Chemical Peels Catalog - Dermavista.com

professional use products

guarantee and assuranceFor over 20 years, Mediderma S.L. has specialized in and beendedicated to Professional Use Products, starting out withchemical peels (Sesglicopeel, Salipeel, Melaspeel, etc..), andleading up to the latest developments: liposomed peelings andcomplementary products.The key to our success over time has been based on:Our products, characterized as innovative, effective and safe.Our clients, health professionals, who have placed their trust inour products.Our own people, commercial technical support personnel,guaranteeing an adequate after-sales service of products.During this time, we have worked together toward a commongoal: improving service to our physicians and at the same timeimproving the quality of life of their patients. From now on, wewill continue down this path and begin a new journeyincorporating online tools in order to facilitate communicationbetween everyone involved: www.mediderm.comI wish to thank you all, who in some form or another have contributedto the creation of this catalogue, as with your knowledge it waspossible to include new products, services, facilities and benefits.Regards,Gabriel SerranoSES Group General Director

indexIntroduction to peelingsSesglicopeel· classic· S· K· KH· mascarillaMelaspeel· K· Kh· J· J2· R· GSalipeel· solution· ds· plus· ampoulesMandelac· solution· C· L· T· exfoliating gelAzelac· M· RU· peelArgipeel · LactipeelPyruvic peel· la· p· plusSpa peel· classic· lighteningNomenal fenol· light· medium· forte· kh· fdNomelan cafeico· step 0· light· forte· bleaching0506081012141516171820Retises· forte· spot peel· ct· 1%TCA· 15 %· 25 %· 35 %· 50 % crossGlycolic acid· 25 %· 50 %· 70 %Masks propimask· information· kojic· aha’s· aloe vera· bt· chitosan· daeses· endorphines· collagen booster· salicylic acid· vitamine c· youth booster· healingAdditives· glowing· antioxidant· resveraderm· bleaching mix· bleaching k· anti-acne· collagen booster I - II- III· lifting effectTreatment ampoules· glowing· reaffirming· anti-wrinkle· anti-couperosis· bleaching· purifyingSolutions· degreasing· sensyses· neutralizing22242526313537Therapeutic andcomplementary products· abradermol· mandelac scrub· rosoil ampoules· rosoil mask· hidraloe aloe gel· daeses lifting cream· btses anti-wrinkle cream· btses forte serum· nomelan c· post-treatment kitNanotech· introductionFerulac peel· classic· plus· nano additive mistSalipeel lic· lic· nano additive mistRetises nano· 1% nanopeel gel· 1% mistC-peel delivery serumNanomask· información· daeses· c-vit· aloe vera· collagen booster· youth booster· placenses· btsesNano meso solution· c-vit· daeses· retises· silorgses· placenses· seskavel mulberryGlossary384244454647495254

peeling | product | sesglicopeelsesglicopeelsesglicopeelclassicsesglicopeelSsesglicopeelKsesglicopeelKH100 ml - pH 2.0100 ml - pH 2.5100 ml - pH 2.5100 ml - pH 2.0COMPOSITIONCOMPOSITIONCOMPOSITIONCOMPOSITION· 52.5% Glycolic acid.· 20% Lactic acid.· 15% Glycolic acid.· 10% Salicylic acid.· 5% Citric acid.· 33% Glycolic acid.· 9% Lactic acid.· 7% Kojic acid.· 5% Citric acid.· 3% Salicylic acid.· Epilobium and Bearberry extracts.· 44% Glycolic acid.· 10% Citric acid.· 5% Kojic acid.· 3% Lactic acid.· 2% Hydroquinone.INDICATIONINDICATIONINDICATIONINDICATIONCutaneous aging.Preparatory chemical peel.Oily skin and /or acne prone skin(hormonal).Hyper keratolytic conditions(psoriasis, seborrheicdermatitis) and acne scars.Hyperpigmentations inhydroquinone sensitive patientsand patients with highphototypes.Inflammatory and noninflammatory acne, acne scars,rosacea and couperosis.Hyperpigmentations in lowphototype skins, and thosetolerant to hydroquinone.directionsAfter cleaning and degreasing the skin, and protecting sensitive areas, the peeling should be applied with a gauze, beginning in the moreresistant areas on the face and moving towards the most sensitive ones (forehead, cheeks, sub maxillary regions, chin, upper lip andnose).It should be applied quickly, in 15-20 seconds, and uniformly throughout the treatment area. In general it is recommended for 5 to 10minutes, or until the desired result has been reached, a light redness without frosting.After this time, to prevent the peeling from continuing to penetrate the skin, it must be neutralized by rinsing the application area withwater. After rinsing, to ensure that the product has been completely neutralized, a layer of neutralizing lotion can be applied.After the application, it is required to monitor the area for the unusual occurrence of hot or erythemic areas that require neutralization.If there are more than three areas, it is recommended to neutralize the entire peeling.During the application it is normal that the patient feels a slight tingling which disappears in a few minutes.06

sesglicopeel | product | peelingsesglicopeelProperties of glycolic acidGlycolic acid (GA) is one of the most used chemical substances in superficialchemical peelings.This AHA produces a variety of complete or partial alterations in the epidermisand papillary dermis.The procedure generates changes in the skin by stimulating epidermal proliferation,which destroys specific layers of altered skin or induces inflammatory reactionsnot well known.After several applications with this type of chemical peel, changes can be noticedin the skin such as new collagen deposits and the increase of GAGs in the papillarydermis, helping to repair cutaneous sun damage.Glycolic acid is very soluble in water and has a small molecule size. These twoqualities give it a greater trans-epidemic penetration. In some cases it can causeslight irritation after its application.sesglicopeelexfoliating mask100 ml - pH 2.5+ info- Tingling sensation (formulations with glycolic acid).- It is not necessary to wait to apply make up.- Applications of Tretinoin and Glycolic at 15-20% canbe resumed 72 hours later.- Does produce an intense peel (i.e. flaking skin).COMPOSITION· 30% Free glycolic acid.INDICATIONChemical Peel with a white clay masktexture (kaolinite) dry and mature skin.Abrasion of epidermic layers eliminatesimpurities and stimulates cellular turnover.directionsMask texture chemical peel:Apply a thin and uniform layer on the areato be treated, allow it to act for 5-10minutes and remove by rinsing theapplication area with water.07

peeling | product | melaspeelmelaspeelmelaspeelKmelaspeelKHmelaspeelJmelaspeelJ260 ml - pH 2.560 ml - pH 2.560 ml - pH 2.560 ml - pH 2.5COMPOSITIONCOMPOSITIONCOMPOSITIONCOMPOSITION· 14% Lactic acid.· 12% Citric acid.· 5% Kojic acid.· 2% Salicylic acid.· 10% Lactic acid.· 10% Citric acid.· 5% Kojic acid.· 2% Salicylic acid.· 2% Hydroquinone.· 14% Resorcinol.· 14% Salicylic acid.· 10% Lactic acid.· 2% Citric acid.· 25% Resorcinol.· 10% Lactic acid.· 8% Salicylic acid.· 5% Citric acid.INDICATIONINDICATIONINDICATIONINDICATIONHyperpignmetation in highphototype skins, or thosesensitive to hydroquinone.Active acne.Seborrheic dermatitis.Rosacea.Couperosis.Hyperpigmentations in lowphototype skin.Skins tolerant to hydroquinone.Active cystic acne and acnescars.Focal applications.Severe cystic acne.Lentiges, melasma and acnescars.modo de empleoApplication in layers. The application of this line of chemical peels is made layers. After the application of the first layer, it is necessary to waitabout 3 minutes to let the solution soak into the skin and dry. Afterwards, successive layers can be applied, observing the skin between applicationsto evaluate the degree of erythema and the presence or absence of whitening signs.Once the application is complete, it is necessary to seal the chemical peel with a slightly acidic light pH cream (Acglicolic classic cream gel orRetises CT yellow peel).Number of layers. It is recommended to start with 2 layers and increase the amount of layers in subsequent applications. Applying pressure orincreasing the amount of solution applied will increase the depth to which the solution penetrates.Because there is risk of inflammation, no more than 2 layers of solutions containing resorcinol should be applied to patients with dark complexions.Fitzpatrick skin types I and II can tolerate up to 5-6 solution layers.The application of the layers can be performed on an entire area or only on lesions. In this way, it is even possible to combine different solutions,using the less potent ones on the entire face and after focusing on lesions with focal layers of a more powerful solution.08

melaspeel | product | peelingmelaspeelJessner formulaAll chemical peels within this family have their origin in theJessner formula. They are characterized by theirhydroalcoholic based formula and contain a mixture of hydroxyacids (lactic acid, salicylic acid and citric acid) in theircomposition. All chemical peels in this line have a pH between2.0 and 2.5.+ infoMelaspeel Chemical peels have to be sealed with aslightly acidic light pH cream (Acglicolic Classic ForteCream, or Retises CT).melaspeelR60 ml - pH 2.5COMPOSITION· 14% Lactic acid.· 14% Resorcinol.· 5% Citric acid.· 5% Kojic acid.· 2% Salicylic acid.· 2% Hydroquinone.INDICATIONHyperpigmentations.Stronger formulation thanMelaspeel K and KH.melaspeelG60 ml - pH 2.5COMPOSITION· 14% Lactic acid.· 14% Salicylic acid.· 10% Glycolic acid· 2% Citric acid.INDICATIONCutaneous aging.peeling end pointThe application of these chemical peels produce a range of visual changes in the skin that are related to the depth reached by thechemical peels.LEVEL 1Very slight erythemaPseudo frostingMinimal peeling (1 or 2 days) or lack ofSkin tightnessLEVEL 2Bright red erythemaAreas of focal frostingModerate peeling (for 3-4 days)Burning sensation for a few minutesLEVEL 3Intense erythemaSignificant areas of frostingNoticeable scaling(over 8-10 days)Burning sensation for 15-30 minutesThe level of penetration is related to the preparation of the skin, the thickness of the stratum corneum, the sensitivity of the skin, thenumber of layers applied and the application form. It is generally required to apply one or two layers of a chemical peel to get to level1, two to four layers to get to level two, and four to six layers to get to level three.09

peeling | product | salipeelsalipeelsalipeelalcoholic solution60 ml - pH 2.0COMPOSITION· 25% Salicylic acid.salipeelds60 ml - pH 1.5COMPOSITION· 30% Salicylic acid.salipeelplus60 ml - pH 2.0COMPOSITION· 25% Salicylic acid.· 15% Azelaic acid.INDICATIONActive acne.Seborrheic Dermatitis.Rosacea.Couperosis.INDICATIONAcne and hyperkeratotic conditions.High phototype and sensitive skins.Formulated with a new medium (Macrogolpolyethylenglycol) making it suitable forall skin types, including most sensitive ones(dark skins).INDICATIONFolliculitis, acne, psoriasis...For skins accustomed to salicylic acid.Body treatments.directionsAfter cleaning and degreasing the skin and protecting sensitive areas,apply the chemical peel with a guaze starting from the sensitive areasof the face and moving to the most sensitive ones (forehead, cheeks,sub maxillary regions, chin, upper lip and nose).The depth of chemical peel is not related to the time of contact on theskin, but instead to the number of layers applied, the amount of solutionused and the application time:Mild Salipeel· Apply Salipeel with gauze soaked with a small amount of the chemicalpeel solution. Apply quickly in 10 - 15 seconds to ensure uniformapplication, to the entire treatment area without applying pressure.· Endpoint: after the formation of a white mask.· Fan the area to relieve the burning sensation, and quickly dry thesolution medium.Strong Salipeel· Apply Salipeel with gauze soaked with abundant quantities of thechemical peel solution. Apply it slowly in 15-30 seconds, while applyingsome pressure over entire treatment area.· Endpoint: formation of white mask.· Do not fan or ventilate despite the stinging sensation.Wash thoroughly with gauze soaked in water to remove the formedmask. The neutralization or rinsing of Salipeel is only an aestheticissue, therefore, if applied in a less visible area (scalp, for example),it is not necessary to perform this step.10

