Programm A4 - Österreichische Gesellschaft für Allergologie und ...
Programm A4 - Österreichische Gesellschaft für Allergologie und ...
Programm A4 - Österreichische Gesellschaft für Allergologie und ...
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
<strong>Österreichische</strong> <strong>Gesellschaft</strong> <strong>für</strong> <strong>Allergologie</strong> <strong>und</strong> Immunologie<br />
&<br />
Deutsche <strong>Gesellschaft</strong> <strong>für</strong> Immunologie<br />
JOINT ANNUAL MEETING<br />
OF IMMUNOLOGY<br />
OF THE<br />
AUSTRIAN AND GERMAN SOCIETIES<br />
Lecture Centre of the Vienna General Hospital<br />
Vienna, Austria<br />
Wednesday, September 3 – Saturday, September 6, 2008<br />
Final <strong>Programm</strong>e<br />
www.medacad.org/oegai2008
ALLERGIE LAUF<br />
Sonntag, 7. September 2008<br />
Schlosspark Schönbrunn<br />
Hiermit laden wir Sie ganz herzlich dazu ein, im Anschluss an den Kongress<br />
„Joint Annual Meeting of Immunology, Wien, 3.-6. September 2008“, am<br />
ALLERGIE LAUF am Sonntag, 7. September 2008<br />
im SCHLOSSPARK SCHÖNBRUNN,<br />
einer der schönsten Parkanlagen Wiens, teilzunehmen.<br />
Nach dem Startschuss von Nobelpreisträger Peter Doherty geht es durch den Schlosspark Schönbrunn,<br />
durch Alleen mit barocker Gartenbaukunst, <strong>und</strong> vorbei am Schloss Schönbrunn, einem der bedeutendsten<br />
Kulturdenkmäler Österreichs, einst bewohnt von Kaiserin Sissi <strong>und</strong> heute ein beliebtes Ausflugsziel vieler<br />
Wiener <strong>und</strong> Wienbesucher.<br />
Sie können unter verschiedenen Distanzen wählen <strong>und</strong> auch im Team laufen. Das Tempo bleibt Ihnen<br />
überlassen: gemütlich oder mit sportlichem Ehrgeiz, dazu wird es eine exakte elektronische Zeitmessung<br />
geben. Ob Kongressteilnehmer oder nicht - es sind alle eingeladen, mit zu laufen.<br />
Im Anschluss an den Lauf folgen als Krönung des Tages <strong>und</strong> als Belohnung <strong>für</strong> Ihren sportlichen Einsatz<br />
<strong>und</strong> das tüchtige anfeuern Ihrer Fans, die After Running Party, die Siegerehrung, eine Tombola, ein<br />
Buffet reich an köstlichen typisch österreichischen Gerichten, <strong>und</strong> eine Musikshow. Es unterhalten<br />
Sie Harry Sonnek <strong>und</strong> der legendäre Dave Dee, der mit seinen besten Songs aus den 60ern aus London<br />
zu uns kommen wird <strong>und</strong> <strong>für</strong> die richtige Partystimmung sorgen wird. Zur After Running Party sind alle<br />
Läufer <strong>und</strong> deren Begleiter ganz herzlich eingeladen.<br />
Bitte nutzen Sie die Möglichkeit der Online-Anmeldung auf www.medacad.org/oegai2008 unter „Allergy<br />
Run“ sobald als möglich, damit Sie sich Ihr, in der Gebühr inkludiertes, Erinnerungs- T-Shirt in der<br />
richtigen Größe sichern.<br />
Auf der Homepage finden Sie auch alle mit dem Lauf verb<strong>und</strong>enen Informationen, sowie den vorläufigen<br />
Streckenplan.<br />
Wir freuen uns auf zahlreiche Anmeldungen!<br />
www.b<strong>und</strong>esgaerten.at
<strong>Österreichische</strong> <strong>Gesellschaft</strong> <strong>für</strong> <strong>Allergologie</strong> <strong>und</strong> Immunologie<br />
&<br />
Deutsche <strong>Gesellschaft</strong> <strong>für</strong> Immunologie<br />
JOINT ANNUAL MEETING<br />
OF IMMUNOLOGY<br />
OF THE<br />
AUSTRIAN AND GERMAN SOCIETIES<br />
Lecture Centre of the Vienna General Hospital<br />
Vienna, Austria<br />
Wednesday, September 3 – Saturday, September 6, 2008<br />
Final <strong>Programm</strong>e<br />
www.medacad.org/oegai2008
Table of Contents<br />
General<br />
Patronage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2<br />
Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2<br />
Welcome Addresses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3<br />
Committees – Board – Organisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5<br />
<strong>Programm</strong>e at a Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6<br />
Scientific <strong>Programm</strong>e<br />
- Wednesday, September 3, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8<br />
- Thursday, September 4, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9<br />
- Friday, September 5, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15<br />
- Saturday, September 6, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20<br />
Poster Viewing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25<br />
Business Meetings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26<br />
Satellite Lunch Symposia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27<br />
Information on Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28<br />
Information for Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29<br />
Information<br />
Congress Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30<br />
Registration Fees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32<br />
General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33<br />
Venue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35<br />
Social Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37<br />
Undergro<strong>und</strong> Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38<br />
City Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39<br />
Exhibition<br />
Exhibition – General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40<br />
List of Sponsors, Exhibitors and Advertisers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41<br />
1
Patronage<br />
Under the Patronage of<br />
Dr. Alfred Gusenbauer<br />
Federal Chancellor of the Federal Republic of Austria<br />
Dr. Johannes Hahn<br />
Federal Minister for Science and Research<br />
Dr. Andrea Kdolsky<br />
Federal Minister for Health, Family and Youth<br />
Mag. Sonja Wehsely<br />
Executive City Councillor for Public Health and Social Affairs<br />
Acknowledgements<br />
The Joint Annual Meeting of Immunology gratefully acknowledges the support of the following<br />
institutions, companies and organisations (list correct as per date of printing):<br />
2
Welcoming Addresses<br />
Unquestionably a high level of health care is the core element of our modern<br />
welfare system as we know it. It is therefore our duty as politicians to secure<br />
the basis for its long-term financial stability. Furthermore, we must create an<br />
institutional and legal framework to guarantee universal and non-discriminatory<br />
access to all forms of treatment. Nobody should be excluded or left<br />
behind. Only <strong>und</strong>er these conditions can health-care professionals fulfil their<br />
essential duty and live up to their oath i.e. helping people.<br />
Public opinion polls show the high satisfaction of Austrians with our national<br />
health care system. But no society can satisfy itself with self appreciation. Many challenges lie<br />
ahead of us. Some are institutional, financial, others are scientific. This congress will help to promote<br />
knowledge and hopefully inspire all working in your field.<br />
On behalf of the Austrian government it is my pleasure to welcome you here in Austria and in<br />
particular at this “Joint Annual Meeting of Immunology”.<br />
Dr. Alfred Gusenbauer<br />
Federal Chancellor of the Federal Republic of Austria<br />
More than 1000 participants at the „Joint Annual Meeting of lmmunology"<br />
give invigorating proof of the importance and international reputation of the<br />
Societies of Allergology and Immunology in Austria and Germany on the one<br />
hand and the Vienna Medical Academy in the fields of education/research as<br />
well as conference and association management – an organisation dedicated<br />
to serving the needs of the medical non-profit community - on the other. As<br />
minister of Science and Research it is good news for me that international<br />
experts are discussing such pressing topics as vaccination, infection and<br />
allergy just now in Austria. That means new incentives for the Scientific Community<br />
especially in our country and the opportunity to expand international networking. These<br />
issues are of great relevance for nearly all of us and the expectations are very high, if you only think<br />
of tumor immunology for example. May the meeting be a successful one with impressing results<br />
and congratulations on bringing together university professors of international reputation in this<br />
field in Vienna for the first time. In this way the meeting is a great recognition of Vienna as an important<br />
medical research place.<br />
Dr. Johannes Hahn<br />
Federal Minister for Science and Research<br />
3
Welcoming Addresses<br />
Dear colleagues and scientific friends,<br />
It is our great pleasure to welcome you to the Joint Annual Meeting of the Austrian and the German<br />
Societies of Immunology in Vienna.<br />
The annual conferences of our societies allow for an exchange of thoughts and information on cutting<br />
edge developments taking place in the immunological laboratories worldwide. The format of<br />
a joint annual conference allows for an expansion of this exchange into a neighbouring country<br />
and likewise fosters new and/or permits to renew longstanding scientific and social relationships.<br />
With this meeting we are aiming to delineate the latest progress in our field, focusing on matters<br />
arising not only in basic innate and adaptive immunity, but also clinical immunology including<br />
novel therapeutic approaches. The scientific committee has invited outstanding scientists to present<br />
their thinking and to summarize data on their advances in plenary sessions and introductions<br />
to workshops. Within workshops and during the poster sessions, there will be ample opportunity<br />
especially for students and postdoctoral fellows to present their newest research results and thus<br />
a broad array of work which is performed in the realm of the hosting societies and beyond.<br />
We have made all efforts to create a scientific program that meets your expectations. In addition<br />
you shall enjoy Vienna´s ambience and hospitality, the unique culture and spirit which so few<br />
other cities have to offer.<br />
With best wishes for a scientifically exciting and<br />
stimulating meeting and<br />
mit herzlichen Grüßen,<br />
Yours<br />
Stefan Meuer & Josef Smolen<br />
4
Committees – Board – Organisation<br />
Congress Committee<br />
Stefan C.W. Meuer Josef Smolen<br />
Andreas Radbruch Marcus Säemann<br />
Reinhold E. Schmidt<br />
Local Organising Committee<br />
Irmgard Förster Marcus Säemann<br />
Beatrix Grubeck-Loebenstein Reinhold Schmidt<br />
Erika Jensen-Jarolim Josef Smolen<br />
Stefan C.W. Meuer Hannes Stockinger<br />
Winfried Pickl Rudolf Valenta<br />
Andreas Radbruch Gerhard Zlabinger<br />
ÖGAI Executive Committee<br />
Josef Smolen (President) Gernot Achatz (Board Member)<br />
Rudolf Valenta (President Elect) Hans-Peter Brezinsek (Board Member)<br />
Beatrix Grubeck-Loebenstein (Past President) Roswitha Gruber-Sgonc (Board Member)<br />
Marcus Säemann (Secretary General) Erika Jensen-Jarolim (Board Member)<br />
Winfried Pickl (Deputy Secretary) Johannes Stöckl (Board Member)<br />
Tamara Kopp (Secretary Protocol) Martin Thurnher (Board Member)<br />
Barbara Bohle (Treasurer) Othmar Förster (Honorary President)<br />
DGfI Executive Committee<br />
Stefan C.W. Meuer (President) Reinhold Förster (Board Member)<br />
Andreas Radbruch (President Elect) Stefan H. E. Kaufmann (Board Member)<br />
Reinhold E. Schmidt (Past President) Heidrun Moll (Board Member)<br />
Werner Solbach (Secretary General) Yvonne Samstag (Board Member)<br />
Christian Bogdan (Board Member) Burkhart Schraven (Board Member)<br />
Barbara Bröker (Board Member) Hans Dieter Volk (Board Member)<br />
Stefan Ehlers (Board Member)<br />
Irmgard Förster (Board Member)<br />
Hans-Martin Jäck (Board Member)<br />
Conference Organisation, Abstract Management, Sponsoring<br />
Vienna Medical Academy<br />
Ms. Marieke Hodel<br />
Alser Strasse 4, 1090 Vienna, Austria<br />
Phone: +43 1 405 1383-10; Fax: +43 1 407 8274<br />
E-mail: oegai2008@medacad.org<br />
Exhibition Management Hotel Accomodation<br />
Medizinische Ausstellungs- <strong>und</strong> Mondial Congress & Events<br />
Werbegesellschaft MAW Operngasse 20b<br />
Freyung 6 1040 Vienna<br />
A-1010 Vienna, Austria Phone: +43 1 58804-0<br />
Phone: +43 1 536 630 Fax: +43 1 58804-185<br />
Fax: +43 1 535 60 16<br />
E-mail: maw@media.co.at<br />
Email: oegai2008@mondial-congress.com<br />
Congress Venue<br />
Lecture Centre of the Vienna General Hospital<br />
(Allgemeines Krankenhaus - AKH)<br />
Währinger Gürtel 18-20<br />
1090 Vienna, Austria<br />
5
<strong>Programm</strong>e at a Glance<br />
Wednesday, September 3, 2008<br />
Time Lecture Hall 1<br />
Welcome and Opening<br />
Stefan Meuer, President DGfI<br />
Josef Smolen, President ÖGAI<br />
15.00 –<br />
15.10<br />
Karl Landsteiner (1868-1943) - An Austrian Immuno-Pathologist (G. Schmidt-Wyklicky)<br />
Awarding of the Landsteiner Price of the DGfI to Max Cooper<br />
Awarding of the Landsteiner Medal of the ÖGAI to Ron Germain<br />
Vienna Philharmonic<br />
Keynote Lecture: Nobel Laureate Peter Doherty<br />
Vienna Philharmonic<br />
Opening by Wolfgang Schütz (Rector of the Medical University of Vienna)<br />
15.10 –<br />
15.25<br />
15.25 –<br />
15.45<br />
15.45 –<br />
16.05<br />
16.05 –<br />
16.20<br />
16.20 –<br />
16.50<br />
16.50 –<br />
17.00<br />
17.00 –<br />
17.15<br />
Followed by Welcome Drinks<br />
Thursday, September 4, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
Parallel Symposium 1:<br />
08.15 – Parallel Symposium 1:<br />
Parallel Symposium 1:<br />
Innate Immunity: Antigen-Presenting-<br />
09.30 T-Cell Signaling<br />
Tumor Immunology<br />
Cells<br />
Break & Poster Viewing<br />
Innate Immunity: Antigen-Presenting<br />
Cells<br />
T-Lymphocytes I Autoimmunity I Tumor Immunology Immunomodulation<br />
09.30 –<br />
10.30<br />
10.30 –<br />
12.15<br />
Satellite Lunch Symposium:<br />
B cell: Promising target in autoimmune<br />
diseases (Roche)<br />
T-Lymphocytes II Vaccines & Adjuvants Signal Transduction NK cells Veterinary Immunology<br />
12.15 –<br />
13.45<br />
14.00 –<br />
15.30<br />
15.30 –<br />
Break & Poster Viewing<br />
16.30<br />
16.45 – Parallel Symposium 2:<br />
Parallel Symposium 2:<br />
Parallel Symposium 2:<br />
18.00 Vaccination<br />
In vivo imaging<br />
Immunomodulation<br />
19.00 Welcome Reception at the Vienna City Hall<br />
6<br />
