Programme - British Cardiovascular Society

British Cardiovascular Society Annual Scientific Conference 2-4 JuneContentsPageNew members 2General information 3Exhibition 4Committee and Affiliated Group meetings 5BCS Board and Council 6Joint committees 6BCS committees 7Abstract markers 8Affiliated groups 9Education 12Sponsorship 13Programme at a glance (Monday 2 June) 14Programme details 16Programme at a glance (Tuesday 3 June) 38Programme details 40Programme at a glance (Wednesday 4 June) 82Programme details 84First author index 96Floor plan and mapLastPage1

British Cardiovascular Society Annual Scientific Conference 2-4 JuneNew members To be introduced at the AGM 2008General informationDr D Abdel-RahmanDr F AlamgirDr M AsgariDr R AssomullDr R BanerjeeDr S BanypersadDr M BatesDr L BhallaDr P BharadwajDr R BilkuDr D BraganzaDr M BurchDr F ChenMrs C ChittyDr S ConnollyDr C CritophDr R Denton-BeaumontDr S DuckettDr J DwightDr D ElderDr A ElkingtonMr J EvangelistaDr T FairbairnDr D FrancisDr M GaballaDr C GaleDr F GaniDr M GarbiDr R GhasilProf P GrantDr T GrayDr S HaldarDr A HamiltonDr D HausenloyDr R HuggettDr M JachuckDr D JoharDr A KanojiaDr N KeenanDr K KhanDr E LeveltDr M LynchDr C MadlerDr T MajekodunmiDr M MakhariaDr I MatthewsDr E McAlindonDr C MillerDr S MofidiDr H MoorthyDr A MozidDr M MunclingerDr S MurrayDr A NatarajanDr J O'HalloranDr C O'MahonyDr A OpelDr A Owusu-AnsahDr S PageDr I PearsonDr J PittsDR R PurnellDr K RahimiDr H RahmanDr R RajaniDr A RamsewarDr W RobertsDr E J RoffeProf G RosanoDr J RuddDr C RunnettDr N SambuDr A SankaranarayananDr F SchaferDr M SchmittDr H SchneiderDr A SeedDr V SharmaDr A SimmsDr C SkeneDr L SooDr M SosinDr M S SpenceDr E SubkovasDr F SyedDr J SzygulaDr D TaliotisDr J ThambyrajahDr L ThornhillDr R TillDr A TridanteDr A VargheseDr G ViswanathanDr C YoungDr D ZamvarConferenceThe conference will be held in Manchester Central. The programme will open onMonday 2 June at 11.00 hrs and close on Wednesday 4 June at 17.00 hrs.ExhibitionThe exhibition will be held in the Exchange Auditorium and will be open from10.00 on Monday 2 June.RegistrationRegistration will take place in the entrance to the main hall. Desks will be openat the following times:Monday 2nd June 08.30-19.00Tuesday 3rd June 07.30-19.00Wednesday 4th June 07.30-16.00See the final page of this programme for a location plan of the meeting roomsand exhibition hall.Delegate badgesWhite BCS MemberRed Non memberGreen Presenter/ChairmanBlack BCS StaffYellow Sponsored symposium onlyBadges must be worn at all times to gain admission to sessions, exhibition hall,annual dinner and other events.The audiovisual centre will be located in the Exchange organisers’ office.CPD – the conference is registered with the RCP for CME/CPD.Catering facilities are located within the exhibition. For those attending the ‘How to’sessions, a packed lunch will be available for purchase.23

British Cardiovascular Society Annual Scientific Conference 2-4 JuneExhibitionCommittee and AffiliatedGroup meetingsThe Society would like to thank the many exhibitors who have purchased stand space.All delegates are encouraged to visit the exhibition, which will be open at thefollowing times:Monday 4th June 10.00-19.00Tuesday 5th June 09.00-19.00Wednesday 6th June 09.00-16.00Further information on the exhibition may be obtained by email from exhibition@bcs.comSponsored symposiaA number of companies are hosting sponsored symposia on Monday and Tuesday.Monday09.00-10.30CV Therapeutics – Clinical implications of the inhibition of the late sodium current. A newparadigm in the treatment of ischaemic heart disease.18.30-20.00Servier Laboratories Ltd – On the pulse of CV risk prevention.18.30-20.00Merck, Sharp & Dohme Ltd – Lipids On Trial – Is UK lipid management placing too muchemphasis upon LDL management and not fully considering other lipid parameters implicatedin CV risk?Tuesday18.00-19.30Daiichi-Sankyo & Eli Lilly – ACS-PCI: Anti-platelet therapy – controversy or consensus?18.00-19.30AstraZeneca – Managing the increasing burden of cardiovascular risk.Monday 2 JuneCommittee Room TimeClinical Standards Committee Exhibit 1 08.30-09.30SAC – TPD Meeting Exchange 1 14.00-15.30Trainee Education – TPD Meeting Exchange 1 15.30-16.00British Cardiovascular Intervention Society (BCIS) Exchange 4 15.30-16.30Society for Cardiological Science and Technology(SCST) – Council Exchange 5 15.30-16.30KBA Exchange 6 15.30-16.30British Nuclear Cardiology Society (BNCS) Exhibit 1 15.30-16.30British Junior Cardiologists’ Association (BJCA) Exhibit 2 15.30-16.30Women in UK Cardiology Network Exchange 2 15.30-16.30British Society of Echocardiography (BSE) Industry Exchange 7 15.30-16.30Tuesday 3 JuneCommittee Room TimeArrhythmia Alliance (AA) Exchange 4 07.00-08.45British Congenital Cardiac Association (BCCA) Exhibit 2 07.00-08.45British Society for Cardiac Research (BSCR) Exchange 4 10.15-11.15British Society of Echocardiography (BSE) Exchange 5 10.15-11.15Heart Care Partnership UK (HCP(UK)) Exchange 6 10.15-11.15Academic and Research Committee Exchange 7 10.15-11.15Trainee Education Working Group Exhibit 2 10.15-11.15British Association for Cardiac Rehabilitation (BACR) Exchange 4 15.30-16.30CAA Approved Cardiologists’ Meeting Exchange 5 15.30-16.30Information and Surveys Committee Exchange 6 15.30-16.30Working Group for Women’s Heart Health Exhibit 2 15.30-16.30Wednesday 4 JuneCommittee Room TimeHeart Rhythm UK (HR (UK)) Exchange 4 07.00-08.45Society for Cardiological Science and Technology(SCST) – Education Exchange 4 09.45-10.45Guidelines and Practice Committee Exhibit 1 09.45-10.4545

British Cardiovascular Society Annual Scientific Conference 2-4 JuneBCS Board and CouncilBCS committeesBoard Position AppointedDr Nicholas Boon President 2007-2010Dr Stephen Holmberg Honorary Secretary 2006-2008Dr Charles Knight Honorary Secretary Elect 2007-2008Dr David Hackett VP Clinical Standards 2007-2010Dr Kevin Jennings VP Corporate and Financial Affairs 2006-2009Prof David Crossman VP Education and Research 2003-2008Prof Stuart Cobbe VP Training 2007-2009Dr Iain Simpson VP Education and Research 2007-2008Prof Dame Carol Black Non-executive Trustee 2007-2011Mr Graham Meek Non-executive Trustee 2007-2011Council MembersRoger BoyleWilliam BrawnChris BurrellKeith ChannonChris CloughStuart CobbeMartin CowieDavid CrossmanMark De BelderPatrick DohertyChris EggettDavid EisnerJane FlintAlan FraserChris GaleDavid GeldardPeter GrovesJim HallTrudie LobbanTerry McCormackAndrew McLeodGraeme McNeillCharles PeeblesDudley PennellJoint committeesHeart Management (BCS/BMJ Publishing)Nicholas Boon (President, BCS, Co-Chair)Stella Dutton (Chief Executive Officer, BMJPG, Co-Chair)Joint Specialty Committee for CardiologyDavid Crossman (Chair)Specialty Advisory Committee (RCP/BCS)Stuart Cobbe (Chair)Simon RayEdward RowlandJames RoxburghMark SignyDeclan SugrueJenny TagneyAdam TimmisNeal UrenSimon WoldmanPeter WeissbergAcademic and ResearchHugh Watkins (Chair)Nicholas BoonRobin ChoudhuryDavid CrossmanDavid EisnerAdam FitzpatrickKevin JenningsMichael MarberNilesh SamaniPeter WeissbergWojtek TrzcinskiClinical Standards –In preparationDavid Hackett (Chair)Elections and NominationsNicholas Brooks (Chair)Jennifer AdgeyNicholas BoonJohn CammHuon GrayDavid GeldardCharles GeorgeStephen HolmbergHoward SwantonAnna KassaiSteven YeatsFinanceKevin Jennings (Chair)Nicholas BoonIan HuttonNicholas KayeGraham MeekPaul OldershawMartin RothmanTony SalterDerek YellonWojtek TrzcinskiSteven YeatsGuidelines and PracticeAdrian Brady (Chair)Nicholas BoonSteven BridgeStuart CobbeDavid HackettGuy HaywoodTerry McCormackKen TimmisKirsten BradburyIndustry LiaisonNicholas Boon (Chair)Chris BrinsmeadNigel BrooksbyStephen BrownEric FalcandJackie GanleyDavid GeldardBeccy HolmbergKevin JenningsGeoff MorrisAnthony MourantSatoru NoguchiPeter WeissbergAnthony WhiteheadDerek YellonSteven YeatsCommunication andEducation (formerly knownas Information and Surveys)Sarah Clarke (Chair)Tim BowkerIan CoxChris GaleMartin GodfreyStephen HolmbergCharles KnightConrad MurphyStuart PringleDavid RobertsKirsten BradburyDilowar HussainAnna KassaiSteven YeatsProgrammeDavid Crossman (Chair)George BarnesMartin BennettNicholas BoonBarbara CasadeiSarah ClarkeStuart CobbeAnthony GershlickDavid HackettStephen HolmbergKevin JenningsCharles KnightJeremy PearsonBernard PrendergastIain SimpsonDerek YellonMary-Lou PittsSteven Yeats67

British Cardiovascular Society Annual Scientific Conference 2-4 JuneAbstract markersAffiliated groupsThe Programme Committee wishes to acknowledge the generous help given in abstractselection by the following (names in bold indicate Chairmen of the markers for their category).Dr Abdallah Al-MohammedDr Felicity AstinDr Ameet BakhaiDr Adrian BanningDr Khalid BarakatDr Andreas BaumbachProf Harald BecherDr Tim BettsProf Shoumo BhattacharyaDr Andrew BishopDr Richard BogleDr Nick BoonDr John BourkeDr Adrian BradyDr Carl BrookesProf Morris BrownDr Frances Bu’lockDr Alison CalverProf David CarlingDr John ChambersDr Robert ClarkeProf Keiran ClarkeDr Peter CowburnDr Tim CrippsDr Piers DaubeneyDr George Davey-SmithDr Wyn DaviesDr Dana DawsonDr Mark de BelderProf Christopher DeatonDr Catherine DickinsonDr Clare DolleryProf Anna DominiczakDr David DutkaMs Linda EdmundsDr Martyn FarrerDr Albert FerroDr Darrel FrancisDr Paul FraserDr Steve FurnissDr Michael GammageProf Cliff GarrattDr Mathias GautelDr Fiona GreenDr John GreenwoodDr Mike GriffithDr Mark GunningDr Harry HemingwayDr Rob HendersonDr Deborah HendersonDr Mark KearneyDr Bernard KeavneyDr Peter KohlProf Chim LangDr Guy LloydDr Peter LudmanDr Philip MacCarthyDr Kenneth MacLeodProf Giovanni MannDr Vias MarkidesDr Anthony MathurDr Jamil MayetDr Bongani MayosiDr Jean McEwanDr Patricia MunroeProf Leong NgDr Nikhil PatelDr Charles PeeblesDr Denis PellerinProf Dudley PennellDr Bernard PrendergastMr Praksh PunjabiDr Ian PurcellProf Tom QuinnProf Tom QuinnDr Simon RayDr Simon RedwoodDr Charles RedwoodDr Adrian RozkovecDr Naveed SattarDr MichaelaScheuermann-FreestoneDr Richard SchillingDr Roxy SeniorDr Len ShapiroDr Alistair SladeDr David SprigingsDr Adrian StanleyDr Richard SteedsDr Alan StruthersDr Graham StuartMs Jenny TagneyDr Bun TanDr Sara ThorneDr Jonathan TownendDr Victor TsangDr Robert TullohDr Hannah WaterhouseDr Nick WestProf Martin WilkinsDr Simon WilliamsDr Simon WoldmanDr Christopher WrenMs Martha WrighleyDr Qingbo XuArrhythmia Alliance (A-A)President:Prof John Camm (jcamm@sghms.ac.uk)Treasurer:Charles Lobban (charles@stars.org.uk)Secretary:Adam Fitzpatrick (c/o trudie@stars.org.uk)British Association for Cardiac Rehabilitation (BACR)President:Prof Patrick Doherty (p.doherty@yorksj.ac.uk)Treasurer:Mrs Linda Edmunds (linda.edmunds@cardiffandvale.wales.nhs.uk)Secretary:Miss Gill Fitnum (gillian.fitnum@bromleyhospitals.nhs.uk)British Association for Nursing in Cardiovascular Care (BANCC)President:Ms Jenny Tagney (jenny.tagney@ubht.nhs.uk)Treasurer:Mr Sanjay Ramdany (sanjay.ramdany@bartsandthelondon.nhs.uk)Secretary:Mrs Jane Butler (jane.butler@bartsandthelondon.nhs.uk)British Atherosclerosis Society (BAS)Chairman:Prof Keith Channon (keith.channon@cardiov.ox.ac.uk)Treasurer:Dr Chris Newman (c.newman@sheffield.ac.uk)Secretary:Dr Sarah George (s.j.george@bristol.ac.uk)British Congenital Cardiac Association (BCCA)President:Dr William Brawn (william.brawn@bch.nhs.uk)Treasurer:Dr Joseph De Giovanni (degiovanni@blueyonder.co.uk)Secretary:Dr Graham Stuart (agstuart@blueyonder.co.uk)British Cardiovascular Intervention Society (BCIS)President:Dr Mark de Belder (mark.debelder@stees.nhs.uk)Treasurer:Dr Simon Redwood (simon.redwood@gstt.sthames.nhs.uk)Secretary:Dr Bernard Prendergast (bernard.prendergast@smuht.nwest.nhs.uk)89

