A Clinical Study to Evaluate the Effect of Extract Based ... - IJGHC

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A Clinical...Satish Agrawal and Hemant PolThe trial drug is supposed to have specific effect on circulatory and nervous system so as to relieve thepathogenesis of hypertension. Ajwain 4 and Pippali 5 pacify Kapha deposited on vessel wall and seem towork on Sanchaya, Prakopa and Prasara stage of Kriyakala. Shilajeet 6 and Pippali exerts Srotoshodhanakarma through Rasayana property and seems to work on Sthana sanshraya stage to curette the Kaphadeposited on vessel wall. It is evident that this stage occurs at the site of disease. Punarnava 7 andNishotha 8 exert diuretic action through Shothhara karma. Guduchi 9 helps in pacifying remaining Dosha.Jatamansi 10 and Sarpgandha 11 together help to reduce sympathetic hyperactivity and nervous factorsresponsible for hypertension. In other words they exert Manodoshhara karma. It has been proved bymodern researches also.Finally it can be concluded that the drug under study has shown enthusiastic results in reducing the overallvalue of blood pressure. 64% patients got effectively cured, 24% got well cured and 12% got fairly cured.Regarding symptomatic relief, out of 25 patients 8 showed more than 75% relief, 9 showed more than50% relief , 7 showed more than25% relief and only 1 patient showed less than 25% relief in overallsymptoms (Table 9). No significant side effects have been reported in any subject.To conclude, the drug under trial has shown highly promising results in treating hypertension, whichshould be assessed on larger population. It has also opened the way for treatment of other disease entitywhich is result of undisciplined dietary and daily regimen of modern society.ACKNOWLEDGEMENTWe greatly acknowledge respected Principal, hospital staff & our colleagues, Shubhdeep AyurvedMedical College & hospital Indore for extending their every possible help & well wishes tocomplete the above study.REFERENCES1. Brahman Tripathi, Charak Samhita (vol-1), Sutrasthana, Trishothiya Adhyay, Shloka no. 18/44,Varanasi Chaukhambha Surbharati Prakashan, 2009, page 378.2. Brahman Tripathi , Charak Samhita (vol-2), Chikitsasthana, Vatvyadhi Adhyay, Shloka no. 28/59,Varanasi Chaukhambha Surbharati Prakashan, 2009, page 948.3. Brahman Tripathi , Charak Samhita (vol-1), Sutrasthana, Dirghamjivitiya Adhyay, Shloka no.1/66, Varanasi Chaukhambha Surbharati Prakashan, 2009, page 36.4. Dr. K.C. Chunekar, commentary edited by G.S. Pandey, Bhavaprakash Nighantu HaritkyadiVarga, Shloka 76, Varanasi Chaukhambha Bharati Academy, reprint 2004, page 25.5. Dr. K.C. Chunekar, commentary edited by G.S. Pandey, Bhavaprakash Nighantu HaritkyadiVarga, Shloka 58, Varanasi Chaukhambha Bharati Academy, reprint 2004, page 15.6. Indradev Tripathi, Raj Nighantu Guduchyadi , Varga Shloka 73, Varanasi, ChaukhambaKrishnadas Academy, 2003, page 433.7. Dr. K.C. Chunekar, commentary edited by G.S. Pandey, Bhavaprakash Nighantu GuduchyadiVarga, Shloka 231, Varanasi Chaukhambha Bharati Academy, reprint 2004, page 422.379 IJGHC; 2012, Vol.1, No.3, 374-380.
A Clinical...Satish Agrawal and Hemant Pol8. Dr. K.C. Chunekar, commentary edited by G.S. Pandey, Bhavaprakash Nighantu GuduchyadiVarga, Shloka 194, Varanasi Chaukhambha Bharati Academy, reprint 2004, page 397.9. Indradev Tripathi, Raj Nighantu Guduchyadi, Varga Shloka 17-18, Varanasi, ChaukhambaKrishnadas Academy, 2003, page 31.10. Database on Medicinal plants used in Ayurveda, Volume 7 CCRAS, New Delhi, 2005, p136-139.11. Database on Medicinal plants used in Ayurveda, Volume 7 CCRAS, New Delhi, 2005, p387- 390.*Correspondence Author: Dr Satish Agrawal; Associate professor,Department of Kayachikitsa , Shubhdeep Ayurved Medical College & Hospital,Khandwa Road, Indore -452020380 IJGHC; 2012, Vol.1, No.3, 374-380.
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