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Clinical Pathology, 105 RI3601 West 13 Mile RoadRoyal Oak, MI 48073-676922 nd Annual Symposium onMolecular PathologyClinical Applications ofGenomic MedicineSept. 25 – 26, 2013Somerset Inn • Troy, Michiganwww.beaumont.edu/dnasymposiumP8956Re1_10628_05281322 ndANNUAL SYMPOSIUMON MOLECULAR PATHOLOGYClinical Applications ofGenomic MedicineSept. 25 – 26, 2013Somerset Inn, Troy, Michiganwww.beaumont.edu/dnasymposiumClinical Applications ofGenomic MedicineWe are pleased to present the <strong>Beaumont</strong> HealthSystem 22nd Annual Molecular PathologySymposium on Clinical Applications of GenomicMedicine. This year’s symposium will again beheld at the beautiful Somerset Inn in Troy, Mich.Highlights of this year’s meeting include HotTopics in Molecular Medicine on Wednesdaymorning and Molecular Hematology onWednesday afternoon. On Thursday, themorning session is on Molecular Oncologyand the afternoon session is on MolecularMicrobiology.The symposium provides significant opportunitiesfor professional education, networking andresource building for registrants. You shouldstrongly consider attending if you are involvedin molecular diagnostics or are interested inlearning about this fast-paced specialty of clinicallaboratory science. We are pleased to bring youthese excellent educational opportunities atmodest registration fees, thanks to ourcommercial exhibitors.Lunch will be provided with each day’sregistration fee. In addition, there will be a wineand cheese reception at the close of Wednesday’ssession. An exhibit area will be open where youcan learn of new products and services that areavailable to enhance laboratory operations frommolecular-specific vendors.We hope you will make the time to join us.Target audienceWhile all <strong>physicians</strong> and health care professionalsare invited, this year’s program is focused on thepractices of Hematology, Oncology, InfectiousDiseases, Internal Medicine and Pathology.Sponsoring institutionThis symposium is sponsored by the Departmentof Pathology and Laboratory Medicine,<strong>Beaumont</strong> Health System, Royal Oak, Mich.ObjectivesUpon completion of this conference,attendees can expect to achieve thefollowing overall objectives:• assess advanced methods employed forclinical molecular testing• employ new technologies beingimplemented in Molecular Pathology• discuss pertinent and innovative aspectsof DNA technology related to clinicalapplications• identify important aspects of MolecularMedicine including hot topics, molecularbasedOncology and Hematology andMolecular Microbiology testing• appraise future considerations andissues based on research activities andclinical needsAccreditation and creditAccreditation: William <strong>Beaumont</strong> Hospital isaccredited by the Accreditation Council forContinuing Medical Education (ACCME)to provide continuing medical educationfor <strong>physicians</strong>.Credit: William <strong>Beaumont</strong> Hospitaldesignates this live activity for a maximumof 10.75 AMA PRA Category 1 Credits TM .Physicians should claim only the creditcommensurate with the extent of theirparticipation in the activity.(CME Credit breakdown: Wednesday 5.25;Thursday 5.5).Disclosure informationAll speakers have been asked to discloseany relevant relationships they may havewith commercial companies. The presenceor absence of relationships (as well asoff-label discussion of products) will bedisclosed at the time of the meeting.


