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EDITORIAL In the news : - Truffle Capital

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<strong>In</strong> <strong>the</strong> <strong>news</strong> :<br />

• Highlight<br />

‐ <strong>Truffle</strong> 100 Europe<br />

• <strong>Truffle</strong> in <strong>the</strong> <strong>news</strong><br />

‐ Sandrine Gasnot joins<br />

<strong>Truffle</strong> capital<br />

• Portfolio News<br />

‐ <strong>In</strong>formation Technology:<br />

PeopleCube, MoMac<br />

Keyyo<br />

‐ Life Sciences :<br />

Néovacs, Carmat, Symetis,<br />

Deinove<br />

‐ Energy :<br />

2‐B Energy, SP3H, Neelogy,<br />

Acerde, Actility, RF‐iT<br />

• Contacts<br />

1 October 20, 2010<br />

2 Dow Jones Venture Source, July 2010<br />

<strong>EDITORIAL</strong><br />

N°17 - October 2010<br />

<strong>Truffle</strong> <strong>Capital</strong> ‐ 5, rue de la Baume 75008 Paris ‐ Tel: +33 1 47 20 22 20 ‐ www.truffle.com<br />

Following <strong>the</strong> success of two recent stock market<br />

listings (€10 million raised on April 15th by <strong>the</strong><br />

<strong>the</strong>rapeutic vaccines company Neovacs and €12<br />

million raised on April 21st by <strong>the</strong> greentech biofuel<br />

start‐up Deinove), <strong>Truffle</strong> <strong>Capital</strong> chalked up its 3rd<br />

successful IPO in 2010 after Carmat (a French<br />

company developing a total artificial implantable<br />

heart) listed on <strong>the</strong> NYSE Euronext Paris Alternext market.<br />

Despite tough market conditions, Carmat raised €16.5 million (€18.75 per share),<br />

which corresponds to <strong>the</strong> typical amount for this type of transaction. <strong>Truffle</strong> <strong>Capital</strong><br />

is Carmat’s co‐founder (along with EADS and <strong>the</strong> Fondation Carpentier), <strong>the</strong><br />

company’s main shareholder (with 31.8% of <strong>the</strong> post‐money stock) and <strong>the</strong> sole<br />

venture capital investor (€5 million invested in 2008, €1 million in 2009 and €2<br />

million this year).<br />

Since <strong>the</strong> IPO, market interest in <strong>the</strong> company has grown and Carmat has already<br />

achieved a market cap of €94 million 1 . This is one of <strong>the</strong> most striking performances<br />

ever on Alternext and benefits both <strong>the</strong> direct shareholders and <strong>the</strong> investors who<br />

entrusted <strong>the</strong>ir capital to <strong>Truffle</strong>'s funds.<br />

Carmat seems to have all <strong>the</strong> key factors for stock market success: cutting edge<br />

technology, a highly innovative product, a quality management team led by<br />

Marcello Conviti and Patrick Coulombier, strong medical demand and a high‐<br />

potential market with clear short‐term deadlines. The key milestone will be <strong>the</strong> first<br />

implantations in patients, scheduled for late 2011.<br />

According to Dow Jones Venture Source, 2010 has already witnessed 8 IPOs by<br />

companies backed by VC investors, raising a total of €93 million 2 . With €38 million<br />

raised so far, <strong>Truffle</strong> <strong>Capital</strong> accounts for 40% of <strong>the</strong> total and has thus confirming its<br />

solid position among Europe's leading venture capital firms.<br />

Henri Moulard, Jean-François Fourt, Dr Philippe Pouletty, Bernard-Louis Roques<br />

<strong>Truffle</strong> <strong>Capital</strong> is an independent European venture capital firm established in 2002, with a<br />

share capital of €1.7 million. We manage funds over €430 million, of which €210 million<br />

came from FCPIs.


