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KiNET User Guide - Kinexus Bioinformatics Corporation

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Proteins Details<br />

It provides basic information on the proteins measured and has hyperlinks to<br />

Pubmed, Swissprot, Refseq, OMIM and LocusLink. The appropriate<br />

database name will not appear hyperlinked if the Protein does not have the<br />

required information.<br />

Protein Comparison<br />

This page allows the users to perform a pairwise comparison of protein<br />

measured on a same screen. The search brings back details of the samples<br />

where the 2 proteins appear.<br />

On this page the users must first select a screen to compare, then the dropdown<br />

boxes for Protein #1 and Protein #2 are filled with the proteins from<br />

that screen. The users can then pick one protein in each drop-down box and<br />

compare them. They can also narrow down the results using the comboboxes<br />

on the right.<br />

As part of the results, the users see the value of the Pearson correlation<br />

coefficient computed from the values of the %CFC for the 2 proteins on<br />

each sample. As part of the computation of the correlation coefficient a max<br />

value has been set and that value is used in the calculation whenever the<br />

%CFC is greater than that max value. It helps correct the impact of very high<br />

%CFC values on the overall calculation (this is usually the result of a very<br />

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