Plenary Session Parallel Symposium Workshops Satellite Lunch Symposium
<strong>Programm</strong>e at a Glance<br />
Friday, September 5, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
08.15 – Parallel Symposium 1:<br />
Parallel Symposium 1:<br />
Parallel Symposium 1:<br />
09.30 Innate Immunity: Regulation<br />
Mucosal Inflammation<br />
Transplantation<br />
09.30 –<br />
Break & Poster Viewing<br />
10.30<br />
10.30 –<br />
Pattern Recognition Receptors &<br />
Allergy I Regulatory Lymphocytes I Alloimmunity & Tolerance<br />
Innate Immunity: Regulation<br />
12.15<br />
Myeloid Cells<br />
12.15 –<br />
Satellite Lunch Symposium:<br />
13.00<br />
Immune modulation with intravenous<br />
13.00 – Drittmittelförderung der DFG: Kriterien immunoglobulin: the established and<br />
13.45 <strong>für</strong> eine erfolgreiche Antragstellung the advances (Octapharma)<br />
14.00 –<br />
Infection I Allergy II Regulatory Lymphocytes II Mucosal Immunity B-Lymphocytes<br />
15.30<br />
15.30 –<br />
Break & Poster Viewing<br />
16.30<br />
16.45 – Parallel Symposium 2:<br />
Parallel Symposium 2:<br />
Parallel Symposium 2:<br />
18.00 Infection<br />
Adaptive Immunity: Regulation Adaptive Immunity: B-Cells<br />
18.00 –<br />
General Assembly DGfI<br />
19.30<br />
19.30 Departure with buses to the Viennese “Heuriger” Fuhrgassl-Huber<br />
Saturday, September 6, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
08.45 – Parallel Symposium 1:<br />
Parallel Symposium 1:<br />
Parallel Symposium 1:<br />
10.00 Autoimmunity<br />
Inflammation<br />
Allergy<br />
10.00 –<br />
Break<br />
10.30<br />
10.30 –<br />
Cytokines, Chemokines & their<br />
Satellite Lunch Symposium:<br />
Autoimmunity II Infection II Complement System<br />
12.15<br />
receptors<br />
Vom rekombinanten Allergen zu<br />
12.15 –<br />
neuen Allergietherapien (Phadia)<br />
12.45<br />
Break<br />
12.45 –<br />
Break<br />
13.00<br />
13.00 – Klinische Fälle aus der <strong>Allergologie</strong>:<br />
13.45 Wie hätten Sie entschieden?<br />
14.00 –<br />
Best Poster Awards<br />
14.30<br />
15.00 General Assembly ÖGAI<br />
7<br />
Plenary Session Parallel Symposium Workshops Satellite Lunch Symposium
Scientific <strong>Programm</strong>e – Wednesday, September 3, 2008 8<br />
Time Lecture Hall 1<br />
15.00<br />
-<br />
15.10<br />
15.10<br />
-<br />
15.25<br />
15.25<br />
-<br />
15.45<br />
15.45<br />
-<br />
16.05<br />
16.05<br />
-<br />
16.20<br />
16.20<br />
-<br />
16.50<br />
16.50<br />
-<br />
17.00<br />
17.00<br />
-<br />
17.15<br />
Welcome<br />
Chair: S. Meuer, J. Smolen<br />
Welcoming addresses by<br />
Stefan Meuer, President DGfI<br />
Josef Smolen, President ÖGAI<br />
Karl Landsteiner (1868-1943) - An Austrian Immuno-Pathologist<br />
Gabriela Schmidt-Wyklicky<br />
Awarding of the Landsteiner Price of the DGfI to Max Cooper<br />
Laudatio: Andreas Radbruch<br />
Award Lecture: Max Cooper<br />
Awarding of the Landsteiner Medal of the ÖGAI to Ron Germain<br />
Laudatio: Clemens Scheinecker<br />
Award Lecture: Ron Germain<br />
Rainer Honeck, Concert Master of the The Vienna Philharmonic Orchestra: J.S. Bach<br />
Keynote Lecture:<br />
Nobel laureate Peter Doherty<br />
Rainer Honeck, Concert Master of the Vienna Philharmonic Orchestra: F. Kreisler<br />
Opening by Wolfgang Schütz (Rector of the Medical University of Vienna)<br />
17.15 Welcome Drinks
Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 9<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />
08.15<br />
-<br />
09.30<br />
09.30<br />
-<br />
10.30<br />
Parallel Symposium 1:<br />
T-Cell Signaling<br />
Chair: W. Pickl, D. Kabelitz<br />
Molecular determinants of Inside-out<br />
signaling in T-cells<br />
B. Schraven<br />
From T cell activation signals to signaling<br />
control of anti-cancer immunity<br />
J. Penninger<br />
Deciphering TCR ligand discrimination by<br />
combining experiments, computer<br />
modeling, and predictive simulations<br />
R. Germain<br />
Parallel Symposium 1:<br />
Innate Immunity: Antigen-Presenting-<br />
Cells<br />
Chair: G. Stingl, B. Broeker<br />
DC dependent maintenance of peripheral<br />
regulatory T-cells<br />
S. Beissert<br />
Role of antimicrobial peptides in triggering<br />
autoimmunity<br />
M. Gilliet<br />
TLR-activated dendritic cells as effector<br />
cells of the immune response<br />
G. Stingl<br />
Coffee Break / Poster Viewing / Exhibition<br />
Parallel Symposium 1:<br />
Tumor Immunology<br />
Chair: E. Jensen-Jarolim, G. Riethmüller<br />
Human Self/Tumor Antigens and Tumor<br />
Immunosurveillance<br />
O.J. Finn<br />
The immune response to sporadic cancer<br />
T. Blankenstein<br />
Development of DNA vaccination strategies<br />
for pediatric cancers<br />
H.N. Lode
Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 10<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
10.30<br />
-<br />
12.15<br />
T-Lymphocytes I<br />
Chair: G. Schütz,<br />
H. Wolf<br />
1. Increased Th17 and<br />
decreased CD4+FoxP3+<br />
T regulatory cells in third<br />
trimester pregnancies<br />
with pre-eclampsia<br />
B. Santner-Nanan,<br />
M. Peek, L. Richarts,<br />
R. Khanam, E. Zhu, B.<br />
Fazekas de St. Groth,<br />
R. K. Nanan<br />
2. Blockade of inducible<br />
costimulator (ICOS) inhibits<br />
accumulation of<br />
polyfunctional<br />
Th1/Th17cCells and prevents<br />
autoimmune arthritis<br />
O. Frey, J. Meisel,<br />
L. Bruns, A. Hutloff,<br />
L. Morawietz, T. Kamradt<br />
3. IRF4 is essential for<br />
IL-21-mediated induction,<br />
amplification and<br />
stabilization of the Th17<br />
phenotype<br />
M. Huber, A. Brüstle,<br />
A. Guralnik, A. Mahiny,<br />
E. von Löw, M. Lohoff<br />
4. Acid sphingomyelinase<br />
is a critical regulator<br />
of cytotoxic granule<br />
secretion by primary T<br />
lymphocytes<br />
J. Herz, J. Pardo,<br />
H. Kashkar,<br />
M. Schramm,<br />
E. Kuzmenkina, E. Bos,<br />
K. Wiegmann,<br />
R. Wallich, P. J. Peters,<br />
S. Herzig, E. Schmelzer,<br />
M. Krönke, M. M. Simon,<br />
O. Utermöhlen<br />
5. Adenosine regulates<br />
CD8 T cell priming by inhibition<br />
of membraneproximal<br />
T cell receptor<br />
signaling<br />
D. Stabenow,<br />
C. Linnemann,<br />
F. A. Schildberg,<br />
A. Schurich,<br />
S. I. Hegenbarth,<br />
L. Diehl, E. Endl,<br />
S. Lacher, C. E. Müller,<br />
J. Frey, L. Simeoni,<br />
L. Simeoni, B. Schraven,<br />
P. A. Knolle<br />
6. pSMAC formation in<br />
human peripheral blood<br />
T-cells requires localization<br />
of the actin-b<strong>und</strong>ling<br />
protein L-plastin to the<br />
immunological synapse<br />
G. Wabnitz, P. Lohneis,<br />
H. Kirchgessner,<br />
Y. Samstag<br />
Autoimmunity I<br />
Chair: H. Strobl,<br />
G. Beilhack<br />
9. The role of B cells in<br />
tissue draining lymphnodes<br />
for the development<br />
of collagen<br />
induced arthritis (CIA)<br />
C. Scheinecker,<br />
A. Rapp, M. Bonelli,<br />
A. Savitskaya,<br />
J. S. Smolen<br />
10. T helper cells only induce<br />
acute inflammation<br />
but B cells are necessary<br />
for the induction of<br />
chronic Antigen-induced<br />
Arthritis<br />
M. Janke, T. Hohnstein,<br />
L. Morawietz,<br />
A. Scheffold<br />
11. Crucial role of CCR4<br />
in the development of<br />
experimental CNS autoimmune<br />
disease by<br />
modulation of Treg cell<br />
compartimentalization<br />
J. Alferink, D. M. Otte,<br />
K. Poppensieker,<br />
Ö. Yilmaz, A. Mildner,<br />
M. Prinz, W. Maier,<br />
A. Zimmer<br />
12. Antigen-specific<br />
TGF -induced Treg suppress<br />
Th17-mediated<br />
autoimmune disease<br />
E. N. Huter,<br />
G. H. Stummvoll,<br />
E. M. Shevach<br />
13. The pathogenic role<br />
of HnRNP-A2 in Pristane-induced<br />
arthritis<br />
M. H. Hoffmann, C.<br />
Baumann, B. Meyer,<br />
G. Steiner<br />
14. The autoimmune regulator<br />
Roquin-a cofactor<br />
for miRNA function?<br />
E. Glasmacher,<br />
K. P. Höfig, E. Kremmer,<br />
V. Heissmeyer<br />
Tumor Immunology<br />
Chair: J. Singer,<br />
T. Weichhart<br />
17. Higher avidity of<br />
TCR-gene-modified T<br />
cells by using parts of<br />
the murine constant TCR<br />
regions<br />
D. Sommermeyer,<br />
W. Uckert<br />
18. Reprogramming T<br />
cells to become MHC independent<br />
- electroporation<br />
of RNA encoding<br />
chimeric antigen receptors<br />
N. Schaft, T. Sch<strong>und</strong>er,<br />
C. Krug, S. Reuter,<br />
D. Kosmides, H. Abken,<br />
M. Kershaw,<br />
E. Kämpgen, G. Schuler,<br />
J. Dörrie<br />
19. Memory CD8+ T-cell<br />
mediated tumor rejection<br />
is impaired in NKG2Ddysfunctional<br />
mice<br />
M. C. Banerjea,<br />
D. Sigurdardottir,<br />
B. Pömmerl,<br />
H. Rammensee,<br />
A. Steinle<br />
20. Rejection of established<br />
cancer: Lack of<br />
IFN- , TNF- and Fas-ligand<br />
but not perforin by<br />
effector CD8+ T cells allows<br />
cancer to progress<br />
J. J. Listopad,<br />
G. Willimsky,<br />
B. Silkenstedt,<br />
T. Kammertöns,<br />
T. Blankenstein<br />
21. Defects of the antigen<br />
processing machinery<br />
leading to T cell<br />
resistance of melanoma<br />
cells<br />
M. Keller, F. Ebstein,<br />
A. Paschen, E. Bürger,<br />
D. Schadendorf,<br />
P. M. Kloetzel,<br />
U. Seifert<br />
22. Tumor-specific T<br />
helper cells regulate<br />
tumor dormancy or<br />
progress multistage carcinogenesis<br />
through T<br />
cell cytokines<br />
H. Braumueller,<br />
T. Wieder, N. Bauer,<br />
M. Rocken<br />
Immunomodulation<br />
Chair: K. Loser,<br />
W. Berger<br />
25. Regulation of homing<br />
receptor expression in<br />
CD4 + T cells<br />
B. A. Ratsch, C. Doebis,<br />
S. Jennrich, S. Floess,<br />
A. Hamann, U. Syrbe<br />
26. Regulated release<br />
and functional modulation<br />
of junctional adhesion<br />
molecule A by<br />
disintegrin metalloproteinases<br />
J. Pruessmeyer,<br />
R. Koenen, L. Fraemohs,<br />
O. Soehnlein, C. Weber,<br />
A. Ludwig<br />
27. Ontogeny of Langerhans<br />
cells in prenatal<br />
human skin<br />
C. Schuster, C. Vaculik,<br />
C. Fiala, W. Eppel,<br />
S. Meindl, M. Imhof,<br />
A. Elbe-Bürger<br />
28. Requirement of<br />
CCL17 for progression<br />
of atopic dermatitis and<br />
contact hypersensitivity<br />
in mice<br />
S. Stutte, N. Gerbitzki,<br />
I. Förster<br />
29. Acid sphingomyelinase<br />
is required for efficient<br />
phago-lysosomal<br />
fusion<br />
M. Schramm, U. Karow,<br />
A. Haas, M. Krönke,<br />
O. Utermöhlen<br />
30. Phenotypic and molecular<br />
analysis of an<br />
HLA Class II deficient<br />
patient reveals a homozygous<br />
nonsense<br />
mutation in the CIITA<br />
gene at amino acid position<br />
381<br />
K. G. Schmetterer,<br />
M. G. Seidel,<br />
U. Körmöczi,<br />
K. Schwarz, S. Matthes-<br />
Martin, P. Steinberger,<br />
W. F. Pickl<br />
Innate Immunity: Antigen-Presenting<br />
Cells<br />
Chair: N. Romani,<br />
H. Schild<br />
33. Targeting of<br />
Haemagglutinin antigen<br />
to C-type Lectins on<br />
human Dendritic Cells<br />
elicits different T cell responses<br />
in vitro<br />
G. F. Heidkamp,<br />
F. Nimmerjahn,<br />
A. Piperno, H. Zebroski,<br />
R. M. Steinman,<br />
M. C. Nussenzweig,<br />
D. Dudziak<br />
34. PPARgamma enhances<br />
uptake and<br />
cross-presentation of<br />
soluble antigen in dendritic<br />
cells<br />
S. Hucke, J. Floßdorf,<br />
I. Dani, D. Thimm,<br />
A. Kautz, C. Kurts,<br />
P. Knolle, L. Klotz,<br />
S. Burgdorf<br />
35. Genomic RNA of<br />
human rhinovirus - a<br />
”semi-danger-signal” for<br />
dendritic cells<br />
C. Schrauf,<br />
S. Kirchberger,<br />
O. Majdic, J. Seipelt,<br />
J. Stöckl<br />
36. Antagonism between<br />
GATA-1 and vitamin D3<br />
receptor in myelopoisis<br />
and dendritic cell subset<br />
differentiation<br />
S. Taschner-Mandl,<br />
F. Göbel, M. Kumerz,<br />
J. Jurkin, C. Vaculik,<br />
S. Richter, C.<br />
Bieglmayer,<br />
A. Elbe-Bürger,<br />
H. Strobl<br />
37. Function of hypoxiainducible<br />
factor (HIF)-1<br />
in dendritic cells<br />
T. Köhler,<br />
R. S. Johnson,<br />
H. Weighardt, I. Förster<br />
38. Distinct mechanism<br />
of antigen routing and<br />
cross-presentation in<br />
LSEC<br />
A. K. Schurich,<br />
J. Böttcher, S. Burgdorf,<br />
P. Penzler,<br />
S. Hegenbarth,<br />
D. Stabenow, A. Dolf,<br />
E. Endl, C. Kurts,<br />
P. A. Knolle
Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 (continued) 11<br />
Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
7. The effect of thymectomy<br />
in early childhood<br />
on the naive T cell compartment<br />
in later life<br />
M. Prelog, M. Keller,<br />
R. Geiger, A. Brandstaetter,<br />
R. Würzner,<br />
B. Grubeck-Loebenstein,<br />
L. B. Zimmerhackl<br />
8. Clonal evolution of the<br />
effector T cell repertoire<br />
D. Zehn, M. J. Bevan<br />
Time Lecture Hall 1<br />
12.15<br />
-<br />
13.45<br />
15. OSCAR, a key costimulation<br />
molecule for<br />
osteoclasts, is induced<br />
in patients with rheumatoid<br />
arthritis<br />
S. Herman, G. Krönke,<br />
R. Müller, J. Zwerina,<br />
K. Redlich, G. Schett<br />
16. Imaging immuneneuronal<br />
interactions in<br />
experimental auto -<br />
immune encephalo -<br />
myelitis using intravital<br />
two- photon microscopy<br />
V. Siffrin, J. Herz,<br />
T. Leuenberger,<br />
A. U. Brandt,<br />
H. Radbruch, R. Niesner,<br />
C. Infante-Duarte,<br />
F. Zipp<br />
Satellite Lunch Symposium - Roche<br />
B cell: Promising target in autoimmune diseases<br />
Chair: J. Smolen<br />
The biology of the B cell in autoimmune diseases<br />
A. Radbruch<br />
Clinical experiences with B cell therapies<br />
T. Dörner<br />
Safety: Experiences with Rituximab<br />
H-P. Brezinsek<br />
23. Identification of<br />
tumor antigens using antibodies<br />
induced by dendritic<br />
cell (DC) based<br />
vaccines<br />
J. Leitner, A. Stift,<br />
J. Friedl, R. Pfranger,<br />
P. Steinberger,<br />
K. Pfistershammer<br />
24. Serological relationship<br />
between cutaneous<br />
human papillomavirus<br />
types 5, 8 and 92<br />
A. Handisurya,<br />
C. Schellenbacher,<br />
R. Gambhira,<br />
S. Shafti-Keramat,<br />
O. Forsl<strong>und</strong>, M. Favre,<br />
R. Kirnbauer<br />
31. Different mechanisms<br />
of immunosuppression<br />
caused by<br />
Cyclosporine A (CsA)<br />
and FK506<br />
T. Giese, C. Sommerer,<br />
C. Jacobi, M. Zeier,<br />
S. Meuer<br />
32. Identification of three<br />
novel genes as<br />
biomarker for monitoring<br />
anti-TGFbeta therapy<br />
S. Classen, C. Muth,<br />
D. Eggle, M. Beyer,<br />
T. Zander,<br />
A. Staratschek-Jox,<br />
J. L. Schultze<br />
39. Skin dendritic cells<br />