British Cardiovascular Society Annual Scientific Conference 2-4 JuneAffiliated groups continuedBritish Junior Cardiologists’ Association (BJCA)President:Dr Chris Gale (c.p.gale@leeds.ac.uk)Treasurer:No appointmentSecretary:Dr Damian Kelly (djskelly@btinternet.com)British Society for Heart Failure (BSH)Chairman:Prof Martin Cowie (m.cowie@imperial.ac.uk)Treasurer:Dr Suzanna Hardman (suzanna.hardman@whittington.nhs.uk)Secretary:Ms Michelle Glanville (info@bsh.org.uk)British Nuclear Cardiology Society (BNCS)President:Dr Simon Woldman (simon.woldman@uclh.nhs.uk)Treasurer:Dr Catherine Dickinson (catherine.dickinson@leedsth.nhs.uk)Secretary:Dr Parthiban Arumugan (parthiban.arumugan@cmmc.nhs.uk)Heart Care Partnership UK (HCP(UK))Chairman:Mr David Geldard (david.geldard2@ntlworld.com)Treasurer:Mr Ken Timmis (kenneth.timmis@blueyonder.co.uk)Secretary:Mrs Anne Jolly (sadsuk@btconnect.com)British Society of Cardiovascular Imaging (BSCI)Chairman:Dr Charles Peebles (charles.peebles@suht.swest.nhs.uk)Treasurer:Dr Richard Coulden (rc@prdg.demon.co.uk)Secretary:Dr Roger Bury (rogerwbury@btinternet.com)Heart Rhythm UK (HRUK)President:Dr Edward Rowland (erowland@sgul.ac.uk)Treasurer:Prof John Morgan (jmm@hrclinic.org)Secretary:Dr Michael Gammage (m.d.gammage@bham.ac.uk)British Society of Cardiovascular Magnetic Resonance (BSCMR)President:Prof Dudley Pennell (d.pennel@imperial.ac.uk)Treasurer:Prof Henry Dargie (h.dargie@bio.gla.ac.uk)Secretary:Mrs Michelle Glanville, BSCMR Secretariat (office@bscmr.org)British Society for Cardiovascular Research (BSCR)Chairman:Prof David Eisner (eisner@man.ac.uk)Treasurer:Dr Michael J Curtis (michael.curtis@kcl.ac.uk)Secretary:Prof Barbara McDermott (b.mcdermott@qub.ac.uk)British Society of Echocardiography (BSE)President:Dr Simon Ray (simon.ray@smuht.nwest.nhs.uk)Treasurer:Mr Graham Leech (graham@cardiac.demon.co.uk)Secretary:Mrs Jane Allen (jane.allen@york.nhs.uk)Primary Care Cardiovascular Society (PCCS)Chairman:Dr Terry McCormack (tesmcc@aol.com)Chairman-Elect: Dr Ahmet Fuat (a.fuat@ntlworld.com)Treasurer:Dr Stewart Findlay (stewart.findlay@durhamdalespct.nhs.uk)Secretary:Dr Kathryn Griffith (kathryn.griffith@york.nhs.uk)Executive Director: Dr Fran Sivers (fransivers@pccs.org.uk)Society for Cardiological Science and Technology (SCST)President:Dr Chris Eggett (chris.eggett@suntpct.nhs.uk)Treasurer:Dr Leslie Goulding (l.goulding858@btinternet.com)Secretary:Mr Peter Lewis (peter.lewis@nglam-tr.wales.nhs.uk)1011

British Cardiovascular Society Annual Scientific Conference 2-4 JuneEducationEducation in the ExhibitionThe Society wishes to draw your attention to educational activities which are being held inthe Exhibition.Daiichi-Sankyo – Stand 246DAIICHI-SANKYO is pleased to provide a Med Info zone to delegates at the BCS AnnualScientific Conference to answer those queries that you keep meaning to ask but neverget the chance during the ‘day job’. In particular, if you have a questions about ourcommitment to the ACS, hypertension and diabetes therapy areas, then our team,on stand number 246 will be happy to help.Radi Medical Systems – Stand 6Radi Medical Systems will deliver short teaching sessions on Stand 6 (beside the mainentrance) in the Exhibition Hall at the following times:Monday 2nd June 16.00Tuesday 3rd June 10.30 and 16.00Wednesday 4th June 10.00 and 13.00Topics will include “FFR Waveform Diagnostics and Troubleshooting”, “FFR in complexdisease”, “Advanced Wireless Technology”, “FFR in a busy cath. lab.” and will providean opportunity for questions and answers. We encourage all delegates to attend thesesessions especially those who are new or relatively new to the concept of measuringFractional Flow Reserve.There will also be the opportunity to discuss the rationale and design of the FFR versusAngiography for Multivessel Evaluation (FAME) study.A number of small prizes (from an ipod to umbrellas!) will be presented to attendingdelegates who are successful in entering our exhibition draw.PCI Simulator Training for Specialist RegistrarsSimulator training sessions in percutaneous coronary intervention will be available forspecialist registrars at this year's Annual Scientific Conference.Throughout the day on both Monday and Tuesday, simulators will be available to practicea range of interventional techniques including trans-radial interventions and bifurcations.On both days, 40 minute supervised individual training sessions will be available whichneed to be booked in advance through the BCS website on a first come, first served basis,so book early to avoid disappointment.The British Cardiovascular Society is grateful to Terumo, Boston Scientific and Cordis formaking this educational opportunity possible.Novartis – Stand 358Novartis are pleased to announce that short training sessions using the Harvey mannequinpatient simulator will be conducted on stand 358 during the following times:Monday 2nd June 13.00-14.00; 15.30-16.30Tuesday 3rd June 10.15-11.15; 15.30-16.30Wednesday 4th June 09.45-10.45; 12.30-13.30; 15.00-16.00Spaces are limited and will be allocated on a first come, first served basis.The Harvey mannequin patient simulator will also feature in the session‘How to examine the heart’ held in the exhibition hall on Tuesday 3 June at 13.00.BCS LectureOn Sunday 1st June, the British Cardiovascular Society is pleased to announce a publiclecture to be given by Professor Sir Bruce Keogh.The subject of the lecture will be the NHS and it will be held at 5.00pm in ManchesterCentral, in the main auditorium.There will also be an art competition with the subject of ‘The Heart’ that will be exhibitedby local schools in the foyer.SponsorshipA number of companies are hosting sponsored symposia on Tuesday and Wednesdaylunchtimes and Tuesday evening.The Society is pleased to announce that there will be free WiFi available throughout theManchester Central Exhibition Hall for the duration of the conference. This service isprovided by Daiichi-Sankyo & Eli Lilly.To receive a free username and password, which is valid for 1 day, please visit theDaiichi-Sankyo & Eli Lilly stand (No 120). A new access token can be collected fromthe stand on each day of the exhibition.The Society also wishes to thank Sanofi Aventis for sponsorship which has been usedto support the activities of delegates attending the meeting.1213

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme at a glanceMonday 2 June9.0010.0011.0011.15Exchange AuditoriumSponsored SymposiaCV TherapeuticsEurope LtdOpening CeremonyBCCA/BCISHoles, tunnels and leaksExchange Hall Charter 3-5 Charter 1 Charter 2 Exchange 1Meet the SACExhibition OpensBSCMR/BASCMR in CHDBSH/BNCS/BSEInvestigations in heart failure:tracking changing prognosis andtailoring therapyExhibition OpensBSCRUnstable Plaque:To Inflammation and BeyondProgramme at a glanceMonday 2 June12.4513.00In Exhibition HallHow to programme apacemaker or AICD deviceExhibition BreakIn Exhibition HallHow to interact with thelegal professionExhibition BreakHow to use murinemagnetic resonance14.00BCS/ACCCardiac risk in athletesTeach InHRUKEmergency management ofarrhythmiasBSH/HCPUK/BCCACardiovascular aspects ofpregnancyBSE/BSCMR/BNCS/BSCIMultimodality imagingcase demonstrationand interactionBSCRTargeting acute and chronicremodelling post-myocardialinfarction15.30Exhibition BreakExhibition Break16.30BCS/RCP LectureJoy Edelman Legacy17.30BCS and BSCR Posters in Exhibition(35-122)BCS and BSCR Posters in Exhibition(35-122)18.30Sponsored SymposiaServier Laboratories LtdSponsored SymposiaMerck Sharpe & Dohme20.00Heart Failure Electrophysiology/pacing Intervention Imaging1415

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeMain Hall Entrance 08.30-19.00RegistrationExchange Auditorium 09.00-10.30Sponsored SymposiumCV Therapeutics Europe LtdClinical Implications of the inhibition of the late sodium current. A new paradigm in thetreatment of ischaemic heart disease.Chairs: Prof John Camm and Prof Robert WilcoxWelcome and introductonProf John CammChronic stable angina: a benign condition or requiring aggressive managementProf Robert WilcoxThe role of the late sodium current as a new target in ischaemic heart diseaseProf John CammThe clinical management of ischaemic heart disease and diabetesDr Mark KearneyInequity in the management of angina – it’s unfair but does it matter?Prof Adam TimmisConclusions and summaryProf Robert WilcoxExhibition Opens 10.00Exchange Auditorium 11.15-12.45British Congenital Cardiac Association (BCCA)British Cardiovascular Intervention Society (BCIS)Holes, tunnels and leaks; technology, technique and governanceChairs: Dr David Hildick-Smith and Dr Brodie KnightASD/PFODr Michael MullenVSDDr Rob MartinAortic shunts/Sinus of ValsalvaDr Kevin WalshParavalvar leaksDr Joseph De GiovanniDebate: Who should perform interventions for congenital/structural lesions?Pro Paediatric cardiologist: Dr John GibbsPro Adult cardiologist: Dr Martyn Thomas16Exchange Hall 11.15-12.45SAC ProgrammeChair: Prof Stuart CobbeMMC and the Tooke EnquiryProf Stuart CobbeTrainees assessmentsDr Ian Wilsone-portfolio and Knowledge Based AssessmentDr Jim HallQuestions and answersCharter 3-5 11.15-12.45British Society of Cardiovascular Magnetic Resonance (BSCMR)British Atherosclerosis Society (BAS)Cardiovascular magnetic resonance for the assessment of coronary heart diseaseChairs: Prof Henry Dargie and Prof Keith ChannonPathophysiology of coronary heart disease – the case for multi-parametric imagingProf Michael FrenneauxCMR of patients with stable chest painProf Eike NagelAssessment of acute coronary syndromes with CMRDr Sven PleinAssessment of arterial wall volume and functionProf Dudley PennellAtherosclerotic plaque and molecular imagingDr Robin Choudhury17Programme at a glanceMonday 2 June

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeCharter 1 11.15-12.45British Society for Heart Failure (BSH)British Nuclear Cardiology Society (BNCS)British Society of Echocardiography (BSE)Investigations in heart failure: tracking changing prognosis and tailoring therapyChairs: Prof John Cleland and Dr Andrew KelionBiomarkers from blood testsDr Roy GardnerEchocardiographyDr Simon RayNuclear techniquesDr Alexander JacobsenMagnetic resonanceDr Sanjay PrasadCharter 2 11.15-12.45British Society for Cardiovascular Research (BSCR)Unstable Plaque: To Inflammation and BeyondChairs: Dr Cathy Holt and Dr Chris JacksonInflammatory mediators and plaque destabilizationProf Erik BiessenBiomarkers of inflammationProf Juan Carlos KaskiChemokines as therapeutic targets in plaque ruptureDr David GraingerC-reactive protein and plaque stabilityProf Mark PepysExhibition Break 12.45-13.00Exhibition Hall 13.00-14.00How to programme a pacemaker and AICDChair: Dr Simon FynnHow to program a pacemakerDr Tim BettsHow to program an AICDDr Neil DavidsonExhibition Hall 13.00-14.00How to interact with the legal professionChair: Prof Roger HallPreparing a reportDr Stephen SaltissiGiving evidenceDr Michael PetchExchange 1 13.00-14.00How to use murine magnetic resonanceChair: Prof Rene BotnarImaging the mouse heart with MRDr Jurgen SchneiderCardiac metabolismDr Anne-Marie SeymourVascular and molecular studiesDr Robin ChoudhuryExchange Auditorium 14.00-15.30British Cardiovascular Society (BSC)American College of Cardiology (ACC)Cardiac risk in athletesChairs: Prof James Dove and Prof William McKennaArrhythmic death in athletes: Lessons from genes and animal modelsProf Carlo NapolitanoExercise-induced cardiac hypertrophy: is it really different?Dr Cam PattersonCardiac pathophysiology of elite athletesDr Sanjay SharmaPrevention of sudden death in athletes: the power of screeningProf Domenico CorradoProgramme at a glanceMonday 2 June1819

