A Clinical Study to Evaluate the Effect of Extract Based ... - IJGHC

A Clinical...Satish Agrawal and Hemant PolTable- 1: Drug compositionGuduchi stem-100mgSarphgandha root-50mgJatamansi rhizome-100mgPunarnava root-50mgShilajeet-75mgAjwain seeds-50mgNishotha root-50mgPippali fruit-25mgStandard control (active comparator) capsule contains 500 mg Ghana of Sarpagandha root.RESEARCH METHODOLOGYType of study: Single blinded comparative study.Study site: IPD and OPD department of Shubhdeep ayurved medical college, Indore (MP).Sample size: 50 patients divided randomly into two equal groups. Group A given trial drug whereas GroupB given control drug.Drug dosage and vehicle: 1 capsule twice daily with lukewarm water after meals.Duration of treatment: one month (examined at weekly intervals.)Dietary advice: To strictly restrict the daily intake of sour (amla), salty (lavana) and heavy (guru) diet.OBSERVATIONS &RESULTS• 70% Patients found to be hypertensive were above 40 years of age.• 60% Patients were fond of salty & spicy diet.• Out of 50 patients 30 patients (60%) belongs to service class.• Out of 50 patients, 35 patients (70%) were male.• Regarding prevalence of symptoms, Dyspnoea on routine work was found in 82%,Headache & palpitation in 80%, Vertigo in 78% & Fatigue in 66% patients.Table- 2: Paired‘t’ Test for Subjective parameters – group AS.No. Symptom N B.T. A.T. Diff. % SD SE ± ‘t’ PMean Mean Mean Relief1 Headache 20 1.65 0.5 1.15 69.69 0.587 0.131 8.76