12.07.2015 Views

Respiratory Failure in Children - Nemours

Respiratory Failure in Children - Nemours

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RESPIRATORY FAILURETime Constants# Time required for lung unit to fill to 63% of f<strong>in</strong>al volume.# Time constant = Resistance x Compliance# Those alveoli with shorter time constants fill faster.# Local variation <strong>in</strong> resistance and compliance effect gasdistribution.# e.g. overall TC is <strong>in</strong>creased <strong>in</strong> Asthma

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