Chapter 9 - Lipids and Biological Membranes
Chapter 9 - Lipids and Biological Membranes
Chapter 9 - Lipids and Biological Membranes
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Membrane StructureThe technique of freeze-fracture electron microscopy (EM), in which a membrane isfrozen in liquid nitrogen <strong>and</strong> shattered with a sharp blade, illustrated the bilayer nature ofmembranes.EM studies also revealed that the interior face of each monolayer (leaflet) is studded withglobular particles that are integral membrane proteins.The fluid mosaic model of a plasma membrane was proposed by Singer <strong>and</strong> Nicholson in1972, <strong>and</strong> is illustrated in Figure 9-26.
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