salipeel | product | peelingsalipeelProperties of salicylic acidSalicylic acid is known primarily for its keratolytic and comedolytic properties.The application of high concentrations produces a white mask on papules, pustulesand comedones within minutes of application. Often the cover of the pustules isbroken, permitting the acid to act from the epithelium of the follicle to the sebaceousgland.It also has anti-inflammatory (inhibits the synthesis of prostaglandin), anti itching,antiseptic, antimicrobial (reduces Propionibacterium acne), astringent, anti aging(accelerates the removal of corneocytes), photo protective (has derivatives thatabsorb RUVB) and antiepidermoplastic properties.It is a safe chemical peel that does not carry risk of burns, especially with theformulas that have a hydroalcoholic medium, because they evaporate quickly, andafter crystallization or drying occurs, there is no further penetration of activeagents.All chemical peels within this family contain salicylic acid between 25-30 % anda pH between 1.5 and 2.0.salipeelampoules (slow action)6 x 3 ml - pH 1.5+ infoFrequency or number of applicationsIn general, acne lesions respond rapidly to treatment(2-4 applications).Recommended application, every 15-30 days.COMPOSITION· 30% Salicylic acid.INDICATIONCutaneous aging, melasma, lentiges andacne scars.Gel texture.directions- Apply the gel from one ampoule overthe treatment area.- Let it act work 5-10 min.- Remove the gel with plenty of water.11

peeling | product | mandelacmandelacmandelacsolutionmandelacCmandelacLmandelacT60 ml - pH 1.560 ml - pH 1.060 ml - pH 1.060 ml - pH 0.5COMPOSITIONCOMPOSITIONCOMPOSITIONCOMPOSITION· 40% Mandelic acid.· 30% Citric acid.· 20% Mandelic acid.· 35% Mandelic acid.· 20% Lactic acid.· 20% Mandelic acid.· 5% Thioglycolic acid.· 2.5% Phytic acid.INDICATIONINDICATIONINDICATIONINDICATIONAcne and seborrheic prone skins,with folliculitis or rosacea.Skins accustomed to mandelicacid.Cutaneous aging.Skins accustomed to mandelicacid.Non uniform pigmentations andsun spots.Hemosiderotic spots(dark circles, varicose veins).directionsMandelac soluction, C and L- Hydro-alcoholic solution.- Apply by layers (1-3) with a gauze soaked in the solution.Let the application dry before applying the next layer.- Do not rinse.Mandelac T- Light texture- Apply the gel uniformly on the entire area to be treated and allowit to work for 6 – 12 minutes in facial areas, and 15 – 20 minuteson corporal areas.- Rinse with an abundance of water12

mandelac | product | peelingmandelacProperties of mandelic acidMandelac is a product line formulated with mandelic acid, recommended especiallyfor skins that have an intolerance to other alpha hydroxy acids (AHAs).Mandelic acid, also known as phenylglycollic acid, is an AHA derived from thehydrolysis of bitter almond extract.Has been commonly used to treat photo aging, irregular pigmentation, non cysticinflammatory acne and to prepare the skin in pre and post laser resurfacingtreatments.Suitable for sensitive skins, mandelic acid has a larger molecule size that makesits penetration through the stratum corneum slower, without causing irritation oritching.· Large capacity for dermal remodelingMandelic acid has a pKa of 3.41, so its ability to increase collagen synthesis, elastinand glycosaminoglycans (GAGs) in the papillary dermis is higher than other AHAssuch as glycolic acid (pKa = 3.83).mandelacexfoliating gel100 ml - pH 1.5COMPOSITION· 40% Mandelic acid.· De-pigmenting action.Melasma, hyperpigmentation, post inflammatory and lentiges improve with productsbased on mandelic acid. In many cases, melasma improves up to 50% after onemonth of treatment with a concentration of 10%.There have not been any observed any case of post inflammatory hyperpigmentationin patients with high phototypes.· Sebum regulating, antibacterial, and antimicrobial actionChemically, mandelic acid has a structure similar to other broad spectrumantibiotics. It controls and normalizes the amount of fat that penetrates into thehair follicle, reduces the presence of P. acnes, improves the appearance ofinflammatory skin pustules, comedones, papular acne, rosacea and folliculitis.In addition, preparation of the skin with mandelic acid 2-4 weeks before and afterlaser resurfacing, prevents the formation of gram (-) bacterial infections.INDICATIONChronological aging, non uniformpigmentations and spots(age, pregnancy, contraception).directions- Gel texture- Apply in an uniform mannerand let it work 3-8 minutes.- Remove with water.+ infoDifferences between gel and solutionChemical peels with gel texture exercise a longer lastingaction.The appearance of the mask and the drying of the productin chemical peels with a gel form are much slower. Becauseof this the action time on the skin increases and the acidwords on a deeper level.13

peeling | product | azelacazelacProperties ofAzelaic acidAzelaic acid is characterized byits sebum regulating, keratinnormalizing, bacteriostatic, andpigment regulating properties,as well as for inhibiting theproliferation of oxygen reactivespecies and regulatinghyperpigmentations.azelacM60 ml - pH 1.0COMPOSITION· 15% Azelaic Acid.· 18% Salicylic acid.· 10% Mandelic acid.azelacRu60 ml - pH 1.0COMPOSITION· 20% Azelaic Acid.· 10% Mandelic acid.· 5% Phytic Acid.· 5% 4N-butyl resorcinol.· 2% Ferulic acid.azelacpeel100 ml - pH 2.5COMPOSITION· 20% Azelaic acid.· 4% Lactic acid.· 2% Milk Thistle(silymarin).INDICATIONAcne, hyperpigmentations,rosacea, hyperkeratosis andphotoaging.INDICATIONAcne, hyperpigmentations,rosacea, hyperkeratosis andphotoaging.INDICATIONRosacea, acne, psoriais,folicullitis, melasma and otherhyperpigmentations.directionsazelac systemFor acne, hyperpigmentation and photoaging treatment: After cleaning, degreasing and protecting the most sensitive areas, apply two coats ofAzelac M with a gauze soaked in the solution. Start the application from the most resistant areas and move towards the most sensitive ones, waitingfor the solution to dry between each layer. Apply two layers of Azelac RU and wait for the solution to dry. If desired, you can apply focally over lesionstwo more layers of AZELAC RU. Then apply a layer of Azelac exfoliating gel and finish the treatment by sealing with Retises nanopeel 1% gel. Letit act for 8-10 hours.For the treatment of Rosacea: after cleaning, degreasing and protecting the most sensitive areas, apply two coats of Azelac M with a gauze soakedin the solution. Start the application from the most resistant areas and move to the most sensitive ones, waiting for the solution to dry betweeneach layer. Apply a thin layer of Azelac peel and let it dry. Finish by sealing the treatment with Azelac moisturizing gel. Let it act for 8-10 hours.14

argipeel - lactipeel | product | peelingargipeel · lactipeelPropierties of Arginineargipeel100 ml - pH 2.5COMPOSITION· 20% Arginine.· 20% Lactic acid.· Urea.· Aloe vera.· Alantoine.lactipeel100 ml - pH 2.5COMPOSITION· 90% Lactic acid.· 11% DMAE.Arginine is an amino acid derived from the fermentationand purification of plant carbohydrates (sugar cane). It hasa large molecule size and therefore its penetration throughthe stratum corneum is very slowly, thus avoiding anyirritation. Combined with the lactic acid, it gains all of thebenefits of alpha hydroxy acids (exfoliating properties,increases cell regeneration, improved skin firmness,diminishes hyper pigmentations...) without itching, stingingor burning.Propierties of Lactic acidLactic acid is naturally found in the skin as part of ametabolic process, its role is to help maintaining the acidmantle of the skin between a pH of 5.5 and 6.0. It has anatural moisturizing effect on the skin that draws watermolecules to the stratum corneum layer and stimulates thesynthesis of ceramides, enhancing and modulating thebarrier function.It has a clarifying effect on the color of the skin to promotea more homogeneous dispersion of melanin and exercisesan antioxidant effect and inhibit tyrosinase activity, anenzyme involved in the early stages of melanogenesis.Formulated in a gel texture which allows the acid to slowlypenetrate the skin, diminishing irritation from lactic acid.INDICATIONSensitive skin that is intolerantto other peelings.Redefines the skins surface.INDICATIONDehydrated skins, melasma andskin aging manifestations(wrinkles, loss of firmness andluminosity...).directionsargipeel- After cleansing, degreasingand protecting the mostsensitive areas, apply thechemical peel and let it workfor 5 - 10 minutes and removewith water.lactipeel- After cleaning, degreasing andprotecting the most sensitiveareas, apply the chemical peeland let it act 5-10 minutes.- After this time has expiredremove with water.15

peeling | product | pyruvic peelpyruvic peelPiruvic acidPyruvic acid produces epidermaland dermal effects. It diminishesthe cohesion of corneocytes tothe epidermis and preventsthickening of the stratumcorneum. The exfoliation occurswithout dryness, as in the skinpyruvic acid turns into lacticacid, an alpha-hydroxy acid withmoisturizing properties thatforms a protective film whichprevents skin.pyruvic peellapyruvic peelppyruvic peelplusDue to its keratolytic,sebostatic, and antimicrobialeffects it is well indicated forthe treatment of acne in all itsforms. It stimulates thesynthesis of collagen, elastinand glycol protein with an actionsuperior to glycolic acid peelingproducts, on a scale similar tothat induced by TCA, but withoutcausing discomfort and only amild erythema.60 ml - pH 1.060 ml - pH 1.0 60 ml - pH 1.0COMPOSITION· 25% Pyruvic acid.· 25% Lactic acid.COMPOSITION· 40% Pyruvic acid.· 5% Lactic acid.COMPOSITION· 50% Pyruvic acid.· 5% Lactic acid.INDICATIONSensitive and dark skins(phototypes IV to VI ).As preparatory or initiationpeeling for further treatmentwith higher concentrationspyruvic acid.INDICATIONInflammatory and noninflammatoryacne, acne scars,melasma and facial seborrhea.INDICATIONCutaneous aging (wrinkles, lossof firmness, loss of luminosity,sun spots….) stretch marks andhyperpigmentations.directionsAfter cleaning, degreasing and protecting sensitive areas, apply 2-3 layers of the chemical peel, and let it dry between layer applications.A mild skin redness indicates that it has reached the desired level of penetration.To strengthen the penetration of pyruvic acid into the skin, it is recommended to first apply a peeling layer of salicylic acid (Salipeel,Salipeel DS, Spa peel classic, or Spa peel lightening).16

