecular and 

physiological effect of overexpressing striated muscle tropomyosin in heart. J Biol Chem 270: 30593- 

30603, 1995. 

Ess K, Chen H, Kier A, Brackenbury R: Suppression of tumorigenicity, but not invasion, in glioblastoma/ HeLa 

cell hybrids. J Cell Physiol 162: 3431-347, 1995. 

Kier AB, Foxworth B: Gene targeting and transgenesis: An overview of the techniques and approaches to 

analysis of induced mutants. Toxicologic Pathology, 23: 737-738, 1995. 

Gossett R, Frolov AA, Roths JB, Behnke WD, Kier AB, Schroeder F: Fatty acyl CoA binding proteins in 

mammalian tissues. Lipids 31: 895-918, 1996. 

Fontaine RN, Gossett RE, Schroeder F, O’Toole BA, Doetschman T, Kier AB: Liver and intestinal FABPs in 

control and TGFβ gene targeted deficient mice. Mol Cell Biol 159: 149-153, 1996. 

Roths JB, Foxworth WB, Montgomery CA, Kier AB: Assessment of targeted and spontaneous mutations in 

mouse as experimental models of inherited disease. Lab An Science 49: 12-34, 1999. 

8

Starodub O, Atshaves B, Schoer J, Roths J, Kier A, Schroeder F: Sterol Carrier Protein-2 

immunocolocalization in ER and stimulation of phospholipid formation. Am J Physiol 279:C1259- 

C1269, 2000. 

Schroeder F, Atshaves B, Starodub O, Boedeker A, Smith R, Roths J, Foxworth W, Kier A: Expression 

of L-FABP alters growth and differentiation of ES cells. Mol Cell Biochem 219:127-138, 2001. 

Gallegos A, Atshaves B, Storey S, Starodub O, Petrescu A, Huang H, McIntosh A, Martin G, Chao H, 

Kier AB, Schroeder F: Gene structure, intracellular localization, and functions of SCP-2. Prog Lip 

Res 40: 498-563, 2001. 

Schroeder F, Gallegos AM, Atshaves BP, Storey SM, McIntosh AL, Petrescu AD, Huang H, 

Starodub O, Chao H, Yang Y, Frolov A, Kier AB: Recent advances in membrane microdomains: 

Rafts, caveolae, and intracellular cholesterol trafficking. Exp. Biol. Med. 226:873-890,2001. 

Gallegos A, Atshaves B, Storey S, Schoer J, Kier A, Schroeder F: Molecular and fluorescent sterol 

approaches to probing lysosomal membrane lipid dynamics. Chem. Phys. Lip.116:19-38, 2002. 

Huang H, Starodub O, McIntosh A, Kier A, Schroeder F: L-FABP targets fatty acids to nucleus: real time 

confocal and multiphoton fluorescence imaging in living cells. J. Biol. Chem. 277:29139-29151, 2002. 

Chao H, Martin G, Russell W, Waghela S, Russell D, Schroeder F, Kier AB: Membrane charge & curvature 

determine interaction with ACBP and fatty acyl CoA targeting. Biochemistry 41:10540-10553, 2002. 

Petrescu AD, Hertz R, Bar-Tana J, Schroeder F, Kier AB: Ligand specificity and conformational dependence of 

the hepatic nuclear factor-4α (HNF-4α). J. Biol. Chem. 277:23988-23999, 2002. 

Chao H, Zhou M, McIntosh A, Schroeder F, Kier A: ACBP and cholesterol differentially alter fatty acyl 

CoA utilization by microsomal acyl CoA:cholesterol acyltransferase. J. Lip. Res. 44:72-83, 2003. 

Petrescu AD, Payne HR, Boedecker A, Chao H, Hertz R, Bar-Tana J, Schroeder F, Kier AB: Physical and 

functional interaction of ACBP with HNF-4α. J. Biol. Chem. 278:51813-51824, 2003. 

Atshaves B, Gallegos A, McIntosh A, Kier A, Schroeder F: SCP-2 selectively alters lipid composition and 

cholesterol dynamics of caveolae/lipid raft vs nonraft domains in L-cell plasma membranes. Biochemistry 

42:14583-14598, 2003. 

Huang H, Starodub O, McIntosh A, Atshaves B, Woldegiorgis G, Kier AB, Schroeder F: L-FABP colocalizes 

with PPARα and enhances ligand distribution to nuclei of living cells. Biochemistry 43:2484-2500, 2004. 

Atshaves BP, Payne HR, McIntosh AL, Tichy SE, Russell D, Kier AB, Schroeder F: Sexually dimorphic 

metabolism of branched-chain lipids in C57Bl6/6J mice J. Lip. Res. 45:812-830, 2004. 

Zhou M, Parr RD, Petrescu AD, Payne HR, Atshaves BP, Kier AB, Ball JM, Schroeder F: Sterol carrier protein- 

2 directly interacts with caveolin-1 in vitro and in vivo. Biochemistry 43:7288-7306, 2004. 

Atshaves B, McIntosh A, Payne H, Mackie J, Kier A, Schroeder F: Effect of branched-chain fatty acid on lipid 

dynamics in mice lacking the L-FABP gene. Am. J. Physiol. 288:C543-C558, 2005. 

Petrescu AD, Hertz R, Bar-Tana J, Schroeder F, Kier AB: Role of regulatory F-domain in Hepatocyte 

Nuclear Factor-4α ligand specificity. J. Biol. Chem. 280:16714-16727, 2005. 

Schroeder F, Huang H, Hostetler HA, Petrescu AD, Hertz R, Bar-Tana J, Kier AB: Stability of fatty 

acyl CoA thioester ligands of HNF4α and PPARα. Lipids 40:559-568, 2005. 

Hostetler H, Petrescu A, Kier AB, Schroeder F: PPARα interacts with high affinity and is 

conformationally responsive to endogenous ligands. J. Biol. Chem. 280:18667-18682, 2005. 

Huang H, Atshaves BP, Frolov A, Kier AB, Schroeder F: Acyl-CoA binding protein expression alters 

liver fatty acyl CoA metabolism. Biochemistry 44:10282-10297, 2005. 

Martin GG, Atshaves BP, McIntosh AL, Mackie J, Kier AB, Schroeder F: L-FABP gene ablation alters liver bile 

acid metabolism in male mice. Biochem. J., 391:549-560, 2005. 

Martin GG, Atshaves BP, McIntosh A, Mackie J, Kier AB, Schroeder F: L-FABP gene ablation induces 

hypercholesterolemia in cholesterol-fed female mice. Am. J. Physiol. 290:G36-G48, 2006. 

8




NAME 

Gladys Yi-Ping Ko 


Assistant Professor, Department of Veterinary 

Integrative Biosciences, Texas A&M University 


GLADYSK 



DEGREE 


YEAR(s) 


National Cheng-Kung University, Taiwan, R.O.C. B.S. 1985-1989 Biology 

National Yang-Ming Medical College, Taiwan, R.O.C. M.S. 1989-1991 Anatomical Sciences 

Kent State University affiliated with Northeastern Ohio 

Universities College of Medicine, Kent, Ohio. 

Dept. Neurobiology and Anatomy, University of Texas- 

Houston Medical School, Houston, Texas. 

Dept. Biology and Biochemistry, University of Houston, 

Houston, Texas. 

Ph.D. 1992-1996 Biomedical Sciences 

Postdoc 1996-1999 Neuroscience 

Postdoc 1999-2004 

Neuroscience / Circadian 

Biology 



1991-1992 Research Assistant, Dr. Hwa-Min Hwang’s Laboratory, Department of Anatomy, 

Chung Gung Medical College, Taiwan, R.O.C. 

1996-1999 Postdoctoral Research Fellow, Dr. Paul Kelly’s Laboratory, Department of Neurobiology and Anatomy, 

University of Texas-Houston Medical School, Houston, TX. 

1999-2000 Postdoctoral Fellow II, Dr. Stuart Dryer’s Laboratory, Department of Biology and Biochemistry, University 

of Houston, Houston, TX. 

2000-2004 Research Associate, Dr. Stuart Dryer’s Laboratory, Department of Biology and Biochemistry, University of 

Houston, Houston, TX. 

2004-present Assistant Professor, Department of Veterinary Integrative Biosciences, Texas A&M University, College 

Station, TX. 


1989-1992 The Association of Anatomists of Taiwan, R.O.C. 

1990-present The Society for Neuroscience. 

2005-present Association for Research in Vision and Ophthalmology (ARVO) 

Membership on University Faculties 

2004-present Member, Graduate Faculty, Texas A&M University. 

2004-present Member, Interdisciplinary Faculty of Neuroscience, Texas A&M University. 

2004-present Member, Interdisciplinary Faculty of Toxicology, Texas A&M University. 

2004-present Member, Center for Research on Biological Clocks, Texas A&M University. 

2006-present Member, Center for Environmental and Rural Health, Texas A&M University. 


1989 Annual Scientific Research Award, National Cheng-Kung University, Taiwan, R.O.C. 

1989-1991 Graduate Student Scholarship Award, National Yang-Ming Medical College, Taiwan, R.O.C. 

1990 C. Yin, M.D. Memorial Scholarship Award, National Yang-Ming Medical College, Taiwan, R.O.C. 

1993-1994 Tuition Scholarship, Northeastern Ohio Universities College of Medicine, OH. 

1994-1996 Teaching Assistantship, Northeastern Ohio Universities College of Medicine, OH. 

1997-1999 NIH Training Grant, Department of Neurobiology and Anatomy, University of Texas-Houston Medical 

School, Houston, TX.

2001-2004 NIH Individual National Research Service Award (NIH F32 EY 13920), Houston, TX. 

B. Selected peer-reviewed publications. 

Research papers: 

Chae, K.-S., Ko, G. Y.-P.* and Dryer, S. E. Tyrosine phosphorylation of cGMP-gated ion channels is under circadian 

control in chick retina photoreceptors. IOVS, 48:901-906, 2006. (* Ko is the co-first author and corresponding 

author.) 

Ko, G.Y.-P., Ko, M.L. and Dryer, S.E. Circadian and cAMP-dependent modulation of retinal cone cGMP-gated channels 

does not require protein synthesis or calcium influx through L-type channels. Brain Res. 1021: 277-280; 2004. 

Ko, G.Y.-P., Ko, M.L. and Dryer, S.E. Circadian regulation of cGMP-gated channels of verbebrate cone photoreceptors: 

Role of cAMP and Ras. J. Neuroscience, 24:1296-1304; 2004. 

Ko, G.Y.-P., Ko, M.L. and Dryer, S.E. Circadian phase-dependent modulation of cyclic GMP-gated channels of cone 

photoreceptors by dopamine and D2 agonists. J. Neuroscience, 23: 3145-3153; 2003. 

Ko, G.Y.-P., Ko, M.L. and Dryer, S.E. Circadian regulation of cGMP-gated cationic channels of chick retinal cones: Erk 

MAP kinase and Ca 2+ /calmodulin-dependent protein kinase II. Neuron, 29: 255-266; 2001. 

Ko, G.Y.-P., Ko, M.L. and Dryer, S.E. Developmental expression of retinal cone cGMP-gated channels: Evidence for 

rapid turnover and trophic regulation. J. Neuroscience, 21: 221-229; 2001. 

Ko, G.Y. and Kelly, P.T. Nitric oxide acts as a postsynaptic signaling molecule in calcium/calmodulin-induced synaptic 

potentiation in hippocampal CA1 pyramidal neurons. J. Neuroscience, 19: 6784-6794; 1999. 

Ko, G.Y.-P., Brown, L.M., and Teyler, T.J. The effects of anticonvulsant drugs-phenobarbital, phenytoin, and valproic acid 

on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus. Brain Res. Bull. 42: 297-302; 1997. 

Lee, G.Y.-P.; Brown, L.M. and Teyler, T.J. The effects of anticonvulsant drugs on long-term potentiation (LTP) in the rat 

hippocampus. Brain Res. Bull. 39: 39-42; 1996. 

Brown, L.M.; Lee, G.Y.-P. and Teyler, T.J. Anti-epileptics inhibit cortical NMDA evoked [ 3 H]-norepinephrine efflux. Eur. J. 

Pharm. 254: 307-309; 1994. 

Lee, G.Y.-P.; Chen, S.-T. and Shen, C.-L. Autoradiographic study of the retinal projections on the Chinese Pangolin, 

Manis pentadactyla. Brain, Behavior and Evolution 37: 104-110; 1991. 

Review papers (including book chapters): 

Wang, J.-H., Ko, G.Y.P., and Kelly, P.T. Cellular and molecular bases of memory: synaptic and neuronal plasticity. J. 

Clin. Neurophysiol. 14: 264-293; 1997. 

Teyler, T.J.; Cavus, I.; Coussens, C.; DiScenna, P.; Grover, L.; Lee, Y.-P. and Little, Z. The multideterminant role of 

calcium in synaptic plasticity. Hippocampus 4: 623-634; 1994. 

Teyler, T.J.; Cavus, I.; Coussens, C.; DiScenna, P.; Grover, L.; Lee, Y.-P. and Little, Z. Advances in understanding the 

mechanisms underlying synaptic plasticity. J. Neurosci. Meth. A8; 1994. 

Teyler, T.J.; Cavus, I.; Coussens, C.; DiScenna, P.; Grover, L.; Lee, Y.-P. and Little, Z. Advances in understanding the 

mechanisms underlying synaptic plasticity. In: Brain Slices in Basic and Clinical Research, A. Schurr and B. 

Rigor eds., pp1-25, CRC press, Boca Raton, FL; 1994.




NAME 

Rajesh C. Miranda, Ph.D. 


rmiranda 





DEGREE 


YEAR(s) 


St. Xavier’s College, Bombay, India B.A. 1982 Psychology 

Bombay University, Bombay, India M.A. 1984 Clinical Psychology 

University of Rochester, Rochester, N.Y. M.A. 1987 Biopsychology 

University of Rochester, Rochester, N.Y. M.S. 1988 Neurobiology 

University of Rochester, Rochester, N.Y. Ph.D. 1989 Biopsychology/Neurobiol. 

Columbia University, Col. Physicians & Surgeons, NY Post-Doctoral 1989-1994 Neurobiology 

Positions and Honors 

1983-1984 St. Xavier’s College, Bombay India, University Grants Commission fellow and teaching 

assistant, Experimental Psychology and Statistics 

1983 Psychaid, Bombay, India, Clinical assistant, psychological testing 

1984-1989 University of Rochester, Depts. of Psychology and Neuroscience: Teaching assistant. 

1989-1992 Columbia University College of Physicians and Surgeons, Center for Reproductive Sciences: 

Post-doctoral research Scientist 

1990-1994 Columbia University College of Physicians and Surgeons, Instructor, Medical Neuroanatomy 

1992-1994 Columbia University College of Physicians and Surgeons, Center for Reproductive Sciences: 

Associate Research Scientist. 

1995-2000 Texas A&M University, Dept. Human Anatomy and Medical Neurobiology, Assistant Professor. 

2000-present Texas A&M, Health Science Center, Associate Professor. 

2005- Texas A&M University, Department of Psychology, Adjunct Professor 

1995-present Member: TAMU Faculties of Neuroscience, Reproductive Biology and Toxicology 

1999-present Member, Center for Environmental and Rural Health, Texas A&M University. 

2002-2003 Ad-hoc reviewer, NIH, ALTX-3 study section. 

2003 Ad-hoc reviewer, NIH, NAL (Neurotoxicology and Alcohol) study section 

2004-2007 Member, NIH, NAL (Neurotoxicology and Alcohol) study section 

2006 Ad. Hoc. member of NIH AA-1 Biomedical Research Review Subcommittee 

Peer-reviewed publications (selected from 32) 

Miranda RC, Wagner J, Kellogg CK, (1989) Early developmental exposure to benzodiazepine ligands: Effects 

on thiobarbituric acid reactive products. Neurochemical Research, 14, 1119-1127. 

Miranda R, Ceckler T, Guillet R, Kellogg CK, (1990) Early developmental exposure to benzodiazepine ligands 

alters brain 31P-NMR spectra in young adult rats. Brain Research, 506, 85-92. 

Miranda R, Ceckler T, Guillet R, Kellogg CK (1990) Aging-related changes in brain metabolism are altered by 

prenatal exposure to diazepam. Neurobiology of Aging, 11, 117-122. 

Miranda RC, Toran-Allerand CD, (1992) Developmental regulation of estrogen receptor mRNA in the rat 

cerebral cortex: a non-isotopic in situ hybridization histochemistry study. Cerebral Cortex, 2, 1-15. 

Toran-Allerand CD, Miranda RC, Bentham W, Sohrabji F, Brown TJ, Hochberg RB, MacLusky NJ (1992) 

Estrogen receptors co-localize with low-affinity nerve growth factor receptors in cholinergic neurons of the 

basal forebrain. Proc. Natl. Acad. Sci. USA. 89, 4668-4672.

Miranda RC, Sohrabji F, Toran-Allerand CD (1993) Neuronal colocalization of mRNAs for the neurotrophins 

and their receptors in the developing central nervous system suggests a potential for autocrine interactions. 

Proc. Natl. Acad. Sci. USA. 90, 6439-6443. 

Miranda RC, Sohrabji F, Toran-Allerand CD (1993) Presumptive estrogen target neurons express mRNAs for 

both the neurotrophins and neurotrophin receptors: a basis for potential developmental interactions of 

estrogen with the neurotrophins. Molecular and Cellular Neurosciences, 4, 510-525. 

Sohrabji F, Miranda RC, Toran-Allerand CD (1994) Estrogen differentially regulates estrogen and nerve growth 

factor receptor mRNAs in adult sensory neurons. Journal of Neuroscience, 14, 459-471. 

Sohrabji F, Greene LA, Miranda RC, Toran-Allerand CD (1994) Reciprocal regulation of estrogen and NGF 

receptors by their ligands in PC12 cells. Journal of Neurobiology 25, 974-988. 

Miranda RC, Sohrabji F, Toran-Allerand CD (1994) Interactions of estrogen with the neurotrophins and their 

receptors during neural development. Hormones and Behavior 28, 367-375. 

Sohrabji F, Miranda RCG, Toran-Allerand CD (1995) Identification of a putative estrogen response element in 

the gene encoding BDNF. Proc. Natl. Acad. Sci. USA 92, 11110-11114. 

Miranda R, Sohrabji F, Singh M, Toran-Allerand CD (1996) Nerve growth factor (NGF) regulation of estrogen 

receptors in explant cultures of the developing forebrain. Journal of Neurobiology 31, 77-87. 

McAlhany Jr. R, West J, Miranda RC (1997) Glial-derived neurotrophic factor rescues calbindin-D28kimmunoreactive 

neurons in alcohol-treated cerebellar explant cultures. Journal of Neurobiology 33, 835-847. 

Cheema ZF, Wade S, Sata M, Walsh K, Sohrabji F, Miranda RC, (1999) Fas/Apo [apoptosis]-1 and associated 

proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of 

NF-kB. Journal of Neuroscience 19(5), 1754-1770. 

McAlhany Jr. RE, West JR, Miranda RC (2000) Glial-derived neurotrophic factor (GDNF) prevents ethanolinduced 

apoptosis and jun kinase phosphorylation. Developmental Brain Research 119, 209-216. 

Craig JC, Bennett GD, Miranda RC, Mackler SA, Finnell RH (2000) Ribonucleotide Reductase subunit R1: A 

gene conferring sensitivity to valproic acid-induced neural tube defects in mice. Teratology 61, 305-313. 

Cheema ZF, West JR, Miranda RC (2000) Ethanol induces Fas/Apo [apoptosis]-1 and cell suicide in the 

developing cerebral cortex. Alcoholism: Clinical and Experimental Research 24 (4), 535-543. 

Anderson R, Harting E, Frey M, Leibowitz JL, Miranda RC (2000) A persistent (DA) strain of Theiler’s murine 

encepahalomyelitis virus (TMEV) induces rapid necrosis as well as delayed apoptosis during the acute 

phase of infection of myelinated mouse cerebellar explant cultures. Brain Research 868 (2) 259-267. 

Tang LS, Wlodarczyk BJ, Santillano DR, Miranda RC, Finnell RH (2004) Developmental consequences of 

abnormal folate transport during murine heart morphogenesis. Birth Defects Research (A) 70(7) 449–458. 

Grau JW, Washburn SN, Hook MA, Ferguson AR, Crown ED, Garcia G, Bolding KA, Miranda RC (2004) 

Uncontrollable stimulation undermines recovery after spinal cord injury. Neurotrauma, 21(12):1795-817. 

Liu GT, Ferguson AR, Crown ED, Bopp AC, Miranda RC, Grau JW (2005) Instrumental learning within the rat 

spinal cord: Localization of the essential neural circuit. Behavioral Neuroscience Apr;119(2):538-47. 

Tang LS, Santillano DR, Miranda RC, Finnell RH (2005) Role of folbp1 in the regional regulation of apoptosis 

and cell proliferation in the developing neural tube and craniofacies. Sem in Med Gene,135C(1):48-58. 

Santillano DR, Kumar LK, Prock TL, Tingling J, Miranda RC (2005) Ethanol induces cell-cycle activity and 

reduces stem cell heterogeneity in cerebral cortical neuroepithelial precursors. Biomed Central: 

Neuroscience 6:59. 

Camarillo C, Kumar LS, Bake S, Sohrabji F, Miranda RC (2006) Ethanol regulates angiogenic cytokines during 

neural development: Evidence from an in vitro model of mitogen-withdrawal induced cerebral cortical 

neuroepithelial differentiation. Alcoholism: Clinical and Experimental Research, 31:324-335.




NAME 

MORA, Miguel 



Adjunct Professor 



DEGREE 


YEAR(s) 

Instituto Politecnico Nacional B.S. 1977 

University of California – Davis M.S. 1985 

University of California – Davis Ph.D. 1990 




2005 US Geological Survey Star Award 

2003 US Geological Survey Star Award 

Memberships 


American Ornithologists Union 

Colonial Watebirds Society 

Cooper Ornithological Society 

SACNAS 

Sigma Xi 

Society of Environmental Toxicology and Chemistry 

Southwestern Association of Naturalists 

The Wildlife Society 

B. SELECTED PEER REVIEWED PUBLICATIONS FROM A TOTAL OF 146: 

Cobos, V.M., M.A. Mora, and G. Escalona. 2006. Plasma cholinesterase inhibition in the clay-colored robin 

(Turdus grayi) exposed to diazinon in a papaya culture in Yucatan, Mexico. Revista de Toxicologia, in 

press. 

Mora, M.A., D. Musquiz, J.W. Bickham, D.S. MacKenzie, M.J. Hooper, J. Szabo, and C.W. Matson. 2006. 

Biomarkers of exposure and effects of environmental contaminants on swallows nesting along the Rio 

Grande, Texas, USA. Environmental Toxicology and Chemistry 25 (6): 000-000. 

Phalen, D.N., M.L. Drew, C. Contreras, K. Roset, and M. Mora. 2005. Naturally occurring secondary nutritional 

hyperparathyroidism in cattle egrets (Bubulcus ibis) from central Texas. Journal of Wildlife Diseases 

41:401-415 

Mora, M.A., T.W. Boutton, and D. Musquiz. 2005. Regional variation and relationships between the 

contaminants DDE and selenium and stable isotopes in swallows nesting along the Rio Grande and one 

reference site, Texas, USA. Isotopes in Environmental and Health Studies 41:69-85. 

Maruya, K.A., K.L. Smalling, and M.A. Mora. 2005. Residues of Toxaphene in insectivorous birds 

(Petrochelidon spp) from the Rio Grande, Texas. Archives of Environmental Contamination and Toxicology 

48:567. 

Mora, M.A. 2004. (Book Review) Fundamentals of Ecotoxicology, Second Edition. Ecological Engineering 

22:213-214.

Mora, M.A. 2003. Heavy metals and metalloids in egg contents and eggshells of passerine birds from Arizona. 

Environmental Pollution 125:393-400. 

Mora, M.A., J. Rourke, S. Sferra, and K. King. 2003. Environmental contaminants in surrogate birds and 

insects inhabiting southwestern willow flycatcher habitat in Arizona. Studies in Avian Biology 26:168-176. 

Mora, M.A., J. Garcia, M.P. Carpio-Obeso, and K. King. 2003. Contaminants without borders: A regional 

assessment of the Colorado River delta ecosystem. P 1125-1134, in D.J. Rapport, W.L. Lasley, D.E. 

Rolston, N.O. Nielsen, C.O. Qualset, and A.B. Damania (eds.) Managing for Healthy Ecosystems, Lewis 

Publishers, Boca Raton, Florida USA. 

Mora, M.A., R. Skiles, B. McKinney, M. Paredes, D. Buckler, D. Papoulias, and D. Klein. 2002. Environmental 

contaminants in prey and tissues of the peregrine falcon in the Big Bend Region, Texas, USA. 

Environmental Pollution 116:169-176. 

Garcia-Hernandez, J., K.A. King, A.L. Velasco, E. Shumilin, M.A. Mora, and E.P. Glenn. 2001. Selenium, 

selected inorganic elements, and organochlorine pesticides in bottom material and biota from the Colorado 

River delta. Journal of Arid Environments 49:65-89. 

Mora, M.A., D. Papoulias, I. Nava, and D. R. Buckler. 2001. Transboundary pollution: A comparative 

assessment of contaminants in fish from four resacas of the Texas, USA-Tamaulipas, Mexico border 

region. Environment International 27:15-20. 

Frank, D.S. M.A. Mora, J.L. Sericano, A.L. Blankenship, K. Kannan, and J.P. Giesy. 2001. Persistent 

organochlorine pollutants in eggs of colonial waterbirds from Galveston Bay and east Texas, USA. 

Environmental Toxicology and Chemistry 20:608-617. 

Wainwright, S.E. M.A. Mora, J.L. Sericano, and P. Thomas. 2001. Chlorinated hydrocarbons and biomarkers of 

exposure in wading birds and fish of the Lower Rio Grande Valley, Texas. Archives of Environmental 

Contamination and Toxicology 40:101-111. 

Mora, M.A., L. L. Laack, M.C. Lee, J. Sericano, R. Presley, P.R. Gardinali, L. R. Gamble, S. Robertson, and D. 

Frank. 2000. Environmental contaminants in blood, hair, and tissues of ocelots from the Lower Rio Grande 

Valley, Texas, 1986-97. Environmental Monitoring and Assessment 64:477-492. 

Mora, M.A. and J.M. Miller. 1998. Foraging flights, reproductive success, and organochlorine contaminants in 

cattle egrets nesting in a residential area of Bryan, Texas. Texas Journal of Science 50:205-214. 

Mora, M.A. and S.E. Wainwright. 1998. DDE, mercury, and selenium in biota, sediments, and water of the Rio 

Grande-Rio Bravo Basin, 1965-1995. Reviews of Environmental Contamination and Toxicology 158:1-52. 

Corson, M.S., M.A. Mora, and W.E. Grant. 1998. Simulating cholinesterase inhibition in birds caused by dietary 

insecticide exposure. Ecological Modelling 105:299-323. 

Mora, M.A., M.C. Lee, J.P. Jenny, T.W. Schultz, J.L. Sericano, and N.J. Clum. 1997. Potential impacts of 

environmental contaminants on recovery of the aplomado falcon in south Texas. Journal of Wildlife 

Management 61:1288-1296. 

Mora, M.A. 1997. Transboundary pollution: persistent organochlorine pesticides in migrant birds of the 

southwestern United States and Mexico. Environmental Toxicology and Chemistry 16:3-11. 

Mora, M.A. 1997. Feeding flights of Cattle Egrets nesting in an agricultural ecosystem. Southwestern Naturalist 

42:52-58. 

Mora, M.A. 1996. Organochlorines and trace elements in four colonial waterbird species nesting in the Lower 

Laguna Madre, Texas. Archives of Environmental Contamination and Toxicology 31:533-537. 

Mora, M.A. 1996. Congener-specific polychlorinated biphenyl patterns in eggs of aquatic birds from the Lower 

Laguna Madre, Texas. Environmental Toxicology and Chemistry 15:1003-1010. 

Clark, D.R. Jr., A. Moreno-Valdez, and M.A. Mora. 1995. Organochlorine residues in bat guano from nine 

Mexican caves 1991. Ecotoxicology 4:258-265. 

Verbrugge, D.A., J.P. Giesy, M.A. Mora, L.L. Williams, R. Rossman, R. A. Moll, and M. Tuchman. 1995. 

Concentrations of dissolved and particulate polychlorinated biphenyls in water from the Saginaw River, 

Michigan. Journal of the Great Lakes Research 21:219-233.

NAME 

Nation, Jack R. 





JNation 


Professor of Psychology 



DEGREE 


YEAR(s) 

University of Central Oklahoma B.A. 1970 Psychology 

University of Oklahoma M.S. 1972 Psychology 

University of Oklahoma Ph.D. 1974 Psychology 


Please refer to the application instructions in order to complete sections A, B, and C of the Biographical 

Sketch. 


1974-1978 Texas A&M University 

Assistant Professor of Psychology 

1979-1984 Texas A&M University 

Associate Professor of Psychology 

1985-present Texas A&M University 

Professor of Psychology 

Awards and Honors 

Distinguished Achievement Award in Teaching, College Level - 1984. Annual award given in the 

College of Liberal Arts, Texas A&M University by Former Students Association. 

Distinguished Achievement Award in Teaching, University Level - 1995. Annual award given by 

Former Students Association of Texas A&M University for outstanding teacher of the University. 

Fellow, College of Liberal Arts Faculty, Texas A&M University - 2000/2002. 

Ralph R. Thomas ’21 Professorship in Liberal Arts - 2001/present. 

University Undergraduate Research Fellow - 2003 

Distinguished Research Award in the College of Liberal Arts -2004 

Murray and Celeste Faskin Chair in Distinguished Teaching-2005/present 

B. Selected peer-reviewed publications (in chronological order).—from 106 

Nation, J.R., Miller, D.K., & Bratton, G.R. (2000). Perinatal lead exposure alters the stimulatory properties of 

cocaine at PND 30 and PND 90 in the rat. Neuropsychopharmacology, 23, 444-454 .

Nation, J.R., Miller, D.K., & Bratton, G.R. (2000). Dietary cadmium exposure alters characteristics of training, 

substitution, and tolerance when morphine is used as a discriminative stimulus. Neurotoxicology, 21, 553-568. 

Miller, D.K., Nation, J.R., Jost, T.E., Schell, J.B., & Bratton, G.R. (2000). Differential effects of adult and 

perinatal lead exposure on morphine-induced locomotor activity in rats. Pharmacology, Biochemistry, and 

Behavior, 67, 281-290. 

Miller, D.K., Nation, J.R., & Bratton, G.R. (2001). The effects of perinatal exposure to lead on the discriminative 

properties of cocaine and related drugs. Psychopharmacology, 158, 165-174. 

Nation, J.R., Cardon, A.L., Heard, H.M., Valles, R., & Bratton, G.R. (2003). Perinatal lead exposure and 

relapse to drug-seeking behavior in the rat: A cocaine reinstatement study. Psychopharmacology, 168, 236- 

243. 

Nation, J.R., Smith, K.R., & Bratton, G.R. (2004). Early developmental lead exposure increases sensitivity to 

cocaine in a self-administration paradigm. Pharmacology, Biochemistry, and Behavior, 77, 127-135. 

Rocha, A., Valles, R., Cardon, A.L., Bratton, G.R., & Nation, J.R. (2004). Self-administration of heroin in rats: 

effects of low-level lead exposure during gestation and lactation. Psychopharmacology, 174, 203-210. 

Cardon, A.L., Rocha, A., Valles, R., Bratton, G.R., & Nation, J.R. (2004). Exposure to cadmium during 

gestation and lactation decreases cocaine self-administration in rats. Neurotoxicology, 25, 869-875. 

Valles, R., Rocha, A., Cardon, A.L., Bratton, G.R., & Nation, J.R. (2005). The effects of the GABA A antagonist 

bicuculline on cocaine self-administration in rats exposed to lead during gestation/lactation. Pharmacology, 

Biochemistry, and Behavior, 80, 611-619. 

Hubbs-Tait, L., Nation, J.R., Krebs, N., & Bellinger, D.C. (2005). Neurotoxicants, micronutrients, and social 

environments: individual and combined effects on children’s development. Psychological Science in the Public 

Interest, 5, 57-121. 

Rocha, A., Valles, R., Cardon, A.L., Bratton, G.R., & Nation, J.R. (2005). Enhanced acquisition of cocaine selfadministration 

in rats developmentally exposed to lead. Neuropsychopharmacology, 30, 2058-2064. 

Valles. R., Rocha, A., & Nation, J.R. (2006). The effects of acquisition training schedule on 

extinction and reinstatement of cocaine self-administration in male rats. Experimental and Clinical 

Psychopharmacology, 14, 245-253.

NAME 






arparrish 



Systems Biology and Translational Medicine 

Texas A&M University System HSC 



DEGREE 


YEAR(s) 


University of Arizona, Tucson AZ B.S. 1994 Biochemistry 

Texas A&M University, College Station TX Ph.D. 1997 Toxicology 

University of Arizona, Tucson, AZ Postdoctoral 1997-1999 Toxicology 



1994-1997 Predoctoral Fellow; Texas A&M University, College of Veterinary Medicine, Department 

of Veterinary Physiology & Pharmacology. 

1997 Postdoctoral Fellow; University of Arizona, College of Medicine, Department of 

Anesthesiology. 

1997-1999 Research Assistant Professor; University of Arizona, College of Medicine, Department of 

Anesthesiology. 

1999-2005 Assistant Professor; Texas A&M University System Health Science Center, College of 

Medicine, Department of Medical Pharmacology & Toxicology. 

2005- Associate Professor; Texas A&M University System Health Science Center, College of 

Medicine, Department of Medical Pharmacology and Toxicology. 

Member, Intercollegiate Faculty of Toxicology. 

Member, Cardiovascular Research Institute. 

Associate Member, Center for Environmental and Rural Health 


2000- Member, American Society of Nephrology 

2002- Editorial Board, Toxicology Letters 

2002- Editorial Board, Cell Biology and Toxicology 

2003,2004 Reviewer, National Cancer Institute Special Emphasis Panel (ZCA1 SRRB-U), Innovative 

Toxicology Models for Drug Evaluation. 

2004- Member, American Society for Pharmacology and Experimental Therapeutics, American 

Physiological Society 

2004- Editorial Board, Journal of Ocular Pharmacology and Therapeutics. 

Honors 

2003 Distinguished Teaching Award, College of Medicine, TAMUS-HSC 

2004 Excellence in Renal Research Award, American Physiology Society Renal Section 

B. Selected peer-reviewed publications (43 peer-reviewed publications)

1. Catania J.M, Parrish A.R., Kirkpatrick D.S., Chitkara M., Bowden G.T., Henderson C.J., Wolf C.R., Clark 

A.J., Brendel K., Fisher R.L. and Gandolfi A.J. (2003) Precision-cut tissue slices from transgenic mice as 

an in vitro toxicology system. Toxicology In Vitro 17:201-205. 

