29.11.2012 Views

Programm A4 - Österreichische Gesellschaft für Allergologie und ...

Programm A4 - Österreichische Gesellschaft für Allergologie und ...

Programm A4 - Österreichische Gesellschaft für Allergologie und ...

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

<strong>Österreichische</strong> <strong>Gesellschaft</strong> <strong>für</strong> <strong>Allergologie</strong> <strong>und</strong> Immunologie<br />

&<br />

Deutsche <strong>Gesellschaft</strong> <strong>für</strong> Immunologie<br />

JOINT ANNUAL MEETING<br />

OF IMMUNOLOGY<br />

OF THE<br />

AUSTRIAN AND GERMAN SOCIETIES<br />

Lecture Centre of the Vienna General Hospital<br />

Vienna, Austria<br />

Wednesday, September 3 – Saturday, September 6, 2008<br />

Final <strong>Programm</strong>e<br />

www.medacad.org/oegai2008


ALLERGIE LAUF<br />

Sonntag, 7. September 2008<br />

Schlosspark Schönbrunn<br />

Hiermit laden wir Sie ganz herzlich dazu ein, im Anschluss an den Kongress<br />

„Joint Annual Meeting of Immunology, Wien, 3.-6. September 2008“, am<br />

ALLERGIE LAUF am Sonntag, 7. September 2008<br />

im SCHLOSSPARK SCHÖNBRUNN,<br />

einer der schönsten Parkanlagen Wiens, teilzunehmen.<br />

Nach dem Startschuss von Nobelpreisträger Peter Doherty geht es durch den Schlosspark Schönbrunn,<br />

durch Alleen mit barocker Gartenbaukunst, <strong>und</strong> vorbei am Schloss Schönbrunn, einem der bedeutendsten<br />

Kulturdenkmäler Österreichs, einst bewohnt von Kaiserin Sissi <strong>und</strong> heute ein beliebtes Ausflugsziel vieler<br />

Wiener <strong>und</strong> Wienbesucher.<br />

Sie können unter verschiedenen Distanzen wählen <strong>und</strong> auch im Team laufen. Das Tempo bleibt Ihnen<br />

überlassen: gemütlich oder mit sportlichem Ehrgeiz, dazu wird es eine exakte elektronische Zeitmessung<br />

geben. Ob Kongressteilnehmer oder nicht - es sind alle eingeladen, mit zu laufen.<br />

Im Anschluss an den Lauf folgen als Krönung des Tages <strong>und</strong> als Belohnung <strong>für</strong> Ihren sportlichen Einsatz<br />

<strong>und</strong> das tüchtige anfeuern Ihrer Fans, die After Running Party, die Siegerehrung, eine Tombola, ein<br />

Buffet reich an köstlichen typisch österreichischen Gerichten, <strong>und</strong> eine Musikshow. Es unterhalten<br />

Sie Harry Sonnek <strong>und</strong> der legendäre Dave Dee, der mit seinen besten Songs aus den 60ern aus London<br />

zu uns kommen wird <strong>und</strong> <strong>für</strong> die richtige Partystimmung sorgen wird. Zur After Running Party sind alle<br />

Läufer <strong>und</strong> deren Begleiter ganz herzlich eingeladen.<br />

Bitte nutzen Sie die Möglichkeit der Online-Anmeldung auf www.medacad.org/oegai2008 unter „Allergy<br />

Run“ sobald als möglich, damit Sie sich Ihr, in der Gebühr inkludiertes, Erinnerungs- T-Shirt in der<br />

richtigen Größe sichern.<br />

Auf der Homepage finden Sie auch alle mit dem Lauf verb<strong>und</strong>enen Informationen, sowie den vorläufigen<br />

Streckenplan.<br />

Wir freuen uns auf zahlreiche Anmeldungen!<br />

www.b<strong>und</strong>esgaerten.at


<strong>Österreichische</strong> <strong>Gesellschaft</strong> <strong>für</strong> <strong>Allergologie</strong> <strong>und</strong> Immunologie<br />

&<br />

Deutsche <strong>Gesellschaft</strong> <strong>für</strong> Immunologie<br />

JOINT ANNUAL MEETING<br />

OF IMMUNOLOGY<br />

OF THE<br />

AUSTRIAN AND GERMAN SOCIETIES<br />

Lecture Centre of the Vienna General Hospital<br />

Vienna, Austria<br />

Wednesday, September 3 – Saturday, September 6, 2008<br />

Final <strong>Programm</strong>e<br />

www.medacad.org/oegai2008


Table of Contents<br />

General<br />

Patronage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2<br />

Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2<br />

Welcome Addresses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3<br />

Committees – Board – Organisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5<br />

<strong>Programm</strong>e at a Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6<br />

Scientific <strong>Programm</strong>e<br />

- Wednesday, September 3, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8<br />

- Thursday, September 4, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9<br />

- Friday, September 5, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15<br />

- Saturday, September 6, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20<br />

Poster Viewing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25<br />

Business Meetings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26<br />

Satellite Lunch Symposia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27<br />

Information on Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28<br />

Information for Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29<br />

Information<br />

Congress Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30<br />

Registration Fees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32<br />

General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33<br />

Venue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35<br />

Social Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37<br />

Undergro<strong>und</strong> Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38<br />

City Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39<br />

Exhibition<br />

Exhibition – General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40<br />

List of Sponsors, Exhibitors and Advertisers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41<br />

1


Patronage<br />

Under the Patronage of<br />

Dr. Alfred Gusenbauer<br />

Federal Chancellor of the Federal Republic of Austria<br />

Dr. Johannes Hahn<br />

Federal Minister for Science and Research<br />

Dr. Andrea Kdolsky<br />

Federal Minister for Health, Family and Youth<br />

Mag. Sonja Wehsely<br />

Executive City Councillor for Public Health and Social Affairs<br />

Acknowledgements<br />

The Joint Annual Meeting of Immunology gratefully acknowledges the support of the following<br />

institutions, companies and organisations (list correct as per date of printing):<br />

2


Welcoming Addresses<br />

Unquestionably a high level of health care is the core element of our modern<br />

welfare system as we know it. It is therefore our duty as politicians to secure<br />

the basis for its long-term financial stability. Furthermore, we must create an<br />

institutional and legal framework to guarantee universal and non-discriminatory<br />

access to all forms of treatment. Nobody should be excluded or left<br />

behind. Only <strong>und</strong>er these conditions can health-care professionals fulfil their<br />

essential duty and live up to their oath i.e. helping people.<br />

Public opinion polls show the high satisfaction of Austrians with our national<br />

health care system. But no society can satisfy itself with self appreciation. Many challenges lie<br />

ahead of us. Some are institutional, financial, others are scientific. This congress will help to promote<br />

knowledge and hopefully inspire all working in your field.<br />

On behalf of the Austrian government it is my pleasure to welcome you here in Austria and in<br />

particular at this “Joint Annual Meeting of Immunology”.<br />

Dr. Alfred Gusenbauer<br />

Federal Chancellor of the Federal Republic of Austria<br />

More than 1000 participants at the „Joint Annual Meeting of lmmunology"<br />

give invigorating proof of the importance and international reputation of the<br />

Societies of Allergology and Immunology in Austria and Germany on the one<br />

hand and the Vienna Medical Academy in the fields of education/research as<br />

well as conference and association management – an organisation dedicated<br />

to serving the needs of the medical non-profit community - on the other. As<br />

minister of Science and Research it is good news for me that international<br />

experts are discussing such pressing topics as vaccination, infection and<br />

allergy just now in Austria. That means new incentives for the Scientific Community<br />

especially in our country and the opportunity to expand international networking. These<br />

issues are of great relevance for nearly all of us and the expectations are very high, if you only think<br />

of tumor immunology for example. May the meeting be a successful one with impressing results<br />

and congratulations on bringing together university professors of international reputation in this<br />

field in Vienna for the first time. In this way the meeting is a great recognition of Vienna as an important<br />

medical research place.<br />

Dr. Johannes Hahn<br />

Federal Minister for Science and Research<br />

3


Welcoming Addresses<br />

Dear colleagues and scientific friends,<br />

It is our great pleasure to welcome you to the Joint Annual Meeting of the Austrian and the German<br />

Societies of Immunology in Vienna.<br />

The annual conferences of our societies allow for an exchange of thoughts and information on cutting<br />

edge developments taking place in the immunological laboratories worldwide. The format of<br />

a joint annual conference allows for an expansion of this exchange into a neighbouring country<br />

and likewise fosters new and/or permits to renew longstanding scientific and social relationships.<br />

With this meeting we are aiming to delineate the latest progress in our field, focusing on matters<br />

arising not only in basic innate and adaptive immunity, but also clinical immunology including<br />

novel therapeutic approaches. The scientific committee has invited outstanding scientists to present<br />

their thinking and to summarize data on their advances in plenary sessions and introductions<br />

to workshops. Within workshops and during the poster sessions, there will be ample opportunity<br />

especially for students and postdoctoral fellows to present their newest research results and thus<br />

a broad array of work which is performed in the realm of the hosting societies and beyond.<br />

We have made all efforts to create a scientific program that meets your expectations. In addition<br />

you shall enjoy Vienna´s ambience and hospitality, the unique culture and spirit which so few<br />

other cities have to offer.<br />

With best wishes for a scientifically exciting and<br />

stimulating meeting and<br />

mit herzlichen Grüßen,<br />

Yours<br />

Stefan Meuer & Josef Smolen<br />

4


Committees – Board – Organisation<br />

Congress Committee<br />

Stefan C.W. Meuer Josef Smolen<br />

Andreas Radbruch Marcus Säemann<br />

Reinhold E. Schmidt<br />

Local Organising Committee<br />

Irmgard Förster Marcus Säemann<br />

Beatrix Grubeck-Loebenstein Reinhold Schmidt<br />

Erika Jensen-Jarolim Josef Smolen<br />

Stefan C.W. Meuer Hannes Stockinger<br />

Winfried Pickl Rudolf Valenta<br />

Andreas Radbruch Gerhard Zlabinger<br />

ÖGAI Executive Committee<br />

Josef Smolen (President) Gernot Achatz (Board Member)<br />

Rudolf Valenta (President Elect) Hans-Peter Brezinsek (Board Member)<br />

Beatrix Grubeck-Loebenstein (Past President) Roswitha Gruber-Sgonc (Board Member)<br />

Marcus Säemann (Secretary General) Erika Jensen-Jarolim (Board Member)<br />

Winfried Pickl (Deputy Secretary) Johannes Stöckl (Board Member)<br />

Tamara Kopp (Secretary Protocol) Martin Thurnher (Board Member)<br />

Barbara Bohle (Treasurer) Othmar Förster (Honorary President)<br />

DGfI Executive Committee<br />

Stefan C.W. Meuer (President) Reinhold Förster (Board Member)<br />

Andreas Radbruch (President Elect) Stefan H. E. Kaufmann (Board Member)<br />

Reinhold E. Schmidt (Past President) Heidrun Moll (Board Member)<br />

Werner Solbach (Secretary General) Yvonne Samstag (Board Member)<br />

Christian Bogdan (Board Member) Burkhart Schraven (Board Member)<br />

Barbara Bröker (Board Member) Hans Dieter Volk (Board Member)<br />

Stefan Ehlers (Board Member)<br />

Irmgard Förster (Board Member)<br />

Hans-Martin Jäck (Board Member)<br />

Conference Organisation, Abstract Management, Sponsoring<br />

Vienna Medical Academy<br />

Ms. Marieke Hodel<br />

Alser Strasse 4, 1090 Vienna, Austria<br />

Phone: +43 1 405 1383-10; Fax: +43 1 407 8274<br />

E-mail: oegai2008@medacad.org<br />

Exhibition Management Hotel Accomodation<br />

Medizinische Ausstellungs- <strong>und</strong> Mondial Congress & Events<br />

Werbegesellschaft MAW Operngasse 20b<br />

Freyung 6 1040 Vienna<br />

A-1010 Vienna, Austria Phone: +43 1 58804-0<br />

Phone: +43 1 536 630 Fax: +43 1 58804-185<br />

Fax: +43 1 535 60 16<br />

E-mail: maw@media.co.at<br />

Email: oegai2008@mondial-congress.com<br />

Congress Venue<br />

Lecture Centre of the Vienna General Hospital<br />

(Allgemeines Krankenhaus - AKH)<br />

Währinger Gürtel 18-20<br />

1090 Vienna, Austria<br />

5


<strong>Programm</strong>e at a Glance<br />

Wednesday, September 3, 2008<br />

Time Lecture Hall 1<br />

Welcome and Opening<br />

Stefan Meuer, President DGfI<br />

Josef Smolen, President ÖGAI<br />

15.00 –<br />

15.10<br />

Karl Landsteiner (1868-1943) - An Austrian Immuno-Pathologist (G. Schmidt-Wyklicky)<br />

Awarding of the Landsteiner Price of the DGfI to Max Cooper<br />

Awarding of the Landsteiner Medal of the ÖGAI to Ron Germain<br />

Vienna Philharmonic<br />

Keynote Lecture: Nobel Laureate Peter Doherty<br />

Vienna Philharmonic<br />

Opening by Wolfgang Schütz (Rector of the Medical University of Vienna)<br />

15.10 –<br />

15.25<br />

15.25 –<br />

15.45<br />

15.45 –<br />

16.05<br />

16.05 –<br />

16.20<br />

16.20 –<br />

16.50<br />

16.50 –<br />

17.00<br />

17.00 –<br />

17.15<br />

Followed by Welcome Drinks<br />

Thursday, September 4, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

Parallel Symposium 1:<br />

08.15 – Parallel Symposium 1:<br />

Parallel Symposium 1:<br />

Innate Immunity: Antigen-Presenting-<br />

09.30 T-Cell Signaling<br />

Tumor Immunology<br />

Cells<br />

Break & Poster Viewing<br />

Innate Immunity: Antigen-Presenting<br />

Cells<br />

T-Lymphocytes I Autoimmunity I Tumor Immunology Immunomodulation<br />

09.30 –<br />

10.30<br />

10.30 –<br />

12.15<br />

Satellite Lunch Symposium:<br />

B cell: Promising target in autoimmune<br />

diseases (Roche)<br />

T-Lymphocytes II Vaccines & Adjuvants Signal Transduction NK cells Veterinary Immunology<br />

12.15 –<br />

13.45<br />

14.00 –<br />

15.30<br />

15.30 –<br />

Break & Poster Viewing<br />

16.30<br />

16.45 – Parallel Symposium 2:<br />

Parallel Symposium 2:<br />

Parallel Symposium 2:<br />

18.00 Vaccination<br />

In vivo imaging<br />

Immunomodulation<br />

19.00 Welcome Reception at the Vienna City Hall<br />

6<br />

Plenary Session Parallel Symposium Workshops Satellite Lunch Symposium


<strong>Programm</strong>e at a Glance<br />

Friday, September 5, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

08.15 – Parallel Symposium 1:<br />

Parallel Symposium 1:<br />

Parallel Symposium 1:<br />

09.30 Innate Immunity: Regulation<br />

Mucosal Inflammation<br />

Transplantation<br />

09.30 –<br />

Break & Poster Viewing<br />

10.30<br />

10.30 –<br />

Pattern Recognition Receptors &<br />

Allergy I Regulatory Lymphocytes I Alloimmunity & Tolerance<br />

Innate Immunity: Regulation<br />

12.15<br />

Myeloid Cells<br />

12.15 –<br />

Satellite Lunch Symposium:<br />

13.00<br />

Immune modulation with intravenous<br />

13.00 – Drittmittelförderung der DFG: Kriterien immunoglobulin: the established and<br />

13.45 <strong>für</strong> eine erfolgreiche Antragstellung the advances (Octapharma)<br />

14.00 –<br />

Infection I Allergy II Regulatory Lymphocytes II Mucosal Immunity B-Lymphocytes<br />

