ANIMAL TISSUE - Career Point

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CAREER POINT .Formation of RBC– Process of formation of RBC is called Erythropoiesis.– Organs which produce RBC's called Erythropoietic organs.– Hormone which stimulate Erthyropoiesis is called Erythropoietin synthesize by Kidney.– 1 st RBC is produced by yolk sac.– During embryonic life RBC are produced by Liver, Spleen, Placenta, Thymus gland.– In adult stage RBC is produced by RBM which filled in Trabeculae of spongy bones.– Kidney is an erthyropoietic organ in frog.Red Bone marrowMyeloid/Myelogenous TissueMyeloid cells (Stem cells)ModifiedPre-erythoblast cell (2n)MitosisErythroblastNucleus-PresentCell organelles-PresentStromatin-AbsentHaemoglobin-AbsentSize-Double than RBCErythroblastMaturationNucleus-AbsentCell organelles-AbsentStromatin-PresentHaemoglobin-DepositedSize-Double than RBCBy Vit. B 12 and folic acid.Normocyte [size same as RBC]ErythrocyteEnter into Blood.Corporate Office: CP Tower, IPIA, Road No.1, Kota (Raj.), Ph: 0744-3040000 (6 lines) ANIMAL TISSUE 34
– 1% RBC are destroyed daily but in same number new RBC are entered in the blood.– Destruction of RBC occur in spleen. So spleen is called Grave yard of RBC.– Spleen stores excess blood corpuscles so it is called Blood Bank of body.CAREER POINT .– In resting and slow flowing blood, the RBC form pile called Roulaux by adhering together due tosurface tension. Fibrinogen favours rouleaux condtion.– Minute bits of disintegrated red blood corpucles in known as Haemoconia– Ghost of RBC is made up of its plasma membrance.Table : Difference between different types of LeucocytesCharacter Lymphocytes Monocytes Eosinophils Basophils Neutophils(Acidophils)Number/percentageGranulesincytoplasmStaining ofcytoplasm20-25% 2-10% 2-3% 0.5-1% 60-65%Absent Absent Coarse Coarse FineBasophilic Basophilic Eosinophilic Basophilic NeutrophilicNucleus Rounded Bean-shaped Bilobed S-shaped3-lobedMultilobedSite ofFormationLymph nodes,spleen, thymus,tonsils, Peyer'spatches, BonemarrowBone marrow Bone marrow Bone marrow Bone marrowLife spanFew days oreven years10-20 hoursin the bloodtissue, monthsor even years4-8 hours inblood and 4 to5 days intissue4-8 hours inblood and 4to 5 days intissue4-8 hours inblood and 4 to5 days intissueFunctionAntibodyformationPhagocyticImportant rolein immunityanti-allergicSecretion ofheparin,histamineand serotoninPhagocyticCorporate Office: CP Tower, IPIA, Road No.1, Kota (Raj.), Ph: 0744-3040000 (6 lines) ANIMAL TISSUE 35
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Page 42 and 43: CAREER POINT .2. Conversion of Prot
Page 44 and 45: CAREER POINT .RH FACTOR- Discovered
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