DONOR SELECTION FOR ALLOGENEIC STEM CELL ... - CBMTG
DONOR SELECTION FOR ALLOGENEIC STEM CELL ... - CBMTG
DONOR SELECTION FOR ALLOGENEIC STEM CELL ... - CBMTG
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SCT <strong>DONOR</strong> <strong>SELECTION</strong>Donor Gender/ParityGale (1987): Registry data looking at risk factorsfor aGVHD→ Parous/transfused donor/male recipient had RR (2.9)Flowers (1990): Parous donors had highest riskof aGVHD and lowest 5-yr survivalKollman (2001) and Lee (2007): In VUD-BMT MVanalysis, neither donor gender or parity affectedOAS – however, risk of grade III-IV acute andchronic GVHD in parous