15.30<br />

15.30 –<br />

Break & Poster Viewing<br />

16.30<br />

16.45 – Parallel Symposium 2:<br />

Parallel Symposium 2:<br />

Parallel Symposium 2:<br />

18.00 Infection<br />

Adaptive Immunity: Regulation Adaptive Immunity: B-Cells<br />

18.00 –<br />

General Assembly DGfI<br />

19.30<br />

19.30 Departure with buses to the Viennese “Heuriger” Fuhrgassl-Huber<br />

Saturday, September 6, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

08.45 – Parallel Symposium 1:<br />

Parallel Symposium 1:<br />

Parallel Symposium 1:<br />

10.00 Autoimmunity<br />

Inflammation<br />

Allergy<br />

10.00 –<br />

Break<br />

10.30<br />

10.30 –<br />

Cytokines, Chemokines & their<br />

Satellite Lunch Symposium:<br />

Autoimmunity II Infection II Complement System<br />

12.15<br />

receptors<br />

Vom rekombinanten Allergen zu<br />

12.15 –<br />

neuen Allergietherapien (Phadia)<br />

12.45<br />

Break<br />

12.45 –<br />

Break<br />

13.00<br />

13.00 – Klinische Fälle aus der <strong>Allergologie</strong>:<br />

13.45 Wie hätten Sie entschieden?<br />

14.00 –<br />

Best Poster Awards<br />

14.30<br />

15.00 General Assembly ÖGAI<br />

7<br />

Plenary Session Parallel Symposium Workshops Satellite Lunch Symposium


Scientific <strong>Programm</strong>e – Wednesday, September 3, 2008 8<br />

Time Lecture Hall 1<br />

15.00<br />

-<br />

15.10<br />

15.10<br />

-<br />

15.25<br />

15.25<br />

-<br />

15.45<br />

15.45<br />

-<br />

16.05<br />

16.05<br />

-<br />

16.20<br />

16.20<br />

-<br />

16.50<br />

16.50<br />

-<br />

17.00<br />

17.00<br />

-<br />

17.15<br />

Welcome<br />

Chair: S. Meuer, J. Smolen<br />

Welcoming addresses by<br />

Stefan Meuer, President DGfI<br />

Josef Smolen, President ÖGAI<br />

Karl Landsteiner (1868-1943) - An Austrian Immuno-Pathologist<br />

Gabriela Schmidt-Wyklicky<br />

Awarding of the Landsteiner Price of the DGfI to Max Cooper<br />

Laudatio: Andreas Radbruch<br />

Award Lecture: Max Cooper<br />

Awarding of the Landsteiner Medal of the ÖGAI to Ron Germain<br />

Laudatio: Clemens Scheinecker<br />

Award Lecture: Ron Germain<br />

Rainer Honeck, Concert Master of the The Vienna Philharmonic Orchestra: J.S. Bach<br />

Keynote Lecture:<br />

Nobel laureate Peter Doherty<br />

Rainer Honeck, Concert Master of the Vienna Philharmonic Orchestra: F. Kreisler<br />

Opening by Wolfgang Schütz (Rector of the Medical University of Vienna)<br />

17.15 Welcome Drinks


Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 9<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />

08.15<br />

-<br />

09.30<br />

09.30<br />

-<br />

10.30<br />

Parallel Symposium 1:<br />

T-Cell Signaling<br />

Chair: W. Pickl, D. Kabelitz<br />

Molecular determinants of Inside-out<br />

signaling in T-cells<br />

B. Schraven<br />

From T cell activation signals to signaling<br />

control of anti-cancer immunity<br />

J. Penninger<br />

Deciphering TCR ligand discrimination by<br />

combining experiments, computer<br />

modeling, and predictive simulations<br />

R. Germain<br />

Parallel Symposium 1:<br />

Innate Immunity: Antigen-Presenting-<br />

Cells<br />

Chair: G. Stingl, B. Broeker<br />

DC dependent maintenance of peripheral<br />

regulatory T-cells<br />

S. Beissert<br />

Role of antimicrobial peptides in triggering<br />

autoimmunity<br />

M. Gilliet<br />

TLR-activated dendritic cells as effector<br />

cells of the immune response<br />

G. Stingl<br />

Coffee Break / Poster Viewing / Exhibition<br />

Parallel Symposium 1:<br />

Tumor Immunology<br />

Chair: E. Jensen-Jarolim, G. Riethmüller<br />

Human Self/Tumor Antigens and Tumor<br />

Immunosurveillance<br />

O.J. Finn<br />

The immune response to sporadic cancer<br />

T. Blankenstein<br />

Development of DNA vaccination strategies<br />

for pediatric cancers<br />

H.N. Lode


Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 10<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

10.30<br />

-<br />

12.15<br />

T-Lymphocytes I<br />

Chair: G. Schütz,<br />

H. Wolf<br />

1. Increased Th17 and<br />

decreased CD4+FoxP3+<br />

T regulatory cells in third<br />

trimester pregnancies<br />

with pre-eclampsia<br />

B. Santner-Nanan,<br />

M. Peek, L. Richarts,<br />

R. Khanam, E. Zhu, B.<br />

Fazekas de St. Groth,<br />

R. K. Nanan<br />

2. Blockade of inducible<br />

costimulator (ICOS) inhibits<br />

accumulation of<br />

polyfunctional<br />

Th1/Th17cCells and prevents<br />

autoimmune arthritis<br />

O. Frey, J. Meisel,<br />

L. Bruns, A. Hutloff,<br />

L. Morawietz, T. Kamradt<br />

3. IRF4 is essential for<br />

IL-21-mediated induction,<br />

amplification and<br />

stabilization of the Th17<br />

phenotype<br />

M. Huber, A. Brüstle,<br />

A. Guralnik, A. Mahiny,<br />

E. von Löw, M. Lohoff<br />

4. Acid sphingomyelinase<br />

is a critical regulator<br />

of cytotoxic granule<br />

secretion by primary T<br />

lymphocytes<br />

J. Herz, J. Pardo,<br />

H. Kashkar,<br />

M. Schramm,<br />

E. Kuzmenkina, E. Bos,<br />

K. Wiegmann,<br />

R. Wallich, P. J. Peters,<br />

S. Herzig, E. Schmelzer,<br />

M. Krönke, M. M. Simon,<br />

O. Utermöhlen<br />

5. Adenosine regulates<br />

CD8 T cell priming by inhibition<br />

of membraneproximal<br />

T cell receptor<br />

signaling<br />

D. Stabenow,<br />

C. Linnemann,<br />

F. A. Schildberg,<br />

A. Schurich,<br />

S. I. Hegenbarth,<br />

L. Diehl, E. Endl,<br />

S. Lacher, C. E. Müller,<br />

J. Frey, L. Simeoni,<br />

L. Simeoni, B. Schraven,<br />

P. A. Knolle<br />

6. pSMAC formation in<br />

human peripheral blood<br />

T-cells requires localization<br />

of the actin-b<strong>und</strong>ling<br />

protein L-plastin to the<br />

immunological synapse<br />

G. Wabnitz, P. Lohneis,<br />

H. Kirchgessner,<br />

Y. Samstag<br />

Autoimmunity I<br />

Chair: H. Strobl,<br />

G. Beilhack<br />

9. The role of B cells in<br />

tissue draining lymphnodes<br />

for the development<br />

of collagen<br />

induced arthritis (CIA)<br />

C. Scheinecker,<br />

A. Rapp, M. Bonelli,<br />

A. Savitskaya,<br />

J. S. Smolen<br />

10. T helper cells only induce<br />

acute inflammation<br />

but B cells are necessary<br />

for the induction of<br />

chronic Antigen-induced<br />

Arthritis<br />

M. Janke, T. Hohnstein,<br />

L. Morawietz,<br />

A. Scheffold<br />

11. Crucial role of CCR4<br />

in the development of<br />

experimental CNS autoimmune<br />

disease by<br />

modulation of Treg cell<br />

compartimentalization<br />

J. Alferink, D. M. Otte,<br />

K. Poppensieker,<br />

Ö. Yilmaz, A. Mildner,<br />

M. Prinz, W. Maier,<br />

A. Zimmer<br />

12. Antigen-specific<br />

TGF -induced Treg suppress<br />

Th17-mediated<br />

autoimmune disease<br />

E. N. Huter,<br />

G. H. Stummvoll,<br />

E. M. Shevach<br />

13. The pathogenic role<br />

of HnRNP-A2 in Pristane-induced<br />

arthritis<br />

M. H. Hoffmann, C.<br />

Baumann, B. Meyer,<br />

G. Steiner<br />

14. The autoimmune regulator<br />

Roquin-a cofactor<br />

for miRNA function?<br />

E. Glasmacher,<br />

K. P. Höfig, E. Kremmer,<br />

V. Heissmeyer<br />

Tumor Immunology<br />

Chair: J. Singer,<br />

T. Weichhart<br />

17. Higher avidity of<br />

TCR-gene-modified T<br />

cells by using parts of<br />

the murine constant TCR<br />

regions<br />

D. Sommermeyer,<br />

W. Uckert<br />

18. Reprogramming T<br />

cells to become MHC independent<br />

- electroporation<br />

of RNA encoding<br />

chimeric antigen receptors<br />

N. Schaft, T. Sch<strong>und</strong>er,<br />

C. Krug, S. Reuter,<br />

D. Kosmides, H. Abken,<br />

M. Kershaw,<br />

E. Kämpgen, G. Schuler,<br />

J. Dörrie<br />

19. Memory CD8+ T-cell<br />

mediated tumor rejection<br />

is impaired in NKG2Ddysfunctional<br />

mice<br />

M. C. Banerjea,<br />

D. Sigurdardottir,<br />

B. Pömmerl,<br />

H. Rammensee,<br />

A. Steinle<br />

20. Rejection of established<br />

cancer: Lack of<br />

IFN- , TNF- and Fas-ligand<br />

but not perforin by<br />

effector CD8+ T cells allows<br />

cancer to progress<br />

J. J. Listopad,<br />

G. Willimsky,<br />

B. Silkenstedt,<br />

T. Kammertöns,<br />

T. Blankenstein<br />

21. Defects of the antigen<br />

processing machinery<br />

leading to T cell<br />

resistance of melanoma<br />

cells<br />

M. Keller, F. Ebstein,<br />

A. Paschen, E. Bürger,<br />

D. Schadendorf,<br />

P. M. Kloetzel,<br />

U. Seifert<br />

22. Tumor-specific T<br />

helper cells regulate<br />

tumor dormancy or<br />

progress multistage carcinogenesis<br />

through T<br />

cell cytokines<br />

H. Braumueller,<br />

T. Wieder, N. Bauer,<br />

M. Rocken<br />

Immunomodulation<br />

Chair: K. Loser,<br />

W. Berger<br />

25. Regulation of homing<br />

receptor expression in<br />

CD4 + T cells<br />

B. A. Ratsch, C. Doebis,<br />

S. Jennrich, S. Floess,<br />

A. Hamann, U. Syrbe<br />

26. Regulated release<br />

and functional modulation<br />

of junctional adhesion<br />

molecule A by<br />

disintegrin metalloproteinases<br />

J. Pruessmeyer,<br />

R. Koenen, L. Fraemohs,<br />

O. Soehnlein, C. Weber,<br />

A. Ludwig<br />

27. Ontogeny of Langerhans<br />

cells in prenatal<br />

human skin<br />

C. Schuster, C. Vaculik,<br />

C. Fiala, W. Eppel,<br />

S. Meindl, M. Imhof,<br />

A. Elbe-Bürger<br />

28. Requirement of<br />

CCL17 for progression<br />

of atopic dermatitis and<br />

contact hypersensitivity<br />

in mice<br />

S. Stutte, N. Gerbitzki,<br />

I. Förster<br />

29. Acid sphingomyelinase<br />

is required for efficient<br />

phago-lysosomal<br />

fusion<br />

M. Schramm, U. Karow,<br />

A. Haas, M. Krönke,<br />

O. Utermöhlen<br />

30. Phenotypic and molecular<br />

analysis of an<br />

HLA Class II deficient<br />

patient reveals a homozygous<br />

nonsense<br />

mutation in the CIITA<br />

gene at amino acid position<br />

381<br />

K. G. Schmetterer,<br />

M. G. Seidel,<br />

U. Körmöczi,<br />

K. Schwarz, S. Matthes-<br />

Martin, P. Steinberger,<br />

W. F. Pickl<br />

Innate Immunity: Antigen-Presenting<br />

Cells<br />

Chair: N. Romani,<br />

H. Schild<br />

33. Targeting of<br />

Haemagglutinin antigen<br />

to C-type Lectins on<br />

human Dendritic Cells<br />

elicits different T cell responses<br />

in vitro<br />

G. F. Heidkamp,<br />

F. Nimmerjahn,<br />

A. Piperno, H. Zebroski,<br />

R. M. Steinman,<br />

M. C. Nussenzweig,<br />

D. Dudziak<br />

34. PPARgamma enhances<br />

uptake and<br />

cross-presentation of<br />

soluble antigen in dendritic<br />

cells<br />

S. Hucke, J. Floßdorf,<br />

I. Dani, D. Thimm,<br />

A. Kautz, C. Kurts,<br />

P. Knolle, L. Klotz,<br />

S. Burgdorf<br />

35. Genomic RNA of<br />

human rhinovirus - a<br />

”semi-danger-signal” for<br />

dendritic cells<br />

C. Schrauf,<br />

S. Kirchberger,<br />

O. Majdic, J. Seipelt,<br />

J. Stöckl<br />

36. Antagonism between<br />

GATA-1 and vitamin D3<br />

receptor in myelopoisis<br />

and dendritic cell subset<br />

differentiation<br />

S. Taschner-Mandl,<br />

F. Göbel, M. Kumerz,<br />

J. Jurkin, C. Vaculik,<br />

S. Richter, C.<br />

Bieglmayer,<br />

A. Elbe-Bürger,<br />

H. Strobl<br />

37. Function of hypoxiainducible<br />

factor (HIF)-1<br />

in dendritic cells<br />

T. Köhler,<br />

R. S. Johnson,<br />

H. Weighardt, I. Förster<br />

38. Distinct mechanism<br />

of antigen routing and<br />

cross-presentation in<br />

LSEC<br />

A. K. Schurich,<br />

J. Böttcher, S. Burgdorf,<br />

P. Penzler,<br />

S. Hegenbarth,<br />

D. Stabenow, A. Dolf,<br />

E. Endl, C. Kurts,<br />

P. A. Knolle


Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 (continued) 11<br />

Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

7. The effect of thymectomy<br />

in early childhood<br />

on the naive T cell compartment<br />

in later life<br />

M. Prelog, M. Keller,<br />

R. Geiger, A. Brandstaetter,<br />

R. Würzner,<br />

B. Grubeck-Loebenstein,<br />

L. B. Zimmerhackl<br />

8. Clonal evolution of the<br />

effector T cell repertoire<br />

D. Zehn, M. J. Bevan<br />

Time Lecture Hall 1<br />

12.15<br />

-<br />

13.45<br />

15. OSCAR, a key costimulation<br />

molecule for<br />

osteoclasts, is induced<br />

in patients with rheumatoid<br />

arthritis<br />

S. Herman, G. Krönke,<br />

R. Müller, J. Zwerina,<br />

K. Redlich, G. Schett<br />

16. Imaging immuneneuronal<br />

interactions in<br />

experimental auto -<br />

immune encephalo -<br />

myelitis using intravital<br />

two- photon microscopy<br />

V. Siffrin, J. Herz,<br />

T. Leuenberger,<br />

A. U. Brandt,<br />

H. Radbruch, R. Niesner,<br />

C. Infante-Duarte,<br />

F. Zipp<br />

Satellite Lunch Symposium - Roche<br />

B cell: Promising target in autoimmune diseases<br />

Chair: J. Smolen<br />

The biology of the B cell in autoimmune diseases<br />

A. Radbruch<br />

Clinical experiences with B cell therapies<br />

T. Dörner<br />

Safety: Experiences with Rituximab<br />

H-P. Brezinsek<br />

23. Identification of<br />

tumor antigens using antibodies<br />

induced by dendritic<br />

cell (DC) based<br />

vaccines<br />

J. Leitner, A. Stift,<br />

J. Friedl, R. Pfranger,<br />

P. Steinberger,<br />

K. Pfistershammer<br />

24. Serological relationship<br />

between cutaneous<br />

human papillomavirus<br />

types 5, 8 and 92<br />

A. Handisurya,<br />

C. Schellenbacher,<br />

R. Gambhira,<br />

S. Shafti-Keramat,<br />

O. Forsl<strong>und</strong>, M. Favre,<br />

R. Kirnbauer<br />

31. Different mechanisms<br />

of immunosuppression<br />

caused by<br />

Cyclosporine A (CsA)<br />

and FK506<br />

T. Giese, C. Sommerer,<br />

C. Jacobi, M. Zeier,<br />

S. Meuer<br />

32. Identification of three<br />

novel genes as<br />

biomarker for monitoring<br />

anti-TGFbeta therapy<br />

S. Classen, C. Muth,<br />

D. Eggle, M. Beyer,<br />

T. Zander,<br />

A. Staratschek-Jox,<br />

J. L. Schultze<br />

39. Skin dendritic cells<br />

present lipid antigens to<br />

natural killer T cells<br />

P. Stoitzner,<br />

I. F. Hermans,<br />

N. Romani


Scientific <strong>Programm</strong>e – Thursday, September 4, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

