Hot Topics in Pediatric Infectious Diseases - Duke Pediatrics Intranet

If you follow my math…• Let’s say the current rate of OB is 0.5%• That means that to prevent one case of possiblemeningitis– You would see 20,000 children, of which 100 would havebacteremia, of which one has meningitis– You would have given up to 10,000 of those kids empiricantibiotics– 1,000 of those kids would have had a false positive bloodculture– AND, there is no reliable data that the one case ofmeningitis would have done better than if you had justwaited until he had the first signs of meningitis