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeExchange Hall 14.00-15.30Teach inHeart Rhythm UK (HRUK)Emergency management of arrhythmiasChairs: Dr Richard Schilling and Dr Tim BettsAcute management of atrial fibrillation and flutterDr Mark EarleyTreatment of VT stormDr Simon SportonWho needs temporary pacing, and how to do it?Dr Kim RajappanCharter 3-5 14.00-15.30British Congenital Cardiac Association (BCCA)British Society for Heart Failure (BSH)Heart Care Partnership UK (HCP UK)Cardiovascular aspects of pregnancyChairs: Dr Jane Flint and Prof John ClelandPre-conception adviceDr Dawn AdamsonManaging pulmonary hypertension in pregnancyDr Sarah ThorneRecent developments in postpartum cardiomyopathyProf Denise HilfikerA personal perspective of post-partum cardiomyopathyMs Susan SneddonLate cardiovascular complications of pre-eclampsiaProf Jill PellCharter 1 14.00-15.30British Society of Echocardiology (BSE)British Nuclear Cardiology Society (BNCS)British Society of Cardiovascular Magnetic Resonance (BSCMR)British Society of Cardiovascular Imaging (BSCI)Multimodality imaging case demonstration and interactionChair: Dr Rick Steeds and PanelEchocardiographyDr Rick SteedsCMRDr Raad MohiaddinCT/radiologyDr James RuddNuclear cardiologyDr Ashley GrovesPanel discussionCharter 2 14.00-15.30British Society for Cardiovascular Research (BSCR)Targeting acute and chronic remodelling post-myocardial infarctionChairs: Dr Gillian Gray and Dr Nicola KingCardiac remodelling – mechanisms and clinical implicationsProf Allan StruthersThymosin‚ ß4, angiogenesis and cardiac remodellingDr Nicola SmartRole of aldosterone in acute and chronic cardiac remodellingProf Dr Johann BauersachsReversing cardiac remodelling in the failing heartDr Emma BirksExhibition Break 15.30-16.30Programme at a glanceMonday 2 June2021

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeExchange Auditorium 16.30-17.30British Cardiovascular Society (BCS)Royal College of Physicians (RCP)British Cardiovascular Society Lecture supported by the Joy Edelman legacyUnderstanding the genetic basis of coronary artery disease – an achievable goal?Prof Nilesh SamaniIntroduced by: Dr Michael CheshireThanked by: Prof Hugh WatkinsExhibition Hall 17.30-19.00BCS and BSCR Posters035IMPLANTABLE CARDIOVERTER DEFIBRILLATORS FOR PRIMARY PREVENTIONFOLLOWING A MYOCARDIAL INFARCTION: A DISTRICT GENERAL HOSPITALPERSPECTIVEAddison, C1; Foley, P2; Ratib, K1; Patel, K3; Smith, R2; Leyva, F21. Good Hope Hospital, Heart of England NHS Foundation Trust; 2. Good Hope Hospital, University ofBirmingham, Heart of England NHS Foundation Trust; 3. Sandwell Hospital, University of Birmingham036AWARENESS OF CONTRAST NEPHROPATHY AT ROYAL BROMPTON HOSPITALAND EFFECTIVENESS OF MEASURES USED TO DETECT ITAinslie, M; Schultz, C; Davies, SRoyal Brompton037EFFECT OF METFORMIN ON MORTALITY AND HOSPITALIZATIONS IN PATIENTS WITHHEART FAILURE AND TYPE 2 DIABETESAlzadjali, M; Ogston, S; Evans, J; Doney, A; Khan, F; Morris, A; Struthers, A; Lang, CUniversity of Dundee038ADDITION OF B-TYPE NATRIURETIC PEPTIDE TO THE GLOBAL REGISTRY OF ACUTECORONARY EVENTS (GRACE) SCORE ENHANCES RISK STRATIFICATION IN ACUTECORONARY SYNDROMEAng, D; Wei, L; Lang, C; Struthers, AUniversity of Dundee039ADDITION OF B-TYPE NATRIURETIC PEPTIDE TO THE THROMBOLYISIS INMYOCARDIAL INFARCTION (TIMI) RISK SCORE ENHANCES RISK STRATIFICATIONIN ACUTE CORONARY SYNDROMEAng, D; Wei, L; Lang, C; Struthers, AUniversity of Dundee040BIVALIRUDIN IN REAL WORLD PCI: DOES UK EXPERIENCE IN TROPONIN-POSITIVEACUTE CORONARY SYNDROMES MATCH UP TO ACUITY?Augustine, D1; Khan, Z1; Chamberlain-Webber, R1; West, N21. Gloucestershire Hospitals NHS Foundation Trust; 2. Papworth Hospital041THE PREVALENCE OF ABSOLUTE AND RELATIVE CONTRAINDICATIONS TO STATINTHERAPY FOLLOWING ACUTE CORONARY SYNDROMEBailey, K1; Space Rocket Investigators, T21. Leeds University; 2. NHS042ASSESSMENT OF PCI PRACTICE? RESULTS OF A NETWORK-WIDE PEER REVIEWAUDIT ASSESSMENTBehan, M; Dixon, G; Blows, L; Hildick-Smith, D; Holmberg, S; deBelder, ASussex Cardiac Centre043THE EXPERIENCE OF CARDIAC CHANNELOPATHIES AT A TERTIARY REFERRALCENTRE IN NORTHERN IRELANDBennett, J; McOsker, J; Jardine, T; Scott, P; Murphy, J; McKeown, PRoyal Victoria Hospital, Regional Medical Cardiology Centre044CORONARY ARTERY REMODELING IS ASSOCIATED WITH LONG-TERMCARDIOVASCULAR PROGNOSISBerry, C1; Noble, S2; L’Allier, P2; Gregoire, J2; Lesperance, J2; Levesque, S2;Ibrahim, R2; Tardif, J21. BHF Glasgow Cardiovascular Research Centre; 2. Montreal Heart InstituteProgramme at a glanceMonday 2 June2223

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme045RE-PROCESSING ELECTROPHYSIOLOGY CATHETERSBowater, S; Jones, D; Flannigan, S; Marshall, H; Griffith, MQueen Elizabeth Hospital046THE EFFECTS OF CLINIC STYLE ON ACCESS RATES TO CATHETER ABLATIONIN THE MIDLANDSBowater, S1; Tapp, L2; Price, A1; Marshall, H1; Prasad, N3; Glancy, J3; Griffith, M11. Queen Elizabeth Hospital; 2. Good Hope Hospital; 3. Hereford County Hospital047FEMORAL VASCULAR ACCESS COMPLICATIONS IN ADULT CONGENITAL HEARTDISEASE PATIENTS: AUDIT FROM A SINGLE TERTIARY CENTREChue, C1; Hudmsith, L1; Stumper, O2; De Giovanni, J2; Thorne, S1; Clift, P11. Queen Elizabeth Hospital Birmingham; 2. Birmingham Children’s Hospital048PALPITATIONS AND PSYCHOLOGICAL MORBIDITYCooke, J1; Shiner, A2; Sandler, D1; O’Toole, L31. Chesterfield Royal Hospital Foundation Trust; 2. Derbyshire County PCT; 3. Royal Hallamshire Hospital049CLINICAL ACUMEN AND THE TREADMILL IN THE RAPID ACCSS CHEST PAIN CLINIC– CAN WE DO BETTER ? SIGNIFICANT MAJOR ADVERSE CARDIAC EVENT RATEAT 1 YEAR FOLLOW UP IN PATIENTS DISCHARGED TO THEIR GPDorman, S; Barry, J; Jeetley, P; Nightingale, AUnited Bristol Healthcare Trust050LIPID-LOWERING WITH SIMVASTATIN 40MG FOLLOWING ACUTE CORONARYSYNDROMES ACHIEVES NATIONAL NSF/GMS AUDIT STANDARDS BUT NOTJBS2 TARGETS FOR SECONDARY PREVENTIONDorman, S1; Johnson, T2; West, N31. United Bristol Healthcare Trust; 2. Swindon and Marlborough NHS Trust; 3. Papworth Hospital NHS Trust051HIGH PREVALENCE OF ABNORMAL GLUCOSE METABOLISM IN PATIENTSPRESENTING FOR ROUTINE CORONARY ANGIOGRAPHYEnglish, C; Hastings, J; Dineen, S; Daly, K; Nash, P; Crowley, JUniversity College Hospital, Galway052CABG AND PCI FOR LEFT MAIN STEM CORONARY ARTERY DISEASE:SYNERGY IN A REAL WORLD REGISTRYGunn, J1; Briffa, N21. University of Sheffield; 2. Northern General Hospital053AUDIT OF CONTRACEPTION ADVICE IN WOMEN WITH HEART DISEASE:WHERE ARE WE GOING WRONG?Aston, S; Hudsmith, L; Bowater, S; Steadman, C; Clift, P; Thorne, SQueen Elizabeth Hospital054ELECTIVE CARDIOVERSION UNDER CONSCIOUS SEDATION: SIX YEAR EXPERIENCEOF MORE THAN 2000 PROCEDURES.Jeilan, M1; Tuan, J2; Kundu, S2; Osman, F2; Mantravadi, R2; Pathmanathan, R2;Toff, W2; Ng, G21. Glenfield; 2. Glenfield Hospital055ACCURACY OF AMBULANCE STAFF DIAGNOSIS OF ACUTE CARDIOGENICPULMONARY OEDEMA: A PROSPECTIVE DIAGNOSTIC STUDY OF 1,334 PATIENTSJenkinson, E1; Woollard, M2; Robertson-Steel, I3; Newcombe, R41. (Previously) Heartlands Hospital/West Midlands Ambulance Service; 2. Faculty of Pre-hospital CareResearch Unit; 3. West Midlands Ambulance Service; 4. University of Cardiff056IMPLANTABLE CARDIOVERTER DEFIBRILLATOR (ICD) IMPLANTATIONIN NORTHWEST LONDON: AN AUDIT OF NICE GUIDELINE ADHERENCEKoa-Wing, M1; Gardner, C2; Schonfield, S3; Davies, D1; Peters, N1; Kanagaratnam, P11. Imperial College Healthcare NHS Trust; 2. The Audit, Information and Analysis Unit for London, Kent,Surrey and Sussex; 3. Specialised Services Commissioning NW London, Hillingdon Primary Care TrustProgramme at a glanceMonday 2 June2425

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme057EUROASPIRE III: LIFESTYLE AND RISK FACTOR MANAGEMENT AND USE OF DRUGTHERAPIES IN CORONARY PATIENTS FROM 22 COUNTRIES IN EUROPEKotseva, K1; Jennings, C1; De Bacquer, D2; De Backer, G2; Keil, U3; Wood, D11. NHLI, Imperial College London; 2. University of Ghent; 3. University of Munster058CLINICAL REALITY OF CORONARY PREVENTION IN EUROPE: A COMPARISONOF EUROASPIRE I, II AND III SURVEYSKotseva, K1; Jennings, C1; De Bacquer, D2; De Backer, G2; Keil, U3; Wood, D11. NHLI, Imperial College London; 2. University of Ghent; 3. University of Munster059EXTERNAL VALIDATION OF ESTABLISHED RISK ADJUSTMENT MODELS FORPROCEDURAL COMPLICATIONS AFTER PERCUTANEOUS CORONARYINTERVENTION ON AN INDEPENDENT DATA SET IN A UK SETTINGKunadian, B; Dunning, J; Das, R; Roberts, A; Morley, R; Turley, A; Twomey, D; Hall, J;Wright, R; Sutton, A; Muir, D; de Belder, MThe James Cook University Hospital063LEFT VENTRICULAR IMPAIRMENT AND LONG-TERM MORTALITY FROM ACUTECORONARY SYNDROMES: ANALYSIS BY HAEMOGLOBIN CONCENTRATIONRamachandra, R1; Dudley, F2; Batin, P3; Wilson, I3; Gale, C41. Bradford Royal Infirmary; 2. Pinderfields General Infirmary; 3. Pinderfields General Hospital;4. University of Leeds064PATIENTS WITH METABOLIC SYNDROME PRESENT WITH NON-ST ELEVATIONMYOCARDIAL INFARCTION AT A YOUNGER AGE AND HAVE WORSEANGIOGRAPHIC FINDINGSRao, G; Noronha, B; Innasimuthu, A; Davis, GUniversity Hospital Aintree065CLINICAL OUTCOMES IN PRE-HOSPITAL THROMBOLYSIS IN A RURAL SETTINGSalahshouri, P1; McCormick, L1; Murray, P2; Khan, S1; Scott, J3; Sharples, L4; Schofield, P11. Papworth NHS Trust; 2. East Anglian Ambulance Trust; 3. East of England Ambulance NHS Trust;4. MRC Biostatistics UnitProgramme at a glanceMonday 2 June060CHANGES IN THE USE OF DRUG ELUTING STENTS FOR PERCUTANEOUSCORONARY INTERVENTIONNadar, S; Varma, C; Millane, T; Lip, G; Watson, RCity Hospital066IS RATE OR REGULARITY THE MORE IMPORTANT RISK PREDICTORIN POST-MYOCARDIAL INFARCTION ATRIAL FIBRILLATION?Sankaranarayanan, R1; James, M2; Gonna, H2; Burtchaell, S2; Holloway, R21. Royal Blackburn Hospital; 2. Taunton and Somerset Hospital061ADVERSE RISK PROFILE AND MANAGEMENT DELAYS IN PATIENTS WITHOUTA DIAGNOSTIC EXERCISE TEST ? LIMITATIONS OF THE RAPID ACCESS CHESTPAIN SERVICE MODELNair, B; Hamid, T; Chacko, S; Turkie, W; Diab, I; Arumugam, P; Khattar, RManchester Royal Infirmary062IMPACT OF THE JBS2 GUIDELINES ON THE SUCCESS OF REACHING TARGETIN PATIENTS ON LIPID LOWERING STATIN THERAPYPatel, M1; Nadra, I21. Highfield Surgery; 2. Hammersmith Hospital, Imperial College Healthcare NHS Trust067APPROPRIATENESS ASSESSMENT OF CARDIAC MRI UTILISATION AND THE ROLEOF VIABILITY IMAGING IN THE PATIENT CARE ALGORITHMSchmitt, M; Das, D; McCann, GGlenfield Hospital068DECLINING LIPID LEVELS IN PATIENTS ADMITTED WITH MYOCARDIAL INFARCTIONTO A REGIONAL CARDIOLOGY CENTRE 2000-2006Scott, P; Kodoth, V; Noad, R; Bennet, J; Murphy, J; Manoharan, G; Adgey, ARoyal Victoria Hospital2627