2. Zhang W., Jiang J., Qin C., Thomson L.M., Parrish A.R., Safe S.H. and Simanek E.E. (2003) Triazine 

Dendrimers for Drug Delivery: Evaluation of Solubilization Properties, Activity in Cell Culture, and In Vivo 

Toxicity of a Candidate Vehicle. Supramolecular Chemistry 15:607-616. 

3. Younis, H.S., Parrish, A.R. and Sipes I.G. (2003) The Role of Hepatocellular Oxidative Stress in Kupffer 

Cell Activation During 1,2-Dichlorobenzene Induced Hepatotoxicity. Toxicological Sciences 76:201-211. 

4. Pulido M and Parrish A.R. (2003) Metal-Induced Apoptosis: Mechanisms. Mutation Research 533:227- 

241. 

5. Neerman M.F., Zhang W., Parrish A.R. and Simanek E.E. (2004) In Vitro and In Vivo Evaluation of a 

Melamine Dendrimer as a Vehicle for Drug Delivery. International Journal of Pharmaceutics 281:129-132. 

6. Chen H-T., Neerman M.F., Parrish A.R. and Simanek E.E. (2004) Cytotoxicty, Hemolysis and Acute In 

Vivo Toxicity of Dendrimers Based on Melamine, Candidate Vehicles for Drug Delivery. Journal of the 

American Chemical Society 126:10044-10048. 

7. Neerman M.F., Chen H-T., Parrish A.R. and Simanek E.E. (2004) Reduction of drug toxicity using 

dendrimers based on melamine. Molecular Pharmaceutics 1:390-393. 

8. DuBois D.W., Parrish A.R., Trzeciakowski J.P. and Frye G.D. (2004) Binge ethanol exposure delays 

development of GABAergic miniature postsynaptic currents in septal neurons. Brain Research 

Developmental Brain Research 152:199-212. 

9. Jiang J, Dean D, Burghardt RC and Parrish A.R. (2004) Disruption of Cadherin/Catenin Expression, 

Localization and Interactions During HgCl 2 -Induced Nephrotoxicity. Toxicological Sciences 80:170-182. 

10. Jung K-Y., Dean D., Jiang J., Gaylor S., Griffith W.H., Burghardt R.C., Parrish A.R. (2004) Loss of N- 

cadherin and α-Catenin in the Proximal Tubules of Aging Male Fischer 344 Rats. Mechanisms of Ageing 

and Development 125:445-453. 

11. Covington M.D., Bayless K.J., Burghardt R.C., Davis G.E., Parrish A.R. (2005). Ischemia-Induced 

Cleavage of Cadherins in NRK Cells: Evidence for a Role of Metalloproteinases. American Journal of 

Physiology: Renal Physiology 289:F280-F288. 

12. Parrish A.R., Oliver S., Jenkins D., Ruscio B., Green J.B., Colenda C. (2005). Development of a Short 

Medical School Course on Disaster Response and Bioterrorism. Academic Medicine 80:820-823. 

13. Dubois D.W., Trzeciakowski J.P., Parrish A.R., Frye G.D. (2006) GABAergic miniature postsynaptic 

currents in septal neurons show differential allosteric sensitivity after binge-like ethanol exposure. Brain 

Research, 1089:101-115. 

14. Covington M.D., Burghardt R.C., Parrish A.R. (2006) Ischemia-Induced Cleavage of Cadherins in NRK 

Cells Requires MT1-MMP (MMP-14). American Journal of Physiology: Renal Physiology 290:F43-51.


Provide the following information for the key personnel in the order listed on Form Page 2. 


NAME 

Patricia Victoria Pietrantonio 


Associate Professor Dept. of Entomology, Texas 

A&M University 



DEGREE 


YEAR(s) 


University of Buenos Aires, School of Agronomy (Arg.) Ing.Agronoma 1976-1982 Agronomy/plant breeding 

INTA Fellow-Natl. Inst. of Agric. & Cattle Techn. (Arg.) - 1983-1985 Insect Toxicology 

University of California Riverside, Dept. of Entomology M. S. 1987-1990 Entomology 

University of California Riverside, Dept. of Entomology Ph.D. 1990-1995 Entomology 


Positions and employment 

1981-1982 Teaching assistant. University of Buenos Aires, Depts. of Analytical chemistry and Statistics. 

1986-1987 Researcher permanent staff. National Institute of Agriculture and Cattle Technology (INTA), Arg. 

1990-1995. Research Assistant, Dept. of Entomology, University of California, Riverside 

1994-1995 Teaching assistant. Environmental Toxicology Graduate Laboratory 203. 

1996-2002 Assistant Professor, Dept. of Entomology, Texas A&M University 

2002- present Associate Professor with tenure, Dept. Entomology, Texas A&M University. 

Honors 

1983-1985 INTA Research Fellowship, National Competitive Award. INTA Castelar, Bs.As. Argentina. 

1987-1990 Rotary International Foundation “Freedom from Hunger” Competitive Award for the completion 

of MS in Entomology at UCR. Full tuition and board ($65,000). 

1994 Entomological Society of America “Henry Comstock Award in Entomology for Outstanding 

Graduate Student Achievement”, for the Pacific Branch, ESA. 

2001-2002. DuPont Young Professor Grant 

2004 Executive Vice President and Provost’s Diversity Award for Faculty Individual Achievement, 

TAMU. 

2006 Texas A&M Experiment Station (TAES) Fellow 

B. Selected peer-reviewed publications (in chronological order) Total of 26. 

1. Holmes, S. P., S. K. Frazier, and P. V. Pietrantonio. 2000. Cloning of the 16-kDa V-ATPase proteolipid 

subunit from the red imported fire ant, Solenopsis invicta Buren (Hymenoptera: Formicidae) Arch. Insect 

Biochem. Physiol. 45:109-116. 

2. Pietrantonio, P. V., C. Jagge and C. McDowell. 2001. Cloning and expression analysis of a 5HT7-like 

serotonin receptor cDNA from mosquito Aedes aegypti female excretory and respiratory systems. Insect 

Molecular Biology 10: 357-370. 

3. Pietrantonio, P. V., G. Gibson, S. Nawrocki, F. Carrier and W. P. Knight, Jr. 2000. Insecticide Resistance 

Status, Esterase Activity and Electromorphs from Mosquito Populations of Culex quinquefasciatus Say 

(Diptera: Culicidae), in Houston, Texas. J. Vector Ecology 25: 74-89. 

4. Pietrantonio, P. V., G. Gibson, A. Strey, D. Petzel, and T. K. Hayes. 2000. Characterization of a 

leucokinin binding protein from Aedes aegypti mosquito Malpighian tubule. Insect Biochemistry and 

Molecular Biology 30: 1147-1159.

5. Holmes, S. P., H. He, A. Chen, W. Ivie and P. V. Pietrantonio. 2000. Cloning and developmental 

expression of a lymnokinin-like receptor from the cattle fever tick, Boophilus microplus (Acari: Ixodidae). 

Insect Molecular Biology 9:457-465. 

6. Pietrantonio, P. V., S. P. Holmes, C. Jagge and S. K. Frazier. 2002. Cloning of troponin C and other gene 

fragments from the red imported fire ant Solenopsis invicta Buren (Hymenoptera, Formicidae). 

Southwestern Entomol. Suppl. 25:89-96. 

7. Holmes, S.P., Barhoumi, R., Nachman, R.J. and P.V. Pietrantonio.2003. Functional analysis of a G 

protein-coupled receptor from the southern cattle tick Boophilus microplus (Acari: Ixodidae) identifies it as 

the first arthropod myokinin receptor. Insect Molec. Biol.12: 27-38. 

8. Duchesne, L., Hubert, J.- F., Verbavatz, J. M., Thomas, D., and P.V. Pietrantonio. 2003. Mosquito Aedes 

aegypti (Diptera, Culicidae) aquaporin present in tracheolar cells transports water, not glycerol, and forms 

orthogonal arrays in Xenopus oocyte membranes. Eur. J. Biochem. 270: 422-429. 

9. Bokonon-Ganta, A. H., J. Bernal, P.V. Pietrantonio and M. Setamou. 2003. Survivorship and development 

of fall armyworm, Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae) on conventional and 

transgenic maize cultivars expressing Bacillus thuringiensis Cry9C and Cry1A(b) endotoxins. International 

J. Pest Management 49 (2): 169-175. 

10. Dae-Weon Lee and P. V. Pietrantonio. 2003. In vitro expression and pharmacology of the 5-HT 7 -like 

receptor present in the mosquito Aedes aegypti tracheolar cells and hindgut-associated nerves. Insect 

Mol. Biol. 12: 561-569. 

11. Chen, A., Holmes, S.P. and Pietrantonio, P.V. 2004. Molecular cloning and functional expression of a 

serotonin receptor from the Southern cattle tick, Boophilus microplus (Acari: Ixodidae) .Insect Molec. Biol. 

13:45-54. 

12. Chen, M.-E., Lewis, D.K., Keeley, L.L., and Pietrantonio, P.V. 2004. cDNA cloning and transcriptional 

regulation of the vitellogenin receptor from the imported fire ant, Solenopsis invicta (Hymenoptera: 

Formicidae.). Insect Mol.Biol. 13:195-204. 

13. Pietrantonio, P. V., C. Jagge, S. Taneja-Bageshwar, R. Nachman, and R. Barhoumi. 2004. The mosquito 

Aedes aegypti (L.) leucokinin receptor is a multiligand receptor for the three Aedes kinins. Insect Mol. Biol. 

Insect Mol. Biol. 14: 55-67. 

14. Neupert, S., R. Predel, W.K. Russell, R. Davies, P.V. Pietrantonio and R.J. Nachman. 2005. Identification 

of tick periviscerokinin, the first neurohormone of Ixodidae: single cell analysis by means of MALDI- 

TOF/TOF mass spectrometry. Biochem. Biophys. Res. Comm. 338: 1860-1864. 

15. Pietrantonio, P. V. 2005. Driving forces for target-based insecticide design in the 21 st century. Department 

of Entomology Centennial Celebration. Texas A&M University Press. (Book chapter) 

16. Taneja-Bageshwar, S., A. Strey, P. Zubrzak, P.V. Pietrantonio and R. Nachman. 2005. Structure-activity 

relationships for insect kinins on expressed receptors from a tick (Acari: Ixodidae) and a mosquito 

(Diptera: Culicidae). Pestycydy 3: 55-59 (Pesticides, Poland ISSN: 0208-8703). 

17. Chen, Mei-Er and P.V. Pietrantonio. 2006. The short neuropeptide F-like receptor from the red imported 

fire ant, Solenopsis invicta Buren. Archiv. Insect Biochem. Physiol. 61:195-208. 

18. Chen, Mei-Er, S.P. Holmes, and P.V. Pietrantonio. 2006. The glucose transporter 8 from the fire 

ant Solenopsis invicta Buren. Archiv. Insect Biochem Physiol. 62: 55-72. 

19. Taneja-Bageshwar, S., A. Strey, P. Zubrzak, P.V. Pietrantonio and R. Nachman. 2006. Comparative 

structure-activity analysis of insect kinin core analogs on recombinant kinin receptors from Southern cattle 

tick Boophilus microplus (Acari: Ixodidae) and mosquito Aedes aegypti (Diptera: Culicidae) (for Archiv. 

Insect Biochem. Physiol. Especial issue, proofs available; accepted Dec. 5 2005; two corresponding 

authors).




NAME 




Professor and TAES Faculty Fellow 



DEGREE 


YEAR(s) 


University of Madras, India B.Sc 1983 Botany 

University of Madras, India M.Sc 1985 Industrial Microbiology 

University of Arizona, Tucson Ph.D. 1989 Microbiology & 

I l 

A. Positions and Honors. List in chronological order previous positions, concluding with your present 

position. List any honors. Include present membership on any Federal Government public advisory 

committee. 

1991-1992 Research Scientist, Naval Medical Research Institute, Bethesda, MD 

1998-2000 Associate Professor, Texas Agricultural Experiment Station, El Paso, Texas 

1989-1991 Assistant Research Scientist, Dept. of Soil and Water Science, Univ. of Arizona 

1986-1989 Graduate Teaching Assistant, Dept. Microbiology & Immunology, Univ. of Arizona 

2000-2004 Associate Professor, Poultry Science Department, Texas A&M University 

2000-2005 Associate Director of Research, Institute of Food Science & Engineering 

1992-1998 Assistant Professor, Texas Agricultural Experiment Station, El Paso, Texas 

2004-present Chair, Professional Program in Biotechnology, Texas A&M University 

2003-present Director, National Center for E-Beam Food Research, Texas A&M University 


Pillai, S.D. (Editor) (1998) Microbial Pathogens within Aquifers-Principles &Protocols. Springer-Verlag. 

Makuch-Schulze, D., Bowman, R., Pillai, S.D., and Guan, H. (2003). Field evaluation of the effectiveness of 

surfactant modified zeolites and iron-oxide coated sands for removing viruses and bacteria from 

groundwater. Groundwater Monitoring and Remediation 23:68-75. 

R.C. Bier, S.D. Pillai, T.D. Phillips and R.L. Ziprin (Editors) (2004). Pre-harvest and Post-harvest Food Safety; 

Contemporary Issues and Future Directions. Institute of Food Technologists/Iowa State University Press 

Lu, L*., M.E. Hume, K.L. Sternes, and S.D. Pillai (2004) Genetic diversity of Escherichia coli isolates in 

irrigation water and associated sediments: implications for source tracking. Water Research. 38: 3899- 

3908. 

Sobsey, M.D., M.V. Yates FC, Hsu, G, Lovelace, D. Battigelli, A. Margolin, , S.D. Pillai, and N. Nwachuku 

(2004) Development and evaluation of methods to detect coliphages in large volumes of water. Water Sci 

Technol. 50:211-217. 

Shen, S., W. Berry, S. Jaques, S. Pillai, and J. Zhu. 2004. Differential expression of iodothyronine deiodinase 

type 2 in growth plates of chickens divergently selected for incidence of tibial dyschondroplasia. Animal 

Genetics 35:114-118. 

Lu, L*., M.E. Hume and S.D. Pillai (2004) Autoinducer-2-like compounds and activity on selected produce, 

processed foods, and food additives. Journal of Food Protection 67: 1457-1462.

Pillai, S.D., L. A. Braby, and C. B. Lavergne. (2005). Electron beam technology for food irradiation. International 

Review of Food Science and Technology 96-101 

Corapcioglu, M.Y., J.R. Vogel, C.L. Munster, S.D. Pillai, S. Dowd*, and S.Wang. (2005) Virus transport 

experiments in a sandy aquifer. Water, Air, Soil, Pollution 1-19. 

Lu, L*., M. Hume, and S.D. Pillai (2005) Autoinducer 2-like Activity on Vegetable Produce and its Potential 

Involvement in Bacterial Biofilm Formation on Tomatoes. Foodborne Pathogens and Disease 2: 242-249. 

Duffy, E.A. L. Cisneros-Zevallos, A. Castillo, S. D. Pillai, S. C. Ricke, and G. R. Acuff (2005). Survival of 

Salmonella Transformed to Express Green Fluorescent Protein on Italian Parsley as Affected by 

Processing and Storage. Journal of Food Protection 68: 87-95. 

Lu, L*., M. Hume, and S.D. Pillai (2005) Autoinducer 2-like activity in poultry-associated enteric bacteria in 

response to subtherapeutic antibiotic exposure. Avian Diseases 2005 9(1):74-80. 

E. A. Duffy, L. M. Lucia, J. M. Kells, A. Castillo, S. D. Pillai, and G. R. Acuff (2005). Concentrations of E.coli 

and genetic diversity and antibiotic resistance profiling of Salmonella Isolated from Irrigation Water, 

Packing Shed Equipment, and Fresh Produce in Texas. Journal of Food Protection 68: 70-79. 

Widmer, K.W*., D. Srikumar and S.D. Pillai (2005). Artificial Neural Networks to Accurately Identify 

Cryptosporidium Oocysts and Giardia Cysts Images. Applied and Environmental Microbiology. 71:80-84 

Pillai, S.D. and P. Jesudhasan (2006) Quorum sensing: how bacteria communicate. Food Technology. 60: 42-47.




NAME 




Professor of Chemistry 

Davidson Professor of Science 



DEGREE 


YEAR(s) 


St. Thomas College, St. Paul, MN B.A. 1972 Chemistry 

University of Wisconsin – Madison PhD 1976 Biochemistry 

Pennsylvania State University Postdoctoral 1976-1980 Biophysics 



1980-1986 Assistant Professor of Chemistry, Texas A&M University 

1986-1989 Associate Professor of Chemistry, Texas A&M University 

1989-present Professor of Chemistry and of Biochemistry & Biophysics, Texas A&M University 

1992-1993 Visiting Professor, Enzyme Institute, University of Wisconsin 

2004-present Davidson Professor of Science 

Honors 

1978-1979 NIH National Research Service Award 

1982-1985 NIH New Investigator Research Award 

1985-1990 NIH Research Career Development Award 

1991 Co-Chair, Gordon Research Conference on Enzymes and Metabolic Pathways 

1989-1993 NIH Biomedical Science Study Section – Member 

1995-1999 NIH Biochemistry Study Section – Member 

2003 Chair, Enzyme Mechanisms Conference 

B. Selected Peer-reviewed Publications (selected from 215 peer-reviewed publications). 

F. M. Raushel, “Bacterial Detoxification of Organophosphate Nerve Agents” Current Opinion in Microbiology 5, 288-295 

(2002). 

J. Kim, S. Howell, X. Huang, and F. M. Raushel, “Structural Defects within the Carbamate Tunnel of Carbamoyl 

Phosphate Synthetase” Biochemistry 41, 12575-12581 (2002). 

J. Thoden, X. Huang, F. M. Raushel, and H. M. Holden, “Carbamoyl Phosphate Synthetase: Creation of an Escape Route 

for Ammonia” Journal of Biological Chemistry 277, 39722-39727 (2002). 

J. B. Thoden, J. Kim, F. M. Raushel, and H. M. Holden, Structural and Kinetic Studies of Sugar Binding to Galactose 

Mutarotase from Lactococcus lactis” Journal of Biological Chemistry 277, 45458-45465 (2002). 

J. A. Gerlt and F. M. Raushel, “Evolution of Function in (β/α) 8 -Barrel Enzymes” Current Opinion in Chemical Biology 7, 

252-264 (2003). 

L. Williams, R. Zheng, J. S. Blanchard, and F. M. Raushel, “A Positional Isotope Exchange Analysis of the Pantothenate 

Synthetase Reaction” Biochemistry 42, 5108-5113 (2003). 

J. B. Thoden, R. Marti-Arbona, F. M. Raushel, and H. M. Holden “High Resolution X-ray Structure of Isoaspartyl 

Dipeptidase from Escherichia coli” Biochemistry 42, 4874-4882 (2003). 

J. B. Thoden, J. Kim, F. M. Raushel, and H. M. Holden, “The Catalytic Mechanism of Galactose Mutarotase” Protein 

Science 12, 1051-1059 (2003). 

Y. Li, S. D. Aubert, and F. M. Raushel, “Operational Control of Stereoselectivity During the Enzymatic Hydrolysis of 

Racemic Organophosphorus Compounds” Journal of American Chemical Society 125, 7526-7527 (2003). 

F. M. Raushel, J. B. Thoden, and H. M. Holden, “Enzymes with Molecular Tunnels” Accounts in Chemical Research 36, 

539-548 (2003).

C. M. Hill, W.-S. Li, J. B. Thoden, H. M. Holden, and F. M. Raushel, “Enhanced Degradation of Chemical Warfare Agents 

through Molecular Engineering of the Phosphotriesterase Active Site” Journal of American Chemical Society 125, 

8990-8991 (2003). 

K. T. Lum, H. J. Huebner, Y. Li, T. D. Phillips, and F. M. Raushel, “Organophosphate Nerve Agent Toxicity in Hydra 

attenuata” Chemical Research in Toxicology 16, 953-957 (2003). 

J. B. Garrett, L. S. Mullins, and F. M. Raushel, “Effect of Linker Sequence on the Stability of Circularly Permuted Variants 

of Ribonuclease T1” Bioorganic Chemistry 31, 412-424 (2003). 

F. M. Raushel, “Kinetic Evolution to the Catalytic Core of the Bacterial Phosphotriesterase” in Enzyme Functionality: 

Design, Engineering and Screening (Allan Svendsen, ed. Marcel Dekker, Inc.) pp. 247-259 (2003). 

V. Fresquet, J. B. Thoden, H. M. Holden, and F. M. Raushel, “Kinetic Mechanism of Asparagine Synthetase from Vibrio 

cholerae” Bioorganic Chemistry 32, 63-75 (2004). 

J. Kim and F. M. Raushel, “Access to the Carbamate Tunnel of Carbamoyl Phosphate Synthetase” Archives of 

Biochemistry & Biophysics 425, 33-41 (2004). 

J. Kim and F. M. Raushel, “Perforation of the Tunnel Wall in Carbamoyl Phosphate Synthetase Derails the Passage of 

Ammonia between Sequential Active Sites” Biochemistry 43, 5334-5340 (2004). 

S. D. Aubert, Y. Li, and F. M. Raushel, “Mechanism for the Hydrolysis of Organophosphates by the Bacterial 

Phosphotriesterase” Biochemistry 43, 5707-5715 (2004). 

Y. Li, S. D. Aubert, E. G. Maes, and F. M. Raushel, “Enzymatic Resolution of Chiral Phosphinate Esters” Journal of 

American Chemical Society 126, 8888-8889 (2004). 

M. Park, C. M. Hill, Y. Li, R. K. Hardy, H. Khanna, Y. Khang and F. M. Raushel “Catalytic Properties of the PepQ 

Prolidase from Escherichia coli” Archives of Biochemistry & Biophysics 429, 224-230 (2004). 

V. Fresquet, L. Williams, and F. M. Raushel, “Mechanism of Cobyrinic Acid a,c-Diamide Synthetase from Salmonella 

typhimurium LT2” Biochemistry 43, 10619-10627 (2004). 

J. B. Thoden, X. Huang, J. Kim, F. M. Raushel, and H. M. Holden. “Long Range Allosteric Transitions in Carbamoyl 

Phosphate Synthetase” Protein Science 13, 2398-2405 (2004). 

T. N. Porter, Y. Li, and F. M. Raushel “Mechanism of the Dihydroorotase Reaction” Biochem 43 16285-16292 (2004). 

G. E. Lawson, Y. W. Lee, F. M. Raushel and A. Singh, “Phospholipid-based Catalytic Nanocapsules” Advanced 

Functional Materials 15, 267-272 (2005). 

C. M. Seibert and F. M. Raushel “Structural and Catalytic Diversity within the Amidohydrolase Superfamily” Biochemistry 

44, 6383-6391 (2005). 

R. Marti-Arbona, V. Fresquet, J. B. Thoden, M. L. Davis, H. M. Holden and F. M. Raushel, “Mechanism of the Reaction 

Catalyzed by Isoaspartyl Dipeptidase from Escherichia coli” Biochemistry 44, 7115-7124 (2005). 

S. P. Harvey, J. E. Kolakowski, T.-C. Cheng,Vipin K. Rastogi, L. P. Reiff, J. J. DeFrank, F. M. Raushel, and C. Hill, 

“Stereoselectivity in the Enzymatic Hydrolysis of Cyclosarin (GF)” Enzyme and Microbial Technology 37, 547-555 

(2005). 

C. R. Samples, T. Howard, F. M. Raushel and V. J. DeRose, “Protonation of the Binuclear Metal Center within the Active 

Site of Phosphotriesterase” Biochemistry 44, 11005-11013 (2005). 

E. Ghanem and F. M. Raushel “Detoxification of Organophosphate Nerve Agents by Bacterial Phosphotriesterase” 

Toxicology and Applied Pharmacology 207, 5459-5470 (2005). 

J. J. Irwin, F. M. Raushel, and B. K. Shoichet, “Virtual Screening Against Metalloenzymes for Inhibitors and Substrates” 

Biochemistry 44, 12316-12328 (2005). 

Y. Li and F. M. Raushel, “Inhibitors Designed for the Active Site of Dihydroorotase” Bioorganic Chemistry 33, 470-483 

(2005). 

R. Marti-Arbona, J. B. Thoden, H. M. Holden, and F. M. Raushel, “Functional Significance of Glu-77 and Tyr-137 within 

the Active Site of Isoaspartyl Dipeptidase” Bioorganic Chemistry 33, 448-458 (2005). 

R. Marti-Arbona, C. Xu, S. Steele, A. Weeks, G. F. Kuty, C. M. Seibert, and F. M. Raushel, “Annotating Enzymes of 

Unknown Function: N-Formimino-L-Glutamate Deiminase is a Member of the Amidohydrolase Superfamily” 

Biochemistry 45, 1997-2005 (2006). 

Y. I. Korpan, F. M. Raushel, A. A. Nazarenko, A. P. Soldatkin, N. Jaffrezic-Renault, C. Martelet, “Sensitivity and Specificity 

Improvement of ISFET-based Biosensor for Potato Glycolalkaloids Detection” Journal of Agricultural and Food 

Chemistry 54, 707-712 (2006). 

C. Xu, R. Hall, J. Cummings, and F. M. Raushel, “Tight Binding Inhibitors of N-Acyl Amino Sugar and Amino Acid 

Deacetylases” Journal of the American Chemical Society 128, 4244-4255 (2006). 

Sakai, W. S. Yew, L. Song, D. F. Xiang, C. Xu, F. M. Raushel and J. A. Gerlt, “Evolution of Enzymatic Activities in the 

Enolase Superfamily: N Succinylamino Acid Racemase and a New Pathway for the Irreversible Conversion of D- to 

L-Amino Acids” Biochemistry 45, 4455-4462 (2006). 

L. Williams, T. Nguyen, Y. Li, T. N. Porter, and F. M. Raushel, “Uronate Isomerase: A Nonhydrolytic Member of the 

Amidohydrolase Superfamily with an Ambivalent Requirement for a Divalent Metal Ion” Biochemistry, 45, 7453-7462 

(2006).

NAME 

Reagor, John C. 





Reagor 


Professor of VIBS 



DEGREE 


YEAR(s) 


Agricultural and Mechanical College of Texas MS 1963 Biochemistry and Nutrition 

Texas A&M University Ph.D. 1966 Biochemistry and Nutrition 

A. Positions and Employment 

1965-1969 Assistant Professor, Agricultural Analytical Services and Department of Biochemistry & 

Biophysics, Texas A&M University 

1969-1992 Head, Toxicology, Texas Veterinary Medical Diagnostic Laboratory. Associate Member of the 

Graduate Faculty Physiology and Pharmacology, Texas A&M University 

1992- Head, Toxicology, Texas Veterinary Medical Diagnostic Laboratory. Professor, Department of 

Veterinary Integrated Biosciences, Texas A&M University 

Honors 

1973 Honorary Member Texas Veterinary Medical Association 

1984 Deputy Chancellor’s Distinguished Performance Award 

1986 Award of Special Merit Distinguished Service Award, TVMA 

1995 Award of Special Merit Distinguished Service Award, TVMA 

1998 Regents Fellow 

1998 Faculty Achievement Award, TVMA 

1999 Vice Chancellor’s Award in Excellence 

2002 Special Achievement Award, Texas Sheep and Goat Raisers 

B. Selected peer-reviewed publications 

1. Ray AC, Abbitt B, Cotter SR, Murphy MJ, Reagor JC, Robinson RM, West J, Whitford HW: Bovine abortion 

and death due to ingestion of aflatoxin contaminated peanuts. JAVMA 1986;188:1187-1188. 

2. Casteel SW, Bailey EM Jr, Reagor JC, Rowe LD: Photosensitization – an investigation and review of the 

problem in cattle of South Texas. Vet Hum Tox 1986;28:251. 

3. Casteel SW, Bailey EM Jr, Murphy MJ, Ray AC, Reagor JC: Arsenic poisoning in Texas cattle: the 

implications for your practice. Vet Med 1986;Nov:1045-1049. 

4. Ray AC, Williams HJ, Reagor JC: Pyrrolizidine alkaloids from Senecio longilobus and Senecio glabellus. 

Phytochem 1987;26:2431-2433.

5. Rowe LD, Corrier DE, Reagor JC, Jones LP: Experimentally induced Cassia roemeriana poisoning in cattle 

and goats. Am J Vet Res 1987;48:992-997. 

6. Rowe LD, Norman JO, Corrier DE, Casteel SW, Rector BS, Bailey EM Jr, Schuster JL, Reagor JC: 

Photosensitization in cattle of Southeast Texas: identification of phototoxic activity associated with 

Cooperia pedunculata. Am J Vet Res 1987;48:1658-1661. 

7. Casteel SW, Rowe LD, Bailey EM Jr, Fiske RA, Schwartz WL, Reagor JC, Bridges CW: Experimentally 

induced photosensitization in cattle with Cooperia pedunculata. Vet Hum Tox 1988;30:101-104. 

8. Ray AC, Kyle ALG, Murphy MJ, Reagor JC: Equine cantharidiasis (blister beetles poisoning) – etiology, 

incidence, methodology. Am J Vet Res 1989;50:187-191. 

9. Ray AC, Murphy MJ, DuVall MD, Reagor JC: Determination of brodifacoum and bromadiolone residues in 

rodent and canine liver. Am J Vet Res 1989;50:546-550. 

10. DuVall MD, Murphy MJ, Ray AC, Reagor JC: Case studies of second generation anticoagulant rodenticide 

toxicities in nontarget species. J Vet Diagn Invest 1989;1:66-68. 

11. Murphy MJ, Ray A, Reagor JC, Bailey M: An HPLC method for determination of brodifacoum in serum. Vet 

Hum Tox 1989;31:228-231. 

12. Ray AC, Murphy MJ, Kyle AL, Reagor JC: Etiologic agents, incidence, and improved diagnostic methods 

for cantharidin toxicosis in the equine. Am J Vet Res 1989;50:187-191. 

13. Spainhour CB Jr, Fiske RA, Flory W, Reagor JC: A toxicological investigation of the garden shrub 

Brunfelsia calycina var. floribunda (yesterday-today-and-tomorrow) in three species. J Vet Diagn Invest 

1990;2:3-8. 

14. Ross PF, Rice LG, Reagor JC, Osweiler GO, Wilson TM, Nelson HA, Owens DL, Plattner RD, Harlin KA, 

Richard JL, Colvin BM, Banton MI: Fumonisin B 1 concentrations in feeds from 45 confirmed equine 

leukoencephaolmalacia cases. J Vet Diagn Invest 1991;3:238-241. 

15. Beier RC, Norman JO, Reagor JC, Rees MS, Mundy BP: Isolation of the major component in white 

snakeroot that is toxic after microsomal activation: possible explanation of sporadic toxicity with white 

snakeroot plants and extracts. Natural Toxins 1993;1:286-293. 

16. Barr AC, Abbitt BA, Fiske RA, Jaques JT, Maynard HR, Reagor JC: Reproductive effects of fenoxycarb in 

sheep. J Vet Diagn Invest 1997;9:401-406. 

17. Barr AC, Wigle WL, Flory W, Alldredge BE, Reagor JC: Cantharidin poisoning of emu chicks by ingestion 

of Pyrota insulata. J Vet Diagn Invest 1998;10:77-79. 

18. Garland T, Bailey EM Jr, Reagor JC, Binford E: Probable interaction between Solanum eleagnifolium and 

ivermectin in horses. In: Garland T and Barr AC, eds: Toxic Plants and Other Natural Toxicants. CAB 

International, Wallingford, Oxon, UK, 585pp, 1998.


Give the following information for the key personnel and consultants and collaborators. Begin with the principal 

investigator/program director. Photocopy this page for each person. 

NAME 

Leon H. Russell 


Professor, Tox., Epidemiology and Biostatistics 


INSTITUTION AND LOCATION DEGREE YEAR CONFERRED FIELD OF STUDY 

Univ. Of Missouri, Columbia, MO 

Univ. Of Missouri, Columbia, MO 

Tulane Univ., New Orleans, LA 

Texas A&M Univ., College Station, TX 

B.S. 

D.V.M. 

M.P.H. 

Ph.D. 

1953 

1956 

1958 

1965 

Science 

Vet. Medicine 

Epidemiology 

Vet. Microbiol. 

PROFESSIONAL EXPERIENCE: 

1999-Present Professor, Graduate Faculty of The Texas A&M University System Health Science Center 

Graduate School of Biomedical Sciences, 

1998-Present Professor, Epidemiology and Biostatistics, School of Rural Public Health, Texas A&M Univ. 

1996-Present Professor, Toxicology, Texas A&M University, College Station, TX. 

1969-Present Professor, Veterinary Anatomy & Public Health / Veterinary Integrative Bioscicnces, Texas 

A&M University, College Station, TX. 

1978-Present Professor, Food Science and Technology, Texas A&M University, College Station, TX. 

1977-Present Professor, Medical Microbiology and Immunology, Texas A&M Univ., College Station, TX. 

1976-1979 Professor, Veterinary Microbiology and Parasitology, Texas A&M Univ., College Station, TX. 

1965-1969 Associate Professor, Veterinary Public Health, Texas A&M University, College Station, TX. 

1959-1965 Assistant Professor, Veterinary Public Health, Texas A&M University, College Station, TX. 

HONORS AND AWARDS: 

Phi Tau Sigma, Gamma Sigma Delta, Phi Kappa Phi, Sigma Xi, Phi Zeta 

Texas Veterinary Medical Association Faculty Achievement Award (1969), Research Award (1988) 

Norden Distinguished Teaching Award (1977) 

Former Students Association Faculty Distinguished Achievement Award (1979) 

Former Students Association, College of Veterinary Medicine Teaching Excellence Award (1982) 

Texas Veterinarian Medical Association, President (1984-1985) 

Alumnus of the Year, University of Missouri, College of Veterinary Medicine, Alumni Association (1985) 

American College of Vet. Preventive Medicine-Appreciation Award (1985), Distinguished Diplomate (1989) 

Council for Agriculture and Science, Board of Directors (1987-91) 

TAMU Deputy Chancellor's Award for Excellence in Graduate Teaching (1990) 

American College of Veterinary Preventive Medicine Certificate of Appreciation (1990) 

American Veterinary Epidemiology Society, Honorary Diploma (1990) 

American Veterinary Medical Association, President (1993-1994) 

Association of Military Surgeons of the U.S., James A. McCallam Award (1994) 

Texas Dept. of Health Committee-“Veterinary Response to Chemical in Biological Terrorism in Texas” (1998) 

International HACCP Alliance, Board of Directors (1996-2000) 

Helwig-Jennings Award, American College of Veterinary Preventive Medicine (1998) 

B.G. Russell McNellig Memorial Lecturer, 49 th Intl Military Vet. Med. Symposium, Chiemsee, Germany (1998) 

Distinguished Membership, Texas Veterinary Medical Association (1998) 

XIIth International Veterinary Congress Prize (2000) 

World Veterinary Association Vice-President (2002-2005); World Veterinary Association President (2005-2008) 

Southwest Veterinary Symposium Award for World Leadership in Veterinary Medicine (2005) 

AVMA President’s Award for World Veterinary Leadership (2006)

PUBLICATIONS: 

Szabuniewicz, M., W.L. Schwartz, L.H. Russell, J.D. McCrady, and B.J. Camp. 1972. The experimental 

production and treatment of oleander poisoning in several species of animals. Southwestern Veterinarian 

25:105-114. 