22 nd Annual Symposium on Molecular Pathology • Clinical Applications of Genomic MedicineSymposium location andhotel accommodationsSomerset Inn2601 West Big Beaver RoadTroy, MI 48084Toll free:...........800-228-8769Phone:.............248-643-7800Fax: ................248-643-2296Web site: ...........www.somersetinn.comRegistration will be held in the SomersetBallroom foyer (located inside the northentrance). Registration hours are:Wednesday .......7:30 a.m. – 5 p.m.Thursday ..........7:30 a.m. – 12 p.m.Free parking is available at the Somerset Inn.For driving instructions, please check thewebsite above.Rooms are being held for symposiumparticipants until Sept. 20, 2013.Tower Executive WingSingles $99* $119*Doubles $99* $119**Add 13.3% taxPlease state “<strong>Beaumont</strong> MolecularPathology Symposium” when makingreservations.Ground transportation• Sedan service from/to the airport to/fromSomerset Inn is available through:– Trinity Shuttle Service:888-789-6187 ($140/one way [up to 10people] $270 round trip)– Metro Car:800-456-1701 ($92 one wayincludes tip)– Metro Connection:866-715-8662 ($70 one way)Prices were quoted at the time of publicationand are subject to change at any time.FacultyMark Boguski, M.D., Ph.D.Beth Israel Deaconess Medical Center/Harvard MedicalSchool, Boston, Mass.David S. Bosler, M.D.Cleveland Clinic, Cleveland, OhioMary E. Brandt, Ph.D.Centers for Disease Control and Prevention, Atlanta, GeorgiaRichard Burack, M.D., Ph.D.University of Rochester Medical Center School of Medicineand Dentistry, Rochester, N.Y.Michael B. Chancellor, M.D.<strong>Beaumont</strong> Health System, Royal Oak; OaklandUniversity William <strong>Beaumont</strong> (OUWB) School ofMedicine, Rochester Hills, Mich.Jonathan L. Curry, M.D.MD Anderson Cancer Center, Houston, TexasAndrew L. Feldman, M.D.Mayo Clinic, Rochester, Minn.Gopakumar Iyer, M.D.Memorial Sloan-Kettering Cancer Center,New York City, N.Y.Michael Loeffelholz, Ph.D., D(ABMM)University of Texas, Galveston, TexasAnurag Malani, M.D.St. Joseph Mercy Health System, Ann Arbor, Mich.Mark Micale, Ph.D., FACMG<strong>Beaumont</strong> Health System, Royal Oak; OUWB School ofMedicine, Rochester Hills, Mich.Keyur P. Patel, M.D., Ph.D.MD Anderson Cancer Center, Houston, TexasJohn A. Stamatoyannopoulos, M.D.University of Washington School of Medicine,Seattle, Wash.Planning committeeDepartment of Clinical Pathology<strong>Beaumont</strong> Hospital, Royal Oak, Mich.Mark Kolins, M.D., FACPEDomnita Crisan, M.D., Ph.D., HCLDMitual Amin, M.D.Anne Marie Blenc, M.D.Bobby L. Boyanton, Jr., M.D.Neng Chen, Ph.D., FACMGVonda Douglas-Nikitin, M.D.James Huang, M.D.Mark Micale, Ph.D., FACMGGabriel Maine, Ph.D.Peter A. Millward, M.D.Barbara Robinson-Dunn, Ph.D., D(ABMM)Marc Smith, M.D.Michele L. Cox, M.S.John Gibson, M.S.Marcy King, B.S.Nancy Ramirez, M.S.Jessica Rice, B.S.SchedulePresentation handouts will be available for download and printfrom website one week prior to the symposium.Wednesday, Sept. 257:30 a.m. Registration and continental breakfastHot Topics in Molecular MedicineModerator: Mark Micale, Ph.D., Director, Cytogenomics,<strong>Beaumont</strong> Health System8 a.m. The Diagnostic and Prognostic Implications ofDetecting Genomically Complex Abnormalitiesin Hematolymphoid Disorders Using High-Resolution Chromosome ArraysMark Micale, Ph.D., FACMG<strong>Beaumont</strong> Health SystemOUWB School of Medicine, Rochester Hills, Mich.8:45 a.m. Pathology and the Third Wave ofMedical GenomicsMark Boguski, M.D., Ph.D.Beth Israel Deaconess Medical Center/Harvard MedicalSchool, Boston, Mass.9:30 a.m. Break10 a.m. Stem Cell Research in the Urinary Tract:Discovery Science to Phase III TrialMichael B. Chancellor, M.D.