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Breakthrough Pain - Dolor Irruptivo.com

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<strong>Breakthrough</strong> <strong>Pain</strong>:<br />

Definitional Problems<br />

• Most studies use a version of:<br />

– A transitory, severe or excruciating pain, which lasts<br />

seconds to hours and is superimposed on a baseline<br />

pain controlled to a moderate or better intensity by an<br />

opioid regimen<br />

• Most studies in the cancer population<br />

– Explains opioid focus<br />

Mercadante et al. Cancer, 2002; 94:832-839.<br />

Svendsen et al. Cancer Surv, 2005; 9:195-206

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