14.00<br />

-<br />

15.30<br />

T-Lymphocytes II<br />

Chair: M. Lohoff,<br />

A. Thiel<br />

40. Stability and flexibility<br />

of CD4 T cell differentiation<br />

programs in vitro<br />

and in vivo<br />

A. N. Hegazy,<br />

H. Hengartner,<br />

R. M. Zinkernagel,<br />

A. Radbruch,<br />

M. Löhning<br />

41. On the role of<br />

adipokines in Th2 lymphocyte<br />

polarization<br />

A. Batra, B. Okur, J.<br />

Ihbe, T. Stroh,<br />

R. Glauben, I. Fedke,<br />

M. Zeitz, B. Siegm<strong>und</strong><br />

42. In vivo generated<br />

Th17 cells have a stable<br />

memory for IL-17 expression<br />

M. H. Lexberg,<br />

I. Albrecht, A. Förster,<br />

A. Richter, A. Radbruch,<br />

H. D. Chang<br />

43. Role of HDAC in T<br />

helper cell development<br />

R. Glauben,<br />

E. Sonnenberg, I. Fedke,<br />

P. Mascagni, M. Zeitz,<br />

B. Siegm<strong>und</strong><br />

44. Human<br />

CD4 + CD25 + Foxp3 + regulatory<br />

T cells efficiently<br />

inhibit GvHD induction in<br />

a humanized mouse<br />

model<br />

C. Becker, J. Kubach,<br />

C. Taube, C. Becker,<br />

K. Michel, K. Reifenberg,<br />

H. Jonuleit<br />

45. Mathematical modeling<br />

of the diversity of the<br />

immunological synapse<br />

M. T. Figge,<br />

M. Meyer-Hermann<br />

Vaccines & Adjuvants<br />

Chair: B. Grubeck,<br />

S. Weiss<br />

48. Improvement of the<br />

Immunogenicity of a<br />

HIV-1 Clade C Candidate<br />

Vaccine increasing<br />

Gag, Pol, Nef and Env<br />

Specific T-Cell Responses<br />

J. Wild, J. Koestler,<br />

S. Bredl, K. Boeckl,<br />

R. Wagner<br />

49. Safety and immunogenicity<br />

in a phase I<br />

dose-escalation BPV-1<br />

VLP vaccine trial in<br />

horses<br />

R. Kirnbauer, S. Brandt,<br />

S. Shafti-Keramat,<br />

E. K. Hainisch<br />

50. Characterisation of<br />

effects on growth of<br />

Staphylococcus aureus<br />

mediated by specific<br />

IgGs<br />

B. Tosetti, E. Glowalla,<br />

M. Krönke, O. Krut<br />

51. Analysis of the<br />

mechanisms mediating<br />

dendritic cell-based vaccination<br />

against Leishmania<br />

major<br />

J. K. Schnitzer,<br />

C. Hambrecht,<br />

M. Fajardo-Moser,<br />

K. A. Remer,<br />

H. Moll<br />

52. Virus-like particles: A<br />

cell-free antigen-presenting<br />

platform modulating<br />

lymphocyte<br />

activation in vitro and in<br />

vivo<br />

H. J. Kueng, V. M. Leb,<br />

D. Haiderer, G. Raposo,<br />

C. Thery, S. V. Derdak,<br />

K. G. Schmetterer,<br />

A. Neunkirchner,<br />

C. Sillaber, B. Seed,<br />

W. F. Pickl<br />

53. Priming and boosting<br />

of melanA-specific T<br />

cells - in vitro studies on<br />

the importance of antigen-presentation<br />

density<br />

J. Dörrie, N. Schaft,<br />

V. Wellner, C. Wohn,<br />

T. Sch<strong>und</strong>er, I. Müller,<br />

E. Kämpgen, G. Schuler<br />

Signal Transduction<br />

Chair: T. Bürckstürmer,<br />

T. Stulnig<br />

56. Oxidation of cofilin<br />

mediates T cell hyporesponsiveness<br />

<strong>und</strong>er oxidative<br />

stress conditions<br />

M. Klemke, G. Wabnitz,<br />

F. Funke, B. Funk,<br />

H. Kirchgessner,<br />

Y. Samstag<br />

57. The orphan adapter<br />

protein SLY1 as a novel<br />

anti-apoptotic protein required<br />

for thymocyte development<br />

B. Reis, D. Finkenstaedt,<br />

D. K. Finlay,<br />

D. A. Cantrell, K. Pfeffer,<br />

S. Beer<br />

58. Micropatterning of<br />

CD4 in the live cell<br />

plasma membrane reveals<br />

novel binding<br />

mechanisms to Lck<br />

M. Schwarzenbacher,<br />

M. Kaltenbrunner,<br />

M. Brameshuber,<br />

C. Hesch, W. Paster,<br />

J. Weghuber, B. Heise,<br />

A. Sonnleitner, H. Stokkinger,<br />

G. J. Schütz<br />

59. Stat3 serine 727<br />

phosphorylation upon<br />

activated TLR binding<br />

promotes via<br />

MyD88/TRIF safekeeping<br />

of IL-1beta<br />

S. Dreher, F. Schmitz,<br />

R. Ferstl, S. Spiller,<br />

J. Marges, A. Heit, I. Förster,<br />

R. Lang, H. Wagner,<br />

C. J. Kirschning<br />

60. Carma1/Bcl10/Malt1<br />

Complexes Transmit<br />

ITAM-coupled NK Cell<br />

Receptor Signals for NF-<br />

B and MAPK Activation<br />

O. Groß, C. Grupp,<br />

C. Steinberg,<br />

S. Zimmermann,<br />

D. Strasser,<br />

N. Hannesschläger,<br />

W. Reindl, C. Peschel,<br />

A. Krug, J. Ruland<br />

61. Functional analysis<br />

of the riboflavin kinase<br />

and its role in TNF-induced<br />

signalling<br />

B. Yazdanpanah,<br />

C. Pongratz,<br />

K. Wiegmann,<br />

H. Kashkar, M. Krönke<br />

NK cells<br />

Chair: C. Watzl,<br />

M. Fischer<br />

64. The stress-inducible<br />

endogenous danger signals<br />

HSP70 and MICA<br />

synergistically activate<br />

the cytotoxic effector<br />

functions of human NK cells<br />

L. Elsner, P. F. Flügge,<br />

J. Lozano, V. Muppala,<br />

S. Y. Demiroglu,<br />

D. Malzahn, H. Bickeböller,<br />

G. Multhoff, L. Walter,<br />

R. Dressel<br />

65. Regulation of NK cell<br />

activity through extracellular<br />

HLA-B-Associated<br />

Transcript 3<br />

E. Pogge von Strandmann,<br />

V. Simhadri,<br />

K. S. Reiners,<br />

H. P. Hansen, A. Engert<br />

66. Natural killer cell’s<br />

activation by Immunomodulin<br />

for treatment<br />

strategy of<br />

recurrent genital herpes<br />

V. Garib, U. Djabborov,<br />

Y. Rasul-Zade<br />

67. Decision making in<br />

NK cells<br />

D. Urlaub, S. Mesecke,<br />

H. Busch, R. Eils,<br />

C. Watzl<br />

68. Natural killer cells are<br />

modulated in patients<br />

with neuroimmunologic<br />

disorders in response to<br />

treatment with intravenous<br />

immunoglobulin<br />

C. Jacobi, M. Claus,<br />

B. Wildemann,<br />

J. Römisch, C. Watzl,<br />

S. Meuer, T. Giese<br />

69. Myeloid-Derived<br />

“Suppressor” Cells express<br />

Rae-1 and activate<br />

NK cells<br />

A. Cerwenka,<br />

E. Schlecker, I. Galani,<br />

N. Nausch<br />

12<br />

Veterinary Immunology<br />

Chair: A. Saalmüller,<br />

M. Müller<br />

72. Charakterization of<br />

the chicken CD40-<br />

CD40L system unsing<br />

the RCAS retroviral gene<br />

transfer technology<br />

K. Schenk-Weibhauser,<br />

J. Young, B. Kaspers,<br />

S. Kothlow<br />

73. Analysis of potential<br />

antiviral MX activity in<br />

the chicken<br />

B. Schusser, N. Penski,<br />

A. Reuter, G. Kochs,<br />

P. Staeheli, B. Kaspers,<br />

S. Kothlow<br />

74. MHC typing in swine:<br />

SLA class I and class IIallele<br />

distribution in Austrian<br />

Large White,<br />

Landrace, and Pietrain<br />

breeding stocks<br />

S. E. Hammer,<br />

J. Deutsch,<br />

B. C. Rütgen, S. Groiß,<br />

W. Gerner,<br />

S. Müller, A. Saalmüller<br />

75. Porcine coccidiosis -<br />

adaptive immune response<br />

mechanisms<br />

against Isospora suis<br />

H. L. Worliczek,<br />

W. Gerner, A. Saalmüller,<br />

A. Joachim<br />

76. Potential diagnostic<br />

markers for subclinical<br />

endometritis in cows:<br />

TNF-alpha, IL-1 alpha,<br />

IL-1 beta, and IL-8<br />

C. Gabler, M. Drillich,<br />

C. Fischer, C. Holder,<br />

W. Heuwieser,<br />

R. Einspanier<br />

77. Toll-like receptor expression<br />

and bacterial<br />

strain dependent<br />

chemokine response in a<br />

primary bovine colonic<br />

epithelial cell culture<br />

model<br />

P. S. Bridger, M. Mohr,<br />

J. Fröhlich, H. Metcalfe,<br />

D. Werling, G. Baljer,<br />

C. Menge


Scientific <strong>Programm</strong>e – Thursday, September 4, 2008 (continued)<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

15.30<br />

-<br />

16.30<br />

46. The role of the zinc<br />

finger protein MAZR in<br />

CD4/CD8 cell fate decisions<br />

during thymocyte<br />

development<br />

S. Sakaguchi, I. Bilic,<br />

M. Hombauer,<br />

A. Schebesta,<br />

W. Ellmeier<br />

47. 2D-DIGE analysis of<br />

enriched secretory lysosomes<br />

of human T and<br />

NK cells<br />

H. Schmidt, C. Gelhaus,<br />

M. Lettau,<br />

M. Nebendahl,<br />

M. Leippe, O. Janssen<br />

54. Propagation-deficient<br />

LCMV-derived vaccine<br />

vector efficiently<br />

targets dendritic cells to<br />

induce potent T and B<br />

cell responses against<br />

immunogens of choice<br />

L. Flatz, A. N. Hegazy,<br />

A. Verschoor,<br />

A. Bergthaler,<br />

M. Löhning,<br />

D. D. Pinschewer<br />

55. Vaccination with<br />

MHC class II-heterologous<br />

dendritic cells induces<br />

protective<br />

immunity against Leishmania<br />

major<br />

K. A. Remer, H. Moll<br />

62. The DEAD-box helicase<br />

DDX3X is a critical<br />

component of the TANKbinding<br />

kinase 1-dependent<br />

innate immune<br />

response<br />

D. Soulat,<br />

T. Buerckstuemmer,<br />

S. Westermayer,<br />

A. Goncalves, A. Bauch,<br />

A. Stefanovic,<br />

O. Hantschel,<br />

K. L. Bennett, T. Decker,<br />

G. Superti-Furga<br />

63. Post-transcriptional<br />

regulation of FasL expression:<br />

Molecular insights<br />

into storage,<br />

activation-induced mobilization<br />

and shedding<br />

of a prototypic death<br />

factor<br />

M. Lettau, O. Janssen<br />

Coffee Break / Poster Viewing / Exhibition<br />

70. Characterization of a<br />

novel, RORgt-expressing<br />

mucosal NK cell population<br />

S. L. Sanos, A. Mortha,<br />

V. Bui, K. Oberle,<br />

A. Diefenbach<br />

71. Specificity of interaction<br />

between killer cell<br />

immunoglobulin-like receptors<br />

(KIR) and MHC<br />

class I molecules of the<br />

rhesus macaque<br />

(Macaca mulatta)<br />

P. Kruse, C. Rosner,<br />

M. Hermes, L. Walter<br />

13<br />

78. Analysis of CD28 in<br />

horses and application<br />

of a polyclonal Ab to induce<br />

co-stimulation<br />

S. Ibrahim,<br />

E. Abd El-Gawad,<br />

F. Steinbach<br />

79. Species-specific<br />

generation of immune<br />

regulatory molecules by<br />

host pathogen coevolution<br />

R. Kammerer, T. Popp,<br />

S. Haertle, B. B. Singer,<br />

E. Travanty, Z. Qian,<br />

K. V. Holmes,<br />

W. Zimmermann


Scientific <strong>Programm</strong>e – Thursday, September 4, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />

16.45<br />

-<br />

18.00<br />

Parallel Symposium 2:<br />

Vaccination<br />

Chair: M. Müller, H.J. Schild<br />

Delineation of plasmablast characteristics<br />

generated in steady-state and in systemic<br />

immune responses<br />

H. Mei<br />

Towards a coronavirus- based multigene<br />

vaccine platform<br />

B. Ludewig<br />

Modulating Vaccine Responses with<br />

Innate Immunity<br />

B. Pulendran<br />

19.00 Welcome Reception at the Vienna City Hall<br />

Parallel Symposium 2:<br />

In Vivo Imaging<br />

Chair: C. Scheinecker, C. Berek<br />

The In Situ Dynamics of Innate and Adaptive<br />

Immune Cell Behaviour Revealed By<br />

Intravital Multiphotometry Microscopy<br />

R. Germain<br />

In vivo imaging of Germinal Center B Cells<br />

A.E. Hauser<br />

Non-invasive imaging of inflammation -<br />

the quest for specificity<br />

A. W<strong>und</strong>er<br />

NUDIST COLONIES.<br />

CD-1-nude • NMRI-nude • BALB/c-nude<br />

We’ve improved the availability of our nude mouse strains.<br />

For more information, please contact us at:<br />

Call: +49 (0) 9761/ 406-0 • +31 (0) 43 40 77 310<br />

E-mail: dbestell@crl.com • nlbestel@crl.com<br />

scand@criver.de<br />

Parallel Symposium 2:<br />

Immunomodulation<br />

Chair: W. Ellmeier, E. Schmitt<br />

Probing Dendritic cell In vivo Functions<br />

S. Jung<br />

Tec kinases in T cell activation and<br />

function<br />

L. Berg<br />

14<br />

Inducible Foxp3-dependent or -independent<br />

human CD4+ regulatory T Cells.<br />

R. Bacchetta


Scientific <strong>Programm</strong>e – Friday, September 5, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />

08.15<br />

-<br />

09.30<br />

09.30<br />

-<br />

10.30<br />

Parallel Symposium 1:<br />

Innate Immunity: Regulation<br />

Chair: M. Säemann, W. Solbach<br />

Innate resistance, inflammation, and<br />

cancer<br />

G. Trinchieri<br />

Interferon regulatory factors and innate<br />

immunity in early life<br />

M. Goldman<br />

The mammalian target of rapamycin and<br />

innate immunity<br />

T. Weichhart<br />

Parallel Symposium 1:<br />

Mucosal Inflammation<br />

Chair: B. Bohle, D. Männel<br />

Role of epithelial barrier function in allergy<br />

P. Brandtzaeg<br />

A prominent role for mucosal cystine/cysteine<br />

metabolism in intestinal immunoregulation<br />

S. Meuer<br />

Tumor Necrosis Factor and the consequences<br />

of its ablation in vivo<br />

S. Nedospasov<br />

Coffee Break / Poster Viewing / Exhibition<br />

Parallel Symposium 1:<br />

Transplantation<br />

Chair: T. Wekerle, R. Schmidt<br />

Antibody-mediated transplant rejection<br />

G. Böhmig<br />

15<br />

Immune monitoring and therapy in transplantation<br />

- from bench-to -bedside<br />

H.D. Volk<br />

Tolerance through mixed chimerism: how<br />

close to clinical application is it?<br />

T. Wekerle


Scientific <strong>Programm</strong>e – Friday, September 5, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