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme069INFLAMMATORY PROCESSES ARE ASSOCIATED WITH INSULIN RESISTANCEAMONGST UK INDIAN ASIANS, AND NOT ACCOUNTED FOR BY OBESITYSehmi, J; Chambers, J; Kooner, JImperial College070AUDIT OF CARDIAC RESYNCHRONISATION THERAPYSmithson, S; Tynan, M; Neville Smith, K; McComb, JFreeman Hospital071ACQUIRED LONG QT SYNDROME: DETERMINANTS AND PROGNOSTICIMPLICATIONS IN A POPULATION-BASED PROSPECTIVE STUDY OF OLDER MENSohaib, S1; Papacosta, O1; Morris, R1; Macfarlane, P2; Whincup, P31. University College London; 2. University of Glasgow; 3. St George’s University of London072ACUTE CORONARY SYNDROME (ACS) AUDIT CYCLE: ASSESSING IMPACT OFIMPLEMENTING ACS SERVICE ON MANAGEMENT AND IN-HOSPITAL LENGTHOF STAY OF PATIENTS ADMITTED WITH NON-ST SEGMENT ELEVATION ACUTECORONARY SYNDROME (NSTEACS)Burrell, C; Syed, F; Sarkar, D; Haywood, G; Cox, I; Motwani, JDerriford Hospital073IS PRE-PROCEDURAL ROTATIONAL ANGIOGRAPHY SUPERIOR TO CONVENTIONAL,SINGLE PLANE ANGIOGRAPHY FOR PLANNING PCI?Taylor, J1; Heppenstall, J2; Bowles, J2; Gunn, J11. University of Sheffield; 2. Northern General Hospital074SAFETY OF EARLY AEROMEDICAL REPATRIATION FOLLOWING ACUTECORONARY SYNDROMEThomas, M1; Hinds, R2; Walker, C2; Morgan, F2; Hildick-Smith, D11. Royal Sussex County Hospital; 2. Healix International Ltd075DOES MINAP (MYOCARDIAL INFARCTION NATIONAL AUDIT PROJECT) ACCURATELYRECORD MEDICAL PRACTICE: A COMPARISON OF MINAP DATA & HOSPITALINFORMATION CONCERNING SECONDARY PREVENTION MEDICATIONValerio, C1; Simunovic, M2; Ray, K31. Hammersmith Hospital; 2. Royal Prince Alfred Hospital; 3. Cambridge University076AUDIT OF CARDIAC REHABILITATION ACROSS THE ENGLISH CARDIAC NETWORKSVarghese, A1; Moqsith, A1; Binder, L2; Tipson, R1; Walsh, M3; Flint, E41. Dudley Group of Hospitals; 2. NHS Heart Improvement Programme; 3. British Cardiac Network Director;4. Cardiology Consultant Black Country Cardiac Network077DÎBLOCAGE – OFF SITE PCI IMPROVES ACCESS TO REVASCULARISATIONIN ACUTE CORONARY SYNDROMES. RESULT OF THE STUDY OF ANGIOGRAPHYAND REVASCULARISATION IN SWINDON (STARS) AUDITVenkatachalapathy, S; Cannon, C; Pannu, K; Gopal, R; Tholoor, S; keen, C; Kuram, S;Wretham, C; Hyde, TThe Great Western Hospital078COMPLEMENT C3 IS INCORPORATED INTO FIBRIN CLOTS AND RESULTSIN IMPAIRED FIBRINOLYSISCarter, A; Somani, R; Howes, J; Shore, A; Standeven, K; Grant, PUniversity of Leeds079NOX2 MODULATION OF CELL CYCLE INHIBITORY PROTEIN P21CIP1IN ENDOTHELIAL CELLSFan, L1; Vinoj, G2; Brooks, G3; Li, J21. Addenbrookes Hospital; 2. University of Surrey; 3. University of Reading080LDL CONTROLS IL-8 PRODUCTION IN MONOCYTES VIA TRIBBLES-2Guan, H; Eder, K; Sung, H; Sheridan, P; Ward, J; Morton, A; Angyal, A; Sarmay, G;Duda, E; Turner, M; Dower, S; Francis, S; Crossman, D; Kiss-toth, EUniversity of SheffieldProgramme at a glanceMonday 2 June2829

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme081GLYCEMIC STATUS UNDERLIES THE INCREASED ARTERIAL STIFFNESSAND IMPAIRED ENDOTHELIAL FUNCTION IN SOUTH ASIAN STROKESURVIVORS COMPARED TO EUROPEAN CAUCASIAN COUNTERPARTSIN THE UNITED KINGDOMGunarathne, A1; Patel, J1; Gammon, B1; Potluri, R1; Butt, R1; Panjai, N1;Hughes, E1; Lip, G21. University Department of Medicine; 2. University Department of Medicine, City Hospital082DIETARY-INDUCED OBESITY RESULTS IN METABOLIC AND VASCULAR INSULIN-LIKEGROWTH FACTOR 1 (IGF-1) RESISTANCE VIA DISTURBANCE OF THE IGF-1/INSULINSIGNALLING PATHWAYImrie, H; Viswambharan, H; Rajwani, A; Abbas, A; Kahn, M; Wheatcroft, S; Kearney, MUniversity of Leeds083LOW DOSE IV NITRITE DILATES BOTH PERIPHERAL AND CENTRAL VESSELSIN HYPOXIA ? A POTENTIAL NEW THERAPY FOR ISCHAEMIAIngram, T1; Pinder, A1; Bailey, D2; Fraser, A1; James, P11. Cardiff University; 2. University of Glamorgan084INDICES OF APOPTOSIS IN PATIENTS WITH IMPAIRED GLUCOSE TOLERANCEFOLLOWING ACUTE MYOCARDIAL INFARCTIONJessani, S; Karthikeyan, V; Millane, T; Lip, GCity Hospital085A PORCINE ENDOVASCULAR MODEL OF A CHRONIC TOTAL CORONARYARTERY OCCLUSIONKelly, D1; Morton, A2; Raina, T2; Lupton, H3; Arnold, N2; Gunn, J2; Gershlick, A11. Glenfield General Hospital; 2. University of Sheffield; 3. Brivant Ltd086EVIDENCE FOR A POTENTIAL NEW METHOD OF THERAPEUTIC ANGIOGENESIS –INCREASED ENDOTHELIAL CELL MOBILITY AND TUBULE FORMATION IN CELLCULTURE FOLLOWING STABILIZATION OF HYPOXIA-INDUCIBLE FACTORKelly, D1; Mecinovic, J2; Schofield, C2; Gunn, J3; Gershlick, A11. Glenfield Hospital; 2. University of Oxford; 3. Northern General Hospital087IN-VIVO OBSERVATIONS ON ANGIOGENESIS: DOSE-DEPENDENT EFFECTSOF THE PROLYL-4-HYDROXYLASE INHIBITOR, DI-METHYL OXALYL-GLYCINE,ON ARTERIAL DEVELOPMENT IN EMBRYONIC ZEBRAFISHKelly, D1; Mecinovic, J2; Schofield, C2; Gunn, J3; Gershlick, A1; Chico, T41. Glenfield Hospital; 2. University of Oxford; 3. Northern General Hospital; 4. University of Sheffield088ATORVASTATIN ACTIVATES A NOVEL NBS-1 DEPENDENT MECHANISMOF ACCELERATING DNA REPAIR IN ATHEROSCLEROSISMahmoudi, M; Gorenne, I; Mercer, J; Figg, N; Bennett, MAddenbrooke’s Hospital089L-ARGININE SUPPLEMENTATION IN HYPERCHOLESTEROLEMIC PATIENTS WITHTHE ASP298 ENOS VARIANTNair, R1; Dart, A2; Chin-Dusting, J3; Huynh, N3; Huynh, N31. Hull Royal Infirmary; 2. Alfred Hospital; 3. Baker Heart Research Institute090THE CONTRIBUTION OF ENDOTHELIAL-DERIVED HYPERPOLARIZING FACTORAND NITRIC OXIDE TO BASAL AND STIMULATORY VASODILATOR TONE INMETABOLIC SYNDROMEOzkor, M; Murrow, J; Kavtaradze, N; Sheikh, A; Jorgensen, J; Pohlel, K;Manatunga, A; Quyyumi, AEmory UniversityProgramme at a glanceMonday 2 June3031

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme091IN VIVO APPLICATION OF RAPAMYCIN-ELUTING MICROBEADS INHIBITS VEIN GRAFTDISEASE IN A PORCINE MODELRajathurai, T; Rizvi, S; Newby, A; Murphy, GBristol Heart Institute092ACUTE ELEVATION OF PLASMA FREE FATTY ACIDS REDUCES AORTICDISTENSIBILITYRider, O1; Emmanuel, Y2; Clarke, K2; Neubauer, S11. Oxford Centre for Clinical Magnetic Resonance Research; 2. Department of Physiology,Anatomy and Genetics, University of Oxford093WEIGHT LOSS REVERSES AORTIC DISTENSIBILITY CHANGES IN SUBJECTS WITHSEVERE OBESITY BUT NO IDENTIFIABLE CARDIAC RISK FACTORS. A ONE YEARFOLLOW UP STUDYRider, O; Francis, J; Ali, M; Jackson, C; Robinson, M; Robson, M; Neubauer, SOxford Centre for Clinical Magnetic Resonance Research094LONG-TERM ORAL TETRAHYDROBIOPTERIN SUPPLEMENTATION REDUCESATHEROSCLEROSIS IN APOLIPOPROTEIN E-KO MICESchmidt, T1; Crabtree, M1; Hale, A1; O’Neill, C2; Alp, N11. Department of Cardiovascular Medicine, Oxford University; 2. BioMarin Pharmaceutical Inc.095THE ROLE OF THE FIBRINOGEN ALPHA CHAIN IN CONTROLLING THE RATE OF FXIIIACTIVATION: IMPLICATIONS FOR CORONARY ARTERY THROMBUS FORMATIONSmith, K; Adamson, P; Ariens, R; Philippou, H; Grant, PCardiovascular and Diabetes Research in Leeds, The Leeds Institute of Genetics Health and Therapeutics,University of Leeds097DIFFERENTIAL EXPRESSION OF THE HUMAN CARDIAC TROPONIN I GENEBY NUCLEAR FACTOR 1-A (NF1-A) ISOFORMS GENERATED THROUGHALTERNATIVE SPLICINGBrand, N1; Raman, M1; Felkin, L1; Lara-Pezzi, E1; Risebro, C2; Riley, P2; Barton, P31. Heart Science Centre, Imperial College; 2. Molecular Medicine Unit, Institute of Child Health;3. Imperial College London098INSIGHTS INTO MOLECULAR MECHANISMS OF ATRIAL PROFIBRILLATORYREMODELING IN CONGESTIVE HEART FAILURE USING A PROTEOMICS APPROACHDe Souza, A1; Cardin, S2; Wait, R3; Patel, N1; Shiroshita-Takeshita, A2; Camm, A1; Nattel, S21. St. George’s University of London; 2. Montreal Heart Institute and University of Montreal;3. Imperial College London099MYOCARDIAL WALL MOTION IN ZEBRAFISH EMBRYOS ASSESSED BY VIDEO EDGEDETECTION: INFLUENCE OF NOREPINEPHRINE, MS-222 AND TEMPERATUREDenvir, M; Tucker, C; Mullins, JUniversity of Edinburgh100ROLE OF THE KLF15 TRANSCRIPTION FACTOR IN AN ANTI-HYPERTROPHICPATHWAY INVOLVING GSK3ßHussain, S; Lara-Pezzi, E; Brand, NHeart Science Centre, Imperial College London101IS DEPRESSED MYOCYTE CONTRACTILITY AN EARLY EVENT IN THE NATURALHISTORY OF HEART FAILURE?Idigo, W1; Zhang, Y1; Lygate, C1; Carnicer, R1; Dawson, D2; Casadei, B11. John Radcliffe Hospital, University of Oxford; 2. Edinburgh Royal InfirmaryProgramme at a glanceMonday 2 June096ALDOSTERONE ANTAGONISM FOR POORLY CONTROLLED HYPERTENSIONIN TYPE 2 DIABETES: CONFLICTING EFFECTS ON BLOOD PRESSURE, ENDOTHELIALFUNCTION, GLYCAEMIC CONTROL AND HORMONAL PROFILESSwaminathan, K; Davies, J; George, J; Rajendra, N; Struthers, ANinewells Hospital and Medical School102ACE2 OVEREXPRESSION IN THE MYOCARDIUM OF STROKE PRONESPONTANEOUSLY HYPERTENSIVE RATS LEADS TO FIBROSISMasson, R1; Craig, M1; Nicklin, S1; Gilday, K1; McBride, M1; Gregorevic, P2; Allen, J2;Chamberlain, J2; Graham, D1; Dominiczak, A1; Baker, A11. University of Glasgow; 2. Univeristy of Washington32 33

