1. COMPUTER ARCHITECTURE & ORGANIZATION: Combinational ...

ENTRANCE EXAMINATION SYLLABUS FOR PhD (2014)1) Clinical Pharmacology :Principles of Basic Pharmacology, Pharmacokinetics(ADME), Pharmacodynamics (mechanism of Action),Toxicity Studies, DoseResponse relationship, Therapeutic index, Neurological disorders, malignantdiseases, Infectious diseases,Reference Book: Essentials of Medical Pharmacology- K.D Tripathi,Basic Principles of Internal Medicine by Harrison, Mc Graw Hills publishers2) Fundamentals of Clinical Research :Drug Discovery and Development, Historyof Clinical Research, Indian Regulation (Schedule Y), Drug and Cosmetic Act,ICMR Guidelines, Worldwide Regulations(ICH-GCP, US FDA), Introduction toClinical Data Management , Process of Data management, Data Validation,Medical CodingReference Book: Basic Principles of Clinical research and Methodology by S.KGuptaICMR, FDA and CDSCO websites.3) Biostatistics : Basic Definition and Application, Types of Data (Nominal Data,Ordinal data, Ranked Data, Discrete Data, Continuous Data ) ,Measures ofCentral Tendency (Mean, Median, Mode), Measures of Dispersion(Variance ,standard Deviation, Coefficient Of variance ), Parametric and Non-ParametricTests, Hypothesis Testing, Probability, Frequency DistributionReference Book: Principles of Biostatistics by Marcello Pagano4) Pharmacogenomics : Importance of Study in Pharmacogenomics,Pharmacogenetic Phenotypes, Gene Therapy ,Classification of Enzymes ,Basic aspects of Enzyme Kinetics, Recombinant DNA Technology, Cellularorganization, DNA Replication, Immunity, Analytical TechniquesReference Books: Pharmacogenomics introduction and Clinical perspective byJoseph.S.BertinoConcepts in Pharmacogenomics by Zdanowicz