10.30<br />

-<br />

12.15<br />

Allergy I<br />

Chair: H. Renz,<br />

F. Horak<br />

80. Tracing antigen signatures<br />

in the human<br />

IgE repertoire<br />

K. Marth,<br />

M. Novatchkova,<br />

M. Focke-Tejkl,<br />

S. Jenisch, S. Jäger,<br />

D. Kabelitz, R. Valenta<br />

81. Stable dust challenge<br />

inhibits allergic airway<br />

reactivity through<br />

TLRs 2, 3, 4, 7, 9 and/or<br />

other PRRs/TLRs<br />

R. Ferstl, S. Spiller,<br />

S. Dreher, H. Garn,<br />

H. Fehrenbach,<br />

E. Von Mutius, H. Renz,<br />

H. Wagner,<br />

C. J. Kirschning<br />

82. Composition of B<br />

cell receptor classic antigen-binding<br />

site regulates<br />

allergic airway<br />

inflammation in a murine<br />

model of experimental<br />

asthma<br />

S. Kerzel, J. Wagner,<br />

T. Rogosch, A. Yildirim,<br />

H. Fehrenbach, H. Garn,<br />

R. F. Maier,<br />

H. W. Schroeder Jr.,<br />

M. Zemlin<br />

83. High expression of<br />

inflammatory cytokines,<br />

chemokines and their receptors<br />

in lungs of mice<br />

during allergic asthma<br />

remission <strong>und</strong>erlies the<br />

persistence of chronic<br />

lung inflammation<br />

R. Bankoti,<br />

L. El-Housseiny,<br />

G. Dekan, O. Hoffmann,<br />

G. Stingl, M. M. Epstein<br />

84. Antigen -specific immunotherapy<br />

inhibited<br />

Th2 via GATA-3 and<br />

Th17 cells in an allergic<br />

asthma model.<br />

N. Zhivkova, R. Karwot,<br />

J. H. Maxeiner,<br />

P. Scholtes, K. Soo,<br />

S. Finotto<br />

85. Selective depletion<br />

of Foxp3+ cells in<br />

DEREG mice allows<br />

functional analysis of<br />

regulatory T cells during<br />

experimental allergic airway<br />

inflammation<br />

A. Hartl, K. Lahl,<br />

H. Hamad, A. Ö. Yildirim,<br />

H. Fehrenbach, R. Teich,<br />

H. Garn, H. Renz,<br />

B. Lambrecht,<br />

T. Sparwasser<br />

Regulatory Lymphocytes<br />

I<br />

Chair: L. Klein,<br />

T. Wekerle<br />

88. Analyses of a novel<br />

regulatory T cell subset<br />

in patients with Systemic<br />

Lupus Erythematosus<br />

(SLE)<br />

M. Bonelli,<br />

A. Savitskaya, E. Feierl,<br />

S. S. Smolen,<br />

C. Scheinecker<br />

89. CD4 + CD25 high regulatory<br />

T cells suppress T<br />

helper 1 but not T helper<br />

2 cytokines<br />

T. Bollinger,<br />

A. Bollinger, W. Solbach<br />

90. Induction of CD25 -<br />

Foxp3 - regulatory T cells<br />

by chronic antigen stimulation<br />

in vivo<br />

W. Hansen,<br />

A. M. Westendorf,<br />

J. Buer<br />

91. Transfer of in vitro<br />

expanded human<br />

CD45RA+CD4+CD25hig<br />

h regulatory T cells inhibits<br />

early expansion of<br />

conventional T cells in<br />

immunodeficient Rag2-/c-/-<br />

mice<br />

T. J. Boeld, J. Albrecht,<br />

K. Doser, R. Eder, J. Stahl,<br />

E. Typlt, E. Obermann,<br />

R. Andreesen,<br />

P. Hoffmann, M. Edinger<br />

92. Long-term vaccination<br />

efficiency is independent<br />

of regulatory T<br />

cells<br />

G. Gasteiger,<br />

W. Kastenmuller,<br />

L. Stross, D. H. Busch,<br />

T. Sparwasser, I. Drexler<br />

93. Retrovirally transduced,<br />

antigen-specific<br />

T cells for therapy of<br />

type 1 diabetes<br />

N. Mpofu, N. Saal,<br />

M. Hardtke-Wolenski,<br />

M. P. Manns, E. Jaeckel<br />

Alloimmunity & Tolerance<br />

Chair: B. Arnold,<br />

H. Ankersmit<br />

96. Role of IL-2 in induction<br />

of CD8 T cell tolerance<br />

by LSEC<br />

A. K. Schurich, M. Berg,<br />

A. Limmer, H. J. Schild,<br />

L. Diehl, P. A. Knolle<br />

97. Proliferation of CD8positive<br />

T cells in the Lumina<br />

of Rat Renal<br />

Allograft Blood Vessels<br />

V. Grau, G. Fuchs-Moll,<br />

W. Padberg<br />

98. Dickkopf 3, a novel<br />

modulator of T cell responses<br />

M. Papatriantafyllou,<br />

G. Moldenhauer,<br />

H. J. Gröne, C. Niehrs,<br />

G. J. Hämmerling,<br />

T. Oelert, B. Arnold<br />

99. Toag-1 enables prediction<br />

of CMV mediated<br />

transplant tolerance abrogation<br />

W. Gong, M. Klöpfel,<br />

K. Vogt, S. Haase,<br />

A. Reutzel-Selke,<br />

H. Volk, A. Pascher,<br />

B. Sawitzki<br />

100. Mutated CYLD affects<br />

the functional state<br />

of dendritic cells<br />

M. Bros, N. Wiechmann,<br />

V. Besche,<br />

N. Hövelmeyer,<br />

S. Reissig,<br />

S. Grabbe, A. Waisman,<br />

A. B. Reske-Kunz<br />

101. Enhanced nuclear<br />

export of NFATc1 and<br />

impaired translocation of<br />

NFATc2 is observed in<br />

anergic iTreg generated<br />

by tolerogenic DC<br />

H. S. Adler, R. Orth,<br />

K. Streck, E. Graulich,<br />

K. Steinbrink<br />

Pattern Recognition<br />

Receptors & Myeloid<br />

Cells<br />

Chair: S. Bauer,<br />

C. Bogdan<br />

104. Influence of viral infection<br />

on recognition of<br />

self RNA<br />

T. von Thülen, M. Nain,<br />

S. Bauer<br />

105. TLR7-dependent<br />

recognition of transfer<br />

RNA<br />

Y. Zhao, A. Kaufmann,<br />

K. Steinbach, S. Bauer<br />

106. Intrabody mediated<br />

retention of TLR2 and<br />

TLR9 in the ER to inhibit<br />

chronic inflammation<br />

T. Böldicke, S. Dreher,<br />

S. Somplatzki,<br />

L. Grosse-Hovest,<br />

B. Maaß,<br />

W. Lindenmaier,<br />

H. Wagner,<br />

C. Kirschning<br />

107. Analysis of Toll-like<br />

receptor 7 and Toll-like<br />

receptor 9 chimeric molecules<br />

J. Willemsen, P. Yu,<br />

S. Bauer<br />

108. The divergent role<br />

of the mammalian target<br />

of rapamycin (mTOR) in<br />

dendritic cells subtypes<br />

M. Haidinger,<br />

T. Weichhart,<br />

M. Poglitsch, M. Hecking,<br />

M. Zeyda, R. Geyeregger,<br />

J. Werzowa, W. H. Hörl,<br />

M. D. Säemann<br />

109. Mammalian target<br />

of rapamycin (mTOR) orchestrates<br />

the defense<br />

program of innate immune<br />

cells<br />

F. Schmitz, A. Heit,<br />

S. Dreher, K. Tittel,<br />

J. Mages, T. Haas,<br />

A. Krug, K. Janssen,<br />

C. V. Kirschning,<br />

H. Wagner<br />

Innate Immunity:<br />

Regulation<br />

Chair: M. Zeyda,<br />

K. Pfeffer<br />

16<br />

112. Suppression of<br />

adaptive immune responses<br />

by Toll-like receptor<br />

ligands<br />

B. Schumak, M. Brock,<br />

F. Jüngerkes,<br />

G. Hartmann, T. Tüting,<br />

P. Knolle, R. Zawatzky,<br />

S. Bauer, A. Limmer<br />

113. The cytoplasmic tail<br />

of CD45 is released from<br />

activated phagocytes<br />

and can act as an inhibitory<br />

messenger for<br />

T cells<br />

S. Kirchberger,<br />

O. Majdic, S. Blüml,<br />

C. Schrauf, J. Leitner,<br />

C. Gerner, W. Paster,<br />

N. G<strong>und</strong>acker, M. Sibilia,<br />

J. Stöckl<br />

114. Molecular mechanisms<br />

of Staphylococcus<br />

aureus-induced autophagy<br />

K. Sabel, D. Grumme,<br />

S. A. Leggio,<br />

A. Schnaith, M. Krönke,<br />

O. Krut<br />

115. 12/15-lipoxygenase<br />

is involved in the limitation<br />

of inflammation and<br />

tissue damage in murine<br />

arthritis<br />

G. Krönke,<br />

J. Katzenbeisser,<br />

S. Uderhardt, W. Baum,<br />

R. Axmann, J. Zwerina,<br />

G. Schett<br />

116. Promoter methylation<br />

status is changed<br />

with altered DEFB1 gene<br />

expression in COPD<br />

E. Andresen,<br />

J. Bullwinkel, C. Lange,<br />

H. Heine<br />

117. Macrophage phosphoproteome<br />

dynamics<br />

after LPS-stimulation<br />

and its shaping by the<br />

MAPK-Phosphatase<br />

DUSP1: a SILAC-based<br />

approach<br />

G. Weintz, J. Olsen,<br />

J. Mages, M. Mann,<br />

R. Lang


Scientific <strong>Programm</strong>e – Friday, September 5, 2008 (continued)<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

86. Molecular and functional<br />

analysis of the<br />

antigen receptor of Bet v<br />

1-specific helper T lymphocytes<br />

A. Neunkirchner,<br />

V. M. Leb,<br />

K. G. Schmetterer,<br />

H. J. Kueng, D. Haiderer,<br />

S. Mutschlechner,<br />

B. Bohle, W. F. Pickl<br />

87. Cloning, expression<br />

and mapping of allergenic<br />

determinants of<br />

alphaS1-casein, a major<br />

cow’s milk allergen<br />

U. Schulmeister,<br />

H. Hochwallner,<br />

I. Swoboda, M. Focke-<br />

Tejkl, M. Nystrand,<br />

A. Harlin, J. Thalhamer,<br />

S. Scheiblhofer, W. Keller,<br />

B. Niggemann, S. Quirce,<br />

C. Ebner, A. Mari,<br />

G. Pauli, B. Geller,<br />

U. Herz, R. Valenta,<br />

S. Spitzauer<br />

Time Lecture Hall 2<br />

12.15<br />

-<br />

13.45<br />

94. BAC-transgenic mice<br />

for depletion of Foxp3 +<br />

regulatory T cells:<br />

Homeostatic expansion<br />

of Tregs<br />

J. Suffner,<br />

K. Hochweller, N. Garbi,<br />

G. Hämmerling<br />

95. Lack of Foxp3 Treglinage<br />

marker expression<br />

in mouse epithelial cells<br />

C. T. Mayer, K. Lahl,<br />

C. Loddenkemper,<br />

T. D. Sparwasser<br />

102. Allogeneic disparities<br />

in the surface molecule<br />

immunoglobulin-like<br />

transcript 5 (ILT-5) induce<br />

potent antibody responses<br />

in stem cell<br />

transplanted patients<br />

K. Pfistershammer , ,<br />

A. Lawitschka, J. Leitner,<br />

C. Klauser, R. Weigl,<br />

G. Böhmig, G. F. Fischer,<br />

M. Heemskerk,<br />

O. Majdic, W. F. Pickl,<br />

H. Greinix, P. Steinberger<br />

103. Dendritic cell-activated,<br />

endothelial cellspecific<br />

CTL recognizing<br />

a minor histocompatibility<br />

antigen rapidly induce<br />

transplant vasculopathy<br />

B. B. Bolinger,<br />

D. Engeler, P. Krebs,<br />

S. Miller, B. Ludewig,<br />

M. Hoffmann, P. Clavien,<br />

Y. Tian<br />

110. Hsp60 modulates<br />

neutrophil functions<br />

A. Osterloh,<br />

M. Piedavent,<br />

F. Geisinger,<br />

B. Fleischer, N. Brattig,<br />

M. Breloer<br />

111. Spatial separation<br />

of cross-presentation<br />

and endogenous antigen<br />

presentation<br />

S. Burgdorf, C. Schölz,<br />

A. Kautz, R. Tampé,<br />

C. Kurts<br />

Satellite Lunch Symposium - Octapharma<br />

Immune modulation with intravenous immunoglobulin: the established and the advances<br />

Chair: S. Meuer<br />

17<br />

118. Prophylactic blockade<br />

of TLR4 or therapeutic<br />

blockade of both<br />

TLR2 and TLR4 protects<br />

mice from Gram-negative<br />

infection and subsequent<br />

antibiotic therapy<br />

induced fatal septic<br />

shock<br />

C. J. Kirschning,<br />

G. Elson, R. Ferstl,<br />

S. Dreher, T. Müller,<br />

M. Freudenberg,<br />

B. Daubeuf, H. Wagner,<br />

S. Spiller<br />

119. Biological characterization<br />

of mouse beta<br />

defensin 14 - an orthologue<br />

of human beta<br />

defensin 3<br />

J. Röhrl, T. Hehlgans<br />

Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and autoimmune diseases<br />

P. Imbach<br />

Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacy<br />

F. Nimmerjahn<br />

Basic research in human immunology creates new therapeutic options<br />

S. Meuer<br />

Discussion and wrap-up<br />

Time Lecture Hall 1<br />

13.00<br />

-<br />

13.45<br />

Drittmittelförderung der DFG: Kriterien <strong>für</strong> eine erfolgreiche Antragstellung<br />

Chair: Y. Samstag<br />

A. Strecker


Scientific <strong>Programm</strong>e – Friday, September 5, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