Russell, L.H. 1973. The future role of veterinarians in food safety and his preparation for it. JAVMA 

163:1071-1974. 

Joiner, G.N., L.H. Russell, C.A. Gleiser, and D.E. Bush. 1975. A spontaneous neuropathy of free-ranging 

Japanese Macaques. Lab. An. Sci. 25:232-237. 

Bush, D.E., L.H. Russell, A.I. Flowers, and A.M. Sorenson. 1975. Semen evaluation of Capuchin monkeys 

(Cebus apella). Lab. An. Sci. 25:588-593. 

Russell, L.H. 1978. Chapter: Heavy metals in foods of animal origin. Toxicity of Heavy Metals in the 

Environment. F.W. Oeheme (ed.) Decker, New York. pp. 3-23. 

Davis, D.S., L.H. Russell, L.G. Adams, R.G. Yeager, and R.M. Robinson. 1980. An experimental infection of 

Trypanosoma cruzi in striped skunks (Mephtis mephtis). J. Wildlife Diseases 16:403-406. 

Genigeorgis, C.A., N.D. Heidelbaugh, L.H. Russell, W.F. McCulloch , A.B. Childers. 1980. Educating 

veterinary students in food safety. J. Vet. Med. Educ. 7:71-77. 

Turner, G.V., T.D. Phillips, N.D. Heidelbaugh and L.H. Russell. 1983. High Pressure Liquid Chromatographic 

Determination of Zearalenone in Chicken Tissues. J. Assoc. Off. Anal. Chem. 66(1):102-104. 

Kenyon, E. M., D. N. McMurray, and L. H. Russell, 1984. Isolation of Sporothrix Shenckii from Potting Soil. 

Mycopathologia. 87:128. 

Kenyon, E. M., D. N. McMurray, L. H. Russell, 1984. Isolation of pathogenic Aspergillus Species from 

Commercially Prepared Potting Soil. Mycopathologia. 87:179. 

Russell, L.H., P.D. Teel, and D.E. Bay: 1991. Chapter: Environmental Control of Livestock Disease. CRC 

Handbook of Pest Management in Agriculture. 2nd Ed. Pimentel, D. and Hanson, A. A. CRC Press. Boca 

Raton, FL. 1:623-636. 

Parker, R.W., T.D. Phillips, L.F. Kubena, L.H. Russell and N.D. Heidelbaugh. 1982. Inhibition of pancreatic 

carboxypeptidase A: a possible mechanism of interaction between penicillic acid and ochratoxin A. J. 

Environ. Sci. Health B 17:77-91. 

Turner, G.V., T.D. Phillips, N.D. Heidelbaugh and L.H. Russell. 1982. A high pressure liquid chromatographic 

method for analysis of zearalenone in chicken blood. J. Environ. Sci. Health B 17:297-309. 

McMurray, D.N., L.H. Russell. 1982. Contribution of bats to the maintenance of Histoplasma capsulatum in a 

cave microfocus. Am. J. Trop. Med. Hyg. 31:527-531. 

Russell, L.H.: 1994. Canine Rabies Vaccination. Japan Journal of Veterinary Science. Vol.56 

Russell, L.H. 1994. Symposium on Compounding in Veterinary Medicine. J. Am. Vet. Med. Assoc. 205:194. 

Dykstra, E.A., M.R. Slater, P.D. Teel, L.H. Russell. 1996. Perceptions of veterinary clinics and pest control 

companies regarding tick related problems in Texas cities. AVMA Journal 209:360-365. 

Russell, L.H. 1996. Teaching Food Safety. AVMA Journal 210:1494-95. 

Hanlon, C.A.,J G. Olson, C.J. Clark, & National Working Group on Rabies Control & Prevention. 1999 

Recommendations of a national working group on rabies prevention and control. Article I: Prevention and 

education regarding rabies in human beings. JAVMA 215(9):1276-1280. 

Hanlon, C.A., J. S. Smith, G.R. Anderson, and the National Working Group on Rabies Prevention & 

Control.1999 Recommendations of a national working group on rabies prevention and control.. Article II: 

Laboratory diagnosis of rabies. JAVMA 215 (10):1444-1446. 

Hanlon, C.A., J.E. Childs, V. F. Nettles. and the National Working Group on Rabies Prevention & Control.1999 

Recommendations of a national working group on rabies prevention and control.. Article III: Rabies in 

Wildlife. JAVMA 251 (11): 1612-1618. 

Russell, L.H. 2003. International HACCP Alliance’s “Global HACCP Conference”. In Kechrid, F. et.al., Ed. 

Proceedings of the 27 World veterinary Congress, Tunis, September 27-29, 2002: 329-330. 

Russell, L.H. 2004.The Needs for Public Health Education: Reflections from the 27 th World Veterinary 

Conference. J. Vet. Med. Education 31 (1) 17-22.

NAME 





Schroeder, Friedhelm 





University of Pittsburgh, Pittsburgh, PA B.S. 1970 Chemistry 

Michigan State University, East Lansing, MI Ph.D. 1974 Biochemistry 

Washington Univ Sch of Medicine, St. Louis, MO Postdoctoral 1976 Biological Chemistry 

A. POSITIONS: NSF Grad Fel, Biochem, Michigan State U, East Lansing, MI, 1970-1973; ACS 

Postdoc Fel, Biol. Chem., Washington U Sch Med, St. Louis, MO, 1974-1976; Asst Prof & Assoc 

Prof, Pharmacol., U Missouri Sch Med, Columbia, MO, 1976-87; Visiting Assoc Prof, Biochem, U. 

Virginia, Charlottesville, VA, 1983-84; Assoc Prof & Prof, Pharmacol. U Cincinnati, Cincinnati, OH, 

1987-1994; Prof, Phys & Pharmacol, Texas A&M, College Station, TX, 1994-. 

HONORS: Phillips Med. Chem.; Phi Beta Kappa; NSF Predoc Fel; John Boezi Awd., Mich. State U; Dist. 

Sci. Awd., U. Cincinnati; Dist. Achiev. Awd. in Res.,Texas A&M Univ.; ACS Postdoc. Fel.; ASPET; ASBMB; 

Biophys. Soc.; Am. Oil. Chem. Soc.; Editorial Board Member of Lipids, Prot. Exp. & Purif., Chem. Phys. Lip., 

Cur. in Anal. Chem.; NIH Metab. SS, Member, 1998-2001; Co-Chair, NIH Mouse Metabolic Phenotyping 

Center SS, 2001; Chair, NIH SEP ZRG1 SSS-T (02), 2001; Chair, NIH Fellowship SS, 2002-04; NIH NIGMS 

SEP ZGM1 SIB-2(GG) “Large Scale Collaborative Project Awards”, 2004; Chair, NIH DK SEP ZDK GRB-9(1) 

“Proteomics and Metabolomics in Type 1 Diabetes & Its Complications”; NIH NIBIB SEP ZEB1 OSCR-C (M1) 

“Roadmap Imaging Probes”, 2005; NIH DK ZDK GRB-9 “Mouse phenotyping centers”, 2006; NIH ZRG EMNR- 

E “Nutrition and development”, 2006; Chair, NIH DK ZRG EMNR-B “Pancreatic b-cell development and 

function”, 2006. 

B. SELECTED REPRESENTATIVE PUBLICATIONS (past 5 yrs only; 260 total) 

Gallegos A, Atshaves B, Storey S, McIntosh A, Petrescu A, Schroeder F: SCP-2 expression alters lipid 

distribution and trafficking to the plasma membrane. Biochemistry 40:6493-6506, 2001. 

Schroeder F, Atshaves B, Starodub O, Boedeke A, Smith R, Roths J, Foxworth , Kier A: Expression of 

L-FABP alters growth & differentiation of ES cells. Mol Cell Biochem 219:127-138, 2001. 

Atshaves B, Storey S, McIntosh A, Petrescu A, Lyuksyutova O, Greenberg A, Schroeder F: SCP-2 

expression modulates protein & lipids of lipid droplets J Biol Chem 276:25324-25335, 2001. 

Schroeder F, Gallegos A, Atshaves B, Storey S, McIntosh AL, Petrescu AD, Huang H, Starodub O, 

Chao H, Yang Y, Frolov A, Kier AB: Recent advances in membrane microdomains: Rafts, 

caveolae, & intracellular cholesterol trafficking. Exp. Biol. Med. 226:873-890,2001. 

Petrescu A, Gallegos A, Okamura Y, Strauss J, Schroeder F: StAR binds cholesterol and modulates 

mitochondrial membrane sterol domain dynamics. J.Biol.Chem. 276:36970, 2001. 

Gallegos A, Atshaves B, Storey S, Schoer J, Kier A, Schroeder F: Molecular & fluorescent sterol 

approaches to probe lysosomal membrane lipid dynamics. Chem. Phys. Lip.116:19-38, 2002. 

Atshaves B, Storey S, Petrescu A, Greenberg C, Lyuksyutova O, Smith R, Schroeder F: Expression of FABPs 

inhibits lipid accumulation and alters toxicity in L-cells. Am. J. Physiol. 283: C688-C703, 2002. 

Huang H, Starodub O, McIntosh A, Kier A, Schroeder F: L-FABP targets fatty acids to nucleus: real time 

confocal and multiphoton fluorescence imaging in living cells. J. Biol. Chem. 277:29139-29151, 2002. 

Chao H, Martin G, Russell W, Waghela S, Russell D, Schroeder F, Kier AB: Membrane charge & curvature 

determine interaction with ACBP and fatty acyl CoA targeting. Biochemistry 41:10540-10553, 2002. 

Huang H, Gallegos AM, Zhou M, Ball JM, Schroeder F: Role of sterol carrier protein-2 N-terminal membrane 

binding domain in sterol transfer. Biochemistry 41:12149-12162, 2002. 

Petrescu AD, Hertz R, Bar-Tana J, Schroeder F, Kier AB: Ligand specificity and conformational dependence of 

the hepatic nuclear factor-4α (HNF-4α). J. Biol. Chem. 277:23988-23999, 2002. 

Chao H, Zhou M, McIntosh A, Schroeder F, Kier A: ACBP & cholesterol differentially alter fatty acyl 

CoA utilization by microsomal acyl CoA:cholesterol acyltransferase. J Lip. Res. 44:72-83, 2003. 

Atshaves BP, Storey SM, Schroeder, F: Sterol carrier protein-2/sterol carrier protein-x expression differentially 

alters fatty acid metabolism in L-cell fibroblasts. J. Lipid Res. 44:1751-1762, 2003.

McIntosh A, Gallegos A, Atshaves B, Storey S, Kan D, Schroeder F: Fluorescence & multiphoton imaging 

resolve unique structural form of sterol in membrane of living cells. J. Biol. Chem. 278:6384-6403, 2003. 

Martin G, Danneberg H, Kumar L, Atshaves B, Erol E, Bader M, Schroeder F, Binas B: Decreased liver FA 

binding capacity & altered lipids in mice lacking L-FABP gene. J. Biol. Chem. 278:21429-21438, 2003. 

Martin G, Huang H, Atshaves B, Binas B, Schroeder,F: Ablation of L-FABP gene decreases fatty acyl CoA 

binding capacity & alters fatty acyl CoA pool distribution in mouse liver. Biochem.42:11520-11532, 2003. 

Hertz R, Ben-Haiim N, Petrescu A, Kalderon B, Berman I, Eldad N, Schroeder F, and Bar-Tana J: Rescue of 

MODY-1 by agonist ligands of HNF-4α. J. Biol. Chem. 278:22578-22585, 2003. 

Petrescu AD, Payne HR, Boedecker A, Chao H, Hertz R, Bar-Tana J, Schroeder F, Kier AB: Physical and 

functional interaction of ACBP with HNF-4α. J. Biol. Chem. 278:51813-51824, 2003. 

Atshaves B, Gallegos A, McIntosh A, Kier A, Schroeder F: SCP-2 selectively alters lipid composition and 

cholesterol dynamics of caveolae/lipid raft vs nonraft domains in L-cell plasma membranes. Biochemistry 

42:14583-14598, 2003. 

Atshaves BP, Storey SM, Huang H, Schroeder F: L-FABP expression enhances branched-chain fatty acid 

oxidation. Mol. Cell. Biochem. 259:115-129, 2004. 

Atshaves BP, Payne HR, McIntosh AL, Tichy SE, Russell D, Kier AB, Schroeder F: Sexually dimorphic 

metabolism of branched-chain lipids in C57Bl6/6J mice J. Lip. Res. 45:812-830, 2004. 

Gallegos AM, McIntosh AL, Atshaves BP, Schroeder F: Structure and cholesterol domain dynamics of 

caveolae. Biochem. J. 382:451-461, 2004. 

Zhou M, Parr RD, Petrescu AD, Payne HR, Atshaves BP, Kier AB, Ball JM, Schroeder F: Sterol carrier protein- 

2 directly interacts with caveolin-1 in vitro and in vivo. Biochemistry 43:7288-7306, 2004. 

Atshaves B, McIntosh A, Lyuksyutova O, Zipfel W, Webb W, Schroeder F: L-FABP gene ablation inhibits 

branched-chain fatty acid metabolism in primary hepatocytes. J. Biol. Chem. 279:30954-30965, 2004. 

Atshaves B, McIntosh A, Payne H, Mackie J, Kier A, Schroeder F: Effect of branched-chain fatty acid on lipid 

dynamics in mice lacking the L-FABP gene. Am. J. Physiol. 288:C543-C558, 2005. 

Zhang W, McIntosh A, Xu H, Wu D, Gruninger T, Atshaves B, Liu S, Schroeder, F: Structural analysis of 

sterol distributions in the plasma membrane of living cells. Biochemistry. 44:2864-2884, 2005. 

Petrescu AD, Hertz R, Bar-Tana J, Schroeder F, Kier AB: Role of regulatory F-domain in Hepatocyte Nuclear 

Factor-4α ligand specificity. J. Biol. Chem. 280:16714-16727, 2005. 

Schroeder F, Huang H, Hostetler HA, Petrescu AD, Hertz R, Bar-Tana J, Kier AB: Stability of fatty acyl CoA 

thioester ligands of HNF4α and PPARα. Lipids 40:559-568, 2005. 

Hostetler H, Petrescu A, Kier AB, Schroeder F: PPARα interacts with high affinity and is conformationally 

responsive to endogenous ligands. J. Biol. Chem. 280:18667-18682, 2005. 

Huang H, Atshaves B, Frolov A, Kier A, Schroeder F: Acyl-CoA binding protein expression alters 

liver fatty acyl CoA metabolism. Biochemistry 44:10282-10297, 2005. 

Martin G, Atshaves B, McIntosh A, Mackie J, Kier A, Schroeder F: L-FABP gene ablation alters liver bile acid 

metabolism in male mice. Biochem. J., 391:549-560, 2005. 

Martin G, Atshaves B, McIntosh A, Mackie J, Kier AB, Schroeder F: L-FABP gene ablation induces 

hypercholesterolemia in cholesterol-fed female mice. Am. J. Physiol. 290:G36-G48, 2006. 

Milis D, Moore M, Atshaves B, Schroeder F, Jefferson, J: Sterol carrier protein-2 alters sphingolipid 

metabolism in transfected mouse L-cell fibroblasts. Mol. Cell. Biochem. 283:57-66, 2006. 

Kriska T, Levchenko V, Korytowski W, Atshaves B, Schroeder F, and Girotti A. “Hypersensitivity of SCP-2 

overexpressing hepatoma cells to lethal peroxidative damage induced by an exogenous cholesterol 

hydroperoxide” J. Biol. Chem. 281:23643-23651, 2006. 

Hostetler H, Kier A, Schroeder F. “Very long chain and branched-chain fatty acyl CoAs are high affinity ligands 

for the PPAR” Biochemistry 45:7669-7681, 2006. 

Bandichhor R, Petrescu, A, Vespa A, Kier A, Schroeder F, Burgess K. “Water soluble through bond energy 

transfer cassettes for intracellular imaging” J. Am. Chem. Soc. 128:10688-10689, 2006. 

Bandichhor R, Petrescu A, Vespa A, Kier A, Schroeder F, Burgess K. “Synthesis of new water soluble 

rodamine derivative for protein labeling & intracellular imaging” Bioconj. Chem. 17:1219-1225, 2006. 

Gallegos, AM, Storey, SM, Kier, AB, Schroeder, F, and Ball, JM: Structure and cholesterol dynamics of 

caveolae/raft and non-raft plasma membrane domains. Biochemistry 45:12100-12116, 2006. 

Atshaves B, McIntosh A, Landrock D, Payne H, Mackie J, Maeda N, Ball J, Schroeder F, Kier A. Effect of SCPx 

gene ablation on branched-chain fatty acid metabolism. Am J Physiol, 2006 Oct 26 [Epub ahead of print]. 

Atshaves B, Jefferson J, Kier A, Schroeder F “SCP-2, a new sphingolipid binding protein, alters sphingolipid 

distribution in plasma membrane caveolae/lipid raft domains” J. Biol. Chem. revision pending, 2006.




NAME 

Scott Senseman 



Professor of Weed Science – Pesticide Residue 



DEGREE 


YEAR(s) 


Wilmington College of Ohio B.S. 1986 Agribusiness 

University of Arkansas M.S. 1990 Agronomy – Weed Biology 

University of Arkansas Ph.D. 1995 

Agronomy – Pesticide 

Residue 


Field Technician. April 1986-Aug. 1986. Monsanto Chemical Company, Reynoldsburg, Ohio. 

Graduate Assistant. Aug. 1986-Dec. 1990. Department of Agronomy, Univ. of Arkansas. 

Research Assistant. Jan. 1990-Oct. 1994. Department of Agronomy, Univ. of Arkansas. 

Assistant Professor. Oct. 1994-Sept. 2000. Dept of Soil & Crop Sciences, Texas A&M Univ. 

Associate Professor. Sept. 2000-2005. Department of Soil & Crop Sciences, Texas A&M Univ. 

Professor. Sept. 2005-present. Department of Soil & Crop Sciences, Texas A&M University. 

B. Selected peer-reviewed publications (total of 143) 

Tucker, K.P., G.D. Morgan, S.A. Senseman, T.D. Miller, and P.A. Baumann. 2006. Identification, distribution, 

and control of triasulfuron-resistant Italian ryegrass (Lolium multiflorum) in Central Texas. Weed Technol. 

(Accepted) 

Avila, L.A., J.H. Massey, S.A. Senseman, K.L. Armbrust, S.R. Lancaster, G.N. McCauley, and J.M. Chandler. 

2006. Imazethapyr aqueous photolysis, reaction quantum yield, and hydroxyl radical rate constant. J. 

Agric. Food Chem. (Accepted) 

Cobb, J.M., E.B. Watson, J.D. Mattice, S.A. Senseman, J.A. Dumas, W. Mersie, M.B. Riley, T.L. Potter, and 

T.C. Mueller. 2006. Stability of pesticides on solid-phase extraction disks after incubation at various 

temperatures and time intervals. J. Assoc. Offic. Anal. Chem. (Accepted). 

Sciumbato, A.S., S.A. Senseman, J.B. Ross, T.C. Mueller. 2006. The effect of 2,4-D formulation and 

quinclorac on spray droplet size and deposition. Weed Technol. (Accepted) 

Krutz, L.J., T. Gentry, S.A. Senseman, I. Pepper, and D. Tierney. 2006. Mineralization of atrazine, 

metolachlor, and their respective metabolites in vegetated filter strip and cultivated soil. Pest. Manage. 

Sci. (Accepted) 

Besler, B.A., W.J. Grichar, S.A. Senseman, T.A. Baughman, R.G. Lemon. 2006. Effects of row spacing 

configurations and reduced and full rates of imazapic and diclosulam for control of yellow nutsedge 

(Cyperus esculentus) in peanut (Arachis hypogaea). Weed Technol.(Accepted) 

Riley, M.B., J.A. Dumas, E.E. Gbur, J.H. Massey, J.D. Mattice, W. Mersie, T.C. Mueller, T. Potter, S.A. 

Senseman, and E. Watson. 2005. Pesticide extraction efficiency of two solid-phase disk types after 

shipping. J. Agric. Food Chem. 53:5079-5083. 

Krutz, L.J., S.A. Senseman, and M.A. Matocha. 2005. Reducing herbicide runoff from agricultural fields with 

vegetative filter strips: A review. Weed Sci. 53:353-367. 

Minton, B.W., S.A. Senseman, J.T. Cothren, J.M. Chandler, and J.R. Wells. 2005. Cotton (Gossypium 

hirsutum L.) Response to CGA-362622 applied alone and in combination with selected insecticides. 

Weed Technol. 19:244-250.

Avila, L.A., S.A. Senseman, G.N. McCauley, J.M. Chandler, and J.H. O’Barr. 2005. Effect of flood timing on 

red rice (Oryza spp.) control with imazethapyr applied at different rice stages. Weed Technol. 19:476- 

480. 

Avila, L.A., D.J. Lee, S.A. Senseman, G.N. McCauley, J.M. Chandler, and J. Tom Cothren. 2005. 

Acetolactate synthase (ALS) activity in red rice ecotypes (Oryza spp.) and imidazolinone 

tolerant/resistant rice cultivars (Oryza sativa) in response to imazethapyr. Pest. Manage. Sci. 61:171- 

178. 

Grichar, W.J., B.A. Besler, T.A. Baughman, P.A. Dotray, R.G. Lemon, and S.A. Senseman. 2004. Cotton 

response to imazapic and imazethapyr residues following peanut. Texas J. Agric. Nat. Res. 17:1-8. 

Sciumbato, A.S., J.M. Chandler, S.A. Senseman, R.W. Bovey, and K.L. Smith. 2004. Determining exposure 

to auxin-like herbicides. I. Quantifying injury to cotton (Gossypium hirsutum) and soybeans (Glycine 

max). Weed Technol. 18:1125. 

Sciumbato, A.S., J.M. Chandler, S.A. Senseman, R.W. Bovey, and K.L. Smith. 2004. Determining exposure 

to auxin-like herbicides II. Practical application to quantify volatility. Weed Technol. 18:1135 (Awarded 

Outstanding Paper in Weed Technology for 2004). 

Krutz, L.J., S.A. Senseman, K.J. McInnes, D.W. Hoffman, and D.P. Tierney. 2004. Adsorption-desorption of 

metolachlor, metolachlor oxanilic acid, and metolachlor ethanesulfonic acid in vegetated filter strip and 

cultivated soil. J. Environ. Qual. 33:939-945. 

Viator, R., J.T. Cothren, and S.A. Senseman. 2004. The effect of glyphosate application timings and methods 

on glyphosate-resistant Gossypium hirsutum L. Weed Sci. 52:147-151. 

Lee, D.J., S.A. Senseman, J.H. O’Barr, J.M. Chandler, L.J. Krutz, G.N. McCauley, and Y.I. Kuk. 2004. Soil 

characteristics and water potential effects on plant available clomazone in rice (Oryza sativa). Weed Sci. 

52:310-318. 

Krutz, L.J., S.A. Senseman, M.C. Dozier, D.W. Hoffman, and D.P. Tierney. 2004. Infiltration and adsorption of 

dissolved metolachlor, metolachlor oxanilic acid, and metolachlor ethanesulfonic acid by buffalograss 

[Buchloe dactyloides (Nutt. Engelm)]. Weed Sci. 52:166-171. 

Krutz, L.J., S.A. Senseman, K.J. McInnes, D.A. Zuberer, and D.P. Tierney. 2003. Adsorption and desorption 

of atrazine, desethylatrazine, deisopropylatrazine and hydroxyatrazine in vegetated filter strip and 

cultivated soil. J. Agric. Food Chem. 51:7379-7384. 

Krutz, L.J., S.A. Senseman, M.C. Dozier, D.W. Hoffman, and D.P. Tierney. 2003. Infiltration and adsorption of 

dissolved atrazine and atrazine metabolites in buffalograss filter strips. J. Environ. Qual. 32:2319-2324. 

Viator, R., S.A. Senseman, and J.T. Cothren. 2003. Reproductive Effects of glyphosate-resistant cotton 

(Gossypium hirsutum L.) to glyphosate. Weed Technol. 17:571-575. 

Krutz, L.J., R.L. Haney, and S.A. Senseman. 2003. The effect of glyphosate on atrazine degradation in soil. 

Biol. Fertil. Soils. 38:115-118. 

Senseman, S.A., T.C. Mueller, R.D. Wauchope, C. Clegg, R.W. Young, L.M. Southwick, M.B. Riley, H.A. 

Moye, J.A. Dumas, W. Mersie, J.D. Mattice, and R.B. Leidy. 2003. An interlaboratory comparison of 

extraction efficiency of pesticides from surface and laboratory water. J. Agric. Food Chem. 51:3748- 

3752. 

Cralle, H.T. T.B. Fojtasek, K.H. Carson, J.M. Chandler, T.D. Miller, S.A. Senseman, R.W. Bovey, and M.J. 

Stone. 2003. Wheat and Italian ryegrass (Lolium multiflorum) competition as affected by phosphorous 

nutrition. Weed Sci. 51:425-429. 

Lee, D.J., S.A. Senseman, A.S. Sciumbato, S.C. Jung, and L.J. Krutz. 2003. The effect of titanium dioxide 

alumina beads on the photocatalytic degradation of picloram in water. J. Agric. Food Chem. 51:2659- 

2664.




NAME 

Sherman, Michael 






DEGREE 


YEAR(s) 

University of Massachusetts, Amherst B.A. 1987 Mathematics 

University of North Carolina, Chapel Hill M.S. 1990 Statistics 

University of North Carolina, Chapel Hill Ph.D. 1992 Statistics 



Academic Appointments and Experience 

1999–present Associate Professor, Department of Statistics, Texas A&M University 

1994–1999 Assistant Professor, Department of Statistics, Texas A&M University 

1992–1994 Postdoctoral Fellow, Department of Biostatistics, University of Rochester 

1992–1993 Instructor, Department of Statistics, University of Rochester 

1991–1992 Computer Lab Assistant and Statistical Consultant, School of Nursing, University of North 

Carolina, Chapel Hill. 

1989 Summer Intern, Bureau of Labor Statistics, Department of Labor, Washington, D.C. 

1988–1992 Teaching Assistant and Instructor, Department of Statistics, University of North Carolina at 

Chapel Hill 


2005-present Associate Editor for the Journal of the American Statical Association 

2002 College of Science Distinguished Achievement Award from the Association of Former 

Students at Texas A&M University 

1998-2000 Associate Editor for Biometrics 

B. SELECTED PEER REVIEWED PUBLICATIONS: 

Sherman, M. (1998). Efficiency and robustness in subsampling for dependent data, Journal of Statistical 

Planning and Inference, 75, 133–146. 

Sherman, M. (1998). Databased choice of batch size for simulation analysis, Simulation, 71, 38–47. 

Sherman, M. (1998). Batch variance estimators for the median of simulation output, Operations Research 

Letters, 23, 129-134. 

Sherman, M., and Carlstein, E. (1999). Invited Comment on: Prediction of spatial cumulative distribution 

functions using subsampling by Lahiri, S.N., Kaiser, M.S., Cressie, N., and Hsu, N.J., Journal of the 

American Statistical Association, 94, 86–100. 

Sherman, M. (1999). Inferences for spatial statistics and asymptotic normality, Far East Journal of Statistics, 3, 

275–293. 

Ritvo, G., Sherman, M., Lawrence, A.L., and Samocha, T.M. (2000). Estimation of soil composition in shrimp 

ponds, Journal of Agricultural, Biological, and Environmental Statistics, 5, 115–129. 

Barling, K.S., Sherman, M., Peterson, M.J., Thompson, J.A., McNeill, J.W., Craig, T.M., Adams, G. (2000). 

Spatial associations among density of cattle, abundance of wild canids, and seroprevalence to Neospora 

Caninum, Journal of the American Veterinary Medical Association, 217, 1361-1365.

Politis, D., and Sherman, M. (2001). Moment estimation for statistics from marked point processes, Journal of 

the Royal Statistical Society, Series B, 63, 261–275. 

Sherman, M., and Goldsman, D. (2002). Large sample normality of the batch means variance estimator, 

Operations Research Letters, 319–326. 

Sherman, M. (2002). Invited comment on: Sieve bootstrap with variable length markov chains for stationary 

categorical time series by Buhlmann, Journal of the American Statistical Association, 97, 457–460. 

Phillips, C.D., Munoz, Y., Sherman, M., Rose, M., Spector, W., and Hawes, C. (2003). Effects of Facility 

Characteristics on Departures From Assisted Living: Results From a National Study, Gerontologist, 42, 

690–696. 

Hawes, C., Phillips, C., Holan, S., and Sherman, M. (2004). A National survey of assisted living facilities, 

Gerontologist 43, 875–882. 

Guan, Y., Sherman, M., and J.A. Calvin (2004). A Nonparametric test for isotropy using subsampling, Journal 

of the American Statistical Association, 99, 810–821. 

Phillips, C.D., Holan, S., Sherman, M., Leyk Williams, G., and Hawes, C. (2004). Rurality and nursing home 

quality: results from a national study, American Journal of Public Health, 94, 1717–1722. 

Sherman, M. and Carlstein, E. (2004). Confidence intervals based on estimators with unknown rates of 

convergence, Computational Statistics and Data Analysis, 46, 123–139. 

Phillips, C.D., Holan, S., Sherman, M., Spector, W., and Hawes, C. (2005). Medicare Expenditures for 

Residents in assisted living: data from a national study, Health Services Research, 40, 373–388. 

Hawes, C., Phillips, C.D., Holan, S., Sherman, M., Hutchinson, L. (2005). Assisted living in rural America: 

results from a national study, Journal of Rural Health, 21, 131–139. 

Maity, A. and Sherman, M. (2006). The Two sample t-test with one variance unknown, The American 

Statistician, 60, 163–166. 

Guan, Y., Sherman, M., and Calvin, J.A. (2006). A Test for isotropy for spatial point processes, Biometrics, 62, 

119–125. 

Sherman, M., Apanasovich, T., and Carroll, R.J. (2006). On Estimation in binary autologistic spatial models, 

Journal of Statistical Computation and Simulation, 76, 167–179. 

Guan, Y., Sherman, M., and Calvin, J.A. (2006). On asymptotic properties of the mark variogram estimator of a 

marked point process, Journal of Statistical Planning and Inference (to appear). 

Lim, J., Liu, H. and Sherman, M. (2006). Parameter estimation in the spatial autologistic model with varying 

independent subblocks, under revision for Journal of Statistical Planning and Inference. (in review). 

Guan, Y., Sherman, M. (2006). Efficient model fitting for spatial point processes, under revision for Journal of 

the Royal Statistical Society, Series B. (in review). 

Lim, J., Wang, X. and Sherman, M. (2006). An Adjustment for edge effects using an external field in the Spatial 

Auto-logistic Model, under revision for Computational Statistics and Data Analysis. (in review). 

Li, B., Eriksson, M., Srinivasan, R., Sherman, M. (2006). A Geostatistical method for Texas Nexrad data 

calibration, submitted to Journal of the American Statistical Association. (in review). 

Li, B., Genton, M., and Sherman, M. (2006). On the asymptotic joint distribution of sample space-time 

covariance estimators, submitted to The Annals of Statistics. (in review). 

Phillips, C.D., Shen, R., Chen, M. and Sherman, M. (2006). Evaluating nursing home quality indicators: an 

illustration exploring the impact of facilities on ADL change, submitted to Milibank Quarterly. (in review).




NAME 

Simanek, Eric E. 






DEGREE 


YEAR(s) 

University of Illinois BS 1987-1991 Chemistry 

Harvard University PhD 1991-1996 Chemistry 

Scripps Research Institute Postdoctoral 1996-1998 




1998-2004 Assistant Professor of Chemistry, Texas A&M University 

2004- Associate Professor of Chemistry, Texas A&M University 

Honors 

1991 Carl Shipp Marvel Research Award, University of Illinois 

1991 Outstanding Teaching Award, University of Illinois 

1992 Distinguished Teaching Award, Harvard University 

1994-1995 Eli Lilly Predoctoral Fellowship, 1994-5, Harvard University 

1999 Innovation Award, Research Corporation 

2003-2004 TAMU College of Science Montague-Center for Teaching Excellence Scholar 


Zhang, W.; Nowlan, D.T.III; Thomson, L.M.; Lackowski, W.M.; Simanek, E.E. Orthogonal, Convergent 

Syntheses of Dendrimers Based on Melamine with One or Two Surface Sites for Manipulation. J. Am. 

Chem. Soc. 2001, 123:8914-8922. 

Gonzalez, S.O., Simanek, E.E. Dendrimers. Branching Out of Polymer Chemistry. J. Chem. Ed. 2002, 

79:1222-1231. 

Zhang, W.; Gonzalez, S.O.; Simanek, E.E. Structure-Activity Relationships in Dendrimers Based on 

Triazines: Gelation Depends on Choice of Linking and Surface Groups. Macromolecules 2002, 

35:9015-9021. 

Bell, S.A.; McLean, M.E.; Oh, S.-K.; Tichy, S.E.; Corn, R.M.; Crooks, R.M.; Simanek, E.E. Synthesis and 

Characterization of DNA-Dendrimer Conjugates. Bioconj. Chem. 2003, 14:488-493. 

Zhang, W.; Jiang, J.; Qin, C.; Thomson, L.M.; Parrish, A.R.; Safe,S.H.; Simanek, E.E. Triazine Dendrimers 

for Drug Delivery: Evaluation of Solubilization Properties, Activity in Cell Culture, and In Vivo Toxicity 

of a Candidate Vehicle. Supramol. Chem. 2003, 15:607-615. 

Umali, A.P.; Simanek, E.E. Preparation of Multivalent Dendrimers Through Thiol-disulfide Exchange. Org. 

Lett. 2003, 5:1245-1247. 

Zhang, W.; Tichy, S.E.; Pérez, L.M.; Maria, G.; Lindahl, P.A.; Simanek, E.E. Evaluation of Multivalent 

Dendrimers Based on Melamine: Kinetics of Thiol-Disulfide Exchange Depends on the Structure of the 

Dendrimer. J. Am. Chem. Soc. 2003, 125: 5086-5094.

Acosta, E.J.; Deng, Y.; White, G.N.; Dixon, J.B.; McInnes, K.; Senseman, S.A.; Frantzen, A.S.; Simanek, E.E. 

Dendritic Surfactants Show Evidence for Frustrated Intercalation: A New Organoclay Morphology. Chem. 

Mater. 2003 15:2903-2909. 