spa peel | product | peelingspa peelThe formulas of the SPA peels are based on the synergy oftheir components:- Salicylic acid: potent keratolytic action. Superficial action.Enhances the penetration of other active ingredients.- Pyruvic acid: Dermaplastic action. Epidermal action tostimulate the deep papillary dermis.- Retinoic acid: Orthodromic action (Keeps the skin in normalphysiological conditions) and sebum regulation.spa peelclassic60 ml - pH 1.0COMPOSITION· 15% Salicylic acid· 8% Pyruvic acid· 5% Lactic acid· 0.1% Retinoic acidspa peellightening60 ml - pH 1.0COMPOSITION· 15% Salicylic acid.· 8% Pyruvic acid.· 5% Lactic acid.· 0.1% Retinoic acid.· 2% Undecylenoylphenylalanine.· Diacetyl boldine.INDICATIONPhotoaging, expression lines.Actinic roughness, acne,seborrhea, scars, comedonegenicand papulopustular acne.INDICATIONHyperpigmentations, melasma(chloasma), melanotic pigmentationsinduced by perfumes andmedicines.Photo aging spots.directions- After cleaning, degreasing and protecting sensitive areas, apply2-3 layers of the chemical peel, and let it dry between layerapplications.- After drying, each layer displays a white mask in the treatedarea by the crystallization of salicylic acid in the skin. Washingis optional: after the applied chemical peel (aesthetic purposes).17

peeling | product | nomelan fenolnomelan fenolnomelan fenollightnomelan fenolmediumnomelan fenolforte60 ml - pH 0.5 60 ml - pH 0.5 20 ml - pH 0.5nomelan fenolkh60 ml - pH 0.5COMPOSITIONCOMPOSITIONCOMPOSITIONCOMPOSITION· Phenol· Trichloroacetic acid· Glycolic acid· Salicylic acid· Ascorbic acid· Mandelic acid· Phytic acid· Retinoic acid· Ferulic acid· Phenol· Trichloroacetic acid· Glycolic acid· Salicylic acid· Ascorbic acid· Mandelic acid· Phytic acid· Retinoic acid· Ferulic acid· Trichloroacetic acid· Glycolic acid· Salicylic acid· Ascorbic acid· Mandelic acid· Phytic acid· Retinoic acid· Ferulic acid· Phenol· Trichloroacetic acid· Hydroquinone· Kojic acid· Alpha - arbutin· Glycolic acid· Salicylic acid· Ascorbic acid· Mandelic acid· Phytic acid· Retinoic acid· Ferulic acidINDICATIONINDICATIONINDICATIONINDICATIONSuperficial wrinkles and acne.High phototypes.Wrinkles, dermal melasma andacne scars.Focal applications, deepwrinkles, stretch marks andflaccidity.Dermal melasma. Patientstolerant to hydroquinone.Depigmenting.directions1. Clean and degrease the area to be treated, and protect delicate areas withSilkses skin moisturizing protector.2. Apply Nomelan fenol light, Medium, FD, or KH on the area to be treated bytapping with gauze which has been saturated with the solution. Apply in arapid and uniform manner, without rubbing.- Extend towards the ear lobes and the forehead, 2 mm behind the hairline.- The applied layer should be left to dry (2-3 minutes approx.) before applyingthe next one.- If necessary, apply Nomelan fenol forte directly on lesions to be treated(smoking lines (barcode), deep wrinkles, lentigos) using a gauze or a cottonswab saturated with the solution.3. The number of applied layers depends on the type and thickness of the skinand of the planned end-point. The higher the number of layers applied, thedeeper the effect.- For lighter skins (phototype I-III) it is advisable to apply 2-4.- For darker skins (phototype IV-VI) do not apply more than 2 layers on thefirst session.4. This type of solutions does not need rinsing, instead it needs to be sealed.In order to seal, apply a thin layer of Retises Forte and let it act for around10 hours.5. Provide the patient with a Nomelan phenol home treatment kit.18

nomelan fenol | product | peelingnomelan fenolProduct line intended to maintain the thickness of the stratum corneum anddermoepidermal cell renewal.Solutions for chemical peels containing phenol, Trichloroacetic acid, retinoic acid,and a mixture of hydroxy acids (glycolic, ascorbic, salicylic, and mandelic), alongwith phytic acid.Properties- Unbuffered hydroalcoholic solution: pH 0.5 - 1.0- Painless: no need of analgesics during the application- The depth of the solution depends on the number of applied layers- Maximum application of 5 ml of product per session- Results in 7 days: renewed and bright complexion;homogeneous skin color and texture- Induces neither hyper- nor hypopigmentation- Number of treatments: 3 or 4 chemical peels every 21-30 days.ACTIVE INGREDIENTS ACTION EFFECTnomelan fenolfd60 ml - pH 0.5COMPOSITION· Phenol· Trichloroacetic acid· Kojic acid· Diacetyl Boldine· Undecylenoyl Phenylalanine· Glycolic acid· Salicylic acid· Ascorbic acid· Mandelic acid· Phytic acid· Retinoic acid· Hydroalcoholic baseINDICATION1 st GROUPCHEMICALAGENTS2 nd GROUP2 rd GROUPTCAPHENOLRETINOICAHAsSALICYLICPHYTICDEPIGMENTINGAGENTSProteins coagulationEpidermis destruction.1. Strong keratolitic effectProteins coagulation: destroyssulphide.2. Anesthetic effect on the nerveendings of the superior dermis.3. Antiseptic action.1. Normalizes the keratinization.2. Stimulates the collagen synthesis+ antiglycation activity +reparation action.3. Normalizes the melanocyte´sactivity.Moisturizing, keratoplastic,keratolitic and sebum regulatingproperties.Keratolitic and comedolytic action.Whitening agent Block the ironand the copper Avoids thefomation of EROs.KH Kojic + Hydroquinone + Alpha+ Arbutin.FD Undecylenoyl Phenylalanine+ Diacetyl boldine + KojicNew tissue firmer andmore elastic skin.1. Epidermal removal athinner, smoother and morehomogenic skin.2. Numbness feeling of theupper lip during theapplication.3. Improve the acne proneskins.1. Improves appearance andthe quality of the skin.2. Reduces the deepnessof the wrinkles.3. Clarifies spots.Firmer, more resistant andhydrated skin.Comedones obstruction.Smoother, thinn er skinwithout excess oil.Clarifies the spots andprevents the oxidativestress.Inhibits the melanogenesisin several ways.Dermal melasma. Patientssensitive to hydroquinone.Depigmenting.4 th GROUPEXCIPIENTSAdjuvants components (PPG, AH,H2O) Hydroalcoholic base.Limits the absorption ofpeeling.Pack Nomelan FenolNomelan Fenol (Light + Medium + Forte)Post-treatment Kit· Hidraven soap free foamy cream· Nomelan C post treatment cream· Silkses cutaneous moisturizingprotector· Retises Ct Yellow peel.19

peeling | product | nomelan cafeiconomelan cafeiconomelan cafeicostep 0nomelan cafeicolightnomelan cafeicoforte60 ml - pH 2.5 60 ml - pH 1.0 60 ml - pH 1.0COMPOSITION· 14% Resorcinol.· 14% Salicylic acid.· 10% Lactic acid.· 2% Citric acid.· Trichloroacetic acid· Caffeic acid· Glycolic acid· Salicylic acid· Phytic acid· Mandelic acid· Ferulic acid· Ascorbic acid· Retinoic acidCOMPOSITION· Trichloroacetic acid· Caffeic acid· Salicylic acid· Phytic acid· Mandelic acid· Ferulic acid· Ascorbic acid· Retinoic acidCOMPOSITIONINDICATIONPreparatory chemical peel to be combinedwith other Nomelan Caffeic peelings.INDICATIONSuperficial wrinkles, superficial melasmaand acne scars.INDICATIONMedium deep wrinkles, scars and stretchmarks.directions1. Clean and degrease the area to be treated, and protect delicate areaswith Silkses skin moisturizing protector.2. Apply one layer of Nomelan cafeico step 0 by tapping with a gauzesaturated with the solution. Apply in a rapid and uniform manner, avoidrubbing, and let it dry.3. Apply Nomelan cafeico light, forte or depigmenting in layers and ina uniform and rapid manner without rubbing.- If necessary, apply Nomelan cafeico forte focally over lesions to betreated.The number of applied layers will depend on the type and thickness ofthe skin and of the planned end-point. The higher the number of layers,the deeper the effect.· For lighter skins (phototypes I-III) it is advisable to apply 2-4 layers.· For darker skins (phototypes IV-VI) do not apply more than 2 layers.4. Seal the treatment with Retises forte and allow it to act for 8-10 hours.5. Provide the patient with the Nomelan home treatment kit20

nomelan cafeico | product | peelingnomelan cafeicoProduct line intended to maintain the thickness of the stratum corneum and fordermoepidermal cell renewal.Nomelan cafeico product line has presented us as an alternative to phenol chemical peels (Nomelan Phenol).· Caffeic acid is a derivative of phenol with antioxidant properties, protecting thecellular DNA and exerting a chemopreventive action. Inhibits tyrosinase, an enzymeinvolved on the melanogenesis process. Modulates immune disorders and is apotent antifungal agent.Properties:- Hydroalcoholic solutions: pH 1.0 - 2.5- Quick and easy treatment application: 15 minutes.- During the application it is normal for the patient to feel an itching orburning sensation.- The depth of the peel depends on the number of coats applied, the presentationused and the seal with retinol.nomelan cafeicobleaching60 ml - pH 1.0· Trichloroacetic acid· Caffeic acid· Undecylenoyl Phenylalanine· Kojic acid· Glycolic acid· Salicylic acid· Phytic acid· Mandelic acid· Ferulic acid· Retinoic acidDermal melasma.COMPOSITIONINDICATIONPost-treatment Kit· Hidraven soap free foamy cream· Nomelan C post treatment cream· Silkses cutaneous moisturizing protector· Retises Ct Yellow peel.21

peeling | product | retisesretisesretisesforte15 ml - pH 3.8COMPOSITION· 10% Retinol.· 1% Retinyl Propionate.retisesspot peel15 ml - pH 3.5· 10% Citric acid.· 5% Retinol.· 5% Emblica.COMPOSITIONretisesCT6 x 2 ml - ampoules6 x 5 ml - sachetsCOMPOSITIONAmpollas:· 10% Ascorbic Glucoside.· 5% Niacinamide.Sobres:· 4% Retinol.· 1% Retinyl Propionate.INDICATIONTreatment of skin aging manifestations,hyperpigmentations and distension stretchmarks.INDICATIONHyperpigmentations (melasma, lentiges…)and photoaging.INDICATIONTreatment of skin aging manifestations,hyperpigmentations and distension stretchmarks.directionsretises forteApply over the area to be treated or focallyover lesions.Let it act for approximately 8 hours.Remove with water.retises spot peelApply to the treatment area or specificlesion. Let it work for about 8 hours.Wash the treated area.retises CT yellow peelApply 1 / 2 or 1 ampoule of Vitamin C andwait a few minutes. Apply a thin layer ofthe retinol cream on the area being treated.Let it work for about 8 hours.Wash the treated area.22

