NAME Selsby, Joshua Taylor POSITION TITLE Assistant Professor ...

NAMESelsby, Joshua TaylorPOSITION TITLEAssistant ProfessoreRA COMMONS USER NAME (credential, e.g.,agency login) jtselsbyEDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such asnursing, and include postdoctoral training.)INSTITUTION AND LOCATIONDEGREE(if YEAR(s) FIELD OF STUDYapplicable)College of Wooster, Wooster, OH BA 1999 BiologyThe Ohio State University, Columbus, OH MA 2001 Exercise PhysiologyUniversity of Florida PhD 2005 Exercise PhysiologyUniversity of Pennsylvania Post doc 2005-2008 Muscle PhysiologyA. Positions and Honors.Positions and Employment1999-2001 Graduate Student Teaching Assistant, Exercise Physiology Section, The Ohio State University2001-2003 Graduate Student Teaching Assistant, Department of Applied Physiology and Kinesiology,University of Florida2003-2005 Graduate Student Research Assistant, Department Applied Physiology and Kinesiology,University of Florida2005-2008 Postdoctoral Fellow, Department of Physiology, University of Pennsylvania2008- Assistant Professor, Department of Animal Science, Iowa State UniversityOther Experiences and Professional Memberships2000-2001 Student member Midwest American College of Sports Medicine2001-2003 Student member Southeast American College of Sports Medicine2000-2002 Student member American College of Sports Medicine2004-2005 American Society for Gravitational and Space Biology2002- American Physiological SocietyHonors1995-1999 Achievement Award, College of Wooster1995-1999 Academic Achievement Award, College of Wooster, 1995-19992001 First runner up in Edward F. Hayes Graduate Research Forum, The Ohio State University2001 LaPradd Fellow, University of Florida2004 First runner up in The American Society for Gravitational and Space Biology graduate studentposter competition2006 Peter B. Weisman Fellow, Parent Project Muscular Dystrophy2007 NRSA Fellow, NIHB. Selected peer-reviewed publication (in chronological order)Selsby, JT, Beckett, KD, Kern, M and Devor, ST. Swim performance following creatine supplementation inDivision III athletes. Journal of Strength and Conditioning Research 17:421-424, 2003.Selsby, JT, DiSilvestro, R, and Devor, ST. A novel Mg-creatine chelate and a low dose creatinesupplementation regimen improve work. Journal of Strength and Conditioning Research 18:311-315, 2004.Selsby, JT, Judge, AR, Yimlamai, T, Leeuwenburgh, C, and Dodd, SL. Life long calorie restriction increasesheat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats. Experimental Gerontology40:37-42, 2005.Selsby, JT and Dodd, SL. Heat treatment reduces oxidative stress and protects muscle mass duringimmobilization. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology289(1):R134-139, 2005.

Dodd, SL, Selsby, JT, Payne, A, Judge, AR and Dott, C. Effects of Botulinum Neurotoxin type A (Dysport) onrat skeletal muscle myosin heavy chain composition. Toxicon 46:196-203, 2005.Sellman, JE, Deruisseau, KC, Betters, JL, Lira, VA, Soltow, QA, Selsby, JT, and Criswell, DS. In vivoinhibition of nitric oxide synthase impairs up-regulation of contractile protein mRNA in overloaded plantarismuscle. Journal of Applied Physiology 100:196-203, 2006.Pipinos, II, Judge, AR, Zhu, Z, Selsby, JT, Swason, S, Johanning, J, Baxter, B, Lynch, T, and Dodd, SL.Mitochondrial defects and oxidative damage in skeletal muscle of patients with peripheral arterial disease.Free Radical Biology and Medicine 41:262-269, 2006.Selsby, JT, Rother, S, Tsuda, S, Pracash, O, Quindry, J, and Dodd, SL. Intermittent hyperthermia enhancesskeletal muscle regrowth and attenuates oxidative damage following reloading. Journal of Applied Physiology102:1702-1707, 2007.Pipinos II, Judge AR, Selsby JT, Zhu Z, Swanson SA, Nella, A, and Dodd SL. The myopathy of peripheralarterial occlusive disease: Part 1. Functional and histomorphological changes and evidence for mitochondrialdysfunction. Invited review: Vascular and Endovascular Surgery 41:481-489, 2008.Judge, AR, Selsby, JT, and Dodd, SL. Antioxidants attenuate oxidative damage in skeletal muscle during mildischemia. Experimental Physiology. 93:479-485, 2008.Pipinos II, Judge AR, Selsby JT, Zhu Z, Swanson SA, Nella AA, Dodd SL. The myopathy of peripheral arterialocclusive disease: Part 2. Oxidative stress, neuropathy, and shift in muscle fiber type. Invited review: Vascularand Endovascular Surgery. 42:101-112, 2008.DiSilvestro RA, Selsby JT, and Siefker K. A Pilot Study of Copper Supplementation Effects on Plasma F 2αIsoprostanes and Urinary Collagen Crosslinks in Young Adult Women. Journal of Trace Elements in Medicineand Biology. 24, 165-168, 2010.Quindry J, French J, Hamilton K, Lee, Y Selsby JT, and Powers S. Exercise does not increasecyclooxygenase-2 myocardial levels in young or senescent hearts. The Journal of Physiological Sciences. 60,181-6, 2010.Gesing LM, Johnson AK, Selsby JT, Feuerbach C, Hill H, Faga M, Whiley A, Bailey R, Stalder KJ, and RitterMJ. Effects of pre-sorting prior to loading on stress responses at loading and unloading and transport lossesfrom market weight pigs. Professional Animal Scientist. 26:603-610, 2010.Morine, KJ, Bish, LT, Selsby JT, Gazzara JA, Pendrak K., Sleeper, MM, Barton ER, and Sweeney H.L.Activin IIB receptor blockade attenuated dystrophin pathology in a mouse model of Duchenne musculardystrophy. Muscle and Nerve. 42:722-730, 2010.Selsby JT, Pendrak K, Zadel M, Tian Z, Pham J, Carver T, Acosta P, Barton ER, and Sweeney HL. Leupeptinbased inhibitors do not improve the mdx phenotype. American Journal of Physiology – Regulatory, Integrative,and Comparative Physiology. 299:1192-1201, 2010.Morris CA*, Selsby JT*, Morris LD, Pendrak K, and Sweeney HL. Bowman Birk inhibitor attenuates dystrophicpathology in mdx mice. Journal of Applied Physiology. 109:1492-1499, 2010.* indicates that authors contributed equally to this work.Selsby JT. Increased catalase expression improves muscle function in mdx mice. Experimental Physiology.96.2:194-202, 2011.