present lipid antigens to<br />
natural killer T cells<br />
P. Stoitzner,<br />
I. F. Hermans,<br />
N. Romani
Scientific <strong>Programm</strong>e – Thursday, September 4, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
14.00<br />
-<br />
15.30<br />
T-Lymphocytes II<br />
Chair: M. Lohoff,<br />
A. Thiel<br />
40. Stability and flexibility<br />
of CD4 T cell differentiation<br />
programs in vitro<br />
and in vivo<br />
A. N. Hegazy,<br />
H. Hengartner,<br />
R. M. Zinkernagel,<br />
A. Radbruch,<br />
M. Löhning<br />
41. On the role of<br />
adipokines in Th2 lymphocyte<br />
polarization<br />
A. Batra, B. Okur, J.<br />
Ihbe, T. Stroh,<br />
R. Glauben, I. Fedke,<br />
M. Zeitz, B. Siegm<strong>und</strong><br />
42. In vivo generated<br />
Th17 cells have a stable<br />
memory for IL-17 expression<br />
M. H. Lexberg,<br />
I. Albrecht, A. Förster,<br />
A. Richter, A. Radbruch,<br />
H. D. Chang<br />
43. Role of HDAC in T<br />
helper cell development<br />
R. Glauben,<br />
E. Sonnenberg, I. Fedke,<br />
P. Mascagni, M. Zeitz,<br />
B. Siegm<strong>und</strong><br />
44. Human<br />
CD4 + CD25 + Foxp3 + regulatory<br />
T cells efficiently<br />
inhibit GvHD induction in<br />
a humanized mouse<br />
model<br />
C. Becker, J. Kubach,<br />
C. Taube, C. Becker,<br />
K. Michel, K. Reifenberg,<br />
H. Jonuleit<br />
45. Mathematical modeling<br />
of the diversity of the<br />
immunological synapse<br />
M. T. Figge,<br />
M. Meyer-Hermann<br />
Vaccines & Adjuvants<br />
Chair: B. Grubeck,<br />
S. Weiss<br />
48. Improvement of the<br />
Immunogenicity of a<br />
HIV-1 Clade C Candidate<br />
Vaccine increasing<br />
Gag, Pol, Nef and Env<br />
Specific T-Cell Responses<br />
J. Wild, J. Koestler,<br />
S. Bredl, K. Boeckl,<br />
R. Wagner<br />
49. Safety and immunogenicity<br />
in a phase I<br />
dose-escalation BPV-1<br />
VLP vaccine trial in<br />
horses<br />
R. Kirnbauer, S. Brandt,<br />
S. Shafti-Keramat,<br />
E. K. Hainisch<br />
50. Characterisation of<br />
effects on growth of<br />
Staphylococcus aureus<br />
mediated by specific<br />
IgGs<br />
B. Tosetti, E. Glowalla,<br />
M. Krönke, O. Krut<br />
51. Analysis of the<br />
mechanisms mediating<br />
dendritic cell-based vaccination<br />
against Leishmania<br />
major<br />
J. K. Schnitzer,<br />
C. Hambrecht,<br />
M. Fajardo-Moser,<br />
K. A. Remer,<br />
H. Moll<br />
52. Virus-like particles: A<br />
cell-free antigen-presenting<br />
platform modulating<br />
lymphocyte<br />
activation in vitro and in<br />
vivo<br />
H. J. Kueng, V. M. Leb,<br />
D. Haiderer, G. Raposo,<br />
C. Thery, S. V. Derdak,<br />
K. G. Schmetterer,<br />
A. Neunkirchner,<br />
C. Sillaber, B. Seed,<br />
W. F. Pickl<br />
53. Priming and boosting<br />
of melanA-specific T<br />
cells - in vitro studies on<br />
the importance of antigen-presentation<br />
density<br />
J. Dörrie, N. Schaft,<br />
V. Wellner, C. Wohn,<br />
T. Sch<strong>und</strong>er, I. Müller,<br />
E. Kämpgen, G. Schuler<br />
Signal Transduction<br />
Chair: T. Bürckstürmer,<br />
T. Stulnig<br />
56. Oxidation of cofilin<br />
mediates T cell hyporesponsiveness<br />
<strong>und</strong>er oxidative<br />
stress conditions<br />
M. Klemke, G. Wabnitz,<br />
F. Funke, B. Funk,<br />
H. Kirchgessner,<br />
Y. Samstag<br />
57. The orphan adapter<br />
protein SLY1 as a novel<br />
anti-apoptotic protein required<br />
for thymocyte development<br />
B. Reis, D. Finkenstaedt,<br />
D. K. Finlay,<br />
D. A. Cantrell, K. Pfeffer,<br />
S. Beer<br />
58. Micropatterning of<br />
CD4 in the live cell<br />
plasma membrane reveals<br />
novel binding<br />
mechanisms to Lck<br />
M. Schwarzenbacher,<br />
M. Kaltenbrunner,<br />
M. Brameshuber,<br />
C. Hesch, W. Paster,<br />
J. Weghuber, B. Heise,<br />
A. Sonnleitner, H. Stokkinger,<br />
G. J. Schütz<br />
59. Stat3 serine 727<br />
phosphorylation upon<br />
activated TLR binding<br />
promotes via<br />
MyD88/TRIF safekeeping<br />
of IL-1beta<br />
S. Dreher, F. Schmitz,<br />
R. Ferstl, S. Spiller,<br />
J. Marges, A. Heit, I. Förster,<br />
R. Lang, H. Wagner,<br />
C. J. Kirschning<br />
60. Carma1/Bcl10/Malt1<br />
Complexes Transmit<br />
ITAM-coupled NK Cell<br />
Receptor Signals for NF-<br />
B and MAPK Activation<br />
O. Groß, C. Grupp,<br />
C. Steinberg,<br />
S. Zimmermann,<br />
D. Strasser,<br />
N. Hannesschläger,<br />
W. Reindl, C. Peschel,<br />
A. Krug, J. Ruland<br />
61. Functional analysis<br />
of the riboflavin kinase<br />
and its role in TNF-induced<br />
signalling<br />
B. Yazdanpanah,<br />
C. Pongratz,<br />
K. Wiegmann,<br />
H. Kashkar, M. Krönke<br />
NK cells<br />
Chair: C. Watzl,<br />
M. Fischer<br />
64. The stress-inducible<br />
endogenous danger signals<br />
HSP70 and MICA<br />
synergistically activate<br />
the cytotoxic effector<br />
functions of human NK cells<br />
L. Elsner, P. F. Flügge,<br />
J. Lozano, V. Muppala,<br />
S. Y. Demiroglu,<br />
D. Malzahn, H. Bickeböller,<br />
G. Multhoff, L. Walter,<br />
R. Dressel<br />
65. Regulation of NK cell<br />
activity through extracellular<br />
HLA-B-Associated<br />
Transcript 3<br />
E. Pogge von Strandmann,<br />
V. Simhadri,<br />
K. S. Reiners,<br />
H. P. Hansen, A. Engert<br />
66. Natural killer cell’s<br />
activation by Immunomodulin<br />
for treatment<br />
strategy of<br />
recurrent genital herpes<br />
V. Garib, U. Djabborov,<br />
Y. Rasul-Zade<br />
67. Decision making in<br />
NK cells<br />
D. Urlaub, S. Mesecke,<br />
H. Busch, R. Eils,<br />
C. Watzl<br />
68. Natural killer cells are<br />
modulated in patients<br />
with neuroimmunologic<br />
disorders in response to<br />
treatment with intravenous<br />
immunoglobulin<br />
C. Jacobi, M. Claus,<br />
B. Wildemann,<br />
J. Römisch, C. Watzl,<br />
S. Meuer, T. Giese<br />
69. Myeloid-Derived<br />
“Suppressor” Cells express<br />
Rae-1 and activate<br />
NK cells<br />
A. Cerwenka,<br />
E. Schlecker, I. Galani,<br />
N. Nausch<br />
12<br />
Veterinary Immunology<br />
Chair: A. Saalmüller,<br />
M. Müller<br />
72. Charakterization of<br />
the chicken CD40-<br />
CD40L system unsing<br />
the RCAS retroviral gene<br />
transfer technology<br />
K. Schenk-Weibhauser,<br />
J. Young, B. Kaspers,<br />
S. Kothlow<br />
73. Analysis of potential<br />
antiviral MX activity in<br />
the chicken<br />
B. Schusser, N. Penski,<br />
A. Reuter, G. Kochs,<br />
P. Staeheli, B. Kaspers,<br />
S. Kothlow<br />
74. MHC typing in swine:<br />
SLA class I and class IIallele<br />
distribution in Austrian<br />
Large White,<br />
Landrace, and Pietrain<br />
breeding stocks<br />
S. E. Hammer,<br />
J. Deutsch,<br />
B. C. Rütgen, S. Groiß,<br />
W. Gerner,<br />
S. Müller, A. Saalmüller<br />
75. Porcine coccidiosis -<br />
adaptive immune response<br />
mechanisms<br />
against Isospora suis<br />
H. L. Worliczek,<br />
W. Gerner, A. Saalmüller,<br />
A. Joachim<br />
76. Potential diagnostic<br />
markers for subclinical<br />
endometritis in cows:<br />
TNF-alpha, IL-1 alpha,<br />
IL-1 beta, and IL-8<br />
C. Gabler, M. Drillich,<br />
C. Fischer, C. Holder,<br />
W. Heuwieser,<br />
R. Einspanier<br />
77. Toll-like receptor expression<br />
and bacterial<br />
strain dependent<br />
chemokine response in a<br />
primary bovine colonic<br />
epithelial cell culture<br />
model<br />
P. S. Bridger, M. Mohr,<br />
J. Fröhlich, H. Metcalfe,<br />
D. Werling, G. Baljer,<br />
C. Menge
Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 (continued)<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
15.30<br />
-<br />
16.30<br />
46. The role of the zinc<br />
finger protein MAZR in<br />
CD4/CD8 cell fate decisions<br />
during thymocyte<br />
development<br />
S. Sakaguchi, I. Bilic,<br />
M. Hombauer,<br />
A. Schebesta,<br />
W. Ellmeier<br />
47. 2D-DIGE analysis of<br />
enriched secretory lysosomes<br />
of human T and<br />
NK cells<br />
H. Schmidt, C. Gelhaus,<br />
M. Lettau,<br />
M. Nebendahl,<br />
M. Leippe, O. Janssen<br />
54. Propagation-deficient<br />
LCMV-derived vaccine<br />
vector efficiently<br />
targets dendritic cells to<br />
induce potent T and B<br />
cell responses against<br />
immunogens of choice<br />
L. Flatz, A. N. Hegazy,<br />
A. Verschoor,<br />
A. Bergthaler,<br />
M. Löhning,<br />
D. D. Pinschewer<br />
55. Vaccination with<br />
MHC class II-heterologous<br />
dendritic cells induces<br />
protective<br />
immunity against Leishmania<br />
major<br />
K. A. Remer, H. Moll<br />
62. The DEAD-box helicase<br />
DDX3X is a critical<br />
component of the TANKbinding<br />
kinase 1-dependent<br />
innate immune<br />
response<br />
D. Soulat,<br />
T. Buerckstuemmer,<br />
S. Westermayer,<br />
A. Goncalves, A. Bauch,<br />
A. Stefanovic,<br />
O. Hantschel,<br />
K. L. Bennett, T. Decker,<br />
G. Superti-Furga<br />
63. Post-transcriptional<br />
regulation of FasL expression:<br />
Molecular insights<br />
into storage,<br />
activation-induced mobilization<br />
and shedding<br />
of a prototypic death<br />
factor<br />
M. Lettau, O. Janssen<br />
Coffee Break / Poster Viewing / Exhibition<br />
70. Characterization of a<br />
novel, RORgt-expressing<br />
mucosal NK cell population<br />
S. L. Sanos, A. Mortha,<br />
V. Bui, K. Oberle,<br />
A. Diefenbach<br />
71. Specificity of interaction<br />
between killer cell<br />
immunoglobulin-like receptors<br />
(KIR) and MHC<br />
class I molecules of the<br />
rhesus macaque<br />
(Macaca mulatta)<br />
P. Kruse, C. Rosner,<br />
M. Hermes, L. Walter<br />
13<br />
78. Analysis of CD28 in<br />
horses and application<br />
of a polyclonal Ab to induce<br />
co-stimulation<br />
S. Ibrahim,<br />
E. Abd El-Gawad,<br />
F. Steinbach<br />
79. Species-specific<br />
generation of immune<br />
regulatory molecules by<br />
host pathogen coevolution<br />
R. Kammerer, T. Popp,<br />
S. Haertle, B. B. Singer,<br />
E. Travanty, Z. Qian,<br />
K. V. Holmes,<br />
W. Zimmermann
Scientific <strong>Programm</strong>e – Thursday, September 4, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />
16.45<br />
-<br />
18.00<br />
Parallel Symposium 2:<br />
Vaccination<br />
Chair: M. Müller, H.J. Schild<br />
Delineation of plasmablast characteristics<br />
generated in steady-state and in systemic<br />
immune responses<br />
H. Mei<br />
Towards a coronavirus- based multigene<br />
vaccine platform<br />
B. Ludewig<br />
Modulating Vaccine Responses with<br />
Innate Immunity<br />
B. Pulendran<br />
19.00 Welcome Reception at the Vienna City Hall<br />
Parallel Symposium 2:<br />
In Vivo Imaging<br />
Chair: C. Scheinecker, C. Berek<br />
The In Situ Dynamics of Innate and Adaptive<br />
Immune Cell Behaviour Revealed By<br />
Intravital Multiphotometry Microscopy<br />
R. Germain<br />
In vivo imaging of Germinal Center B Cells<br />
A.E. Hauser<br />
Non-invasive imaging of inflammation -<br />
the quest for specificity<br />
A. W<strong>und</strong>er<br />
NUDIST COLONIES.<br />
CD-1-nude • NMRI-nude • BALB/c-nude<br />
We’ve improved the availability of our nude mouse strains.<br />
For more information, please contact us at:<br />
Call: +49 (0) 9761/ 406-0 • +31 (0) 43 40 77 310<br />
E-mail: dbestell@crl.com • nlbestel@crl.com<br />
scand@criver.de<br />
Parallel Symposium 2:<br />
Immunomodulation<br />
Chair: W. Ellmeier, E. Schmitt<br />
Probing Dendritic cell In vivo Functions<br />
S. Jung<br />
Tec kinases in T cell activation and<br />
function<br />
L. Berg<br />
14<br />
Inducible Foxp3-dependent or -independent<br />
human CD4+ regulatory T Cells.<br />
R. Bacchetta
Scientific <strong>Programm</strong>e – Friday, September 5, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />
08.15<br />
-<br />
09.30<br />
09.30<br />
-<br />
10.30<br />
Parallel Symposium 1:<br />
Innate Immunity: Regulation<br />
Chair: M. Säemann, W. Solbach<br />
Innate resistance, inflammation, and<br />
cancer<br />
G. Trinchieri<br />
Interferon regulatory factors and innate<br />
immunity in early life<br />
M. Goldman<br />
The mammalian target of rapamycin and<br />
innate immunity<br />
T. Weichhart<br />
Parallel Symposium 1:<br />
Mucosal Inflammation<br />
Chair: B. Bohle, D. Männel<br />
Role of epithelial barrier function in allergy<br />
P. Brandtzaeg<br />
A prominent role for mucosal cystine/cysteine<br />
metabolism in intestinal immunoregulation<br />
S. Meuer<br />
Tumor Necrosis Factor and the consequences<br />
of its ablation in vivo<br />
S. Nedospasov<br />
Coffee Break / Poster Viewing / Exhibition<br />
Parallel Symposium 1:<br />
Transplantation<br />
Chair: T. Wekerle, R. Schmidt<br />
Antibody-mediated transplant rejection<br />
G. Böhmig<br />
15<br />
Immune monitoring and therapy in transplantation<br />
- from bench-to -bedside<br />
H.D. Volk<br />
Tolerance through mixed chimerism: how<br />
close to clinical application is it?<br />
T. Wekerle
Scientific <strong>Programm</strong>e – Friday, September 5, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
10.30<br />
-<br />
12.15<br />
Allergy I<br />
Chair: H. Renz,<br />
F. Horak<br />
80. Tracing antigen signatures<br />
in the human<br />
IgE repertoire<br />
K. Marth,<br />
M. Novatchkova,<br />
M. Focke-Tejkl,<br />
S. Jenisch, S. Jäger,<br />
D. Kabelitz, R. Valenta<br />
81. Stable dust challenge<br />
inhibits allergic airway<br />
reactivity through<br />
TLRs 2, 3, 4, 7, 9 and/or<br />
other PRRs/TLRs<br />
R. Ferstl, S. Spiller,<br />
S. Dreher, H. Garn,<br />
H. Fehrenbach,<br />
E. Von Mutius, H. Renz,<br />
H. Wagner,<br />
C. J. Kirschning<br />
82. Composition of B<br />
cell receptor classic antigen-binding<br />
site regulates<br />
allergic airway<br />
inflammation in a murine<br />
model of experimental<br />
asthma<br />
S. Kerzel, J. Wagner,<br />
T. Rogosch, A. Yildirim,<br />
H. Fehrenbach, H. Garn,<br />
R. F. Maier,<br />
H. W. Schroeder Jr.,<br />
M. Zemlin<br />
83. High expression of<br />
inflammatory cytokines,<br />
chemokines and their receptors<br />
in lungs of mice<br />
during allergic asthma<br />
remission <strong>und</strong>erlies the<br />
persistence of chronic<br />
lung inflammation<br />
R. Bankoti,<br />
L. El-Housseiny,<br />
G. Dekan, O. Hoffmann,<br />
G. Stingl, M. M. Epstein<br />
84. Antigen -specific immunotherapy<br />
inhibited<br />
Th2 via GATA-3 and<br />
Th17 cells in an allergic<br />
asthma model.<br />
N. Zhivkova, R. Karwot,<br />
J. H. Maxeiner,<br />
P. Scholtes, K. Soo,<br />
S. Finotto<br />
85. Selective depletion<br />
of Foxp3+ cells in<br />
DEREG mice allows<br />
functional analysis of<br />
regulatory T cells during<br />
experimental allergic airway<br />
