PATHways - American College of Veterinary Pathologists
PATHways - American College of Veterinary Pathologists
PATHways - American College of Veterinary Pathologists
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Volume 3, Issue 1 Page 9<br />
Case Report<br />
The case <strong>of</strong> the mass-Laden Macaque<br />
Microscopic Appearance…………….<br />
200µm<br />
At higher magnification, the wall <strong>of</strong> the cysts was composed <strong>of</strong> ectopic endometrial tissue with epithelium,<br />
glands, and stroma.<br />
Histopathology: The outer surface <strong>of</strong> the uterus, ovary, broad ligament and colon<br />
were distorted and covered by many small coalescing cystic masses. The cysts were<br />
variably filled with erythrocytes, few neutrophils, macrophages and cellular debris and<br />
were lined by a single layer <strong>of</strong> well-differentiated glandular epithelium, morphologically<br />
consistent with endometrium. This epithelial layer was supported by spindleshaped<br />
endometrial stromal cells which merged into the adjoining smooth muscle or<br />
connective tissue. There were multiple interspersed areas <strong>of</strong> fibrosis expanded by<br />
chronic inflammation containing macrophages (some <strong>of</strong> them containing hemosiderin),<br />
lymphocytes and plasma cells.
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