Final 2007 Antibiogram

(29)48(169)41(25)100(8)63(65)91(139)97(354)94(2043)80(195)100(780)92(77)75(280)81(746)63(167)97(153)76(497)69(316)6(2237)64(1246)43(991)92(577)34(245)99.184(1)0.408(1)0.408Clinical Microbiology Summary of Antibiotic Susceptibility Testing - January 1, 2007 through December 31, 2007Achromobacter xylosoxidansAcinetobacter baumannii/complexAcinetobacter lwoffiiBurkholderia cepaciaCitrobacter freundiiEnterobacter aerogenesEnterobacter cloacaeEscherichia coliHaemophilus influenzaeKlebsiella pneumoniaeMorganella morganiiProteus mirabilisPseudomonas aeruginosaSerratia marcescensStenotrophomonas maltophiliaEnterococcus faecalisEnterococcus faeciumStaphylococcus aureusStaphylococcus aureus (MRSA)Staphylococcus aureus (MSSA)Staphylococcus epidermidisStreptococcus pneumoniae SSIRNo. of IsolatesAmikacinAmoxicillin/clavulanicAmpicillinAmp/sulbactamAztreonamCefazolinCefepimeCefotaxime(non-meningitis)CefotetanCeftazidimeCeftriaxone(non-meningitis)CefuroximeChloramphenicolClindamycinColistinDaptomycinErythromycinGentamicinLevofloxacinLinezolidMeropenemMinocyclineNitrofurantoinOxacillinPenicillinPiperacillin/TazobactamPolymyxin BRifampinSynercidTetracyclineTigecyclineTobramycinTrimeth/sulfaVancomycin291692686513935420431967837728097016715358736822401246994577251(29)28(169)77(26)100(8)0(65)97(139)100(354)99(2043)100(782)98(77)99(280)100(970)79(167)98(12)58(13)15(7)71(16)0(58)5(196)91(24)100(47)0(474)44(275)17(145)0(4)0(64)8(139)1(351)1(2040)51(153)82(781)1(77)1(279)83(167)1(581)99(368)7(2145)3(1238)0(907)8(568)4(29)41(5)0(52)8(133)5(318)4(1976)53(736)74(71)21(108)95(149)2(862)95(817)100(111)68(15)7(132)2(16)0(1)0(53)89(135)81(326)81(1985)96(746)92(73)81(269)94(336)66(155)94(16)0(43)0(7)0(4)0(40)15(125)8(848)85(119)97(65)0(1307)75(980)100(368)29(29)21(61)21(26)50(4)0(65)92(139)99(354)93(2041)97(781)92(77)97(122)92(969)66(167)96(107)100(25)0(51)14(10)70(4)0(14)79(40)85(125)82(844)99(320)91(24)71(119)99(65)69(27)85(1)4(3)11(12)8(13)15(7)71(1)0(58)76(24)100(45)91(28)57(168)36(26)50(8)50(20)85(120)75(309)81(1477)95(619)90(67)81(199)98(962)77(151)87(112)9(27)11(169)17(25)40(63)87(121)75(310)80(1480)96(620)91(67)88(199)99(153)86(245)93(15)6(3)1(15)0(127)0(7)43(63)22(121)4(308)5(1477)88(193)58(67)0(198)97(154)0(469)87(308)97(469)99(265)99(204)100(273)100(55)0(2228)82(1246)73(982)94(572)54(72)99(103)78(242)100(163)100(1939)100(1099)100(840)100(416)100(562)13(362)2(2228)30(1246)6(982)60(572)20(212)46(1)0(113)53(28)14(169)60(25)96(8)0(65)86(139)100(354)95(2043)91(781)94(77)86(280)87(849)67(167)93(2237)97(1246)96(991)98(471)71(587)98(368)96(2235)100(1246)100(989)100(574)100(29)76(169)64(26)100(8)75(65)100(139)99(353)100(2039)100(782)100(77)100(280)100(968)84(167)99(111)98(107)100(1)100(46)80(6)13(3)7(153)97(277)58(15)0(134)1(21)0(4)0(55)98(132)25(329)25(1945)98(733)47(69)4(265)2(155)0(509)99(299)37(1918)100(1072)100(846