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Oral Contraceptive Use and Ovarian Cancer - Library

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CDC-EIS: OCs <strong>and</strong> <strong>Ovarian</strong> <strong>Cancer</strong> (811-X11) - Participant’s Guide page 10<br />

Table 2. Ever-use of oral contraceptives <strong>and</strong> risk of ovarian cancer, stratified by age, <strong>Cancer</strong> <strong>and</strong> Steroid<br />

Hormone Study, 1980-1981<br />

Ages 20-39 years<br />

Ever user<br />

Case<br />

46<br />

Control<br />

285<br />

Total<br />

H 1 = 331<br />

OR = 0.69<br />

Expected(a) = 48.73<br />

MH variance = 6.66<br />

Never user 12 51 H 0 = 63<br />

MH Chi = -1.06<br />

95% CLs = 0.34, 1.38<br />

Total V 1 = 58 V 0 = 336 T = 394<br />

Ages 40-49 years<br />

Case Control Total OR = _____<br />

Ever user 30 463 H 1 = 493<br />

Expected(a) = _____<br />

MH variance = 13.39<br />

Never user 30 301 H 0 = 331 MH Chi = _____<br />

Total V 1 = 60 V 0 = 764 T = 824<br />

95% CLs = 0.38, 1.10<br />

Ages 50-54 years<br />

Ever user<br />

Case<br />

17<br />

Control<br />

211<br />

Total<br />

H 1 = 228<br />

OR = 0.61<br />

Expected(a) = 23.06<br />

MH variance = 12.91<br />

Never user 44 331 H 0 = 375<br />

MH Chi = -1.69<br />

95% CLs = 0.34, 1.08<br />

Total V 1 = 61 V 0 = 542 T = 603<br />

Question 11a:<br />

Using the data in Table 2, calculate the odds ratio for the 40- to 49-year age stratum.<br />

Question 11b:<br />

Using the data in Table 2, calculate the expected value of cell A for the 40- to 49-year<br />

age stratum.<br />

Question 11c:<br />

Using the data in Table 2, calculate the Mantel-Haenszel chi for the 40- to 49-year age<br />

stratum.

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