14.00<br />

-<br />

15.30<br />

Infection I<br />

Chair: F. Schmitz,<br />

S. Ehlers<br />

120. Restricted B cell receptor<br />

diversity converts<br />

acute into chronic viral<br />

infection<br />

A. Bergthaler, L. Flatz,<br />

A. Verschoor,<br />

A. N. Hegazy,<br />

E. Horvath, M. Holdener,<br />

K. Fink, B. Odermatt,<br />

D. D. Pinschewer<br />

121. Interleukin 18 is essential<br />

for protective immunity<br />

against M.<br />

tuberculosis.<br />

B. Schneider,<br />

D. Korbel, K. Hagens,<br />

M. Koch,<br />

S. H. Kaufmann,<br />

H. Mittruecker,<br />

U. E. Schaible<br />

122. Wnt/Frizzled signaling<br />

in infectious diseases:<br />

Deciphering the<br />

role of FZD1 in mycobacterial<br />

infections<br />

N. Reiling,<br />

T. Endermann, S. Ehlers,<br />

J. Neumann<br />

123. Cavity formation in<br />

tuberculosis is mediated<br />

by interleukin-4 receptor-alpha-dependent<br />

mechanisms<br />

L. Heitmann,<br />

T. Schreiber, T. Thye,<br />

A. N. McKenzie,<br />

A. Cutler, F. Brombacher,<br />

R. D. Horstmann,<br />

C. G. Meyer, S. Ehlers,<br />

C. Hoelscher<br />

124. Immunological inhibition<br />

of gC1qR/p33, a<br />

receptor for C1q, decreases<br />

adherence of<br />

Staphylococcus aureus<br />

to microvascular endothelium<br />

S. Sethi, M. W. Laschke,<br />

J. Roller, L. von Mueller,<br />

E. Peerschke,<br />

B. Ghebrehiwet, I. Bajric,<br />

M. D. Menger,<br />

M. Herrmann<br />

125. The fibrin-derived<br />

peptide B 15-42 (FX06)<br />

for treatment of capillary<br />

leak<br />

M. Gröger, W. Pasteiner,<br />

G. Ignatyev, U. Matt,<br />

S. Knapp, P. Friedl,<br />

D. Zinkl, K. Zacharowski,<br />

R. Hofer-Warbinek,<br />

P. Petzelbauer,<br />

S. Reingruber<br />

Allergy II<br />

Chair: B. Linhart,<br />

G. Stary<br />

128. HLA-classII/peptide-TCR<br />

interactions of<br />

the single immunodominant<br />

T cell epitope of Art<br />

v 1, the major mugwort<br />

pollen allergen<br />

B. Jahn-Schmid,<br />

B. Maillere, V. Leb,<br />

W. Pickl, G. Gadermaier,<br />

F. Ferreira, B. Bohle<br />

129. Proteomic analysis<br />

and mass-spectrometric<br />

identification of differentially<br />

regulated proteins<br />

in primary human keratinocytes<br />

by allergens<br />

S. Ohnesorge, L. Dietz,<br />

P. Pankert,<br />

M. Schnoelzer,<br />

H. Thierse<br />

130. Immunosuppression<br />

and allergy in organ<br />

transplant recipients: evidence<br />

for insufficient<br />

control of allergen specific<br />

responses<br />

T. Eiwegger, S. Gruber,<br />

C. Geiger, E. Dehlink,<br />

T. Frischer, P. Jaksch,<br />

W. Klepetko,<br />

Z. Szépfalusi<br />

131. Long-term tolerance<br />

in IgE-mediated allergy<br />

through molecular<br />

hematopoietic<br />

chimerism in a murine<br />

model<br />

U. Baranyi, B. Linhart,<br />

N. Pilat, M. Gattringer,<br />

C. Klaus, E. Schwaiger,<br />

F. Muehlbacher,<br />

J. Iacomini, R. Valenta,<br />

T. Wekerle<br />

132. Generation of an<br />

IgE knock-in mouse and<br />

its use in systemic anaphylaxis<br />

in vivo<br />

P. Yu, W. Lübben,<br />

S. Bauer<br />

133. Murine plasma and<br />

non-plasma B cells express<br />

different IgE repertoires<br />

T. Rogosch, S. Kerzel,<br />

L. Sikula, R. Maier,<br />

M. Zemlin<br />

Regulatory Lymphocytes<br />

II<br />

Chair: A. Rosenkranz,<br />

H. Schulze-Koops<br />

136. Generation of induced<br />

CD8+Foxp3+ regulatory<br />

T cells in vitro<br />

C. Mayer, K. Lahl,<br />

D. Dittlein, V. Wenzel,<br />

O. Gassner, J. Stephani,<br />

C. Loddenkemper,<br />

T. Sparwasser<br />

137. CD8 + CD38 + T-cells:<br />

A competent regulatory<br />

T-cell population<br />

A. Bollinger,<br />

H. Fehrenbach,<br />

T. Bollinger, T. Bollinger,<br />

Z. Orinska,<br />

S. Bulfone-Paus<br />

138. Tolerogenic potential<br />

of lentivirally transduced<br />

murine DC<br />

overexpressing antiinflammatory<br />

molecules<br />

V. Besche,<br />

N. Wiechmann,<br />

S. Trojandt, S. Grabbe,<br />

A. B. Reske-Kunz,<br />

M. Bros<br />

139. IL-27 inhibits the<br />

development of regulatory<br />

T cells via STAT3<br />

M. Huber, V. Steinwald,<br />

A. Guralnik, A. Brüstle,<br />

P. Kleemann,<br />

C. Rosenplänter,<br />

T. Decker, M. Lohoff<br />

140. Development of<br />

“would-be” regulatory T<br />

cells and defective control<br />

of Th2-cytokine production<br />

in natural scurfy<br />

mutant mice<br />

K. I. Lahl, C. T. Mayer,<br />

J. Huehn, C. Loddenkemper,<br />

G. Eberl,<br />

J. Buer, T. Sparwasser<br />

141. TLR2 ligands act<br />

directly on Treg to abrogate<br />

suppression of<br />

CD4+CD25- T cells<br />

H. Oberg, M. Juricke,<br />

S. Ussat, H. Ly,<br />

D. Kabelitz, D. Wesch<br />

Mucosal Immunity<br />

Chair: R. Förster,<br />

M. Pasparakis<br />

144. Role of the transcription<br />

factor PU.1 in<br />

human lamina propria<br />

macrophages<br />

F. A. Lasitschka,<br />

A. Heidtmann, T. Giese,<br />

G. Wabnitz,<br />

A. Schrödter, J. Winter,<br />

A. Ulrich, S. C. Meuer,<br />

J. Schröder-Braunstein<br />

145. Role of eosinophils<br />

in TGF-beta expression<br />

in human intestine<br />

F. Ulmer, S. C. Bischoff,<br />

A. Lorentz<br />

146. CD4 + Foxp3 + regulatory<br />

T cell expansion<br />

induced by antigen-driven<br />

interaction with intestinal<br />

epithelial cells<br />

independent of local<br />

dendritic cells<br />

A. M. Westendorf,<br />

D. Fleissner, S. Jung,<br />

A. D. Gruber, W. Hansen,<br />

J. Buer<br />

147. Split tolerance after<br />

oral vaccination of mice<br />

with recombinant Escherichia<br />

coli Nissle<br />

1917 expressing fimbrial<br />

adhesin K88<br />

K. A. Remer,<br />

M. Bartrow, H. Moll,<br />

T. A. Oelschläger<br />

148. The role of IL-23/IL-<br />

17 in Toxoplasma gondii<br />

induced small intestinal<br />

immunopatology<br />

M. L. Munoz-Roldan,<br />

D. Struck, M. Heimesaat,<br />

C. Hoelscher, U. Mueller,<br />

Y. Iwakura, N. Ghilardi,<br />

O. Liesenfeld<br />

149. The mesenteric<br />

lymph node regulates<br />

the amplitude of IgA<br />

secretion in the drained<br />

area: potential role of the<br />

spleen in the immune<br />

response against orally<br />

applied cholera toxin<br />

A. Hahn, N. Thiessen,<br />

R. Pabst, M. Ahrendt,<br />

U. Bode<br />

B-Lymphocytes<br />

Chair: V. Sexl,<br />

T. Winkler<br />

18<br />

152. Swiprosin 1 - positive<br />

regulator of BCR induced<br />

calcium flux<br />

C. Kroczek, C. Lang,<br />

A. Avramidou,<br />

L. Nitschke, A. Elter,<br />

H. M. Jäck, D. Mielenz<br />

153. Engagement of<br />

CD83 on B cells augments<br />

IgG1 response in<br />

vivo<br />

B. Kretschmer,<br />

K. Lüthje,<br />

S. Schneider,<br />

B. Fleischer, M. Breloer<br />

154. The analysis of intravital<br />

two-photon imaging<br />

of germinal<br />

centres implies a novel<br />

lymphocyte migration<br />

and affinity maturation<br />

model<br />

M. Meyer-Hermann,<br />

M. Figge<br />

155. Proapoptotic BH3only<br />

proteins Bim and<br />

Puma are essential for<br />

apoptosis of germinal<br />

center-derived memory<br />

B cells and antibodyforming<br />

cells<br />

S. Fischer , , D. Tarlinton,<br />

A. Strasser<br />

156. Identification of a<br />

chemokine receptor profile<br />

characteristic for mediastinal<br />

large B-cell<br />

lymphoma<br />

U. E. Höpken,<br />

I. Anagnostopoulos,<br />

M. Broemer,<br />

C. Scheidereit,<br />

K. Joehrens, M. Hübler,<br />

H. Stein, M. Lipp,<br />

B. Dörken, A. Rehm<br />

157. The adapter protein<br />

SLy2 represents a newly<br />

identified regulator of cytoskeletalrearrangements<br />

M. L. von Holleben


Scientific <strong>Programm</strong>e – Friday, September 5, 2008 (continued)<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

15.30<br />

-<br />

16.30<br />

Time Lecture Hall 2<br />

18.00<br />

-<br />

19.30<br />

175. Immunopathological<br />

basis of lymphocytic<br />

choriomeningitis virusinduced<br />

chorioretinitis<br />

and keratitis<br />

M. Zinkernagel, P. Krebs,<br />

B. Bolinger, S. Miller,<br />

B. Ludewig<br />

127. CD8 T cell-mediated<br />

immune responses<br />

against cross-presenting<br />

liver sinusoidal endothelial<br />

cells leads to hepatitis<br />

D. Stabenow,<br />

K. Gärtner, M. Svorcova,<br />

M. Odenthal, H. Dienes,<br />

U. Protzer, P. A. Knolle<br />

General Assembly DGfI<br />

Chair: S. Meuer<br />

134. Induced ablation of<br />

mast cells in adult mice:<br />

Slow recovery of mast<br />

cell populations in the<br />

tissues.<br />

J. Scholten,<br />

A. Gerbaulet, B. Hiller,<br />

W. Muller, T. Krieg,<br />

T. Buch, A. Waisman,<br />

K. Hartmann, A. Roers<br />

135. Timothy grass<br />

pollen major allergen Phl<br />

p 1 - a protease?<br />

K. Röschmann,<br />

P. König, A. J. Ulmer,<br />

A. Petersen<br />

142. Influence of<br />

CD4+CD25+ regulatory<br />

T cells on the<br />

transendothelial migration<br />

of CD4+CD25- T<br />

cells<br />

T. Bedke, M. Kretz,<br />

K. Mahnke, A. H. Enk<br />

143. Expansion of immune-suppressive<br />

V 9V 2 T cells as a novel<br />

regulatory mechanism of<br />

IL-12 secreting dendritic<br />

cells<br />

M. W. Traxlmayr,<br />

A. M. Dohnal, D. Wesch,<br />

D. Kabelitz, T. Felzmann<br />

Coffee Break / Poster Viewing / Exhibition<br />

150. The role of CXCR5<br />

in antigen-independent<br />

development and antigen-dependentmaturation<br />

of nose-associated<br />

lymphoid tissue (NALT)<br />

J. Krege, S. Seth,<br />

S. Hardtke, A. Marques<br />

Davalos-Misslitz,<br />

R. Förster<br />

151. T cell-specific deletion<br />

of gp130 renders<br />

the highly susceptible Interleukin-10<br />

deficient<br />

mouse mutant resistant<br />

to intestinal nematode<br />

infection<br />

N. Fasnacht,<br />

M. C. Greweling,<br />

M. Bollati-Fogolin , ,<br />

A. Schippers , , W. Müller ,<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />

16.45<br />

-<br />

18.00<br />

Parallel Symposium 2:<br />

Infection<br />

Chair: S. Knapp, I. Förster<br />

Origin of CD8+ effector and memory T cell<br />

subsets<br />

D.H. Busch<br />

Mutual host pathogen reactions in tuberculosis<br />

U. Schaible<br />

Innate immune response to pneumococcal<br />

pneumonia<br />

S. Knapp<br />

Parallel Symposium 2:<br />

Adaptive Immunity: Regulation<br />

Chair: H. Stockinger, L. Klein<br />

Innate and adaptive IL-17 in the control of<br />

immune responses<br />

B. Stockinger<br />

Autoregulatory circuits in inflammatory<br />

T cell responses<br />

A. Scheffold<br />

Innate Immunity in regulation of antibody<br />

mediated inflammation<br />

R.E. Schmidt<br />

19.30 Departure with buses to the Viennese “Heuriger” Fuhrgassl-Huber<br />

19<br />

158. Antigen receptor tail<br />

clue of class-switched<br />

memory B cells<br />

N. Engels, C. Heemann,<br />

L. König, T. Tsubata,<br />

S. Griep, V. Schrader,<br />

J. Wienands<br />

159. Role of basophils in<br />

immunological memory<br />

responses<br />

A. J. Denzel, U. Maus,<br />

M. Rodriguez Gomez,<br />

M. Niedermeier, Y. Talke,<br />

N. Göbel, M. Mack<br />

Parallel Symposium 2:<br />

Adaptive Immunity: B-Cells<br />

Chair: G. Zlabinger, H-M. Jäck<br />

Transcriptional control of B cell development<br />

M. Busslinger<br />

Memory B cell sub-populations<br />

J.C. Weill<br />

Plasma cell memory<br />

A. Radbruch


Scientific <strong>Programm</strong>e – Saturday, September 6, 2008<br />

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3<br />

08.45<br />

-<br />

10.00<br />

10.00<br />

-<br />

10.30<br />

Your Power for Health<br />

Parallel Symposium 1:<br />

Autoimmunity<br />

Chair: J. Smolen, H. Schulze-Koops<br />

The life history of an autoimmune driver<br />

clone<br />

E. Sercarz<br />

Immunopathogenesis of rheumatoid arthritis:<br />

induction of arthritogenic autoimmune<br />

reactions by proinflammatory stimuli<br />

G. Steiner<br />

Modeling multiple sclerosis: autoimmune<br />

T and B cells in the pathogenesis of the<br />

brain inflammatory disease<br />

H. Wekerle<br />

Moderne Antikörper-Analyse<br />

Immunologische Produkte<br />

von Greiner Bio-One<br />

Gleichbleibende <strong>und</strong> reproduzierbare<br />

Bindung von Proteinen<br />

Geeignet <strong>für</strong> Transmissions-, Fluoreszenz-<br />

<strong>und</strong> Lumineszenzmessungen<br />

Konstante, einheitliche Bindungseigenschaften<br />

Vielfältiges Spektrum an Microplatten<br />

<strong>und</strong> Streifen-Platten<br />

Kompatibel mit automatisierten Systemen<br />

Parallel Symposium 1:<br />

Inflammation<br />

Chair: J. Stöckl, K. Pfeffer<br />

Mechanisms of inflammatory bone<br />

destruction<br />

K. Redlich<br />

Novel cytokines in inflammatory diseases<br />

F. Liew<br />

IL-17 and kynurenines in pathogenic<br />

inflammation<br />

L. Romani<br />

Coffee Break / Exhibition<br />

Parallel Symposium 1:<br />

Allergy<br />

Chair: R. Valenta, J. Kalden<br />

Human Th17 cells<br />

S. Romagnani<br />

Greiner Bio-One GmbH | Bad Haller Straße 32 | A-4550 Kremsmünster | Phone: (+43) 75 83 67 91-0 | Fax: (+43) 75 83 63 18 | E-Mail: offi ce@at.gbo.com<br />