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme103ABNORMAL ELECTRICAL FUNCTION AND HYPERTROPHY OF THE HEART CAUSEDBY LOSS OF INTEGRIN ALPHA 7Nadif, R1; Emerson, M2; Mayer, U3; Neyses, L1; Cartwright, E11. University of Manchester; 2. Imperial College; 3. University of East Anglia104DIFFERENT SOURCES OF OXIDANT STRESS IN THE EARLY AND LATE STAGEOF ATRIAL FIBRILLATIONReilly, S; Alp, N; Casadei, BUniversity of Oxford, Department of Cardiovascular Medicine, John Radcliffe Hospital105THE DELTA AND EPSILON ISOFORMS OF PROTEIN KINASE C HAVEOPPOSING ACTIONS IN HUMAN ATRIAL MUSCLE DURING SIMULATEDISCHAEMIA-REPERFUSION INJURYSivaraman, V; Hausenloy, D; Yellon, DHatter Cardiovascular Institute, University College London and Royal Free Hospitals Medical School106GSK-3B IS NOT A NECESSARY SIGNALLING INTERMEDIATE IN POSTCONDITIONINGWebb, I; Nishino, Y; Clark, J; Marber, MThe Rayne Institute, St Thomas’ Hospital, King’s College107RAS-ASSOCIATION FACTOR 1 (RASSF1A), A NOVEL REGULATOR OF CARDIACHYPERTROPHYZi, M; Oceandy, D; Prehar, S; Pickard, A; Cartwright, E; Neyses, LUniversity of Manchester108THE ÒCYPSTATÓ GENETIC SUBSTUDY OF THE SECONDARY PREVENTION OF ACUTECORONARY EVENTS: REDUCTION OF CHOLESTEROL TO KEY EUROPEAN TARGETS(SPACE ROCKET) TRIALBailey, KLeeds University109TELOMERE LENGTH IS SHORTER IN HEALTHY OFFSPRING OF SUBJECTS WITHCORONARY ARTERY DISEASE: SUPPORT FOR THE TELOMERE HYPOTHESISBrouilette, S1; Whittaker, A1; Stevens, S1; van der Harst, P2; Goodall, A1; Samani, N11. Department of Cardiovascular Sciences, University of Leicester; 2. Department of Experimental Cardiology,University of Groningen110CIRCULATING NEPRILYSIN AND CARDIOVASCULAR RISK: ASSOCIATIONS WITHINSULIN RESISTANCE AND THE METABOLIC SYNDROMECarter, A; Rice, G; Standeven, K; Scott, D; Turner, A; Hooper, N; Grant, PUniversity of Leeds111DOES GENETIC VARIATION IN FTO ACCOUNT FOR THE INCREASED RISKOF OBESITY AND TYPE-2 DIABETES IN UK INDIAN ASIANS?Chambers, J1; Zhang, W1; Zabaneh, D1; Balding, D1; McCarthy, M2; Scott, J1;Elliott, P1; Kooner, J11. Imperial College London; 2. Oxford University112TRANSCRIPTION FACTOR 7-LIKE 2 (TCF7L2), INSULIN ACTION AND RISK OFTYPE 2 DIABETES AMONGST INDIAN ASIAN AND EUROPEAN WHITE MENChambers, J; Scott, J; Meeran, K; Jain, P; Bloom, S; Kooner, JImperial College London113A PROSPECTIVE COMPARISON OF 2D ECHOCARDIOGRAPHY AND N TERMINALPRO-BNP IN THE PREDICTION OF ADVERSE OUTCOME POST ACUTE MYOCARDIALINFARCTIONKelly, D; Khan, S; Ng, L; Squire, IUniversity Hospitals, Leicester114MMP-3 IS ASSOCIATED WITH HEART FAILURE AND ALL CAUSE MORTALITY POSTACUTE MYOCARDIAL INFARCTIONKelly, D1; Khan, S1; Thompson, M2; Ng, L1; Samani, N1; Squire, I11. University Hospitals, Leicester; 2. St. George’s Hospital Medical SchoolProgramme at a glanceMonday 2 June3435

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme115MID-REGIONAL PRO-ATRIAL NATRIURETIC PEPTIDE PREDICTS RISK OF DEATHIN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION. LEICESTER ACUTEMYOCARDIAL INFARCTION PEPTIDE (LAMP) STUDYKhan, S1; Dhillon, O1; Struck, J2; Morgenthaler, N2; Squire, I1; Bergmann, A2;Davies, J1; Ng, L11. University of Leicester; 2. BRAHMS AG116MONOCYTE GENE EXPRESSION PROFILING IN INDIVIDUALS WITH CONTRASTINGFAMILIAL RISK FOR PREMATURE MYOCARDIAL INFARCTIONKrishnan, U1; Wright, J1; Farrugia, R2; Ellis, P3; Watkins, N2; Ouwehand, W2;Goodall, A1; Samani, N11. Department of Cardiovascular Sciences, University of Leicester; 2. Department of Haematology,University of Cambridge and NBS; 3. Wellcome Trust Sanger Institute117CIRCULATING ENDOTHELIAL PROGENITOR CELLS FROM HEALTHY INDIVIDUALSEXHIBIT DIURNAL VARIATIONThomas, H; Redgrave, R; Cunnington, M; Keavney, B; Arthur, HUniversity of Newcastle118ESTROGENS AND LIPID PROFILE IN YOUNG MEN? ASSOCIATION ANALYSISTomaszewski, M1; Charchar, F2; Maric, C3; Kuzniewicz, R4; Gola, M4; Grzeszczak, W4;Zukowska-Szczechowska, E4; Samani, N11. University of Leicester; 2. Queen Mary’s School of Medicine and Dentistry; 3. Georgetown UniversityMedical Center; 4. Medical University of Silesia119H-FABP IS SUPERIOR TO TROPONIN IN PREDICTING LONG-TERM MORTALITYIN SUSPECTED ACS PATIENTSViswanathan, K1; Morrell, C1; Thistlethwaite, S1; Hassan, T2; Barth, J2; Hall, A11. University of Leeds; 2. Leeds General Infirmary120BNP IS THE BEST SINGLE MARKER FOR LONG-TERM MORTALITY IN ACSViswanathan, K1; Morrell, C1; Thistlethwaite, S1; Hassan, T2; Barth, J2; Hall, A11. University of Leeds; 2. Leeds General Infirmary36121MMP 3 – A PREDICTOR OF VENTRICULAR FUNCTION FOLLOWING ACUTEMYOCARDIAL INFARCTION?Weir, R1; Murphy, A1; Petrie, C1; Clements, S1; Steedman, T1; McMurray, J1;Ng, L2; Squire, I2; Dargie, H11. Western Infirmary; 2. Leicester Royal Infirmary122ARE INDIAN ASIANS GENETICALLY HOMOGENEOUS? IMPLICATIONS FORGENETIC ASSOCIATION STUDIESZhang, W1; Zabaneh, D1; Balding, D1; McCarthy, M2; Elliott, P1; Scott, J1;Kooner, J1; Chambers, J11. Imperial College London; 2. Oxford UniversityExchange Auditorium 18.30-20.00Sponsored symposiumServier Laboratories LtdOn the pulse of CV Risk PreventionChair: Dr Nicholas BoonLife in the fast lane: the need for precision controlTo highlight the link between heart rate and ischaemia and the importance of treatingheart rate to a targetProf Roberto FerrariDiagnose on history, treat for a futureWhat can we do today to prepare for future trends in CV risk management?Prof Kim FoxExchange Hall 18.30-20.00Sponsored symposiumMerck, Sharp & Dohme LtdLipids On Trial – Is UK lipid management placing too much emphasis upon LDLmanagement and not fully considering other lipid parameters implicated in CV risk?A courtroom exchange, with Judge/Chair, Prosecution, Defence Councils andExpert Witnesses.Speakers and RolesJudge/Chair:Sue Lawley, broadcaster and journalistProsecution Counsel:Prof Richard HobbsDefence Counsel:Dr Clive WestonExpert witness for the Prosecution: Dr Elizabeth HughesExpert witness for the Defence: Prof Ian Young37Programme at a glanceMonday 2 June

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme at a glanceTuesday 3 June8.4510.15Exchange Auditorium Exchange Hall Charter 3-5 Charter 1 Charter 2 Exchange 1 Exchange 2 Radisson HotelHRUK WorkshopChallenges andcomplications ininterventionalelectrophysiologyBSCMR WorkshopWhen CardiovascularMagnetic Resonance(CMR) makes the difference:Read with the expertsBANCC Debate:Coronary Care –but not as weknow itModerated Posters in Exhibition Hall(1-13)Teach InBSH/PCCSHypertension andHeart FailureBSCRFree communications(selected abstracts) –BSCR Early CareerInvestigator PrizeModerated Posters in Exhibition Hall(1-13)SCSTAbnormal findingsfrom cardiacinvestigations –Nature or Nurture?(Part One)11.1512.4513.0014.0015.30BSE/SCTSEchocardiography inAcute Aortic syndromesIn Exhibition HallHow to use adjunctivetechnology in the cath labBCS/ESC/BCISGuidelines:Development andDeliveranceTeach InBCISExhibition BreakIn Exhibition HallHow to examinethe heartTeach InBSE/BCCAEchocardiography inAdult CHDExhibition BreakBANCCAbstracts(14-21)BANCCAGM(BANCC Members only)BANCC/BACR/HCPUKWomen’s HeartHealthBSH/NCPC/HCPUKAdvanced HFBSCRElectrophysiologicalconsequences ofmyocardial ischaemiaand remodellingYoung ResearchWorkers’ PrizeBasic ScienceA-CBSCRNovel therapeutic developmentsin gene and cell therapy.Presentation of Clinical Scienceand BSCR prizesTeach InBACRCRT and ExerciseHow to use a clinicalgenetic serviceExhibition BreakExhibition BreakBSH/BGS CSVCognitive dysfunctionin heart failureSCSTAGM(SCST Members only)SCSTAbnormal findingsfrom cardiacinvestigations –Nature or Nurture?(Part Two)Programme at a glanceTuesday 3 June16.30BCS Lecture17.3018.0019.0020.00Sponsored SymposiaDaiichi-Sankyo& Eli LillyPosters in Exhibition(123-265)Annual Dinner – Manchester Town HallSponsored SymposiaAstraZenecaPosters in Exhibition(123-265)Annual Dinner – Manchester Town HallHeart Failure Electrophysiology/pacing Intervention Imaging38 39

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeMain Hall Entrance 07.30-19.00RegistrationExchange Auditorium 08.45-10.15Heart Rhythm UK (HRUK)Workshop: Challenges and complications in interventional electrophysiologyChairs:Dr Edward Rowland and Dr Derek ConnellyCase presenters: Dr Guy HaywoodDr Chris PepperDr John BourkeExchange Hall 08.45-10.15British Society of Cardiovascular Magnetic Resonance (BSCMR)Workshop: When Cardiovascular magnetic resonance (CMR) makes the difference:read with the expertsChairs:Prof Stefan Neubauer and Prof Dudley PennellCase presenters: Dr Sonya Babu-NarayanDr Saul MyersonDr Charles PeeblesDr Francisco LeyvaCharter 3-5 08.45-10.15British Association for Nursing in Cardiovascular Care (BANCC)Coronary Care – but not as we know it?Debate: This house believes that DGH coronary care units are still neededin the era of heart attack centresWelcome and introduction: Mrs Jenny Tagney, PresidentChairs: Ms Jan Proctor-King and Dr Mark de BelderFor: Dr Ian Jones and Dr Clive WestonAgainst: Prof Christie Deaton and Prof Roger BoyleCharter 1 08.45-10.15British Society for Heart Failure (BSH)Primary Care Cardiovascular Society (PCCS)Teach-inHypertension and heart failureChairs: Prof Martin Cowie and Dr Nigel RowellHypertension and heart failure: the epidemiology and assessmentin primary careProf Richard HobbsFrom hypertension to heart failure. A continuum of systolic and diastolicdysfunction? Treatment implicationsProf John SandersonDo changes in intracellular ions explain the link between hypertensionand heart failure?Dr Rosaire GrayWhere hypertension and heart failure meet: addressing both kidney andcardiac functionProf Henry DargieCharter 2 08.45-10.15British Society for Cardiovascular Research (BSCR)Free communications (selected abstracts) – BSCR Early Career Investigator PrizeChairs: Dr Barbara McDermott and Dr Michael CurtisReduction of plaque instability by suppression of VSMC apoptosis withsoluble N-cadherinDr Cressida BeechingCharacterisation of the role of dimethylarginine dimethylaminohydrolasesin murine heart post-myocardial infarctionMiss Agnieszka KozakDeficiency of 11ß-hydroxysteroid dehydrogenase type 1 augments the inflammatoryresponse dureing myocardial infarction healingMiss Sara McSweeneyHypoxia inhibits MMP-2 activation and invasion in human cardiac myofibroblastsMiss Kirsten RichesRole of NADPH oxidase-derived reactive oxygen species in cardiac dysfunctionassociated with doxorubicin chemotherapyDr Youyou ZhaoProgramme at a glanceTuesday 3 June4041