Steffensen, M.B.; Simanek, E.E. Chemoselective building blocks for dendrimers from relative reactivity data. 

Org. Lett. 2003, 5:2359-2361. 

Acosta, E.J.; Steffensen, M.B.; Tichy, S.E.; Simanek, E.E. Removal of Atrazine from Water Using Reactive 

Resins. J. Agric. Food Chem. 2004, 52, 545-549. 

Neerman, M.F.; Zhang, W.; Parrish, A.R.; Simanek, E.E. In vivo evaluation of a triazine dendrimer: a potential 

vehicle for drug delivery. Int. J. Pharm. 2004, 281:129-132. 

Acosta, E.; Carr, S.C.; Simanek, E.E.; Shantz. D.F. Engineering Nanospace: Iterative Synthesis of Melaminebased 

Dendrimers on Amine-functionalized SBA-15 Leads to a Stepwise Reduction in Pore Volume. 

Adv. Mater. 2004, 16:985-989. 

Hatfield, S. E.; Harding, K. E.; Hildreth, R. A. Simanek, E. E. Laboratory Chemistry in Context: The Synthesis 

of Triazine Herbicides. J. Chem. Educ. 2004 Submitted. 

Chen, H.-T.; Neerman, M.F.; Parrish, A.R.; Simanek, E.E. Cytotoxicty, Hemolysis and Acute In Vivo Toxicity of 

Dendrimers Based on Melamine, Candidate Vehicles for Drug Delivery. J. Am. Chem. Soc. 2004, 

126:10044-10048. 

Neerman MF; Chen H-T; Parrish AR; Simanek EE. Attenuation of Drug Toxicity Using Dendrimers Based on 

Melamine, Candidate Vehicles for Drug Delivery. Molec. Pharm. 2004, 1:390-393. 

Steffensen, M.B.; Simanek, E.E. Synthesis and Manipulation of Orthogonally Protected Dendrimers: Building 

Blocks for Library Synthesis. Angew. Chem. Int. Ed. 2004, 43:5178-5180. 

Acosta, E. J.; Gonzalez, S.O.; Simanek, E.E. Synthesis, Characterization and Application of Melamine-Based 

Dendrimers Supported on Silica Gel. J. Poly. Sci. A 2004, 143:168-177. 

Simanek, E.E. Dendrimers Based on Melamine: Vehicles for Drug Delivery? A.C.S. Symposium Series. 

2005:156-183. 

Hollink, E.; Tichy, S.E.; Simanek, E.E. Piperidine-Functionalized Supports as a Method to Sequester Atrazine 

from Solution. Ind. Eng. Chem. Res. 2005, 44:1634-1639. 

Gonzalez, S.O.; Furyk, S.; Li, C.; Tichy, S. E.; Bergbreiter, D. E.; Simanek, E. E. Latent Solid-Phase Extraction 

Using Thermoresponsive Soluble Polymers. J. Poly. Sci. A. 2004, 42:6309-6317. 

Neerman, M.F.; Umali, A. P.; Chen, H.–T.; Waghela, S. D.; Parrish, A. R.; Simanek, E. E. Biological 

Evaluations of Dendrimers Based on Melamine. J. Drug Del. Sci. Tech. 2005, 15:31-40. 

Hollink, E.M.; Bergbreiter, D.E.; Simanek, E.E. Strategies for protecting and manipulating triazine derivatives. 

Tetrahedron Lett. 2005, 46:2005-2008. 

Ford, D.M.; Simanek, E.E.; Shantz, D.F. Engineering Nanospace: Ordered Mesoporous Silicas as Model 

Substrates for Building Complex Hybrid Materials. Nanotechnology. 2005, 16:458-475. 

Bergbreiter, D.E.; Simanek, E.E.; Owsik, I. New Synthetic Methods for the Formation of Basic, Polyvalent, 

Hyperbranched Grafts. J. Poly. Sci. A 2005, 43:4654-4665. 

Simanek, E. E. "Magic" May Grow on Trees... Molec. Pharm. 2005, 2:251-252. 

Lim, J.; Simanek, E. E. Toward the Next-Generation Drug Delivery Vehicle: Synthesis of a Dendrimer with 

Four Orthogonally Reactive Groups. Molec. Pharm. 2005, 2:273-277. 

Steffensen, M.B. Hollink, E.; Bauer, M., Simanek, E.E. The History of Triazine Dendrimers. J. Poly Sci. 2006, 

In press. 

Hollink, E.; Simanek, E.E. A Divergent Route to Diversity. Org. Lett. 2006, 8:2293-2295.




NAME 

Spencer, Thomas E. 


TSPENCER68 


Associate Professor of Reproductive Biology and 

Physiological Genomics 



DEGREE 


YEAR(s) 


Auburn University, Auburn, AL B.S. 1989 Animal Science 

Auburn University, Auburn, AL M.S. 1992 Animal Science 

Texas A&M University, College Station, TX Ph.D. 1995 Reproductive Biology 

Baylor College of Medicine, Houston, TX Postdoctoral 1995-1997 


Molecular and Cell 

Biology 


1995-1997 NIH Postdoctoral Fellow. Department of Cell Biology, Baylor College of Medicine, Houston, TX. 

Supervisor: Drs. Bert W. O’Malley and Ming-Jer Tsai. 

1997-2001 Research Assistant Professor. Center for Animal Biotechnology and Genomics, Albert B. Alkek 

Institute of Biosciences and Technology, Texas A&M University System Health Science Center, 

College Station. 

2001-2005 Assistant Professor of Reproductive Biology and Physiological Genomics. Department of Animal 

Science, Texas A&M University, College Station. 

2005- Associate Professor. Department of Animal Science, Texas A&M University, College Station. 

Co-Director, Environment and Reproduction Research Core, NIEHS Center for Environmental 

and Rural Health. 


Member: American Association for the Advancement of Science; American Society of Animal Science; 

Endocrine Society; NIH Center for Functional Glycomics; Society for Reproduction and Fertility; Society for 

the Study of Reproduction; Sigma Xi; Texas Women’s Reproductive Health Consortium. 

Scientific Review: American Journal of Reproductive Immunology (Editorial Board, 2005-2008); Biology of 

Reproduction (Associate Editor, 2005-; Editorial Board, 2001-2005); Reproduction (Editorial Board, 2004- 

2007). 

Grant Review: Binational Agricultural Research and Development (BARD) Fund; Genome Canada; 

Horserace Betting Levy Board; Medical Research Council, United Kingdom; NASA; NIH (Ad hoc NICHD 

CMIR and PN Study Sections; U54 Study Section); NSF; USDA-NRI; The Lalor Foundation; The Wellcome 

Trust. 

Honors 

American Society of Animal Science (ASAS) Young Animal Scientist Award-Research (2003); Society for the 

Study of Reproduction (SSR) New Investigator Award (2004); Sigma Xi Young Investigator Award (2005); 

Texas A&M University Vice Chancellor’s Award in Excellence for Individual Research and for Team Research 

(2006); Vice Chair, Gordon Research Conference on Reproductive Tract Biology (2006); Chair, Gordon 

Research Conference on Reproductive Systems Biology (2008).


(Publications selected from 105 peer-reviewed papers and 40 invited reviews and book chapters) 

1. Dunlap K, Palmarini MA, Adelson DL, Spencer TE. Sheep endogenous betaretroviruses (enJSRVs) and 

the hyaluronidase 2 (HYAL2) receptor in the ovine uterus and conceptus. Biol Reprod 2005; 73:271-279. 

2. Fu WJ, Haynes TE, Kohli R, Hu J, Shi W, Spencer TE, Carroll RJ, Meininger CJ, Wu G. Dietary L-arginine 

supplementation reduces fat mass in zucker diabetic fatty rats. J Nutr 2005; 135:714-721. 

3. Gray CA, Dunlap KA, Burghardt RC, Spencer TE. Galectin-15 in ovine uteroplacental tissues. 

Reproduction 2005; 130:231-240. 

4. Hayashi K, Carpenter KD, Welsh TH Jr, Burghardt RC, Spicer LJ, Spencer TE. The IGF system in the 

developing neonatal ovine uterus. Reproduction 2005; 129:1-12. 

5. Joyce MM, White FJ, Burghardt RC, Muniz JJ, Spencer TE, Bazer FW, Johnson GA. Interferon 

stimulated gene 15 (ISG15) conjugates to endometrial cytosolic proteins and is expressed at the uterineplacental 

interface throughout pregnancy in sheep. Endocrinology 2005; 146:675-684. 

6. Hayashi K, Spencer TE. Estrogen disruption of neonatal ovine uterine development: effects on gene 

expression assessed by suppression subtraction hybridization. Biol Reprod 2005; 73:752-760. 

7. Hu J, Spencer TE. Carbonic anhydrases regulate endometrial gland development in the neonatal uterus. 

Biol Reprod 2005; 73:131-138. 

8. Padua MB, Tekin S, Spencer TE, Hansen PJ. Actions of progesterone on uterine immunosuppression 

and endometrial gland development in the uterine gland knockout (UGKO) ewe. Mol Reprod Dev 2005; 

71:347-257. 

9. Song G, Spencer TE, Bazer FW. Cathepsins in the ovine uterus: regulation by pregnancy, progesterone 

and interferon tau. Endocrinology 2005; 146:4825-4833. 

10. Wu G, Bazer FW, Hu J, Johnson GA, Spencer TE. Polyamine synthesis from proline in the developing 

porcine placenta. Biol Reprod 2005; 72:842-850. 

11. Ashworth MD, Ross JW, Hu J, White FJ, Stein DR, DeSilva U, Johnson GA, Spencer TE, Geisert RD. 

Porcine endometrial prostaglandin synthase expression during the estrous cycle, early pregnancy and 

following endocrine disruption of pregnancy. Biol Reprod 2006; 74:1007-1015. 

12. Fleming JGW, Spencer TE, Safe SH, Bazer FW. Estrogen regulates transcription of the ovine oxytocin 

receptor gene through GC-rich SP1 promoter elements. Endocrinology 2006; 147:899-911. 

13. Fu WJ, Hu J, Spencer T, Carroll R, Wu G. Statistical models in assessing fold change of gene expression 

in real-time RT-PCR experiments. Computational Biology and Chemistry 2006; 30:21-26. 

14. Gray CA, Abbey CA, Beremand PD, Choi Y, Farmer JL, Adelson DL, Thomas TL, Bazer FW, Spencer TE. 

Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the 

ovine uterus. Biol Reprod 2006; 74:383-394. 

15. Hayashi K, Spencer TE. Wnt pathways in the neonatal ovine uterus: potential specification of endometrial 

gland morphogenesis by SFRP2. Biol Reprod 2006; 74:721-733. 

16. Song G, Wagner GF, Bazer FW, Spencer TE. Stanniocalcin (STC) in the endometrial glands of the ovine 

uterus: regulation by progesterone and placental hormones. Biol Reprod 2006; 74:913-922. 

17. Song G, Spencer TE, Bazer FW. Progesterone and interferon tau regulate cystatin C (CST3) in the 

endometrium. Endocrinology 2006; 147:3478-3483. 

18. Satterfield MC, Bazer FW, Spencer TE. Progesterone regulation of pre-implantation conceptus growth 

and galectin 15 (LGALS15) in the ovine uterus. Biol Reprod 2006; 75:289-296. 

19. Dunlap KA, Palmarini MA, Spencer TE. Ovine endogenous betaretroviruses (enJSRVs) and placental 

morphogenesis. Trophoblast Res 2006; 27 Suppl:135-40. 

20. Dunlap KA, Palmarini M, Varela M, Burghardt RC, Hayashi K, Farmer JL, Spencer TE. Endogenous 

retroviruses regulate peri-implantation placental growth and differentiation. Proc Natl Acad Sci USA 2006; 

103:14390-14395.


NAME 

Spiegelman, Clifford H. 



Professor of Statistics 



DEGREE 


YEAR(s) 


SUNY, Buffalo, New York B.A. 1970 

Economics, Math, 

Statistics 

Northwestern University, Evanston, IL M.S. 1973 Managerial Economics 

Northwestern University, Evanston, IL Ph.D. 1976 


Statistics/Applied 

Mathematics 


2005- Adjunct Investigator, Biostatistics Branch, Division of Cancer Epidemiology and Genetics 

National Cancer Institute 

2004- Senior Research Scientist TTI 

1990- Professor, Department of Statistics, Texas A&M University 

1993-96 Adjunct Professor of Chemistry, Lamar University 

1987-90 Associate Professor, Department of Statistics, Texas A&M University 

1978-87 Statistical Engineering Division, National Bureau of Standards, Gaithersburg, MD 

1986 Visiting Faculty Member, Dept. of Math Sciences, Johns Hopkins University 

1982-83 Visiting Faculty Member, Department of Mathematics, Northwestern University 

1976-77 Assistant Professor of Statistics, Florida State University 


Member of the American Statistical Association 

Member of the Institute of Mathematical Statistics 

Ordinary Member, International Statistical Institute 

Member of the Bernoulli Society 

Member of the American Chemical Society 

Member Society for Applied Spectroscopy 

Member International Environmetrics Society 

Consultant (title pending) to the Proteomics Program at the National Cancer Institute 

National Committees 

2006 Member Editorial Advisory Board for the Journal of Proteome Research 

2003 NRC committee for the FBI Bullet Lead Analysis 

2002-03 Head and co-organizer of Transportation Statistics interest group within the ASA Editorial 

1994-96 Member, ASA Committee on International Standards, Head of Committee, 1996 

1994 Member, Federal Advisory Committee ACT Committee to EPA. 

1991-92 Past President, South East Texas Chapter of the American Statistical Association 

1990-91 President, South East Texas Chapter of the American Statistical Association. 

1988-94 Associate Editor of Journal of the American Statistical Association 

1988 Acting Editor of Journal of the American Statistical Association, Theory Methods Section, July 

1988 Invited Contributing Scholar for Chemtracts – Analytical and Physical Chemistry 

1987-91 Head ASA Committee on Statistics in Chemistry

1987-91 Executive board ASA Section on Physical and Engineering and Sciences 

1987-91 Head of Conference on Mathematics in Chemistry 

1987 International Chemometric Society Representative to the ASA 

1986 -99 Editorial Board The Journal of Chemometrics 

1985 Guest Editor of the NBS Journal of Research, November-December 1985 issue containing the 

Chemometrics Research Conference Proceedings. 

1985 Editor of Chemometrics and Intelligent Laboratory Systems 

Honors 

2005 ASA invited Chance Lecturer 

2006 Statistics and Chemistry Award for best paper, joint award 

2007 Distinguished Achievement Award, ASA Section on the Environment 

2008 Fellow, American Statistical Association 

2009 W.J. Youden Award given by the American Statistical Association for the best paper on 

Interlaboratory comparisons. 

1990 Fellow, Institute of Mathematical Statistics 


(Publications selected from over 90 peer-reviewed publications) 

1979 Spiegelman, C. On Estimating the Slope of a Straight Line when both Variables are Subject to Error. 

Annals of Statistics, Vol. 7, 201-206. 

1998 Spiegelman, C., Speed, F. M., Evaluating black boxes: An Ad-hoc Method for Assessing 

Nonparametric and Nonlinear Curve-fitting Estimators, Communications in Statistics-Simulation and 

Computation., 27(3), 699-710. 

1998 Spiegelman, C., McShane, M. J., Goetz, M. J., Motamedi, M., Yue, Q. L., and Cote', G. L., Theoretical 

Justification of Wavelength Selection in PLS Calibration: Development of a New Algorithm, Anal. Chem. 

70, 35-44. 

1999 Spiegelman, C., McShane, M. J., Cameron, B. D., Coté, G. L. and Motamedi, M., A Novel Peakhopping 

Stepwise Feature Selected Method with Application to Raman Spectroscopy, Analytical 

Chemica Acta., 388, 251-264. 

2001 Rilett, L. R. and Spiegelman, C. A Discussion of "Statistically Based Validation of Computer Simulation 

Models in Traffic Operation sand management" by Sacks, Rouphail, Park, and Thakuriah, Journal of 

Transportation and Statistics. 

2002 Spiegelman, C., Wikander, J., O’Neal, P., and Coté, G. L., A Simple Method for Linearizing Nonlinear 

Spectra for Calibration, Chemometrics and Intelligent Laboratory Systems, 60, p 197-210. 

2003 Hamada, M., Pohl, A., and Wendelberger, J. and Spiegelman, C. A Bayesian Approach to Calibration 

Intervals and Properly Calibrated Tolerance Intervals, Journal of Quality Technology, Vol. 35, No. 2. 

2003 Spiegelman, C. and Park, Eun Sug. Nearly nonparametric multivariate density estimates that 

incorporate marginal parametric density information, American Statistician, 57, 183-188. 

2004 Gajewski, B.J., and Spiegelman, C.H., “Correspondence Estimation of the Source Profiles in Receptor 

Modeling,” Environmetrics, 15, 613-634. 

2005 Spiegelman, C.H., Lee, Sang-Joon, Conny, Joseph M., Ruymgaart, Frits H., “Some Aspects of 

Multivariate Calibration with Incomplete Designs,” Chemometrics and Intelligent Laboratory Systems 

77, 161-172. 

2006 Spiegelman, C.H. & Kafadar, K. (2006). Data Integrity and the Scientific Method: The Case of Bullet 

Lead Data as Forensic Evidence, Chance (19)2, 17-25. 

2006 Schechtman, E., & Spiegelman, C. (2006). Mitigating the Effect of Measurement Errors in Quantile 

Estimation. Statistics and Probability Letters. To appear.

Principal Investigator/Program Director (Last, First, Middle): 




NAME 





DEGREE 


YEAR(s) 


PHS 398/2590 (Rev. 09/04) Page Biographical Sketch Format Page

Principal Investigator/Program Director (Last, First, Middle): 

PHS 398/2590 (Rev. 09/04) Page Continuation Format Page


Provide the following information for the key personnel in the order listed for Form Page 2. 

Follow the sample format for each person. DO NOT EXCEED FOUR PAGES. 

NAME George Stoica POSITION TITLE Professor 



DEGREE 


YEAR(s) 


Yassv, Romania 

Ohio State University 

Michigan State University 

DVM 

MS 

PhD 

1966 

1982 

1984 


EMPLOYMENT and HONORS 

1984-1990 Assistant Professor, Department of Veterinary Pathobiology, Texas A&M University 

1990-1996 Associate Professor, Department of Veterinary Pathobiology, Texas A&M University. 

1990-1996 Phi Beta Delta, Soc. for International Scholars 

1996-present Full Professor, Department of Veterinary Pathobiology, Texas A&M University 

1993-present Adjunct Professor, University of Texas M.D. Anderson Cancer Center, Department of 

Carcinogenesis, Science Park-Research Division 

1982-present Phi Zeta 

1990-present PHI BETA DELTA. Society of International Scholars 

1997 Developmental Leave (May to November), IARC-Lyon, France 

1998 President of Phi Zeta Honor Society of Veterinary Medicine 

2001 Elected Active Member of Texas A&M University Senate 

2001 Honorary Member of the University of Yassy-Romania 

Ad hoc grant/manuscript reviewer for: 

Molecular Carcinogenesis 

Journal of Veterinary Medical Association 

Journal of Clinical & Experimental Metastases 



American Journal of Physiology: Heart and Circulatory Physiology 

United State Department of Agriculture 

NIH Consultant and Reviewer 

Selected peer-reviewed publications (in chronological order; published or accepted only). 

Guyer CL., Stoica G., Womack J., Storts RW., Deer JN., and Abbott LC. A line of Berlin Druckrey rats 

proposed as a new model for human hereditary ataxia. (2002), In Vivo 16:255-264. 

X. Wang, Y. Pang, G. Ku, X. Xie, G. Stoica, and L. Wang, "Non-invasive laser-induced photoacoustic 

tomography for structural and functional imaging of the brain in vivo," Nature Biotechnology 21 (7), 803– 

806 (July 2003). 

S. Jiao, W. Yu, G. Stoica, and L. Wang, "Optical-fiber-based Mueller optical coherence tomography," Optics 

Letters 28 (14): 1206–1208 (July 2003). 

X. Wang, Y. Pang, G. Ku, G. Stoica, and L. Wang, "Three-dimensional laser-induced photoacoustic 

tomography of the mouse brain with the skin and skull intact," Optics Letters 28:1739-1741 (2003). 

Ku G, Wang X, Xie X, Stoica G, Wang LV. Imaging of tumor angiogenesis in rat brains in vivo by photoacoustic 

tomography. Appl Opt. 2005 Feb 10;44(5):770-5. 

Maslov K, Stoica G, Wang LV. In vivo dark-field reflection-mode photoacoustic microscopy. Opt Lett. 2005 Mar 

15;30(6):625-7.

Kim HT, Qiang W, Liu N, Scofield VL, Wong PK, Stoica G. Up-regulation of astrocyte cyclooxygenase-2, 

CCAAT/enhancer-binding protein-homology protein, glucose-related protein 78, eukaryotic initiation factor 

2 alpha, and c-Jun N-terminal kinase by a neurovirulent murine retrovirus. J Neurovirol. 2005 

Apr;11(2):166-79. 

Mendes O, Kim HT, Stoica G. Expression of MMP2, MMP9 and MMP3 in breast cancer brain metastasis in a 

rat model. Clin Exp Metastasis. 2005;22(3):237-46. 

Jiao S, Todorovic M, Stoica G, Wang LV. Fiber-based polarization-sensitive Mueller matrix optical coherence 

tomography with continuous source polarization modulation. Appl Opt. 2005 Sep 10;44(26):5463-7. 

Liu N, Stoica G, Yan M, Scofield VL, Qiang W, Lynn WS, Wong PK. ATM deficiency induces oxidative stress 

and endoplasmic reticulum stress in astrocytes. Lab Invest. 2005 Dec;85(12):1471-80. 

Li ML, Zhang HE, Maslov K, Stoica G, Wang LV. Improved in vivo photoacoustic microscopy based on a 

virtual-detector concept. Opt Lett. 2006 Feb 15;31(4):474-6. 

Qiang W, Kuang X, Liu J, Liu N, Scofield VL, Reid AJ, Jiang Y, Stoica G, Lynn WS, Wong PK.Astrocytes 

survive chronic infection and cytopathic effects of the ts1 mutant of the retrovirus Moloney murine leukemia 

virus by upregulation of antioxidant defenses. J Virol. 2006 Apr;80(7):3273-84. 

Gaudio E, Barbaro B, Alvaro D, Glaser S, Francis H, Ueno Y, Meininger CJ, Franchitto A, Onori P, Marzioni M, 

Taffetani S, Fava G, Stoica G, Venter J, Reichenbach R, De Morrow S, Summers R, Alpini G. Vascular 

endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism. 

Gastroenterology. 2006 Apr;130(4):1270-82. 

Oh JT, Li ML, Zhang HF, Maslov K, Stoica G, Wang LV. Three-dimensional imaging of skin melanoma in vivo 

by dual-wavelength photoacoustic microscopy. J Biomed Opt. 2006 May-Jun;11(3):34032. 

Wang X, Xie X, Ku G, Wang LV, Stoica G. Noninvasive imaging of hemoglobin concentration and oxygenation 

in the rat brain using high-resolution photoacoustic tomography. J Biomed Opt. 2006 Mar- 

Apr;11(2):024015. 

Zhang HF, Maslov K, Stoica G, Wang LV. Functional photoacoustic microscopy for high-resolution and 

noninvasive in vivo imaging. Nat Biotechnol. 2006 Jul;24(7):848-51. Epub 2006 Jun 25. 

Song KH, Stoica G, Wang LV. In vivo three-dimensional photoacoustic tomography of a whole mouse head. 

Opt Lett. 2006 Aug 15;31(16):2453-5. 

Zhang HF, Maslov K, Stoica G, Wang LV. Imaging acute thermal burns by photoacoustic microscopy. J 

Biomed Opt. 2006 Sep-Oct;11(5):054033. 

Lungu GF, Li ML, Xie X, Wang LV, Stoica G. In vivo imaging and characterization of hypoxia-induced 

neovascularization and tumor invasion. Int J Oncol. 2007 Jan;30(1):45-54. 

Wang L, Wang X, Ku G, Xie X, Stoica G. High-resolution ultrasound-aided biophotonic imaging. Conf Proc 

IEEE Eng Med Biol Soc. 2004;7:5307-10. 

Wang L, Xie X, Oh JT, Li ML, Ku G, Ke S, Similache S, Li C, Stoica G. Combined photoacoustic and molecular 

fluorescence imaging in vivo. Conf Proc IEEE Eng Med Biol Soc. 2005;1:190-2. 

Sivaramakrishnan M, Maslov K, Zhang HF, Stoica G, Wang LV. Limitations of quantitative photoacoustic 

measurements of blood oxygenation in small vessels. Phys Med Biol. 2007 Mar 7;52(5):1349-61. Epub 

2007 Feb 8.




NAME 



JAThompson 


Associate Professor, Toxicology and Large Animal 

Clinical Science 



DEGREE 


YEAR(s) 


University of Guelph DVM 1982 Veterinary Medicine 

University of Guelph DVSc 1991 Population Medicine 

ADVANCED CLINICAL QUALIFICATIONS 

Diplomate, American College of Theriogenology (Veterinary Reproduction) 

Diplomate, American College of Preventive Veterinary Medicine (Epidemiology Specialty) 

POST-DOCTORAL TRAINING IN HIERARCHAL AND SPATIAL MODELING 

Hierarchical Modeling and Analysis for Spatial Data, October 2004, A Bayesian Statistical Short Course 

offered by the American Statistical Association, Alexandria, VA. Instructor: Brad Carlin 

Hierarchical Bayes Methods and Software for Data Analysis, October 2002, A Statistical Short Course 

offered by the American Statistical Association, Alexandria, VA. Instructor: Brad Carlin 

S-PLUS for SAS Users, February 2001, Statistical Short Course offered by Insightful Corp. Washington, 

DC 

Spatial Statistics, August-December 2000, A graduate-level course audited during sabbatical leave in 

the Department of Statistics Texas A&M University 

General Linear Models, August-December 2000, A graduate-level course audited during sabbatical 

leave in the Department of Statistics Texas A&M University 

Geographical Information Systems, August-December 2000, A graduate-level course audited during 

sabbatical leave in the Department of Statistics Texas A&M University 

Linear Algebra, May-June 2000, An undergraduate-level course audited during sabbatical leave in the 

Department of Statistics Texas A&M University 

S+ Spatial Stats and S-PLUS for ARCVIEW GIS, December 2000, Statistical Short Course offered by 

Insightful Corp 

Analyzing Mixed-Effects Models with S-PLUS, February 2000, Statistical Short Course offered by 

MathSoft, San Francisco, CA 

Advanced General Linear Models with an Emphasis on Mixed Models, November 1999, Statistical Short 

Course offered by SAS Institute, Dallas TX

Spatial And Spatio-Temporal Data Analysis in Epidemiology, August 1999, A statistical Short Course 

offered by the Research School for Animal Production and Health, Foulum, Denmark 

Advanced Quantitative Veterinary Epidemiology, July 1998, Graduate Level Epidemiology Training 

offered by the Department of Population Medicine, University of Guelph. 

POSTDOCTORAL EXPERIENCE 

2001-present Associate Professor, Faculty of Toxicology, Texas A&M University, College Station, TX 

1998-present Associate Professor, Dept. of Large Animal Clinical Science, College of Veterinary 


2000-2001 Associate Professor, visiting in Department of Statistics, Texas A&M Univ., College Station 

TX 

1992-1998 Assistant Professor, Dept. of Large Animal Medicine and Surgery, College of Veterinary 


1991-1992 Clinical Assistant Professor, Department of Large Animal Medicine and Surgery, College of 

Veterinary Medicine, Texas A&M University, College Station, TX 

1988-1991 DVSc student, Department of Population Medicine, University of Guelph, Guelph, Ontario, 

Canada. 

1987-1988 Associate Veterinarian (small animals), Kanata Animal Hospital, Kanata, Ontario, Canada 

1983-1987 Owner and veterinarian (mixed practice), Antigonish Animal Hospital, Antigonish, Nova 

Scotia, Canada 

SELECTED PEER-REVIEWED PUBLICATIONS. 

Thompson, J.A., Zu, L., Carozza, S.E. An evaluation of spatial and multivariate covariance among 

childhood cancer histotypes in Texas (United States). Cancer Causes and Control. 18:105-113, 2007. 

Thompson, J.A., Leite, R.M.H., Gonçalves, V.S.P., Leite, R.C., Bandeira, D.A., Herrmann, G.P., Moreira, 

E.C., Prado, P.E.F., Lobato, Z.I.P., Brito, C.P.T., Lage, A.P. Spatial hierarchical variances and age 

covariances for seroprevalence to Leptospira interrogans serovar hardjo, BoHV-1 and BVDV for cattle in 

the State of Paraíba, Brazil. Preventive Veterinary Medicine 76(3-4):290-301, 2006. 

S.L. Graham, K.S. Barling, S. Waghela, H.M. Scott and J.A. Thompson. Spatial distribution of antibodies 

to Salmonella enterica serovar typhimurium O antigens in bulk milk from Texas dairy herds. Preventive 

Veterinary Medicine 69 (1-2):53-61, 2005. 

A.J. Roussel, M.C. Libal, R.L. Whitlock, K.S. Barling, T.B. Hairgrove and J.A. Thompson. Prevalence 

and risk factors for paratuberculosis among beef cattle in Texas. Journal of the American Veterinary 

Medical Association 226 (5):773-778, 2005. 

J.A. Thompson, S.E. Brown, T. Riddle, J.C. Seahorn and N.D. Cohen. Use of a Bayesian risk-mapping 

technique to estimate spatial risks for mare reproductive loss syndrome in Kentucky. American Journal 

of Veterinary Research 65 (1):17-20, 2005. 

J.A. Thompson, C.C. Love, K.L. Stich, S.P. Brinsko, T.L. Blanchard and D.D. Varner. A Bayesian 

approach to prediction of stallion daily sperm output. Theriogenology 62(9):1607-1617, 2004.

NAME 



ecastiglioni 


Provide the following information for the key personnel and other significant contributors. 



Professor & Head, Dept. Vet. Integrat. Biosci. 

Assoc. Dean for Undergraduate Education 



DEGREE 


YEAR(s) 


University of Texas-El Paso B.S. 1975 Biology 

University of Texas-Galveston Ph.D. 1979 Hum. Genet. & Cell Biol. 

University of California at Los Angeles Postdoc 1980-1982 Develop. Neurobiol. 


Professional Experience & Employment: 

1982-1987 Assistant Professor, Texas A&M University 

1987-1994 Associate Professor, Texas A&M University 

1989-1990 Visiting Associate, Professor University of Texas Health Science Center, San Antonio 

1990-present Faculty of Neuroscience and Faculty of Toxicology, Texas A&M University 

1994-present Professor, Texas A&M University 

1996-1998 Asst. Dean for Undergraduate Education, Texas A&M University 

1998-present Assoc. Dean for Undergraduate Education, Texas A&M University 

1998-1999 Interim Department Head, Texas A&M University, Vet. Anatomy & Public Health 

1999-present Department Head, Texas A&M University, Vet. Integrative Biosciences (dept. renamed 2004) 

Selected Professional Activities (Last 3 Years): 

Editorial Board of International Journal of Developmental Neuroscience, 2000-present 

Associate Editor, Neurotoxicology, 2004-present 

NIOSH SOH Study Section (2003-present); NSF Graduate Fellowships Review Panel 2000-2002, 2005 

Society of Toxicology 42nd Annual Meeting, Invited chair, Continuing Education Course in “Basic 

Neurotoxicology” Baltimore, MD, March 20-25, 2004 

5th International Conference on Early Toxicity Screening: Strategies and Approaches for Toxicity Screening in 

Drug Discovery and Development, Invited speaker, San Diego, CA, February 21-23, 2005 

Society of Toxicology 43nd Annual Meeting, Invited speaker, symposium on “Neurotoxicity of 

Organophosphates & Carbamates,” New Orleans, LA, March 20-25, 2005 

10th Meeting of the International Neurotoxicology Association, Invited chair, symposium on “In Vitro Models 

and Biosensors for Detecting Neurotoxicity," Porvoo, Finland, June 26-July 1, 2005 

International Society for Neurochemistry-European Society for Neurochem Congress, Invited chair, colloquium 

on “Astrocytes in Neurodegenerative Disease Processes,” Innsbruck, Austria, August 21-26, 2005 

TestSmart Developmental Neurotoxicity Testing meeting, sponsored by Center for Alternatives to Animal 

Testing (CAAT), Johns Hopkins University, Invited plenary speaker, Washington, DC, March 13-15, 2006 

B. Publications (Last 3 Years): 

Hong, MS, SJ Hong, R Barhoumi, RC Burghardt, KC Donnelly, JR Wild, V Venkatraj, E Tiffany-Castiglioni. 

2003. Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by 

organophosphorus compounds. Toxicol. App. Pharm. 186:110-118. 

Qian, Y, E Tiffany-Castiglioni. 2003. Lead-induced endoplasmic reticulum (ER) stress responses in the 

nervous system. Neurochemical Res. 28:153-162. 

Tang, YK, KC Donnelly, MG Mumtaz, E Tiffany-Castiglioni. 2003. Neurotoxicity of polycyclic aromatic 

hydrocarbons and simple chemical mixtures. J. Tox. Env. Health 66:919-940.

Cho, TM, E Tiffany-Castiglioni. 2004. Neurofilament 200 as an indicator of differences between mipafox and 

paraoxon sensitivity in SY5Y neuroblastoma cells. J. Tox. Env. Health 67:987-1000. 

Donnelly, KC, R Lingenfelter, L Cizmas, MH. Falahatpisheh, Y Qian, Y Tang, S Garcia, K Ramos, E Tiffany- 

Castiglioni, MG Mumtaz. 2004. Toxicity assessment of complex mixtures remains a goal. Env. Toxicol. 

Pharmacol 18:135–141. 

Tiffany-Castiglioni, E, Y Qian. 2005. Astroglia and lead neurotoxicity. In: The Role of Glia in Neurotoxicity, 

2nd Ed. M Aschner and LG Costa, eds. CRC Press, Boca Raton. pp. 417-438. 

Qian, Y, E Tiffany-Castiglioni. 2005. GRP78 compartmentalized redistribution in Pb-treated glia: role of 

GRP78 in lead-induced oxidative stress. Neurotoxicology 26:267-75. 

Qian, Y, Y Zheng, L Abraham, KS Ramos, E Tiffany-Castiglioni. 2005. Differential profiles of copper-induced 

ROS generation in human neuroblastoma and astrocytoma cells. Mol. Brain Res. 134:323-332. 

Qian, Y, Y Zheng, KS Ramos, E Tiffany-Castiglioni. 2005. The involvement of copper transporter in leadinduced 

oxidative stress in astroglia. Neurochemical Research 30:429-438. 

Tiffany-Castiglioni, E, JS Venkatraj, Y Qian. 2005. Genetic polymorphisms and mechanisms of neurotoxicity: 

overview. Neurotoxicology 26:641-649. 