etises | product | peelingretisesRetinol propertiesRetinol is a retinoid precursor of retinoic acid. It accelerates mitosis, increasesenzyme activity and normalizes keratinization. It nourishes the skin, prevents theappearance of wrinkles, reduces the depth of existing wrinkles and improves skinelasticity. Moreover, retinol attenuates stains caused by excessive exposure toUV rays, regulating the proliferation and mobility of melanocytes.The chemical peel can be combined with other anti aging, repairing ordepigmentation treatments. (Chemical peels, laser, IPL ...).retises1 %30 ml - pH 6.5COMPOSITION· 3% Biopeptide CL.· 1% Retinol.· 1% Ascorbyl glucoside.INDICATIONNutritive and restorative cream indicatedfor aging and / or photo damaged skins,acne scars and sretch marks.+ inforetises 1% is a medical prescription homeuse cream.directionsApply 3 times a week at night with agentle massage.23

peeling | product | tcaTCATCA15%TCA25%TCA35%60 ml - pH 1.0 60 ml - pH 0.7 60 ml - pH 0.5TCAcross60 ml - pH 1.0COMPOSITIONCOMPOSITIONCOMPOSITIONCOMPOSITION· 15% Trichloroacetic acid.· 25% Trichloroacetic acid. · 35% Trichloroacetic acid.· 50% Trichloroacetic acid.INDICATIONINDICATIONINDICATIONINDICATIONPhotoaging and melasma.Photoaging and melasma.Photoaging and melasma.Acne scars, deep wrinkles,xanthelasma and syringoma.directionsTCA 15 · 25 · 35 %Apply over the treatment area with a cotton swab or gauze, quicklyand uniformly. The solution is applied in layers. The contact timeof this solution depends on the time it takes each layer to dry.TCA crossApply to lesions with a Q-tip or gauze, quickly and uniformly. Thesolution is applied in layers. The contact time of this solutiondepends on the time it takes each layer to dry.24

glycolic acid | product | peelingglycolic acidTCATrichloroacetic acid removesskin layers which are aged,damaged or degraded anytype of organic or externalprocesses. Producescoagulation in cutaneousproteins resulting in thedestruction of the epidermallayer, which will be replacedby a new epidermis and newconnective tissue.Glycolic acidglycolic acid25%glycolic acid50%glycolic acid70%The result of this chemicalpeel can be summarized intwo steps:- Exfoliation: eliminatesdeath cells and stimulatescellular renewal.- Epidermolisis: destroysepidermal cells.60 ml - pH 1.2060 ml - pH 0.760 ml - pH 0.5COMPOSITIONCOMPOSITIONCOMPOSITION· 25% Glycolic acid.· 50% Glycolic acid. · 70% Glycolic acid.INDICATIONPhotoaging.Melasma and sun spots.Acne.INDICATIONPhotoaging.Melasma and sun spots.Acne.INDICATIONPhotoaging.Melasma and sun spots.Acne.directionsAplicar sobre la zona a tratar con una torunda de algodón o una gasa, de forma rápida y uniforme.La solución se aplica por capas. El tiempo de contacto de la solución con la piel vendrá marcado porel tiempo que tarde en secarse cada capa.25

peeling | product | masksmasksMask product line providing excellent skin hydration increasing its elasticity and permeability.Incorporates select active ingredients for specific treatments of different skin types andconditions, providing benefits against different pathologies.The masks work by optimizing active ingredient penetration thanks to their direct contact withthe skin, through occlusive therapy. Because of this they are able to pass a multitude of activeingredients into the dermis allowing them to work from the inside - out.PROPIMASKPropimask is a facial mask line with a non braided polypropylene matrix, impregnated withactive ingredients.Polypropylene is a linear hydrocarbon that has several groups present - CH3 grants greaterhardening and stabilization in respect to oxidation.Material of SYNTHETIC origin. Provides suitable and sufficient adhesion to the skin, allowingocclusion of the ingredients. Medical use only.Types of masks:Kojic acid, Salicylic acid, AHA´s, Aloe Vera, BTses, Chitosan, Collagen booster, Daeses, Endorphins,Vitamin C, Youth booster, and Healing.directions1.- Clean and degreasethe skin.2.- Apply the mask,molding and fitting itto the face.3.- Wait for 20-30minutes.4.- Carefully remove themask and massagethe skin.26

propimask | product | peelingpropimaskpropimaskkojic acidpropimaskAHA’spropimaskaloe vera1 unit1 unit 1 unitCOMPOSITION· 5% Glycerine.· 3% kojic acid.· Depigmenting herbal compex.· Vitamins A and E.INDICATIONSkins with hyperpigmentations andphotoaging.· 5% Lactic acid.· 5% Citric acid.· 3.5% Glycolic acid.Photoaged skins.COMPOSITIONINDICATION· 10% Aloe vera.· 2.5% Glycerine.· Chitosan.Irritated skins.COMPOSITIONINDICATIONPROPERTIES· Kojic acid, and the herbal complex, inhibitmelanogenesis and block solar radiation.Smoothes the skin without producingirritation or photo-sensibility.· Vitamin A (retinyl acetate) acts as aprotecting agent, normalizes dryness andkeratinization of the skin, revitalizes skintissue and improves the production ofcollagen. Has antioxidant properties.· Glycerine has a moisturizing actionreinforcing the skins own moisture control.· Vitamin E (tocopherol acetate) helps tocombat premature aging caused by freeradicals and ultraviolet rays. Increasesmicrocirculation, improves skin elasticityand reduces wrinkles.PROPERTIES· Alpha hydroxy acids have a natural origin.They are used to renovate the skin andeliminate wrinkles. They work by removingdead cells from the stratum corneum, inthis way eliminating the most superficialwrinkles and accelerating the appearanceof new tissues, giving a smoother, brighterand more elastic skin tone.PROPERTIES· Aloe vera penetrates and deeplymoisturizes all layers of the skin, reestablishinga hydro-lipid equilibrium(moisturizing action). Additionally itstimulates the regeneration of the tissuesand accelerates cellular turnover(resurfacing action), stops microbial growth(bacteriostatic action), reduces swelling(calming action), eases itching anddecreases pain (anesthetic action).· Glycerine has a moisturizing actionreinforcing the skins own moisture control.· Chitosan characterized by its moisturizing,bacteriostatic and fungistatic properties.27

peeling | product | propimaskpropimaskpropimaskbtpropimaskchitosanpropimaskdaeses1 unit1 unit 1 unitCOMPOSITION· 5% Argireline ®(acetyl hexapeptide-3).· 5% Matrixyl ®(palmitoyl pentapeptide-3) .INDICATIONYoung skins with expression lines.· 5% Glycerine.· Chitosan.COMPOSITIONINDICATIONDehydrated and irritated skins.COMPOSITION· 6% DMAE.· 4.5% Lactic acid.· 3% Glycolic acid.INDICATIONFlaccid or aged skins.PROPERTIES· Argireline (acetyl hexapeptide-3) reducesthe depth of facial wrinkles produced bythe muscle contractions of facialexpression, especially on forehead and inthe eye contour.· Matrixyl (palmitoyl pentapeptide-3)stimulates fibroblasts so they synthesizeconnective tissue molecules, especiallycollagen and glycosaminoglycans.PROPERTIES· Glycerin replaces moisturizing agents lostby the skin and returns water to theepidermis. Also performs a moisturizingaction resulting in the reinforcement of theskins own moisture control.· Chitosan characterized by its moisturizing,bacteriostatic and fungistatic properties.PROPERTIES· DMAE improves the firmness of the skinsurface (firming action), stimulates muscleactivity producing stretching with a liftingeffect (tightening effect), increaseselasticity, reduces wrinkles and stabilizescell membranes, repairs damage tocollagen caused by free radicals(antioxidant action).· Alpha hydroxy acids accelerate cellularrenewal and stimulate the synthesis ofcollagen and elastin.28

propimask | product | peelingpropimaskpropimaskendorphinspropimaskcollagen boosterpropimasksalicylic acid1 unit1 unit 1 unitCOMPOSITIONAcetyl dipeptide-1 cetyl esterINDICATIONIrritated and sensitive skin.COMPOSITION· 8% Matrixyl.(Palmitoyl Pentapeptide-3)· 2% Ginkgo Biloba· Centella Asiatica.INDICATIONPrevention of premature aging.· Salicylic acid.· Herbal complex.· Vitamins A and E.· Collagen.COMPOSITIONINDICATIONOily and acne-prone skins.PROPERTIESAcetyl dipeptide-1 cetyl ester stimulatesthe synthesis of endorphins, providingrelief and well-being to the skin.PROPERTIES· Matrixyl ( PAL-KTTKS ) is a mimetic thatstimulates fibroblasts in order tosynthesize connective tissue molecules,especially collagen I, III, IV, fibronectin andglycosaminoglycans. In this way, itregenerates the dermal matrix, reducesspots caused by skin aging, improves skinfirmness and reduces wrinkles.· Gingko biloba captures free radicals inthe skin, and as a result, protects the skinfrom premature aging.· Centella asiatica strengthens thestimulating effect of collagen and GAGs ofthe PAL-KTTKS.PROPERTIES· Salicylic acid is ideal for the treatment ofacne prone and oily skin due to itsbacteriostatic, sebum-regulating andkeratolitic properties.· Vitamin A (retinyl acetate) acts as aprotecting agent, normalizes dryness andkeratinization of the skin, revitalizes skintissue and improves the production ofcollagen.· Vitamin E (tocopherol acetate) helps tocombat premature aging caused by freeradicals and ultraviolet rays. Increasesmicrocirculation, improves skin nutrition,improving elasticity and reducing wrinkles.Also has anti-inflammatory properties thathelps the natural regeneration process ofthe skin.· Collagen improves skin hydration thanksto its water retention ability. Also, itincreases the elasticity of the skin anddelays skin aging.29

peeling | product | propimaskpropimaskpropimaskvitamin cpropimaskyouth boosterpropimaskhealing1 unit1 unit 1 unitCOMPOSITION· 2% Encapsulated vitamin C.· 2% Sorbitol.· 2% Glycerine.· 5% Glycerine.· Chitosan.· Soy isoflavones.COMPOSITIONCOMPOSITION· 5% Panhtenol.· 2.5% Calming complex.· 0.1% Bisabolol.Photoaged skin.Dehydrated skin.Dull skin.INDICATIONPROPERTIES· Vitamin C protects the skin from radiationand oxidative damage. Stimulates thesynthesis of collagen and elastin.Moisturizes the skin promoting theformation of the lipid barrier in the statumcorneum. Helps to rebuild and hydrate theepidermis. Favours melanogenesis andhelps with epithelization.· Glycerin and sorbitol replace moisturizingagents lost by the skin and returns water tothe epidermis. Performs a moisturizingeffect on the skin and as a result, strengthensthe skins own moisture control.INDICATIONDry and aged skins.Flaccid and photo-aging skin.PROPERTIES· Glycerin replaces moisturizing agents lostby the skin and returns water to theepidermis. Performs a moisturizing effecton the skin and as a result, strengthens theskins own moisture control· Soy isoflavones possess importantantioxidant properties which protect the skinfrom the harmful effects of free radicals(main cause of photo-aging). Stimulatescellular renewal and reduces the degradationof supporting tissue. Improves elasticity andhydration, reducing dermal wrinkles.· Palmitoyl tetrapeptide normalizesdryness and keratinization, revitalizes skintissue and improves the production ofcollagen.INDICATIONDamaged and cracked skin.PROPERTIES· Panthenol stimulates resurfacing and scarrepair on the skin. Prevents skindeterioration and prolongs the hydration ofthe cutis.· Calming complex and bisabolol reduceinflammation, posses emollient propertiesthat alleviate and sooth irritates skin.30