inflammation<br />
A. Hartl, K. Lahl,<br />
H. Hamad, A. Ö. Yildirim,<br />
H. Fehrenbach, R. Teich,<br />
H. Garn, H. Renz,<br />
B. Lambrecht,<br />
T. Sparwasser<br />
Regulatory Lymphocytes<br />
I<br />
Chair: L. Klein,<br />
T. Wekerle<br />
88. Analyses of a novel<br />
regulatory T cell subset<br />
in patients with Systemic<br />
Lupus Erythematosus<br />
(SLE)<br />
M. Bonelli,<br />
A. Savitskaya, E. Feierl,<br />
S. S. Smolen,<br />
C. Scheinecker<br />
89. CD4 + CD25 high regulatory<br />
T cells suppress T<br />
helper 1 but not T helper<br />
2 cytokines<br />
T. Bollinger,<br />
A. Bollinger, W. Solbach<br />
90. Induction of CD25 -<br />
Foxp3 - regulatory T cells<br />
by chronic antigen stimulation<br />
in vivo<br />
W. Hansen,<br />
A. M. Westendorf,<br />
J. Buer<br />
91. Transfer of in vitro<br />
expanded human<br />
CD45RA+CD4+CD25hig<br />
h regulatory T cells inhibits<br />
early expansion of<br />
conventional T cells in<br />
immunodeficient Rag2-/c-/-<br />
mice<br />
T. J. Boeld, J. Albrecht,<br />
K. Doser, R. Eder, J. Stahl,<br />
E. Typlt, E. Obermann,<br />
R. Andreesen,<br />
P. Hoffmann, M. Edinger<br />
92. Long-term vaccination<br />
efficiency is independent<br />
of regulatory T<br />
cells<br />
G. Gasteiger,<br />
W. Kastenmuller,<br />
L. Stross, D. H. Busch,<br />
T. Sparwasser, I. Drexler<br />
93. Retrovirally transduced,<br />
antigen-specific<br />
T cells for therapy of<br />
type 1 diabetes<br />
N. Mpofu, N. Saal,<br />
M. Hardtke-Wolenski,<br />
M. P. Manns, E. Jaeckel<br />
Alloimmunity & Tolerance<br />
Chair: B. Arnold,<br />
H. Ankersmit<br />
96. Role of IL-2 in induction<br />
of CD8 T cell tolerance<br />
by LSEC<br />
A. K. Schurich, M. Berg,<br />
A. Limmer, H. J. Schild,<br />
L. Diehl, P. A. Knolle<br />
97. Proliferation of CD8positive<br />
T cells in the Lumina<br />
of Rat Renal<br />
Allograft Blood Vessels<br />
V. Grau, G. Fuchs-Moll,<br />
W. Padberg<br />
98. Dickkopf 3, a novel<br />
modulator of T cell responses<br />
M. Papatriantafyllou,<br />
G. Moldenhauer,<br />
H. J. Gröne, C. Niehrs,<br />
G. J. Hämmerling,<br />
T. Oelert, B. Arnold<br />
99. Toag-1 enables prediction<br />
of CMV mediated<br />
transplant tolerance abrogation<br />
W. Gong, M. Klöpfel,<br />
K. Vogt, S. Haase,<br />
A. Reutzel-Selke,<br />
H. Volk, A. Pascher,<br />
B. Sawitzki<br />
100. Mutated CYLD affects<br />
the functional state<br />
of dendritic cells<br />
M. Bros, N. Wiechmann,<br />
V. Besche,<br />
N. Hövelmeyer,<br />
S. Reissig,<br />
S. Grabbe, A. Waisman,<br />
A. B. Reske-Kunz<br />
101. Enhanced nuclear<br />
export of NFATc1 and<br />
impaired translocation of<br />
NFATc2 is observed in<br />
anergic iTreg generated<br />
by tolerogenic DC<br />
H. S. Adler, R. Orth,<br />
K. Streck, E. Graulich,<br />
K. Steinbrink<br />
Pattern Recognition<br />
Receptors & Myeloid<br />
Cells<br />
Chair: S. Bauer,<br />
C. Bogdan<br />
104. Influence of viral infection<br />
on recognition of<br />
self RNA<br />
T. von Thülen, M. Nain,<br />
S. Bauer<br />
105. TLR7-dependent<br />
recognition of transfer<br />
RNA<br />
Y. Zhao, A. Kaufmann,<br />
K. Steinbach, S. Bauer<br />
106. Intrabody mediated<br />
retention of TLR2 and<br />
TLR9 in the ER to inhibit<br />
chronic inflammation<br />
T. Böldicke, S. Dreher,<br />
S. Somplatzki,<br />
L. Grosse-Hovest,<br />
B. Maaß,<br />
W. Lindenmaier,<br />
H. Wagner,<br />
C. Kirschning<br />
107. Analysis of Toll-like<br />
receptor 7 and Toll-like<br />
receptor 9 chimeric molecules<br />
J. Willemsen, P. Yu,<br />
S. Bauer<br />
108. The divergent role<br />
of the mammalian target<br />
of rapamycin (mTOR) in<br />
dendritic cells subtypes<br />
M. Haidinger,<br />
T. Weichhart,<br />
M. Poglitsch, M. Hecking,<br />
M. Zeyda, R. Geyeregger,<br />
J. Werzowa, W. H. Hörl,<br />
M. D. Säemann<br />
109. Mammalian target<br />
of rapamycin (mTOR) orchestrates<br />
the defense<br />
program of innate immune<br />
cells<br />
F. Schmitz, A. Heit,<br />
S. Dreher, K. Tittel,<br />
J. Mages, T. Haas,<br />
A. Krug, K. Janssen,<br />
C. V. Kirschning,<br />
H. Wagner<br />
Innate Immunity:<br />
Regulation<br />
Chair: M. Zeyda,<br />
K. Pfeffer<br />
16<br />
112. Suppression of<br />
adaptive immune responses<br />
by Toll-like receptor<br />
ligands<br />
B. Schumak, M. Brock,<br />
F. Jüngerkes,<br />
G. Hartmann, T. Tüting,<br />
P. Knolle, R. Zawatzky,<br />
S. Bauer, A. Limmer<br />
113. The cytoplasmic tail<br />
of CD45 is released from<br />
activated phagocytes<br />
and can act as an inhibitory<br />
messenger for<br />
T cells<br />
S. Kirchberger,<br />
O. Majdic, S. Blüml,<br />
C. Schrauf, J. Leitner,<br />
C. Gerner, W. Paster,<br />
N. G<strong>und</strong>acker, M. Sibilia,<br />
J. Stöckl<br />
114. Molecular mechanisms<br />
of Staphylococcus<br />
aureus-induced autophagy<br />
K. Sabel, D. Grumme,<br />
S. A. Leggio,<br />
A. Schnaith, M. Krönke,<br />
O. Krut<br />
115. 12/15-lipoxygenase<br />
is involved in the limitation<br />
of inflammation and<br />
tissue damage in murine<br />
arthritis<br />
G. Krönke,<br />
J. Katzenbeisser,<br />
S. Uderhardt, W. Baum,<br />
R. Axmann, J. Zwerina,<br />
G. Schett<br />
116. Promoter methylation<br />
status is changed<br />
with altered DEFB1 gene<br />
expression in COPD<br />
E. Andresen,<br />
J. Bullwinkel, C. Lange,<br />
H. Heine<br />
117. Macrophage phosphoproteome<br />
dynamics<br />
after LPS-stimulation<br />
and its shaping by the<br />
MAPK-Phosphatase<br />
DUSP1: a SILAC-based<br />
approach<br />
G. Weintz, J. Olsen,<br />
J. Mages, M. Mann,<br />
R. Lang
Scientific <strong>Programm</strong>e – Friday, September 5, 2008 (continued)<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
86. Molecular and functional<br />
analysis of the<br />
antigen receptor of Bet v<br />
1-specific helper T lymphocytes<br />
A. Neunkirchner,<br />
V. M. Leb,<br />
K. G. Schmetterer,<br />
H. J. Kueng, D. Haiderer,<br />
S. Mutschlechner,<br />
B. Bohle, W. F. Pickl<br />
87. Cloning, expression<br />
and mapping of allergenic<br />
determinants of<br />
alphaS1-casein, a major<br />
cow’s milk allergen<br />
U. Schulmeister,<br />
H. Hochwallner,<br />
I. Swoboda, M. Focke-<br />
Tejkl, M. Nystrand,<br />
A. Harlin, J. Thalhamer,<br />
S. Scheiblhofer, W. Keller,<br />
B. Niggemann, S. Quirce,<br />
C. Ebner, A. Mari,<br />
G. Pauli, B. Geller,<br />
U. Herz, R. Valenta,<br />
S. Spitzauer<br />
Time Lecture Hall 2<br />
12.15<br />
-<br />
13.45<br />
94. BAC-transgenic mice<br />
for depletion of Foxp3 +<br />
regulatory T cells:<br />
Homeostatic expansion<br />
of Tregs<br />
J. Suffner,<br />
K. Hochweller, N. Garbi,<br />
G. Hämmerling<br />
95. Lack of Foxp3 Treglinage<br />
marker expression<br />
in mouse epithelial cells<br />
C. T. Mayer, K. Lahl,<br />
C. Loddenkemper,<br />
T. D. Sparwasser<br />
102. Allogeneic disparities<br />
in the surface molecule<br />
immunoglobulin-like<br />
transcript 5 (ILT-5) induce<br />
potent antibody responses<br />
in stem cell<br />
transplanted patients<br />
K. Pfistershammer , ,<br />
A. Lawitschka, J. Leitner,<br />
C. Klauser, R. Weigl,<br />
G. Böhmig, G. F. Fischer,<br />
M. Heemskerk,<br />
O. Majdic, W. F. Pickl,<br />
H. Greinix, P. Steinberger<br />
103. Dendritic cell-activated,<br />
endothelial cellspecific<br />
CTL recognizing<br />
a minor histocompatibility<br />
antigen rapidly induce<br />
transplant vasculopathy<br />
B. B. Bolinger,<br />
D. Engeler, P. Krebs,<br />
S. Miller, B. Ludewig,<br />
M. Hoffmann, P. Clavien,<br />
Y. Tian<br />
110. Hsp60 modulates<br />
neutrophil functions<br />
A. Osterloh,<br />
M. Piedavent,<br />
F. Geisinger,<br />
B. Fleischer, N. Brattig,<br />
M. Breloer<br />
111. Spatial separation<br />
of cross-presentation<br />
and endogenous antigen<br />
presentation<br />
S. Burgdorf, C. Schölz,<br />
A. Kautz, R. Tampé,<br />
C. Kurts<br />
Satellite Lunch Symposium - Octapharma<br />
Immune modulation with intravenous immunoglobulin: the established and the advances<br />
Chair: S. Meuer<br />
17<br />
118. Prophylactic blockade<br />
of TLR4 or therapeutic<br />
blockade of both<br />
TLR2 and TLR4 protects<br />
mice from Gram-negative<br />
infection and subsequent<br />
antibiotic therapy<br />
induced fatal septic<br />
shock<br />
C. J. Kirschning,<br />
G. Elson, R. Ferstl,<br />
S. Dreher, T. Müller,<br />
M. Freudenberg,<br />
B. Daubeuf, H. Wagner,<br />
S. Spiller<br />
119. Biological characterization<br />
of mouse beta<br />
defensin 14 - an orthologue<br />
of human beta<br />
defensin 3<br />
J. Röhrl, T. Hehlgans<br />
Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and autoimmune diseases<br />
P. Imbach<br />
Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacy<br />
F. Nimmerjahn<br />
Basic research in human immunology creates new therapeutic options<br />
S. Meuer<br />
Discussion and wrap-up<br />
Time Lecture Hall 1<br />
13.00<br />
-<br />
13.45<br />
Drittmittelförderung der DFG: Kriterien <strong>für</strong> eine erfolgreiche Antragstellung<br />
Chair: Y. Samstag<br />
A. Strecker
Scientific <strong>Programm</strong>e – Friday, September 5, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
14.00<br />
-<br />
15.30<br />
Infection I<br />
Chair: F. Schmitz,<br />
S. Ehlers<br />
120. Restricted B cell receptor<br />
diversity converts<br />
acute into chronic viral<br />
infection<br />
A. Bergthaler, L. Flatz,<br />
A. Verschoor,<br />
A. N. Hegazy,<br />
E. Horvath, M. Holdener,<br />
K. Fink, B. Odermatt,<br />
D. D. Pinschewer<br />
121. Interleukin 18 is essential<br />
for protective immunity<br />
against M.<br />
tuberculosis.<br />
B. Schneider,<br />
D. Korbel, K. Hagens,<br />
M. Koch,<br />
S. H. Kaufmann,<br />
H. Mittruecker,<br />
U. E. Schaible<br />
122. Wnt/Frizzled signaling<br />
in infectious diseases:<br />
Deciphering the<br />
role of FZD1 in mycobacterial<br />
infections<br />
N. Reiling,<br />
T. Endermann, S. Ehlers,<br />
J. Neumann<br />
123. Cavity formation in<br />
tuberculosis is mediated<br />
by interleukin-4 receptor-alpha-dependent<br />
mechanisms<br />
L. Heitmann,<br />
T. Schreiber, T. Thye,<br />
A. N. McKenzie,<br />
A. Cutler, F. Brombacher,<br />
R. D. Horstmann,<br />
C. G. Meyer, S. Ehlers,<br />
C. Hoelscher<br />
124. Immunological inhibition<br />
of gC1qR/p33, a<br />
receptor for C1q, decreases<br />
adherence of<br />
Staphylococcus aureus<br />
to microvascular endothelium<br />
S. Sethi, M. W. Laschke,<br />
J. Roller, L. von Mueller,<br />
E. Peerschke,<br />
B. Ghebrehiwet, I. Bajric,<br />
M. D. Menger,<br />
M. Herrmann<br />
125. The fibrin-derived<br />
peptide B 15-42 (FX06)<br />
for treatment of capillary<br />
leak<br />
M. Gröger, W. Pasteiner,<br />
G. Ignatyev, U. Matt,<br />
S. Knapp, P. Friedl,<br />
D. Zinkl, K. Zacharowski,<br />
R. Hofer-Warbinek,<br />
P. Petzelbauer,<br />
S. Reingruber<br />
Allergy II<br />
Chair: B. Linhart,<br />
G. Stary<br />
128. HLA-classII/peptide-TCR<br />
interactions of<br />
the single immunodominant<br />
T cell epitope of Art<br />
v 1, the major mugwort<br />
pollen allergen<br />
B. Jahn-Schmid,<br />
B. Maillere, V. Leb,<br />
W. Pickl, G. Gadermaier,<br />
F. Ferreira, B. Bohle<br />
129. Proteomic analysis<br />
and mass-spectrometric<br />
identification of differentially<br />
regulated proteins<br />
in primary human keratinocytes<br />
by allergens<br />
S. Ohnesorge, L. Dietz,<br />
P. Pankert,<br />
M. Schnoelzer,<br />
H. Thierse<br />
130. Immunosuppression<br />
and allergy in organ<br />
transplant recipients: evidence<br />
for insufficient<br />
control of allergen specific<br />
responses<br />
T. Eiwegger, S. Gruber,<br />
C. Geiger, E. Dehlink,<br />
T. Frischer, P. Jaksch,<br />
W. Klepetko,<br />
Z. Szépfalusi<br />
131. Long-term tolerance<br />
in IgE-mediated allergy<br />
through molecular<br />
hematopoietic<br />
chimerism in a murine<br />
model<br />
U. Baranyi, B. Linhart,<br />
N. Pilat, M. Gattringer,<br />
C. Klaus, E. Schwaiger,<br />
F. Muehlbacher,<br />
J. Iacomini, R. Valenta,<br />
T. Wekerle<br />
132. Generation of an<br />
IgE knock-in mouse and<br />
its use in systemic anaphylaxis<br />
in vivo<br />
P. Yu, W. Lübben,<br />
S. Bauer<br />
133. Murine plasma and<br />
non-plasma B cells express<br />
different IgE repertoires<br />
T. Rogosch, S. Kerzel,<br />
L. Sikula, R. Maier,<br />
M. Zemlin<br />
Regulatory Lymphocytes<br />
II<br />
Chair: A. Rosenkranz,<br />
H. Schulze-Koops<br />
136. Generation of induced<br />
CD8+Foxp3+ regulatory<br />
T cells in vitro<br />
C. Mayer, K. Lahl,<br />
D. Dittlein, V. Wenzel,<br />
O. Gassner, J. Stephani,<br />
C. Loddenkemper,<br />
T. Sparwasser<br />
137. CD8 + CD38 + T-cells:<br />
A competent regulatory<br />
T-cell population<br />
A. Bollinger,<br />
H. Fehrenbach,<br />
T. Bollinger, T. Bollinger,<br />
Z. Orinska,<br />
S. Bulfone-Paus<br />
138. Tolerogenic potential<br />
of lentivirally transduced<br />
murine DC<br />
overexpressing antiinflammatory<br />
molecules<br />
V. Besche,<br />
N. Wiechmann,<br />
S. Trojandt, S. Grabbe,<br />
A. B. Reske-Kunz,<br />
M. Bros<br />
139. IL-27 inhibits the<br />
development of regulatory<br />
T cells via STAT3<br />
M. Huber, V. Steinwald,<br />
A. Guralnik, A. Brüstle,<br />
P. Kleemann,<br />
C. Rosenplänter,<br />
T. Decker, M. Lohoff<br />
140. Development of<br />
“would-be” regulatory T<br />
cells and defective control<br />
of Th2-cytokine production<br />
in natural scurfy<br />
mutant mice<br />
K. I. Lahl, C. T. Mayer,<br />
J. Huehn, C. Loddenkemper,<br />
G. Eberl,<br />
J. Buer, T. Sparwasser<br />
141. TLR2 ligands act<br />
directly on Treg to abrogate<br />
suppression of<br />
CD4+CD25- T cells<br />
H. Oberg, M. Juricke,<br />
S. Ussat, H. Ly,<br />
D. Kabelitz, D. Wesch<br />
Mucosal Immunity<br />
Chair: R. Förster,<br />
M. Pasparakis<br />
144. Role of the transcription<br />
factor PU.1 in<br />
human lamina propria<br />
macrophages<br />
F. A. Lasitschka,<br />
A. Heidtmann, T. Giese,<br />
G. Wabnitz,<br />
A. Schrödter, J. Winter,<br />
A. Ulrich, S. C. Meuer,<br />
J. Schröder-Braunstein<br />
145. Role of eosinophils<br />
in TGF-beta expression<br />
in human intestine<br />
F. Ulmer, S. C. Bischoff,<br />
A. Lorentz<br />
146. CD4 + Foxp3 + regulatory<br />
T cell expansion<br />
induced by antigen-driven<br />
interaction with intestinal<br />
epithelial cells<br />
independent of local<br />
dendritic cells<br />
A. M. Westendorf,<br />
D. Fleissner, S. Jung,<br />
A. D. Gruber, W. Hansen,<br />
J. Buer<br />
147. Split tolerance after<br />