HIGHLIGHT<br />

N°17 October 2010<br />

TRUFFLE CAPITAL UNVEILS THE FIFTH EDITION OF THE TRUFFLE 100 EUROPE<br />

<strong>Truffle</strong> <strong>Capital</strong> publishes its 5th annual ranking of <strong>the</strong><br />

top 100 European software companies at ICT 2010 in<br />

Brussels, <strong>the</strong> biggest European forum dedicated to<br />

digital research and innovation.<br />

The <strong>Truffle</strong> 100 Europe has been drawn up with <strong>the</strong><br />

support of Neelie Kroes (European Commissioner for<br />

<strong>the</strong> Digital Agenda) and Syntec <strong>In</strong>formatique and in<br />

collaboration with analysts IDC (www.idc.com) and<br />

CXP (www.cxp.fr), who performed <strong>the</strong> survey on<br />

which <strong>the</strong> ranking is based.<br />

"The latest edition of <strong>the</strong> <strong>Truffle</strong> 100 Europe<br />

emphasizes <strong>the</strong> dynamism of <strong>the</strong> European software<br />

industry in what is never<strong>the</strong>less a difficult economic<br />

climate.<br />

Key figures from <strong>the</strong> <strong>Truffle</strong> 100 Europe:<br />

• Total turnover for 2009 was €27.1 billion, compared<br />

with €25 billion in 2008. 79% of this figure was<br />

generated by <strong>the</strong> ranking's top 25 companies (down<br />

from 70% in 2008).<br />

• The mean growth in turnover was 8.4% in 2009<br />

• 47 vendors posted revenues of over €100 million and<br />

72 vendors earned over €50 million. All <strong>Truffle</strong> 100<br />

Europe companies had revenues of over €25 million.<br />

• Profits rose from €3.6 billion in 2008 to €3.7 billion in<br />

2009 (i.e. a slight increase).<br />

2<br />

Despite <strong>the</strong> economic crisis, software vendors have<br />

demonstrated that <strong>the</strong>y constitute a strategic and<br />

astonishingly resilient industry. The software industry<br />

is growing and has bounced back quickly (with a 8.4%<br />

increase in total turnover in 2009). With 3.8bn€<br />

invested in R&D and 54 000 highly qualified R&D jobs<br />

<strong>the</strong>y constitute a strategic industry that is critical for<br />

job creation & GDP growth in Europe. European<br />

governments must accentuate supporting measures<br />

so that this industry can create more jobs. Europe's<br />

industrial future, economic growth and technological<br />

independence rely on its ability to develop a<br />

sustainable software industry" stated Bernard‐Louis<br />

Roques, General Partner and co‐Founder of <strong>Truffle</strong><br />

<strong>Capital</strong>.<br />

• The number of R&D jobs rose slightly, from 52,020 in<br />

2008 to 54,180 in 2009.<br />

• <strong>In</strong> 2009, 74% of <strong>the</strong> <strong>Truffle</strong> 100 Europe firms were<br />

listed on one or more stock markets and accounted<br />

for 88.9% of sales, 88.7% of <strong>the</strong> R&D and 95.6% of<br />

profits.<br />

• R&D investment increased from €3.64 billion in 2008<br />

to €3.82 billion in 2009 (a 4.8% increase after a 3%<br />

drop between 2007 and 2008).<br />

The measures most requested by surveyed software firms throughout Europe were fiscal incentives (such as research<br />

tax credits), followed by public R&D funding, Small Business Acts and increased venture capital investment.<br />

TRUFFLE IN THE NEWS<br />

Sandrine Gasnot joins <strong>Truffle</strong> <strong>Capital</strong>’s team as Fund Controller<br />

Sandrine joined <strong>Truffle</strong> <strong>Capital</strong> in May 2010 as Fund Controller, bringing 20 years of<br />

experience in finance to <strong>the</strong> team. <strong>In</strong> 1987, Sandrine Gasnot worked in financial<br />

markets at ABN Amro Bank. Then she joined HSBC, one of <strong>the</strong> top global groups<br />

specialized in banking and financial services. <strong>In</strong> 2008, she expanded her experience in<br />

<strong>the</strong> banking field by joining CACEIS Bank, one of France’s biggest depositary and fund<br />

administrator.<br />

Having worked in back‐office teams in international and French financial markets, she<br />

has knowledge of not only <strong>the</strong> domestic but also <strong>the</strong> global financial sector.