)100(548)99(2240)44(1246)0(994)100(576)18(583)98(366)7(2174)4(1246)0(928)8(575)2(251)45(94)37(43)17(29)86(139)39(15)80(4)50(63)90(139)78(354)84(2042)96(783)90(77)95(280)96(950)83(166)87(226)97(212)100(67)87(70)100(90)81(472)77(356)9(2233)100(1246)100(987)99(573)95(485)0(355)88(2230)100(1245)99(985)100(573)97(120)45(15)93(52)83(112)91(267)90(1388)74(195)98(563)83(61)49(184)0(129)0(584)25(368)58(2236)97(1246)96(990)97(575)81(208)68(0)0(67)32(4)75(12)75(3)100(41)100(36)100(5)100(29)21(169)67(26)96(8)0(65)83(139)99(354)95(2043)91(781)92(77)88(280)86(970)85(167)83(191)55(27)74(168)46(26)92(8)88(65)80(139)99(354)92(2041)74(195)68(781)90(77)75(280)82(749)12(73)96(153)96(2235)98(1246)98(989)98(309)51(211)61(38)18(45)21(585)98(368)20(2237)100(1245)100(992)100(513)99(47)100(0)0(0)0Data are only forUKMC and are notapplicable to anyother institution.Number inparenthesis = numberof isolates tested.Number listed =% Susceptible.Final 2007 Antibiogram 5/9/08 7:22 AM Page 1

Final 2007 Antibiogram 5/9/08 7:22 AM Page 2DrugUKMC Pharmacy Services Antibiotics Adult Dosing & Cost Relative to Comparable AgentsPenicillins AmpicillinAmoxicillinPenicillin GPenicillin VNafcillinDicloxacillinPiperacillinAmpicillin / Sulbactam (Unasyn)Amoxicillin / Clavulanate (Augmentin)Piperacillin / Tazobactam (Zosyn)Cephalosporins CefazolinCephalexinCefiximeCefuroxime IVCefuroxime POCefprozilCefotaximeCeftraxone (Rocephin)Cefepime (Maxipime)Aminoglycosides GentamicinTobramycinAmikacinMiscelleanous Clindamycin IVClindamycin PO*Doxycycline IV*Doxycyline PO*Erythromycin IV*Erythromycin PO*Azithromycin IV* (Zithromax)Azithromycin PO*Metronidazole IVMetronidazole POTMP / SMX (non-PCP dose)TMP / SMX POVancomycinMeropenem (Merrem)Aztreonam (Azactam)Levofloxacin IV (Levaquin)Levofloxacin POQuinupristin / Dalfopristin* (Synercid)Linezolid IV** (Zyvox)Linezolid PO**Standard Adult Dosing(i.e. Clcr>50 ml / min)I g IV q6h500 mg po q8h1-4 MU IV q4h500 mg po q6h1 g IV q4h500 mg po q6h3 g IV q4h1.5-3 g IV q6h500 mg po q8h3.375 g IV q6h1 g IV q8h500 mg po q6h200 mg po q12h0.75-1.5 g IV q8h500 mg po q12 A500 mg po q12h1 g IV q8h1 g IV q24h1-2 g IV q12h7 mg / kg IV q24h7 mg / kg IV q24h15 mg / kg IV q24h600 mg IV 18h300 mg po q6h100 mg IV q12h100 mg po q12h500 mg IV q6h500 mg IV q6h500 mg IV q24500 mg po q24h500 mg IV q8h500 mg po q8h2.5-5 mg / kg TMP po bid160 mg TMP po bid15 mg / kg IV q12-24h1 g IV q8h1 g IV q8h500 mg IV q24h500 mg po q24h7.5 mg / kg IV q8-12h600 mg IV q12h600 mg po q12hRelative Cost$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$DemoDose and intervals are for moderately severe infections. *No dosage adjustments for renalfailure recommended, must adjust with hepatic impairment.**No dosage adjustments for renal or hepatic failure. Revised 10/04Clinical MicrobiologySummary ofAntibiotic SusceptibilityTestingJanuary 1, 2007throughDecember 31, 2007