additives | product | peelingadditivesadditiveglowing50 g.additiveantioxidant50 g.additiveresveraderm50 g.COMPOSITION· Ascorbic acid.· Active ingredient enhancer.INDICATIONDull and or photoaged skins.COMPOSITION· Ascorbic acid.· Thioctic acid.· Grape polyphenols.· Soy isoflavones.INDICATIONMature and aged skins.· Resveratrol.· Ascorbic acid.· Tioctic acid.· Citric acid.COMPOSITIONINDICATIONMature, flaccid and photo-aged skins.PROPERTIESAscorbic acid (vitamin C) preventsoxidative damage and is involved in thesynthesis of collagen, improving skinhydration and smoothness, prevents theformation of free radicals and reduceswrinkles. Photo protective action. Clarifiesthe skin by inhibiting the synthesis ofmelanin in melanocytes. Also contains aningredient that facilitates the penetrationof various active ingredients in the skin.PROPERTIES· Thioctic acid is a natural nutrient consideredto be a "universal antioxidant." Reducesconcentrations of free metals (iron)responsible for the formation of new freeradicals.· Soy isoflavones, as well as polyphenols, haveantioxidant properties that protect the skinfrom the harmful effects of free radicals. Inaddition they stimulate cellular renewal andreduce the degradation of supporting tissue,improving skin elasticity and hydration, whilereducing wrinkles and flaccidity.PROPERTIES· Resveratrol comes from the polyphenolsfamily with important biological effects onhealth and skin, prevents accelerated agingprocess and protects Cellular DNA. Stimulatesand increases the formation of our bodies ownantioxidant defences by preventing freeradical attacks, thus prolonging cellular life.· Ascorbic acid prevents oxidative damage,stimulates collagen synthesis, homogenizesthe skin colour and smoothness out the skin.· Tioctic acid reduces the concentration of freemetals responsible for the formation of newfree radicals.Citric acid stimulates collagen synthesis andprevents oxidative damage.31

peeling | product | additivesadditivesadditivebleaching mix50 g.additivebleaching k50 g.additiveanti-acne50 g.· Kojic acid.· Emblica extract.· Green tea.· Enhancer complex.COMPOSITIONINDICATIONHyperpigmented skins.Sensitive skins.COMPOSITION· Kojic acid.· Active ingredient enhancer.INDICATIONHyperpigmented skins.Resistant skins.COMPOSITION· Nicotinamide.· Salicylic acid.· Aloe vera extract.· Active ingredient enhancer.INDICATIONOily and acne prone skins.PROPERTIES· Kojic acid inhibits melanogenesis and blockssolar radiation.· Emblica is a potent depigmenting andantioxidant agent.· Turmeric inhibits tyrosinase activity,preventing the formation of melanin.· Green tea is rich in flavonoids, catechins,vitamins and beta-carotene, it is one of therichest sources of antioxidants that stop cellaging caused by free radicals. Reaffirms tissue,provides greater turgidity and improves skinquality.PROPERTIES· Kojic acid inhibits melanogenesis andblocks solar radiation.It also has an ingredient that facilitates thepenetration of various active ingredientsin the skin.PROPERTIES· Nicotinamide (vitamin B3, niacin) has antiinflammatoryproperties, which inhibits thechemotaxis of neutrophils, stops lymphocytetransformation, and prevents the degradationof mast cells.· Salicylic acid is an excellent sebum regulatorthat possesses bacteriostatic properties andaccelerates epidermalturnover remodelling the skin.· Aloe vera is a natural calmer. Possesseshealing, skin tissue regeneration, bactericidal,and emollient properties. Protects the skinfrom the harmful effects of free radicals.· Active ingredient enhancer facilitatespenetration of active ingredients into the skin.32

additives | product | peelingadditivesadditivecollagen booster I50 ml - pH 3.2 50 ml - pH 4.8additivecollagen booster IIadditivecollagen booster III12 x 4 mlCOMPOSITION· 15.4% Matrixyl.· 2% Centella Asiatica Extract.COMPOSITION· 100% Matrixyl.(Palmitoyl Pentapeptide-3).· 4% Retinol.COMPOSITIONPhotoaged skins.INDICATIONAging skins.INDICATIONINDICATIONAging and/or hyperpigmented skins.PROPERTIESAscorbyl glucoside has greater stabilitythan conventional vitamin C. Possessesregenerating properties (ascorbylglucoside and centella asiatica). Inhibitsthe synthesis of melanin and reducesexisting melanin, preventing and reducingcutaneous pigmentations. Also catchesfree radicals, preventing cutaneous photoaging.PROPERTIESPalmitoil pentapeptide (Matrixyl)stimulates fibroblasts causing them tosynthesize connective tissue moleculesspecifically collagen, fibronectin andglycosaminoglycans. In this way the dermalmatrix is regenerated, improving thefirmness of the skin and reducing wrinkles.PROPERTIESRetinol (vitamin A) is a skin protector.Normalizes dry skin, as it retains waterkeeping the skin hydrated and more elastic.Moreover, it tends to restore the normalmitosis rhythm and moderately enhancessome enzymatic reactions, compensating fordisturbances and deficiencies in aging skin.33

peeling | product | additivesadditivesAdditives are products made to be combined with chemical peelings, in order tosupport the treatments principal active ingredients, improving the result of thepeeling.directionsPowder additives are mixed with a gel peelingat the time of application. 1/4 ladle of theadditive, + 1/2 ladle of the peeling.Gel or cream additives are applied after rinsingthe peel and are not removed afterwards.additivelifting effect100 ml - pH 5.5· 15% lactic acid.· 10% DMAE.Wheat proteins.COMPOSITIONINDICATIONFlaccid and/or aged skins.PROPERTIES· Lactic acid has hydrating, and regeneratingproperties. It has the capacity to lock waterin the stratum corneum layer of theepidermis, bringing more flexibility to theskin.· DMAE improves the superficial firmnessof the skin (firming action) stimulatesmuscular activity, producing a stretchinglifting effect. (tensing effect), increasesskin elasticity, and reduces wrinkles.· Wheat proteins induce an immediatetensing effect, and reduce skin roughness.34

ampoules | product | peelingtreatment ampoulesglowingampoulesreaffirmingampoulesanti-wrinkleampoules5 x 2 ml5 x 2 ml 5 x 2 mlCOMPOSITION· 12% Ascorbic acid.COMPOSITION· 8% DMAE.· 7% Lactic acid.COMPOSITION· 15% Argireline ®(Acetyl hexapeptide-3).INDICATIONDull and/or dehydrated skin.INDICATIONAged and flaccid skin.INDICATIONSkin with expression lines.PROPERTIESRevitalizing serum formulated with pureVitamin C.Allows for the quick recovery of luminosity,hydration, smoothness and firmness lostover time from years of solar exposure.PROPERTIESFirming serum with immediate liftingeffects, smoothes out wrinkles andincreases the elasticity of the skin.· DMAE stimulates the synthesis ofacetylcholine (neurotransmitter) toincrease muscle contraction, obtaining animmediate tightening effect.· Lactic acid has moisturizing and tighteningproperties and promotes cell regeneration.PROPERTIESSerum that smoothes wrinkles andexpression lines caused by continuousfacial movements by inhibiting thesynthesis of acetylcholine.· Argireline® acts at the same level as BTX,reducing the depth of wrinkles caused bycontractions from expressions andprevents skin aging caused by continuousfacial movements.35

peeling | product | ampoulestreatment ampoulesanti-couperosisampoules5 x 2 mlbleachingampoules5 x 2 mlpurifyingampoules5 x 2 mlHydrating Serum that inhibits signs ofredness. Exerts a calming effect thatreduces swelling and erythema fromrosacea or couperosis.· Azeloglicina® exercises anti-inflammatoryand antiradical effects, fighting rednessand papulopustules. Inhibits 5-alphareductase, thereby decreasing sebumsecretion. Has an antibacterial action andinhibits tyrosine, homogenizing the skincolor. Controls the hyperkeratosis due toits cytostatic anti proliferative effects.· Niacinamide reduces facial erythema andpossesses a potent anti-inflammatoryaction.COMPOSITION· 5% Azeloglicina®.· 1% Niacinamide.Liquorice Extract.INDICATIONTreatment of red and sensitive skins.PROPERTIES· Licorice extract is a depigmentationagent that inhibits tyrosinase andsubsequent oxidative enzyme systems.COMPOSITION· 5% Alpha-arbutin.· 3% Ascorbyl glucoside.Liquorice Extract.INDICATIONPrevention and treatment of hyperpigmentations.PROPERTIESBleashing serum that attenuates spotsand homogenizes the skin tone.· Alpha-arbutine lightens skin spots andmarks by blocking tyrosinase andincreasing the degranulation of mast cells,disrupting the formation of new pigment.· Ascorbyl glucoside has regenerativeproperties, inhibits melanin synthesis andreduces existing melanin. Furthermore, ittraps free radicals, preventing skinphotoaging.· Liquorice extract is a potentdepigmentation agent that inhibits theformation of reactive oxygen species inskin (02) and tyrosinase.· 5% Azeloglicina ®.· 5% Sebum-regulating Complex.· Salicylic acid.· Niacinamide.Acne prone skins.Keratolytic and comedolytic serum that,regulates sebaceous secretion and reducesskin redness.· Azeloglicina® exercises anti-inflammatoryand antiradical effects, fighting rednessand papulopustules. Inhibits 5-alphareductase, thereby decreasing sebumsecretion. Has an antibacterial action whichis very useful with acne cases.· Sebum regulating complex inhibits theaction of 5- alpha- reductase diminishingandrogenic activity. Has astringent andanti-inflammatory actions.· Salicylic has bacteriostatic, sebumregulating, and keratolytic properties.· Niacinamide reduces facial erythema andpossesses a potent anti-inflammatoryaction.COMPOSITIONINDICATIONPROPERTIES36