oral vaccination of mice<br />
with recombinant Escherichia<br />
coli Nissle<br />
1917 expressing fimbrial<br />
adhesin K88<br />
K. A. Remer,<br />
M. Bartrow, H. Moll,<br />
T. A. Oelschläger<br />
148. The role of IL-23/IL-<br />
17 in Toxoplasma gondii<br />
induced small intestinal<br />
immunopatology<br />
M. L. Munoz-Roldan,<br />
D. Struck, M. Heimesaat,<br />
C. Hoelscher, U. Mueller,<br />
Y. Iwakura, N. Ghilardi,<br />
O. Liesenfeld<br />
149. The mesenteric<br />
lymph node regulates<br />
the amplitude of IgA<br />
secretion in the drained<br />
area: potential role of the<br />
spleen in the immune<br />
response against orally<br />
applied cholera toxin<br />
A. Hahn, N. Thiessen,<br />
R. Pabst, M. Ahrendt,<br />
U. Bode<br />
B-Lymphocytes<br />
Chair: V. Sexl,<br />
T. Winkler<br />
18<br />
152. Swiprosin 1 - positive<br />
regulator of BCR induced<br />
calcium flux<br />
C. Kroczek, C. Lang,<br />
A. Avramidou,<br />
L. Nitschke, A. Elter,<br />
H. M. Jäck, D. Mielenz<br />
153. Engagement of<br />
CD83 on B cells augments<br />
IgG1 response in<br />
vivo<br />
B. Kretschmer,<br />
K. Lüthje,<br />
S. Schneider,<br />
B. Fleischer, M. Breloer<br />
154. The analysis of intravital<br />
two-photon imaging<br />
of germinal<br />
centres implies a novel<br />
lymphocyte migration<br />
and affinity maturation<br />
model<br />
M. Meyer-Hermann,<br />
M. Figge<br />
155. Proapoptotic BH3only<br />
proteins Bim and<br />
Puma are essential for<br />
apoptosis of germinal<br />
center-derived memory<br />
B cells and antibodyforming<br />
cells<br />
S. Fischer , , D. Tarlinton,<br />
A. Strasser<br />
156. Identification of a<br />
chemokine receptor profile<br />
characteristic for mediastinal<br />
large B-cell<br />
lymphoma<br />
U. E. Höpken,<br />
I. Anagnostopoulos,<br />
M. Broemer,<br />
C. Scheidereit,<br />
K. Joehrens, M. Hübler,<br />
H. Stein, M. Lipp,<br />
B. Dörken, A. Rehm<br />
157. The adapter protein<br />
SLy2 represents a newly<br />
identified regulator of cytoskeletalrearrangements<br />
M. L. von Holleben
Scientific <strong>Programm</strong>e – Friday, September 5, 2008 (continued)<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
15.30<br />
-<br />
16.30<br />
Time Lecture Hall 2<br />
18.00<br />
-<br />
19.30<br />
175. Immunopathological<br />
basis of lymphocytic<br />
choriomeningitis virusinduced<br />
chorioretinitis<br />
and keratitis<br />
M. Zinkernagel, P. Krebs,<br />
B. Bolinger, S. Miller,<br />
B. Ludewig<br />
127. CD8 T cell-mediated<br />
immune responses<br />
against cross-presenting<br />
liver sinusoidal endothelial<br />
cells leads to hepatitis<br />
D. Stabenow,<br />
K. Gärtner, M. Svorcova,<br />
M. Odenthal, H. Dienes,<br />
U. Protzer, P. A. Knolle<br />
General Assembly DGfI<br />
Chair: S. Meuer<br />
134. Induced ablation of<br />
mast cells in adult mice:<br />
Slow recovery of mast<br />
cell populations in the<br />
tissues.<br />
J. Scholten,<br />
A. Gerbaulet, B. Hiller,<br />
W. Muller, T. Krieg,<br />
T. Buch, A. Waisman,<br />
K. Hartmann, A. Roers<br />
135. Timothy grass<br />
pollen major allergen Phl<br />
p 1 - a protease?<br />
K. Röschmann,<br />
P. König, A. J. Ulmer,<br />
A. Petersen<br />
142. Influence of<br />
CD4+CD25+ regulatory<br />
T cells on the<br />
transendothelial migration<br />
of CD4+CD25- T<br />
cells<br />
T. Bedke, M. Kretz,<br />
K. Mahnke, A. H. Enk<br />
143. Expansion of immune-suppressive<br />
V 9V 2 T cells as a novel<br />
regulatory mechanism of<br />
IL-12 secreting dendritic<br />
cells<br />
M. W. Traxlmayr,<br />
A. M. Dohnal, D. Wesch,<br />
D. Kabelitz, T. Felzmann<br />
Coffee Break / Poster Viewing / Exhibition<br />
150. The role of CXCR5<br />
in antigen-independent<br />
development and antigen-dependentmaturation<br />
of nose-associated<br />
lymphoid tissue (NALT)<br />
J. Krege, S. Seth,<br />
S. Hardtke, A. Marques<br />
Davalos-Misslitz,<br />
R. Förster<br />
151. T cell-specific deletion<br />
of gp130 renders<br />
the highly susceptible Interleukin-10<br />
deficient<br />
mouse mutant resistant<br />
to intestinal nematode<br />
infection<br />
N. Fasnacht,<br />
M. C. Greweling,<br />
M. Bollati-Fogolin , ,<br />
A. Schippers , , W. Müller ,<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />
16.45<br />
-<br />
18.00<br />
Parallel Symposium 2:<br />
Infection<br />
Chair: S. Knapp, I. Förster<br />
Origin of CD8+ effector and memory T cell<br />
subsets<br />
D.H. Busch<br />
Mutual host pathogen reactions in tuberculosis<br />
U. Schaible<br />
Innate immune response to pneumococcal<br />
pneumonia<br />
S. Knapp<br />
Parallel Symposium 2:<br />
Adaptive Immunity: Regulation<br />
Chair: H. Stockinger, L. Klein<br />
Innate and adaptive IL-17 in the control of<br />
immune responses<br />
B. Stockinger<br />
Autoregulatory circuits in inflammatory<br />
T cell responses<br />
A. Scheffold<br />
Innate Immunity in regulation of antibody<br />
mediated inflammation<br />
R.E. Schmidt<br />
19.30 Departure with buses to the Viennese “Heuriger” Fuhrgassl-Huber<br />
19<br />
158. Antigen receptor tail<br />
clue of class-switched<br />
memory B cells<br />
N. Engels, C. Heemann,<br />
L. König, T. Tsubata,<br />
S. Griep, V. Schrader,<br />
J. Wienands<br />
159. Role of basophils in<br />
immunological memory<br />
responses<br />
A. J. Denzel, U. Maus,<br />
M. Rodriguez Gomez,<br />
M. Niedermeier, Y. Talke,<br />
N. Göbel, M. Mack<br />
Parallel Symposium 2:<br />
Adaptive Immunity: B-Cells<br />
Chair: G. Zlabinger, H-M. Jäck<br />
Transcriptional control of B cell development<br />
M. Busslinger<br />
Memory B cell sub-populations<br />
J.C. Weill<br />
Plasma cell memory<br />
A. Radbruch
Scientific <strong>Programm</strong>e – Saturday, September 6, 2008<br />
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />
08.45<br />
-<br />
10.00<br />
10.00<br />
-<br />
10.30<br />
Your Power for Health<br />
Parallel Symposium 1:<br />
Autoimmunity<br />
Chair: J. Smolen, H. Schulze-Koops<br />
The life history of an autoimmune driver<br />
clone<br />
E. Sercarz<br />
Immunopathogenesis of rheumatoid arthritis:<br />
induction of arthritogenic autoimmune<br />
reactions by proinflammatory stimuli<br />
G. Steiner<br />
Modeling multiple sclerosis: autoimmune<br />
T and B cells in the pathogenesis of the<br />
brain inflammatory disease<br />
H. Wekerle<br />
Moderne Antikörper-Analyse<br />
Immunologische Produkte<br />
von Greiner Bio-One<br />
Gleichbleibende <strong>und</strong> reproduzierbare<br />
Bindung von Proteinen<br />
Geeignet <strong>für</strong> Transmissions-, Fluoreszenz-<br />
<strong>und</strong> Lumineszenzmessungen<br />
Konstante, einheitliche Bindungseigenschaften<br />
Vielfältiges Spektrum an Microplatten<br />
<strong>und</strong> Streifen-Platten<br />
Kompatibel mit automatisierten Systemen<br />
Parallel Symposium 1:<br />
Inflammation<br />
Chair: J. Stöckl, K. Pfeffer<br />
Mechanisms of inflammatory bone<br />
destruction<br />
K. Redlich<br />
Novel cytokines in inflammatory diseases<br />
F. Liew<br />
IL-17 and kynurenines in pathogenic<br />
inflammation<br />
L. Romani<br />
Coffee Break / Exhibition<br />
Parallel Symposium 1:<br />
Allergy<br />
Chair: R. Valenta, J. Kalden<br />
Human Th17 cells<br />
S. Romagnani<br />
Greiner Bio-One GmbH | Bad Haller Straße 32 | A-4550 Kremsmünster | Phone: (+43) 75 83 67 91-0 | Fax: (+43) 75 83 63 18 | E-Mail: offi ce@at.gbo.com<br />
New facets in mast cell activation<br />
S. Bulfone-Paus<br />
From allergens to vaccines<br />
R. Valenta<br />
20<br />
www.gbo.com/preanalytics
Scientific <strong>Programm</strong>e – Saturday, September 6, 2008<br />
Time Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />
10.30<br />
-<br />
12.15<br />
Autoimmunity II<br />
Chair: R. Schwinzer,<br />
G. Staffler<br />
160. CCR7 is essential for regulatory<br />
T cell function in anti-<br />
GBM glomerulonephritis<br />
K. Hochegger, A. Rosenkranz,<br />
A. Rot<br />
161. The nuclear receptor<br />
PPARgamma serves as an intrinsic<br />
regulator of Th17 cell differentiation<br />
L. Klotz , , I. Dani, S. Burgdorf,<br />
A. Waisman, G. Eberl,<br />
J. Alferink, B. Langhans,<br />
T. Klockgether, P. Knolle<br />
162. Spontaneous CD8+ T Cell<br />
Mediated Liver Inflammation in<br />
a Transgenic Mouse Model of<br />
Autoimmune Hepatitis<br />
M. Zierden, E. Kühnen,<br />
M. Odenthal, H. P. Dienes<br />
163. Peripheral T cells are the<br />
therapeutic targets of highdose<br />
glucocorticoids in experimental<br />
autoimmune<br />
encephalomyelitis<br />
S. Wüst, J. van den Brandt,<br />
J. P. Tuckermann, R. Gold,<br />
H. M. Reichardt, F. Lühder<br />
164. The proteasome inhibitor<br />
bortezomib depletes plasma<br />
cells and protects lupus mice<br />
from nephritis<br />
K. Neubert, S. Meister,<br />
K. Moser, F. Weisel, D. Maseda,<br />
K. Amann, T. H. Winkler,<br />
J. R. Kalden, R. E. Voll<br />
165. CD8 T cells specific for a<br />
glomerular antigen induce renal<br />
inflammation in a CD4 help dependent<br />
fashion and may<br />
cause progressing Glomerulonephritis<br />
F. Heymann, E. E. Hamilton-<br />
Williams, I. Ludwig-Portugall,<br />
S. Quaggin, J. Flöge, H. Gröne,<br />
C. Kurts<br />
166. A new model for inflammatory<br />
bowel disease: A transgenic<br />
mouse expressing a<br />
crossreactive T cell receptor<br />
recognizing murine and bacterial<br />
HSP60<br />
N. Schmidt, T. Joeris,<br />
U. Steinhoff<br />
167. NAADP/Ca 2+ signaling: a<br />
new therapeutic target for T cell<br />
mediated autoimmune disease<br />
F. Odoardi, C. Cordiglieri,<br />
W. Dammermann, B. Zhang,<br />
M. Hohenegger, B. V. Potter,<br />
A. Guse, A. Flügel<br />
Infection II<br />
Chair: V. Leksa,<br />
O. Sharif<br />
168. Immunemodulation by<br />
Siglec-E during Trypanosoma<br />
cruzi infection<br />
H. Erdmann, P. R. Crocker,<br />
B. Fleischer, T. Jacobs<br />
169. A novel Leishmania major<br />
amastigote culture system<br />
U. A. Wenzel, S. Möller,<br />
M. Klinger, S. Liebau, T. Laskay,<br />
G. van Zandbergen<br />
170. The elimination of<br />
Anaplasma phagocytophilum in<br />
vivo requires CD4+ T cells, but<br />
is independent of Th1 cytokines<br />
and a wide spectrum of<br />
effector mechanisms<br />
K. Birkner, Y. Kern, B. Steiner,<br />
C. Bogdan, F. D. von Loewenich<br />
171. Oxidized phospholipids inhibit<br />
phagocytosis via a PKA<br />
dependent mechanism<br />
U. Matt, O. Sharif, T. Furtner,<br />
K. Stich, A. Zivkovic, S. Knapp<br />
172. Control of Persistent HBV<br />
Infection by Hepatitis B Core<br />
Antigen-activated NK cells:<br />
A Possible Mechanism for the<br />
HBV Persistence<br />
L. Huang, P. Chen, P. Knolle<br />
173. Acute infection with a single<br />
hepatitis C virus strain in<br />
dialysis patients: analysis of<br />
adaptive immune response and<br />
its impact on viral sequence<br />
evolution<br />
L. Weseslindtner,<br />
C. Neumann-Haefelin, S. Viazov,<br />
A. Haberstroh, J. Kletzmayr,<br />
J. H. Aberle, J. Timm,<br />
S. R. Ross, R. Klauser-Braun,<br />
T. F. Baumert, M. Roggendorf,<br />
R. Thimme, H. Holzmann<br />
174. Type I Interferons as virulence-determining<br />
factors in<br />
Listeria monocytogenes infections<br />
B. Reutterer, S. Stockinger,<br />
A. Pilz, D. Soulat, R. Kastner,<br />
S. Westermayer, T. Rülicke,<br />
M. Müller, T. Decker<br />
126. Yersinia enterocolitica differently<br />
affects DC subpopulations<br />
in vivo<br />
S. E. Autenrieth, T. Linzer,<br />
P. Warnke, S. Schmitz,<br />
I. B. Autenrieth<br />
Complement System<br />
Chair: M. Kirschfink,<br />
M. Wahrmann<br />
176. Human factor H-related<br />
protein 4 (CFHR4) recruits Creactive<br />
protein to the surface<br />
of necrotic cells<br />
M. Mihlan, M. Hebecker,<br />
M. Huber-Lang, R. Dahse,<br />
P. F. Zipfel, M. Józsi<br />
177. Regulation of mouse ficolin-B<br />
expression in immune<br />
competent cells<br />
V. L. Runza, J. Kürchner,<br />
D. Weber-Steffens,<br />
D. N. Männel<br />
178. Functional analyses indicate<br />
pathogenic role of factor<br />
H autoantibodies in atypical<br />
hemolytic uremic syndrome<br />
S. Strobel, P. F. Hoyer,<br />
C. J. Mache, E. Sulyok,<br />
P. F. Zipfel, M. Józsi<br />
179. A dual role of the C5a receptor<br />
(C5aR) in acute and<br />
chronic dextran sulphate induced<br />
models of inflammatory<br />
bowel disease<br />
K. Johswich, M. Martin,<br />
A. Bleich, M. Kracht,<br />
O. Dittrich-Breiholz, E. Gessner,<br />
S. Suerbaum, C. Rheinheimer,<br />
A. Klos<br />
180. Candida albicans CaHGT1<br />
and its role in complement inhibition<br />
and modulation of other<br />
virulence factors<br />
I. Lesiak, G. Vogl,<br />
T. Schwarzmüller, M. P. Dierich,<br />
K. Kuchler, R. Würzner<br />
P419. Characterization of factor<br />
H binding to neutrophil granulocytes<br />
J. Losse, P.F. Zipfel, M. Józsi<br />
182. Rituximab-induced ADCC<br />
of tumour cells is variably<br />
modified by complement iC3b<br />
A. Dörr, C. Watzl,<br />
M. Kirschfink<br />
Cytokines, Chemokines &<br />
their receptors<br />
Chair: U. Höpken,<br />
M. Sibilia<br />
21<br />
183. gp130 on<br />
macrophages/neutrophils negatively<br />
regulates Th17 development<br />
during experimental<br />
tuberculosis<br />
J. Sodenkamp, I. Foerster,<br />
W. Mueller, C. Hoelscher<br />
184. The role of optineurin<br />
(FIP2) in adenovirus E3-14.7Kmediated<br />
inhibition of TNFR1<br />
apoptosis<br />
L. Klingseisen, G. Knoll,<br />
W. Schneider-Brachert<br />
185. Overlapping functions of<br />
IL-7 and TSLP in lymphoid development<br />
D. Finke, L. Flueck, A. G. Farr,<br />
A. G. Rolink, S. Chappaz<br />
186. Organ-specific suppression<br />
of CCL17 production<br />
through Interferon-<br />
T. Globisch, S. Stutte,<br />
V. Lukacs-Kornek, C. Kurts,<br />
I. Förster<br />
187. Down-regulation of IFNduring<br />
HPV-induced carcinogenesis<br />
B. Rincon-Orozco, F. Rösl<br />
188. An IFN reporter mouse<br />
model for the visualization of<br />
the initiation of the Type I interferon<br />
response in vivo<br />
P. Dresing, S. Scheu,<br />
R. M. Locksley<br />
189. Chemokine receptor CCR7<br />
contributes to a rapid and efficient<br />
clearance of lytic MHV-68<br />
from the lung while bronchusassociated<br />
lymphoid tissue harbors<br />
virus during latency<br />
J. R. Kocks, H. Adler,<br />
H. Danzer, K. Hoffmann,<br />
D. Jonigk, U. Lehmann,<br />
R. Förster<br />
190. IL-27 acts as a Priming<br />
Signal on Human Keratinocytes<br />
and Antigen- Presenting Cells<br />
J. Zeitvogel, T. Werfel,<br />
M. Wittmann
Immunity for Life<br />
Immunology for Health<br />