PORTFOLIO NEWS<br />

N°17 October 2010<br />

• <strong>In</strong>formation Technology<br />

<strong>In</strong> brief<br />

PeopleCube is a leading provider of on‐demand calendaring, resource and facilities management software<br />

solutions for medium and large enterprises worldwide. They signed over a dozen Fortune 1000 companies as<br />

clients since January 2010, including Deutsche Bank, Thomson Reuters, Blackrock Financial, Morgan Stanley,<br />

Southwestern Energy, Spawar, Merck...) and continue innovating with <strong>the</strong>ir new business intelligence and<br />

subscription packages.<br />

MoMac delivers iPad and iPhone Apps for <strong>the</strong> leading French magazine l'Express and launches a new mobile<br />

internet portal for MSN<br />

L'Express, founded in 1953, is one of <strong>the</strong> leading<br />

French weekly <strong>news</strong> magazines, published in Paris.<br />

Its website http://www.lexpress.fr is also one of <strong>the</strong><br />

largest media websites, ga<strong>the</strong>ring 8.6 million visits<br />

per month.<br />

MoMac, via its Paris‐based subsidiary, was selected<br />

to design and build <strong>the</strong> iPhone and iPad applications<br />

for l'Express. The company responded to L’Express’<br />

quest for a slick and clear design that could embed<br />

various types of content: articles, graphics,<br />

slideshows and videos.<br />

3<br />

The result: a set of applications that have become<br />

one of <strong>the</strong> best cases in <strong>news</strong> applications on <strong>the</strong><br />

AppStore and are now used daily by thousands of<br />

iPhone and iPad owners.<br />

Produced entirely at MoMac, <strong>the</strong>se applications<br />

cover <strong>the</strong> following features:<br />

� News articles in several categories: world and<br />

domestic <strong>news</strong>, politics, business, lifestyle...<br />

� Easy browsing though articles, just like turning<br />

pages<br />

� Exclusive photos slideshows<br />

� Daily video feeds by Chief Editor Christophe<br />

Barbier<br />

� Offline content synchronisation<br />

� Sharing articles on Facebook, twitter, or via email<br />

MoMac was also selected to work with MSN to<br />

launch of <strong>the</strong>ir new mobile internet portal. MSN.nl is<br />

<strong>the</strong> Dutch destination for global digital giant MSN,<br />

and one of <strong>the</strong> leading internet destinations in <strong>the</strong><br />

Ne<strong>the</strong>rlands.<br />

<strong>In</strong> response to rapidly increasing visits from mobile<br />

users across Holland, MSN decided to upgrade <strong>the</strong>ir<br />

mobile experience, with a state‐of‐<strong>the</strong>‐art mobile<br />

website, that had to meet <strong>the</strong> following objectives:


N°17 October 2010<br />

� Offer users a comprehensive range of content and<br />

functionality, including all of <strong>the</strong> existing MSN<br />

services, in addition to <strong>the</strong> most compelling <strong>news</strong><br />

and entertainment<br />

� Present a rich intuitive user experience that struck<br />

a balance between simplicity, design and fast<br />

page display<br />

Keyyo: acquisition of Mobeel Group, a Mobile Virtual Network Operator (MVNO)<br />

Keyyo, a VoIP operator, recently acquired 100% of<br />

Mobeel Group’s capital. Mobeel, a new arrival on <strong>the</strong><br />

French market, is a mobile virtual network operator<br />

offering competively‐priced mobile calling plans via a<br />

purely‐online distribution model.<br />

• Life Sciences<br />

Neovacs, a biotech company focused on an active<br />

immuno<strong>the</strong>rapy technology with applications in <strong>the</strong><br />

