Background and Significance

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Significance• Significance is related to both:• The clinical problem (i.e. the mortality ormorbidity caused by the problem that you willaddress).• The relevance of your potential findings beyondthe clinical problem (i.e. benefit of a newoperation for ASD to all Peds CT operations).• Amount of innovation (incremental change orparadigm shift).
Significance• The reviewer’s critique is required by theNIH to contain sections on significance andinnovation.• Write the significance and innovationsections so the reviewer doesn’t have to.
Page 1 and 2: NIH Grantsmanship: Backgroundand Si
Page 3 and 4: General Comments• Find out in adv
Page 5 and 6: A typical study section
Page 7 and 8: FontUse an Arial, Helvetica, Palati
Page 9 and 10: Formatting of Paragraphs• 1 main
Page 11: Pictures, Figures and Cartoons•
Page 14 and 15: B. Background and SignificanceBrief
Page 16 and 17: Background• Use this section to s
Page 18 and 19: Background and Significance:Organiz
Page 22: AHA Fatal Flaws• Problems with si

Background and Significance

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