Harry, G J, E Tiffany-Castiglioni. 2005. Evaluation of neurotoxic potential by use of in vitro systems. Expert 

Opin. Drug Metab. Toxicol. 1(4):1-13. 

Yang, W., E Tiffany-Castiglioni. 2005. The bipyridyl herbicide paraquat produces oxidative stress-mediated 

toxicity in human neuroblastoma SH-SY5Y cells: relevance to the dopaminergic pathogenesis. J.Tox. Env. 

Health 68, 1939-1961. 

Cho, TM, J. R Wild, KC Donnelly, E Tiffany-Castiglioni. 2006. Remediation of organophosphorus neurotoxicity 

in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH). J. Tox. Env. Health 69, 1413-1429. 

Tiffany-Castiglioni, E, JS Venkatraj, Y Qian, J. R Wild. 2006. In vitro models for testing organophosphateinduced 

neurotoxicity and remediation. In: Toxicology of Organophosphate & Carbamate Pesticides, RC 

Gupta, ed. Elsevier, Amsterdam. pp. 315-337. 

Tiffany-Castiglioni, E, S. Hong, S., Y Qian, Y Tang, KC Donnelly. 2006. COMMENTARY: In vitro models for 

assessing neurotoxicity of mixtures. Neurotoxicology 27: 835-839. 

Qian, Y, JS Venkatraj, R Barhoumi, R Pal, A. Datta, JR Wild, E Tiffany-Castiglioni. 2007. Comparative noncholinergic 

neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human 

neuroblastoma and astrocytoma cell lines. Toxicol. App. Pharm, 219:162-171. 

White, LD, DA Cory-Slechta, ME Gilbert, E Tiffany-Castiglioni, NH Zawia, M Virgolini, A Rossi-George, SM 

Lasley, Y Qian, MR Basha. New concepts in the neurotoxicology of lead. Toxicol. App. Pharm. In press. 

Books 

Tiffany-Castiglioni, E, ed. 2004. In Vitro Toxicology: Principles and Challenges. Humana Press. 

Selected Earlier Publications (of 70 total peer-reviewed papers) 

Hong, SJ, CA Grover, SH Safe, E Tiffany-Castiglioni. GD Frye. 1998. Halogenated aromatic hydrocarbons 

inhibit CA1 field excitatory post synaptic potentials in rat hippocampal slices. Tox. Appl. Pharm. 148:7-13. 

Qian, Y, E Tiffany-Castiglioni, ED. Harris. 1998. Sequence of a Menkes type Cu transporting ATPase from rat 

C6 glioma cells: Comparison of the rat protein with other mammalian Cu transporting ATPases. Mol. Cell. 

Biochem. 181:49-61. 

Legare, ME, R Barhoumi, E Hebert, GR Bratton, RC Burghardt, E Tiffany-Castiglioni. 1998. Analysis of Pb 2+ 

entry into cultured astroglia. Toxicol. Sci. 46:90-100. 

Qian, Y, G Mikeska, ED. Harris, E Tiffany-Castiglioni. 1999. Effect of lead exposure and accumulation on 

copper homeostasis in cultured C6 rat glioma cells. Toxicol. Appl. Pharm.138:41-49. 

Lindahl, LS., L Bird, ME Legare, G Mikeska, GR Bratton, E Tiffany-Castiglioni. 1999. Differential ability of 

astroglia and neuronal cells to accumulate lead: Dependence on cell type and on degree of differentiation. 

Toxicol. Sci., 50:236-243.




NAME 

Turner, Nancy Delane 






DEGREE 


YEAR(s) 


Texas A&M University, College Station BS 1978 Animal Science 

Texas A&M University, College Station MS 1984 Animal Nutrition 

Texas A&M University, College Station PhD 1995 Nutrition 

Positions and Honors 


1984-1995 Research Associate, Animal Science Department, Texas A&M University; 

Research Supervisor: Dr. F. M. Byers 

1996-1998 Assistant Research Scientist, Animal Science Department, Texas A&M University; 

Research Collaborator: Dr. J. R. Lupton 

1998-2003 Research Assistant Professor, Animal Science Department, Texas A&M University 

2003-2004 Associate Professor, Animal Science Department, Texas A&M University 

2004-present Associate Professor, Nutrition and Food Science Department, Texas A&M University 

2205-present Chair, Intercollegiate Faculty of Nutrition 


1997- Ad hoc reviewer for Journal of Nutrition 

1998 Ad hoc reviewer for Journal of Animal Science 

1999-2002 Appointed to editorial board for Journal of Animal Science 

1999- Associate Editor of ASNS – Nutrition Notes 

2000- Ad hoc reviewer for Nutrition and Cancer 

2000- Ad hoc reviewer for American Journal of Clinical Nutrition 

2001-2004 Member of the Executive Committee for the Faculty of Nutrition 

2001-2004 Member of NSBRI Teacher Academy Advisory Board 

2002-2004 Vice-Chair of the Faculty of Nutrition 

2002- Ad hoc reviewer for Biochimica et Biophysica Acta 

2002-2003 Member of review panel for USDA/NRI program 

2003- Member of the Radiation Steering Committee of NASA/NSBRI 

2003-2005 Secretary/Treasurer of Diet & Cancer Research Interest Section of ASNS 

2003 Ad hoc reviewer for the National Medical Research Council of Singapore 

2003 Ad hoc reviewer for Cancer Letters 

2004 Appointed Co-leader of the Health Benefits group in the “Foods for Health” Program - VFIC 

2004 Ad hoc reviewer for USDA’s NRI program on Improving Human Nutrition for Optimal Health 

2004 Re-elected to Executive Committee of the Faculty of Nutrition, 2004-2007 

2004 Reappointed as Vice-Chair of Faculty of Nutrition, 2004-2007 

2005 Elected to serve as Chair, Intercollegiate Faculty of Nutrition, 2/2005-1/2008 

2005 Ad hoc reviewer for USDA’s NRI program on Bioactive Food Components for Optimal Health 

2006 Ad hoc panel member for the Chemo/Dietary Prevention Study Section, NIH 

Honors 

58 th Edition of Who’s Who in America, 21 st Edition of Who’s Who in the World 

1995 Vice Chancellor’s Award in Excellence for Research Support 

1998 Ethel Ashworth-Tsutsui Memorial Award for Mentoring

Member of: American Society for Nutritional Sciences, American Physiological Society, American 

Association for Cancer Research, The New York Academy of Sciences, American Association for the 

Advancement of Science, Society for Experimental Biology and Medicine 


1. Turner, N.D., J. Zhang, L.A. Davidson, J.R. Lupton, and R.S. Chapkin. 2002. Oncogenic ras alters 

sensitivity of colonocytes to butyrate and fatty acid mediated growth arrest and apoptosis. Cancer Lett. 

186:29-35. 

2. Turner, N.D., L.A. Braby, J. Ford, and J.R. Lupton. 2002. Opportunities for nutritional amelioration of 

radiation-induced cellular damage. Nutrition 18:904-912. 

3. Lupton, J.R., N.D. Turner. 2003. Dietary fiber and coronary disease: Does the evidence support an 

association? Curr. Atheroscler. Rep. 5:500-505. 

4. Hong, M.Y., R.S. Chapkin, L.A. Davidson, N.D. Turner, J.S. Morris, R.J. Carroll, and J.R. Lupton. 2003. 

Fish oil enhances targeted apoptosis during colon tumor initiation in part by down regulating bcl-2. Nutr. 

Cancer 46:44-51. 

5. Morris, J.S., N. Wang, J.R. Lupton, R.S. Chapkin, N.D. Turner, M.Y. Hong, and R.J. Carroll. 2003. 

Understanding the relationship between carcinogen-induced DNA adduct levels in distal and proximal 

regions of the colon. Adv. Exp. Med. Biol. 537:105-116. 

6. Apanasovich, T.V., S. Sheather, J.R. Lupton, N. Popovic, N.D. Turner, R.S. Chapkin, and R.J. Carroll. 

2003. Testing for spatial correlation in binary data with application to aberrant crypt foci in colon 

carcinogenesis. Biometrics 59:752-761. 

7. Wu, G., Y.-Z. Fang, S. Yang, J.R. Lupton, N.D. Turner. 2004. Glutathione metabolism and its implications 

for health. J. Nutr. 134:489-492. 

8. Sanders, L.S., C.E. Henderson, M.Y. Hong, R. Barhoumi, R.C. Burghardt, R.J. Carroll, N.D. Turner, R.S. 

Chapkin, J.R. Lupton. 2004. Pro-oxidant environment of the colon compared to the small intestine may 

contribute to greater cancer susceptibility. Cancer Lett. 208:155-161. 

9. Davidson, L.A., D.V. Nguyen, R.M. Hokanson, E.S. Callaway, R.B. Isett, N.D. Turner, E.R. Dogherty, J.R. 

Lupton, R.J. Carroll, R.S. Chapkin. 2004. Chemopreventive n-3 polyunsaturated fatty acids reprogram 

genetic signatures during colon cancer initiation and progression in the rat. Cancer Res. 64:6797-6804. 

10. Sanders, L.M., C.E. Henderson, M.Y. Hong, R. Barhoumi, R.C. Burghardt, N. Wang, C.M. Spinka, R.J. 

Carroll, N.D. Turner, R.S. Chapkin, and J.R. Lupton. 2004. Enhancement of reactive oxygen species by 

dietary fish oil and attenuation of antioxidant defenses by dietary pectin coordinately heighten apoptosis in 

rat colonocytes. J. Nutr. 134:3233-3238. 

11. Leyk, M. D.V. Nguyen, S.N. Attoor, E.R. Dougherty, N.D. Turner, L.K. Bancroft, R.S. Chapkin, J.R. Lupton, 

and R.J. Carroll. 2004. Comparing automatic and manual image processing in FLARE assay analysis for 

colon carcinogenesis. Stat. Appl. Genet. Mol. Biol. 4:online Article 5. 

12. Zhou, G.-D., N. Popovic, J.R. Lupton, N.D. Turner, R.S. Chapkin, and K.C. Donnelly. 2005. Tissuespecific 

attenuation of endogenous DNA I-compounds in rats by carcinogen azoxymethane: Possible role 

of dietary fish oil in colon cancer prevention. Cancer Epidemiol. Biomarkers Prev. 14:1230-1235. 

13. Vanamala, J., G. Cobb, N.D. Turner, J.R. Lupton, K.S. Yoo, L.M. Pike, and B.S. Patil. 2005. Bioactive 

compounds of grapefruit (Citrus paradises cv Rio Red) respond differently to postharvest irradiation, 

storage and freeze drying. J. Agric. Food Chem. 53:3980-3985. 

14. Hong, M.Y., N.D. Turner, R.J. Carroll, R.S. Chapkin, and J.R. Lupton. 2005. Differential response to DNA 

damage may explain different cancer susceptibility between small and large intestine. Exp. Biol. Med. 

230:464-471. 

15. Hong, M.Y., L.K. Bancroft, N.D. Turner, L.A. Davidson, M.E. Murphy, R.J. Carroll, R.S. Chapkin, and J.R. 

Lupton. 2005. Fish oil decreases oxidative DNA damage by enhancing apoptosis in rat colon. Nutr. 

Cancer 52:166-175. 

16. Liu, L.D., N. Wang, J.R. Lupton, N.D. Turner, R.S. Chapkin, and L.A. Davidson. 2005. A two-stage 

normalization method for partially degraded mRNA microarray data. Bioinformatics 21:4000-4006. 

17. Vanamala, J., T. Leonardi, B.S. Patil, S.S. Taddeo, M.E. Murphy, L.M. Pike, R.S. Chapkin, J.R. Lupton, 

and N.D. Turner. 2006. Suppression of colon carcinogenesis by bioactive compounds in grapefruit. 

Carcinogenesis 27:1257-1265.




NAME 

Cheryl Lyn Walker 




CHWALKER 



DEGREE 


YEAR(s) 


University of Colorado, Boulder, CO B.A. 1977 Molecular, Cell & Devel. Biology 

University of Texas Health Science Center 

Southwestern Medical School, Dallas, TX Ph.D. 1984 Cell Biology 

Research and Professional Experience: 

1988 - 1992 Scientist I, Department of Cellular and Molecular Toxicology, Chemical Industry Institute of 

Toxicology, Research Triangle Park, NC 

8/92 - 1998 Associate Professor, University of Texas, M.D. Anderson Cancer Center, Science Park- 

Research Division, Smithville, TX 

9/98 - 2002 Professor, University of Texas, M.D. Anderson Cancer Center, Science Park - Research 

Division, Smithville, TX 

2002 - Present Ruth and Walter Sterling Professor of Carcinogenesis, University of Texas, MD Anderson 

Cancer Center – Science Park Research Division, Smithville, TX 

4/96 - Present Director, Molecular Genetics and Environmental Carcinogenesis Research Core, NIEHS 

Center for Research on Environmental Disease 

Professional Honors and Activities: 

Member, Nat’l. Academy of Sciences Comm. on Emerging Issues & Data on Environ. Contamin. (2002-2007) 

Board of Scientific Councilors, National Toxicology Program (2002-2005) 

Board of Scientific Councilors, National Cancer Institute (2001-2006) 

Member, Board of Directors, Society of Toxicology (2001-2003) 

Member, NIH US – Japan Cooperative Medical Exchange Program Panel on Toxicogenomics and 

Environmental Carcinogenesis (1999-2003), Chairman (2001-2005) 

Chairman, Women's Health and the Environment: Advances in Uterine Leiomyoma Research Conf. (1999) 

Co-Chair, Gordon Conference on Hormone Action in Development and Cancer (2005) 

Chairman, Gordon Conference on Mechanisms of Toxicity (1998) 

President, Women in Cancer Research, American Association for Cancer Research (1993) 

Molecular Genetics Study Section, US Army Breast Cancer Research Prog. (1995-1997, Chairman 1998,99) 

Associate Editor, Cancer Research (1995-present); Associate Editor, Carcinogenesis (1994-1996) 

Molecular Carcinogenesis (1992-present), Senior Editor, Molecular Cancer Research (2002-present), Senior 

Editor, Toxicogenomics Environmental Health Perspectives (2002-2005) 

Chair, International Scientific Advisory Board, Tuberous Sclerosis Alliance (2005-present) 

The Dallas/Fort Worth Living Legend Faculty Achievement Award in Basic Research (2006-2007) 

Selected peer-reviewed publications (from over 100) (in chronological order). 

Hunter, D.S., Hodges, L.C., Vonier, P.M., Fuchs-Young, R., Gottardis, M., and Walker, C.L. Estrogen Receptor 

Activation via activation function 2 predicts agonism of xenoestrogens in normal and neoplastic cells of the 

uterine myometrium. Cancer Res. 59: 3090-3099, 1999. 

Hodges, L.C., Bergerson, J.S., Hunter, D.S., and Walker, C.L. Estrogenic effects of organochlorine pesticides 

on uterine leiomyoma cells in vitro. Toxicological Sciences 54: 355-364, 2000. 

Walker, C.L., Burroughs, K.D., Davis, B., Sowell, K., Everitt, J.I., Fuchs-Young, R. Preclinical evidence for 

therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma. J. Soc. Gyn. Invest. 7: 

249-256, 2000. 

Gamage, S.D., Bischoff, E.D., Burroughs, K.D., Lamph, W.W., Gottardis, M.M., Walker, C.L., and Fuchs- 

Young, R. Efficacy of LGD1069 (Targretin), a retinoid X receptor-selective ligand, for treatment of uterine 

leiomyoma. J. Pharm. Exp. Therapeutics 295: 677-681, 2000. 

Cesen-Cummings, K., Copeland, J.A., Barrett, J.C., Walker, C.L., and Davis, B.J. Pregnancy, parturition, and 

prostaglandins: defining uterine leiomyomas. Environ. Health Perspect. 108: 817-820, 2000. 

Hunter, D.S., Hodges, L.C., Eagon, P.K., Vonier, P.M., Fuchs-Young, R., Bergerson, J.S., and Walker, C.L. 

Influence of exogenous estrogen receptor ligands on uterine leiomyoma: evidence from an in vitro/in vivo

animal model for uterine fibroids. Environ. Health Perspect. 108: 829-834, 2000. 

Kleymenova, E., Ibraghimov-Beskrovnaya, O., Kugoh, H., Everitt, J., Xu, H., Kiguchi, K., Landes, G., Harris, P., 

and Walker, C. Tuberin-dependent membrane localization of polycystin-1: A functional link between 

polycystic kidney disease and the TSC2 tumor suppressor gene. Molecular Cell 7: 823-832, 2001. 

Walker, C.L., Cesen-Cummings, K., Houle, C., Baird, D., Barrett, J.C. and Davis, B. Protective effect of 

pregnancy for development of uterine leiomyoma. Carcinogenesis 22:2049-2052, 2001. 

Burroughs, K.D., Howe, S.R., Okubo, Y., Fuchs-Young, R., LeRoith, D., and Walker, C.L. Disregulation of 

insulin-like growth factor-I signaling in uterine leiomyoma. Journal of Endocrinology 172: 83-93, 2002. 

Irani, C., Goncharova, E.A., Hunter, D.S., Walker, C.L., Panettieri, R.A., Krymskaya, V.P. Phosphatidylinositol 

3-kinase but not tuberin is required for PDGF-induced cell migration. Am J Physiol Lung Cell Mol Physiol 

282: L854-62, 2002. 

Hunter, D. S., Klotzbucher, M., Kugoh, H., Cai, S. L., Mullen, J. P., Manfioletti, G., Fuhrman, U., and Walker, C. 

L. Aberrant Expression of HMGA2 in Uterine Leiomyoma Associated with Loss of TSC2 Tumor Suppressor 

Gene Function. Cancer Res, 62: 3766-3772, 2002. 

Goncharova, E.A., Goncharov, D.A., Eszterhas, A., Hunter, D.S., Glassberg, M.K., Yeung, R.S., Walker, C.L., 

Noonan, D., Kwiatkowski, D.J., Chou, M.M., Panettieri Jr., R.A., Krymskaya, V.P. Tuberin regulates p70 S6 

kinase activation and ribosomal protein S6 phosphorylation: a role for the TSC2 tumor suppressor gene in 

pulmonary lymphangioleiomyomatosis (LAM). J. Biol. Chem. 277:30958-67, 2002. 

Hodges, L.C., Houston, K.D, Hunter, D.S., Fuchs-Young, R, Zhang, Z., Wineker, R.C., and Walker, C.L. 

Transdominant suppression of estrogen receptor signaling by progesterone receptor ligands in uterine 

leiomyoma cells. Mol. Cell. Endocrinol. 196: 11-20, 2002. 

Astrinidis, A., Cash, T.P., Hunter, D.S., Walker, C.L., Chernoff, J., and Henske, E.P. Tuberin, the tuberous 

sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion, and migration. 

Oncogene 21: 8470-8476, 2002. 

Liu, M.Y., Cai, S., Espejo, A., Bedford, M.T. and Walker, C.L. 14-3-3 interacts with the tumor suppressor 

tuberin at Akt phosphorylation site(s). Cancer Res 62: 6475-6580, 2002. 

Cesen-Cummings, K., Houston, K.D., Copland, J.A., Moorman, V.J., Walker, C.L., and Davis, B.J. Uterine 

leiomyomas express myometrial contractile-associated proteins involved in pregnancy-related hormone 

signaling, J. Soc. Gynecol. Investig. 10: 11-20, 2003. 

Houston, K.D., Copland, J.A, Broaddus, R., Gotardis, M.M., Fischer, S.M., Walker, C.L. Inhibition of estrogen 

receptor activity in uterine leiomyoma cells by PPAR ligands. Cancer Res. 63: 1221-1227, 2003. 

Hodges, L.C., Cook, J.D., Lobenhofer, E.K., Li, L., Bennett, L., Bushel, P.R., Aldaz, C.M., Afshari, C.A., and 

Walker, C.L. Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast 

cancer cells. Molecular Cancer Res. 1:300-306, 2003. 

Cai S., Everitt J.I., Kugo H., Cook J., Kleymenova E. and Walker C.L. Polycystic Kidney Disease as a Result of 

Loss of the Tsc2 Tumor Suppressor Gene during Development. American Journal of Pathology. 162:457-68, 

2003. 

Finlay, G.A., Hunter, D.S., Walker, C.L., Paulson, K.E., and Fanburg, B.L. The regulation of PDGF production 

and ERK activation by estrogen is associated with TSC2 gene expression. Am. J. Physiol. Am. J. Physiol. 

Cell Physiol, 285:C409-418, 2003. 

Kleymenova, E., Everitt, J.I., Pluta, L., Portis, M., Gnarra, J.R., and Walker, C.L. “Susceptibility to Vascular 

Neoplasms but No Increased Susceptibility to Renal Carcinogenesis in Vhl Knockout Mice. Carcinogenesis 

25: 309-315, 2004. 

Cook, J.D., Davis, B., Cai, S.L., Conti, C.J., Barrett, J.C., Walker, C.L. Interaction Between Genetic 

Susceptibility and Early Life Environmental Exposure Determines Tumor Suppressor Gene Penetrance. 

Proceedings of the National Academy of Sciences, 102: 8644-8649, 2005. 

Walker, C.L. and Stewart, E.A. Uterine Fibroids: The Elephant in the Room. Science, 308: 1589-1592, 2005. 

Cai, S.-L., Tee, A.R., Short, J.D., Bergeron, J.M., Kim, J., Shen, J., Guo, R., Johnson, C.L., Kiguchi, K., 

Walker, C.L. Activity of the Tumor Suppressor Tuberin is Inhibited by AKT-mediated Phosphorylation and 

Membrane Partitioning. Journal of Cell Biology, 173(2):279-289, 2006. 

Mally, A, Walker, C.L., Everitt, J.I., Dekant, W., Vamvakas, S. Analysis of renal cell transformation following 

exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-l-cysteine in vitro. Toxicology,22:108- 

118, 2006. 

Book Chapters (from 17): 

Walker, C.L. Modeling Genetic Susceptibility in Rodents. In: Cellular and Molecular Toxicology, J.P. Vanden 

Heuvel and G.H. Perdew (eds), Vol XX Comprehensive Toxicology Series, Academic Press, 2001. 

Walker, C. Role of Hormonal and Reproductive Factors in the Etiology and Treatment of Uterine Leiomyoma. 

In: Reproductive Hormones and Human Health. Recent Progress in Hormone Research. Means A.R. (ed), 

The Endocrine Society, Vol 57, 2002.

NAME 

Wang, Naisyin 





nwangtamu 


Professor of Statistics & Toxicology 



DEGREE 


YEAR(s) 


National Tsing-Hua University, Taiwan B.A. 1986 Mathematics 

Ohio State University, Columbus M.A.S. 1987 Applied Statistics 

Cornell University, Ithaca M.S. 1989 Statistics 

Cornell University, Ithaca Ph.D. 1992 Statistics 



1991 Visiting Ph.D. Student, Australia National University 

Dec 1992 Visiting Scholar, Biostatistics Department, Johns Hopkins University 

1994-1995 Visiting Scholar, Biostatistics Department, Harvard School of Public Health 

Dec 1997 Visiting Scholar, Humboldt Universitat zu Berlin, Germany 

1999-2000 Visiting Scholar, Fred Hutchinson Cancer Research Center and Statistics Department, 

University of Washington 

1998-current Associate & Full Professor, Faculty of Toxicology, Texas A&M University 

1992-current Assistant, Associate & Full Professor, Statistics, Texas A&M University 

Honors 

2003 Elected member, International Statistical Institute 

2003 Distinguished Achievement Award in Research, TAMU Association of Former Students 

2002 Journal of American Statistical Association invited discussion paper 

2001 Fellow, American Statistical Association 

2001-2005 University Fellow, Texas A&M University 

2000 International Biometrics Society (IBS-ENAR) Meeting special invited paper 

1997-2002 NIH FIRST award 

1997 Journal of American Statistical Association Editor's invited paper 


Nguyen, D.V., Arpat, A.B., Wang, N. and Carroll, R.J. (2002) DNA microarray experiments: biologicaland 

technological aspects. Biometrics, 58, 701-717. 

Morris, J.S., Wang, N., Lupton, J.R., Chapkin, R.S., Turner, N.D., Hong, M.Y. and Carroll, R.J. (2002) A 

bayesian analysis of colonic crypt structure and coordinated response incorporating missing crypts. 

Biostatistics, 4, 529-546. 

Wang, N. and Raftery, A.E. (2002) Robust covariance estimation via nearest neighbor cleaning. Journal of the 

American Statistical Association, (with discussion) 97, 994-1006, Rejoinder, 1016-1019. 

Wang, N. (2003) Marginal Nonparametric kernel regression accounting for within-subject correlation. 

Biometrika, 90, 43-52. 

Balagurunathan, Y.,Wang, N., Dougherty E.R., Nguyen, D.V., Chen, Y., Bittner, M.L., Trent, J.M. and Carroll, 

R.J. (2004) Noise factor analysis for cDNA microarrays. Journal of Biomedical Optics, 9, 663-678. 

Lin, X., Wang, N., Alan H. Welsh and Carroll, R.J. (2004) Equivalent kernels of smoothing splines in 

nonparametric regression for clustered data. Biometrika, 91, 177-193.

Eubank, R.L., Huang, C., Mu~noz Maldonado, Y., Wang, N., and Wang, S. (2004) Smoothing Spline 

Estimation in Varying Coefficient Models. Journal of the Royal Statistical Society, Series B, 66, 653-667. 

Hu, Z., Wang, N. and Carroll, R.J. (2004) Pro_le-Kernel versus Back_tting in the Partially Linear Models for 

Longitudinal/Clustered Data. Biometrika, 91, 251-262. 

Eubank, R.L., Huang, C., Mu~noz Maldonado, Y. Wang, N., and Wang, S. (2004) Smoothing Spline Estimation 

in Varying Coefficient Models. Journal of the Royal Statistical Society, Series B, 66, 653-667. 

Sanders, L.M., Henderson, C.E., Hong, M.H., Barhoumi, R. Burghardt, R.C., Wang, N., Spinka, C.M., Carroll1, 

R.J., Turner, N.D., Chapkin, R.S. and Joann, L.R. (2004) Enhancement of reactive oxygen species by 

dietary fish oil and attenuation of antioxidant defenses by dietary pectin coordinately heighten apoptosis 

in rat colonocytes. Journal of Nutrition, 134, 3233-3238. 

Switzer, K.C., Fan, Y.Y., Wang, N., McMurray, D.N. and Chapkin, R. S. (2004) Dietary n-3 polyunsaturated 

fatty acids promote activation-induced cell death in Th1-polarized murine cd4+ t cells. Journal of Lipid 

Research, 45, 1482-1492. 

Davidson L.A., Nguyen D.V., Hokanson R.M., Callaway E.S., Isett R.B., Turner N.D., Dougherty E.R., Wang 

N., Lupton J.R., Carroll R.J., Chapkin RS (2004) Chemopreventive n-3 polyunsaturated fatty acids 

reprogram genetic signatures during colon cancer initiation and progression in the rat. Cancer Research, 

64 (18), 6797-6804. 

Discussion of "Conditional and marginal models: another view" by Lee, Y and Nelder, J.J. (2004) Statistical 

Science, 231-232. 

Wang, N., Carroll, R.J. and Lin, X. (2005) Efficient semiparametric marginal estimation for 

longitudinal/clustered data. Journal of the American Statistical Association, 147-157. 

Liang, H. and Wang, N. (2005) Large sample theory in a semiparametric partially linear errors-in-variables 

model. Statistica Scinica, 99-117. 

Ng, Y. Barhoumi, R., Tjalkens, R.B., Fan, Y.Y., Kolar, S., Wang, N., Lupton, J.R. and Chapkin, R.S. (2005) The 

role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in 

colonocytes. Carcinogenesis, 26:1914-1921. 

Liu, L.D., Wang, N., Lupton, J.R., Turner, N.D., Chapkin, R.S. and Davidson, L.A. (2005) A two-stage 

normalization method for partially degraded mrna microarray data. Bioinformatics, 4000-4006. 

Chiou, J.M. and Wang, N. (2005) Accounting for correlations in varying coefficient models. 

Li, E., Wang, N. and Wang, N.Y. (2005) Joint Models for A Primary Endpoint and Multivariate Longitudinal 

Data. 

Hu, Z. and Wang, N. (2005) Semiparametric latent covariate mixed models with application to a colon 

carcinogenesis study. 

Ma, Y., Chiou, J.M. and Wang, N. (2006) Efficient semiparametric estimator for heteroscedastic partially linear 

models. Biometrika, in press. 

Liang, F. and Wang, N. (2006) Dynamic Hierarchical Clustering of Gene Expression Profiles. Pattern 

Recognition, in press. 

Liang, F., Liu, C. and Wang, N. (2006) A Sequential Bayesian Procedure for Differential Gene Expression. 

Statistica Sinica, in press. 

Zhang, P., Kim, W., Zhou, L., Wang, N., Ly, L.H, McMurray, D.N. and Chapkin, R.S. (2006) Dietary fish oil 

inhibits antigen-specific Th1 cell development by suppression of clonal expansion. Journal of Nutrition, 

136:2391-2398, 2006. 

Li, Y., Wang, N., Hong, M., Turner, N.D., Lupton, J.R. Carroll, R.J. (2006) Nonparametric Estimation of 

Correlation Functions In Longitudinal And Spatial Data, With Application To Colon Carcinogenesis 

Experiments. 

Cohen, N.D., Stanley, S.D., Arthur, R.M. and Wang, N. (2006) Factors influencing prerace serum concentration 

of total carbon dioxide in Thoroughbred horses racing in California. Equine Vet J, 38:543-548. 

Cohen, N.D., Toby, E., Roussel, A.J., Murphey, E.L. and Wang, N. (2006) Are feeding practices associated 

with duodenitis-proximal jejunitis? Equine Vet J, 38:526-531. 

Turner, N.D., Vanamala, J., Leonardi, T., Patil, B.S., Murphy, M.E., Liu, Y.C., Wang, N., Pike, L.M., Chapkin 

R.S. and Lupton, J.R. (2006) Comparison of the chemoprotection conferred by grapefruit and isolated 

bioactive compounds against colon cancer. In: Potential Health Benefits of Citrus, pp. 121-129. B.S. Patil, 

N.D. Turner, E.G. Miller, and J.S. Brodbelt (eds.) American Chemical Society, Washington, DC.




NAME 

Wild, James R. 



Professor and TAES Research Fellow 



DEGREE 


YEAR(s) 


University of California-Davis BA 1967 Zoology 

University of California-Riverside PhD 1971 Cell Biology 

University of California-Riverside NIH Postdoctoral Fellow 1972 Biochemistry 



1972-1975 Research Microbiologist/Biochemist, LT, MSC, USNR. Pathobiology Division, 

U.S. Navy Medical Research Institute, Bethesda 

1975-1998 Assistant/Associate/Full Professor of Biochemistry and Genetics, 

1984-87/93-94 TAMU Chairman, Faculty of Genetics, TAMU 

1987-1990 Professor and Interim Head, Biochemistry and Biophysics 

1989-1992 Executive Associate Dean for Academic Programs, COALS 

1992-1996 Member, National Research Council, Board of Army Science and Technology, Committee on 

Review and Evaluation of Chemical Stockpile Disposal Program 

1992-1999 Director, Texas A&M University/Army Research University Research Intitiative Program 

Factors Influencing the Degradation of Military Toxic Wastes 

1994-2000 Professor and Head of Department 

2001-present Coordinator, Chemical Threat Management Team, DREAMS Program, Disaster Relief 

and Emergency Medical Systems. TAMU/UT-HSC- US Army MRMC. 

Honors 

1975 U.S. Navy Achievement Award; LT, MSC, USNR, Naval Medical Research Institute 

1981 University-level Faculty Distinguished Achievement Award - Teaching, TAMU 

1986-87 Texas A&M University Teacher/Scholar Award, University Honors Program 

1988-89 Distinguished Teaching Award, College of Agriculture and Life Sciences 

1992- Master Teacher - Master Teacher Council (College of Agriculture and Life Sciences) 

1993 Award for Teaching Excellence, Excellence in College and University Teaching, Southern 

Region, National Association of State Universities and Land Grant Colleges 

1993-94 Burton International Research Fellow, Texas A&M University 

1998 Elected Fellow, American Association for the Advancement of Science 

1998-99 Texas Agricultural Program Research Faculty Fellow, Texas A& University System 

2002 Wells Fargo University Honors Outstanding Faculty Advisor (university-level) 

B. Selected peer-reviewed publications. (Total of 137). 

M Zourob, A Simonian, JR Wild, S Mohr, NJ Goddard. (2007). Optical Leaky Waveguide Biosensors for the 

Detection of Organophosphorus Pesticides. Analytica Chimica Acta. 132:114-120. Epub 2006 Dec 11. 

Y. Qian, J. Venkatraj, R. Barhoumi, R. Pal, A. Datta, J.R. Wild, and E. Tiffany-Castiglioni. (2007). Comparative 

Non-Cholinargic Neurotoxic Effects of Paraoxon and Diisopropyl Flourophosphate (DFP) on Human 

Neuroblastoma and Astrocytoma Cell Lines. Toxicology and Applied Pharmacology. 219:162-171. 

Baskin, S.I., I. Petrikovics, J.R. Wild, M.E. Wales, G.E. Platoff, G.A. Rockwood, and B.A. Logue. (2006). 

Spectrophotometric Analysis of the Cyanide Metabolite 2-aminothiazoline-4-carboxylic acid (ATCA). 

Toxicological Methods and Mechanism. In Press. 

M.E. Wales, C.S. McDaniel, A.L. Everett, J.W. Rawlins, M.D. Blanton, A. Busquets, J.R.Wild, and C.F.

Gonzalez. (2006) Antimicrobial Additives for Reactive Surfaces Coatings. Paint Coatings Industry. June 

2006, 62-70. 

D.J. Self, E.M. Ellison, H.J. Saatkamp, Jr., and J.R. Wild. (2006). Teaching Ethical Issues in Genetics: 

Assessment of Development of Moral Reasoning Skills. Annals of Behavioral Science and Medical 

Education 12:21-25. 

C. Steven McDaniel, Jesse McDaniel, Melinda E. Wales, James R. Wild. (2006). Enzyme-based additives for 

paints and coatings. Progress in Organic Coatings. 55:182-188. 

A.L. Simonian and J.R. Wild. (2006). Enzyme-based Biosensors for the Direct and Discriminative Detection of 

CW Nerve Agents and Related Agricultural Pesticides. Issues in Homeland Security. Vol. 1, The Science 

of Homeland Security. Edited by: Sandy Amass, Arun Bhunia, Alok Chaturvedi, Dan Dolk, Srinvas 

Peeta, Mike Atallah.. Purdue University Press. In Press. 

L. Viveros, S. Paliwal, D. McCrae, J.R. Wild, and A.I. Simonian. (2006). A fluorescence-based biosensor for 

the detection of organophosphate pesticides and chemical warfare agents. Sensors and Actuators 

B:Chemical. 115:150-157. 