Venue<br />
International Congress Center Berlin (ICC Berlin)<br />
Neue Kantstraße / Ecke Messedamm<br />
14057 Berlin, Germany<br />
www.icc-berlin.de<br />
Under the auspices of EFIS<br />
2 nd European Congress<br />
of Immunology<br />
Congress President<br />
Prof. Dr. med. Reinhold E. Schmidt<br />
Medizinische Hochschule Hannover<br />
Klinik <strong>für</strong> Immunologie <strong>und</strong> Rheumatologie<br />
Carl-Neuberg-Straße 1<br />
30625 Hannover, Germany<br />
Phone: +49 (0)511– 532-6656<br />
Fax: +49 (0)511– 532-9067<br />
E-Mail: immunologie@mh-hannover.de<br />
September 13 – 16, 2009<br />
Berlin, Germany<br />
Congress Secretariat<br />
K.I.T. GmbH Association & Conference<br />
Management Group & Co. KG<br />
Kur<strong>für</strong>stendamm 71<br />
10709 Berlin, Germany<br />
Phone: +49 (0)30 – 246 03-0<br />
Fax: +49 (0)30 – 246 03-200<br />
E-Mail: eci2009@kit-group.org<br />
www.kit-group.org<br />
www.eci-berlin2009.com
Scientific <strong>Programm</strong>e – Saturday, September 6, 2008<br />
Time Lecture Hall 1<br />
10.30<br />
-<br />
12.45<br />
12.45<br />
-<br />
13.00<br />
Satellite Lunch Symposium - Phadia<br />
Vom rekombinanten Allergen zu neuen Allergietherapien<br />
Chair: R. Valenta, N. Reider<br />
Rekombinante Allergene: Vom Beginn zur Gegenwart<br />
H. Breiteneder<br />
Rekombinante Nahrungsmittelallergene<br />
K. Hoffmann-Sommergruber<br />
Klinische Anwendungen <strong>für</strong> rekombinante Allergene<br />
P. Schmid-Grendelmeier<br />
Klinische Erfahrungen mit Allergenchips<br />
J. M. Baron<br />
Die Komplexitaet von zellulären Allergietesten<br />
J. Kleine-Tebbe<br />
Immuntherapie <strong>und</strong> Verlaufkontrolle mit rekombinanten Allergenen<br />
G. Pauli<br />
Pause (mit Snack)<br />
Time Lecture Hall 1<br />
13.00<br />
-<br />
13.45<br />
14.00<br />
-<br />
14.30<br />
Klinische Fälle aus der <strong>Allergologie</strong>: Wie hätten Sie entschieden?<br />
Chair: Z. Szepfalusi, G. Pauli<br />
Werner Aberer, Reinhart Jarisch, Felix Wantke <strong>und</strong> Stefan Wöhrl präsentieren klinische Fälle aus der <strong>Allergologie</strong><br />
Best Poster Awards<br />
Chair: J. Smolen, S. Meuer<br />
Time Lecture Hall 2<br />
15.00 General Assembly ÖGAI<br />
Chair: J. Smolen, M. Säemann<br />
23
Warum soll ich in die Ferne schweifen,<br />
wenn mir ein Diagnostik unternehmen<br />
alles bietet, was ich brauche?<br />
Siemens Healthcare Diagnostics. Das Engagement, um Ihren<br />
individuellen Bedürfnissen auf den Gr<strong>und</strong> zu gehen.<br />
Oberste Priorität hat <strong>für</strong> Sie eine optimale Patientenbetreuung, <strong>und</strong> <strong>für</strong> uns, Ihnen dabei zu helfen, dieses<br />
Ziel zu erreichen. Dazu bietet Ihnen Siemens ein beachtliches Portfolio leistungsorientierter Systeme, ein<br />
umfangreiches Testmenü sowie innovative IT- <strong>und</strong> Servicelösungen an. Sprechen Sie mit unserem<br />
Expertenteam über Ihre Vorstellungen – gemeinsam finden wir die optimale Lösung <strong>für</strong> Sie. Treten Sie<br />
näher: www.siemens.com/customer-first<br />
Answers for life.<br />
A91DX-0701169-A1-0000 © 2008 Siemens Healthcare Diagnostics Inc. All rights reserved.
Poster Viewing 25<br />
Thursday, September 4, 2008<br />
09.30 – 10.30 hrs<br />
T-Lymphocytes I<br />
Chair: B. Jahn-Schmid, C. Scheinecker<br />
P001 – P028<br />
T-Lymphocytes II<br />
Chair: W. Pickl, H. Stockinger<br />
P029 – P056<br />
Innate Immunity: Antigen-Presenting Cells<br />
Chair: T. Weichhart, M. Gilliet<br />
P057 - P075<br />
Signal Transduction<br />
Chair: L.J. Berg, W. Ellmeier<br />
P076 - P094<br />
Tumor Immunology<br />
Chair: O.J. Finn, T. Blankenstein<br />
P095 - P117<br />
Thursday, September 4, 2008<br />
15.30 – 16.30 hrs<br />
Innate Immunity: Regulation<br />
Chair: M. Zeyda, S. Beissert<br />
P118 - P134<br />
Pattern Recognition Receptors & Myeloid Cells<br />
Chair: F. Schmitz, J. Stöckl<br />
P135 - P151<br />
NK Cells<br />
Chair: C. Watzl, V. Sexl<br />
P152 - P164<br />
Vaccines & Adjuvants<br />
Chair: H. Lassmann, T. Weichhart<br />
P165 - P187<br />
Immunomodulation<br />
Chair: M. Fischer, G. Zlabinger<br />
P188 - P208<br />
Friday, September 5, 2008<br />
09.30 – 10.30 hrs<br />
Alloimmunity & Tolerance<br />
Chair: G. Böhmig, M. Säemann<br />
P209 - P233<br />
Allergy<br />
Chair: B. Bohle, S. Bulfone-Paus<br />
P234 - P264<br />
Infection<br />
Chair: U. Schaible, S. Knapp<br />
P265 - P296<br />
Mucosal Immunity<br />
Chair: S. Meuer, P. Brandtzaeg<br />
P297 - P308<br />
Friday, September 5, 2008<br />
15.30 – 16.30 hrs<br />
Autoimmunity I<br />
Chair: R. Germain, E. Sercarz<br />
P309 - P329<br />
Autoimmunity II<br />
Chair: G. Steiner, J. Kalden<br />
P330 - P352<br />
Complement System and B-Lymphocytes<br />
Chair: F. Melchers, A. Radbruch<br />
P420 and P353 - P360<br />
Regulatory Lymphocytes<br />
Chair: L. Klein, R. Bacchetta<br />
P361 - P383<br />
Cytokines, Chemokines & their receptors<br />
Chair: F.Y. Liew, L. Romani<br />
P384 - P404<br />
Veterinary Immunology<br />
Chair: B. Kaspers, A. Saalmüller<br />
P405 - P418
Business Meetings<br />
As per date of printing<br />
Closed Business Meetings<br />
Wednesday, September 3, 2008<br />
10.00 – 12.00 hrs Steering Committee Meeting ECI 2009 Lecture Room 25 / Level 8<br />
12.00 – 14.30 hrs Vorstandssitzung DGfI Hotel Regina – Salon Makart<br />
Thursday, September 4, 2008<br />
11.00 – 13.00 hrs Promotion Committee Meeting des ECI 2009 Lecture Room 25 / Level 8<br />
12.30 – 14.00 hrs Sitzung der DGfI Kommission “Fachimmunologe” Lecture Room 13 / Level 7<br />
Friday, September 5, 2008<br />
12.00 – 14.00 hrs Arbeitskreise der DGfI Lecture Room 25 / Level 8<br />
Saturday, September 6, 2008<br />
09.00 – 11.00 hrs DGfI Educational Committee Lecture Room 25 / Level 8<br />
26
Satellite Lunch Symposia<br />
Thursday, September 4, 2008, 12.15 – 13.45 hrs, Lecture Hall 1<br />
B cell: Promising target in autoimmune diseases<br />
Chair: J. Smolen<br />
The biology of the B cell in autoimmune diseases<br />
A. Radbruch<br />
Clinical experiences with B cell therapies<br />
T. Dörner<br />
Safety: Experiences with Rituximab<br />
H-P. Brezinsek<br />
Friday, September 5, 2008, 12.15 – 13.45 hrs, Lecture Hall 2<br />
Immune modulation with intravenous immunoglobulin: the<br />
established and the advances<br />
Chair: S. Meuer<br />
Introduction<br />
S. Meuer<br />
Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and<br />
autoimmune diseases<br />
P. Imbach<br />
Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacy<br />
F. Nimmerjahn<br />
Basic research in human immunology creates new therapeutic options<br />
S. Meuer<br />
Discussion and wrap-up<br />
Saturday, September 6, 2008, 10.30 – 12.45 hrs, Lecture Hall 1<br />
Vom rekombinanten Allergen zu neuen Allergietherapien<br />
Chairs: R. Valenta, N. Reider<br />
Rekombinante Allergene: Vom Beginn zur Gegenwart<br />
H. Breiteneder<br />
Rekombinante Nahrungsmittelallergene<br />
K. Hoffmann-Sommergruber<br />
Klinische Anwendungen <strong>für</strong> rekombinante Allergene<br />
P. Schmid-Grendelmeier<br />
Klinische Erfahrungen mit Allergenchips<br />
J.M. Baron<br />
Die Komplexitaet von zellulaeren Allergietesten<br />
J. Kleine-Tebbe<br />
Immuntherapie <strong>und</strong> Verlaufkontrolle mit rekombinanten Allergenen<br />
G. Pauli<br />
12.45 - 13.00 Pause (mit Snack)<br />
13.00 - 13.45 Klinische Fälle aus der <strong>Allergologie</strong>: „Wie hätten Sie entschieden”<br />
27
Information on Posters<br />
Poster Topics<br />
P01 T-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P001 – P056<br />
P02 Innate Immunity: Antigen-Presenting Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P057 – P075<br />
P03 Signal Transduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P076 – P094<br />
P04 Tumor Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P095 – P117<br />
P05 Innate Immunity: Regulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P118 – P134<br />
P06 Pattern Recognition Receptors & Myeloid Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P135 – P151<br />
P07 NK cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P152 – P164<br />
P08 Vaccines & Adjuvants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P165 – P187<br />
P09 Immunomodulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P188 – P208<br />
P10 Alloimmunity & Tolerance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P209 – P233<br />
P11 Allergy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P234 – P264<br />
P12 Infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P265 – P296<br />
P13 Mucosal Immunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P297 – P308<br />
P14 Autoimmunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P309 – P352<br />
P15 B-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P353 – P360<br />
P16 Regulatory Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P361 – P383<br />
P17 Cytokines, Chemokines & their receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P384 – P404<br />
P18 Veterinary Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P405 – P418<br />
P19 Complement system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P420 – P420<br />
Posters will be on display from Wednesday, September 3, (15.00 hrs) to Saturday, September 6, 2008,<br />
(15.00 hrs).<br />
Poster mounting will be possible on: Wednesday, September 3, 2008 from 10:00 - 15:00.<br />
Removal will be possible on: Saturday, September 6, 2008 from 14:30 - 15:30.<br />
Please note that posters not removed by then, will be taken down by conference staff and will not be<br />
stored or forwarded to the authors after the meeting.<br />
You will find your poster board number in the author index at the end of the abstract book.<br />
Presence at Posters<br />
In order to enable discussion and interaction with other participants, we request you or another member of your<br />
group to be at your poster board at the following times:<br />
Thursday, September 4, 2008, 09.30 – 10.30 hrs<br />
T-Lymphocytes-1 P001 - P028<br />
T-Lymphocytes-2 P029 - P056<br />
Innate Immunity: Antigen-Presenting Cells P057 - P075<br />
Signal Transduction P076 - P094<br />
Tumor Immunology P095 - P117<br />
Thursday, September 4, 2008, 15.30 – 16.30 hrs<br />
Innate Immunity: Regulation P118 - P134<br />
Pattern Recognition Receptors & Myeloid Cells P135 - P151<br />
NK Cells P152 - P164<br />
Vaccines & Adjuvants P165 - P187<br />
Immunomodulation P188 - P208<br />
Friday, September 5, 2008, 09.30 – 10.30 hrs<br />
Alloimmunity & Tolerance P209 - P233<br />
Allergy P234 - P264<br />
Infection P265 - P296<br />
Mucosal Immunity P297 - P308<br />
Friday, September 5, 2008 15.30 – 16.30 hrs<br />
Autoimmunity-1 P309 - P329<br />
Autoimmunity-2 P330 - P352<br />
B-Lymphocytes P353 - P360<br />
Regulatory Lymphocytes P361 - P383<br />
Cytokines, Chemokines & their receptors P384 - P404<br />
Veterinary Immunology P405 - P418<br />
Complement System P420<br />
If this is not possible, please leave a note on your poster board detailing the times when you will be present at the board.<br />
28
Information for Speakers<br />
Projection and Technical Setting<br />
All rooms will be equipped with data- and overhead projection (no slides).<br />
It is essential that you load and view your presentation in the slide preview room preferably in the<br />
morning of the day your talk is scheduled, but no later than 2 hours in advance.<br />
The lecture rooms are exclusively equipped with Windows-PCs (no Macintosh machines). In case you<br />
absolutely need to use your own laptop or notebook, please contact the preview center well in advance<br />
of your talk.<br />
Please bring a USB-stick or CD-ROM, all formatted for Windows® (PC). You may want to carry a second<br />
disk/CD as a back-up in case there is any unsolvable technical problem.<br />
File Format: Microsoft® Power Point presentation formatted for Windows® (PC) only. (Operating<br />
system: Windows XP®)<br />
Preferred Resolution: XGA (1024 x 768 pixel)<br />
Preview Room<br />
The Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of your<br />
presentation is available in the preview room. All presenters should bring their electronic presentation to the preview<br />
room preferably in the morning of the day of the talk, but no later than 2 hours before the start of the session. For<br />
sessions starting at 08.15 hrs, the PowerPoint presentations should be handed in the previous day.<br />
Opening hours of the preview room:<br />
Wednesday, September 3, 2008 12.00 – 18.00<br />
Thursday, September 4, 2008 07.30 – 18.00<br />
Friday, September 5, 2008 07.30 – 18.00<br />
Saturday, September 6, 2008 08.15 – 15.00<br />
<strong>Programm</strong>e Changes<br />
The organisers cannot assume any liability for changes in the programme due to external or unforeseen<br />
circumstances.<br />
29
Congress Information<br />
Abstract Books<br />
You will find an Abstract Book in your conference bag.<br />
Accreditation<br />
The Joint Annual Meeting of Immunology has applied for credits at the European Accreditation Council for Continuing<br />
Medical Education, Institution of the UEMS.<br />
The number of credits (which will be announced after the meeting) will figure on the respective confirmation,<br />
which will also be sent after the meeting.<br />
The rules of the EACCME state that participants are kindly asked to fill in the feedback (evaluation) form included<br />
in the conference bag. It can be returned to the registration desk.<br />
Participants applying for EACCME Credits will have to have their badge scanned daily at the registration<br />
desk before entering the conference. The confirmation will be mailed after the conference at the end of<br />
September.<br />
Die österreichische Akademie der Ärzte hat an diese Veranstaltung 41 Diplomfortbildungspunkte<br />
vergeben.<br />
Admission to Lecture Halls<br />
Participants are requested to enter the lecture halls via Level 8 only.<br />
Badges<br />
Participants will receive their name badges from the conference registration desk. Since only registered participants will be permitted<br />
to attend scientific sessions, the exhibition and poster areas, you are kindly asked to wear your badge when entering the<br />
congress venue. Please note that admission to scientific sessions is strictly restricted to participants wearing their badges. Exhibitors<br />
and accompanying persons are not entitled to attend the scientific sessions. Lost badges can be replaced at the registration<br />
