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Acanthaceae - International Journal of Pharmaceutical and ...

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P.Praveen SriKumar <strong>and</strong> P.Pardhasaradhi, Int J Pharm Biomed Res 2013, 4(3), 145-148 147Table1Effect <strong>of</strong> aerial part <strong>of</strong> Ruellia tuberose on pH, total acidity, free acidity, ulcer index <strong>and</strong> % inhibition <strong>of</strong> ulcer index in pylorus ligation induced ulceration inratsSl.No. Compound Dose pH Total acidiy(mEq/L)Free acidity(mEq/L)Ulcer index% inhibition <strong>of</strong>ulcer indexMean±SEM1 Control Water 2.81±0.03 102.2 ± 0.06 86.4 ± 0.96 3.70 -- 8.6 ± 0.202 Ethyl acetate extract 250mg/kg 3.85 ± 0.03 60 ± 0.24 56 ± 0.15 1.64 55.6 3.8 ± 0.973 Ethyl acetate extract 500mg/kg 4.50 ± 0.22* 56 ± 0.15* 46.96 ± 0.24* 0.46 87.56 2.2 ± 0.20*4 Rantidine 20mg/kg 5.35 ± 0.22* 30.4 ± 0.48* 12.50 ± 0.26* --- 100 --Values were expressed as (Mean ± SEM), n=6,*p

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