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeRadisson Hotel 08.45-10.15Society for Cardiological Science and Technology (SCST)Abnormal findings from cardiac investigations – Nature or Nurture? – Part OneChair: Dr Brian CampbellInherited heart disease – a family concernDr Paul BrennanQT abnormalities – the long and the short of it?Mr David RichleyExhibition Hall 10.15-11.15Moderated PostersBasic ScienceChairs: Prof Bernard Keavney and Prof Ludwig Neyses001RENIN CAUSES RELAXATION OF RAT RENAL ARTERIESBecker, S; Ferro, AKing’s College London002GENOME-WIDE ASSOCIATION STUDY IDENTIFIES MLXIPL AS A NOVELDETERMINANT OF TRIGYCERIDE LEVELS IN MANChambers, J; Elliott, P; Scott, J; Kooner, JImperial College London003UNRAVELLING THE MOLECULAR PHENOTYPE BEHIND FAMILIAL DILATEDCARDIOMYOPATHIES – THE FIRST REPORTED HUMAN FUNCTIONAL STUDYOF A UNIQUE TROPONIN C MUTATION, GLU159ASPJacques, A1; Dyer, E1; McKenna, W2; Marston, S11. NHLI; 2. The Heart Hospital004DOWN-REGULATION OF TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP)-3DEFINES A SUB-POPULATION OF HIGHLY INVASIVE FOAM-CELL MACROPHAGESJohnson, J; Sala-Newby, G; Newby, AUniversity of Bristol005IDIOPATHIC RESTRICTIVE CARDIOMYOPATHY IN CHILDREN IS CAUSED BYMUTATIONS IN CARDIAC SARCOMERE PROTEIN GENESKaski, J1; Syrris, P2; Burch, M3; Tome-Esteban, M4; Fenton, M3; Christiansen, M5;Andersen, P5; Sebire, N3; Ashworth, M3; Deanfield, J1; McKenna, W4; Elliott, P31. Institute of Child Health; 2. University College London; 3. Great Ormond Street Hospital;4. The Heart Hospital; 5. Statens Serum Institut006HETEROGENEOUS SERCA2A TRANSFECTION REDUCES SPONTANEOUS ANDINDUCIBLE VENTRICULAR ARRHYTHMIAS IN THE RAT MODEL OF HEART FAILURELyon, A; Sepehripour, A; Dubb, S; Macleod, K; Poole-Wilson, P; Peters, N; Harding, SImperial CollegeExhibition Hall 10.15-11.15Moderated PostersClinic ScienceChairs: Prof Michael Frenneaux and Prof Keith Channon007LOWER MORTALITY WITH DRUD-ELUTING STENT IN THE “REAL WORLD”Alahmar, A1; Stables, R1; Andron, M1; Egred, M1; Rahman, A2; Albouaini, K1; Patel, B3;Shaw, M1; Grayson, A1; Perry, R11. Cardiothoracic Centre Liverpool; 2. Leeds General Hospital; 3. Royal Liverpool University Hospital008PATHOPHYSIOLOGY & PREVALENCE OF INSULIN RESISTANCE AMONGNON-DIABETIC CHRONIC HEART FAILURE PATIENTS AND ITS RELATIONTO DISEASE SEVERITYAlzadjali, M; Godfrey, V; Khan, F; Choy, A; Wong, A; Petrie, J; Struthers, A; Lang, CUniversity of DundeeProgramme at a glanceTuesday 3 June4243

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme009PERCUTANEOUS AORTIC VALVE REPLACEMENT IN THE UNITED KINGDOM USINGTHE COREVALVE REVALVING SYSTEMAsgar, A; Delahunty, N; Dalby, M; Kelleher, A; Davies, S; Moat, N; Mullen, MRoyal Brompton and Harefield NHS Trust010CAROTID INTIMA-MEDIA THICKNESS AS A SURROGATE MARKER OFATHEROSCLEROSIS AND CARDIOVASCULAR DISEASE RISK IN HEALTHY UK INDIANASIANS AND EUROPEAN WHITESChahal, N1; Lim, T2; Jain, P3; Chambers, J3; Senior, R1; Kooner, J31. Northwick Park Hospital; 2. Northwick Park Hospital; 3. Imperial College011THE PRESENCE OF LEFT ATRIAL THROMBUS DESPITE ANTICOAGULATIONIN PATIENTS UNDERGOING LEFT ATRIAL ABLATION FOR ATRIAL FIBRILLATIONCANNOT BE PREDICTED BY CLINICAL RISK FACTORSde Bono, J; Bull, S; Paisey, J; Tomlinson, D; Rajappan, K; Bashir, Y; Betts, TJohn Radcliffe Hospital012PERCUTANEOUS AORTIC VALVE REPLACEMENT (PAVR) IN SEVERE AORTICSTENOSIS: FIRST UK EXPERIENCEJilaihawi, H1; Spyt, T1; Chin, D1; Logtens, E1; Laborde, J2; Kovac, J11. Glenfield Hospital; 2. Clinique Pasteur013LONG-TERM SAFETY OF BARE-METAL AND DRUG-ELUTING STENTS FOR ON-VERSUS OFF-LABEL INDICATIONSKukreja, N; Daemen, J; Onuma, Y; van Twisk, P; van Domburg, R; Boersma, E;de Jaegere, P; Serruys, PErasmus MCExchange Auditorium 11.15-12.45British Society of Echocardiology (BSE)Society for Cardiothoracic Surgery in Great Britain and Ireland (SCTS)Echocardiography in Acute Aortic syndromesChairs: Dr Simon Ray and Mr Graham CooperAcute Aortic syndromes: clinical features and imaging modalitiesDr Adrian BanningSurgical strategies in Acute Aortic syndromesProf Robert BonserEchocardiography in Acute Aortic syndromesDr Navroz MasaniExchange Hall 11.15-12.45British Cardiovascular Intervention Society (BCIS)Teach inChairs: Dr Rob Henderson and Dr Andrew BishopContrast nephropathy – can we prevent it?Case presentation: Dr Jonathan ByrneCommentary: Dr Jonathan HillRescue PCI – why do we do it?Case presentation: Dr Justin CarterCommentary: Dr Andrew SuttonBetween a rock and a hard place?Case presentation: Dr Andrew EpsteinCommentary: Dr Sarah ClarkeChronic occlusions – should we bother?Case presentation: Dr Andrew WorrallCommentary: Dr James CottonProgramme at a glanceTuesday 3 June4445

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeCharter 3-5 11.15-12.45British Association for Nursing in Cardiovascular Care (BANCC)Abstract sessionChairs: Dr Felicity Astin and Prof Christie DeatonTelemonitoring in Heart Failure: Accessibility and Acceptability.The Home-HF StudyMs Jill RileyEuroaction: Do couples attending a hospital based multidisciplinary familycardiovascular prevention and rehabilitation programme share the samesmoking habits? Do they change together?Ms Catriona JenningsCardiac Misconceptions in Hospital StaffDr Stephen LeslieNurse-Led Chest Pain Assessment: Does It Add Quality?Mr Alun RoebuckICD Storm from the Patient’s Perspective: Understanding the Lived Experienceof Multiple Shocks from an Implantable Cardioverter DefibrillatorMs Hilary BugdenReported Lifestyle Habits in Coronary Patients and Access to CardiacRehabilitation in the Euroaspire III SurveyMs Catriona JenningsEvaluation of a New Device for the Transmission of Electrocardiogramsby E-MailDr Stephen LeslieTransition Care: Evaluation of the Inpatient Needs of Adults with CongenitalHeart DiseaseDr Sayqa Arif016ICD STORM FROM THE PATIENT’S PERSPECTIVE: UNDERSTANDING THE LIVEDEXPERIENCE OF MULTIPLE SHOCKS FROM AN IMPLANTABLE CARDIOVERTERDEFIBRILLATORBugden, HPapworth Hospital NHS Trust017REPORTED LIFESTYLE HABITS IN CORONARY PATIENTS AND ACCESS TO CARDIACREHABILITATION IN THE EUROASPIRE III SURVEYJennings, C1; Kotseva, K1; De Bacquer, D2; De Backer, G2; Keil, U3; Wood, D11. Imperial College London; 2. University of Ghent; 3. University of Munster018EUROACTION: DO COUPLES ATTENDING A HOSPITAL BASED MULTIDISCIPLINARYFAMILY CARDIOVASCULAR PREVENTION AND REHABILITATION PROGRAMMESHARE THE SAME SMOKING HABITS? DO THEY CHANGE TOGETHER?Jennings, C1; Collier, T2; Mead, A1; Jones, J3; Holden, A1; De Bacquer, D4;De Backer, G4; Wood, D11. Imperial College London; 2. London School of Hygiene and Tropical Medicine;3. Brunel University; 4. University of Ghent019CARDIAC MISCONCEPTIONS IN HOSPITAL STAFFLeslie, S; Maclean, E; Patience, F; Corrigall, HRaigmore HospitalProgramme at a glanceTuesday 3 June014TRANSITION CARE: EVALUATION OF THE INPATIENT NEEDS OF ADULTS WITHCONGENITAL HEART DISEASEArif, S1; Hudsmith, L2; Hawkesford, S2; Bowater, S2; Clift, P2; Thorne, S21. Worcester Royal Hospital; 2. University Hospitals Birmingham015EVALUATION OF A NEW DEVICE FOR THE TRANSMISSION OFELECTROCARDIOGRAMS BY E-MAILLeslie, S1; Potts, S2; Macfarlane, P2; Barclay, J11. Raigmore Hospital; 2. Portree Medical Centre020TELEMONITORING IN HEART FAILURE: ACCESSIBILITY AND ACCEPTABILITY.THE HOME-HF STUDYRiley, J1; Dar, O2; Chapman, C3; Dubrey, S4; Rosen, S5; Gabe, J6; Cowie, M21. Royal Brompton Hospital/Imperial College; 2. Imperial College; 3. West Middlesex University Hospital;4. Hillingdon Hospital NHS Trust; 5. Ealing Hospital NHS Trust; 6. Royal Holloway College, University of London021NURSE-LED CHEST PAIN ASSESSMENT: DOES IT ADD QUALITY?Roebuck, ACity Hospitals Sunderland NHS Foundation Trust/Sunderland University4647

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeCharter 2 11.15-12.45British Society for Cardiovascular Research (BSCR)Electrophysiological consequences of myocardial ischaemia and remodellingChairs: Prof Barbara Casadei and Dr Andrew GraceThe myocardial response to injury: stretching the role of calcium?Prof Dr Gerd HasenfussThe impact of ischaemia and remodelling on the myocardium – alternating contractionand sparking arrhythmiasProf David EisnerCellular and electrophysiological remodelling and ventricular arrhythmogenesisProf Nicholas PetersGenetic basis of malignant ventricular arrhythmiasProf Arthur WildeExchange 1 11.15-12.45British Association for Cardiac Rehabilitation (BACR)Teach-inCRT and exercise: optimising patient benefitChair: Prof Clifford GarrattPre biventricular decision making and implantationDr Sahrkaw MuhyaldeenPost implant optimisationDr Sanjiv PetkarCRT plus exerciseProf Patrick Doherty and Ms Sue ArmstrongPanel questionsExchange 2 11.15-12.45British Society for Heart Failure (BSH)British Geriatrics Society – Cardiovascular SectionCognitive dysfunction in heart failureChairs: Dr Peter Cowburn and Dr John BaxterWhat is the association between heart failure and cognitive dysfunction?Dr Duncan ForsythWhat could be the underlying mechanisms?Dr John StarrWhat is the impact of cognitive dysfunction in heart failure?Dr Jackie TaylorHow do we manage cognitive dysfunction and heart failure?Dr John BaxterRadisson Hotel 11.15-12.45Society for Cardiological Science and Technology (SCST)Annual General MeetingSCST members onlyExhibition Break 12.45-14.00Exhibition Hall 13.00-14.00How to use adjunctive technology in the catheter laboratoryChair: Dr Philip MacCarthyIVUS and FFRDr Saqib ChowdharyRotablation and thrombectomyDr Julian StrangeExhibition Hall 13.00-14.00How to examine the heartChairs: Dr Stuart Pringle, Dr Douglas Elder and Dr Shihab KhogaliInteractive session to be conducted on Harvey simulatorProgramme at a glanceTuesday 3 June4849

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeCharter 3-5 13.00-14.00British Association for Nursing in Cardiovascular Care (BANCC)Annual General MeetingBANCC members onlyCharter 2 13.00-14.00Young Research Workers’ Prize – Basic ScienceChair: Prof Michael MarberJudges: Dr Andrew GraceProf Michael SchneiderDr Lip Bun TanFinalists: Basic ScienceA A KontogeorgisB S MacDonaldC R ToriADYSSYNCHRONOUS ACTIVATION IN HETEROZYGOUS CX43 GERMLINE KNOCKOUTMICE INDUCES STEADY STATE POTASSIUM CURRENT REMODELLING ANDSUSTAINED DYSSYNCHRONYKontogeorgis, A1; Kaba, R1; Li, X2; Wit, A3; Morley, G2; Peters, N1; Gutstein, D21. Imperial College St Mary’s NHS Trust; 2. New York University School of Medicine;3. Columbia University College of Physicians and SurgeonsBMECHANISMS OF CARDIAC PLEIOTROPY IN CITED2 DEFICIENCYMacDonald, S1; Bamforth, S1; Farthing, C1; Braganca, J2; Franklyn, A1; Broadbent, C2;Schneider, J2; Schwartz, R3; Saga, Y4; Bhattacharya, S11. University of Oxford, John Radcliffe Hospital; 2. University of Oxford; 3. Baylor College of Medicine;4. National Institute of GeneticsCDIFFERENCES IN CORONARY ARTERY HAEMODYNAMICS DUE TO CHANGES INFLOW AND VASCULAR GEOMETRY AFTER PERCUTANEOUS CORONARYINTERVENTIONTorii, R1; Wood, N1; Hadjiloizou, N2; Dowsey, A3; Wright, A4; Hughes, A2; Davies, J2;Francis, D2; Mayet, J2; Yang, G3; Thom, S2; Xu, X11. Department of Chemical Engineering, Imperial College London; 2. International Centre for CirculatoryHealth, Imperial College Healthcare NHS Trust; 3. Department of Computing, Imperial College London;4. Department of Radiology, St. Mary’s HospitalExchange 1 13.00-14.00How to use a clinical genetics serviceChair: Prof Hugh WatkinsSudden cardiac death syndromesDr Edward BlairCongenital heart diseaseDr Ruth Newbury-EcobExchange Auditorium14.00-15.30 hoursBritish Cardiovascular Society (BCS)European Society Cardiology (ESC)British Cardiovascular Intervention Society (BCIS)Guidelines: Development and DeliveranceChairs: Dr Nicholas Boon and Prof Kim FoxPCI Guidelines – how we do itProf Sigmund SilberClinical versus cost effectiveness: does NICE affect our role as the patient’s advocate?Dr Mark de BelderPutting guidelines into practice: the US approachDr James DovePutting guidelines into practice: the UK approachProf Roger BoyleExchange Hall 14.00-15.30British Society of Echocardiology (BSE)British Congenital Cardiac Association (BCCA)Teach-inEchocardiography in Adult Congenital Heart DiseaseChairs: Dr Gordon Williams, Dr Paul CliftAnatomy of common cardiac defects; echo-anatomic correlationsDr Andrew CookEcho in ACHD: the segmental approachMs Gill WhartonEcho in common cardiac defectsDr Kate EnglishEcho in complex ACHDDr Paul CliftProgramme at a glanceTuesday 3 June5051

