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Syllabus Spring 2012CHE 546 Nuclear Magnetic Resonance Spectroscopy1 to 3 creditsTu Th 9:30-10:50A LSC 215Dr. Philip Borer Office: 0-221C Sci Tech pnborer@syr.eduDr. Deborah Kerwood Office: 0-222D Sci Tech djkerwoo@syr.eduStudents may register in M001 alone, which is the pre-requisite for M002. M003 is strongly recommended forthose taking M002 (M002 is the co-requisite for M003).Section M001: 1 credit, 17-Jan to 21-Feb, basic principles of spectroscopy, nuclear spins, ensembles, coupling,one-dimensional Fourier Transform NMR, spin relaxation and NOE.Section M002: 1 credit, 28-Feb to 1-May, Classical and quantum descriptions of nuclear spins, density andproduct operators, two-dimensional NMR, coherence selection, heteronuclear correlations and multidimensionalNMR.Section M003: 1 credit, 16-Feb to 1-Mar, 1D NMR data processing, 5-Apr to 12-Apr, 2D NMR dataprocessing.Prerequisites:(1) Two semesters of calculus-based physics,(2) Organic chemistry with an introduction to NMR (CHE 325/335) or equivalent experience,(3) Physical chemistry that includes an introduction to quantum mechanics.Required Text: Purchase from SU bookstore, Amazon.com, or equivalent online store. The first reading assignment(Pochapsky, chapter 1, pp. 1-10) should be completed before the first lecture. If ordering online,purchase the required text immediately to prevent possible delays in delivery.Thomas C. Pochapsky and Susan Sondej Pochapsky, NMR for Physical and Biological Scientists (2007)ISBN 08153-4103-2. Taylor & Francis Group, New York, NYamazon.com $94.00http://www.amazon.com/Physical-Biological-Scientists-Thomas-Pochapsky/dp/0815341032/ref=sr_1_1?ie=UTF8&qid=1321571132&sr=8-1Recommended Text: A second text is strongly recommended to give additional perspective on multidimensionalNMR. Contact Dr. Borer or Dr. Kerwood if you have a book that you think is sufficient. Otherwise, werecommend the following text, which has very useful animations for understanding spin physics:Steven M. Pascal, NMR Primer: An HSQC-based Approach with Vector Animations (2008) ISBN 978-1901019-08-7. IM Publications LLP, Chichester, UKamazon.com $35.00http://www.amazon.com/NMR-Primer-HSQC-based-Steven-Pascal/dp/190101908X/ref=sr_1_1?s=books&ie=UTF8&qid=1321571268&sr=1-1The Syracuse University Academic Integrity Policy holds students accountable for the integrity of the workthey submit. Students should be familiar with the Policy and know that it is their responsibility to learn aboutinstructor and general academic expectations with regard to proper citation of sources in written work. The policyalso governs the integrity of work submitted in exams and assignments as well as the veracity of signatureson attendance sheets and other verifications of participation in class activities. Serious sanctions can resultfrom academic dishonesty of any sort. For more information and the complete policy, seehttp://supolicies.syr.edu/ethics/acad_integrity.htm.If you believe that you need accommodations for a disability, please contact the Office of Disability Services(ODS), http://disabilityservices.syr.edu, located at 804 University Avenue, room 309, or call (315) 443-4498for an appointment to discuss your needs and the process for requesting accommodations. ODS is responsiblefor coordinating disability-related accommodations and will issue students with documented disabilities "AccommodationAuthorization Letters." as appropriate. As accommodations may require early planning and generallyare not provided retroactively, please contact ODS as soon as possible.

TENTATIVE SCHEDULE FOR CHE 546Prof. Philip N. Borer pnborer@syr.edu0-221 Sci Tech 443 5925Dr. Deb Kerwood djkerwoo@syr.edu0-222 Sci Tech 443 5932Period DateTopic, Notes Pochapsky Pascal1 Tu 17-Jan Ch. 1, Spectroscopy 1 - 102 Th 19-Jan 11 - 203 Tu 24-Jan Ch. 2, Spins, Ensembles, Coupling 23 - 34 1.1-1.64 Th 26-Jan 35 - 46 3.1-3.25 Tu 31-Jan Ch. 3, Fourier Transform NMR (1D) 49 - 60 1.66 Th 2-Feb 61 - 737 Tu 7-Feb 74 - 888 Th 9-Feb Ch. 4, Spin relaxation and NOE 95 - 103 2.1-2.59 Tu 14-Feb 104 - 11310 Th 16-Feb Intro to SpinWorks Lab11 Tu 21-Feb Final M001 Lecture 114 - 12012 Th 23-Feb 1D acquisition and processing Lab13 Tu 28-Feb Ch. 5, Classical and Quantum Descriptions 123 - 13214 Th 1-Mar 1D acquisition and processing Lab15 Tu 6-Mar 133 - 14416 Th 8-Mar Ch. 6, Density and Product Operators 147 - 156 3.4-- Tu 13-Mar Spring Break---- Th 15-Mar Spring Break--17 Tu 20-Mar 157 - 16318 Th 22-Mar Ch. 7, 2D NMR, Coherence selection 167 - 17919 Tu 27-Mar 180 - 18920 Th 29-Mar 190 - 199 4.4-4.621 Tu 3-Apr 200 - 20822 Th 5-Apr 2D Acquisition and Processing Lab23 Tu 10-Apr Ch. 8, Heteronuclear correlations 215 - 223 3.1-3.824 Th 12-Apr 2D Acquisition and Processing Lab25 Tu 17-Apr 224 - 230 4.1-4.326 Th 19-Apr 231 - 23827 Tu 24-Apr Ch. 9, Multidimensional NMR 241 - 251 5.1-6.428 Th 26-Apr 251 - 26229 Tu 1-May 262 - 271