New facets in mast cell activation<br />

S. Bulfone-Paus<br />

From allergens to vaccines<br />

R. Valenta<br />

20<br />

www.gbo.com/preanalytics


Scientific <strong>Programm</strong>e – Saturday, September 6, 2008<br />

Time Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5<br />

10.30<br />

-<br />

12.15<br />

Autoimmunity II<br />

Chair: R. Schwinzer,<br />

G. Staffler<br />

160. CCR7 is essential for regulatory<br />

T cell function in anti-<br />

GBM glomerulonephritis<br />

K. Hochegger, A. Rosenkranz,<br />

A. Rot<br />

161. The nuclear receptor<br />

PPARgamma serves as an intrinsic<br />

regulator of Th17 cell differentiation<br />

L. Klotz , , I. Dani, S. Burgdorf,<br />

A. Waisman, G. Eberl,<br />

J. Alferink, B. Langhans,<br />

T. Klockgether, P. Knolle<br />

162. Spontaneous CD8+ T Cell<br />

Mediated Liver Inflammation in<br />

a Transgenic Mouse Model of<br />

Autoimmune Hepatitis<br />

M. Zierden, E. Kühnen,<br />

M. Odenthal, H. P. Dienes<br />

163. Peripheral T cells are the<br />

therapeutic targets of highdose<br />

glucocorticoids in experimental<br />

autoimmune<br />

encephalomyelitis<br />

S. Wüst, J. van den Brandt,<br />

J. P. Tuckermann, R. Gold,<br />

H. M. Reichardt, F. Lühder<br />

164. The proteasome inhibitor<br />

bortezomib depletes plasma<br />

cells and protects lupus mice<br />

from nephritis<br />

K. Neubert, S. Meister,<br />

K. Moser, F. Weisel, D. Maseda,<br />

K. Amann, T. H. Winkler,<br />

J. R. Kalden, R. E. Voll<br />

165. CD8 T cells specific for a<br />

glomerular antigen induce renal<br />

inflammation in a CD4 help dependent<br />

fashion and may<br />

cause progressing Glomerulonephritis<br />

F. Heymann, E. E. Hamilton-<br />

Williams, I. Ludwig-Portugall,<br />

S. Quaggin, J. Flöge, H. Gröne,<br />

C. Kurts<br />

166. A new model for inflammatory<br />

bowel disease: A transgenic<br />

mouse expressing a<br />

crossreactive T cell receptor<br />

recognizing murine and bacterial<br />

HSP60<br />

N. Schmidt, T. Joeris,<br />

U. Steinhoff<br />

167. NAADP/Ca 2+ signaling: a<br />

new therapeutic target for T cell<br />

mediated autoimmune disease<br />

F. Odoardi, C. Cordiglieri,<br />

W. Dammermann, B. Zhang,<br />

M. Hohenegger, B. V. Potter,<br />

A. Guse, A. Flügel<br />

Infection II<br />

Chair: V. Leksa,<br />

O. Sharif<br />

168. Immunemodulation by<br />

Siglec-E during Trypanosoma<br />

cruzi infection<br />

H. Erdmann, P. R. Crocker,<br />

B. Fleischer, T. Jacobs<br />

169. A novel Leishmania major<br />

amastigote culture system<br />

U. A. Wenzel, S. Möller,<br />

M. Klinger, S. Liebau, T. Laskay,<br />

G. van Zandbergen<br />

170. The elimination of<br />

Anaplasma phagocytophilum in<br />

vivo requires CD4+ T cells, but<br />

is independent of Th1 cytokines<br />

and a wide spectrum of<br />

effector mechanisms<br />

K. Birkner, Y. Kern, B. Steiner,<br />

C. Bogdan, F. D. von Loewenich<br />

171. Oxidized phospholipids inhibit<br />

phagocytosis via a PKA<br />

dependent mechanism<br />

U. Matt, O. Sharif, T. Furtner,<br />

K. Stich, A. Zivkovic, S. Knapp<br />

172. Control of Persistent HBV<br />

Infection by Hepatitis B Core<br />

Antigen-activated NK cells:<br />

A Possible Mechanism for the<br />

HBV Persistence<br />

L. Huang, P. Chen, P. Knolle<br />

173. Acute infection with a single<br />

hepatitis C virus strain in<br />

dialysis patients: analysis of<br />

adaptive immune response and<br />

its impact on viral sequence<br />

evolution<br />

L. Weseslindtner,<br />

C. Neumann-Haefelin, S. Viazov,<br />

A. Haberstroh, J. Kletzmayr,<br />

J. H. Aberle, J. Timm,<br />

S. R. Ross, R. Klauser-Braun,<br />

T. F. Baumert, M. Roggendorf,<br />

R. Thimme, H. Holzmann<br />

174. Type I Interferons as virulence-determining<br />

factors in<br />

Listeria monocytogenes infections<br />

B. Reutterer, S. Stockinger,<br />

A. Pilz, D. Soulat, R. Kastner,<br />

S. Westermayer, T. Rülicke,<br />

M. Müller, T. Decker<br />

126. Yersinia enterocolitica differently<br />

affects DC subpopulations<br />

in vivo<br />

S. E. Autenrieth, T. Linzer,<br />

P. Warnke, S. Schmitz,<br />

I. B. Autenrieth<br />

Complement System<br />

Chair: M. Kirschfink,<br />

M. Wahrmann<br />

176. Human factor H-related<br />

protein 4 (CFHR4) recruits Creactive<br />

protein to the surface<br />

of necrotic cells<br />

M. Mihlan, M. Hebecker,<br />

M. Huber-Lang, R. Dahse,<br />

P. F. Zipfel, M. Józsi<br />

177. Regulation of mouse ficolin-B<br />

expression in immune<br />

competent cells<br />

V. L. Runza, J. Kürchner,<br />

D. Weber-Steffens,<br />

D. N. Männel<br />

178. Functional analyses indicate<br />

pathogenic role of factor<br />

H autoantibodies in atypical<br />

hemolytic uremic syndrome<br />

S. Strobel, P. F. Hoyer,<br />

C. J. Mache, E. Sulyok,<br />

P. F. Zipfel, M. Józsi<br />

179. A dual role of the C5a receptor<br />

(C5aR) in acute and<br />

chronic dextran sulphate induced<br />

models of inflammatory<br />

bowel disease<br />

K. Johswich, M. Martin,<br />

A. Bleich, M. Kracht,<br />

O. Dittrich-Breiholz, E. Gessner,<br />

S. Suerbaum, C. Rheinheimer,<br />

A. Klos<br />

180. Candida albicans CaHGT1<br />

and its role in complement inhibition<br />

and modulation of other<br />

virulence factors<br />

I. Lesiak, G. Vogl,<br />

T. Schwarzmüller, M. P. Dierich,<br />

K. Kuchler, R. Würzner<br />

P419. Characterization of factor<br />

H binding to neutrophil granulocytes<br />

J. Losse, P.F. Zipfel, M. Józsi<br />

182. Rituximab-induced ADCC<br />

of tumour cells is variably<br />

modified by complement iC3b<br />

A. Dörr, C. Watzl,<br />

M. Kirschfink<br />

Cytokines, Chemokines &<br />

their receptors<br />

Chair: U. Höpken,<br />

M. Sibilia<br />

21<br />

183. gp130 on<br />

macrophages/neutrophils negatively<br />

regulates Th17 development<br />

during experimental<br />

tuberculosis<br />

J. Sodenkamp, I. Foerster,<br />

W. Mueller, C. Hoelscher<br />

184. The role of optineurin<br />

(FIP2) in adenovirus E3-14.7Kmediated<br />

inhibition of TNFR1<br />

apoptosis<br />

L. Klingseisen, G. Knoll,<br />

W. Schneider-Brachert<br />

185. Overlapping functions of<br />

IL-7 and TSLP in lymphoid development<br />

D. Finke, L. Flueck, A. G. Farr,<br />

A. G. Rolink, S. Chappaz<br />

186. Organ-specific suppression<br />

of CCL17 production<br />

through Interferon-<br />

T. Globisch, S. Stutte,<br />

V. Lukacs-Kornek, C. Kurts,<br />

I. Förster<br />

187. Down-regulation of IFNduring<br />

HPV-induced carcinogenesis<br />

B. Rincon-Orozco, F. Rösl<br />

188. An IFN reporter mouse<br />

model for the visualization of<br />

the initiation of the Type I interferon<br />

response in vivo<br />

P. Dresing, S. Scheu,<br />

R. M. Locksley<br />

189. Chemokine receptor CCR7<br />

contributes to a rapid and efficient<br />

clearance of lytic MHV-68<br />

from the lung while bronchusassociated<br />

lymphoid tissue harbors<br />

virus during latency<br />

J. R. Kocks, H. Adler,<br />

H. Danzer, K. Hoffmann,<br />

D. Jonigk, U. Lehmann,<br />

R. Förster<br />

190. IL-27 acts as a Priming<br />

Signal on Human Keratinocytes<br />

and Antigen- Presenting Cells<br />

J. Zeitvogel, T. Werfel,<br />

M. Wittmann


Immunity for Life<br />

Immunology for Health<br />

Venue<br />

International Congress Center Berlin (ICC Berlin)<br />

Neue Kantstraße / Ecke Messedamm<br />

14057 Berlin, Germany<br />

www.icc-berlin.de<br />

Under the auspices of EFIS<br />

2 nd European Congress<br />

of Immunology<br />

Congress President<br />

Prof. Dr. med. Reinhold E. Schmidt<br />

Medizinische Hochschule Hannover<br />

Klinik <strong>für</strong> Immunologie <strong>und</strong> Rheumatologie<br />

Carl-Neuberg-Straße 1<br />

30625 Hannover, Germany<br />

Phone: +49 (0)511– 532-6656<br />

Fax: +49 (0)511– 532-9067<br />

E-Mail: immunologie@mh-hannover.de<br />

September 13 – 16, 2009<br />

Berlin, Germany<br />

Congress Secretariat<br />

K.I.T. GmbH Association & Conference<br />

Management Group & Co. KG<br />

Kur<strong>für</strong>stendamm 71<br />

10709 Berlin, Germany<br />

Phone: +49 (0)30 – 246 03-0<br />

Fax: +49 (0)30 – 246 03-200<br />

E-Mail: eci2009@kit-group.org<br />

www.kit-group.org<br />

www.eci-berlin2009.com


Scientific <strong>Programm</strong>e – Saturday, September 6, 2008<br />

Time Lecture Hall 1<br />

10.30<br />

-<br />

12.45<br />

12.45<br />

-<br />

13.00<br />

Satellite Lunch Symposium - Phadia<br />

Vom rekombinanten Allergen zu neuen Allergietherapien<br />

Chair: R. Valenta, N. Reider<br />

Rekombinante Allergene: Vom Beginn zur Gegenwart<br />

H. Breiteneder<br />

Rekombinante Nahrungsmittelallergene<br />

K. Hoffmann-Sommergruber<br />

Klinische Anwendungen <strong>für</strong> rekombinante Allergene<br />

P. Schmid-Grendelmeier<br />

Klinische Erfahrungen mit Allergenchips<br />

J. M. Baron<br />

Die Komplexitaet von zellulären Allergietesten<br />

J. Kleine-Tebbe<br />

Immuntherapie <strong>und</strong> Verlaufkontrolle mit rekombinanten Allergenen<br />

G. Pauli<br />

Pause (mit Snack)<br />

Time Lecture Hall 1<br />

13.00<br />

-<br />

13.45<br />

14.00<br />

-<br />

14.30<br />

Klinische Fälle aus der <strong>Allergologie</strong>: Wie hätten Sie entschieden?<br />

Chair: Z. Szepfalusi, G. Pauli<br />

Werner Aberer, Reinhart Jarisch, Felix Wantke <strong>und</strong> Stefan Wöhrl präsentieren klinische Fälle aus der <strong>Allergologie</strong><br />

Best Poster Awards<br />

Chair: J. Smolen, S. Meuer<br />

Time Lecture Hall 2<br />

15.00 General Assembly ÖGAI<br />

Chair: J. Smolen, M. Säemann<br />

23


Warum soll ich in die Ferne schweifen,<br />

wenn mir ein Diagnostik unternehmen<br />

alles bietet, was ich brauche?<br />

Siemens Healthcare Diagnostics. Das Engagement, um Ihren<br />

individuellen Bedürfnissen auf den Gr<strong>und</strong> zu gehen.<br />

Oberste Priorität hat <strong>für</strong> Sie eine optimale Patientenbetreuung, <strong>und</strong> <strong>für</strong> uns, Ihnen dabei zu helfen, dieses<br />

Ziel zu erreichen. Dazu bietet Ihnen Siemens ein beachtliches Portfolio leistungsorientierter Systeme, ein<br />

umfangreiches Testmenü sowie innovative IT- <strong>und</strong> Servicelösungen an. Sprechen Sie mit unserem<br />

Expertenteam über Ihre Vorstellungen – gemeinsam finden wir die optimale Lösung <strong>für</strong> Sie. Treten Sie<br />

näher: www.siemens.com/customer-first<br />

Answers for life.<br />

A91DX-0701169-A1-0000 © 2008 Siemens Healthcare Diagnostics Inc. All rights reserved.


Poster Viewing 25<br />

Thursday, September 4, 2008<br />

09.30 – 10.30 hrs<br />

T-Lymphocytes I<br />

Chair: B. Jahn-Schmid, C. Scheinecker<br />

P001 – P028<br />

T-Lymphocytes II<br />

Chair: W. Pickl, H. Stockinger<br />

P029 – P056<br />

Innate Immunity: Antigen-Presenting Cells<br />

Chair: T. Weichhart, M. Gilliet<br />

P057 - P075<br />

Signal Transduction<br />

Chair: L.J. Berg, W. Ellmeier<br />

P076 - P094<br />

Tumor Immunology<br />

Chair: O.J. Finn, T. Blankenstein<br />

P095 - P117<br />

Thursday, September 4, 2008<br />

15.30 – 16.30 hrs<br />

Innate Immunity: Regulation<br />

Chair: M. Zeyda, S. Beissert<br />

P118 - P134<br />

Pattern Recognition Receptors & Myeloid Cells<br />

Chair: F. Schmitz, J. Stöckl<br />

P135 - P151<br />

NK Cells<br />

Chair: C. Watzl, V. Sexl<br />

P152 - P164<br />

Vaccines & Adjuvants<br />

Chair: H. Lassmann, T. Weichhart<br />

P165 - P187<br />

Immunomodulation<br />

Chair: M. Fischer, G. Zlabinger<br />

P188 - P208<br />

Friday, September 5, 2008<br />

09.30 – 10.30 hrs<br />

Alloimmunity & Tolerance<br />

Chair: G. Böhmig, M. Säemann<br />

P209 - P233<br />

Allergy<br />

Chair: B. Bohle, S. Bulfone-Paus<br />

P234 - P264<br />

Infection<br />

Chair: U. Schaible, S. Knapp<br />

P265 - P296<br />

Mucosal Immunity<br />

Chair: S. Meuer, P. Brandtzaeg<br />

P297 - P308<br />

Friday, September 5, 2008<br />

15.30 – 16.30 hrs<br />

Autoimmunity I<br />

Chair: R. Germain, E. Sercarz<br />

P309 - P329<br />

Autoimmunity II<br />

Chair: G. Steiner, J. Kalden<br />

P330 - P352<br />

Complement System and B-Lymphocytes<br />

Chair: F. Melchers, A. Radbruch<br />

P420 and P353 - P360<br />

Regulatory Lymphocytes<br />

Chair: L. Klein, R. Bacchetta<br />

P361 - P383<br />

Cytokines, Chemokines & their receptors<br />

Chair: F.Y. Liew, L. Romani<br />

P384 - P404<br />

Veterinary Immunology<br />

Chair: B. Kaspers, A. Saalmüller<br />

P405 - P418


Business Meetings<br />

As per date of printing<br />

Closed Business Meetings<br />

Wednesday, September 3, 2008<br />

10.00 – 12.00 hrs Steering Committee Meeting ECI 2009 Lecture Room 25 / Level 8<br />

12.00 – 14.30 hrs Vorstandssitzung DGfI Hotel Regina – Salon Makart<br />

Thursday, September 4, 2008<br />

11.00 – 13.00 hrs Promotion Committee Meeting des ECI 2009 Lecture Room 25 / Level 8<br />

12.30 – 14.00 hrs Sitzung der DGfI Kommission “Fachimmunologe” Lecture Room 13 / Level 7<br />

Friday, September 5, 2008<br />

12.00 – 14.00 hrs Arbeitskreise der DGfI Lecture Room 25 / Level 8<br />

Saturday, September 6, 2008<br />

09.00 – 11.00 hrs DGfI Educational Committee Lecture Room 25 / Level 8<br />

26


Satellite Lunch Symposia<br />

Thursday, September 4, 2008, 12.15 – 13.45 hrs, Lecture Hall 1<br />

B cell: Promising target in autoimmune diseases<br />

Chair: J. Smolen<br />

The biology of the B cell in autoimmune diseases<br />

A. Radbruch<br />

Clinical experiences with B cell therapies<br />

T. Dörner<br />

Safety: Experiences with Rituximab<br />

H-P. Brezinsek<br />

Friday, September 5, 2008, 12.15 – 13.45 hrs, Lecture Hall 2<br />

Immune modulation with intravenous immunoglobulin: the<br />

established and the advances<br />

Chair: S. Meuer<br />

Introduction<br />

S. Meuer<br />

Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and<br />

autoimmune diseases<br />

P. Imbach<br />

Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacy<br />

F. Nimmerjahn<br />

Basic research in human immunology creates new therapeutic options<br />

S. Meuer<br />

Discussion and wrap-up<br />

Saturday, September 6, 2008, 10.30 – 12.45 hrs, Lecture Hall 1<br />

Vom rekombinanten Allergen zu neuen Allergietherapien<br />

Chairs: R. Valenta, N. Reider<br />

Rekombinante Allergene: Vom Beginn zur Gegenwart<br />

H. Breiteneder<br />

Rekombinante Nahrungsmittelallergene<br />

K. Hoffmann-Sommergruber<br />

Klinische Anwendungen <strong>für</strong> rekombinante Allergene<br />

P. Schmid-Grendelmeier<br />

Klinische Erfahrungen mit Allergenchips<br />

J.M. Baron<br />

Die Komplexitaet von zellulaeren Allergietesten<br />

J. Kleine-Tebbe<br />

Immuntherapie <strong>und</strong> Verlaufkontrolle mit rekombinanten Allergenen<br />

G. Pauli<br />

12.45 - 13.00 Pause (mit Snack)<br />

13.00 - 13.45 Klinische Fälle aus der <strong>Allergologie</strong>: „Wie hätten Sie entschieden”<br />

27


Information on Posters<br />

Poster Topics<br />

P01 T-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P001 – P056<br />

P02 Innate Immunity: Antigen-Presenting Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P057 – P075<br />

P03 Signal Transduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P076 – P094<br />

P04 Tumor Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P095 – P117<br />

P05 Innate Immunity: Regulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P118 – P134<br />

P06 Pattern Recognition Receptors & Myeloid Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P135 – P151<br />

P07 NK cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P152 – P164<br />

P08 Vaccines & Adjuvants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P165 – P187<br />

P09 Immunomodulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P188 – P208<br />

P10 Alloimmunity & Tolerance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P209 – P233<br />

P11 Allergy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P234 – P264<br />

P12 Infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P265 – P296<br />

P13 Mucosal Immunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P297 – P308<br />

P14 Autoimmunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P309 – P352<br />

P15 B-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P353 – P360<br />

P16 Regulatory Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P361 – P383<br />

P17 Cytokines, Chemokines & their receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P384 – P404<br />

P18 Veterinary Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P405 – P418<br />

P19 Complement system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P420 – P420<br />

Posters will be on display from Wednesday, September 3, (15.00 hrs) to Saturday, September 6, 2008,<br />

(15.00 hrs).<br />

Poster mounting will be possible on: Wednesday, September 3, 2008 from 10:00 - 15:00.<br />

Removal will be possible on: Saturday, September 6, 2008 from 14:30 - 15:30.<br />

Please note that posters not removed by then, will be taken down by conference staff and will not be<br />

stored or forwarded to the authors after the meeting.<br />

You will find your poster board number in the author index at the end of the abstract book.<br />

Presence at Posters<br />

In order to enable discussion and interaction with other participants, we request you or another member of your<br />

group to be at your poster board at the following times:<br />

Thursday, September 4, 2008, 09.30 – 10.30 hrs<br />

T-Lymphocytes-1 P001 - P028<br />

T-Lymphocytes-2 P029 - P056<br />

Innate Immunity: Antigen-Presenting Cells P057 - P075<br />

Signal Transduction P076 - P094<br />

Tumor Immunology P095 - P117<br />

Thursday, September 4, 2008, 15.30 – 16.30 hrs<br />

Innate Immunity: Regulation P118 - P134<br />

Pattern Recognition Receptors & Myeloid Cells P135 - P151<br />

NK Cells P152 - P164<br />

Vaccines & Adjuvants P165 - P187<br />

Immunomodulation P188 - P208<br />

Friday, September 5, 2008, 09.30 – 10.30 hrs<br />

Alloimmunity & Tolerance P209 - P233<br />

Allergy P234 - P264<br />

Infection P265 - P296<br />

Mucosal Immunity P297 - P308<br />

Friday, September 5, 2008 15.30 – 16.30 hrs<br />

Autoimmunity-1 P309 - P329<br />

Autoimmunity-2 P330 - P352<br />

B-Lymphocytes P353 - P360<br />

Regulatory Lymphocytes P361 - P383<br />

Cytokines, Chemokines & their receptors P384 - P404<br />

Veterinary Immunology P405 - P418<br />

Complement System P420<br />

If this is not possible, please leave a note on your poster board detailing the times when you will be present at the board.<br />