pre-peeling solutions | product | peelingsolutionsdegreasingsolutionsensyseslotionneutralizinglotion200 ml - pH 5.0200 ml - pH 5.5 200 ml - pH 8.5COMPOSITION· Glycolic-glycolate.· Hamamelis virginiana (Witch-Hazel).INDICATIONPrepares the skin for superficial chemicalpeel applications.COMPOSITION· 6% Strontium Chloride.· 6.7% Calming complex.· 5% Niacinamide .INDICATIONSoothing lotion indicated for sensitive skin.Prepares and protects the skin before theapplication of peelings. Calms skin exposedto irritating treatments.COMPOSITION· 9.5% Sodium Bicarbonate.· 1% Camomile.INDICATIONNeutralizes cosmetic treatment productswith alpha and beta hydroxy acids.PROPERTIESRemoves makeup residues that remainafter the application of cleansing lotions.Degreases skin that will be subjected tochemical peels, favouring the penetrationof other agents.· Strontium chloride inhibits a burningsensation, irritation and itching, propertiesof AHA's. Inhibits erythema and reducesepidermolysis.· Niacinamide increases the barrier effectof the skin, protecting it from environmentalfactors. Reduces facial erythemaand possesses a strong anti-inflammatoryaction.PROPERTIES· The calming complex is made up of activeingredients with moisturizing, antiinflammatoryand soothing properties.PROPERTIESLotion with a basic pH that counteracts theaction of chemical peels (acidic pH).37

peeling | product | therapeutic and complementarytherapeutic and complementary productsabradermolmicrodermabrasion cream200 grCOMPOSITION· 42% Aluminium oxide crystals.· 3% Shea butter.· 5% Nicotinamide.INDICATIONNon inflammatory acne.Dilated pores.Scars (acne, atrophic).Stretch marks.Hyper pigmentations.Wrinklesmandelacscrub100 mlCOMPOSITION· 8% Polyethylene granules.· 5% Aloe barbadensis.· 2% Mandelic acid.· Camomile.· Clorhexidine digluconate.INDICATIONCleansing and hygiene of mixed, oily, andacne-prone skins.rosoilampoules6 x 3 ml· 95% Rose hip oil.· Vitamin E acetate.Scars.Stretch marks.Damaged skins.Aging.COMPOSITIONINDICATIONPROPERTIES· Aluminium oxide crystals produce a softmechanical abrasion on the upper layersof the epidermis, eliminating dead cellsand promoting skins natural repairmechanisms. Resulting in an increase insmoothness and luminosity and animprovement in skin texture.· Niacinamide Reduces facial erythema andpossesses a potent anti-inflammatoryaction.· Shea butter possesses a high content ofunsaturated fatty acids (linoleic, oleic,palmitic and stearic acids) which haveexcellent skin compatibility. Protects theskin from external aggressions andfavours skin regeneration. Additionally itpossesses smoothing, hydrating, emollientand anti-irritating properties.PROPERTIES· Polyethylene microgranules eliminatedead cells, unclog pores, and leave the skinimpurity free.· Mandelic acid gives the same sebumsecretion control properties combined inglycolic and salicylic acid, but with lessirritation.· Aloe and chamomile reduce the irritantcomponent associated with oily and acneprone skins.PROPERTIESContains high levels of polyunsaturatedessential fatty acids (39% linoleic and 41%linolenic) that are responsible for the skinsregenerative actions.Contains natural tretinoin, a derivate ofvitamin A that delays aging effects.Increases collagen and elastin levels,resulting in firmer and softer skin.38

therapeutic and complementary | product | peelingtherapeutic and complementary productsrosoilregenerating maskhidraloealoe geldaeseslifting and firming cream100 ml - pH 6.5250 ml - pH 6.0 100 ml - pH 5.0COMPOSITION· 5% Rose hip oil.· 1% Meadow foam seed oil.· Onagra oil (Evening primrose oil).COMPOSITION· 100% Aloe barbadensis.· 2% Plant extracs.· 1.5% Rose hip oil.· Glycyrrhetinic acid.· Triclosan.· Bisabolol.· Allantoin.COMPOSITION· 6% DMAE.· 5.7% Glycolic acid.INDICATIONSkin irritations after chemical treatments.Cutaneous aging.INDICATIONIrritated skin.Burns, wounds and ulcers.Itching and stinging.INDICATIONFlaccid skins (face and body).Aging.PROPERTIESPink clay mask containing active ingredientswith hydrating, soothing, calming andrepairing properties.Ideal after aggressive treatments (chemicalpeels or microdermoabrasions) since itprovides high levels of EFAs to the skin, thevital constituents of cell membranes,responsible for skin regeneration.Light gel that is quickly absorbed.Anti-inflammatory and anti-irritant thanks toits content of mallow, chamomile, calendula,hamamelis, horse chestnut, tilia and birch.Has antibacterial (aloe and triclosan),moisturizing, soothing, and refreshingproperties.Stimulates and boosts cutaneousregeneration (aloe, allantoin and rose hipoil).PROPERTIESPROPERTIES· DMAE, improves the firmness of the face,neck, jawline area (firming action).Stimulates muscle activity producing astretching and lifting effect (tensingeffect), increases skin elasticity, reduceswrinkles and stabilizes cell membranes torepair damage in collagen caused by freeradicals.· Glycolic acid reduces coenocyte cohesionfacilitating the penetration of other activeingredients and increasing deposits of newcollagen and GAG's.39

peeling | product | therapeutic and complementarytherapeutic and complementary productsbtsesmoisturizing cream100 ml - pH 6.0COMPOSITION• Relaxing peptides:· Hydrolized hibiscus esculentus extract(Myoxinol®).· Acetyl glutamyl heptapeptide-1(SNAP-8®).· Palmitoyl tripeptide-5 (Syn Coll®).· Rosa mosqueta.btsesserum forte30 ml - pH 6.5COMPOSITION• Relaxing peptides:· Hydrolized hibiscus esculentus extract(Myoxinol®).· Acetyl glutamyl heptapeptide-1(SNAP-8®).· Acetilhexapéptido 25 (Inyline®).· Palmitoyl tripeptide-5 (Syn Coll®).· Retinol.nomelanC30 ml - pH 6.0COMPOSITION· Silanol.· Panthenol.· Essential fatty acids.· Rose hip oil.· Bisabolol.· DMS® complex.INDICATIONSkin with expression lines.INDICATIONSkin with expression lines, focal treatment.INDICATIONIrritated and damaged skins from medicaltreatments.PROPERTIES· Latest generation relaxing peptides thatwork at pre-synaptic and post-synapticlevels, reducing muscular stimulation andweakening neuromuscular transmission.Inhibit the association of contractileproteins present in muscle cells.· Palmitoyl Tripeptide-5 (SynColl)stimulates the synthesis of collagen,elastin, and GAGs, regenerating the dermalmatrix. Reduces wrinkles and improvesfirmness.· Rosehip Oil possesses skin tissueregenerating properties. Repairs,improves, and attenuates epidermalblemishes.PROPERTIES· Latest generation relaxing peptides thatwork at pre-synaptic and post-synapticlevels, reducing muscular stimulation andweakening neuromuscular transmission.Inhibit the association of contractileproteins present in muscle cells.· Palmitoyl Tripeptide-5 (SynColl) stimulatesthe synthesis of collagen, elastin, and GAGs,regenerating the dermal matrix. Reduceswrinkles and improves firmness.· Retinol accelerates mitosis, incrementingenzymatic activity and normalizingkeratinization. Stimulates the synthesis ofcollagen and elastin preventing theappearance of wrinkles. Attenuatesblemishes by regulating the proliferationand mobility of altered melanocytes.PROPERTIESContains moisturizing, hydrating, andregenerating ingredients (canola oil,panthenol, rosehip oil evening primrose oiland borage oil) and a DMS® complex(Derma Membrane Structure) with a lipidbase structure similar to That of thestratum corneum.Moisturizes and repairs the skin andstrengthens lipid barrier activity tosupport and retain water.40

therapeutic and complementary | product | peelingtherapeutic and complementary productsKit postratamientoProducts needed by the patient after Nomelan Fenol and Nomelan cafeicotreatments, in order to maintain the results and repair the skin.kitpost-treatmentCOMPOSITION· Nomelan C.· Hidraven soap free foamy cream.· Silkses.· Retises CT Yellow Peel.PROPERTIES· Hidraven soap free foamy creamCream with natural plant extracts. Suitablefor the daily hygiene of sensitive anddelicate skin. 50 ml· Nomelan C post-treatment creamRestorative cream for daily use. Containsmoisturizing, hydrating and regenerativeingredients. 30 ml· Silkses hydrating skin protectorSkin moisturizer formulated with siliconepolymers, vitamins A, C and E and plantextracts (aloe, and mimosa); ingredientsthat facilitate the natural skin regenerationprocess. 30 ml· Retises CT yellow peelRegenerative cream with an exfoliatingaction indicated for the treatment ofphoto-aged, hyper pigmented, and acneprone skins, as well as skins with scars anddistension stretch marks. 5 ml41

peeling | nanotech |nanotechNanotech Professional is a new division belonging to Mediderma. Its products have an innovativeactive ingredient transport and release technology (nanotechnology).Nanosomes are nano-sized vesicles which, by their composition, are completely assimilable byour body. The nanosomes themselves, have resurfacing, anti-inflammatory, antibacterial,clarifying and sebum regulating properties. Thanks to their size, these nanocapsules are capableof transporting active ingredients to the deepest layers of skin.Nanotech professional uses a special technology, a low energy method of producing based onthe physicochemical concepts that the human body uses to produce its own membranes andvesicles, which allows compatibility with a wide variety of active ingredients, that with othertechnologies is not possible due to degradation. In this manner, organic silicon, hyaluronic acid,salicylic acid, vitamins C, A and E, and more, can easily reach the area where they are mosteffective, achieving a better absorption, penetration and diffusion of active ingredients.Nanotech professional makes good use of these advantages and features in its products. Theyinclude ingredients encapsulated in nanosomes, making them unique in the dermocosmeticmarket.42

liposomes | nanotech | peelingliposomesLiposome overview• Extremely small vesicles: 50-200 nm.• Composed of phospholipids organized into bilayers that fold around themselves resulting ina vesicle prepared for the encapsulation and transportation of active ingredients.• The phospholipids contain physiological lipids that repair and restore the barrier function ofthe skin (ceramides, fatty acids, glycerol ...).• Liposomes are similar in composition and structure to that of cell membranes, allowing forthe highest levels of penetration and diffusion of active ingredients.• Allow for the transport of active ingredients (liposoluble and hydrosoluble) in the mostselective way possible: analgesic, antibiotic, anti-inflammatory, vitamin, hydroxy acids, activecosmetics, etc..• Allows for the controlled release of the contained active substances, ehancing the effects ofthe product (prolonged time release).• "Protect" the incorporated active ingredients, and brings greater stability to the formulation.• Thanks to their level of penetration and controlled release, smaller amounts of active ingredientsneed to be used, reducing unwanted side effects (toxicity).• High biocompatibility in different administration routes, topical, systemic, ophthalmic, otic…OUR LIPOSOMESNanotech uses pharmaceutical grade unilamellar liposomes, with a small and homogeneousparticle size (between 50 and 200 nm, depending on the active ingredient and the lipid mixture).ADVANTAGES OVER OTHER LIPOSOMES• Due to their size, higher levels of penetration.• More stable, without stabilizers (cholesterol), allowing them to have a greater aqueous phasevs. lipid phase.• Increased flexibility allows them to adapt to environments of different polarities.INTERNAL AQUEOUSPHASEPHOSPHOLIPIDBI-LAYEREXTERNAL AQUEOUSPHASEElectronic microscope image of unilamellar liposomes43