E. Tiffany-Castiglioni, V. Venkatraj, Y. Qian, and J.R. Wild. (2006). In vitro models for testing 

organophosphate-induced neurotoxicity and remediation. In Toxicology of Organophosphate & 

Carbamate Compounds. 22:315-338. 

I. Petrikovics, S.I. Baskin, T-C. Cheng, R. Yin, M. Szilasi, B.A. Logue, J.C. Jaszberenyi, M.E. Wales, J.R. Wild, 

and J.L. Way. (2005). Development of an Enzyme-based, Intravascular Defense Against OP 

Neurotoxins: Dendritic Polymers Coupled with 2-PAM and Atropine. Nanotoxicology, 01:1-9. 

J.K. Grimsley, B. Calamini, J.R. Wild, and A.D. Mesecar. (2005) Structural and mutational studies of 

organophosphorus hydrolase reveal a cryptic and functional allosteric-binding site. Arch. Biochem. 

Biophys. 442:169-179. 

T.M. Cho, J.R. Wild, K.C. Donnelly, and E. Tiffany-Castiglioni. (2006) Degradation of Organophosphorous 

Neurotoxicity in SY5Y Neuroblastoma Cells by Organophosphorus Hydrolase (OPH). J Tox Environ 

Health. 69:1413-1429. 

J. Ha, A.Z.Diaz, J.R. Wild, and C.R. Engler. (2005). Biodegradation of Hazardous Compounds Using 

Immobilized Microorganisms. ASAE Paper 057005. 

M. Rodríguez, T.A. Good, M.E. Wales, J.P. Hua, and James R. Wild. 2005. Modeling Allosteric 

Regulation of de nove Pyrimidine Biosynthesis in E. coli. Theoretical Biology. 234(3):299-310. 

C.S. McDaniel, J., McDaniel, M.E. Wales, and J.R. Wild. 2005. “Biocatalytic Coatings.” Paint and Coatings 

Industry, February 2005:26-33. 

A.L. Simonian, A.W. Flounders and J. R. Wild. 2004. “A FET-based Biosensor for The Direct Detection of 

Organophosphate Neurotoxins.” Electroanalysis.16:1896-1906. 

R.S. Gold, J. Maxim, D.J. Halepaska, Jr., M.E. Wales, D.A. Johnson, and J.R. Wild. 2005. “Electron beam 

irradiation as a protection against the environmental release of recombinant molecules for biomaterials 

applications.” Journal of Biomaterials. 16:79-89. 

M.S. Hong, S.J. Hong, R. Barhoumi, R.C. Burghardt, K.C. Donnelly, J.R. Wild, V. Venkatraj, E. Tiffany- 

Castiglioni. 2003. “Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by 

organophosphorus compounds.” Toxicol. Appl. Pharmacol., 186:110-118. 

A.L. Simonian, J.K. Grimsley, A.W. Flounders J. S. Schoeniger, Tu-Chen Cheng, J.J. DeFrank and J. R. Wild. 

2002. “Enzyme-based Biosensor for the Direct Detection of Fluorine-containing Organophosphates.” 

Analytica Chimica Acta, 442:15-23. 

V.B. Arakelian, J.R. Wild, and A.L. Simonian. 2002. “The Influence of External Environment Fluctuations on the 

Signal Formation of Microbiosensors”. Biosensors and Bioelectronics, 16: 69-72. 

A.L. Simonian, A. Revzin, J.R. Wild, J. Elkind, and M. V. Pishko. 2002. “Characterization of Oxidoreductase/ 

Redox Polymer Electrostatic Film Assembly by Surface Plasmon Resonance Spectroscopy, FTIR, and 

Ellipsometry on Gold”. Anal.Chim.Acta 466:201-212. 

J-W Kim, EI Rainina, WW Mulbry, CR Engler, and JR Wild. 2002. “Enhanced-Rate Biodegradation of 

Organophosphate Neurotoxins by Immobilized Non-Growing Bacteria.” Biotechnology Prog 18:429-436. 

A.L. Simonian, Revzin A, Wild JR., Elkind J, and Pishko MV. 2002. “Characterization of Oxidoreductase/ 

Redox Polymer Electrostatic Film Assembly by Surface Plasmon Resonance Spectroscopy, FTIR, and 

Ellipsometry on Gold.” Anal.Chim.Acta 466:201-212.




NAME 

Cody L. Wilson 



Adjunct Associate Professor 



DEGREE 


YEAR(s) 

Texas A&M University BS 1993 Biochemistry 

Texas A&M University PhD 1997 Toxicology 




1998 – 2000 Research Toxicologist, Naval Health Research Center Detachment (Toxicology) 

1999 – 2003 Adjunct Assistant Professor, Preventive Medicine and Biometrics, Uniformed Services University 

2001 – 2002 Chemical Defense Fellow, US Army Center for Health Promotion and Preventive Medicine 

2002 – 2004 Toxicologist, Navy Environmental and Preventive Medicine Unit No. 2 

2004 – 2006 Research Scientist, Texas Agricultural Experiment Station, College Station, TX 

2005 – Adjunct Associate Professor, Environmental and Occupational Health, Texas A&M Health Science 

Center, College Station, TX 

2005 – Member, Intercollegiate Faculty of Toxicology, Texas A&M University, College Station, TX 

2006 – Master Toxicologist, RJ Reynolds Tobacco Co., Winston-Salem, NC 


1997 – 2004 U.S. Navy, Active Duty Commissioned Officer 

1999 – 2000 Toxicologist, City of Dayton, Ohio Environmental Advisory Board (Volunteer Activity) 

1999 – 2000 Subject Matter Expert, Office of the Assistant Secretary of the Navy for Installations and Environment 

1999 – Society of Toxicology (Full Member) 

1999 – 2000 US Military Tri-Service Toxicology Consortium Steering Committee 

2002 – 2004 Society of Toxicology Task Force on Biological and Chemical Terrorism Preparedness 

Honors 

2000 Occupational Health Research award, Navy Occupational Health & Preventive Medicine Workshop 

2002 Environmental Programs Research award, Navy Occupational Health & Preventive Medicine Workshop 

2004 Rear Admiral Charles S. Stephenson Award for Excellence in Navy Preventive Medicine 


1. X. Wang, J. Thomsen, C. Wilson, and S. Safe. Ah-nonresponsiveness in MDA-MB-231 human breast cancer cells is 

related to a truncation in the Arnt protein. Organohalogen Compounds (21): 329-332, 1994 

2. C. Wilson, J. Thomsen, D. Hoivik, and S. Safe. Aryl hydrocarbon (Ah)-nonresponsiveness in estrogen receptornegative 

MDA-MB-231 cells is associated with expression of a variant Arnt protein. Arch. Biochem. Biophys. 346: 65-73, 

1997. 

3. A. McDougal, C. Wilson, and S. Safe. Induction of estradiol 2-hydroxylase activity in MCF-7 human breast cancer 

cells by pesticides and carcinogens. Environ. Toxicol. Pharmacol. 3: 195-199, 1997. 

4. A. McDougal, C. Wilson, and S. Safe. Inhibition of 7, 12-dimethylbenz[a]anthracene-induced rat mammary tumor 

growth by aryl hydrocarbon receptor agonists. Cancer Lett. 120: 53-63, 1997. 

5. D. Hoivik, C. Wilson, W. Wang, K. Willett, and S. Safe. Studies on the relationship between estrogen receptor

content, glutathione-S-transferase-pi expression, and induction of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and drug 

resistance in human breast cancer cells. Arch. Biochem. Biophys. 348: 174-182, 1997. 

6. D. Hoivik, K. Willett, C. Wilson, and S. Safe. Estrogen does not inhibit 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin mediated 

effects in MCF-7 and Hepa-1c1c7 cells. J. Biol. Chem. 272: 30270-30274, 1997. 

7. S. Safe and C. Wilson. Health effects and risk assessment of halogenated aromatic hydrocarbons. Cent. Eur. J. Pub. 

Health. 6: 113-116, 1997. 

8. P. Fernandez, C. Wilson, D. Hoivik, and S. Safe. Altered phenotypic characteristics of T47D human breast cancer 

cells after prolonged growth in estrogen-deficient medium. Cell Biol. Int. 22: 623-633, 1998. 

9. C. Wilson and S. Safe. Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic 

responses. Toxicol. Pathol. 26: 657-671, 1998. 

10. K. Willett, C. Wilson, J. Thomsen, W. Porter, and S. Safe. Polynuclear aromatic hydrocarbon and 2, 3, 7, 8-TCDD 

binding proteins in marine molluscs. Aquatic Toxicol. 48: 51-64, 1999. 

11. K. R. Still, G. B. Briggs, P. Knectges, W. Alexander, and C. L. Wilson. Risk assessment in Navy deployment 

toxicology. Human Eco Risk Assess. 6: 1125-1136, 2000. 

12. J. Rossi III, G. D. Ritchie, C. L. Wilson, P. L. Knechtges, A. F. Nordholm, J. Lin, W. K. Alexander, K. R. Still. 

Application of neurobehavioral toxicology methods to the military deployment toxicology assessment program. Drug 

Chem Toxicol. 23: 113-138, 2000. 

13. F. Witzmann, R. L. Carpenter, G. D. Ritchie, C. L. Wilson, A. F. Nordholm, and J. Rossi III. Toxicity of chemical 

mixtures: Proteomic analysis of persisting liver and kidney protein alterations induced by repeated exposure of rats to 

JP-8 jet fuel vapor. Electrophoresis 21: 2138-2147, 2000. 

14. G. Ritchie, K. R. Still, W. K. Alexander, A. F. Nordholm, C. L. Wilson, J. Rossi III, and D. R. Mattie. A review of the 

neurotoxicity of selected hydrocarbon fuels. J. Toxicol. Environ. Health, Part B. 4: 223-312, 2001. 

15. C. Qin, C. Wilson, C. Blancher, M. Taylor, S. Safe, and A. L. Harris. Association of ARNT splice variants with 

estrogen receptor-negative breast cancer, poor induction of vascular endothelial growth factor under hypoxia, and poor 

prognosis. Clin. Cancer Res. 7: 818-823, 2001. 

16. C. Wilson, D. Arfsten, and B. Spargo. Human and environmental health issues related to use of radiofrequency 

chaff. Navy Medicine Sept-Oct Issue, 2001. 

17. C. L. Wilson, D. Arfsten, R. Carpenter, W. Alexander and K. R. Still. Effect of Navy chaff release on aluminum levels 

in the Chesapeake Bay. Ecotox. Env. Safety 52: 137-142, 2002. 

18. D. P. Arfsten, C. L. Wilson, and B. J. Spargo. Radiofrequency chaff: the effects of its use in training on the 

environment. Ecotox. Env. Safety 53: 1-11, 2002. 

19. C. L. Wilson. Molecular switch circuits in toxicology: a dimmer switch for dioxin. Toxicol. Sci. 78: 178-180, 2004. 

20. D. P. Arfsten, D. T. Burton, D. J. Fisher, J. Callahan, C. L. Wilson, K. R. Still, B. J. Spargo. Assessment of the 

aquatic and terrestrial toxicity of five biodegradable polymers. Environ Res. 94: 198-210, 2004.

NAME 

Wilson, Emily 





wilsonem 





DEGREE 


YEAR(s) 

Utah State University, Logan, Utah B.S. 1980 Biology 

Utah State University, Logan, Utah M.S. 1984 Biochemistry 

Emory University, Atlanta, GA Ph.D. 1987 Biochemistry 

Vanderbilt University, Nashville, TN Postdoc 1991 Pharmacology 



1982-1983 Grad Research Asst; Dept of Chemistry and Biochem, Dr. Jon Y. Takemoto, Utah State Univ 

Logan, UT 

1984-1987 Grad Research: Dept of Biochem, Dr. J David Lambeth, Emory Univ School of Med, Atlanta, GA 

1987-1988 Postdoctoral Trainee; Natl Cancer Institute Training Grant, "Chemical and Biochemical Basis of 

Cancer", Vanderbilt Univ School of Medicine 

1987-1991 Research Associate, Dept of Pharmacology, Dr. D. Martin Watterson, Vanderbilt Univ School of 

Medicine, Nashville, TN 

1988-1991 Associate; Howard Hughes Medical Inst, Dr. D. Martin Watterson, Vanderbilt Univ School of 

Medicine, Nashville, TN 

1991-1997 Asst Research Biochemist; Cardiovascular Research Inst and the Div of Nephrology, Univ of 

California, San Francisco 

1997-present Asst Prof: Dept of Med Physiology, Texas A&M Univ System HSC, College Station, TX 


Wilson E, Laster SM, Gooding LR and Lambeth JD Platelet derived growth factor stimulates phagocytosis and 

blocks agonists-induced activation of the neutrophil oxidative burst. Proc Natl Acad Sci USA 84, 2213- 

2217, 1987. 

Wilson E, Rice WG, Kinkade JM, Merrill AH, Jr, Arnold RR and Lambeth JD. Protein kinase C inhibition by 

sphingoid long-chain bases: effects on secretion in human neutrophils. Arch Biochem Biophys 259, 204- 

214, 1987. 

Wilson E, Wang E, Mullins RE, Liotta DC, Lambeth JD and Merrill AH, Jr. Modulation of the free sphingosine 

levels in human neutrophils by phorbol esters and other factors. J Biol Chem 263, 9304-9309, 1988. 

Shoemaker MO, Lau W, Shattuck RL, Kwiatkowski AP, Matrisian PE, Guerra-Santos L, Wilson E, Lukas TJ, 

Van Eldik L and Watterson DM. Use of DNA sequence, mutant analysis and antisense 

oligodeoxynucleotides to examine the molecular basis of non-muscle myosin light chain kinase 

autoinhibition, calmodulin recognition and activity. J Cell Biol 111, 1117-1125, 1990. 

Hinrichsen R, Wilson E, Lukas T, Craig T, Schultz J and Watterson DM. Analysis of the molecular basis of 

calmodulin defects that affect ion channel mediated cellular responses by using site specific mutagenesis 

and microinjection. J Cell Biol 111, 2537-2542, 1990. 

Chabre O, Conklin BR, Lin HY, Lodish HF, Wilson E, Ives HE, Catanzariti L, Hemmings BA and Bourne HR. A 

recombinant calcitonin receptor independently stimulates cAMP and Ca 2+ /inositol phosphate signaling 

pathways. Mol Endo 6, 551-556, 1992. 

Peters KG, Marie J, Wilson E, Ives HE, Escobedo J, Delrosario MD, Mirda D and Williams LT. An FGF 

Receptor Point Mutation That Abolishes Phosphatidylinositol Turnover and Ca ++ Mobilization but not 

Mitogenesis. Nature 358, 678-681, 1992. 

Wilson E, Mai Q, Sudhir K, Weiss RH and Ives HE. Mechanical strain induces growth of vascular smooth

muscle cells via autocrine action of PDGF. J Cell Biol 123 741-747, 1993. 

Sudhir K, Wilson E, Chatterjee K and Ives HE. Mechanical strain and collagen potentiate the mitogenic activity 

of angiotensin II in rat vascular smooth muscle cells. J Clin Invest 92, 3003-3007, 1993. 

Clyman RI, Peters KG, Chen YQ, Escobedo J, Williams LT, Ives HE and Wilson E. Phospholipase Cγ 

activation, phosphotidylinositol hydrolysis, and calcium mobilization are not required for FGF receptormediated 

chemotaxis. Cell Adhesion and Comm 1, 333-342, 1994. 

Ma Y-H, Reusch P, Wilson E, Escobedo JA, Fantl WJ, Williams LT, Ives HE. Activation of Na + /H + exchange by 

platelet derived growth factor involves phosphatidylinositol-3' kinase and phospholipase Cγ. J Biol Chem 

269, 30734-30739, 1994. 

Wilson E, Sudhir K and Ives HE Mechanical strain is sensed by vascular smooth muscle cells through 

interaction with adhesion proteins. J Clin Invest 96 2364-2372, 1995. 

Reusch P, Wagday H, Reusch R, Wilson E and Ives HE Mechanical strain increases smooth muscle and 

decreases nonmuscle myosin in rat vascular smooth muscle cells. Circ Res 79 1046-1053, 1996. 

Wilson E, Vives F, Collins T and Ives HE. Mechanical strain enhances expression of the PDGF-A through a 

complex interaction of transcription factors Egr-1 and Sp1 with a proximal 92 pb region of the promoter . 

Hypertension 31 [Part 2], 170-175, 1998. 

Morawietz H, Ma Y-H, Vives F, Wilson E, Sukhatme VP, Holtz J and Ives HE. Mechanical strain induces early 

growth response gene-1 expression in vascular smooth muscle cells. Circ Res 84: 678-687, 1999. 

Ling S, Dai A, Ma Y-H, Wilson E, Chatterjee K, Ives HE, Sudhir K. Matrix-dependent gene expression of Egr-1 

and PDGF A regulate angiotensin II-induced proliferation in human vascular smooth muscle cells. 

Hypertension 34: 1141-1146, 1999. 

Wu X, Davis GE, Meininger GA, Wilson E and Davis MJ (2001) Regulation of the L-type calcium channel by 

α β integrin requires signaling between focal adhesion proteins. J Biol Chem 276, 30285-30292. 

Davis MJ, Wu X, Nurkiewicz TR, Kawasaki J, Gui P, Hill MA and Wilson E. (2001) Regulation of ion channels 

by protein tyrosine phosphorylation. Am J Physiol Heart Circ Physiol 281: H1835-H1862. 

Wilson E, Parrish AR, Williams ES, Bral CM, Mitchell DM and Ramos KS. Collagen suppresses proliferative 

phenotype of allylamine injured vascular smooth muscle cells. Atherosclerosis 162(2): 289-297, 2002. 

Wilson E and Meininger GA. Extracellular matrix changes and vascular smooth muscle signaling in 

mechanisms of cardiovascular aging. In Advances in Cell Aging and Gerontology series, Elsevier, 11, 183- 

200, 2003. 

Hayes, H. Kossman, M.S., Wilson, E. and Zawieja, D.C. Development and characterization of endothelial cells 

from rat microlymphatics. Lymphatic Research and Biology 1(2): 101-119. 

Humphrey JD and Wilson E. (2003) A potential role of activation in smooth muscle mechanotransduction 

during early hypertension. Journal of Biomechanics. 36: 1595-1601. 

Jones SA, Patterson JL, Chao J-T, Ramos KS, Wilson E (2004) Modulation of cyclin-dependent kinase 

inhibitor proteins and ERK 1/2 activity in allylamine-injured vascular smooth muscle. J Cell Biochem 91: 

1248-125. 

Chao JT, Meininger GA, Patterson, JL, Jones SA, Partridge CR, Neiger JD, Williams ES, Kaufman SJ, Ramos 

KS, Wilson E (2004) Regulation of Alpha 7 integrin expression in vascular smooth muscle by injury induced 

atherosclerosis. Am J Physiol Heart Circ Physiol 287: H381-H389. 

Tinsley JT, Yuan SY and Wilson E (2004) Isoform-specific knockout of endothelial myosin light chain kinase: 

closing the gap on inflammatory lung disease. Trends in Pharmacol Sciences 25: 64-66. 

Gleason RL, Gray S, Wilson E and Humphrey JD (2004) A multiaxial computer-controlled organ culture and 

biomechanical device for mouse carotid arteries. J of Biomech Eng 126: 787-795. 

Wilkerson MK, Lesniewski LA, Golding EM, Bryan RM Jr, Amin A, Wilson E and Delp MD (2005) Simulated 

microgravity enhances cerebral artery vasoconstriction and vascular resistance through an endothelial 

nitric oxide mechanism. Am J Physiol Heart Circ Physiol 288: H1652-H1661. 

Neiger JD, Crow TY, Partridge CR, Williams ES, Chao JT, Meininger GA, Ramos GA, Wilson E. (2005) 

Modulation of α4 integrin mRNA levels is coupled to deficient in vasomotor function in rat arterioles by 

allylamine. Life Sci 76: 1895-1905. 

Partridge CR, Williams ES, Barhoumi R, Tadesse MG, Johnson CD, Lu KP, Meininger GA, Wilson E, Ramos 

KS. (2005) Novel genomic targets in oxidant-induced vascular injury. J Mol Cell Cardiol 38: 983-96.

Appendix K 

Current Student Publications

IFT Current Graduate Student Peer-Reviewed Publications 

Atrayee Banerjee 

Rose R, Banerjee A and Ramaiah SK. Development and characterization of a 

lipopplysaccharide mediated neutrophilic hepatitis model in Sprague-Dawley rats. J 

Comp Med. (submitted). 

Rose R, Banerjee A and Ramaiah SK. Calpain inhibition attenuates iNOS production and 

midzonal hepatic necrosis in a repeated dose model of endotoxemia in rats. Tox Path. 

(in press). 

Banerjee A, Burghardt RC, Johnson GA, White FJ and Ramaiah SK. Potential role of 

osteopontin (SPP-1) as a predictive biomarker in a rat model of Alcoholic 

Steatoheaptitis. Tox Path. 34(4): 373-384. 2006. 

Banerjee A, Apte UM, Smith R and Ramaiah SK. Higher neutrophil infiltration mediated by 

osteopontin is a likely contributing factor to the increased susceptibility of females to 

alcoholic liver disease. J Pathol. 208(4): 473-485. 2006. 

Apte UM, Banerjee A, McRee R, Wellberg E, Ramaiah SK, Role of Osteopontin in Hepatic 

Neutrophil Infiltration during Alcoholic Steatohepatitis, Toxicol. Appl. Pharmacol. 207(1): 

25-38. 2005. 

Xinsheng Gu 

Xinsheng G, Ke S, Liu D, Sheng T, Thomas PE, Rabson AB, Gallo MA, Xie W and Tian Y. 

Role of NF-κB in regulation of PXR-mediated gene expression: a mechanism for the 

suppression of cytochrome P-450 3A4 by proinflammatory agents. J Biol Chem. Jun 

30;281(26):17882-9. 2006. Epub 2006 Apr 10. 

Zhu ZL, Xinsheng G, Lu G, Chen Y, Sun A. The selective Excluding Mechanism Study of 

Coordination Chemistry of 03A Traditional Chinese Medicine with Pb 2+ . Shanghai Trace 

Elements. 1(1):15-17. 2000. 

Xinsheng G, Li S, Chen B, Shi X, Chen Y, Sun A. Mechanism of No.03 drug of TCM 

discharging Pb without disturbing levels of other trace elements. Jiangxi Yiyao (Supp), 

144. 1994. 

Tanya Gustafson 

Kwak HI, Gustafson T, Metz RP, Laffin B, Schedin P and Porter WW. Inhibition of breast 

cancer growth and invasion by single-minded 2s. Carcinogenesis [Epub ahead of print]. 

2006. 

Metz RP, Kwak H, Gustafson T and Porter W. Differential transcriptional regulation by 

mouse Singleminded2s. J Biol Chem 281:10839-48, 2006. 

Lahiri M, Gustafson TL, Majors ER and Freudenreich CH. Expanded CAG repeats activate 

the DNA damage checkpoint pathway. Mol Cell. 15(2):287-93, 2004. 

Denise Hill 

Mitchell LE, Etheredge AJ, Hill DS and Finnell RH. Spina Bifida. Encyclopedia of Molecular 

Mechanisms of Disease, Springer (In Press) 

Wlodarczyk BJ, Cabrera RM, Hill DS, Bozinov D, Zhu H and Finnell RH. Arsenic-induced 

gene expression changes in the neural tube of folate transport defective mouse 

embryos. Neurotoxicology. Apr 16. 2006. 

Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt R, Liu S, Hill D, Finnell R, 

Wlodarczyk B, Jordan V and Safe S. 3-Methylcholanthrene and other aryl hydrocarbon 

receptor agonists directly activate estrogen receptor alpha. Cancer Res. Feb 

15;66(4):2459-67. 2006.

Cabrera RM, Hill DS, Etheredge AJ and Finnell RH. Investigations into the etiology of neural 

tube defects. Birth Defects Res C Embryo Today. Dec;72(4):330-44. 2004. 

Hiromi Hosako 

Hosako H, Little SA, Barrier M and Mirkes PE. Teratogen-induced activation of p53 in early 

postimplantation mouse embryos. Toxicological Sciences. (Submitted). 

Matthew Kelley 

Sumaya C, Carrillo-Zuniga G, Kelley M, May M, Zhu L and Donnelly KC. Linking Research 

to Health Promotion in Texas Colonias. American Journal of Health Studies. Accepted. 

Brian Laffin 

Kwak H-I, Gustafson T, Metz RP, Laffin B, Schedin P and Porter WW. Inhibition of 

Breast Cancer Growth and Invasion by Single-minded 2s. Carcinogenesis, Epub 

ahead of print, 2006. 

Metz RP, Kwak H-I, Gustafson T, Laffin B and Porter WW. Differential Transcriptional 

Regulation by Mouse Single-minded 2s. J Biol Chem. Apr 21;281(16):10839-48. 

2006. 

Metz RP, Qu X, Laffin B, Earnest D and Porter WW. Circadian Clock and Cell Cycle 

Gene Expression In Mouse Mammary Epithelial Cells and in the Developing Mouse 

Mammary Gland. Dev Dyn. Jan;235(1):263-71. 2006. 

Boyeon Lee 

Lee B, Pine M, Johnson L, Rettori V, Hiney JK and Dees WL. Manganese Acts Centrally to 

Activate Reproductive Hormone Secretion and Pubertal Development in Male Rats. 

Reproductive Toxicology 2006. (in press). 

Pine M, Lee B, Dearth R, Hiney JK and Dees WL. Manganese Acts Centrally to Stimulate 

Luteinizing Hormone Secretion: A Potential Influence on Female Pubertal Development. 

Toxicol Sci. Jun;85(2):880-5. 2005. 

Wan-Ru Lee 

Chen CC, Lee W-R and Safe S. Egr-1 is activated by 17β-estradiol in MCF-7 cells by 

mitogen-activated protein kinase-dependent phosphorylation of ELK-1. J Cell Biochem, 

93(5): p. 1063-74. 2004. 

Lee, W-R, Chen CC, Liu S and Safe S. 17β-Estradiol (E2) induces Cdc25A gene expression 

in breast cancer cells by genomic and non-genomic pathway. J Cell Biochem, in press 

2006. 

Rebecca Lingenfelter 

Donnelly KC, Lingenfelter RA, Cizmas L, Falahatpisheh M, Qian Y, Tang Y, Garcia S, 

Ramos K, Tiffany-Castiglioni E, Mumtaz M: Toxicity Assessment of Complex 

Mixtures Remains a Goal. Environ Tox and Pharm, 18:135-141. 2004. 

Christine Naspinski 

White P, Naspinski C, Maertens R, Whynot C and Chen G. Mutagenic hazards of indoor 

air. (submitted). 

Sabitha Papineni 

Chintharlapalli S, Papineni S, Jutooru I, Safe S. Synthetic Glycyrrhetinic acid derivative 

activate Peroxisome Proliferator-Activated Receptor γ (PPARγ) and induce Kruppel-Like 

Factor 4 in colon cancer cells. 2006. (in preparation).

Chintharlapalli S, Papineni S, Ramaiah S, Liu S and Safe S. Betulinic Acid Inhibits Prostate 

Cancer Growth Through Inhibition of Specificity Protein Transcription Factors. Nature 

Medicine. 2006. (Submitted) 

Chintharlapalli S, Papineni S, Safe S. 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes 

Inhibit Growth, Induce Apoptosis, and Decrease the Androgen Receptor in LNCaP 

Prostate Cancer Cells Through Peroxisome Proliferator-Activated Receptor γ- 

Independent Pathways. Mol Pharmacol. 2006. (in revision). 

Safe S and Papineni S. The role of xenoestrogenic compounds in the development of 

breast cancer. Trends Pharmacol Sci. Aug;27(8):447-54. 2006. 

Chintharlapalli S, Papineni S and Safe S. 1,1-Bis(3'-indolyl)-1-(psubstitutedphenyl)methanes 

Inhibit Colon Cancer Cell and Tumor Growth Through 

Peroxisome Proliferator-Activated Receptor γ- Dependent and -Independent Pathways. 

Mol Cancer Ther. May;5(5):1362-70. 2006. 

Chintharlapalli S, Papineni S, Baek SJ, Liu S and Safe SH. 1,1-Bis(3'-indolyl)-1-(psubstitutedphenyl)methanes 

Are Peroxisome Proliferator-Activated Receptor γ Agonists 

But Decrease HCT-116 Colon Cancer Cell Survival Through Receptor-independent 

Activation of Early Growth Response-1 and NAG-1. Mol Pharmacol. 68(6):1782-92. 

Epub Sep 9. 2005. 

Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K and Safe S. Activation of 

Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induces apoptosis 

through nuclear pathways. J Biol Chem. 280(26):24903-14. 2005. 

Chintharlapalli S, Papineni S, Konopleva M, Andreef M, Samudio I and Safe S. 2-Cyano- 

3,12-dioxoolean-1,9-dien-28-oic Acid (CDDO) and Related Compounds Inhibit Growth of 

Colon Cancer Cells Through Peroxisome Proliferator-Activated Receptor γ-Dependent 

and -Independent Pathways. Mol Pharmacol. 68(1):119-28. 2005. 

Tracie Phillips 

Cizmas L, McDonald TJ, Phillips TD, Gillespie AM, Lingenfelter RA, Kubena LF, Phillips TD 

and Donnelly KC. Toxicity Characterization of Complex Mixtures using Biological and 

Chemical Analysis in Preparation for Assessment of Mixture Similarity. Environ. Sci. & 

Technol. Oct. 1; 38(19):5127-33, 2004. 

Gillespie AM, Zhou G-D, Phillips TD, He L-Y, McDonald T, Duncan B and Donnelly KC. 

Genotoxicity of sediments containing complex mixtures of PCBs and PAHs. 

Environmental & Molecular Mutagenesis. In preparation. 

John Taylor 

Brightsmith D, Taylor J and Phillips T. The roles of soil characteristics and toxin adsorption 

in avian geophagy. Oecologia. 2006. 

Kerry Thuett 

Bellum S, Thuett KA, Taylor RJ and Abbott LC. Assessment of mercury concentrations in 

mouse brain using different routes of administration and different tissue preparations. 

Toxicology Mechanisms and Methods. In Press. 

Carr JA, Gentles A, Smith EE, Goleman WL, Urquidi LJ, Thuett K, Kendall RJ, Giesy JP, 

Gross TS, Solomon KR and Van Der Kraak G. Response of larval Xenopus laevis to 

atrazine: assessment of growth, metamorphosis, and gonadal and laryngeal 

morphology. Environmental Toxicology & Chemistry 22, 396-405. 2003. 

Thuett KA, Roots EH, Mitchell LP, Gentles BA, Anderson T, Kendall RJ and Smith EE. 

Effects of in utero and lactational ammonium perchlorate exposure on thyroid gland 

histology and thyroid and sex hormones in developing deer mice (Peromyscus

maniculatus) through postnatal day 21. Journal of Toxicology & Environmental Health 

Part A 65 (24), 2119-2130. 2002. 

Thuett KA, Roots EH, Mitchell LP, Gentles BA, Anderson TA and Smith EE. In utero and 

lactational exposure to ammonium perchlorate in drinking water: effects on developing 

deer mice at postnatal day 21. Journal of Toxicology & Environmental Health Part A 65 

(15), 1061-1076. 2002. 

Kathryn Vanderlaag 

Vanderlaag K, Smith R, Higgins KJ and Safe S. Cell cycle arrest and growth inhibition of 

invasive \breast cancer cell growth by a novel series of C-substituted 1,1-bis(3’-indolyl)- 

1-(p-substitutedphenyl)methanes (in process). 

Higgins KJ, Liu S, Abdelrahim M, Yoon K, Vanderlaag K, Porter W, Metz RP and Safe S. 

Vascular endothelial growth factor receptor-2 expression is induced by 17β-estradiol in 

ZR-75 breast cancer cells by estrogen receptor α/Sp proteins. Endocrinology. 

Jul;147(7):3285-95. 2006. 

Abdelrahim M, Newman K, Vanderlaag K, Samudio I and Safe S. 3,3'-diindolylmethane 

(DIM) and its derivatives induce apoptosis in pancreatic cancer cells through 

endoplasmic reticulum stress-dependent upregulation of DR5. Carcinogenesis. 

Apr;27(4):717-28. 2006. 

Vanderlaag K, Samudio I, Burghardt R, Barhoumi R and Safe S. Inhibition of breast cancer 

cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'- 

dibromoDIM. Cancer Lett. May 18;236(2):198-212. 2006. 

Elizabeth Wellberg 

Apte UM, Banerjee A, McRee R, Wellberg E and Ramaiah SK. Role of osteopontin in 

hepatic neutrophil infiltration during alcoholic steatohepatitis. Toxicology and Applied 

Pharmacology 205 (1): 25-38. 2005. 

McIntosh AL, Atshaves BP, Wellberg E, Kuklev DV, Smith WL and Schroeder F. Uptake 

Kinetics of Fluorescent Long Chain n-3 and n-6 Fatty Acids in Intact Cells. FASEB 

Journal March 4; 19(4):A292. 2005. 

Shu Zhang 

Zhang S, Li X, Burghardt R, Smith R 3 rd and Safe SH. Role of estrogen receptor (ER) α in 

insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells. J Mol 

Endocrinol. Dec;35(3):433-47. 2005. 

Zhang S, Qin C and Safe SH. Flavonoids as aryl hydrocarbon receptor 

agonists/antagonists: effects of structure and cell context. Environ Health Perspect. 

Dec;111(16):1877-82. 2003. 

Li X, Zhang S and Safe S. Activation of kinase pathways in MCF-7 cells by 17β-estradiol 

and structurally diverse estrogenic compounds. J Steroid Biochem Mol Biol. Feb;98(2- 

3):122-32. 2006.

Appendix L 

Outcomes Assessment of the Toxicology 

Program Administered Through the IFT

OUTCOMES ASSESSMENT OF THE TOXICOLOGY PROGRAM ADMINISTERED 

THROUGH THE INTERDISCIPLINARY FACULTY OF TOXICOLOGY 

Contribution to University: The mission of the Toxicology Graduate Program administered 

though the Interdisciplinary Faculty of Toxicology (IFT) is to sustain excellence in graduate 

training and research by providing a stimulating environment in the interdisciplinary field of 

toxicology. Our mission contributes to Graduate Studies at Texas A&M University by providing 

mentors, who have developed internationally recognized research programs and a collegial 

interdisciplinary outlook on research and graduate training, to enable graduate students to 

obtain outstanding training in toxicology. Outstanding research opportunities exist in molecular 

and cellular toxicology, biochemical and endocrine toxicology, cancer causation and prevention, 

reproductive and developmental toxicology, neurotoxicology, environmental toxicology, and food 

safety. Education and research training in the Texas A&M University IFT is designed to prepare 

individuals to become successful, productive members of the scientific community and establish 

careers in academia, industry, and government. 