treatment of autoimmune diseases, inflammatory<br />

diseases and cancer, announced that its TNF‐Kinoid<br />

product candidate has been selected by Windhover,<br />

an international pharmaceutical and healthcare<br />

information company, as one of <strong>the</strong> top ten projects<br />

to watch in <strong>the</strong> inflammatory/autoimmune area.<br />

<strong>In</strong> addition, Neovacs will present its TNF‐Kinoid<br />

programs and notably <strong>the</strong> results of a Phase 1/2<br />

4<br />

� Provide flexibility for MSN to rapidly change and<br />

update <strong>the</strong> portal ensuring <strong>the</strong> offering was<br />

always fresh and appealing<br />

� Finally, as a leading B2C services supplier, ensure<br />

optimized mobile rendering for 100% of <strong>the</strong>ir<br />

users handsets<br />

The acquisition enables Keyyo to enlarge its VOIP<br />

offer to business customers with a mobile plan, while<br />

also benefitting from Mobeel’s e‐commerce<br />

expertise to cross‐sell to <strong>the</strong> company’s existing<br />

client base.<br />

study in 21 patients with Crohn’s Disease, at <strong>the</strong><br />

Therapeutic Area Partnerships meeting, which will<br />

take place at <strong>the</strong> Westin Copley Place in Boston, MA.<br />

from 2 to 4 November 2010.<br />

The TNF‐Kinoid is in phase 2 testing in rheumatoid<br />

arthritis.<br />

The company is also advancing in <strong>the</strong> Phase I/II<br />

international trial of a second product candidate, IFN<br />

‐Kinoid, dedicated to <strong>the</strong> treatment of lupus.


N°17 October 2010<br />

Carmat, <strong>the</strong> designer and developer of <strong>the</strong> world’s<br />

most advanced total artificial heart, had its Scientific<br />

Advisory Board meet on September 12 at <strong>the</strong> venue<br />

of <strong>the</strong> 24 th Annual Meeting of <strong>the</strong> European<br />

Association for Cardiothoracic Surgery (EACTS) in<br />

Geneva (Switzerland). The Scientific Advisory Board<br />

(chaired by Professor Alain Carpentier) discussed <strong>the</strong><br />

Symetis, a company developing new transca<strong>the</strong>ter<br />

aortic valve implantation (TAVI) systems, recently<br />

completed patient enrolment in its ACURATE TA<br />

first‐in‐man (FIM) clinical study and positive<br />

preliminary results. ACURATE TA is a self‐aligning<br />

nitinol stent valve designed for optimal trans‐apical<br />

delivery, providing <strong>the</strong> physician with unmatched<br />

positioning tolerance and ease of use. The study was<br />

5<br />

preparation of Carmat's clinical trials through to <strong>the</strong><br />

end of 2011. <strong>In</strong> July, Carmat successfully listed on <strong>the</strong><br />

Alternext market of NYSE Euronext, with a view to<br />

performing <strong>the</strong> first implantation of its total artificial<br />

heart in a patient in 2011 and commercializing <strong>the</strong><br />

device by 2013.<br />

conducted on 40 patients and is <strong>the</strong> largest 2nd<br />

generation First <strong>In</strong> Man (FIM) study ever conducted.<br />

Successful valve implantation with <strong>the</strong> ACURATE TA<br />

was done in 38 patients (95.0%). Symetis will soon<br />

begin a pilot clinical study, a major step toward<br />

achieving European compliance and <strong>the</strong> CE mark. The<br />

company has just received 25 million Swiss Francs in<br />

a new round of financing, mainly from <strong>Truffle</strong> <strong>Capital</strong>.<br />

Deinove, <strong>the</strong> biofuels and green chemistry specialist, partners with VTT Technical Research Centre of<br />

Finland having a Centre of Excellence in White Biotechnology ‐ Green Chemistry<br />