desk. However, a handling fee of € 20,- will be charged.<br />
The following badge-colours are used at the Congress:<br />
White � Participants<br />
Yellow � Accompanying Persons<br />
Green � Exhibitors<br />
Red � Staff<br />
Cancellations and Ref<strong>und</strong>s<br />
Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.<br />
The policy for ref<strong>und</strong>ing registration fees is as follows:<br />
Written cancellation received:<br />
- before July 31, 2008: 75% ref<strong>und</strong><br />
- after July 31, 2008: no ref<strong>und</strong><br />
The date of the postmark or fax ID is the basis for considering ref<strong>und</strong>s. Ref<strong>und</strong>s will be made after the congress.<br />
Cash Bar<br />
Snacks and drinks may be purchased at the cash bar on Level 8 during congress hours.<br />
Certificate of Attendance<br />
Confirmations of attendance will be issued at the registration desk.<br />
City Tour<br />
The city tour “Classical Vienna – A City Stroll” will take place on Thursday, September 4, 2008. It is free of charge for accompanying<br />
persons, however, registration in advance is mandatory.<br />
Coffee Breaks<br />
During the session breaks, refreshments will be served free of charge to participants wearing name badges.<br />
Exhibition Opening Hours<br />
Wednesday, September 3, 2008 15.00 – 17.00 hrs<br />
Thursday, September 4, 2008 08.15 – 17.00 hrs<br />
Friday, September 5, 2008 08.15 – 17.00 hrs<br />
Saturday, September 6, 2008 08.45 – 15.00 hrs<br />
Hotel and Tours Desk<br />
Mondial, the official travel agency of the meeting, will be present at the conference on<br />
Wednesday, September 3, 2008 from 14.30 – 17.30 hrs and on<br />
Thursday, September 4, 2008 from 07.30 – 09.30 hrs.<br />
If you have any questions regarding your hotel booking or the city tour, please approach Mondial. They will be located near the<br />
registration desk.<br />
Internet<br />
A few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internet<br />
cafés throughout the city.<br />
30
Congress Information<br />
Message Board<br />
A Message Board and notice of the daily programme are available on Level 7 and Level 8.<br />
Poster Mounting and Removal<br />
There are four poster sessions: Thursday and Friday from 09.30 – 10.30 hrs and from 15.30 – 16.30 hrs. Poster mounting will be<br />
possible on Wednesday, September 3, 2008 from 10.00 – 15.00 hrs. Poster removal will be possible on Saturday, September 6,<br />
2008 from 14.30 – 15.30 hrs. Please note that the organisers cannot assume any liability for loss or damage of posters displayed<br />
in the poster area. Posters that are not removed by 15.30 hrs on Saturday, September 6, 2008 will be removed by staff and will<br />
not be stored or forwarded to the author after the meeting.<br />
Preview Room<br />
The Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of your presentation<br />
is available in the preview room. All presenters should bring their electronic presentation to the preview room preferably in<br />
the morning of the day of the talk, but not later than 2 hours before the start of the session. For sessions starting at 08.15 hrs,<br />
the PowerPoint presentations should be handed in the previous day.<br />
Following are the opening hours of the preview room:<br />
Wednesday, September 3, 2008 12.00 – 18.00<br />
Thursday, September 4, 2008 07.30 – 18.00<br />
Friday, September 5, 2008 07.30 – 18.00<br />
Saturday, September 6, 2008 08.15 – 15.00<br />
Public Transport<br />
Registered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all public<br />
transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for going<br />
to the airport, since the airport is out of town. Congress participants are kindly requested to return their ticket if it is not needed.<br />
Registration Desk opening hours<br />
Wednesday, September 3, 2008 10.00 – 18.00<br />
Thursday, September 4, 2008 07.30 – 18.00<br />
Friday, September 5, 2008 07.30 – 18.00<br />
Saturday, September 6, 2008 08.15 – 15.00<br />
Smoking Policy<br />
The Joint Annual Meeting of Immunology is a “No-smoking-Conference”. Please note that smoking is banned from all public<br />
buildings. Restaurants and bars may, depending on size, be declared either as “smoking” or “no-smoking” locations or have<br />
separate areas and ventilation systems.<br />
Staff<br />
Should you have any questions, congress staff, recognizable by a blue t-shirt and red badge, will be pleased to help you.<br />
31
Registration Fees<br />
Onsite registration<br />
Wednesday, September 3, 2008 10.00 – 18.00<br />
Thursday, September 4, 2008 07.30 – 18.00<br />
Friday, September 5, 2008 07.30 – 18.00<br />
Saturday, September 6, 2008 08.15 – 15.00<br />
Payment received before June 15, 2008 after June 15, 2008 and on-site<br />
Members EUR 190.— EUR 300.—<br />
Student Members* EUR 95.— EUR 135.—<br />
Non-Members EUR 280.— EUR 390.—<br />
Student Non-Members* EUR 140.— EUR 180.—<br />
Accompanying Persons EUR 60.— EUR 60.—<br />
Day Ticktet Member EUR 140,—<br />
Day Ticket Non-Member EUR 180,—<br />
* please provide a copy of an ID together with your registration<br />
What is covered by the registration fee?<br />
Participants Accompanying persons<br />
Admission to all scientific sessions<br />
Access to the exhibition<br />
Coffee breaks<br />
Welcome reception at the City Hall<br />
Thursday, September 4, 2008, 19.00 hrs<br />
Abstract book<br />
<strong>Programm</strong>e<br />
4-days public transport ticket<br />
Payment of registration fees may be made in cash (Euros only), by maestro debit card, or by the following credit cards:<br />
Diners Club, Mastercard, Visa.<br />
Please note that the reduced registration fee is only applicable if it has been credited to the congress account before the deadline.<br />
Registering without performing an actual payment is not sufficient to benefit from the reduction. Pre-registration without<br />
payment of the registration fee is possible. The full fee is to be paid at the registration desk.<br />
Cancellations and ref<strong>und</strong>s:<br />
Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.<br />
Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.<br />
The policy for ref<strong>und</strong>ing registration fees is as follows:<br />
Written cancellation received:<br />
- before July 31, 2008: 75% ref<strong>und</strong><br />
- after July 31, 2008: no ref<strong>und</strong><br />
The date of the postmark or fax ID is the basis for considering ref<strong>und</strong>s. Ref<strong>und</strong>s will be made after the congress.<br />
32<br />
Admission to the welcome reception at the City Hall<br />
Thursday, September 4, 2008, 19.00 hrs<br />
Classical Vienna City Tour*,<br />
Thursday, September 4, 2008, 09.00 hrs<br />
Access to the exhibition and coffee breaks<br />
(no admission to lectures)<br />
*Please note that the classical city tour is not available for<br />
on site registrations of accompanying persons.
General Information<br />
Bank services - Money matters<br />
Banks are open from 8.30 – 12:30 and from 13:30 – 15:00, Monday to Friday. Some banks are also open on Thursday afternoons<br />
until 17:30 hrs. Cash machines (ATMs), which accept all major international bank cards, are available throughout the city. There<br />
is a cash machine in the main entrance of the Vienna General Hospital. The currency of Austria is the Euro (€). Major credit cards<br />
are widely accepted, but please always check beforehand.<br />
Car Parking<br />
The Vienna General Hospital has approximately 800 car parking spaces available for visitors in an <strong>und</strong>ergro<strong>und</strong> car park. The<br />
entrance is at Währinger Gürtel.<br />
Eating out in Vienna<br />
Vienna has a broad variety of local and international restaurants, many of them located in the old city and in the vicinity of the conference<br />
venue.<br />
Emergency services<br />
The phone number to dial for emergencies is 112.<br />
GSM cell phone roaming<br />
GSM cell/mobile phone roaming is available without any problems for all major international providers. It is advisable to inquire<br />
beforehand at your provider which roaming company in Austria offers the cheapest tariffs.<br />
Insurance<br />
In registering for the Joint Annual Meeting of Immunology 2008 participants agree that neither the organising committee nor<br />
the congress office assume any liability whatsoever. Participants are requested to make their own arrangements for health and<br />
travel insurance.<br />
Internet and printing facilities<br />
A few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internet<br />
cafés throughout the city.<br />
Language<br />
The official language of the congress will be English (no simultaneous translation).<br />
Medical care<br />
The Austrian National Health Service may be used by all persons from European Union countries who have the E111 Form (EHI-<br />
Card). This form/card should be obtained at the health service or post office of the visitor’s home country before travelling to<br />
Austria. It is advisable for participants from countries outside the European Union to take out medical insurance before reaching<br />
Austria, since they will be charged for access to the national health system.<br />
Pharmacies<br />
Medicines that do not require a medical prescription may be purchased over the counter. If you need advice, do not hesitate to<br />
ask the pharmacist. If you usually take medication, it is advisable to bring a sufficient amount with you for your trip. Pharmacies<br />
in the vicinity of the conference venue are on Zimmermannplatz 1, 1090 Vienna. There are duty pharmacies open 24 hours a day.<br />
Outside each pharmacy there is a list of the nearest duty pharmacies, or you may ask at your hotel reception for more information.<br />
Safety - Crime<br />
Visitor safety is generally adequate. Like in any other major European city, you can walk everywhere using common sense. Pick<br />
pocketing in heavily visited tourist zones or in public transport lines might be a concern.<br />
Unfortunately experience has shown that some basic precautionary measures should always be kept in mind in any city:<br />
- Do not carry important items like flight tickets, passports etc. with you when visiting the conference or strolling through the city;<br />
leave them in the hotel safe during your stay. Rather carry a photocopy of your passport or an identity card with you.<br />
- Try not to carry all documents, money, credit cards and other essential items and valuables in one bag. If it gets lost or stolen,<br />
everything will be gone and might be difficult to replace on short notice, especially passports and visa to return to your country<br />
of residence.<br />
- Take off your name badge when leaving the conference centre.<br />
Shops<br />
Shops in Vienna are generally open between 09.00 and 18.00 hrs Mon-Fri, and between 09.00 and 12.00 on Saturdays. Some<br />
shops are open until 19.00 Mon-Fri and until 17.00 on Saturdays. Shops are usually closed on S<strong>und</strong>ays, except for a few establishments<br />
with special permits.<br />
Taxis<br />
There are Taxi ranks throughout the city, but calling is often your best option. Please address your hotel reception or the registration<br />
desk of the conference venue. A taxi station can be fo<strong>und</strong> in front of the main entrance at Level 5 and at Lazarettgasse<br />
(exit on Level 4).<br />
Tipping<br />
Tips are not obligatory in Austria, although people usually tip approximately 10% at restaurants, cafés and bars. Hotel and airport<br />
porters will accept tips, depending on the luggage.<br />
33
General Information<br />
Travelling within Vienna<br />
Registered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all public<br />
transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for going<br />
to the airport, since it is out of town. Congress participants are kindly requested to return their ticket if it is not needed.<br />
For accompanying persons and exhibitors tickets are available from machines at <strong>und</strong>ergro<strong>und</strong> stations (maestro debit cards accepted),<br />
at news agents’, or at Vienna Transport Authority’s ticket offices. Tickets bought in advance are cheaper and must be<br />
punched in a blue ticket cancelling machine on the tram or bus, or at the barrier before boarding the <strong>und</strong>ergro<strong>und</strong> train.<br />
Single trip tickets can be used for any single trip within Vienna. You may change lines (and switch between bus, tram, <strong>und</strong>ergro<strong>und</strong>,<br />
or urban train), but you may not interrupt your journey. Ticket price: EUR 1.70 when bought in advance; EUR 2.20 when<br />
bought in the means of transport.<br />
The 24-hour pass is valid throughout Vienna for exactly 24 hours from the time it is punched. Price: EUR 5.70<br />
The 72-hour pass is valid throughout Vienna for exactly 72 hours from the time it is punched. Price: EUR 13.60<br />
The 8-day ticket is valid for any eight days, not necessarily eight consecutive days. It is a rover ticket, which means you can travel<br />
all aro<strong>und</strong> Vienna. You can also use the ticket for several people travelling together. Simply punch one strip for each person in the<br />
group. Price: EUR 27.20<br />
Week-pass valid from Monday to Monday, 09.00 hrs. Price: EUR 14.00<br />
A taxi is the most comfortable way of getting aro<strong>und</strong> the city but also the most expensive. They are identifiable by their roof-sign<br />
which is lit when available. Prices must be displayed inside the cab and meters (which are compulsory in all cabs) will indicate<br />
the fare.<br />
Travelling from and to the Airport<br />
Vienna International Airport is located 13 kilometres south east of Vienna.<br />
City Airport Train (CAT)<br />
The train service between the airport and the city centre (City Air Terminal – Station ‘Wien Mitte’) is every 30 minutes and takes<br />
16 minutes. It is covered from 6:05 hrs to 00:05 hrs (Airport to City) and from 5:38 hrs to 23:38 hrs (City to Airport). Tickets may<br />
be purchased online (EUR 8.00 single or EUR 15.00 return), from ticket machines at the airport/station (EUR 9.00 single or EUR<br />
16.00 return) or on board (EUR 10.00 single). From ‘Wien Mitte’ you can take the green line (U4) direction Heiligenstadt and get<br />
off at ‘Spittelau’ (five stops) and then take the brown line (U6) direction Siebenhirten and get off at Michelbeuern-Allgemeines<br />
Krankenhaus.<br />