Contribution to IFT Mission: The Toxicology Graduate Program provides an outstanding 

academic and research environment for graduate students embarking on a path for research 

and teaching in the multidisciplinary field of toxicology. The program offers the opportunity to 

participate in original research designed to improve understanding mechanisms of action and 

toxicity of therapeutic and environmental agents and to discover new drugs. The training 

program emphasizes laboratory research skills including hypothesis testing, design of 

experiments, data interpretation, and critical evaluation of published data. 

Research foci include toxicogenomics, molecular mechanisms of hormone action and drug 

metabolism, endocrine disruptors, environmental causes of birth defects, anti-cancer 

pharmacology, and identification and mechanisms of action of toxic drugs and other chemicals 

found in our environment. 

Outcome Effective Date and Title: 

(Toxicology, Ph.D.) 1989 

1. FUNDAMENTAL KNOWLEDGE IN DISCIPLINE 

Students graduating with a Ph.D. in Toxicology will be able to demonstrate fundamental 

knowledge in the basic biomedical sciences, including toxicology, biological chemistry and 

cellular physiology, and functional proteomics and genomics. 

Courses in which outcome is achieved: 

A) Basic Environmental Toxicology (VIBS/PHEO 610) covering an overview of classes of 

chemicals, organ system responses, and environmental health 

B) Metabolic and Detoxication Mechanisms (VTPP 673) covering phase I and phase II drug 

metabolizing enzymes and molecular mechanisms of action of diverse drugs, toxins, and 

genotoxins with emphasis on interpretation of experimental data 

C) Genetic and Molecular Toxicology (VTPP 676) covering molecular mechanisms and adverse 

effects induced by exposure to environmental chemicals and therapeutic drugs. 

D) Food Toxicology (VIBS 619) covering health implications of toxic factors (natural as well as 

synthetic) in food: their source, nature, occurrence, distribution, toxicities, and mechanisms of 

action; research techniques and methodologies applicable to food safety. 

E) Scientific Ethics (VMID 686) covering a broad range of topics such as animal use, genetic 

testing, human research and medical ethics, review and scientific credit, scientific misconduct, 

digital imaging, assisted reproductive technologies and stem cell use, and others. 

Plus specialty courses (Chemical Hazards Assessment [PHEO/VIBS 605] which covers 

chemical and biological methods for testing hazardous chemicals and complex mixtures;

(Biodegradation and Bioremediation [VIBS 614] which covers microbiological, chemical, 

toxicological, environmental, engineering and technological aspects of biodegradation of 

environmental chemicals and how these principles relate to bioremediation. 

1A. COMPLETION OF REQUIRED COURSE WORK 

Measurement Criterion to be Met: 

All students will successfully complete required introductory and advanced coursework. 

Measurement Period Start Date and Title: 

1989, Ph.D. in Toxicology, Completion of required coursework 

Measurement Description: Students are expected to complete all required coursework 

with a minimum grade of B. 

Measurement Period End Date and Results/Actions: 

Date of Measurement: 09/30/2007 Criterion met: Yes or No 

Measurement Results: 

09/30/2007: Over the past five years, x of xx students earned a grade below B in either 

introductory or advanced coursework 

Measurement Actions: Academic deficiencies have to be corrected by the students. 

Also, the Graduate Program Director reviews the performance in required coursework to 

identify strengths and deficiencies in the program admission standards. Based on these 

reviews, the admission standards are modified to improve the overall quality of the 

program. 

1B. QUALIFYING EXAMINATION FOR ADMISSION TO CANDIDACY 

Criterion to be Met: 

All students will successfully demonstrate an understanding of the background of an 

original scientific problem in its widest sense, including an ability to critically read and 

evaluate current scientific literature, by passing their qualifying examination. All students 

will demonstrate understanding of core competencies in basic toxicology and 

environmental health sciences that include: 1) an understanding of molecular 

mechanisms of toxicity and factors that affect susceptibility, and 2) knowledge of risk 

assessment methods and approaches for preventing and controlling environmental 

hazards 

Measurement Period Start Date and Title: (Toxicology, Ph.D.) 

1989, Ph.D. in Toxicology, Satisfactory completion of preliminary examination 

Measurement Description: 

As part of the examination of qualifications for candidacy, students will be tested over 

fundamentals of toxicology covered in core courses in addition to other areas of 

competence agreed upon by the Chair and Members of the Graduate Advisory 

Committee. A written report of the results of the examination is sent to the Office of 

Graduate Studies and the IFT administrative coordinator. 


09/30/2007 Criterion met: Yes or No 


09/30/2007 

Over the past five years, xx of xx students passed their qualifying exam without 

condition. X passed with additional conditions required. 

If any action is to be taken for those with conditional passes or failures, we would 

describe here: 

Measurement Actions:

The Qualifying Examination Reports are reviewed by the Graduate Program Director to 

identify strengths and deficiencies in the Program. 

Based on an academic review of the IFT conducted in 1998, and discussion within the 

IFT Executive Committee, we have re-structured our toxicology curriculum to have 

students take the above referenced core courses, plus we have identified a number of 

elective courses which are highly recommended. 


(Toxicology, Ph.D.) 10/1/1999 

2. CONDUCT INDEPENDENT RESEARCH 

Students graduating with a Ph.D. in Toxicology will be able to conduct independent research in 

the theoretical and applied fields in basic biomedical sciences. 


A) Doctoral Level Dissertation Research (TOXI 691) 

B) Toxicology Seminar (VTPP 681) This required seminar series exposes students to research 

presented by researchers from other institutions hosted by IFT faculty and trainees as well as 

researchers from Texas A&M University. 

CERH Sponsored Workshops (Protein Technologies, Genomics, Image Analysis) 

Other training support (Each of the Texas A&M CERH Research Cores supports research 

training through sponsorship of seminar series that provide enrichment to trainees and new 

investigators. In addition, extensive training activities in the application of analytical techniques 

take place in each of the Facility Cores through formal introductory and advanced workshops 

that are conducted on a regular basis, as well as through one-on-one interactions associated 

with applications development and equipment training. IFT members possess a diverse toolbox 

of shared analytical expertise and a demonstrated interest in facilitating cross-training and 

technology transfer. A few selected examples of cross-training/technology transfer currently 

shared among IFT member laboratories include: a) members of Dr. Safe’s lab provide support 

to other laboratories interested in using chromatin immunoprecipitation (ChIP) assays, 

electrophoretic mobility shift assays (EMSAs), and custom chemical synthesis; b) the Spencer 

laboratory provide support in the application of in situ hybridization, antigen retrieval and 

histochemistry protocols, and surgical support using domestic animal models; c) the Parrish lab 

assists with the application of precision-cut tissue slice technology for cellular and molecular 

analysis of mechanisms of toxicity; d) the Donnelly laboratory assists investigators with 

utilization of a variety of assays such as the quantification of DNA adducts and the 

measurement of environmental chemicals in biological samples; e) the Porter lab supports 

investigators with the generation of retroviral expression constructs as well as design and 

implementation of rodent studies; f) the Tiffany-Castiglioni laboratory assists with cell/tissue 

culture training for establishment of cell lines and in vitro toxicology methods; g) the Dees 

laboratory shares expertise with small animal procedures such as gastric canula and gavage; h) 

the Chapkin laboratory assists investigators with quantitative RT-PCR in conjunction with the 

Genomics Facility Core; i) the Ramaiah laboratory assists with histopathology assessment; j) 

the Mirkes laboratory assists with the selection and implementation of a variety of apoptosis 

assays and evaluation of mouse embryo development; and k) the Burghardt laboratory assists 

with development of immunofluorescence protocols using multiple fluorophores, non-invasive 

vital imaging and multiparameter kinetic analyses of cellular homeostasis, and primary culture 

and cell line propagation. 

2A. PUBLICATION OF TWO PEER-REVIEWED ARTICLES 

Measurement Criterion to be Met:

All students will publish a minimum of two peer-reviewed articles in high impact journals 

by the time they graduate 


1989, Ph.D. in Toxicology, publication of research results 


An updated CV from each trainee is collected from trainees on an annual basis. 




09/30/2007: Over the past five years, x of xx graduating students met or exceeded the 

criterion. 

Furthermore, x% of graduates had published x or more articles, and on the average they 

published x.x publications/student. 

Measurement Actions: 

09/30/2007: In the past, no timelines were imposed for entrance into candidacy. This 

year, mentors and students have been informed that students are to enter into Ph.D. 

candidacy before the end of the 4 th year; within two years this will be pushed to the third 

year. 

09/30/2007: The Program Director will emphasize with the mentor and thesis committee 

the importance of identifying a research plan at the time of admission to candidacy. 

2B. PRESENTATION OF RESEARCH RESULTS AT ANNUAL IFT TOXICOLOGY 

FORUM 


All students in the Toxicology program who have completed one year of study in the 

program will present research results in platform or poster format at the annual IFT 

Toxicology Forum 


1989, Ph.D. in Toxicology, presentation of research results 


All toxicology students will submit an abstract for the meeting and students within two 

years of graduation will present platform talks. 




09/30/2007: Over the past five years, x of xx graduating students met the criterion. 


All students are meeting this criterion. The IFT Chair and Executive Committee will 

continue to encourage full participation at this annual local meeting by all IFT faculty. 

When funds are available, an internationally known toxicologist will be invited as keynote 

speaker and will be hosted by trainees. 

2C. PRESENTATION OF RESEARCH RESULTS AT REGIONAL AND/OR NATIONAL 

MEETINGS 


All students will present research results at a minimum of one regional (e.g., Gulf Coast 

Society of Toxicology, Lost Pines Molecular Biology Conference, Texas Forum for 

Reproductive Sciences, etc.) and two national meetings (preferably Society of 

Toxicology) by the time they graduate. 


1989, Ph.D. in Toxicology, oral presentation of research results 

Measurement Description:

An updated CV from each trainee is collected from trainees on an annual basis. 




09/30/2007: Over the past five years, x of xx graduating students met or exceeded the 

criterion. 

Furthermore, x% of graduates had presented x or more platform and/or poster reports, 

and on the average they presented x.x reports/student. 


09/30/2007: Trainees and mentors are informed of local and IFT travel finds. 

09/30/2007: The Program Director will emphasize with the mentor and thesis committee 

the importance of presenting research results throughout the course of study. 

2D. DISSERTATION DEFENSE 

Measurement Criterion to be Met: All students will successfully present their 

dissertation research to a thesis committee and the public. 


1989, Ph.D. in Toxicology, publication of research results 


Graduate students nearing completion of the program are required to present and 

defend their research to their thesis committee. If the committee evaluates the thesis 

defense as sufficient to complete the requirements for a Ph.D. in Toxicology, the student 

will then present and defend his/her research in an advertised public seminar. 



Measurement Results 

09/30/2007: Over the past five years, xx Toxicology students were awarded the Ph.D. 

degree. All were judged to have met the requirements for a Ph.D. in Toxicology by their 

thesis committee. All xx students publicly defended their research in a publicized 

seminar. 


Each committee member will fill out the dissertation checklist for Ph.D. students. A 

review of all dissertation checklists will be conducted by the Graduate Program Director 

to identify strengths and deficiencies. These will be discussed with the Department Chair 

to determine appropriate actions for improvement of the Graduate Program. Individual 

plans of action will be developed for students who do not successfully meet the criterion.



3. CAREERS IN SCIENCE 

Students graduating with a Ph.D. in Toxicology will become productive and successful members 

of the scientific community with careers in research, teaching and service. 


All core and elective courses 

3A. RESEARCH-RELATED POSITION (POSTDOCTORAL OR FACULTY LEVEL) IN 

AN ACADEMIC INSTITUTION OR IN INDUSTRY. 


All students who are awarded a Ph.D. in Pharmacology and Toxicology and seek a 

faculty or postdoctoral position in an academic, industrial or government setting will be 

able to obtain such a position. 


1989, Ph.D. in Toxicology, employment in academia, industry or government 


Graduate follow-up data are collected by the IFT administration. 


09/30/2007 Criterion met: Yes 

Measurement Results 

09/30/2007: Over the past five years, x of x graduates were successful in finding 

research-related positions. 

09/30/2007: Over the past year, x of x graduates were successful in finding researchrelated 

positions. 


The IFT Chair will seek support from the Office of Graduate Studies for staff assistance 

to conduct surveys of graduates every three years to determine career satisfaction, 

appropriateness of training for current position, and ways to improve the training 

program. Results will be presented to the IFT Chair, Executive Committee and 

Graduate Mentors for integration into the program. 



4. HIGH QUALITY TRAINING PROGRAM 

The toxicology graduate program will provide high-quality education and research training for 

graduate students. The Ph.D. candidates in Toxicology will create, transmit and apply 

knowledge based in this area to enhance human health. The curriculum has been developed to 

provide broad balanced, comprehensive training in toxicologic principles and effects. The 

research programs of the mentors will be highly regarded by peers. The individualized research 

training experience is directed toward providing the educational and research experience 

expected of scholarly professionals in Toxicology. 


All 

4A. REVIEW OF IFT THROUGH EXIT INTERVIEWS WITH IFT TRAINEES 

FOLLOWING COMPLETION OF THE Ph.D. DEGREE IN TOXICOLOGY 


Designation of the overall training program administered by the IFT as an outstanding 

program, which deserves an international reputation of excellence. 


09/30/2007, Ph.D. in Toxicology, Exit Review of IFT by Students Completing Ph.D. 

Degree in Toxicology


The Toxicology Training program of each trainee completing the Ph.D. degree in 

Toxicology will participate in an exit interview to discuss their experiences in the training 

program. This will be carried out by the IFT Program Assistant. This individual has 

extensive interactions with trainees throughout the program. Interviews carried out by 

the IFT Program Assistant may also minimize concerns about directing criticisms at the 

program and/or individual faculty. However, in the absence of the Program Assistant, 

the interview will be carried out by the IFT Chair. The exit interview will be preceded 

with a brief written survey to provide a general framework for the breadth of input 

requested on the interview. This same survey will be administered to currently enrolled 

trainees and in alternating years. 

Toxicology Program Survey and Exit Interview: 

Rate the following on a scale of 1 to 5 with one = poor, 2 = fair, 3 = average, 4 = 

good, 5 = excellent 

Your knowledge of basic toxicological principles: 

The contribution of the toxicology curriculum to your knowledge: 

The depth and scope of the toxicology curriculum: 

Your preparedness to conduct independent research: 

Your preparedness to write scientific papers and grant proposals: 

Your confidence in your ability to compete for jobs upon graduation: 

The administrative support you receive: 

The opportunities you have to travel to present your research: 

The adequacy of your stipend/compensation: 

The applicability of your coursework to your research: 

The availability of equipment, expertise, and core facilities necessary for your research: 

The quality of the seminar speakers: 

The support you receive from your Mentor: 

The support you receive from your Committee members: 

The likelihood that you would recommend the toxicology program to a prospective 

student: 

Your overall rating of the Toxicology Program: 

Short answer/fill in the blank: 

What was the most helpful course you took? 

What topics, if any, should be addressed more thoroughly in the curriculum? 


November, 2006 

Results reported in Self Study, 2007 


The first survey of resident Toxicology graduate students was conducted in November, 

2006. A similar written survey will be conducted in future even years of all enrolled 

students and will be conducted of all trainees who have completed the Ph.D. degree in 

Toxicology. 

Measurement Actions: Based on the results of the surveys of resident trainees and 

those who have completed the Ph.D. in Toxicology, outcomes will be used to modify any 

and all aspects of the Toxicology Program as needed. The Program Assistant and 

Executive Committee will summarize biannual surveys and exit interviews on a biannual 

basis and develop subsequent actions to improve the program as indicated. Student 

outcomes measured in sections 1 and 2 above will also be evaluated. If necessary, the

Chair and EC will seek assistance from the Office of Graduate Studies and/or the Office 

of the Vice President for Research to identify resources and carry out needed changes 

in the program. 

4B. ACADEMIC REVIEW OF IFT 


Designation of the overall training program administered by the IFT as an outstanding 

program, which deserves an international reputation of excellence. 


1998-2006, Ph.D. in Toxicology, Academic Review of IFT 


Programs are evaluated on a calendar set by the Office of Graduate Studies on the 

basis of faculty productivity (research funding, publications), enrollment and graduation 

trends, student publications, training grants, placement of graduates. 


The last Academic Program Review of the IFT was conducted in 1998 

1998 Criterion met: Yes 


The unanimous consensus of the External Review Committee in 1998 was that the IFT 

has an exceptional toxicology training program. The committee found that the IFT had 

strong direction and leadership and that the administrative structure was effective and 

provided a democratic structure of governance. The faculty was acknowledged for its 

energy and breadth and, through their common research and training activities, a 

collaborative and synergetic presence. Well equipped laboratories and support from 

extramural and intramural sources were considered an asset. The IFT was 

acknowledged for the instrumental role in securing the NIEHS Toxicology Training 

Grant, Superfund Basic Research Program and Center for Environmental and Rural 

Health. The IFT was able to attract an excellent pool of graduate students who 

demonstrated scientific knowledge and the ability to communicate the status of the 

toxicology program. The graduating students were recognized as exceptional by the 

scientific community. Reviewers regarded enrichment activities as additional strengths 

of the IFT training program. 

IFT Academic Program Review for the period of 1998-2006 is scheduled for May 7-9, 

2007 

Measurement Actions: Based on the previous program review, changes in the program 

were made. These are outlined in the self study document. Some of the 

recommendations made to the TAMU administration have been carried out, others have 

not. 

The IFT Chair will work with the Office of the VPR and Office of Graduate Studies to 

implement improvements that can be made with the resources provided. 

Approved by the IFT Executive Committee 

Date: January 9, 2007

Appendix M 

Typical Seminar Speaker Schedules

TEXAS A&M UNIVERSITY 

Interdisciplinary Faculty of Toxicology (IFT) 

4461 TAMU * College Station, TX 77843-4461 * (979) 845-5529 * (979) 862-4929 FAX 

tox@cvm.tamu.edu * http://toxicology.tamu.edu 

Oliver Hankinson, PhD 

Department of Pathological and Laboratory Medicine 

University of California- Los Angeles 

Itinerary 

Sunday, November 19, 2006 

4:25 PM Arrive at College Station airport, American flight 3279. Meet Dr. 

Yanan Tian for dinner and transportation to Vineyard Court 

Suites (confirmation no. 34288) 

Monday, November 20, 2006 

7:30 AM Meet Dr. Yanan Tian for breakfast and transportation to campus Vineyard Ct. lobby 

9:00 AM Meet with the Tian Lab 108 VMRB 

11:00 AM Sign papers and set up presentation with Kim Daniel 210 VMS 

11:30 AM Present seminar entitled “Role of the Aryl Hydrocarbon 

Receptor in Transcription and Cancer” 

210 VMS 

12:30 PM Lunch with graduate students Brian Laffin, Kathy Vanderlaag 

and Elizabeth Wellberg 

2:00 PM Meet with Dr. Weston Porter 406 VMRB 

2:45 PM Meet with Dr. Bob Burghardt B12A VMA 

3:30 PM Unscheduled time to explore the TAMU campus 

5:00 PM Meet Kim Daniel for a ride to Vineyard Court Suites 

6:30 PM Meet Dr. Jane Welsh to go to dinner Vineyard Ct. lobby 

Tuesday, November 21, 2006 

7:50 AM Meet Dr. Weston Porter for breakfast and transportation to 

campus 

Vineyard Ct. lobby 

9:00 AM Meet with Dr. Steve Safe 410 VMRB 

10:30 AM Unscheduled time 

11:30 AM Ride to College Station airport with Brian Laffin for 12:45 PM 

departure on American flight 3260 to DFW. From DFW, 

American flight 2449 to LAX, arriving at 4:20 PM





Curtis Klaassen, PhD 

Department of Pharmacology, Toxicology and Therapeutics 

University of Kansas Medical Center 

Itinerary 

Sunday, February 26, 2006 

4:30 PM Arrive in College Station on Continental flight 9859. Meet Dr. Shashi Ramaiah 

for a ride to Vineyard Court Suites (confirmation no. 31487) 

6:15 PM Meet Dr. Shashi Ramaiah in the Vineyard Court lobby to go to dinner 

6:30 PM Dinner at Café Eccell with Drs. Bob Burghardt, Phil Mirkes, Tim Phillips, Shashi 

Ramaiah and Steve Safe 

Monday, February 27, 2006 

7:30 AM Meet Dr. Yanan Tian in the Vineyard Court lobby to go to breakfast and ride to 

campus 

9:00 AM Meet with the Ramaiah Lab, room 308 Vet. Medical Research Bldg (VMRB) 

10:30 AM Meet with Dr. Steve Safe, room 410 VMRB 

11:15 AM Meet Kim Daniel in room 210 Vet. Medical Sciences Bldg (VMS) to set up 

presentation 

11:30 AM Present seminar entitled “Nuclear Receptor Regulations of Rat Hepatic 

Transporters”, room 210 VMS 

12:30 PM Lunch with Toxicology graduate students Atrayee Banerjee, Xinsheng Gu, 

Tanya Gustafson, Brian Laffin and Elizabeth Wellberg 

2:00 PM Meet with Dr. Alan Parrish, room 364 Reynolds Medical Bldg 

2:45 PM Meet with Dr. Robert Burghardt, room B12 Vet. Med. Administration Bldg. (VMA) 

3:30 PM Meet with Dr. Weston Porter, room 406 VMRB 

4:15 PM Meet with Dr. Tim Phillips, room 404 VMRB 

5:00 PM Meet with Dr. Phil Mirkes and Center for Environmental & Rural Health faculty 

members, room 423 VMRB 

6:30 PM Ride to airport with Dr. Ramaiah for 7:34 PM departure on Continental flight 

9584





Yanming Wang, PhD 

Department of Biochemistry and Molecular Biology 

Penn State University 

Itinerary 

Sunday, December 4, 2005 

8:25 PM Arrive at College Station airport American Airlines flight 3241. Meet Dr. Yanan Tian for a ride to 

Vineyard Court Suites, confirmation number 30253 

Monday, December 5, 2005 

7:30 AM Meet Dr. Yanan Tian in Vineyard Court lobby to go to breakfast and ride to campus 

9:00 AM Meet with Dr. Tian’s Lab, room 108 Vet. Medical Research Bldg (VMRB) 

11:15 AM Meet Kim Daniel in room 210 Vet. Medical Sciences Bldg (VMS) to set up presentation 

11:30 AM Present seminar entitled “Histone Methylation in Gene Expression and Cancer Epigenetics”, 

room 210 VMS 

12:30 PM Lunch with graduate students Timothy Yu and Ying Xie 

2:00 PM Meet with Dr. Weston Porter, room 406 VMRB 

2:45 PM Meet with the Porter Lab, room 228 VMRB 

3:30 PM Meet with Dr. Steve Safe, room 410 VMRB 

4:10 PM Meet with Dr. Duan Liu and graduate student Xinsheng Gu, room 124 VMRB 

4:50 PM Ride to Vineyard Court with Kim Daniel 

6:30 PM Meet graduate students Tanya Gustafson and Elizabeth Wellberg in Vineyard Court lobby to go to 

dinner 

Tuesday, December 6, 2005 

Continental breakfast at Vineyard Court 

8:15 AM Meet graduate student Timothy Yu in Vineyard Court lobby for a ride to campus 

8:30 AM Meet Dr. Mike Kladde, room 430A Biochemistry/Biophysics Bldg 

9:15 AM Meet with Dr. Nancy Ing, room 410D Kleberg Center 

10:00 AM Meet Dr. Glen Laine, room 332 Vet. Medical Administration Bldg (VMA) 

11:00 AM Ride to College Station airport with Kim Daniel for 12:17 PM departure on American Airlines flight 

3260

Appendix N 

Graduate Student Survey of the IFT

TO: 

FROM: 

SUBJECT: 

Toxicology and Affiliated Students 

Brian Laffin 

Toxicology Student Representative 

Fall 2006 Toxicology Student Survey 

The Toxicology Executive Committee (EC) has charged me with conducting a survey of 

toxicology graduate students and other graduate students closely affiliated with the Toxicology 

Program in order to receive student input on the program for the external review. This will be 

very brief, and for toxicology majors participation is mandatory. For those of you who are not 

toxicology majors but interact with the program on a regular basis, your participation is strongly 

encouraged and you may simply not answer questions that are not relevant to you or for which 

you do not have an answer. 

All answers will be kept strictly confidential, meaning that you and I are the only ones who will 

ever know what you answered. The answers will be compiled as scores for the purposes of the 

review and to provide the executive committee with information to improve the program. 

Answers to the 2 brief short answer questions will be presented to the EC without names 

attached and in random order. Additionally, after the survey has been conducted a meeting 

between all of the students and the EC will be scheduled to address any concerns or ideas that 

may not be covered under this survey. The purpose of this survey and the meeting is to improve 

the program for current and future students, so don't hold back with any concerns you may 

have. As student representative to the EC, my job is to represent and communicate your 

concerns to the EC. If they didn't want to hear student concerns they certainly wouldn't have 

asked me to do this job. If you have any questions feel free to e-mail me or call me at 5-1473, or 

even stop by my office in room 228 of the research tower. 

Here is the Survey. Type your answer in the space below the question and e-mail it back to me. 

Rate the following on a scale of 1 to 5, with 1 = poor, 2 = fair, 3 = average, 4 = good, 5 = 

excellent: 

A. Your knowledge of basic toxicological principles 

B. The contribution of the toxicology curriculum to your knowledge 

C. The depth and scope of the toxicology curriculum 

D. Your preparedness to conduct independent research 

E. Your preparedness to write scientific papers and grant proposals 

F. Your confidence in your ability to compete for jobs upon graduation 

G. The administrative support you receive 

H. The opportunities you have to travel to present your research 

I. The adequacy of your stipend/compensation

J. The applicability of your coursework to your research 

K. The availability of equipment, expertise, and core facilities necessary for your research 

L. The quality of the seminar speakers 

M. The support you receive from your committee and advisor(s) 

N. The likelihood that you would recommend the Toxicology Program to a prospective 

student 

O. Your overall rating of the Toxicology Program 

Short answer/fill in the blank: 

P. What was the most helpful course you took? 

Q. What topics, if any, should be addressed more thoroughly in the curriculum?

Appendix O 

IFT Faculty Roster

IFT Faculty Roster 

Name Department College System Part 

Abbott, Louise C. Vet. Integrative Biosci. CVM TAMU 

Allred, Clinton D. Nutrition and Food Science COALS TAMU 

Autenrieth, Robin l. Civil Engineering Engineering TAMU 

Ball, Judith M. Vet. Pathobiology CVM TAMU 

Barr, A. Catherine Texas Vet Med Diag Lab CVM TAMU 

Bernstein, Lori R. Molec. & Cellular Med. Medicine TAMHSC 

Bratton, Gerald R. Vet. Integrative Biosci. CVM TAMU 

Burghardt, Robert C. * Vet. Integrative Biosci. CVM TAMU 

Busbee, David L. Vet. Integrative Biosci. CVM TAMU 

Calvin, James A. Assoc VP Res/Statistics Admin/Science TAMU 

Carroll, Raymond J. Statistics Science TAMU 

Chapkin, Robert S. Nutrition and Food Science COALS TAMU 

Dees, W. Les Vet. Integrative Biosci. CVM TAMU 

Donnelly, K.C. Env. & Occup. Health SRPH TAMHSC 

Fackler, John P. Chemistry Science TAMU 

Finnell, Richard H. IBT/Vet. Integrative Biosci. IBT / CVM TAMHSC / TAMU 

Harvey, Roger B. USDA/Vet. Integrative Bio. CVM TAMU 

Johnson, Larry Vet. Integrative Biosci. CVM TAMU 

Kier, Ann B. Vet. Pathobiology CVM TAMU 

Ko, Gladys Y.L. Vet. Integrative Biosci. CVM TAMU 

Miranda, Rajesh C. Neurosci. Exp. Therap. Medicine TAMHSC 

Mirkes, Philip E. * Vet. Physiol. Pharm. CVM TAMU 

Mora, Miguel Wildlife Fisheries Sci. COALS TAMU 

Nation, Jack R. Psychology Liberal Arts TAMU 

Parrish, Alan R. Syst. Biol. Transl. Med. Medicine TAMHSC 

Phillips, Timothy D. * Vet. Integrative Biosci. CVM TAMU 

Pietrantonio, Patricia V. Entomology COALS TAMU 

Pillai, Suresh Poultry Science COALS TAMU 

Porter, Weston W. * Vet. Integrative Biosci. CVM TAMU 

Ramaiah, Shashi K. * Vet. Pathobiology CVM TAMU 

Raushel, Frank M. Chemistry Science TAMU 

Reagor, John C. Texas Vet Med Diag Lab CVM TAMU 

Russell, Leon H. Vet. Integrative Biosci. CVM TAMU 

Safe, Stephen H. * Vet. Physiol. Pharm./IBT CVM / IBT TAMU / TAMHSC 

Schroeder, Friedhelm Vet. Physiol. Pharm. CVM TAMU 

Senseman, Scott A. Soil & Crop Sciences COALS TAMU 

Sherman, Michael Statistics Science TAMU 

Simanek, Eric Chemistry Science TAMU 

Spencer, Thomas E. Animal Science COALS TAMU 

Spiegelman, Cliff Statistics Science TAMU 

Stallone, John N. Vet. Physiol. Pharm. CVM TAMU 

Stoica, Gheorghe Vet. Pathobiology CVM TAMU 

Thompson, James A. Vet. Large Anim. & Surg. CVM TAMU 

Tian, Yanan * Vet. Physiol. Pharm. CVM TAMU 

Tiffany-Castiglioni, Evelyn Vet. Integrative Biosci. CVM TAMU 

Turner, Nancy D. Nutrition and Food Science COALS TAMU 

Walker, Cheryl L. Vet. Physiol. Pharm -Adjunct CVM TAMU 

Wang, Naisyin Statistics Science TAMU 

Wild, James R. Biochem. & Biophys. COALS TAMU 

Wilson, Cody L. EOHS-Adjunct SRPH TAMHSC 

Wilson, Emily Syst. Biol. Transl. Med. Medicine TAMHSC 

* Members of the IFT Executive Committee

Appendix P 

Courses Taught by IFT Faculty

Courses Taught by IFT Faculty 

IFT members teach courses throughout TAMU and TAMHSC. Bold type indicates Core Courses for 

Toxicology graduate students. 

Course Course Title SCH Instructor 

AGRO650 

Mode of Action and Environmental Fate of 3 S Senseman 

Herbicides 

ANSC 630 Reproductive Biology I 4 TE Spencer 

ANSC 631 Reproductive Biology II 4 TE Spencer 

BIMS 101 Introduction to Biomedical Science 1 LC Abbott 

BIOL 601 Biological Clock 3 GYP Ko 

BIOL/PSYC/VIBS 689 Principles of Neuroscience 3 GYP Ko 

BIOT 603 Applied Principles of Biotechnology 4 SD Pillai 

BIOT 681 Biotechnology Seminar 1 SD Pillai 

CHEM 101 Fundamentals of Chemistry I 4 E Simanek 

CHEM 102 Fundamentals of Chemistry II 4 E Simanek 

CHEM 103 Structure and Bonding 3 JP Fackler 

CHEM 242 Elementary Organic Chemistry Lab 1 E Simanek 

CHEM 462 Advanced Inorganic Chemistry 3 JP Fackler 

CHEM 672 Bioorganic Reaction Mechanisms 3 FM Raushel 

CHEM 681 Graduate Student Seminar 1 FM Raushel 

CVEN 301 Environmental Engineering 3 RL Autenrieth 

CVEN 610 Environmental Risk Assessment 3 RL Autenrieth 

ENTO 615 Insect Physiology 3 PV Pietrantonio 

ENTO 619 Insect Toxicology 4 PV Pietrantonio 

FSTC 481 Food Science & Technology Seminar 1 SD Pillai 

FSTC/AGRO/POSC/ Molecular Methods for Microbial 

3 SD Pillai 

VTMI 619 

Characterization 

FSTC/POSC 689 Microbiology of Food Irradiation 3 SD Pillai 

GENE 302 Principles of Genetics 4 JR Wild 

GENE420 Bioethics 3 JR Wild 

GENE420H Honors Studies in Bioethics 3 JR Wild 

MPHY 601 Methods is Cell Physiology 4 E Wilson 

MPHY 604 Advanced Cardiovascular Biology I 4 E Wilson 

NUTR 203 Scientific Principles of Human Nutrition 3 RS Chapkin 

NUTR 481 Seminar 1 ND Turner 

NUTR 642 Nutritional Biochemistry II 3 RS Chapkin 

PSYC 107 Introduction to Psychology 3 JR Nation 

PSYC 340 Psychology of Learning 3 JR Nation 

STAT 601 Statistical Analysis 4 M Sherman 

STAT 607 Sampling 3 M Sherman 

STAT 616 Multivariate Analysis 3 M Sherman 

STAT 636 Methods in Multivariate Analysis 3 C Spiegelman 

STAT 642 Statistical Methods II 3 C Spiegelman 

STAT 643 Biostatistics I 3 N Wang 

STAT 647 Spatial Statistics 3 M Sherman 

STAT 651 Statistics in Research I 3 N Wang 

STAT 681 Statistics Seminar 1 RJ Carroll 

VIBS 404 Food Toxicology 3 LH Russell

VIBS 404H Honors Food Toxicology and Safety 3 TD Phillips 

VIBS 432 Public Health Practices 3 KC Donnelly 

VIBS 450 Comparative Mammalian Neurology 3 GPY Ko 

VIBS/PHEO 605 Chemical Hazard Assessment 3 KC Donnelly 

VIBS 607 Applied Epidemiology 4 LH Russell 

VIBS 612 Mammalian Embryology 4 LC Abbott 

VIBS/PHEO 614 Biodegradation & Bioremediation 3 KC Donnelly 

VIBS 617 Advanced Cell Biology I 1 RC Burghardt 

VIBS 617 Advanced Cell Biology II 1 PE Mirkes 

VIBS 617 Advanced Cell Biology III 1 WW Porter 

VIBS 618 Food Toxicology 3 TD Phillips 

VIBS 619 Food Toxicology II 3 TD Phillips 

VIBS 633 Animal Diseases in Comparative Medicine 3 LH Russell 

VIBS/PHEO 670 Basic Environmental Toxicology 3 KC Donnelly 

VIBS 911 Microscopic Anatomy I 4 LC Abbott 

VIBS 913 Microscopic Anatomy II 4 LC Abbott 

VIBS 948 Anatomy Elective 3 LH Russell 

VLCS 931 Bovine Reproduction 1 JA Thompson 

VMID 686 Scientific Ethics 1 L Johnson 

VPAT 642 Metabolic Disease 2 SK Ramaiah 

VPAT 681 Clinical pathology seminar 1 SK Ramaiah 

VPAT 681 Histopathology Seminar 1 SK Ramaiah 

VTMI 601 Fundamentals of Pathobiology 5 JM Ball 

VTMI 647 Virology 4 JM Ball 

VTMI 689 Protein Transport in Mammalian Cells 3 JM Ball 

VTPB 923 Pathology II 3 SK Ramaiah 

VTPP 673 Metabolic & Detoxication Mechanisms 3 SH Safe 

VTPP 676 Genetic and Molecular Toxicology 3 Y Tian 

VTPP 681 Toxicology Seminar 1 SH Safe 

VTPP 689 Special Topics in Bioinformatics 3 F Schroeder 

VTPP 910 Veterinary Physiology I 6 JN Stallone 

VTPP 912 Veterinary Physiology II 6 JN Stallone

Appendix Q 

Research Support of IFT

Research Grant Support of IFT Faculty 

Active Support 

Funding 

Institution 

DOD Breast 


Program 

Grant No. PI Title IFT Collaborators 

W81XWH-04-1- 

0532 

Allred 

Defining the Molecular 

Actions of Dietary Fatty 

Acids in Breast Cancer: 

Selective Modulation of 

Peroxisome Proliferator- 

Activated Receptor γ 

USDA 00-35203-9137 Bazer Roles of Fibroblast Growth 

Factor-7 in Uterine Biology 

and Pregnancy in Pigs. 

