Prameha in terms of Diabetes Mellitus, Metabolic syndrome and ...
Prameha in terms of Diabetes Mellitus, Metabolic syndrome and ...
Prameha in terms of Diabetes Mellitus, Metabolic syndrome and ...
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• Meshasr<strong>in</strong>gi (Gymmeme sylvestre (Tetz))targets several <strong>of</strong> etiological factors associatedwith diabetes, <strong>in</strong>clud<strong>in</strong>g chronic <strong>in</strong>flammation,obesity <strong>and</strong> pancreatic β-cell function.• In a study on rats with streptozotoc<strong>in</strong>-<strong>in</strong>duced diabetes, G.sylvestre treatment resulted <strong>in</strong> 30% <strong>in</strong>crease <strong>in</strong> total pancreaticweight, <strong>and</strong> a significant <strong>in</strong>crease <strong>in</strong> the number <strong>of</strong> β-cells perislet. The regenerated pancreatic tissue resulted <strong>in</strong> completecontrol <strong>of</strong> fast<strong>in</strong>g blood glucose levels with<strong>in</strong> 20-60 days.• Several cl<strong>in</strong>ical trials have demonstrated that this drug is;effective <strong>in</strong> decreas<strong>in</strong>g blood glucose, glycosylated hemoglob<strong>in</strong>,<strong>and</strong> glycosylated plasma prote<strong>in</strong>s.53
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