peeling | product | ferulac peelferulac peelProperties of ferulic acidFerulic acid has antioxidantproperties protecting the skinfrom aggressions caused byfree radicals, inhibiting andneutralizing their effects, andstrengthens the effects ofvitamins C and E. Provides skinprotection from UVB and UVAradiation, helping to minimizedamage from the sun andprotecting the cellular DNA.Controls tyrosinase activity,preventing and clearingunwanted pigmentation. It alsohas a proapoptotic effect incancer cells.Properties of phloretinferulacclassic60 ml - pH 4.5COMPOSITIONferulacplus60 ml - pH 1.5COMPOSITIONferulac nanoadditive mist20 ml - pH 6.5COMPOSITIONPhloretin enhances thepenetration of other activeingredients by adhering to thesurface of lipids and altering thedipole potential of the lipidbilayers. Inhibits elastaseactivity, an enzyme responsiblefor the degradation of elasticfibers. It also has antioxidantproperties.· 12% Ferulic acid.· 5% Phloretin.· 8% Ferulic acid.· 5% Phloretin.· 5% Mandelic acid.· 5% Cutrici acid.· 5% Lactic acid.· 0.2% Retinol.· Ferulic acid.· Phloretin.· Nicotinamide.· Azelaic acid.· Retinol.· Ceramides.· Zinc.INDICATIONINDICATIONINDICATIONPhotoaging.Melasma and sun spots.Photoaging.Melasma and sun spots.Photoaging.Melasma and sun spots.directionsAfter cleaning, degreasing and protecting sensitive areas with a suitable product (Silkses Skin moisturizing protector), apply 2-3 coatsof Ferulac classic peel. Massage the solution until it has dried (observed as a light white mask) to facilitate the penetration of activeingredients. Afterwards apply 2 coats of the Ferulac plus peel, massaging the solution between coats. Apply 1 coat of the Nano Ferulacadditive. After the solution has dried, finish the treatment by sealing the area with Retises nano peel 1% gel. Leave it on the skin foraround 12 hours. After this time, wash with a mild cleansing gel (Hidraven soap free foamy cream).44

salipeel lic | product | peelingProperties of salycilic acidsalipeel licsalicylic acid possesses comedolytic, keratolytic, sebumregulating, anti-inflammatory (inhibits the synthesis ofporstaglandins), antiseptic, antimicrobial, (reducesPropionibacterium acnes) and astringent properties.Properties of ethyl-linoleate and ethyl-citrateEthyl linoleate and ethyl citrate reduce DHT productionby creating an acidic environment which delays the growthof bacteria so bacteria levels are kept under control.salipeellic60 ml - pH 2.0COMPOSITION· Salicylic acid.· Citric acid.· Ethyl-citrate.· Ethyl-linoleate.INDICATIONInflammatory acne.salipeellic nano additive mist20 ml - pH 4.5COMPOSITION· Salicylic acid.· Oleic /linolenic/linoleic acid.· Citric acid.· Nordihydroguaiaretic acid.· Silanols.· Lactoferrin lactoperoxidase.· Zinc.· Ceramides.· Osmose.INDICATIONInflammatory acne.directionsAfter cleaning, degreasing and protecting sensitive areas witha suitable product (Silkses skin moisturizing protector), apply2-3 coats of Salipeel LIC. Massage the solution until it has dried(observed as a light white mask) to facilitate the penetration ofactive ingredients. Then apply 1-2 coats of the Salipeel LIC nanoadditive. After the solution has dried, finish the treatment bysealing the area with Retises nanopeel 1% gel. Leave it on theskin for around 12 hours. After this time, wash with a mildcleansing gel (Hidraven soap free foamy cream).45

peeling | product | retises nanoretises nanoProperties of retinolRetinol is a predecesor of retinoic acid. It acceleratesmitosis, increases enzyme activity and normalizeskeratinization. Nourishes the skin, prevents theappearance of wrinkles, decreases the depth of wrinklesand improves skin elasticity. In addition, retinol attenuatesstains caused by excessive exposure to UV rays, regulatingthe proliferation and mobility of melanocytes. Peeling canbe combined with other anti aging, repairing ordepigmentation treatments (chemical peels, laser, IPL,etc.).retises1% nanopeel gel15 mlRetinol.COMPOSICIÓNretisesnano 1% mist12 mlRetinol.COMPOSICIÓNINDICACIÓNPhotoaging.Melasma and sun spots.INDICACIÓNTreatment of skin aging, acneand hyperpigmentationmanifestations.directionsretises nanopeel 1% gelApply to treatment area or focallyover lesions with a gentlemassage. Let it work for 8 hours.Rinse the treated area.retises 1% mistSpray directly onto the treatmentarea (be careful with the eye area)and make a gentle massage tofacilitate penetration of thesolution. Leave on for 8 hours.Rinse the treated area.46

c-peel | product | peelingc-peelProperties· Vitamin C has a protective action on the skin against radiation,preventing oxidative damage. Stimulates the synthesis of collagen andelastin. Moisturizes the skin, as it promotes the formation of the lipidbarrier in the stratum corneum, contributing to epidermal restructuringand hydration. Inhibits melanogenesis and facilitates epithelialization.· Hyaluronic acid has a natural moisturizing effect on skin to draw watermolecules to the stratum corneum and stimulate the synthesis ofceramides, enhancing and modulating the barrier function.· Mulberry extract inhibits melanogenesis by blocking the tyrosinaseenzyme.· Palmitoyl tripeptide-3 (Syn-Coll ®) stimulates the synthesis of collagen,elastin and GAGs, regenerating the dermal matrix. Reduces wrinklesand improves firmness.· Panthenol reduces inflammation, and has emollient properties thatsoothe and soften irritated skin.c-peeldelivery serum125 mlCOMPOSITION· Vitamine C.· Hyaluronic acid.· Morus alba extract.· Palmitoyl tripeptide-3 (Syn-Coll®).· Panthenol.PROPERTIESTreatment of skin aging, hyperpigmentationand dehydration.directionsCombination with powder additives: With a spatula, mixin a bowl 3.5 gr of powder additive (1/4 ladle) with 7 mlof C-Peel (1/2 ladle). Apply the obtained solution inlayers, massaging the solution between layers.Combination with powder additives and Pyruvic peel:With a spatula, mix in a bowl 3.5gr of powder additive(1/4 ladle) with 7 ml of C-Peel (1/2 ladle) and 7 ml ofPyruvic peel (1/2 ladle). Apply the obtained solution inlayers, massaging the solution between layers.47

peeling | product | masks nanomaskmasks nanomaskRange of professional use face masks, with a bio-cellulose matrix impregnated with activeingredients encapsulated in nanosomes for greater penetration and effectiveness in the skin.Works by optimizing the capacity of active ingredients with direct contact between the maskand the skin through occlusive therapy (increases the penetration of the active ingredientsX10). This is achieved by introducing multiple active ingredients from the epidermis to thedermis, in this way that they work from inside outwards.BIO-CELLULOSE MATRIXMatrix obtained through a natural bacterial fermentation process approved by the OfficialAgency GRAS (Generally Recognized As Safe) with a reticular structure in 3-D with fiber diameterrange of 2 to 100nm.Advantages· Excellent adhesion to the skin.· Allows for long periods of occlusion.· Increased penetration of the active ingredients.· Maximum contact area mask / skin.· Guaranteed safety of use.directions1.- Clean and degreasethe skin.2.- Apply the mask,molding and fitting itto the face.3.- Wait for 20-30minutes.4.- Carefully remove themask and massagethe skin.48

nanomask | product | peelingnanomasknanomaskdaesesnanomaskc-vitnanomaskaloe vera1 unit1 unit 1 unitCOMPOSITION· Dimethylamino etanol (DMAE).COMPOSITION· Ascorbic Acid. · Aloe Vera.· Chitosan.COMPOSITIONINDICATIONINDICATIONINDICATIONFlaccid and / or aged skins.Dull skins, or those lacking brightness.Photoaged skins (wrinkles and pigmentations).Sensitive or irritated skin from medicalprocedures and / or cosmetic treatments(chemical peels, microdermabrasion, laser,photodynamic therapy, etc).PROPERTIES· DMAE improves the firmness of the skin(firming action), stimulates muscle activityproducing stretching with a lifting effect(tensing effect), increases elasticity,reduces wrinkles and stabilizes cellmembranes, repairing the damage causedin collagen by free radicals (antioxidant).PROPERTIES· Vitamin C has a protective action on theskin against radiation, preventing oxidativedamage. Stimulates the synthesis ofcollagen and elastin. Moisturizes the skin,as it promotes the formation of the lipidbarrier in the stratum corneum,contributing to epidermal restructuringand hydration. Inhibits melanogenesis andfacilitates epithelialization.PROPERTIES· Aloe vera penetrates and deeplymoisturizes all layers of the skin, restoringhydrolipidic balance (moisturizing action).It also stimulates the regeneration oftissues and accelerates cellular renewal(epithelializing action), slows microbialgrowth (bacteriostatic action), reducesswelling (soothing action), relieves itchingand reduces pain (anesthetic action).· Chitosan is known for its moisturizing,bacteriostatic and fungistatic properties.49

peeling | product | nanomasknanomasknanomaskcollagen booster1 unitnanomaskyouth booster1 unitCOMPOSITION· Restructuring complex.· Ginkgo Biloba.· Centella Asiatica.COMPOSITION· Collagen.· Soy Isoflavones.· Palmitoyl Tetrapeptide-3.INDICATIONPrevention of skin aging.INDICATIONDry and mature skins.PROPERTIES· Restructuring complex stimulates thefibroblasts to synthesize molecules ofconnective tissue, specifically collagen I,III, IV, fibronectin and glycosaminoglycans.· Centella Asiatica enhances therestructuring complex's stimulatory effecton collagen and GAGs· Ginkgo biloba captures free radicals in theskin, protecting it from premature aging.PROPERTIES· Collagen and palmitoyl tetrapeptide-3stimulate fibroblasts to synthesizecollagen, elastin and GAGs molecules.· Soy isoflavones have antioxidantproperties that protect the skin from theharmful effects of free radicals. Stimulatecell renewal and reduce the degradationof supporting tissue, improving skinelasticity and hydration and reducingwrinkles and flaccidity.50

nanomask | product | peelingnanomasknanomaskplacenses1 unitnanomaskbtses1 unit· Placenta extract.· Silicon.· Hyaluronic acid· Niacinamide.COMPOSITIONINDICATIONAged and / or dehydrated skins.PROPERTIES· Placenta extract rich in peptides andgrowth factors activates cell functions thatstimulate the production of collagen,elastin and GAGs, providing a firmer andmore elastic skin tone.· Silicon helps restructure connective tissueand stimulates fibroblasts to synthesizecollagen, while protecting it from freeradical attacks (glycation activity).· Hyaluronic acid has a natural moisturizingeffect on skin to draw to the watermolecules to the statum corneum andstimulate the synthesis of ceramides,enhancing and modulating the barrierfunction.· Niacinamide has anti-inflammatoryproperties.Relaxing peptides:· Hydrolized Hibiscus Esculentus Extract(Myoxinol®)· Acetyl Glutamyl heptapeptide-1(SNAP-8®)· Acetilhexapeptide 25 (Inyline®)· Pentapeptide-3 (Vialox®)· RetinolCOMPOSITIONINDICATIONYoung skins with expression lines.PROPERTIES· Relaxing peptides act at the presynapticand postsynaptic level, reducing muscularstimulation and weakening neuromusculartransmission. Inhibits the association ofcontractile proteins present in muscle cells· Retinol accelerates mitosis, increasesenzyme activity and normalizeskeratinization. Stimulates the synthesis ofcollagen and elastin preventing theappearance of wrinkles. Reduces spots byregulating and altering the mobility ofmelanocyte proliferation.51

