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Success Will Rest With the ability to:•Identify and validate nutrigenetic,nutritional epigenetic & transcriptomic,proteomic and metabolomic biomarkers ofeffect and susceptibility•Communicate effectively its values to thehealth care community and consumers•Ensure a responsible bioethical framework
Page 2: Unprecedented opportunities exist f
Page 5 and 6: Surrogate markerIs a response varia
Page 7 and 8: SYSYTEMS BIOLOGY APPROACH TOBIOMARK
Page 9 and 10: Pathway of DiseaseNatural History o
Page 11 and 12: Biomarkers and Other IntermediateId
Page 13 and 14: Three Types Biomakers NeededExposur
Page 15 and 16: Epidemiologic Studies of Soy Compon
Page 17 and 18: Tissue and Leukocyte IQ-DNA Adducts
Page 19 and 20: Bronchodilator Response to Albutero
Page 21 and 22: The “Omics” of Nutrition and Ef
Page 23 and 24: Influence of Caffeine on Bone Mass
Page 25 and 26: Nutrigenomics today!• Commercial
Page 27 and 28: % Reduction in LDL Cholesterol as a
Page 30 and 31: MULTIPLE PATHWAYSEBDMOne Pathway: A
Page 32 and 33: • Tomatoes• Spinach• Broccoli
Page 34 and 35: Components are “complexmixtures
Page 36 and 37: Similar to Drugs One Size Does Not
Page 38 and 39: Life Style Issues• What are appro
Page 40 and 41: Nutritional Preemption(A Strategy f

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