Surgical Management of Ulcerative Colitis - Department of Surgery ...

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www.downstatesurgery.org Medical Management • Steroids • Moderate to severe • HTN, hyperglycemia, cataracts, osteoporosis, osteomalacia • Budesonide, beclomethasone undergo rapid hepatic degradation to limit systemic toxicity
www.downstatesurgery.org Medical Management Immunosuppressive Agents • Azathioprine, 6-MCP • Interfere w/ nucleic acid synthesis • Good for those who failed salicylate Tx or are dependent on steroids (6-12 wk onset of axn) • Cyclosporine • Interferes w/ T cell funxn • Helps acute flares 80% • Methotrexate • Folate antagonist • Infliximab (Remicade) • Monoclonal Ab against TNF alpha • >50% w/ moderate to severe Dz respond
Page 1 and 2: www.downstatesurgery.org Surgical M
Page 3 and 4: www.downstatesurgery.org Patient Pr
Page 5 and 6: www.downstatesurgery.org Surgical M
Page 7 and 8: www.downstatesurgery.org Etiology
Page 9 and 10: www.downstatesurgery.org Liu et al,
Page 11 and 12: www.downstatesurgery.org Gross Path
Page 13 and 14: www.downstatesurgery.org Lead Pipe
Page 15 and 16: www.downstatesurgery.org Diagnosis
Page 17 and 18: Indications for Emergent Surgery
Page 19 and 20: www.downstatesurgery.org Risk for C
Page 21 and 22: www.downstatesurgery.org Proctocole
Page 23 and 24: www.downstatesurgery.org Continent
Page 25 and 26: • Offered a curative resection an
Page 27 and 28: www.downstatesurgery.org Total Proc
Page 29 and 30: A. J-pouch, B. S-pouch, C. Side-to-
Page 31 and 32: www.downstatesurgery.org Ileal J-Po
Page 33 and 34: www.downstatesurgery.org Double- St
Page 35 and 36: Salient Points Pathophysiology sti
Page 37: www.downstatesurgery.org Medical Ma
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Surgical Management of Ulcerative Colitis - Department of Surgery ...

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