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Virtual Box and CMG BioTools Installation Instructions

Virtual Box and CMG BioTools Installation Instructions

Virtual Box and CMG BioTools Installation Instructions

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Preparing for the course, general information.<br />

In order to run the programs used in this course you will need to prepare your computer <strong>and</strong><br />

gain a little knowledge about your computer. Most of the CBS (Center for Biological Sequence<br />

analysis) tools have no graphical interfaces but must be run on a Unix comm<strong>and</strong>-line. The tools<br />

have been collected in a customized operating system, Biotools-xubuntu, that all students will<br />

run on their computers.<br />

IMPORTANT:<br />

• NOTE! It is possible to use Note/Netbooks for the simulations in this course, but it is not<br />

recommended!<br />

• NOTE! Your computer should have a minimum of 4 GB memory free<br />

• NOTE! If xubuntu at any point asks you to update, do NOT update xubuntu.<br />

<strong>Virtual</strong> computer setup.<br />

For this course you will use a virtual computer that works almost like a normal computer. You<br />

will install a program that will allow you to run this virtual computer. You will import a setup<br />

for the computer, a so-called virtual harddisk file, that will hold all the tools you will need for a<br />

basic comparative genomics analysis.<br />

Create a virtual computer on your local hard-drive.<br />

• Download the program virtualbox from this link: http://www.virtualbox.org/wiki/Downloads<br />

(version: select the one that fits your computer).<br />

• Install the program <strong>Virtual</strong><strong>Box</strong> following the installation steps.<br />

• Start the <strong>Virtual</strong><strong>Box</strong><br />

• Click new (the blue icon on the left of the tool bar).<br />

• Type Biotools − xubuntu in the VM name dialog box<br />

• Select linux (Operating system) <strong>and</strong> ubuntu (Version) in the Create New <strong>Virtual</strong> Machine<br />

dialog.<br />

• Leave the Memory form as default<br />

• Select the Biotools-ubuntu.vdi file in the virtual hard disk settings<br />

• Leave virtual disk creation wizard settings unchanged: file type = VDI<br />

• Click create in the Summary dialog.<br />

1


<strong>CMG</strong> biotools set up<br />

• Download <strong>CMG</strong> biotools version 1.3 from the following link;<br />

http://www.cbs.dtu.dk/staff/dave/<strong>CMG</strong>tools/<br />

• In <strong>Virtual</strong><strong>Box</strong> window, click on Settings (the orange icon on the tool bar)<br />

• Select storage on the dialog box<br />

• Click on the CD icon. It will show a CD/DVD Drive dropdown<br />

• Click the CD icon on the right of the dropdown<br />

• Select the iso file (<strong>CMG</strong>-biotools-1.3.iso) from where you have saved it<br />

on your computer<br />

• Click OK. The screen should show the iso file in the storage form<br />

• Click Start to start the virtual machine (The green arrow icon on the tool<br />

bar)<br />

• Select “install – start the installer directly” <strong>and</strong> follow the installation<br />

steps<br />

• Type user name <strong>and</strong> password (You need this password when you log<br />

on to the biotool)<br />

• Restart when it asks.

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