<strong>Beaumont</strong> Health SystemOUWB School of Medicine, Rochester Hills, Mich.11 a.m. – 1 p.m. Corporate Workshops*11:45 a.m. – 12 p.m. Pick up box lunchMolecular HematologyModerators: Domnita Crisan, M.D., Ph.D., Director, MolecularPathology, <strong>Beaumont</strong> Health System, and James Huang, M.D.,Associate Director of Flow Cytometry, <strong>Beaumont</strong> Health System1 p.m. Next Generation Sequencing in Leukemia:From Discovery to Clinical CareKeyur P. Patel, M.D., Ph.D.MD Anderson Cancer Center, Houston, Texas1:45 p.m. Targeted Therapy in HematolymphoidMalignanciesDavid S. Bosler, M.D.Cleveland Clinic, Cleveland, Ohio2:30 p.m. Break3 p.m. Practical Application of Molecular Assays forB-Cell Clonality: Biomed-2 and BeyondRichard Burack, M.D., Ph.D.University of Rochester Medical Center School of Medicineand Dentistry, Rochester, N.Y.3:45 p.m. Update on Genetics of T-Cell LymphomasAndrew L. Feldman, M.D.Mayo Clinic, Rochester, Minn.4:30 p.m. Wine and cheese receptionCorporate exhibits open until 6 p.m.Thursday, Sept. 267:30 a.m. Registration and continental breakfastMolecular OncologyModerators: Mitual Amin, M.D., Director of Advanced Diagnosticsand Immunohistochemistry, <strong>Beaumont</strong> Health System, and MarkMicale, Ph.D., Director, Cytogenomics, <strong>Beaumont</strong> Health System8 a.m. KEYNOTE ADDRESS:From Chromatin to Common DiseasesJohn A. Stamatoyannopoulos, M.D.University of Washington School of MedicineSeattle, Wash.9 a.m. Break9:30 a.m. Harnessing Molecular Pathways in Cancer:A New Paradigm in Urothelial CarcinomaGopakumar Iyer, M.D.Memorial Sloan-Kettering Cancer Center, New York City, N.Y.10:15 a.m. Molecular Pathology of Cutaneous MelanomaJonathan Curry, M.D.MD Anderson Cancer Center, Houston, Texas11 a.m. – 1 p.m. Corporate Workshops*11:45 a.m. – 12 p.m. Pick up box lunchMolecular MicrobiologyModerators: Bobby Boyanton Jr., M.D., Medical Director, andBarbara Robinson-Dunn, Ph.D., Technical Director, Microbiology,<strong>Beaumont</strong> Health System1 p.m. Fungal Infections Related to ContaminatedSteroid InjectionsAnurag Malani, M.D.St. Joseph Mercy Health System, Ann Arbor, Mich.2 p.m. Break2:30 p.m. Multistate Outbreak of Fungal Meningitis andOther Infections: Development of DiagnosticTesting in a Large Outbreak SituationMary E. Brandt, Ph.D.Centers for Disease Control, Atlanta, Ga.3:30 p.m. Pitfalls in the Validation of Molecular Assaysfor Bordetella pertussisMichael Loeffelholz, Ph.D., D(ABMM)University of Texas, Galveston, Texas4:30 p.m. Symposium ends*Lunch Workshops: The corporate workshops arenot endorsed by William <strong>Beaumont</strong> Hospital andare not part of the CME activity.22 nd Annual Symposium on Molecular PathologyRegistration formName/degree/credentials__________________________________________________________________________________________________Department_______________________________________________Institution__________________________________________________Street address____________________________________________________________________________________________________________City____________________________________________________________________________________________________________________State/Province____________________________________ ZIP________________________ Country_________________________________Phone___________________________________ Fax ________________________________________ Email___________________________________________FeesThe registration fee includes a continentalbreakfast, box lunch and breakrefreshments. Wednesday’s registration alsoincludes wine and cheese reception.Full symposium(Wednesday and Thursday)Physicians,bioscientists, Ph.D.s,other scientific/research staffFellows, residents,technologists, otherCheck appropriate boxes<strong>Beaumont</strong> HealthSystem employees$150 $75 $50Wednesday only $80 $40 $25Thursday only $80 $40 $25To register online, visit our website at: www.beaumont.edu/dnasymposium.Registrations must be received by September 20, 2013. After Sept. 20, registrations will only be acceptedonsite, at the meeting’s registration desk, on a space-available basis. For help with registration, contactRita Najjar at 248-551-6269, or email at rnajjar@beaumont.edu.Refunds, less a $25 processing fee, will be honored on or before Sept. 20, 2013. After Sept. 20, 2013,no refunds will be issued; however substitutions are permitted. To cancel your registration please sendan email to rnajjar@beaumont.edu and include “Conference Cancellation” in the subject line.To register:√ Online at www.beaumont.edu/dnasymposiumCredit card paymentClick on Registration; you will be directed to CME tracker website√ Mail check payment to: <strong>Beaumont</strong> Health SystemRita NajjarCME, 112ABW3601 West 13 Mile RoadRoyal Oak, MI 48073-6769

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