C. Research SupportOngoing Research SupportDepartmental Start-Up Grant, Iowa State University Selsby (PI) 8/1/2008-PresentResearch Initiation FundsThe purpose of this funding is to set up the PI’s laboratory and fund preliminary studies needed to becompetitive for extramural research support.Role: PIUSDA Baumgard (PI) 1/1/2011-12/31/2016The physiological impact of heat stress on pig metabolism and performanceThe purpose of this grant is to determine the extent to which chronic and acute heat stress alter normalphysiology.Role: Co-investigatorR21 RR030232 NIH NCRR Ross (PI) 2/1/2010-1/31/2012Development of a novel porcine model of Duchenne muscular dystrophyOur goal for this project is to develop and perform the initial characterization of a porcine model for DMD.Role: Co-investigatorIowa Pork Producers Association Gabler (PI) 9/2010-9/2011Evaluating the contribution of ion pumps and protein turnover towards feed efficiency in finisher pigs selectedfor low and high residual feed intakeIn this project we will determine the extent to which changes in mTOR signaling, protein degradation, and ionpump activity are responsible for enhanced muscle growth in a high efficiency pig line.Role: Co-investigatorNutritional and Wellness Research Center (Martin Fund) Selsby (PI) 8/1/2010-7/31/2011The effect of quercetin on the progression of Duchenne muscular dystrophyIn this project we will collect preliminary data that contributes toward a determination of the extent to which thedietary supplement quercetin reduces muscle injury caused by dystrophin deficiency.Role: PICenter for Integrated Animal Genomics Selsby (PI) 7/1/2010-6/31/2011Use of dystrophin deficient mice to develop novel therapies for Duchenne muscular dystrophyThese funds help to support my animal colony.Role: PICompleted Research Support (Chronological)College of Wooster Copeland Memorial Fund Selsby (PI) 1998Swim performance following creatine supplementation in Division III athletesThe goal of this project was to determine if creatine would improve swimming performance.Role: PINational Football League Dodd (PI) 2004Can muscle heating attenuate atrophy caused by immobilization?The goal of this project was to determine if a heating regimen could attenuate atrophy caused by disuse. Thisproject was further by the inclusion of intermittent hyperthermia during reloading.Role: Co-InvestigatorNational Football League (competitive renewal) Dodd (PI) 2004Can muscle heating attenuate atrophy caused by immobilization?This was a competitive renewal for the project described below.Role: Co-Investigator

F32 AR 550052 NIH/NIAMS Selsby (PI) 6/1/2007-8/15/2008Does catalase expression improve the function of muscles from mdx and LGMD mice?The goal of this study was to determine if catalase over-expression would reduce dystrophic pathology inmouse models of Duchenne and limb girdle muscular dystrophies.Role: PI (H. Lee Sweeney, PhD, mentoring)Center for Integrated Animal Genomics Selsby (PI) 8/1/2008-6/30/2009What changes does PGC-1α treatment cause to dystrophic muscle?This is a small award intended to help fund pilot data collection directed toward the effect of PGC-1α ondystrophic skeletal muscle.Role: PICenter for Integrated Animal Genomics Selsby (PI) 8/1/2008-6/30/2009How does PGC-1α attenuate dystrophic pathology?These funds help to support my animal colony.Role: PI