HRV in Autonomic Assessment - PhysioNet

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Autonomic neuropathy and nephropathy „ Steno study prospective assessment – 10.1 years „ 197 type 1 diabetic patients with diabetic nephropathy „ 191 patients with long-standing type 1 diabetes and normoalbuminuria „ Heart rate variability with deep breathing „ Endpoint – fatal and non-fatal cardiovascular disease „ Hazard ratios in a patient with nephropathy and an abnormal HRV „ For reaching the primary end point 6.4 (95% CI 1.5-26.3, P = 0.01) „ For dying 3.3 (95% CI 1.0-10.7; 10.7; P = 0.04) „ HRV is an independent risk factor predicting cardiovascular morbidity and mortality in type 1 diabetic patients with nephropathy Astrup AS et al. Diabetes Care. 2006;29:334-9. 9.
Risk factors for cardiac autonomic neuropathy in type 1 Diabetes „ Age „ HbA1c „ Feeling faint on standing „ Hypertension „ Distal neuropathy „ Other microvascular complications (nephropathy and retinopathy) Witte DR et al Diabetologia 2005
Page 1 and 2: HRV in Diabetes and Other Disorders
Page 3 and 4: Survival % 100 80 60 Gen population
Page 5 and 6: Neuropathy prevalence Rochester Dia
Page 7 and 8: Prevalence of abnormal R-R variatio
Page 9 and 10: Mortality of autonomic neuropathy A
Page 11: Sudden cardiac death „ 21 cases o
Page 15 and 16: CARDIAC PARASYMPATHETIC FUNCTION He
Page 17 and 18: SINUS ARRHYTHMIA „ Respiratory fr
Page 19 and 20: EI_JC.WDQ Respiration Finapres BP P
Page 21 and 22: Time domain statistical measures of
Page 23 and 24: Simulation of the effect of mean he
Page 25: VALSALVA MANOEUVRE „ Stimulus: Ex
Page 29 and 30: 145 139 VAL2_HL.WDQ 78 Valsalva Rat
Page 31 and 32: CARDIAC PARASYMPATHETIC FUNCTION He
Page 33 and 34: 107 61 Measurements • "30:15" rat
Page 35 and 36: Supine Tilt
Page 37 and 38: Power spectral analysis of heart ra
Page 39 and 40: Power spectral analysis of heart ra
Page 41 and 42: Sympathetic neurotransmission • B
Page 43 and 44: Transfer function analysis of respi
Page 45 and 46: Heart rate power spectrum HR PSD [b
Page 48 and 49: Postural tachycardia Terminology
Page 50 and 51: Orthostatic tachycardia 140 BP mmHg
Page 52 and 53: Orthostatic intolerance Features
Page 54 and 55: Baroreflex response - Control 1200
Page 56 and 57: Cardiac Vagal Baroreflex Gain 30 (m

HRV in Autonomic Assessment - PhysioNet

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