AP 1800™ - Hitachi Chemical Diagnostics

AP 1800
AUTOMATED IN VITRO ALLERGY
DIAGNOSTIC SYSTEM
Helping the medical community provide
quality and affordable allergy care.

The future of
allergy-specific
IgE panel testing
automation.
The AP 1800 from
Hitachi Chemical
Diagnostics.
Industry-leading throughput of allergen tests. An extended reporting range of up
to 6 classes. For up to fifty patients per run. All fully automated, in an easy-touse,
reliable design, backed by over twenty years of pioneering innovation and
support, world-wide. A new dimension in allergy diagnostics from Hitachi
Chemical Diagnostics (HCD).
HCD’s AP 1800 system for in vitro allergy testing
provides test results in less than six hours. With
complete automation and software that can support
multiple tasks and an easy-to-use, intuitive interface,
the AP 1800 provides a reliable and cost-effective
walk-away solution.
Built on HCD's unique allergy panel format, the
AP 1800 provides a compact tabletop design,
with the full capabilities and data management of
much larger, more costly instruments. The AP 1800:
the most complete profile for the medical community
and allergy patients.
The AP 1800 is based on proven CLA reagent and Hitachi clinical
instrumentation technology.

Industry-Leading Performance
Based on proven CLA ® reagent technology, the AP 1800 provides a high
correlation with an established in vitro method and skin prick testing
over an extended reporting range.
Advanced Intuitive Interface and Software
The AP 1800 allows staff to stay productive and report results more rapidly.
With HCD’s flexible software, the technician can review results, prepare the
next run, or evaluate quality controls while the system continues to function.
The Windows operating system allows technicians with little specialized
training to manage the AP 1800 with ease. With a bi-directional interface and
bar code readers for both patient samples and allergen panels, the AP 1800
minimizes time spent in pre- and post-analytical phases of testing, and
reduces clerical activity.
Enhanced Reliability
With very few moving parts, the AP 1800 is designed for reliability,
providing maximum uptime.
Compact Design
Bench-top design occupies just 92 by 77 centimeters, making the most
of often-limited laboratory space.
Set Up Hour 0
Hour 1
Patient Samples
Allergen Panels
Reagents &
Wash Buffer
Serum Aspiration
Serum Incubation
Fast and accurate results with industry leading throughput and data
management capacity of more than 10,000 tests and 500 physicians.

Functional Specifications
Capacity
• 1500 allergens per run, for up to fifty patients (fifty tests/run, two runs/day)
• Less than six hour assay time
• Six class system
• Up to five allergen panels per run selected by patient sample
• Data management for up to 10,000 tests and 500 physicians
Physical Specifications
• Size (without PC): 61 x 92 x 77 centimeters; less than 70 kg, with self-contained
fluid and waste systems
Technical Specifications
• Built in bar code readers for both patient sample cups and allergen panels
• Easy-to-use Order Entry, Data Review and QC software
• One reagent set for all allergen panels
• CE marked
• Universal power supplies
Software
• Windows operating system
• Easy-to-use QC control software
• Multi-language (5 languages) capability
• Easily archive data to CD
Options
• Easy laboratory information systems connection
1 Hour 2
AP 1800 Walk Away Instrument
Washing
Conjugate Aspiration
Conjugate Incubation
Operator Hands-On
Hour 3 Hour 4 Hour 5 Hour 6
Walk-away
Washing Maintenance
Photoreagent Aspiration
Patient Results
Prepare Next Run
Review Previous
Patient Data
Review QC Data
Easy-to-use, the AP 1800 maximizes resources and minimizes
hands-on time, allowing staff to perform other duties.

AP 1800 Performances
In Vitro Allergy Method Comparison
The performance of the AP 1800 has been evaluated in several studies,
including those run at HCD and beta site evaluations. All evaluations
were performed against another in vitro method. The results show a
sensitivity of 91%, a specificity of 83% and an efficiency of 87% with
a total of 2700 data points.
Reference Method
+ –
AP 1800 + 1100 249
AP 1800 –
Precision
103
Intra-Assay: Five replicates of three serum samples were run on four days.
The mean of the coefficient of variation from all of the allergens tested,
when calculated as net LUs, was 11.9%.
Inter-Assay: Three single serum samples were run on four days. The mean
of the coefficient of variation from all of the allergens tested, when calculated
as net LUs, was 13.5%.
With its compact, tabletop design, the AP 1800 makes
the best use of valuable laboratory space.
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With its headquarters in the heart of Silicon Valley and offices around the world, Hitachi Chemical Diagnostics is a
global leader of in vitro allergy diagnostics with a legacy of innovation. Hitachi Chemical Diagnostics was the first
company to introduce a multiple diagnostic test for allergies and one of the first to introduce a chemiluminescent
assay system for the detection of lgE antibodies, the CLA ® Allergy Test.
Hitachi Chemical Diagnostics, an integral member of the Hitachi Group, works with industry leaders, laboratories
and distributors around the world to provide the medical community access to the latest in vitro allergy testing
technology. Hitachi Chemical Diagnostics is committed to innovation, quality, and the strength of the Hitachi brand.
Our products are marketed to over 40 countries worldwide. To learn more about Hitachi Chemical Diagnostics and
AP 1800, please contact us or your local representative, or visit us on the web at www.hcdiagnostics.com.
United States Office
630 Clyde Court
Mountain View
CA 94043-2239
650.961.5501
800.233.6278
www.hcdiagnostics.com
©2004 Hitachi Chemical Diagnostics, Inc. All rights reserved.
Doc. No. 0626 Rev. 01
European Office
Hitachi Europe Ltd.
Whitebrook Park
Lower Cookham Road
Maidenhead, Berkshire, SL6 8YA
United Kingdom
44 (0) 1628.585.590