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeCharter 3-5 14.00-15.30British Association for Nursing in Cardiovascular Care (BANCC)British Association for Cardiac Rehabilitation (BACR)Heart Care Partnership UK (HCP UK)Women’s heart healthChair: Dr Jane FlintCR provision inequalities: women and ethnicity (based on the UK NACR)Ms Corinna PetreLearning from India: the Mumbai CR experienceDr Aashish ContractorDelivering gender and culturally sensitive services in primary care – is it possible?Mrs Ann-Marie JohnsonCommissioning a PCT CR service for women: can we afford it?Ms Jane MilliganPanel questionsCharter 1 14.00-15.30British Society for Heart Failure (BSH)National Council for Palliative Care (NCPC)Heart Care Partnership UK (HCP UK)Advanced heart failure: optimum clinical care includes embedded supportive strategiesChairs: Prof Martin Cowie and Dr Michael ConnollySupportive care for advanced heart failure – an overviewDr James BeattieAddressing the burden of heart failure on patients and carersDr Yvonne MillerickAre we there yet? Barriers to integrating supportive and palliative careDr Miriam JohnsonQuality and quantity of life for people with heart failure should not be mutuallyexclusiveDr Suzanna HardmanCharter 2 14.00-15.30British Society for Cardiovascular Research (BSCR)Novel therapeutic developments in gene and cell therapyChairs: Prof Andrew Baker and Dr Chris NewmanAdeno-associated virus-6 SERCA2a as a therapy for heart failureProf Sian HardingHIF1α: a promising therapeutic approach for peripheral and myocardial ischaemiaProf Keith ChannonGene and cell therapy for angiogenesisProf Paolo MadedduClinical trials using autologous stem cells for cardiac repairDr Anthony MathurPresentation of Clinical Science and BSCR prizesRadisson Hotel 14.00-15.30Society for Cardiological Science and Technology (SCST)Abnormal findings from cardiac investigations – Nature or Nurture? – Part TwoChair: Dr Christopher EggettThe athletic heart – variations and problemsProf W Stewart HillisIs running a marathon heart breaking?Prof Keith GeorgeCardiac aspects of Fabry diseaseDr Peter WoolfsonExhibition Break 15.30-16.30Exchange Auditorium 16.30-17.30BCS lectureDeath and Regeneration: Cardiac Muscle Cell Number as a Therapeutic TargetSpeaker: Prof Michael SchneiderIntroduced by: Prof Derek YellonThanked by: Dr Nicholas BoonProgramme at a glanceTuesday 3 June5253

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeExhibition Hall 17.30-19.00Posters123SAFETY OF CONTRAST AGENTS IN STRESS ECHOCARDIOGRAPHY FOR EVALUATINGPATIENTS WITH KNOWN OR SUSPECTED CORONARY ARTERY DISEASEAnantharam, B; Bhatia, V; Chahal, N; Gani, F; Senior, RNorthwick Park Hospital124COMPARISON OF ADENOSINE STRESS CONTRAST ECHOCARDIOGRAPHY WITHCARDIOVASCULAR MAGNETIC RESONANCE IN PATIENTS WITH SUSPECTEDCORONARY ARTERY DISEASEArnold, J1; Karamitsos, T1; Francis, J1; Pegg, T1; Searle, N2; Neubauer, S1;Becher, H3; Selvanayagam, J11. University of Oxford Centre for Clinical Magnetic Resonance Research; 2. Department of Cardiology,John Radcliffe Hospital; 3. University Department of Cardiovascular Medicine, John Radcliffe Hospital1252D SPECKLE TRACKING: CAN IT RELIABLY MEASURE THE INOTROPIC EFFECT OFINCREASING DOSES OF DOBUTAMINE, IN NORMAL LEFT VENTRICULAR SEGMENTS?Bhan, A; Kapetanakis, S; Rana, B; Casella, F; Monaghan, MKing's College Hospital126PERCUTANEOUS AORTIC VALVE REPLACEMENT: IS THERE A DIFFERENCEBETWEEN 2D AND 3D TRANSOESOPHAGEAL ECHOCARDIOGRAPHY WHENASSESSING AORTIC ANNULAR DIAMETER?Bhan, A; Kapetanakis, S; Wilson, K; Pearson, P; Wendler, O; El-Gamel, A; MacCarthy, P;Thomas, M; Monaghan, MKing’s College Hospital127LEFT ATRIAL SIZE DETERMINED BY HAND HELD ECHOCARDIOGRAPHY PREDICTSLONG TERM ADVERSE CARDIAC OUTCOME IN SUBJECTS SCREENED FOR HEARTFAILURE IN THE COMMUNITYDwivedi, G; Galasko, G; Banfield, A; Lim, T; Senior, RNorthwick Park Hospital128MYOCARDIAL VIABILITY ASSESSMENT USING RESTING MYOCARDIAL CONTRASTECHOCARDIOGRAPHY AND NOT BY 99MTECHNETIUM SESTAMIBI SPECTINDEPENDENTLY PREDICTS HARD CARDIAC OUTCOME FOLLOWING ACUTEMYOCARDIAL INFARCTION AND REPERFUSION THERAPYDwivedi, G; Janardhanan, R; Hayat, S; Swinburn, J; Senior, RNorthwick Park Hospital129SUBCLINICAL ABNORMALITIES OF REGIONAL LEFT VENTRICULAR MYOCARDIALDEFORMATION IN EARLY STAGE CHRONIC KIDNEY DISEASE – THE PRECURSOR OFURAEMIC CARDIOMYOPATHY?Edwards, N1; Hirth, A2; Ferro, C3; Townend, J3; Steeds, R31. University of Birmingham; 2. Institute of Clinical Medicine, University of Bergen and Department of HeartDisease, Haukeland University Hospital; 3. University Hospital Birmingham130IMPAIRED DIASTOLIC FUNCTION IN EARLY STAGE CHRONIC KIDNEY DISEASE –THE PRECURSOR TO URAEMIC CARDIOMYOPATHY?Edwards, N1; Ferro, C2; Townend, J2; Steeds, R21. University of Birmingham; 2. University Hospital Birmingham131ISCHAEMIC LEFT VENTRICULAR DYSFUNCTION IS ASSOCIATED WITHINCREASED DYSSYNCHRONYKhan, S1; Heck, P2; Hoole, S2; Dutka, D21. Papworth Hospital; 2. Addenbrooke’s Hospital132ASSESSMENT OF REGIONAL LEFT VENTRICULAR SYSTOLIC FUNCTION USINGSTRAIN AND STRAIN RATE ECHOCARDIOGRAPHY IN ADULT PATIENTS WITHMARFAN SYNDROMEKiotsekoglou, A; Sutherland, G; Kapetanakis, V; Moggridge, J; Nassiri, D;Camm, A; Child, ASt George’s, University of London, LondonProgramme at a glanceTuesday 3 June5455

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme133ASSESSMENT OF CAROTID COMPLIANCE USING A REAL TIME VASCULARULTRASOUND IMAGE ANALYSIS SYSTEM IN ADULT PATIENTS WITH MARFANSYNDROMEKiotsekoglou, A; Moggridge, J; Newey, V; Kapetanakis, V; Kourliouros, A; Kaski, J;Nassiri, D; Camm, A; Sutherland, G; Child, ASt George’s, University of London, London134PRIMARY IMPAIRMENT OF RIGHT VENTRICULAR FUNCTION IN ADULT PATIENTSWITH MARFAN SYNDROMEKiotsekoglou, A1; Kiotsekoglou, A1; Sutherland, G1; Kapetanakis, V1; Moggridge, J1;Mullen, M2; Nassiri, D1; Camm, A1; Child, A11. St George’s, University of London, London; 2. Royal Brompton Hospital, London, UK135LYING AND STANDING CONTRAST ECHOCARDIOGRAPHY FOR THE DIAGNOSISOF HEPATOPULMONARY SYNDROME IN PATIENTS UNDERGOING LIVERTRANSPLANTATIONLenci, I; Alvior, A; Manzia, T; Toti, L; Neuberger, J; Steeds, RUniversity Hospital (Queen Elizabeth)136THE SENSITIVITY OF ECHOCARDIOGRAPHIC PARAMETERS AND BIOIMPEDANCEANALYSIS IN DEFINING RESPONSE TO AN ACUTE VOLUME LOAD IN NORMALVOLUNTEERSNg Kam Chuen, M; Lip, G; MacFadyen, RCity Hospital137RELATIVE RIGHT VENTRICULAR VERSUS LEFT VENTRICULAR FUNCTION INPATIENTS WHO HAVE EITHER HAD OR NOT HAD CABG SURGERY: A CROSSSECTIONAL STUDYYadav, H; Fontana, M; Unsworth, B; Diller, G; Kyriacou, A; Wasan, B; Sharp, A;Mayet, J; Francis, DInternational Centre for Circulatory Health, St Mary’s Hospital & National Heart and Lung Institute,Imperial College, London, UK138CMR DETERMINED INFARCT SIZE IN DIABETIC VS. NON-DIABETICS PATIENTSAFTER FIRST ACUTE MYOCARDIAL INFARCTIONAbidin, N1; Maredia, N1; Bainbridge, G2; Ball, S1; Plein, S1; Greenwood, J11. Academic Unit of Cardiovascular Medicine, University of Leeds; 2. Leeds General Infirmary139CHARACTERISATION AND INITIAL VALIDATION OF AREA-AT-RISK DERIVEDBY T2-MRI IN ACUTE MYOCARDIAL INFARCTIONBerry, C; Kellman, P; Aletras, A; Mancini, C; Chen, M; Hsu, L; Lederman, R; Arai, ANational Institutes of Health140PRECONDITIONING DOES NOT INFLUENCE THE OCCURRENCE OFMICROVASCULAR OBSTRUCTION OR HAEMORRHAGE REVEALED BY MRIIN A PRE-CLINICAL MODEL OF ACUTE REPERFUSED MYOCARDIAL INFARCTIONBerry, C; Kellman, P; Aletras, A; Schenke, W; Hsu, L; Wright, V; Faranesh, A;Lederman, R; Arai, ANational Institutes of Health141REPRODUCIBILITY OF 31-PHOSPHORUS CARDIAC MAGNETIC RESONANCESPECTROSCOPY AT 3TESLAEmmanuel, Y1; Tyler, D2; Cochlin, L2; Holloway, C1; Hudsmith, L3; Clarke, K2;Neubauer, S3; Robson, M31. OCMR and CMRG, University of Oxford; 2. CMRG, University of Oxford; 3. OCMR, University of Oxford142VALUE OF COMBINING TISSUE SYNCHRONISATION MAPPING WITH SCARIMAGING IN PREDICTING MORTALITY AND MORBIDITY AFTER CARDIACRESYNCHRONISATION THERAPYFoley, P1; Leyva, F1; Chalil, S1; Stegemann, B2; Khadjooi, K1; Frenneaux, M3; Smith, R11. Good Hope Hospital, University of Birmingham, Heart of England NHS Foundation Trust;2. Bakken Research Centre, Medtronic Inc; 3. University of BirminghamProgramme at a glanceTuesday 3 June5657