Deinove, <strong>the</strong> world's leading specialist in <strong>the</strong><br />

application of deinococci bacteria to biofuels and<br />

green chemistry, partnered in July with <strong>the</strong> top<br />

European research centre on industrial enzymes and<br />

bioprocesses, VTT Technical Research Centre of<br />

Finland.<br />

Ten senior VTT researchers will team up with Deinove<br />

and its French academic partners from CNRS and<br />

INSA to leverage <strong>the</strong> exceptional properties of<br />

Deinococcus bacteria in <strong>the</strong> digestion of biomass and<br />

<strong>the</strong> development of an integrated process for <strong>the</strong><br />

bioproduction of ethanol and chemicals from<br />

renewable feedstocks.<br />

The general objective of <strong>the</strong> work plan established by<br />

Deinove and VTT is to evaluate <strong>the</strong> different<br />

Deinococcus candidate strains screened by Deinove<br />

for its cellulosic ethanol production process. The<br />

Deinol process will <strong>the</strong>n be scaled‐up and tested in an<br />

industrial pilot by <strong>the</strong> sugar‐company TEREOS.<br />

Deinove also received in September <strong>the</strong> first<br />

installment granted by <strong>the</strong> French <strong>In</strong>novation Agency<br />

Oseo (Strategic <strong>In</strong>dustrial <strong>In</strong>novation programme) to<br />

<strong>the</strong> Deinol project for <strong>the</strong> production of cellulosic<br />

ethanol using <strong>the</strong> Deinococcus. The payment by Oseo<br />

of <strong>the</strong> first installment, of € 1,4 million out of a total<br />

of €6 million funding granted to <strong>the</strong> DEINOL<br />

project,aims at opening up (by 2014) new pathways<br />

for lignocellulosic ("second‐generation") ethanol<br />

production in existing industrial installations.<br />

Deinove also appointed Philippe Duval (Chairman of<br />

<strong>the</strong> Executive Board at Tereos, Deinove’s partner and<br />

investor in Deinove’s IPO) to its Board of Directors.


• Energy<br />

<strong>In</strong> brief<br />

N°17 October 2010<br />

The Crown Estate, a British organization with a property portfolio encompassing many of <strong>the</strong> UK’s cityscapes,<br />

ancient forests, farms, parkland, coastline and communities, has awarded 2‐B Energy <strong>the</strong> right to demonstrate<br />

2B‐Energy’s two offshore wind turbines in Scotland. 2B‐Energy’ will launch offshore wind demonstration sites<br />

to begin initial survey and consultation processes for <strong>the</strong>ir sites while <strong>the</strong> Scottish Government conducts a<br />

Strategic Environmental Assessment (SEA) for offshore wind within Scottish territorial waters.<br />

SP3H, a leader in <strong>the</strong> field of fuel profiling, which recently raised €2,3 million in January from <strong>Truffle</strong> <strong>Capital</strong>,<br />

launched a fuel sensor called Niris, based on SP3H’s technology, HCP (HydroCarbon Profiler technology). SP3H<br />

launched Niris in partnership with CMR for marine and heavy duty. SP3H also received <strong>the</strong> 2010 GEP<br />

<strong>In</strong>novation Award for SMEs, which acknowledges SP3H’s technology and <strong>the</strong>ir open innovation strategy.<br />

<strong>Truffle</strong> <strong>Capital</strong> makes three new investments in <strong>the</strong> energy sector<br />

<strong>In</strong> September, <strong>Truffle</strong> <strong>Capital</strong> concluded three new investments in <strong>the</strong>se particularly promising energy<br />

companies:<br />

• Neelogy develops and commercialises innovative magnetic sensors. The company's technology enables<br />

<strong>the</strong> high‐precision measurement of DC and AC currents in complex environments. The lightweight,<br />

flexible sensors are very well suited to emerging needs for improved energy efficiency: energy<br />

measurement, battery management, <strong>the</strong> mass reduction of static converters and electric motor<br />

control and diagnostics.<br />

<strong>Truffle</strong> <strong>Capital</strong> has invested €3 million in a second round of financing which will enable Neelogy to fund<br />

its investments and collaborative R&D programmes with specialists in <strong>the</strong> fields of energy conversion,<br />

<strong>the</strong> protection of DC installations and <strong>the</strong> measurement of AC energy.<br />