Taxi fares to the conference venue are about EUR 35.00 and take aro<strong>und</strong> 25 minutes. There is a taxi rank outside the airport terminal.<br />
Night-time fees are slightly higher.<br />
Travelling to the Vienna General Hospital by Public Transportation<br />
The Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 (the brown line) and getting<br />
off at Michelbeuern – Allgemeines Krankenhaus. Furthermore, it can be reached by tramway 42, tramways 5 and 33 (stop<br />
Lazarettgasse) as well as tramways 43 and 44 (stop Alser Straße).<br />
Vienna<br />
Vienna, the capital of Austria, 2 million inhabitants, is situated on the banks of the Danube. Vienna is a dream city for anyone with<br />
an interest in history. Narrow, medieval alleyways and grand boulevards lead to historic sights such as the Imperial Palace (Hofburg),<br />
Belvedere Palace, Burgtheater, the Spanish Riding School, St. Stephen’s Cathedral, the Opera House, Karlskirche, or<br />
Schönbrunn Palace. Vienna has been synonymous with music for centuries, and was home to Mozart, Beethoven, Schubert and<br />
Johann Strauss. The Vienna Philharmonic Orchestra is one of the world’s top orchestras; the Vienna Boys’ Choir is triumphantly<br />
successful wherever it tours. Vienna possesses a lively and vast array of cultural attractions, from classical or experimental theatre,<br />
film or dance festivals, opera or operetta, to exhibitions and concerts. The Museum of Fine Arts is one of the world’s largest<br />
and most distinguished museums, housing priceless works of art. Art accompanies you wherever you go in Vienna - even some<br />
of its <strong>und</strong>ergro<strong>und</strong> stations are listed properties on account of their elegant, ornamental Jugendstil (Art Nouveau) style designed<br />
by Otto Wagner. For more information about Vienna, please see www.aboutvienna.org.<br />
34
Venue<br />
Location of the Vienna General Hospital and the Lecture Centre<br />
GENERAL INFORMATION<br />
Congress venue<br />
Vienna General Hospital<br />
Allgemeines Krankenhaus Wien<br />
Lecture Hall Centre<br />
Hörsaalzentrum<br />
Währinger Gürtel 18-20<br />
A-1090 Vienna, Austria<br />
HÖRSAALZENTRUM<br />
EBENE 07/08<br />
Public transportation in Vienna<br />
The Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 and getting off<br />
at the station ”Michelbeuern – Allgemeines Krankenhaus”. Furthermore it can be reached with the tramway 42, the<br />
tramway 5 and 33 (station ”Lazarettgasse”) as well as the tramways 43 and 44 (station ”Alser Strasse”)<br />
35
Venue 36<br />
Level 7<br />
Access from main entrance<br />
No entrance to Lecture Halls.<br />
Please use the doors on Level 8.<br />
Meeting<br />
Room 13<br />
Level 8<br />
Access to Lecture Halls<br />
? Entrance to Lecture Halls<br />
Escalators to main entrance<br />
Green Elevators to main entrance<br />
Lecture<br />
Hall 2<br />
?? ? ? ? ?<br />
Lecture<br />
Hall 1<br />
Lecture<br />
Hall 3<br />
? ? ? ? ? ?<br />
Coffee<br />
Escalators to main entrance<br />
Green Elevators to main entrance<br />
Lecture<br />
Hall 2<br />
Exhibition<br />
Registration<br />
Red Elevators<br />
Lecture<br />
Hall 5<br />
Lecture<br />
Hall 4<br />
Coffee<br />
e<br />
e<br />
f<br />
f<br />
o<br />
C<br />
n<br />
o<br />
i<br />
t<br />
i<br />
b<br />
i<br />
h<br />
x<br />
E<br />
?? ? ? ? ?<br />
Lecture<br />
Hall 1<br />
Lecture<br />
Hall 3<br />
? ? ? ? ? ?<br />
Posters and Exhibition<br />
Coffee<br />
Red Elevators<br />
Lecture<br />
Hall 5<br />
Lecture<br />
Hall 4<br />
Posters<br />
? ? ? ?<br />
s<br />
r<br />
e<br />
t<br />
s<br />
o<br />
P<br />
r<br />
a<br />
B<br />
h<br />
s<br />
a<br />
C<br />
n<br />
o<br />
i<br />
t<br />
i<br />
b<br />
i<br />
h<br />
x<br />
E<br />
Cloakroom<br />
Posters<br />
Preview<br />
Room<br />
Posters<br />
Meeting<br />
Room<br />
25<br />
Posters
Social Events<br />
Thursday, September 4, 2008, 19.00 hrs<br />
Welcome Reception by the Mayor of Vienna at the Vienna City Hall<br />
The mayor of the city of Vienna is pleased to invite you to a Welcome Reception. Meet your colleagues at this event. Enjoy the<br />
evening with a Buffet and live music.<br />
Dress code: business attire<br />
Attendance is free for registered participants and accompanying persons. Those who have registered prior to the congress<br />
should have received their ticket with the congress material. Please remember to bring your ticket.<br />
Please note that attendance is limited and advance registration is mandatory in order to receive a ticket!<br />
A limited number of tickets will still be available for onsite bookings.<br />
Venue: Vienna City Hall, Lichtenfelsgasse 2, 1010 Vienna<br />
Directions: From the conference venue take the brown <strong>und</strong>ergro<strong>und</strong> line U6 (direction Siebenhirten) one stop and get off at Alser<br />
Strasse. Take the tram 43 (direction Schottentor) and get off at Landesgerichtsstrasse. From there you can walk along Landesgerichtsstrasse<br />
until you reach the city hall on your left hand side. Walk past the city hall and turn left into Lichtenfelsgasse. The<br />
entrance to the reception is on your left.<br />
Alternatively you can take the brown <strong>und</strong>ergro<strong>und</strong> line U6 (direction ‘Floridsdorf’) three stops and get off at ‘Spittelau’. Take the<br />
green <strong>und</strong>ergro<strong>und</strong> line U4 (direction ‘Hütteldorf’) three stops and get off at ‘Schottenring’. Take the purple <strong>und</strong>ergro<strong>und</strong> line U2<br />
(direction ‘Karlsplatz’) two stops and get off at ‘Rathaus’. Take the exit towards the front of the train and turn left and cross the<br />
street. This is Lichtenfelsgasse. The entrance to the Reception is on the left hand side.<br />
Friday, September 5, 2008, 19.30 hrs.<br />
Dinner at a Viennese “Heuriger”<br />
An evening spent in typical Austrian wine taverns in Vienna. You will be served a delicious Austrian buffet and excellent local<br />
wines while enjoying the atmosphere of a traditionally decorated restaurant. “Heuriger” could be translated with “of this year”<br />
and means a young crisp wine produced during the current wine season. Only wine producers serving their own product,<br />
grown in the vineyards of Vienna, may call their tavern “Heuriger”.<br />
Dress code: casual<br />
Venue: Weingut Fuhrgassl Huber<br />
Neustift/Walde 68<br />
1190 Vienna<br />
Buses depart from the main entrance on Level 5 of the Vienna General Hospital, at 19.30 hrs and return in the late<br />
evening.<br />
Price per ticket including transport, music, food and beverages: EUR 45.–<br />
Please note that advance registration is mandatory in order to receive a ticket! A limited number of tickets will still be<br />
available for onsite bookings.<br />
37
Undergro<strong>und</strong> Map 38<br />
9<br />
Congress<br />
venue<br />
Welcome<br />
Reception
City Map 39<br />
��<br />
����������������������<br />
�����������������������<br />
�<br />
�<br />
1) Lecture Centre of the Vienna<br />
General Hospital (AKH)<br />
2) City Hall (Welcome Reception)<br />
3) Arcotel Boltzmann<br />
4) Mercure Josefshof<br />
5) Hotel & Palais Strudlhof<br />
6) Carlton Opera<br />
�<br />
�<br />
�<br />
�<br />
�<br />
��<br />
��<br />
�<br />
7) Wandl<br />
8) Atlas<br />
9) Academia<br />
10) Pension Ani Falstaff<br />
11) Pension Ani<br />
12) Regina<br />
13) Royal<br />
�<br />
��
Exhibition – General Information<br />
Exhibiton Organiser:<br />
Name MAW – Medizinische Ausstellungs- <strong>und</strong> Werbegesellschaft<br />
Address Freyung 6<br />
1010 Vienna, Austria<br />
Telephone Ms. Ingrid Winkler: +43 664 441 8285<br />
Ms. May-Britt Ernst: +43 664 105 2018<br />
Fax +43 1 535 6016<br />
E-mail maw@media.co.at<br />
Exhibition Dates & Opening hours:<br />
Wednesday, September 3, 2008 15.00 – 17.00 hrs<br />
Thursday, September 4, 2008 08.15 – 17.00 hrs<br />
Friday, September 5, 2008 08.15 – 17.00 hrs<br />
Saturday, September 6, 2008 08.45 – 15.00 hrs<br />
Poster Mounting, Poster Viewing, Poster Removal Hours<br />
Wednesday, September 3, 2008 – poster mounting 10.00 – 15.00 hrs<br />
Wednesday, September 3, 2008 – poster viewing 15.00 – 18.00 hrs<br />
Thursday, September 4, 2008 – poster viewing 08.15 – 18.00 hrs<br />
Friday, September 5, 2008 – poster viewing 08.15 – 18.00 hrs<br />
Saturday, September 6, 2008 – poster viewing 08.45 – 14.30 hrs<br />
Saturday, September 6, 2008 – poster removal 14.30 – 15.30 hrs<br />
Location<br />
Venue Lecture Centre of the Vienna General Hospital<br />
Exhibition Areas Level 7 and Level 8<br />
Address Währinger Gürtel 18-20, 1090 Vienna, Austria<br />
40
List of Sponsors, Exhibitors and Advertisers*<br />
Ärztezentrale Adressen- <strong>und</strong> Drucksortenverlag, Vienna, Austria<br />
Abd Serotec- Endeavour House, Oxon, United Kingdom<br />
Acris Antibodies, Hiddenhausen, Germany<br />
Active Motif Europe, Rixensart, Belgium<br />
Aesca Pharma, Traiskirchen, Austria<br />
Alk Abello Allergie – Service GmbH, Linz, Austria<br />
Allergopharma, Vienna, Austria<br />
AstraZeneca Österreich, Vienna, Austria<br />
Becton Dickinson Austria, Schwechat, Austria<br />
Bencard Allergie, Vienna, Austria<br />
Bender Medsystems, Vienna, Austria<br />
Biomedica, Vienna, Austria<br />
Bio-Rad Laboratories, Munich, Germany<br />
Biotest AG, Dreieich, Germany<br />
Biozym Biotech Trading, Vienna, Austria<br />
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany<br />
CellGenix Technologie Transfer, Freiburg, Germany<br />
Cell Kinetice, Lod, Israel<br />
2 nd European Congress of Immunology – ECI 2009<br />
eubio, Vienna, Austria<br />
Fermentas, St. Leon-Rot, Germany<br />
GE Healthcare Europe, Vienna, Austria<br />
Greiner Bio – One, Kremsmünster, Austria<br />
Hal Allergy, Vienna, Austria<br />
41<br />
*(as per printing date)
List of Sponsors, Exhibitors and Advertisers*<br />
Invitrogen, Karlsruhe, Germany<br />
Jackson ImmunoResearch Europe Ltd., Suffolk, United Kingdom<br />
LaVision BioTec, Bielefeld, Germany<br />
Mabtech AB, Nacka Strand, Sweden<br />
Ferdinand Menzl Medizintechnik, Vienna, Austria<br />
Miltenyi Biotec, Bergisch Gladbach, Germany<br />
NatuTec, Frankfurt am Main, Germany<br />
New England Biolabs, Frankfurt am Main, Germany<br />
Novartis Pharma, Vienna, Austria<br />
Octapharma, Lachen, Switzerland<br />
Partec, Görlitz, Germany<br />
PeproTech, Hamburg, Germany<br />
Phadia Austria, Vienna, Austria<br />
Porsche Austria<br />
ProFas, Regensburg, Germany<br />
Charles River Consulting, Sulzfeld, Germany<br />
Roche Austria, Vienna, Austria<br />
R + D Systems, Wiesbaden, Germany<br />
Siemens Medical Solutions Diagnostics, Vienna, Austria<br />
Stallergenes France, Antony Cedex, France<br />
Stemcell Technologies, Grenoble, France<br />
tebu – bio, Offenbach, Germany<br />
THP Medical Products, Vienna, Austria<br />
Werfen Austria, Vienna, Austria<br />
Wiley Blackwell, Weinheim, Germany<br />
Yakult Deutschland, Neuss Germany<br />
42<br />
*(as per printing date)
Notes<br />
Printed in Austria by: ROBIDRUCK, 1200 Vienna – www.robidruck.co.at
Das Immunglobulin in<br />
seiner natürlichen Form<br />
Natur<br />
weitergeben<br />
Zusammensetzung: 1 ml Intratect® enthält 50 mg Plasmaproteine vom Menschen, davon mind. 96 % IgG (57,2 % IgG1, 37,2 % IgG2, 3,1 % IgG3, 3,0 % IgG4). Höchstgehalt an IgA: 2 mg/ml. Hilfsstoffe: Glycin, Wasser zur<br />
Injektion. Anwendungsgebiete: Substitutionstherapie bei primären Immunmangelsyndromen, sek<strong>und</strong>ärer Hypogammaglobulinämie <strong>und</strong> rezidivierenden bakteriellen Infektionen bei CLL <strong>und</strong> multiplem Myelom,<br />
Kinder mit angeborenem AIDS <strong>und</strong> rezidivierenden Infektionen. Immunmodulation bei ITP bei Kindern oder Erwachsenen mit einem hohen Blutungsrisiko oder vor chirurgischen Eingriffen zur Korrektur der<br />
Thrombozytenzahl, Guillain-Barré-Syndrom <strong>und</strong> Kawasaki-Syndrom. Allogene Knochenmarktransplantation. Art der Anwendung, Dosierung: Intratect® wird intravenös verabreicht. Dosierung <strong>und</strong> Intervalle der<br />
Infusionen richten sich nach der Indikation. Gegenanzeigen: Überempfi ndlichkeit gegen jegliche Bestandteile des Präparates. Überempfi ndlichkeit gegen homologe Immunglobuline, insbesondere in den sehr<br />
seltenen Fällen von IgA-Mangel, wenn der Patient Antikörper gegen IgA aufweist. Spezielle Hinweise: Bestimmte schwere unerwünschte Nebenwirkungen können im Zusammenhang mit der Infusionsgeschwindigkeit<br />
stehen. Es ist die in der Gebrauchsinformation beschriebene Infusionsgeschwindigkeit zu beachten. Die Patienten müssen während der gesamten Dauer der Infusion kontrolliert <strong>und</strong> auf Symptome unerwünschter<br />
Wirkungen beobachtet werden. Bestimmte unerwünschte Nebenwirkungen können bei einer hohen Infusionsgeschwindigkeit häufi ger auftreten, bei Patienten mit Hypo- oder Agammaglobulinämie<br />
mit oder ohne IgA-Mangel, bei Patienten, die zum ersten Mal Immunglobulin vom Menschen erhalten oder, in seltenen Fällen, bei einem Wechsel des Immunglobulin-Präparates oder nach einer längeren Behandlungspause.<br />
Nebenwirkungen: Gelegentlich können Schüttelfrost, Kopfschmerzen, Fieber, Übelkeit <strong>und</strong> Erbrechen, allergische Reaktionen, niedriger Blutdruck, Gelenkschmerzen <strong>und</strong> leichte Rückenschmerzen.<br />
Selten: plötzlicher Blutdruckabfall, vorrübergehende Hautreaktionen, Anstieg des Serumkreatinin-Spiegels, akutes Nierenversagen, thromboembolische Komplikationen. In Einzelfällen: anaphylaktischer Schock,<br />
reversible aseptische Meningitis, reversible hämolytische Anämie/Hämolyse. Wechselwirkungen: Die Gabe von Immunglobulin kann <strong>für</strong> eine Dauer von mindestens 6 Wochen <strong>und</strong> bis zu 3 Monaten die Wirksamkeit<br />
von attenuierten Lebendimpfstoffen wie Masern-, Röteln-, Mumps- <strong>und</strong> Windpockenimpfstoffen beeinträchtigen. Nach der Gabe dieses Präparates ist vor der Impfung mit attenuierten Lebendimpfstoffen<br />
eine Wartezeit von 3 Monaten einzuhalten. Bei Masernimpfung kann diese Beeinträchtigung bis zu einem Jahr fortbestehen. Daher sollte bei Patienten, die Masernimpfstoff erhalten, der Antikörperstatus überprüft<br />
werden. Handelsformen: Gebrauchsfertige Lösung zur intravenösen Infusion in Durchstichfl aschen aus Glas zu 20 ml (1,0 g), 50 ml (2,5 g), 100 ml (5,0 g) <strong>und</strong> 200 ml (10,0 g).<br />
Biotest Pharma GmbH · Postfach 10 20 40 · D-63266 Dreieich · www.biotest.de<br />
Intratect_DGN.260706.indd 1 01.08.2006 11:41:20 Uhr