28


Information for Speakers<br />

Projection and Technical Setting<br />

All rooms will be equipped with data- and overhead projection (no slides).<br />

It is essential that you load and view your presentation in the slide preview room preferably in the<br />

morning of the day your talk is scheduled, but no later than 2 hours in advance.<br />

The lecture rooms are exclusively equipped with Windows-PCs (no Macintosh machines). In case you<br />

absolutely need to use your own laptop or notebook, please contact the preview center well in advance<br />

of your talk.<br />

Please bring a USB-stick or CD-ROM, all formatted for Windows® (PC). You may want to carry a second<br />

disk/CD as a back-up in case there is any unsolvable technical problem.<br />

File Format: Microsoft® Power Point presentation formatted for Windows® (PC) only. (Operating<br />

system: Windows XP®)<br />

Preferred Resolution: XGA (1024 x 768 pixel)<br />

Preview Room<br />

The Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of your<br />

presentation is available in the preview room. All presenters should bring their electronic presentation to the preview<br />

room preferably in the morning of the day of the talk, but no later than 2 hours before the start of the session. For<br />

sessions starting at 08.15 hrs, the PowerPoint presentations should be handed in the previous day.<br />

Opening hours of the preview room:<br />

Wednesday, September 3, 2008 12.00 – 18.00<br />

Thursday, September 4, 2008 07.30 – 18.00<br />

Friday, September 5, 2008 07.30 – 18.00<br />

Saturday, September 6, 2008 08.15 – 15.00<br />

<strong>Programm</strong>e Changes<br />

The organisers cannot assume any liability for changes in the programme due to external or unforeseen<br />

circumstances.<br />

29


Congress Information<br />

Abstract Books<br />

You will find an Abstract Book in your conference bag.<br />

Accreditation<br />

The Joint Annual Meeting of Immunology has applied for credits at the European Accreditation Council for Continuing<br />

Medical Education, Institution of the UEMS.<br />

The number of credits (which will be announced after the meeting) will figure on the respective confirmation,<br />

which will also be sent after the meeting.<br />

The rules of the EACCME state that participants are kindly asked to fill in the feedback (evaluation) form included<br />

in the conference bag. It can be returned to the registration desk.<br />

Participants applying for EACCME Credits will have to have their badge scanned daily at the registration<br />

desk before entering the conference. The confirmation will be mailed after the conference at the end of<br />

September.<br />

Die österreichische Akademie der Ärzte hat an diese Veranstaltung 41 Diplomfortbildungspunkte<br />

vergeben.<br />

Admission to Lecture Halls<br />

Participants are requested to enter the lecture halls via Level 8 only.<br />

Badges<br />

Participants will receive their name badges from the conference registration desk. Since only registered participants will be permitted<br />

to attend scientific sessions, the exhibition and poster areas, you are kindly asked to wear your badge when entering the<br />

congress venue. Please note that admission to scientific sessions is strictly restricted to participants wearing their badges. Exhibitors<br />

and accompanying persons are not entitled to attend the scientific sessions. Lost badges can be replaced at the registration<br />

desk. However, a handling fee of € 20,- will be charged.<br />

The following badge-colours are used at the Congress:<br />

White � Participants<br />

Yellow � Accompanying Persons<br />

Green � Exhibitors<br />

Red � Staff<br />

Cancellations and Ref<strong>und</strong>s<br />

Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.<br />

The policy for ref<strong>und</strong>ing registration fees is as follows:<br />

Written cancellation received:<br />

- before July 31, 2008: 75% ref<strong>und</strong><br />

- after July 31, 2008: no ref<strong>und</strong><br />

The date of the postmark or fax ID is the basis for considering ref<strong>und</strong>s. Ref<strong>und</strong>s will be made after the congress.<br />

Cash Bar<br />

Snacks and drinks may be purchased at the cash bar on Level 8 during congress hours.<br />

Certificate of Attendance<br />

Confirmations of attendance will be issued at the registration desk.<br />

City Tour<br />

The city tour “Classical Vienna – A City Stroll” will take place on Thursday, September 4, 2008. It is free of charge for accompanying<br />

persons, however, registration in advance is mandatory.<br />

Coffee Breaks<br />

During the session breaks, refreshments will be served free of charge to participants wearing name badges.<br />

Exhibition Opening Hours<br />

Wednesday, September 3, 2008 15.00 – 17.00 hrs<br />

Thursday, September 4, 2008 08.15 – 17.00 hrs<br />

Friday, September 5, 2008 08.15 – 17.00 hrs<br />

Saturday, September 6, 2008 08.45 – 15.00 hrs<br />

Hotel and Tours Desk<br />

Mondial, the official travel agency of the meeting, will be present at the conference on<br />

Wednesday, September 3, 2008 from 14.30 – 17.30 hrs and on<br />

Thursday, September 4, 2008 from 07.30 – 09.30 hrs.<br />

If you have any questions regarding your hotel booking or the city tour, please approach Mondial. They will be located near the<br />

registration desk.<br />

Internet<br />

A few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internet<br />

cafés throughout the city.<br />

30


Congress Information<br />

Message Board<br />

A Message Board and notice of the daily programme are available on Level 7 and Level 8.<br />

Poster Mounting and Removal<br />

There are four poster sessions: Thursday and Friday from 09.30 – 10.30 hrs and from 15.30 – 16.30 hrs. Poster mounting will be<br />

possible on Wednesday, September 3, 2008 from 10.00 – 15.00 hrs. Poster removal will be possible on Saturday, September 6,<br />

2008 from 14.30 – 15.30 hrs. Please note that the organisers cannot assume any liability for loss or damage of posters displayed<br />

in the poster area. Posters that are not removed by 15.30 hrs on Saturday, September 6, 2008 will be removed by staff and will<br />

not be stored or forwarded to the author after the meeting.<br />

Preview Room<br />

The Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of your presentation<br />

is available in the preview room. All presenters should bring their electronic presentation to the preview room preferably in<br />

the morning of the day of the talk, but not later than 2 hours before the start of the session. For sessions starting at 08.15 hrs,<br />

the PowerPoint presentations should be handed in the previous day.<br />

Following are the opening hours of the preview room:<br />

Wednesday, September 3, 2008 12.00 – 18.00<br />

Thursday, September 4, 2008 07.30 – 18.00<br />

Friday, September 5, 2008 07.30 – 18.00<br />

Saturday, September 6, 2008 08.15 – 15.00<br />

Public Transport<br />

Registered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all public<br />

transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for going<br />

to the airport, since the airport is out of town. Congress participants are kindly requested to return their ticket if it is not needed.<br />

Registration Desk opening hours<br />

Wednesday, September 3, 2008 10.00 – 18.00<br />

Thursday, September 4, 2008 07.30 – 18.00<br />

Friday, September 5, 2008 07.30 – 18.00<br />

Saturday, September 6, 2008 08.15 – 15.00<br />

Smoking Policy<br />

The Joint Annual Meeting of Immunology is a “No-smoking-Conference”. Please note that smoking is banned from all public<br />

buildings. Restaurants and bars may, depending on size, be declared either as “smoking” or “no-smoking” locations or have<br />

separate areas and ventilation systems.<br />

Staff<br />

Should you have any questions, congress staff, recognizable by a blue t-shirt and red badge, will be pleased to help you.<br />

31


Registration Fees<br />

Onsite registration<br />

Wednesday, September 3, 2008 10.00 – 18.00<br />

Thursday, September 4, 2008 07.30 – 18.00<br />

Friday, September 5, 2008 07.30 – 18.00<br />

Saturday, September 6, 2008 08.15 – 15.00<br />

Payment received before June 15, 2008 after June 15, 2008 and on-site<br />

Members EUR 190.— EUR 300.—<br />

Student Members* EUR 95.— EUR 135.—<br />

Non-Members EUR 280.— EUR 390.—<br />

Student Non-Members* EUR 140.— EUR 180.—<br />

Accompanying Persons EUR 60.— EUR 60.—<br />

Day Ticktet Member EUR 140,—<br />

Day Ticket Non-Member EUR 180,—<br />

* please provide a copy of an ID together with your registration<br />

What is covered by the registration fee?<br />

Participants Accompanying persons<br />

Admission to all scientific sessions<br />

Access to the exhibition<br />

Coffee breaks<br />

Welcome reception at the City Hall<br />

Thursday, September 4, 2008, 19.00 hrs<br />

Abstract book<br />

<strong>Programm</strong>e<br />

4-days public transport ticket<br />

Payment of registration fees may be made in cash (Euros only), by maestro debit card, or by the following credit cards:<br />

Diners Club, Mastercard, Visa.<br />

Please note that the reduced registration fee is only applicable if it has been credited to the congress account before the deadline.<br />

Registering without performing an actual payment is not sufficient to benefit from the reduction. Pre-registration without<br />

payment of the registration fee is possible. The full fee is to be paid at the registration desk.<br />

Cancellations and ref<strong>und</strong>s:<br />

Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.<br />

Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.<br />

The policy for ref<strong>und</strong>ing registration fees is as follows:<br />

Written cancellation received:<br />

- before July 31, 2008: 75% ref<strong>und</strong><br />

- after July 31, 2008: no ref<strong>und</strong><br />

The date of the postmark or fax ID is the basis for considering ref<strong>und</strong>s. Ref<strong>und</strong>s will be made after the congress.<br />

32<br />

Admission to the welcome reception at the City Hall<br />

Thursday, September 4, 2008, 19.00 hrs<br />

Classical Vienna City Tour*,<br />

Thursday, September 4, 2008, 09.00 hrs<br />

Access to the exhibition and coffee breaks<br />

(no admission to lectures)<br />

*Please note that the classical city tour is not available for<br />

on site registrations of accompanying persons.


General Information<br />

Bank services - Money matters<br />

Banks are open from 8.30 – 12:30 and from 13:30 – 15:00, Monday to Friday. Some banks are also open on Thursday afternoons<br />

until 17:30 hrs. Cash machines (ATMs), which accept all major international bank cards, are available throughout the city. There<br />

is a cash machine in the main entrance of the Vienna General Hospital. The currency of Austria is the Euro (€). Major credit cards<br />

are widely accepted, but please always check beforehand.<br />

Car Parking<br />

The Vienna General Hospital has approximately 800 car parking spaces available for visitors in an <strong>und</strong>ergro<strong>und</strong> car park. The<br />

entrance is at Währinger Gürtel.<br />

Eating out in Vienna<br />

Vienna has a broad variety of local and international restaurants, many of them located in the old city and in the vicinity of the conference<br />

venue.<br />

Emergency services<br />

The phone number to dial for emergencies is 112.<br />

GSM cell phone roaming<br />

GSM cell/mobile phone roaming is available without any problems for all major international providers. It is advisable to inquire<br />

beforehand at your provider which roaming company in Austria offers the cheapest tariffs.<br />

Insurance<br />

In registering for the Joint Annual Meeting of Immunology 2008 participants agree that neither the organising committee nor<br />

the congress office assume any liability whatsoever. Participants are requested to make their own arrangements for health and<br />

travel insurance.<br />

Internet and printing facilities<br />

A few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internet<br />

cafés throughout the city.<br />

Language<br />

The official language of the congress will be English (no simultaneous translation).<br />

Medical care<br />

The Austrian National Health Service may be used by all persons from European Union countries who have the E111 Form (EHI-<br />

Card). This form/card should be obtained at the health service or post office of the visitor’s home country before travelling to<br />

Austria. It is advisable for participants from countries outside the European Union to take out medical insurance before reaching<br />

Austria, since they will be charged for access to the national health system.<br />

Pharmacies<br />

Medicines that do not require a medical prescription may be purchased over the counter. If you need advice, do not hesitate to<br />

ask the pharmacist. If you usually take medication, it is advisable to bring a sufficient amount with you for your trip. Pharmacies<br />

in the vicinity of the conference venue are on Zimmermannplatz 1, 1090 Vienna. There are duty pharmacies open 24 hours a day.<br />

Outside each pharmacy there is a list of the nearest duty pharmacies, or you may ask at your hotel reception for more information.<br />

Safety - Crime<br />

Visitor safety is generally adequate. Like in any other major European city, you can walk everywhere using common sense. Pick<br />

pocketing in heavily visited tourist zones or in public transport lines might be a concern.<br />

Unfortunately experience has shown that some basic precautionary measures should always be kept in mind in any city:<br />

- Do not carry important items like flight tickets, passports etc. with you when visiting the conference or strolling through the city;<br />

leave them in the hotel safe during your stay. Rather carry a photocopy of your passport or an identity card with you.<br />

- Try not to carry all documents, money, credit cards and other essential items and valuables in one bag. If it gets lost or stolen,<br />

everything will be gone and might be difficult to replace on short notice, especially passports and visa to return to your country<br />

of residence.<br />

- Take off your name badge when leaving the conference centre.<br />

Shops<br />

Shops in Vienna are generally open between 09.00 and 18.00 hrs Mon-Fri, and between 09.00 and 12.00 on Saturdays. Some<br />

shops are open until 19.00 Mon-Fri and until 17.00 on Saturdays. Shops are usually closed on S<strong>und</strong>ays, except for a few establishments<br />

with special permits.<br />

Taxis<br />

There are Taxi ranks throughout the city, but calling is often your best option. Please address your hotel reception or the registration<br />

desk of the conference venue. A taxi station can be fo<strong>und</strong> in front of the main entrance at Level 5 and at Lazarettgasse<br />

(exit on Level 4).<br />

Tipping<br />

Tips are not obligatory in Austria, although people usually tip approximately 10% at restaurants, cafés and bars. Hotel and airport<br />

porters will accept tips, depending on the luggage.<br />

33


General Information<br />

Travelling within Vienna<br />

Registered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all public<br />

transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for going<br />

to the airport, since it is out of town. Congress participants are kindly requested to return their ticket if it is not needed.<br />

For accompanying persons and exhibitors tickets are available from machines at <strong>und</strong>ergro<strong>und</strong> stations (maestro debit cards accepted),<br />

at news agents’, or at Vienna Transport Authority’s ticket offices. Tickets bought in advance are cheaper and must be<br />

punched in a blue ticket cancelling machine on the tram or bus, or at the barrier before boarding the <strong>und</strong>ergro<strong>und</strong> train.<br />

Single trip tickets can be used for any single trip within Vienna. You may change lines (and switch between bus, tram, <strong>und</strong>ergro<strong>und</strong>,<br />

or urban train), but you may not interrupt your journey. Ticket price: EUR 1.70 when bought in advance; EUR 2.20 when<br />

bought in the means of transport.<br />

The 24-hour pass is valid throughout Vienna for exactly 24 hours from the time it is punched. Price: EUR 5.70<br />

The 72-hour pass is valid throughout Vienna for exactly 72 hours from the time it is punched. Price: EUR 13.60<br />

The 8-day ticket is valid for any eight days, not necessarily eight consecutive days. It is a rover ticket, which means you can travel<br />

all aro<strong>und</strong> Vienna. You can also use the ticket for several people travelling together. Simply punch one strip for each person in the<br />

group. Price: EUR 27.20<br />

Week-pass valid from Monday to Monday, 09.00 hrs. Price: EUR 14.00<br />

A taxi is the most comfortable way of getting aro<strong>und</strong> the city but also the most expensive. They are identifiable by their roof-sign<br />

which is lit when available. Prices must be displayed inside the cab and meters (which are compulsory in all cabs) will indicate<br />

the fare.<br />

Travelling from and to the Airport<br />

Vienna International Airport is located 13 kilometres south east of Vienna.<br />

City Airport Train (CAT)<br />

The train service between the airport and the city centre (City Air Terminal – Station ‘Wien Mitte’) is every 30 minutes and takes<br />

16 minutes. It is covered from 6:05 hrs to 00:05 hrs (Airport to City) and from 5:38 hrs to 23:38 hrs (City to Airport). Tickets may<br />

be purchased online (EUR 8.00 single or EUR 15.00 return), from ticket machines at the airport/station (EUR 9.00 single or EUR<br />

16.00 return) or on board (EUR 10.00 single). From ‘Wien Mitte’ you can take the green line (U4) direction Heiligenstadt and get<br />

off at ‘Spittelau’ (five stops) and then take the brown line (U6) direction Siebenhirten and get off at Michelbeuern-Allgemeines<br />

Krankenhaus.<br />

Taxi fares to the conference venue are about EUR 35.00 and take aro<strong>und</strong> 25 minutes. There is a taxi rank outside the airport terminal.<br />

Night-time fees are slightly higher.<br />

Travelling to the Vienna General Hospital by Public Transportation<br />

The Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 (the brown line) and getting<br />

off at Michelbeuern – Allgemeines Krankenhaus. Furthermore, it can be reached by tramway 42, tramways 5 and 33 (stop<br />