peeling | product | nano mesosolutionsnano meso solutionsnano meso solutionc-vitnano meso solutiondaesesnano meso solutionretises5 x 10 ml 5 x 10 ml 5 x 10 ml 5 x 10 mlnano meso solutionsilorgsesCOMPOSITIONCOMPOSITIONCOMPOSITIONCOMPOSITIONAscorbic acid.Dimethylamino etanol (DMAE)Retinol.Organic silicon.INDICATIONINDICATIONINDICATIONINDICATIONPrevention and treatment of skinphotoaging, melasma, acne andacne scars.Treatment of flaccid and / or agedskins.Treatment of skin aging, acne,hyperpigmentations, acne scarsand stretch marks.Prevention and treatment of skinaging, cellulite, stretch marks,flaccidity and dehydration.PROPERTIESPROPERTIES PROPERTIES PROPERTIES· Vitamin C has a protective actionto neutralize harm from freeradicals, preventing oxidativedamage. Stimulates collagensynthesis and improves skinelasticity. Hydrates the skin, as itpromotes the formation of thelipid barrier of the stratumcorneum, contributing to therestructuring and hydration of theepidermis. Hinders skinpigmentation, inhibitingtyrosinase and facilitatingepithelialization. Reduceserythema and redness caused byUV rays.· DMAE increases the synthesisof acetylcholine, stimulating thecontraction of epidermalkeratinocytes(immediate lifting effect) andmuscle activity (lasting liftingeffect). Regenerates the dermalmatrixfavouring the neoformation ofcollagen and inhibiting proteincross-linking.· Retinol accelerates mitosis,increases enzyme activity andnormalizes keratinization.Prevents and reduces the depthof wrinkles and scars byincreasing the synthesis ofcollagen and reducing levels ofcollagenase. Reduces spots bymodulating the proliferation andmobility of altered melanocytes.Reverses sun damage byrestoring levels of vitamin Adecreased by UVA.· Organic Silicon, a component ofthe extracellular matrix protectsand strengthens elastin andcollagen fibers and proteoglycans.Improves the regeneration processand normalizes cell metabolism inaging tissues. Induces lipolysis bystimulating the hydrolysis oftriglycerides. Reorganizes andstrengthens cell membranesagainst attacks by free radicals andprevents lipid peroxidation. Has ananti-inflammatory action thatdecreases the production ofinterleukins and reduces erythemafrom UV radiation. Maintains thewater level, supporting tissuehydration.52

nano meso solutions | product | peelingnano meso solutionsNano meso solutionsLiposomed range of solutions that have a high doses of activeingredients encapsulated in nanosomes that are unilamellar,felxible, and of uniform size. Designed to work as a transdermalmesotherapy in conjunction with rollers, iontophoresis,sonophoresis, and so on.nano meso solutionplacensesnano meso solutionseskavel mulberry5 x 10 ml 5 x 10 mlCOMPOSITIONPlacenta extract.INDICATIONAging skin and hair-loss treatment.COMPOSITION· Morus Alba Extract.· Nicotinic acid.· Panthenol.· Pyridoxine.· Zinc.INDICATIONPROPERTIES· Placenta extract, rich in peptidesand growth factors activates cellfunctions that stimulate theproduction of collagen, elastin andGAGs, giving firmer and moreelastic skin texture. It stimulateshair growth to enhance bloodcirculation and promotes scalpcapillary respiration. Nourishesand strengthens hair.Hair loss.PROPERTIES· Morus alba extract acts on the haircycle by shortening the telogenphase and stimulating the anagenphase.· Nicotinic acid increases bloodmicrocirculation and improves thesupply of nutrients.· Zinc and vitamin B6 (pyridoxine)inhibit 5-alfa-reductase bypreventing the conversion oftestosterone to dihydrotestosteroneand inhibiting androgenreceptor activity.· Panthenol improves hair quality.Moisturizes and conditions the hair.53

peeling | glossaryglossary· Azelaic acid is characterized by its sebum-regulating (inhibits the5 alpha reductase enzyme), keratinization normalizing,bacteriostatic, oxygen reactive species proliferation inhibiting(present in inflammatory and photo-aging processes) andpigmentation regulating (inhibits the tyrosinase enzyme) properties.· Kojic acid has an antimicrobial effect; its application is useful inthe topical treatment of acne by reducing the P.acnes existent infollicles. It inhibits the synthesis of melanin in various ways, asidefrom blocking tyrosinase, it inhibits tautomerase activity. It haslittle cytotoxic activity, and because of this it can be considered areversible melanogenesis suppressing agent. Additionally it preventsoxidative damage due of its ability to capture reactive oxygenspecies freed on the cells and in tissues, and has solar blockingproperties.· Pyruvic acid (-CO-COOH) is an alpha-keto acid with 3 carbon atoms.It is a medium-strong acid which is present in nature (honey, apples,fermented fruit and vinegar) and in a solution it converts to itscorresponding AHA (lactic acid) and vice versa, a detail which givesit antimicrobial, sebostatic and comedolytic properties. The dermalaction of pyruvic acid makes it useful in skin photo-aging, surfacewrinkles, stretch marks and hyper-pigmentation (melasma)treatments.· Salicylic acid (SA) is a complex that belongs to the beta-hydroxyacid family. It is a well-known agent in dermatology thanks to itskeratolytic and comedolytic properties. The topical application ofSA produces an exfoliation of the surface corneocytes by thedisadhesion or dissolution of the material which acts as anintercellular cement (corneosomes or protein structures). Lysis isproduced layer by layer, from the outer layers down. The exfoliatingeffects of AS made its use popular with hyperkeratosis, as well aswith seborrheic dermatitis, psoriasis, ichthyosis, warts… etc.AS is a liposoluble complex, which allows it to mix with epidermallipids and with the sebaceous material in follicles, facilitating theirelimination, a particularly important effect in acne treatments.Furthermore, this solubility seems to limit the action of salicylicacid to the surface of the epidermis.· Alpha-hydroxy acids or AHA's (glycolic, lactic, citric and mandelicacid…)are a group of acids which occur naturally in nature and arecharacterized by their ability to diminish corneocyte cohesion,although they also possess other useful dermatological therapyeffects. AHAs break the chemical cement unions which bind thecells on the stratum corneum together (corneocytes or dead cells),this allows the cells to loosen and exfoliate. The continuousapplication of high concentrations of AHAs induces a reduction ofthe thickness of the stratum corneum, thickening of the epidermisand the dermis, a restructuring of the differentiation pattern andpolarity of the basal keratinocytes, an increase in collagen depositsand glycosaminoglycans (GAGs) in the papillary dermis and animprovement in the quality of elastin fibers which tend to be longer,less fragmented and more wavy. Furthermore, they decreaseoxidative damage by alleviating the erythema produced afterexposition to the UV rays.· Arginine is an amino acid derived by the fermentation andpurification of plant carbohydrates (sugarcane). They have a largemolecule size which allows for a slow penetration through thestratum corneum, preventing any type of irritation. Exercises ananti-inflammatory action, and has re-hydrating and normalizingeffects on the skin. Stimulates the synthesis of collagen,regenerating the dermal matrix and restoring elasticity and firmnessto the skin, which has been lost due to the passage of time.· Ascorbyl glucoside is a form of stabilized vitamin C (binding aglucose molecule to ascorbic acid reduces the degradation of vitaminC caused by the oxidizing agents, heat, and the presence of metallicions), this helps to preserve its potential biological activity on theskin for a longer time period. Stimulates the synthesis of collagenby fibroblasts, traps free radicals and inhibits skin inflammation,eliminates erythema and the redness caused by UV rays, inhibitsthe synthesis of the melanin in melanocytes, avoiding the formationof un-desired pigments and reduces existing melanin, clarifying theskin.· Hydroquinone, derived from phenol, is the best known as adepigmenting agent. It works by blocking tyrosinase, the enzymewhich controls the formation or synthesis of melanin in themelanocyte. It also can increase the degranulation of mast cells bydisrupting the production of the new pigment. It is usually used inconcentrations of 2-3%, because although a higher concentrationof hydroquinone can increase its effectiveness, it also can increasethe potential corresponding irritation.· Resorcinol an isomeric compound of catechol and hydroquinoneand is related structurally to phenol. Its biggest function isexfoliation. As a bactericide, resorcinol is one-third as active as thephenol. Lower concentration can be used as surface peeling for thetreatment of acne and seborrhea lesions. Higher concentrations canbe used for the treatment of extensive areas such as the back, withsurface or medium penetration.· Retinol is a retinoid precursor of retinoic acid, an organic substancewhich acts as a cell differentiation regulator in different organs andtissues, including the skin. It accelerates mitosis, increases enzymeactivity and normalizes keratinization, improving and acceleratingthe cell renovation process (exfoliating effect) and the generalquality of the skin. Nourishes the skin, prevents the appearance ofthe wrinkles, decreases the depth of existing wrinkles and improvesskin elasticity caused by the passage of time as it stimulates thefibroblasts in order to synthesize connective tissue molecules,specifically collagen. Reduces the level of metalloproteinases inthe dermal matrix, destructive molecules that destroy the structuralintegrity of the skin. Also, retinol lightens spots caused by excessiveUV ray exposure as it regulates the proliferation and mobility ofthe melanocytes.54

www.mediderm.comMEDIDERMA S.L. Pol. Industrial Rafelbuñol. C/ Massamagrell, 3. 46138 Rafelbuñol. Valencia (Spain) Customer service: 902 100 223Pedidos: Tel.: 96 141 42 21 · 96 141 42 20 / Fax: 96 141 40 18 Web: www.mediderm.com e-mail: pedidos@mediderm.com · ses@mediderm.comAUSTRALIA · BELGIUM · BRAZIL · CHINA · CHILE · COLOMBIA · COSTA RICA · DENMARK · DOMINICAN REPUBLIC · CZECH REPUBLIC · EL SALVADOR · ESTONIA · FINLAND · FRANCE · GERMANYGUATEMALA · HONDURAS · INDIA · ITALY · JORDAN · KAZAKHSTAN · KUWAIT · LATVIA · LEBANON · MEXICO · NICARAGUA · NORWAY · PANAMA · PARAGUAY · PHILIPPINES · POLANDPORTUGAL · PUERTO RICO · ROMANIA · RUSSIA · SAUDI ARABIA · SRI LANKA · SLOVAKIA · SWEDEN · TAIWAN · UNITED ARAB EMIRATES · UKRAINE · UNITED KINGDOM · USA · VENEZUELAC7001-1