BIOGRAPHICAL SKETCHNAMEK. Mark AnseleRA COMMONS USER NAMEanselmPOSITION TITLEAssistant Pr<strong>of</strong>essor <strong>of</strong> Microbiology andImmunologyEDUCATION/TRAININGINSTITUTION AND LOCATION DEGREE YEAR(s) FIELD OF STUDYVirginia Tech (Blacksburg, VA) B.S. 1992-1996 Biochemistry<strong>University</strong> <strong>of</strong> California, San Francisco Ph.D. 1996-2001 Biomedical SciencesImmune Disease Institute, Harvard Medical School 2001-2007 ImmunologyPositions2001 – 2005 Postdoctoral Fellow, Immune Disease Institute (p.k.a. <strong>Center</strong> for Blood<strong>Research</strong>), Harvard Medical School, Boston, MA2005 – 2007 Instructor, Department <strong>of</strong> Pediatrics, Children’s Hospital and ImmuneDisease Institute (p.k.a. <strong>Center</strong> for Blood <strong>Research</strong>), Harvard MedicalSchool, Boston, MA2008 – Present Assistant Pr<strong>of</strong>essor, Department <strong>of</strong> Microbiology and Immunology and<strong>Sandler</strong> <strong>Asthma</strong> <strong>Basic</strong> <strong>Research</strong> <strong>Center</strong>, <strong>University</strong> <strong>of</strong> California SanFranciscoOther Experience and Pr<strong>of</strong>essional Memberships1998 - American Association for the Advancement <strong>of</strong> Science2006 - American Association <strong>of</strong> Immunologists2007 - International Cytokine Society2011 - Board <strong>of</strong> Reviewing Editors, Science Signaling2011 - International Predoctoral Fellows Review Cmte.,Howard Hughes Medical Institute2012 - NIH peer review committee: Cellular & MolecularImmunology B, ad hoc reviewerAwards and Honors1997 – 2001 Howard Hughes Medical Institute Predoctoral Fellowship2001 – 2004 Damon Runyon Cancer <strong>Research</strong> Fund Postdoctoral Fellowship2005 – 2007 Leukemia and Lymphoma Society Special Fellow2006 Burroughs Wellcome Career Award in Biomedical Sciences97
2007 International Cytokine Society Outstanding Postdoctoral Fellow2009 Dana Foundation Human Immunology Scholar2012 American Association <strong>of</strong> Immunologists Young Investigator TravelAward2012 Leukemia & Lymphoma Society ScholarSelected Peer-reviewed Publications1. Grégory Seumois, Pandurangan Vijayanand, Christopher J Eisley, Nada Omran, LukasKalinke, Mai North, Asha P. Ganesan, Laura J Simpson, Nathan Hunkapiller, FleixMolzahan, Prescott G Woodruff, John V Fahy, David J Erle, Ratka Djukanovic, RobertBlelloch, K Mark Ansel: An integrated nano-scale approach to pr<strong>of</strong>ile miRNAs in limitedclinical samples. Am J Clin Exp Immuol. 1:70-89 (2012)2. Hoefig KP, Rath N, Heinz GA, Wolf C, Dameris J, Schepers A, Kremmer E, Ansel KM,Heissmeyer V. Eri1 degrades the stem-loop <strong>of</strong> oligouridylated histone mRNAs to inducereplication-dependent decay. Nat Struct Mol Biol. 20:73-81 (2013)3. Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, NguyenC, Barczak AJ, Zlock LT, Blaev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ,Woodruff PG. Airway Epithelial miRNA Expression is Altered in <strong>Asthma</strong>. Am. J. Respir.Crit. Care Med. 186:965-74 (2012)4. Thomas MF, Abdul-Wajid S, Panduro M, Babiarz JE, Rajaram M, Woodruff P, Lanier LL,Heissmeyer , Ansel KM. Eri1 regulates microRNA homeostasis and mouse lymphocytedevelopment and anti-viral fuction. Blood. 120:130-42 (2012)5. Vijayanand P, Seumois G, Simpson LJ, Abdual-Wajid S, Baumjohann D, Panduro M, HuangX, Interlandi J, Djuretic IM, Brown DR, Sharpe AH, Rao A, Ansel KM. Interleukin-4Productio y Follicular Helper T Cells Requires the Conserved Il4 Enhancer HypersensitivitySite V. Immunity 36:175-87 (2012)6. Baumjohann D, Okada T, Ansel KM. Cutting Edge: Distinct Waves <strong>of</strong> BCL6 Expressionduring T Follicular Helper Cell Development. J Immunol.187: 2089-92 (2011)7. Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R,Ansel KM. MicroRNA-29 Regulates T-Box Transcription Factors and Interferon-γProduction in Helper T Cells. Immunity 35:169-81 (2011)8. S<strong>of</strong>i MH, Qiao Y, Ansel KM, Kubo M, Chang CH. Induction and Maintenance <strong>of</strong> IL-4Expression Are Regulated Differently by the 3' Enhancer in CD4 T Cells. J. Immunol.186:2792-9 (2011)9. Thomas MF, Ansel KM. Construction <strong>of</strong> small RNA cDNA libraries for deep sequencing.Methods Mol Biol. 667:93-111 (2010)10. Parameswaran P, Sklan E, Wilkins C, Burgon T, Samuel MA, Lu R, Ansel KM, HeissmeyerV, Einav S, Jackson W, Doukas T, Paranjape S, Polacek C, Barreto dos Santos F, Jalili R,Babrzadeh F, Gharizadeh B, Grimm D, Kay M, Koike S, Sarnow P, Ronaghi M, Ding SW,Harris E, Chow M, Diamond MS, Kirkegaard K, Glenn JS, Fire AZ. Six RNA Viruses andForty-One Hosts: Viral Small RNAs and Modulation <strong>of</strong> Small RNA Repertoires inVertebrate and Invertebrate Systems. PLoS Pathog. 6:e1000764 (2010)98
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TABLE OF CONTENTSMission StatementO
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Overview - 2013Richard M. Locksley,
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effective July 2012, thus becoming
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an ongoing part of the mission. Thu
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manage that study in terms of recru
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Growth in accumulated extramural fu
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somatic hypermutation, and hence af
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Sandler Asthma Basic REsearch Cente
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Sandler Asthma Basic REsearch Cente
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Sandler Asthma Basic REsearch Cente
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Sandler Asthma Basic REsearch Cente
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Sandler Asthma Basic REsearch Cente
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Selected Publications1. Liu L, Yan
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Sandler Asthma Basic REsearch Cente
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- Page 91 and 92: BIOGRAPHICAL SKETCHNAMEChristopher
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34. Tang CH, Wei W, Hanes MA, Liu L
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BIOGRAPHICAL SKETCHNAMERichard M. L
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12. Reinhardt RL, H-E Liang, RM Loc
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21. Dickgreber N, KJ Farrand, N van
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BIOGRAPHICAL SKETCHNAMEWilliam E. S
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5. Ryan JC, Turck J, Niemi EC, Yoko
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BIOGRAPHICAL SKETCHNAMEDean Sheppar
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cells causes autoimmunity and colit
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Overall project goal: This is a tra
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4. Locksley, R.M., Reiner, S.J., Sa
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BIOGRAPHICAL SKETCHNAMEArthur Weiss
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Selected Peer-reviewed Publications
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A119632Weiss (PI)07/01/12-06/30/14A
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BIOGRAPHICAL SKETCHNAMEJonathan S.
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3. Ingolia NT, Ghaemmaghami S, Newm
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P50 GM102706-01 (Cate) 09/2012 - 08
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BIOGRAPHICAL SKETCHNAMEZena Werb, P
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1998 Rotschild/Mayent Fellowship, I
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Research SupportOngoingNIH/NCI R01
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BIOGRAPHICAL SKETCHNAMEPrescott Gur
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8. Choy DF, Modrek B, Abbas AR, Kum
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The major goals are to serve as a c