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RT 02-03 JJ07 main web - Respiratory Therapy Website

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PRODUCT REVIEW<br />

Firefighters' Lungs: Managing Health<br />

Risks with High-Frequency Chest<br />

Compression<br />

Jane M. Braverman, PhD; Mario J. Nozzarella<br />

Firefighters exposed to inhalation of ultra-fine particles (UFP)<br />

may face long-term pulmonary health risks. 1,2 Inhaled fine<br />

particles transport bacteria, viruses, funguses, allergens, and<br />

toxic substances to normally sterile lower airways. 3 Injury and<br />

illness caused by inhalation of smoke and dust-borne UFP are<br />

common following major fire, explosive, or industrial disasters. 4-<br />

6 Robust studies document the prevalence and persistence of a<br />

distinct pattern of respiratory pathology suffered by emergency<br />

responders and clean-up workers and by residents living near<br />

the site of the World Trade Center (WTC) disaster. 7-15 Although<br />

the precise mechanisms of what is now called WTC disease are<br />

incompletely understood, it is clear that excess exposure to<br />

smoke, byproducts of combustion and the fine dust generated<br />

by structural collapse triggered an intense inflammatory<br />

response and a constellation of other symptoms in thousands of<br />

individuals. 16-18 UFP accumulated in the smaller airways is an<br />

established etiological factor in the development of many<br />

secondary lung diseases including chronic bronchitis,<br />

emphysema, bronchiectaisis and progressive massive fibrosis<br />

(PMF). 19-23 Cardiovascular effects are well known. 24 Cancer risks<br />

are suspected but unconfirmed. 25,26<br />

Reflections on the aftermath of the WTC tragedy underscore the<br />

urgency of identifying strategies to protect firefighters from<br />

harmful UFP exposures. 27 Theoretically, at least some health<br />

consequences could have been prevented with timely use of<br />

protective respiratory gear. However, in “real-world” emergency<br />

and disaster situations, an expectation of proper and consistent<br />

use of such equipment is simply not realistic. 28-29,42 For exposed<br />

firefighters, prompt removal of inhaled UFP may be a more<br />

practical intervention. A therapy called high-frequency chest<br />

compression (HFCC) is ideally suited to perform this function.<br />

HFCC is shown to enhance mobilization and expectoration of<br />

particulate-laden mucus from the lower airways. 29,30 A new<br />

HCCF device, the inCourage PAC (Portable Airway Clearance),<br />

has been designed specifically to meet the needs of firefighters<br />

both on-site and in the firehouse.<br />

This article was provided by RespirTech.<br />

Introduction<br />

Firefighters are a vital group of public servants whose work<br />

often exposes them to hazardous conditions. Immediate risks to<br />

life and limb associated with collapsing structures, intense heat,<br />

smoke inhalation and burn injury are part of the job. Inhaled<br />

larger particles, an obvious and annoying problem, are caught in<br />

the nose and rapidly eliminated by coughing or sneezing. Less<br />

appreciated is the deposition and accumulation of ultrafine<br />

particles (UFP) that may enter the lower regions of the lung and<br />

have long-term health effects.<br />

UFP are defined as particles of any composition less than 5<br />

microns in diameter. Several epidemiological studies<br />

demonstrate the adverse effects of occupational inhalation of<br />

UFP among workers exposed to coal dust, 32 silica, 33 asbestos<br />

<strong>Respiratory</strong> <strong>Therapy</strong> Vol. 2 No. 3 � June-July 2007 29<br />

33, 35<br />

silage36 and other substances. 37 Until recently, however, there<br />

have been few inquiries into the health risks of inhaled UFP<br />

among firefighters. 38-45 That neglect was corrected following the<br />

disaster that struck the WTC towers in lower Manhattan on<br />

September 11, 2001. Since that event, the focus on occupational<br />

lung disease has shifted sharply to studies involving firefighters<br />

and emergency rescue/cleanup workers. Well before the dust<br />

settled, it became apparent that health consequences were<br />

likely to be significant. Early reactions have proven prescient<br />

but vastly understated. According to one observer, WTC dust —<br />

containing everything from melted plastics, pulverized concrete,<br />

burnt jet fuel and asbestos —“may have health effects that<br />

could linger for days or weeks.” 46 Clinical evidence of serious<br />

health problems surfaced shortly after the attack. Initial studies<br />

found that many firefighters had developed “trade center<br />

cough,” a stubborn hacking that caused them to cough up soot<br />

12,13, 17<br />

and dust particles.<br />

By January 20<strong>02</strong>, at least 300 firefighters were on leave for<br />

respiratory problems; that number has since grown<br />

dramatically. Approximately 40,000 rescue and recovery<br />

workers were exposed to caustic dust and toxic pollutants<br />

following the collapse of the WTC twin towers. 47 All 11,000<br />

participating members of the Fire Department of New York<br />

(FDNY) had significant exposure because they were caught in

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