guidelines for the management of urological cancer - Merseyside ...
guidelines for the management of urological cancer - Merseyside ...
guidelines for the management of urological cancer - Merseyside ...
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Appendix 5 - TCC Algorithm: New Non-muscle Invasive Tumour<br />
First TURBT<br />
Non Muscle invasive<br />
Muscle Invasive<br />
See Muscle invasive<br />
algorithm<br />
G1pTa / G2pTa<br />
G2pT1<br />
G3pTa, G3pT1 or CIS<br />
Local MDT<br />
Single dose <strong>of</strong> intravesical<br />
chemo at resection<br />
Flexi cysto at 3/12 (GA or<br />
Flexi)<br />
Assign risk group at first<br />
cystectomy<br />
Solitary tumour initially<br />
Local MDT<br />
6x weekly intravesical chemo<strong>the</strong>rapy<br />
1 st check cysto under GA at 4/12 <strong>the</strong>n<br />
3/12 flexis <strong>for</strong> 2 years, <strong>the</strong>n 6/12 <strong>for</strong> 2<br />
years, <strong>the</strong>n annual <strong>for</strong> life<br />
Multifocal tumour initially<br />
SMDT<br />
Pathology review by experienced uropathologist<br />
Consider 2 nd look TURBT<br />
BCG<br />
Consider cystectomy<br />
Clear Recurrence Clear Recurrence<br />
Low Risk<br />
Flexi at 1 year <strong>the</strong>n<br />
annually <strong>for</strong> 5 years as<br />
per EAU Guidance.<br />
Then annual urine<br />
cytology analysis by GP<br />
Medium Risk<br />
3/12 flexis <strong>for</strong> 1 year <strong>the</strong>n<br />
6/12 flexis <strong>for</strong> 3 years <strong>the</strong>n<br />
annual flexis <strong>for</strong> life<br />
High Risk<br />
6 doses <strong>of</strong> intravesical<br />
chemo <strong>the</strong>n 3/13 flexi <strong>for</strong> 1<br />
year <strong>the</strong>n 6/12 flexi <strong>for</strong> 2<br />
years <strong>the</strong>n annual flexi <strong>for</strong><br />
life<br />
BCG protocol<br />
Induction course<br />
6 weeks with GA cysto and biopsy 8/52<br />
after maintenance schedule as agreed local<br />
protocol.<br />
Monitoring<br />
3/12 flexi <strong>for</strong> 2 years <strong>the</strong>n 6/12 <strong>for</strong> 3 years<br />
<strong>the</strong>n annually <strong>for</strong> life<br />
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