• The start‐up Acerde was founded in 2006 by Didier Pique. It is developing and leveraging its expertise<br />

in <strong>the</strong> design and formulation of materials with high‐performance qualities, based on high‐<br />

temperature chemical vapour deposition. The first application of Acerde's technology concerns X‐ray<br />

tube anodes and could turn <strong>the</strong> company into a key partner for computed tomography scanner<br />

manufacturers.<br />

<strong>Truffle</strong> <strong>Capital</strong> has invested €1.5 million in <strong>the</strong> company's first round of financing, so that Acerde can<br />

develop its technology for X‐ray tube anodes and thus generate short‐term revenue.<br />

6


N°17 October 2010<br />

• Actility was founded in 2010 by IT industry veteran Olivier Hersent. It is developing a machine‐to‐<br />

machine communication platform for new‐generation telecom networks. The goal is to develop client<br />

solutions through <strong>the</strong> use of communication platforms which will generate revenues for <strong>the</strong> company<br />

via software, accessories and licensing.<br />

<strong>Truffle</strong> <strong>Capital</strong> has invested €3 million in <strong>the</strong> company's first round of financing, in order to fund <strong>the</strong><br />

company's first communication platform (due to be operational in 2011).<br />

RF‐iT Solutions optimizes retail processes of Gerry Weber brand, thanks to new detego® RFID Starter Kit, a<br />

package for directly managing stocks.<br />

RF‐iT Solutions, a leading European provider of integrated RFID solutions offering standard modules for <strong>the</strong><br />

optimization of business processes in fashion industry, in partnership with Pranke GmbH, have created a<br />

package for directly managing stocks using <strong>the</strong> innovative RFID technology in <strong>the</strong> retail industry.<br />

Since this summer on, all items from <strong>the</strong> lifestyle company Gerry Weber will be equipped with RFID tags. As a<br />

result, each retailer who sells Gerry Weber products can now also benefit from this technology.<br />

Benefits of this product are multiple: improvement in inventory management, <strong>the</strong> supplier can quickly detect<br />

an out of stock situation and close it immediately. Retailers can register all deliveries and <strong>the</strong> current<br />

inventory with a hand‐held device and automatically check for completeness. Customers who can find <strong>the</strong>ir<br />

preferred products at <strong>the</strong> shop are satisfied customers who come back and display tremendous brand loyalty.<br />

Starter kits were presented in June at Gerry Weber’s franchisers and found a very positive response: "The<br />

RFID Starter kit provides a quick and efficient entry into an RFID‐based inventory management for our<br />

retailers and that in all major European languages", ensures Dr. David Frink, managing director of IT, logistics<br />

and production at Gerry Weber.<br />

More than 340 Houses of Gerry Weber, over 1,860 shop‐in‐shops as well as several mono‐brand online shops<br />

successfully showcase <strong>the</strong> brands of Gerry Weber <strong>In</strong>ternational AG to consumers worldwide. Today, <strong>the</strong> five<br />

brands are managed and designed under <strong>the</strong> umbrella of <strong>the</strong> holding company in Halle. Licensed products<br />

such as shoes and bags complement <strong>the</strong> range and <strong>the</strong> versatile fashion strikes <strong>the</strong> same chord with<br />

customers, whe<strong>the</strong>r in Berlin, Dubai or Ottawa. That is how Gerry Weber became listed on <strong>the</strong> stock exchange<br />

and a worldwide known fashion and lifestyle company.<br />

7


CONTACTS<br />

<strong>In</strong>vestor Relations<br />

Sneha HIREMATH<br />

<strong>Truffle</strong> <strong>Capital</strong><br />

5 rue de la Baume<br />

75008 Paris<br />

Email:<br />

sneha@truffle.com<br />

Web : www.truffle.com<br />

N°17 October 2010<br />

8<br />

Press Relations<br />

Caroline CARMAGNOL<br />

Alize RP<br />

33, rue de Surène<br />

75008 Paris<br />

Tel: +33 42 68 86 43<br />

Mob: + 33 6 64 18 99 59<br />

Fax. : +33 1 42 68 06 51<br />

Email: caroline@alizerp.com

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