Two examples of bio-guided isolation, synthesis and ...
Two examples of bio-guided isolation, synthesis and ...
Two examples of bio-guided isolation, synthesis and ...
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Synthesis <strong>of</strong> 2- or 3-substituted quinolines (part 3)<br />
N<br />
Cl<br />
RMgX, Fe(acac) 3<br />
THF, -10 °C-0 °C<br />
N<br />
R<br />
N<br />
76%<br />
N<br />
36%<br />
OH<br />
75% N<br />
N<br />
75%<br />
N<br />
70%<br />
(Seck M. et al Tet. Lett. 2004, 45, 1881-1884)<br />
BioCIS (UMR CNRS 8076)