Lazarettgasse) as well as tramways 43 and 44 (stop Alser Straße).<br />

Vienna<br />

Vienna, the capital of Austria, 2 million inhabitants, is situated on the banks of the Danube. Vienna is a dream city for anyone with<br />

an interest in history. Narrow, medieval alleyways and grand boulevards lead to historic sights such as the Imperial Palace (Hofburg),<br />

Belvedere Palace, Burgtheater, the Spanish Riding School, St. Stephen’s Cathedral, the Opera House, Karlskirche, or<br />

Schönbrunn Palace. Vienna has been synonymous with music for centuries, and was home to Mozart, Beethoven, Schubert and<br />

Johann Strauss. The Vienna Philharmonic Orchestra is one of the world’s top orchestras; the Vienna Boys’ Choir is triumphantly<br />

successful wherever it tours. Vienna possesses a lively and vast array of cultural attractions, from classical or experimental theatre,<br />

film or dance festivals, opera or operetta, to exhibitions and concerts. The Museum of Fine Arts is one of the world’s largest<br />

and most distinguished museums, housing priceless works of art. Art accompanies you wherever you go in Vienna - even some<br />

of its <strong>und</strong>ergro<strong>und</strong> stations are listed properties on account of their elegant, ornamental Jugendstil (Art Nouveau) style designed<br />

by Otto Wagner. For more information about Vienna, please see www.aboutvienna.org.<br />

34


Venue<br />

Location of the Vienna General Hospital and the Lecture Centre<br />

GENERAL INFORMATION<br />

Congress venue<br />

Vienna General Hospital<br />

Allgemeines Krankenhaus Wien<br />

Lecture Hall Centre<br />

Hörsaalzentrum<br />

Währinger Gürtel 18-20<br />

A-1090 Vienna, Austria<br />

HÖRSAALZENTRUM<br />

EBENE 07/08<br />

Public transportation in Vienna<br />

The Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 and getting off<br />

at the station ”Michelbeuern – Allgemeines Krankenhaus”. Furthermore it can be reached with the tramway 42, the<br />

tramway 5 and 33 (station ”Lazarettgasse”) as well as the tramways 43 and 44 (station ”Alser Strasse”)<br />

35


Venue 36<br />

Level 7<br />

Access from main entrance<br />

No entrance to Lecture Halls.<br />

Please use the doors on Level 8.<br />

Meeting<br />

Room 13<br />

Level 8<br />

Access to Lecture Halls<br />

? Entrance to Lecture Halls<br />

Escalators to main entrance<br />

Green Elevators to main entrance<br />

Lecture<br />

Hall 2<br />

?? ? ? ? ?<br />

Lecture<br />

Hall 1<br />

Lecture<br />

Hall 3<br />

? ? ? ? ? ?<br />

Coffee<br />

Escalators to main entrance<br />

Green Elevators to main entrance<br />

Lecture<br />

Hall 2<br />

Exhibition<br />

Registration<br />

Red Elevators<br />

Lecture<br />

Hall 5<br />

Lecture<br />

Hall 4<br />

Coffee<br />

e<br />

e<br />

f<br />

f<br />

o<br />

C<br />

n<br />

o<br />

i<br />

t<br />

i<br />

b<br />

i<br />

h<br />

x<br />

E<br />

?? ? ? ? ?<br />

Lecture<br />

Hall 1<br />

Lecture<br />

Hall 3<br />

? ? ? ? ? ?<br />

Posters and Exhibition<br />

Coffee<br />

Red Elevators<br />

Lecture<br />

Hall 5<br />

Lecture<br />

Hall 4<br />

Posters<br />

? ? ? ?<br />

s<br />

r<br />

e<br />

t<br />

s<br />

o<br />

P<br />

r<br />

a<br />

B<br />

h<br />

s<br />

a<br />

C<br />

n<br />

o<br />

i<br />

t<br />

i<br />

b<br />

i<br />

h<br />

x<br />

E<br />

Cloakroom<br />

Posters<br />

Preview<br />

Room<br />

Posters<br />

Meeting<br />

Room<br />

25<br />

Posters


Social Events<br />

Thursday, September 4, 2008, 19.00 hrs<br />

Welcome Reception by the Mayor of Vienna at the Vienna City Hall<br />

The mayor of the city of Vienna is pleased to invite you to a Welcome Reception. Meet your colleagues at this event. Enjoy the<br />

evening with a Buffet and live music.<br />

Dress code: business attire<br />

Attendance is free for registered participants and accompanying persons. Those who have registered prior to the congress<br />

should have received their ticket with the congress material. Please remember to bring your ticket.<br />

Please note that attendance is limited and advance registration is mandatory in order to receive a ticket!<br />

A limited number of tickets will still be available for onsite bookings.<br />

Venue: Vienna City Hall, Lichtenfelsgasse 2, 1010 Vienna<br />

Directions: From the conference venue take the brown <strong>und</strong>ergro<strong>und</strong> line U6 (direction Siebenhirten) one stop and get off at Alser<br />

Strasse. Take the tram 43 (direction Schottentor) and get off at Landesgerichtsstrasse. From there you can walk along Landesgerichtsstrasse<br />

until you reach the city hall on your left hand side. Walk past the city hall and turn left into Lichtenfelsgasse. The<br />

entrance to the reception is on your left.<br />

Alternatively you can take the brown <strong>und</strong>ergro<strong>und</strong> line U6 (direction ‘Floridsdorf’) three stops and get off at ‘Spittelau’. Take the<br />

green <strong>und</strong>ergro<strong>und</strong> line U4 (direction ‘Hütteldorf’) three stops and get off at ‘Schottenring’. Take the purple <strong>und</strong>ergro<strong>und</strong> line U2<br />

(direction ‘Karlsplatz’) two stops and get off at ‘Rathaus’. Take the exit towards the front of the train and turn left and cross the<br />

street. This is Lichtenfelsgasse. The entrance to the Reception is on the left hand side.<br />

Friday, September 5, 2008, 19.30 hrs.<br />

Dinner at a Viennese “Heuriger”<br />

An evening spent in typical Austrian wine taverns in Vienna. You will be served a delicious Austrian buffet and excellent local<br />

wines while enjoying the atmosphere of a traditionally decorated restaurant. “Heuriger” could be translated with “of this year”<br />

and means a young crisp wine produced during the current wine season. Only wine producers serving their own product,<br />

grown in the vineyards of Vienna, may call their tavern “Heuriger”.<br />

Dress code: casual<br />

Venue: Weingut Fuhrgassl Huber<br />

Neustift/Walde 68<br />

1190 Vienna<br />

Buses depart from the main entrance on Level 5 of the Vienna General Hospital, at 19.30 hrs and return in the late<br />

evening.<br />

Price per ticket including transport, music, food and beverages: EUR 45.–<br />

Please note that advance registration is mandatory in order to receive a ticket! A limited number of tickets will still be<br />

available for onsite bookings.<br />

37


Undergro<strong>und</strong> Map 38<br />

9<br />

Congress<br />

venue<br />

Welcome<br />

Reception


City Map 39<br />

��<br />

����������������������<br />

�����������������������<br />

�<br />

�<br />

1) Lecture Centre of the Vienna<br />

General Hospital (AKH)<br />

2) City Hall (Welcome Reception)<br />

3) Arcotel Boltzmann<br />

4) Mercure Josefshof<br />

5) Hotel & Palais Strudlhof<br />

6) Carlton Opera<br />

�<br />

�<br />

�<br />

�<br />

�<br />

��<br />

��<br />

�<br />

7) Wandl<br />

8) Atlas<br />

9) Academia<br />

10) Pension Ani Falstaff<br />

11) Pension Ani<br />

12) Regina<br />

13) Royal<br />

�<br />

��


Exhibition – General Information<br />

Exhibiton Organiser:<br />

Name MAW – Medizinische Ausstellungs- <strong>und</strong> Werbegesellschaft<br />

Address Freyung 6<br />

1010 Vienna, Austria<br />

Telephone Ms. Ingrid Winkler: +43 664 441 8285<br />

Ms. May-Britt Ernst: +43 664 105 2018<br />

Fax +43 1 535 6016<br />

E-mail maw@media.co.at<br />

Exhibition Dates & Opening hours:<br />

Wednesday, September 3, 2008 15.00 – 17.00 hrs<br />

Thursday, September 4, 2008 08.15 – 17.00 hrs<br />

Friday, September 5, 2008 08.15 – 17.00 hrs<br />

Saturday, September 6, 2008 08.45 – 15.00 hrs<br />

Poster Mounting, Poster Viewing, Poster Removal Hours<br />

Wednesday, September 3, 2008 – poster mounting 10.00 – 15.00 hrs<br />

Wednesday, September 3, 2008 – poster viewing 15.00 – 18.00 hrs<br />

Thursday, September 4, 2008 – poster viewing 08.15 – 18.00 hrs<br />

Friday, September 5, 2008 – poster viewing 08.15 – 18.00 hrs<br />

Saturday, September 6, 2008 – poster viewing 08.45 – 14.30 hrs<br />

Saturday, September 6, 2008 – poster removal 14.30 – 15.30 hrs<br />

Location<br />

Venue Lecture Centre of the Vienna General Hospital<br />

Exhibition Areas Level 7 and Level 8<br />

Address Währinger Gürtel 18-20, 1090 Vienna, Austria<br />

40


List of Sponsors, Exhibitors and Advertisers*<br />

Ärztezentrale Adressen- <strong>und</strong> Drucksortenverlag, Vienna, Austria<br />

Abd Serotec- Endeavour House, Oxon, United Kingdom<br />

Acris Antibodies, Hiddenhausen, Germany<br />

Active Motif Europe, Rixensart, Belgium<br />

Aesca Pharma, Traiskirchen, Austria<br />

Alk Abello Allergie – Service GmbH, Linz, Austria<br />

Allergopharma, Vienna, Austria<br />

AstraZeneca Österreich, Vienna, Austria<br />

Becton Dickinson Austria, Schwechat, Austria<br />

Bencard Allergie, Vienna, Austria<br />

Bender Medsystems, Vienna, Austria<br />

Biomedica, Vienna, Austria<br />

Bio-Rad Laboratories, Munich, Germany<br />

Biotest AG, Dreieich, Germany<br />

Biozym Biotech Trading, Vienna, Austria<br />

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany<br />

CellGenix Technologie Transfer, Freiburg, Germany<br />

Cell Kinetice, Lod, Israel<br />

2 nd European Congress of Immunology – ECI 2009<br />

eubio, Vienna, Austria<br />

Fermentas, St. Leon-Rot, Germany<br />

GE Healthcare Europe, Vienna, Austria<br />

Greiner Bio – One, Kremsmünster, Austria<br />

Hal Allergy, Vienna, Austria<br />

41<br />

*(as per printing date)


List of Sponsors, Exhibitors and Advertisers*<br />

Invitrogen, Karlsruhe, Germany<br />

Jackson ImmunoResearch Europe Ltd., Suffolk, United Kingdom<br />

LaVision BioTec, Bielefeld, Germany<br />

Mabtech AB, Nacka Strand, Sweden<br />

Ferdinand Menzl Medizintechnik, Vienna, Austria<br />

Miltenyi Biotec, Bergisch Gladbach, Germany<br />

NatuTec, Frankfurt am Main, Germany<br />

New England Biolabs, Frankfurt am Main, Germany<br />

Novartis Pharma, Vienna, Austria<br />

Octapharma, Lachen, Switzerland<br />

Partec, Görlitz, Germany<br />

PeproTech, Hamburg, Germany<br />

Phadia Austria, Vienna, Austria<br />

Porsche Austria<br />

ProFas, Regensburg, Germany<br />

Charles River Consulting, Sulzfeld, Germany<br />

Roche Austria, Vienna, Austria<br />

R + D Systems, Wiesbaden, Germany<br />

Siemens Medical Solutions Diagnostics, Vienna, Austria<br />

Stallergenes France, Antony Cedex, France<br />

Stemcell Technologies, Grenoble, France<br />

tebu – bio, Offenbach, Germany<br />

THP Medical Products, Vienna, Austria<br />

Werfen Austria, Vienna, Austria<br />

Wiley Blackwell, Weinheim, Germany<br />

Yakult Deutschland, Neuss Germany<br />

42<br />

*(as per printing date)


Notes<br />

Printed in Austria by: ROBIDRUCK, 1200 Vienna – www.robidruck.co.at


Das Immunglobulin in<br />

seiner natürlichen Form<br />

Natur<br />

weitergeben<br />

Zusammensetzung: 1 ml Intratect® enthält 50 mg Plasmaproteine vom Menschen, davon mind. 96 % IgG (57,2 % IgG1, 37,2 % IgG2, 3,1 % IgG3, 3,0 % IgG4). Höchstgehalt an IgA: 2 mg/ml. Hilfsstoffe: Glycin, Wasser zur<br />

Injektion. Anwendungsgebiete: Substitutionstherapie bei primären Immunmangelsyndromen, sek<strong>und</strong>ärer Hypogammaglobulinämie <strong>und</strong> rezidivierenden bakteriellen Infektionen bei CLL <strong>und</strong> multiplem Myelom,<br />

Kinder mit angeborenem AIDS <strong>und</strong> rezidivierenden Infektionen. Immunmodulation bei ITP bei Kindern oder Erwachsenen mit einem hohen Blutungsrisiko oder vor chirurgischen Eingriffen zur Korrektur der<br />

Thrombozytenzahl, Guillain-Barré-Syndrom <strong>und</strong> Kawasaki-Syndrom. Allogene Knochenmarktransplantation. Art der Anwendung, Dosierung: Intratect® wird intravenös verabreicht. Dosierung <strong>und</strong> Intervalle der<br />

Infusionen richten sich nach der Indikation. Gegenanzeigen: Überempfi ndlichkeit gegen jegliche Bestandteile des Präparates. Überempfi ndlichkeit gegen homologe Immunglobuline, insbesondere in den sehr<br />

seltenen Fällen von IgA-Mangel, wenn der Patient Antikörper gegen IgA aufweist. Spezielle Hinweise: Bestimmte schwere unerwünschte Nebenwirkungen können im Zusammenhang mit der Infusionsgeschwindigkeit<br />

stehen. Es ist die in der Gebrauchsinformation beschriebene Infusionsgeschwindigkeit zu beachten. Die Patienten müssen während der gesamten Dauer der Infusion kontrolliert <strong>und</strong> auf Symptome unerwünschter<br />

Wirkungen beobachtet werden. Bestimmte unerwünschte Nebenwirkungen können bei einer hohen Infusionsgeschwindigkeit häufi ger auftreten, bei Patienten mit Hypo- oder Agammaglobulinämie<br />

mit oder ohne IgA-Mangel, bei Patienten, die zum ersten Mal Immunglobulin vom Menschen erhalten oder, in seltenen Fällen, bei einem Wechsel des Immunglobulin-Präparates oder nach einer längeren Behandlungspause.<br />

Nebenwirkungen: Gelegentlich können Schüttelfrost, Kopfschmerzen, Fieber, Übelkeit <strong>und</strong> Erbrechen, allergische Reaktionen, niedriger Blutdruck, Gelenkschmerzen <strong>und</strong> leichte Rückenschmerzen.<br />

Selten: plötzlicher Blutdruckabfall, vorrübergehende Hautreaktionen, Anstieg des Serumkreatinin-Spiegels, akutes Nierenversagen, thromboembolische Komplikationen. In Einzelfällen: anaphylaktischer Schock,<br />

reversible aseptische Meningitis, reversible hämolytische Anämie/Hämolyse. Wechselwirkungen: Die Gabe von Immunglobulin kann <strong>für</strong> eine Dauer von mindestens 6 Wochen <strong>und</strong> bis zu 3 Monaten die Wirksamkeit<br />

von attenuierten Lebendimpfstoffen wie Masern-, Röteln-, Mumps- <strong>und</strong> Windpockenimpfstoffen beeinträchtigen. Nach der Gabe dieses Präparates ist vor der Impfung mit attenuierten Lebendimpfstoffen<br />

eine Wartezeit von 3 Monaten einzuhalten. Bei Masernimpfung kann diese Beeinträchtigung bis zu einem Jahr fortbestehen. Daher sollte bei Patienten, die Masernimpfstoff erhalten, der Antikörperstatus überprüft<br />

werden. Handelsformen: Gebrauchsfertige Lösung zur intravenösen Infusion in Durchstichfl aschen aus Glas zu 20 ml (1,0 g), 50 ml (2,5 g), 100 ml (5,0 g) <strong>und</strong> 200 ml (10,0 g).<br />

Biotest Pharma GmbH · Postfach 10 20 40 · D-63266 Dreieich · www.biotest.de<br />

Intratect_DGN.260706.indd 1 01.08.2006 11:41:20 Uhr

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!