NIH/NICHD 2 R01 HD32534 Bazer Ovine Interferon-Tau 

Regulates Uterine Hormone 

Receptors 

NIH/NIGMS 

NCRR 

NIH/NCI 

P20 

GM072041-01 

1S10RR22532- 

0 

1 P50 

CA098258-02 

Burgess 

Burghardt 

Burke 

Fluorescence Probes for 

Multiplexed Intracellular 

Imaging 

Acquisition of a 

Confocal/Multiphoton 

Microscopy System 

MD Anderson Cancer 

Center Gynecologic SPORE 

for Uterine Cancer 

NSF/DMS 216275 Calvin MRI: Development of a High 

Density, High Performance 

Beowulf Cluster 


Excellence 

NIH 

U50/CCU613- 

232 

2R37 

CA057030-17 

Canfield 

Carroll 

National Birth Defects 

Prevention Study-Texas 


Nutrition, and Breast/Colon 

Cancer 

NIH R25 CA 90301 Carroll Training Program in 

Biostatistics, Bioinformatics 

Total 

Direct 

Award 

Annual 

Direct 

Award 

Funding 

Period 

$299,398 4/1/04 – 

3/31/07 

Spencer $633,000 $190,000 5/1/05- 

4/30/08 

Spencer $1,309,500 $261,900 03/01/01- 

02/28/07 

Schroeder, Kier $424,036 $75,000 8/01/04- 

8/31/08 

$777,371 6/01/06- 

5/30/07 

Walker 9/15/03- 

9/14/08 

$405,202 $81,040 8/1/02- 

7/31/07 

Finnell $844,725 $168,945 10/1/02- 

9/30/07 

$1,125,000 $140,625 9/01/05- 

8/31/08 

Chapkin $500,000 $166,667 12/1/05- 

11/30/08

and Nutrition 

NIH/NCI R25T CA90301 Carroll Nutrition, Biostatistics and 

Bioinformatics 

AICR 05A081 Chapkin Use of novel genetic mouse 

models to investigate the 

health benefits of folate in 

colon cancer. 

NIH R01 CA59034 Chapkin Colonic cytokinetics and cell 

NIH-NINDS MSM 

R01-NS54252- 

01 

Choe 

signaling: dietary effect 

Multiscale imaging, 

analysis, and integration of 

brain networks 

NIH R01 HL072989 Davis Regulation of vascular tone 

and calcium channels by 

integrins 

NIH R01 HL071796 Davis Regulation of arteriolar tone 

and K channels by integrins 

NIH/NIAAA R01-AA07216- Dees Neuroendocrine Effects of 

19 

Alcohol on Puberty 

NIH/NHLBI 

1 R01 HL- Delp 

Aging, Estrogen, and 

077224-01 

Coronary Endothelial 

Wilson, E. $34,000 $8,500 8/1/03- 

7/31/07 

03/01/07- 

02/28/12 

Stallone $20,403 $6,801 4/1/05- 

3/31/08 

Function 

Donnelly Public Health Traineeship $10,365 $2,591 7/1/02- 

6/30/10 

Donnelly Border Environmental 

$31,271 $10,424 9/1/05- 

Health Coordination 

8/31/08 

$371,681 $92,920 1/31/03- 

1/31/07 

DHHS-HRSA 5 A03 HP 

01192-03-00 

DHHS-HRSA 6U55RH06350- 

01-02 

USEPA RD 83068401-0 Donnelly Issues in Human Health 

Assessment: Novel 

Mechanistic Approaches in 

Human Health 

Turner $2,469,800 $493,960 8/1/06- 

7/31/11 

Finnell $150,000 $75,000 8/1/05- 

7/31/07 

$1,000,000 $200,000 5/1/03 - 

6/30/08 

Abbott $966,000 $322,000 9/1/05- 

7/31/08 

Wilson, E. $34,000 $8,500 4/1/03- 

3/31/07 

USEPA X4-96608801-0 Donnelly Border 2012-Childhood 

Exposure & Susceptibility to 

Pesticides in Texas/Mexico 

Border Region 

$26,265 $26,265 10/1/05- 

1/31/07 

Welch 

N/A Fackler New Gold Complexes with 

$210,000 $70,000 2004-2007 

Foundation 

Nitrogen Ligands 

NIH/NIDCR 1R01DE016315 

-01A1 

Finnell Genetic regulation of folate 

responsive birth defects. 

$1,250,000 $250,000 8/1/05- 

4/30/10 

NIH 5 K25 Gallegos Cholesterol ester Kier (mentor) 8/1/03-

Raushel $1,600,000 $80,000 7/1/04- 

6/30/09 

Abbott $1,000,000 $200,000 9/1/03 - 

8/31/08 

Schroeder, Kier $120,000 $40,000 4/1/04- 

3/31/07 

DK062812-03 

targeting in fatty acid 

binding protein geneablated 

mice 

NIH P01 GM 71790 Gerlt Deciphering Enzyme 

Specificity 

NIH-NIA 

RO1- Griffith Physiology of Cholinergic 

NIH 

AG007805-9 

F32 

DK066732-02 

Hostetler 

Basal Forebrain Neurons 

“Intracellular trafficking of 

long chain fatty acyl 

CoAs 

NIH DK077573 Hostetler The role of long chain acyl- 

CoAs in nuclear receptor 

regulation 

NIH-NHLBI 

1R01HL080415 

-01 

Humphrey 

Ex vivo delineation of 

mechanisms of cerebral 

vasospasm 

NIH Johnson Enhancement of K-12 

Science Education – 


NIH 

R01-AI51593- 

02 

Leibowitz 

Interaction of MHV RNA 

with mtHSP70 and m- 

aconitase 

NSBRI NPFR00402 Lupton Nutritional Countermeasures 

to Radiation- 

Enhanced Colon Cancer 

NSBRI EO0064 Lupton Ph.D. Training Program in 

Critical Areas of Space Life 

Sciences 

NIH/NCI 

5 R01 

CA82907-04 

Lupton Diet, Apoptosis and Colon 


NIH R01 AI15495 McMurray Dietary deficiencies and 

tuberculosis vaccine 

efficacy 

NIH/NIAID T32 AI052072 McMurray Mechanistic studies at the 

host-pathogen interface 

NIH NS041548 Miranda Learning within the spinal 

cord: clinical implications 

NIH/NIAAA AA13440 Miranda Fetal Alcohol Exposure and 

neurodevelopment 

7/31/08 

Schroeder, Kier 

(co-mentors) 

$671,219 $78,115 2006-2011 

Wilson, E. $1,235,000 $308,750 4/1/05- 

3/31/09 

Wild 9/1/04 – 

8/31/08 

Abbott 9/1/03 - 

8/31/08 


Carroll 

$1,329,516 $235,312 10/1/04- 

9/30/08 

Turner $72,690 $48,460 7/1/06- 

6/31/12 


Carroll 

$900,000 $225,000 2/1/01- 

1/31/07 

Chapkin $1,000,000 $200,000 2/1/05 - 

1/31/10 

Ball $797,684 $159,537 9/1/03- 

8/30/08 

$373,705 $258,138 9/1/05- 

8/31/10 

Sherman $393,750 $175,000 9/1/03 - 

8/31/08

NIH/NIEHS P30 ES09106 Mirkes Center for Environmental 


NIH/NIEHS R01 ES07026 Mirkes Bcl-2, ROS and Cell Death 

in Developmental Toxicity 

NIH 

T32 MH65728- 

Texas Consortium Program 

01 

in Behavioral Neuroscience 

NIH/NIA 

1 R21 Parrish Age-Dependent Loss of N- 

AG024179 

Cadherin in Rat Proximal 

Texas 

Department of 

Health 

Engelhard 

Chemical 

Corporation 

Engelhard 

Chemical 

Corporation 

USAID-ALO 

TAMU-Fire Ant 

Legislative 

Initiative 

IAC 1459- 

32790 

TAES 402905- 

98 

TAES License 

Agreement 

USAID (Peanut 

CRSP) RF 

453421 

Phillips 

Phillips 

Phillips 

Phillips 

Pietrantonio 

/ Vinson 

Tubules 

Methods for detecting 

aflatoxin M1 in milk and 

dairy products 

Development of 

enterosorbents for 

mycotoxins in animal feeds 

Method for inactivating 

mycotoxins in the 

gastrointestinal tract of 

animals 

Sustainable enterosorbent 

strategies for the protection 

of African populations from 

aflatoxin 

Developing the concept of 

reproductive control as a 

method to reduce the 

Abbott, Ball, 

Bernstein, 

Burghardt, 

Busbee, Calvin, 

Carroll, Chapkin, 

Dees, Donnelly, 

Finnell, Miranda, 

Parrish, Phillips, 

Porter, Ramaiah, 

Safe, Sherman, 

Spencer, 

Spiegelman, 

Tian, Tiffany- 

Castiglioni, 

Turner, Wang, 

Wild, E. Wilson 

$4,980,523 $1,000,00 

0 

4/1/02- 

3/31/07 

05/01/04- 

04/30/08 

Nation $2,781,118 2002-2007 

Burghardt $200,000 $100,000 9/01/03 - 

5/31/07 

Recurrent 

Funding 

09/01/98- 

10/31/07 

$54,086 $20,252 Recurrent 

Funding 

$583,622 $54,982 7/1/02- 

6/30/07 

2006-2007

Imported Fire ant 

populations 

NASA Pillai Electron beam sterilization 

of spacecraft components 

NIH 

1R01CA111551 

-01A1 

Porter 

Singleminded-2 in 

Mammary Gland and Breast 

Cancer 

NIH/NIAAA F31AA015232 Prock The Effects of Alcohol on 

Cell Fate Heterogeneity 

NIH R01 GM 68550 Raushel Enzymatic Detoxification of 


Welch 

A-840 Raushel Enzyme Reaction 

Foundation 

Mechanisms 

NIH/NIEHS R01-ES04176 Safe Effects of 2,3,7,8-TCDD on 


NIH/NIEHS R01-ES09253 Safe Mechanism of Growth 

Factor-Estrogen Receptor 

Crosstalk 

NIH/NIEHS T32-ES07273 Safe Toxicology of Environmental 

Contaminants 

NIH/NIEHS P42-ES04917 Safe Procedures to Assess the 

Hazard of a Superfund Site 

(Total Program Project 

Grant) 

NIH R01-CA104116 Safe Coactivation of Estrogen 

Rreceptor α/Sp1 

NCI R01-CA112337 Safe Colon Cancer Inhibition by a 

Class of PPARγ Agonists 

NCI R01-CA108718 Safe Inhibition of Pancreatic 

NIH/NIGMS 

R01 

GM31651-23 

Schroeder 

Cancer by PPARγ Agonists 

Asymmetric Distribution 

of Cholesterol in 

Membranes 

$900,000 $300,000 9/1/04- 

8/31/07 

$822,000 $158,000 7/1/05- 

4/3010 

Miranda (mentor) 5/1/05- 

4/31/07 

$1,190,000 7/1/03- 

6/30/07 

$150,000 $50,000 6/1/05- 

5/31/08 

Burghardt $750,000 $150,000 1/1/02- 

12/31/07 

Burghardt $750,000 $150,000 9/1/01 - 

8/31/07 

Burghardt, 


Johnson, 

Phillips, 

Castiglioni, Wild 

Burghardt, 


Phillips 

$1,100,000 $133,554 7/01/97- 

6/30/07 

$3,163,000 $1,054,33 

3 

4/1/05- 

3/31/08 

Burghardt $450,000 $150,000 4/1/04- 

3/31/07 

Burghardt, Porter $875,000 $175,000 1/1/05- 

12/31/09 

Porter $875,000 $175,000 11/1/04- 

10/31/09 

Kier 

NIH DK 41402 Schroeder Fatty Acid Binding 

Kier $1,250,000 $250,000 2006-2011 

Protein-Ligand Specificity 

USDA-CSREES- 2003-35212- Scott Transmission Dynamics of Harvey 9/1/03-

NRI 13298 Antimicrobial Resistance in 

Integrated Animal and 

Human Populations 


Excellence 

NIH/NINDS 

NIH/NHLBI 

U59/CCU91324 

1 

R01 NS050249- 

01 

R01 HL085859- 

01 

Shaw 

Shaw 

Shaw 

Genetic and Environmental 

Risks of Common Birth 

Defects 

Gene-nutrient etiologies of 

neural tube defects 

Gene and Nutrient 

Etiologies of Human Heart 

Defects. 

NSF GK12 Simanek Building Understanding 

through Research 

Partnerships 

NSF-CCLI Simanek Anchoring Organic 

Chemistry in Context 

USDA NRI 2005- Spencer Biological Functions of 

01476 

Galectin-15 in the Ovine 

Texas 

Transportation 

Institute 

NIH/NHLBI 

1R01 HL- 

080402-01A1 

8/31/07 

Finnell $1,124,335 $224,867 10/1/02- 

9/30/07 


8/31/10 


9/30/09 

$1,904,916 2/2/06- 

2/1/09 

$149,998 $49,999 1/27/06- 

1/14/09 

Burghardt $275,000 $91,667 07/01/05- 

06/30/08 

Uterus 

Spiegelman Textbook composition grant $45,000 

Stallone 

Nongenomic Mechanisms of 

Androgens in the Vascular 

Wall 

NIH R03CA119696 Thompson The Joint Risks of 

Hazardous Air Pollutants 

Among Childhood Cancer 

Histotypes 

NIEHS 

5R01ES009859 

-07 

Tian 

Regulation of cyp1a1 by Ah 

receptor and NFkB 

interaction 

USDA/ARS 58-5430-5-339 Turner Sorghum Bioactive 

Constituents as Colon 

Cancer Chemoprotectants 

AICR 05B094 Vanamala Fish oil and pectin 

enhances apoptosis in 

colonocytes via inhibition of 

PGE2 and PPAR delta 

signaling and promotion of 

Schroeder $1,140,740 $285,185 4/1/06- 

3/31/10 

$145,500 

$950,000 $190,000 2/1/00- 

7/31/08 

9/1/05 – 

6/30/07 

Turner 1/2/06 – 

1/1/08

death receptor pathway. 

NIH/NCI 

5 R01 

CA63613-11 

Walker Genetic Determinants of Rat 

Renal Carcinogenesis 

NIH/NIEHS 

5 R01 Walker Environmental Estrogens 

ES008263-12 

and Uterine Leiomyoma 

NIH/NIEHS R01 HD046282- Walker Uterine Leiomyoma: 

04 

Molecular Etiology 

NCI Wang, LH Non-invasive optical 

detection of skin cancer 

NIH R01 CA74552 Wang, N. Measurement Error, Missing 

Data and Semiparametrics 

Office of Naval N00014-02-1- Wild 

Summer Undergraduate 

Research 

0536 (Co-PI) Research Experiences— 

Multi-University Research 

Consortium: Research 

Leadership for the 21 st 

Century 

NIH Wild 

Enhancement of K-12 

(Co-PI) Science Education – 



Wilson, E. Matrix-dependent 

Association 

modulation of SRFmediated 

transcription by 

cyclic stretch in vascular 

smooth muscle 




NIH AI044594 Zhu Fatty Acid Biosynthesis in 

Cryptosporidium parvum 

6/03/94- 

3/31/08 

8/1/96- 

3/31/07 

9/24/03- 

7/31/07 

Wang, N. $1,800,000 $360,000 9/01/04- 

8/31/09 

Chapkin $631,000 $315,500 8/1/05- 

7/31/07 

10/1/03 - 

09/1/07 

9/04 – 

8/08 

$130,000 $65,000 7/01/05- 

6/30/07 

Spencer $230,850 $76,000 4/1/98- 

3/31/07 

Schroeder $1,125,000 $225,000 2006-2011

Recently Completed Support 

Funding 

Institution 

Grant No. PI Title IFT Collaborators 

Total 

Direct 

Award 

Annual 

Direct 

Award 

Funding 

Period 

NIEHS 

P30-EF09106 

TAMU 

Abbott Pilot Project: Molecular mecha 

of methylmercury toxicity 

6/1/03- 

7/31/05 

NIH N/A Allred Loan Repayment Program $17,988 10/1/04- 

11/1/06 

NIH/NICHD T32 HD07436- 

10 

Allred Training Grant in 

Reproductive Sciences 

4/1/03 – 

3/31/04 

Postdoctoral Fellowship 

USDA/CSREES TEX08565 Ball Gastroenteritis induced by 

viral enterotoxins 

USDA/CSREES TEX08971 Ball (Co-PI) EIAV modulatin of cytokine 

responses and generation 

of critical equine reagents 

5/22/98- 

5/21/04 

6/23/03- 

9/30/05 

USDA/CSREES TEX08974 Ball (Co-PI) Genetic diversity of equine 

infectious anemia virus 

USDA/CSREES TEX09096 Ball/Payne Effects of equine infectious 

anemia virus on expression 

of cytokines and 

chemokines in equine cells 

USDA/CSREE TEX09104 Ball Role of plasma membrane 

S 

microdomains in EIAV 

signaling events: A new 

NIH/NIGMS 

Colgate- 

Palmolive Grants 

for Alternatives 

Research 

Texas A&M 

Univeristy 

NIEHS, Center 

for Environmental 

5R01GM06232 

6-05 

Ball 

target of intervention 

Transport and lipid 

interactions of a novel 

enterotoxin 

N/A Barhoumi Early Toxicity Screening for 



N/A Bazer Training Grant in 

Reproductive Biology 

N/A Bernstein Pilot Project: YB-1, a new 

AP-1 DNA binding 

5/01/03- 

9/30/05 

5/5/05- 

9/30/06 

7/14/05- 

9/30/06 

Schroeder $1,135,860 $227,172 6/1/01- 

5/31/06 

Castiglioni $39,326 $39,326 1/1/06- 

12/31/06 

Burghardt, Dees, 

Safe, Spencer 

$198,373 $99,187 10/1/05- 

9/30/06 

4/01/05- 

3/31/06


transrepressor 

Elsa U. Pardee 

Foundati 

on 

N/A Bernstein Nucleolin and YB-1: New 


transrepressors 

Max and Victoria N/A Bernstein Nucleolin and YB-1: New 

Dreyfus 


Foundation 

transrepressors 

NIH First 

R29 CA73783- Bernstein Cloning of MAP kinaserelated 

Independent 

02 

proteins that bind 

Research 

AP-1 in vivo. 

Support and 

Transition Award 

Max and Victoria N/A Bernstein YB-1, a new AP-1 DNA 

Dreyfus 


Foundation 

TAMHSC N/A Bernstein YB-1, a new AP-1 DNA 


TAMU LSTF Brooks Health Observing Systems 

Program 

WMA Foundation N/A Busbee Methods to Study 

Chemicals that Alter Gene 

Expression 

NSF EEC-0227681 Butler-Purry Research Experience for 

Teachers (E 3 ) 

NCI 

R01 CA092670- Carozza Risk of Childhood Cancers 

05 

Associated with Agricultural 

Exponent (DOD) 

Subcontract to 

TAMU 

USDA CSREES 2003- 

00818 

USDA Special 

Grant-Designing 

Foods for Health 

CSREES 2005- 

30741 

Co-PIs - 

Castiglioni 

and Bratton 

Chapkin 

Chapkin 

Pesticide Use 

Proposal to Develop 

Extraction Tests for 

Determining Bioavailability 

of Metals in Soil. 

Nutritional modulation of 

immunity: Regulation of 

Th1/Th2 responses. 

Antiinflammatory effects of 

omega-3 fatty acids: 

Potential enhancement by 

citrus flavonoids 

01/04- 

01/06 

06/04- 

07/05 

7/1/97- 

6/30/04 

$15,000 $15,000 6/1/05- 

5/31/06 

$15,000 $15,000 2/1/05- 

1/31/06 

Autenrieth 2003- 

2006 

7/1/01- 

6/30/06 


2005 

Sherman 9/3/01- 

2/28/06 

4/01 – 

3/04 

$225,000 $75,000 7/1/03 - 

6/30/06 

$49,000 $49,000 10/1/05- 

9/30/06 

Scott & White N/A Chapkin Non-invasive detection of $40,000 $40,000 5/1/05-

Clinic TAMHSC 

human epithelial cell gene 

expression profiles using 

exfoliated colonocytes: 

development of robust 

classifiers for colon cancer 

and pre-cancerous 

inflammatory bowel disease. 

NIH Subcontract 26XS039A Chapkin The effects of high legume 

low glycemic index on 

insulin resistance and 

inflammation in patients at 

high risk for colorectal 

adenoma recurrence. 

NIH NS39899 Chen Nicotine and Brain 

Development 

NIH R01 HL071796 Davis Mechanism and function of 

the vascular myogenic 

response 

NIH/NIEHS R01 ES013143 Dees Actions of Manganese on 


NIH/NIEHS 

1 R01 

ES09627-04 

Dees 

Development 

Effects of Lead (Pb) on 


Development 

NSF NA Delp Circulatory Remodeling with 

Simulated Microgravity 

NIH/NIEHS 

2 P30 DiGiovanni Mechanisms and Prevention 

ES07784-10 

of Environmental Disease 

DHHS/PHS/HRS 232-02-0001 Donnelly Safe Drinking Water 

A 

Demonstration Project for 

Hidalgo County, Texas 

USEPA X4-97672601-0 Donnelly Measurement and 

Reduction of Childhood 

Exposure to Pesticides: 

Texas/Mexico Border 

USEPA 4D-5646-NAEX Donnelly Children’s 

Neurodevelopmental 

Assessment Project 

4/30/06 

$100,000 $100,000 10/1/05- 

9/30/06 


3/31/05 

Wilson E 05/01/98- 

04/30/04 

$672,000 $168,000 8/15/01- 

7/31/06 

Bratton 3/01/99- 

2/28/04 

Wilson E 04/01/01- 

03/31/04 

Walker 04/01/01- 

03/31/06 

6/03/02- 

1/31/05 

10/01/04- 

9/30/05 

CDC 200-2005-M- Donnelly Longitudinal Variability in $25,000 $25,000 6/30/05- 

2/5/04- 

9/3/05

12814 Urinary Pesticide 

Metabolites Among Children 

USEPA Dozier Use of integrated weed 

management strategies and 

computer technologies to 

reduce environmental 

impact in corn and cotton 

production 

Welch 

Fackler Metal Sulfur Complexes of 

Foundation 

Group 11 Elements 

NIDCR DE13613-05 Finnell Folate receptors and 

craniofacial malformations 

NSF-NTE Ford Engineering on 




Separations 

USGS Goebel Novel polymeric water 

treatment for in situ removal 

of organic contaminants for 

water bodies. 

NINDS NS041548 Grau Learning Within the Spinal 

Cord: Clinical Implications 

Super Jake 

06-60043 Harris Evaluation of Citrus 

Foundation 

Limonoids Against 

Neuroblastomas-Animal 

studies 

NSF EEC-0244082 Honeycutt Multi-Disciplinary Training in 

Solving Complex 

Environmental Problems 

NSF DEB-0203992 Honeycutt UMEB: Undergraduate 

Training in Ecological and 

Evolutionary Approaches to 

Complex Environmental 

Problems 

NIH R01 HL-64372 Humphrey Histo-mechanics & Biology 

of Remodeling of 

Hypertension 

NIH/NIA 

1 R01 AG- 

19327-01 

Knowlton 

Aging, Estrogen and Heat 

Shock Proteins in 

7/7/06 

Senseman 2003- 

2005 

$180,000 2001- 

2004 

5/1/99- 

4/30/04 

Simanek $410,000 $136,667 9/1/03- 

8/31/06 

Senseman 2004 


11/30/06 

Porter $61,000 $61,000 11/05- 

10/06 


2006 


2006 

Stallone, Wilson, 

E. 

$3,001,599 $600,320 9/1/01- 

8/31/06 

Stallone $875,000 $175,000 4/1/01- 

6/30/06

$800,000 $200,000 9/1/04- 

11/30/06 

3/15/02- 

1/31/06 

1/1/06- 

12/31/06 

Myocardial Ischemia 

NIH/NEI F32 EY 13920 

(NRSA) 

Ko 

Circadian regulation of 

cGMP-gated ion channels. 

NCI R01 CA61750 Lupton Response to DNA Damage: 

Colon vs Small Intestine 

NCI R01 CA82907 Lupton Diet, Apoptosis and Colon 


USDA 2003-00818 McMurray Nutritional modulation of 

immunity 

NIH/NIEHS U19 ES11387 Mirkes Toxicogenomic Pathway 

Analysis of Sensitive and 

Resistant Mammalian 

Models for 

Neurodevlopmenbtal 


NIH/NIEHS R01 ES08744 Mirkes 70KDHSPs-Modulators of 

Developmental Toxicity 

NIH/NIEHS R21 ES11765 Mirkes A proteomic approach to the 

identification of proteins 

Colgate- 

Mouneimne Early Toxicity Screening for 

Palmolive Grants 


for Alternative 


Research 

NIDA 

R01 DA13188- Nation Heavy metals and polydrug 

03S1 

self-administration 

Exponent - NIDA R01-DA-13188- Nation Heavy Metals and Poly 

NOAA-CIFAR 

01A1 

NSB3612- 

PF900580 

O’Hara and 

Bratton 

Drug Self-Administration 

The Bowhead Whale as a 

Potential Indicator Species 

for Monitoring the Health of 

the Western Arctic/Bering 

Sea Ecosystem Using 

Blubber, Histology, Metal 

and Mineral Indices 

EPA CP-97656501 Olivera Trading Options into 

Watershed Improvement 

Plans for Lake Lewisville: 

Phase II 

9/01-9/04 

Burghardt 8/01/94- 

5/30/05 

Burghardt 5/01/01- 

1/31/05 

Chapkin $290,846 $96,949 9/1/03 - 

8/31/06 

$216,470 $48,229 8/30/01- 

8/31/06 

Tiffany- 

Castiglioni 

$648,000 2001- 

2005 

Bratton $294,392 4/01/00- 

3/30/04 

$176,410 6/01/98- 

5/31/04 


2004 

NIH HL64931 Parker LPS-Induced Endothelial Schroeder $1,125,000 $250,000 2000-

Dysfunction: ecNOS, Ca =2 , 

VEGF 

USDA-CSREES- 

Pietrantonio Functional characterization 

NRI 

and target validation of tick 

(Boophilus microplus) G 

protein-coupled receptors. 

TAMU-Conacyt 

Pillai Quantifying health risks in 

Program 

Mexico associated with 

contaminated fruits and 

vegetables via pathogens in 

irrigation water 

USDA-CSREES Pillai (Co-PI) Microfluidic system for 

capture and concentration 

of microbial contaminants in 

drinking water 

TAMU Dept of 

Veterinary 

Pathobiology 

NIH/NIEHS 

Center for 

Environmental 

Rural Health 

TAMU Office of 

Vice-President of 

Research 

2005 

10/1/03- 

9/30/06 

9/1/05- 

9/1/06 

$126,550 $42,183 8/1/03- 

8/1/06 

135303-1000 Ramaiah Alcoholic Hepatitis $200,000 $50,000 7/1/02- 

6/30/06 

NA Ramaiah Pilot project: Alcoholic 

Hepatitis 

8/1/03- 

7/31/05 

Ramaiah Alcoholic Hepatitis 1/1/03- 

1/1/05 

NIH NA Ramos Osteopontin and Oxidative 

Stress in Atherogenesis 

NIH R01 DK 30343 Raushel Mechanism and Control of 

Urea Biosynthesis 

NIH 

P30 HL66398- Rosenquist Folic Acid and 

01 

Homocysteine: Mechanisms 

DOD-US Army 

MRMC 

DAMD17-02-1- 

0147 

Safe 

of Heart Defects 

Inhibitory Ah Receptor- 

Androgen Receptor 

Crosstalk in Prostate 

Cancer 

NIH/ NIEHS R01-ES04176 Safe 2,3,7,8-TCDD Effects on 


NIGMS F31GM069091 Santillano Neuronal precursor 

regulation during 

Wilson E 04/01/00- 

03/31/04 

9/1/01- 

8/31/06 

Finnell $929,825 $185,965 9/1/01- 

8/31/06 

1/15/02 – 

2/15/05 

1/1/01 - 

12/31/06 


12/31/05

corticogenesis 

NIH/NIDDK 

RO1 

DK41402-18 

Schroeder Fatty-Acid Binding Proteins: 

Ligand Specificity 

NIH DK 41402 Schroeder Fatty Acid Binding 

Protein-Ligand Specificity- 

Administrative Supplement 

for a Drug Screening 

Program for Diabetic 

Complications 

NIH GM31651 Schroeder Asymmetric Distribution of 

Cholesterol in Membranes 

Albaugh 

Senseman Determination of secondary 

Corporation 

drift differences between 

Texas State Soil 

and Water 

Conservation 

Board. 

Senseman 

chemical formulations 

Monitoring surface water for 

selected herbicides. 

Kier $975,420 $254,772 7/1/02- 

6/30/06 

Kier $77,500 $77,500 2005- 

2006 

Kier $973,927 1999 - 

2004 

2005- 

2006 

NIH Simanek Molecular Recognition in 

Dendrimers 

$1,078,500 8/1/02- 

7/3//06 

Welch 

Foundation 

Simanek Molecular Recognition $150,000 6/1/02- 

5/31/05 

NSF-NTE Simanek Engineering on 




Separations 

$410,000 9/1/03- 

8/31/06 

NSF 3134-03 Auburn Simonian Nanoparticle-based 



Organophosphate Chemical 

Warfare Agents and 

Neurotoxic Pesticide 

BARD - 

Binational 

Agricultural 

Research and 

Development 

Fund 

US-3199-OCR Spencer Placental Lactogen 

Enhances Production 

Efficiency in Sheep 

2004 

Wild $650,000 $216,667 10/1/03- 

9/1/06 

$150,000 $50,000 9/1/00- 

5/31/06 

USDA NRI 2001- Spencer Role of Endometrial Glands Burghardt $218,000 $72,667 10/1/03-

02259 in Uterine Function 6/30/06 

NIH 1R01 HD38274 Spencer Mechanisms Regulating 

Uterine Morphogenesis 

Burghardt $536,000 $134,068 10/1/05- 

9/30/06 


Association 

9/01/03-8/31/04 

(no cost ext. - 

Tian 

Regulation of cholesterol 

biosynthesis by hypoxia 

$126,000 7/01/03- 

6/30/05 

DOD 

Neurofibromatosi 

s Research 

Program, 

CDMRP 

8/31/05) 

NF043126 

Tiffany- 

Castiglioni 

inducible factor beta 

The Function of 

Neurofibromin in 

Astrocytyes 

NIH 5R03CA106080 Thompson The Role of Pesticide 

Dispersion Within Texas 

Watersheds in Childhood 

Cancers 

THECB 

Lilly Clinical 

Partners 

Texas Advanced 

Research 

Program 

NIH/NIA 

Welch 

Foundation 

003658-0359c- 

2001 

Turner 

Walker 

Biological Activity of Citrus 

Flavonoids 

Evaluation of Novel 

Downstream Targets of 

PI3K/AKT Signaling as 

Biomarkers of Efficacy for 

PI3K/AKT Inhibitors 

NA Wang Advanced Methodologies 

for Longitudinal/Clustered 

Data with Applications to 

Nutrition and Cancer 

1 R03 AG- 

022614-01 

Weis 

Estrogen, Fatty Acyl CoA, & 

NOS Function in 

Hypertension 

Welch A-915 Wild Chemical Restructuring of 

Allosteric Interactions in 

Regulatory Enzymes 

NIH-NIAID 1 R21 AI55918 Wild (Co-PI) Targets for Drug Design in 

Flaviviral Infection 

NSF 3134-03 Auburn Wild Nanoparticle-based 



Organophosphate Chemical 

01/05- 

12/31/05 

$436,500 $145,500 9/1/03- 

8/31/06 

01/01/02- 

08/31/04 

06/01/04- 

05/31/05 

01/01/02- 

12/31/04 

Stallone $75,000 $25,000 9/1/03- 

8/31/05 

$600,000 $200,000 1/01/03- 

5/31/06 

7/1/03- 

6/1/06 

10/01/03- 

09/30/04

Warfare Agents and 

Neurotoxic Pesticides 

Reactive 

Surfaces Ltd 

Wild 

Industrial Sponsored 

Research Agreement for the 

Optimization and Scale-up 

of CWA Degradative 

Capabilities 

Pacific Northwest PNNL – 8447 Wild Fog-based Enzyme 

National 

Decontamination of 

Laboratory 

Chemical Warfare Agents. 

This study is directed 

toward developing aerosols 

containing enzymes capable 

of detoxifying chemical 

agents. 

Department of TSWG Contract Wilson C Handbook on Best Practices 

Defense 

and Guidelines for Disposal 

of Contaminated Plant and 

Animal Material. 

Muscular 

MDA3681 Wilson, E. Arterial remodeling in 

Dystrophy 

mouse models of muscular 

Association 

dystrophy 

NIH 

1 R21 Wilson, E. Fibrillin-1 and pressureinduced 

EB004106-01 

arterial remodeling 




USDA NRI 2001- 

02166 

Wu 

Progesterone Regulation of 

Placental Nitric Oxide and 

Polyamine Synthesis in Pigs 

NIH/NIEHS U19 ES11387 Zarbl FHCRC/UW 

Toxicogenomics 

Consortium: Project 1, 

Toxicogenomic pathway 

analysis of sensitive and 

resistant mammalian 

models for 

neurodevelopmental 

toxicology 

01/03 – 

03/04 

09/03- 

12/04 

10/1/05 – 

1/31/06 

$253,715 $84,550 1/01/04- 

12/31/06 

$275,000 $125,000 1/01/04- 

12/31/06 

Spencer $230,850 $76,000 9/1/03- 

8/31/06 

Spencer $50,000 $10,000 9/30/01- 

8/31/06 

Mirkes 9/30/01- 

8/31/06

Toxicology - Office of the Provost and Executive Vice President for ...

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