Breakthrough Pain - Dolor Irruptivo.com

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“Rescue Dose” According to Expert Opinion • Expert opinion: – Very little supporting data for re<strong>com</strong>mendations – Advent of rapid onset formulations have questioned some assumptions • Same drug? • Same route? • Proportionate dose? – New question: When should rapid onset opioids be used
“Rescue Dose” • Most <strong>com</strong>mon approach at the present time – Oral or IV/SQ rescue doses • Same drug and route as baseline • “PRN” dose at 5-15% of the total daily dose • Offered every 1-2 hours if oral and every 15-60 minutes if IV/SQ • Dose titration is often necessary
Page 1 and 2: Breakthrough Pain Russell Portenoy,
Page 3 and 4: Breakthrough Pain: Definitional Pro
Page 5 and 6: Breakthrough Pain: Overall Pain Con
Page 7 and 8: Breakthrough Pain: Impact on Mood M
Page 9 and 10: Frequency (%) Breakthrough Pain: Co
Page 11 and 12: Breakthrough Pain: Definitional Pro
Page 13 and 14: Prevalence of Breakthrough Pain •
Page 15 and 16: Cancer-Related Breakthrough Pain: P
Page 17 and 18: Breakthrough Pain: Treatment Issues
Page 25 and 26: Treatment of BTP using Intranasal K
Page 27: “Rescue Dose” According to Expe
Page 31 and 32: “Rescue Dose” • Studies of fi
Page 33 and 34: “Rescue Dose” • New rapid ons
Page 35 and 36: Rapid-Onset “Rescue Dose” • A
Page 37 and 38: Study OTFC in Breakthrough Cancer P
Page 39 and 40: Fentanyl (ng/mL ± SEM) Rapid Onset
Page 41 and 42: Episodes, % RCT of Fentany Pectin N
Page 43 and 44: Rapid Onset Opioids: Concerns • M
Page 45 and 46: Opioid Treatment of Breakthrough Pa

Breakthrough Pain - Dolor Irruptivo.com

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