Confined Production Processes for Non-Food Corn - Seed Science ...

A necessary first step in the project that BIGMAPscientists have undertaken is the development of a setof reliable, relevant, and representative good practicestandards for levels of confinement that are consistentwith current regulatory expectations. This descriptionof BIGMAP good practices was developed by a diverseteam of experts from within the university communitywho have offered their unique talents and expertiseto develop consensus good practices for the confinedfield production of corn expressing pharmaceuticalor industrial compounds. We thank the followingindividuals for their contributions to this exercise:Bruce Babcock (meteorology)Alicia Carriquiry (statistics)Joseph Cortes (process management)Karin Doorman (statistics)Dermot Hayes (public perception, economics)Adelaida Harries (regulations)Charlie Hurburgh (grain harvesting and distribution)Scott Hurd (risk assessment)Larry Johnson (processing)Kendall Lamkey (genetics)Bob Peterson (risk assessment)Kan Wang (plant transformation)Mark Westgate (pollen flow, agronomics)FIGURE 1: BIGMAP PMP AND PMI CORN OBJECTIVES1) Differentiate unintended presence issues in seed fromthose in grain;2) Develop quantitative information describing outflows tograin and seed;3) Categorize active substances based on the hazard thatthey present,4) Describe risk for categories of substances; and5) Suggest confinement procedures tailored to fitclasses of substances.We thank Melissa Swanson for her contributionto the flowcharts.In addition, we thank the following reviewers,not directly associated with BIGMAP:Gregory Jaffe, Center for Science in Public InterestNeil Hoffman, USDA–APHIS–BRSWilliam Horan, Horan Bros. Ag EnterprisesThomas Nickson, MonsantoDaryl RollandAlthough we highly valued the suggestions made by theseindividuals, the final product cannot conform entirely totheir suggestions, and we assume responsibility for allpositions taken.Prefaces and Acknowledgments 3