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme143CORONARY ARTERY CALCIFICATION AS A PREDICTOR OF INCREASED CORONARYHEART DISEASE RISK IN UK INDIAN ASIANSJain, P1; Chambers, J1; Elliott, P1; Williams, E2; Kraly, B3; Muscat, S3; Lahiri, A3; Kooner, J11. Imperial College; 2. University College London; 3. Cardiac Imaging and Research Centre,Wellington Hospital148VALIDATION OF ELECTROCARDIOGRAPHIC AND BIOCHEMICAL ESTIMATESOF FIRST ACUTE MYOCARDIAL INFARCT SIZE USING CARDIAC MAGNETICRESONANCE IMAGINGMartin, T1; Murphy, A1; Wagner, G2; Gronning, B1; Flapan, A3; Dargie, H11. Western Infirmary; 2. Duke University MedicalCentre; 3. Royal Infirmary144COMPARISON OF 2D AND MULTI-SLAB 3D MAGNETIC RESONANCE TECHNIQUESFOR MEASURING CAROTID WALL VOLUMESKeenan, N; Grasso, A; Locca, D; Roughton, M; Gatehouse, P; Firmin, D; Pennell, DCMR Unit, Royal Brompton Hospital145INTEGRATED CARDIAC AND VASCULAR ASSESSMENT IN TAKAYASUÕS ARTERITISAND SYSTEMIC LUPUS ERYTHEMATOSUS BY CARDIOVASCULAR MAGNETICRESONANCEKeenan, N1; Mason, J2; Maceira, A1; Roughton, M3; Assomull, R1; O’Hanlon, R1;Andrews, J4; Gatehouse, P1; Firmin, D1; Haskard, D2; Pennell, D11. CMR Unit, Royal Brompton Hospital; 2. Hammersmith Hospital; 3. Royal Brompton Hospital;4. Imperial College146RIGHT VENTRICULAR DILATION MEASURED BY CARDIAC-MRI: AN INDEPENDENTPREDICTOR OF MORTALITY IN PATIENTS WITH MODERATE CHRONIC HEARTFAILUREBourantas, C; Loh, H; Bragadeesh, T; Lukaschuck, E; Garg, S; Tweddel, A; Nikitin, N;Clark, A; Cleland, JDepartment of Cardiology, Academic Unit, The University of Hull, Castle Hill Hospital147MEASUREMENT OF LEFT VENTRICULAR DIMENSIONS WITH CONTRAST ENHANCEDTHREE DIMENSIONAL CINE MAGNETIC RESONANCE IMAGING FACILITATEDBY K-T SENSEMaredia, N1; Kozerke, S2; Abidin, N1; Larghat, A1; Greenwood, J1; Boesiger, P2; Plein, S11. University of Leeds; 2. Institute for Biomedical Engineering, University and ETH Zurich149THE INDEX OF MICROCIRCULATORY RESISTANCE (IMR) BUT NOTCORONARY COLLATERAL SUPPLY, IS ASSOCIATED WITH MICROVASCULAROBSTRUCTION (MVO) REVEALED BY CONTRAST ENHANCED MAGNETICRESONANCE IMAGING (CEMRI)McGeoch, R1; Watkins, S1; Berry, C1; Davie, A2; Byrne, J2; Hillis, W1; Lindsay, M1;Robb, S1; Dargie, H1; Oldroyd, K11. Western Infirmary; 2. Southern General Hospital150A LOW CORONARY CALCIUM SCORE DOES NOT EXCLUDE SIGNIFICANTCORONARY STENOSES IN PATIENTS WITH INTERMEDIATE TO HIGH LIKELIHOODOF CORONARY ARTERY DISEASE: A 64-MDCT AND INVASIVE CORONARYANGIOGRAPHY CORRELATIONNicol, E; Schultz, C; Roughton, M; Padley, S; Rubens, M; Di Mario, C; Davies, SRoyal Brompton Hospital15164-MDCT CORONARY ANGIOGRAPHY COMPARED WITH MYOCARDIAL PERFUSIONSCINTIGRAPHY FOR DIAGNOSIS OF FUNCTIONALLY SIGNIFICANT STENOSISIN PATIENTS WITH LOW TO INTERMEDIATE LIKELIHOOD OF CORONARYARTERY DISEASENicol, E; Stirrup, J; Reyes, E; Roughton, M; Padley, S; Rubens, M; Underwood, SRoyal Brompton Hospital152K-T SENSE-ACCELERATED MYOCARDIAL PERFUSION MR IMAGING AT 3.0 TESLA ?COMPARISON WITH 1.5 TESLASchwitter, J1; Kozerke, S2; Maredia, N3; Suerder, D1; Greenwood, J3; Boesiger, P2; Plein, S31. University Hospital Zurich; 2. Institute for Biomedical Engineering, University and ETH Zurich;3. University of LeedsProgramme at a glanceTuesday 3 June5859

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme153LOW DOSE DOBUTAMINE ADDS INCREMENTAL VALUE TO DELAYED ENHANCEMENTCARDIAC MAGNETIC RESONANCE FOR THE PREDICTION OF ADVERSEREMODELLING FOLLOWING ACUTE MYOCARDIAL INFARCTIONScott, A; Semple, S; Redpath, T; Small, G; Hillis, GAberdeen University158CHANGES IN LEFT VENTRICULAR WALL THICKNESS ARE SEEN EARLYFOLLOWING PERCUTANEOUS AORTIC VALVE REPLACEMENT (PAVR) IN SEVEREAORTIC STENOSISJilaihawi, H1; Chin, D1; Laborde, J2; Logtens, E1; Spyt, T1; Kovac, J11. Glenfield Hospital; 2. Clinique Pasteur154COMBINED LOW DOSE DOBUTAMINE AND DELAYED ENHANCEMENT CMR IS MOREPREDICTIVE OF INFARCT ZONE AND LEFT VENTRICULAR FUNCTIONAL RECOVERYTHAN EITHER ELEMENT ALONEScott, A; Semple, S; Small, G; Redpath, T; Hillis, GAberdeen University159B-TYPE NATRIURETIC PEPTIDE PREDICTS DISEASE SEVERITY IN CHILDREN WITHHYPERTROPHIC CARDIOMYOPATHYKaski, J1; Tome-Esteban, M2; Mead-Regan, S3; Pantazis, A2; Marek, J3; Deanfield, J1;McKenna, W2; Elliott, P21. Institute of Child Health; 2. The Heart Hospital; 3. Great Ormond Street Hospital155CHRONICALLY ISCHAEMIC HIBERNATING MYOCARDIUM REDUCES PREDICTIONOF RECOVERY BY DELAYED ENHANCEMENT CARDIAC MRI IN HEART FAILURESECONDARY TO CORONARY DISEASE WITH NO SYMPTOMS OF ANGINASparrow, P1; Loh, P2; Nikitin, N2; Cleland, J2; Ball, S1; Plein, S11. BHF Cardiac MRI Unit, Leeds General Infirmary; 2. Academic Cardiology Unit, University of Hull156CORONARY ARTERIAL BLOOD SUPPLY OF THE INFERIOR WALL OF THE RIGHTVENTRICLE IN HEARTS WITH EBSTEIN MALFORMATION: RELEVANCE TOÒVERTICALÓ PLICATION OF THE ATRIALISED RIGHT VENTRICLEAdachi, I1; Ho, S1; McCarthy, K1; Uemura, H21. National Heart & Lung Institute, Imperial College London; 2. Royal Brompton Hospital157ROLE OF PLATELET RECEPTOR POLYMORPHISMS AND CULTURE MEDIA ONSTAPHYLOCOCCUS AUREUS-INDUCED PLATELET AGGREGATION: IMPLICATIONSFOR THE PATHOGENESIS OF INFECTIVE ENDOCARDITISDaga, S; Callaghan, J; Shepherd, J; Newby, D; Fitzgerald, JUniversity of Edinburgh160OUTCOME OF SEVERE SYMPTOMATIC AORTIC STENOSIS IN PATIENTS AGED 80AND OVER: BENEFITS OF AORTIC VALVE REPLACEMENTKojodjojo, P1; Gohil, N1; Barker, D1; Youssef, P1; Choong, A2; Koa-Wing, M2; Bayliss, J1;Hackett, D1; Khan, M11. Hemel Hempstead General Hospital; 2. Imperial College London161THE PROGNOSTIC ABILITY OF AORTIC REGURGITATION QUANTIFICATION WITHCARDIOVASCULAR MAGNETIC RESONANCEMyerson, S1; Karamitsos, T1; Francis, J1; Banning, A2; Neubauer, S11. University of Oxford; 2. John Radcliffe Hospital162PHYSIOLOGICAL CHANGES WITH DOBUTAMINE STRESS IN TETRALOGY OF FALLOT:A PROSPECTIVE MRI PILOT STUDYParish, V1; Greil, G1; Bell, A1; Head, C2; Hancock, J2; Beerbaum, P11. King’s College; 2. St Thomas’ HospitalProgramme at a glanceTuesday 3 June6061

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme163SINGLE CENTRE UNIVERSITY HOSPITAL PREGNANCY OUTCOMES IN PATIENTS WITHCARDIAC CONDITIONSRafiq, I; Rekhraj, S; Parthasarathy, H; Freeman, L; Stanley, KNorfolk and Norwich University Hospital169OUTCOME OF DEFIBRILLATOR IMPLANTATION IN PATIENTS REFERRED FORLONG QT SYNDROME GENETIC TESTINGDiab, I1; Moreton, N2; Newman, W2; Metcalfe, K2; Fitzpatrick, A1; Davidson, N3; Garratt, C11. Manchester Heart Centre; 2. Regional Clinical Genetics Unit; 3. Wythenshawe Hospital164PREGNANCY OUTCOME IN WOMEN WITH SYSTEMIC RIGHT VENTRICLES –A UK SINGLE CENTRE EXPERIENCE AT UNIVERSITY COLLEGE HOSPITAL LONDONNHS TRUST. KATE VON KLEMPERER, RUTH BROOKS, JUSTIN O’LEARY,SHAY CULLEN, PATRICK O’BRIEN, FIONA WALKERVon Klemperer, K; Brooks, R; O’Leary, J; Cullen, S; O’Brien, P; Walker, FThe Heart Hospital165A NOVEL LOW TILT WAVEFOM FOR THE INTERNAL DEFIBRILLATIONOF VENTRICULAR FIBRILLATIONBennett, J1; Darragh, K1; Walsh, S2; Allen, J3; Anderson, J4; Adgey, A1; Manoharan, G51. Royal Victoria Hospital, Queen’s University; 2. Royal Victoria Hospital; 3. Queen’s University;4. Northern Ireland Bioengineering Centre, University of Ulster; 5. Royal Victoria Hospital, Queen’s University,Northern Ireland Bioengineering Centre, University of Ulster166UNDER RECOGNITION OF PAROXYSMAL ATRIAL FIBRILLATION IN A HEARTFAILURE COHORTContractor, H1; Caldwell, J2; Petkar, S1; Neyses, L2; Garratt, C2; Mamas, M21. Manchester Heart Centre; 2. Department of Cardiology, Manchester University167MORBIDITY ASSOCIATED WITH DELAYS TO PERMANENT PACINGCunnington, M; Plummer, C; McComb, JFreeman Hospital168DIAGNOSTIC INVESTIGATIONS LEADING TO PERMANENT PACEMAKERIMPLANTATIONCunnington, M; Plummer, C; McComb, JFreeman Hospital170LEFT VENTRICULAR DYSFUNCTION IN PATIENTS REFERRED FOR PACEMAKERS –IMPLICATIONS FOR PACEMAKER SELECTION.Elder, D1; Alhous, H2; Gavin, A3; Broadhurst, P2; Hillis, G2; Hannah, A2; Grubb, N3;El-Hag, O3; Pringle, T1; Currie, P4; Lang, C1; Choy, A11. Ninewells Hospital; 2. Aberdeen Royal Infirmary; 3. Edinburgh Royal Infirmary; 4. Perth Royal Infirmary171ARE REVEAL DEVICES REALLY COST EFFECTIVE?James, M; Gonna, HMusgrove Park Hospital172FIVE YEAR EXPERIENCE OF DEVICE LEAD EXTRACTIONS IN A UNITED KINGDOMTERTIARY CENTREHamid, M1; Arujuna, A1; Khan, S1; Ladwiniec, A1; Patel, N2; Bucknall, C1; Rinaldi, C11. St Thomas’ Hospital; 2. Eastbourne District General Hospital173EXPERIENCE OF CORONARY SINUS LEAD EXTRACTIONS IN A UNITED KINGDOMTERTIARY CENTREHamid, M1; Arujuna, A1; Khan, S1; Ladwiniec, A1; Patel, N2; Bucknall, C1; Rinaldi, C11. St Thomas’ Hospital; 2. Eastbourne General Hospital174CHANGES IN CARDIAC CONDUCTION AFTER PERCUTANEOUS AORTIC VALVEREPLACEMENT (PAVR) IN SEVERE AORTIC STENOSISJilaihawi, H1; Chin, D1; Laborde, J2; Logtens, E1; Spyt, T1; Kovac, J11. Glenfield Hospital; 2. Clinique PasteurProgramme at a glanceTuesday 3 June6263

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme175ELECTIVE DAY-CASE PERMANENT PACEMAKER IMPLANTATION IS SAFE AND COSTEFFECTIVE: EXPERIENCE FROM A LARGE UK TERTIARY CENTREKrishnamoorthy, S; Nadir, A; Mullin, P; Morley-Davies, A; Creamer, J; Osman, FUniversity Hospital of North Staffordshire181PREDICTORS OF APPROPRIATE SHOCKS AND MORTALITY IN RECIPIENTS OFIMPLANTABLE CARDIOVERTER DEFIBRILLATORSVelavan, P1; Bhat, P2; Kaye, G2; Nasir, M2; Clark, A2; Cleland, J21. Cardio Thoracic Centre; 2. University of Hull176THE RELATIONSHIP BETWEEN RIGHT VENTRICULAR PACING AND ATRIALFIBRILLATION BURDEN IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATIONMcIntosh, R; Veasey, R; Hong, P; Silberbauer, J; Lloyd, G; Patel, N; Sulke, NEastbourne General Hospital177A SINGLE DEFIBRILLATON SAFETY MARGIN TEST IS SUFFICIENT IN MOST PATIENTSAT IMPLANTATION OF AN IMPLANTABLE CARDIOVERTER DEFIBRILLATOROsman, F; Jeilan, M; Habib, A; Kundu, S; Tuan, J; Mantravadi, R; Stafford, P;Pathmanathan, R; Ng, GGlenfield Hospital178COST EFFECTIVENESS OF BI-ATRIAL PACING FOR REFRACTORY ATRIALFIBRILLATIONSankaranarayanan, R; James, M; Gonna, H; Burtchaell, S; Holloway, RTaunton and Somerset Hospital179OPTIMISATION OF CRT IMPROVES LV DIASTOLIC FUNCTIONThomas, D; Vintila, V; Fraser, A; Yousef, ZUniversity Hospital of Wales180THE USEFULNESS OF MINIMAL VENTRICULAR PACING AND PREVENTIVEAF ALGORITHMS IN THE TREATMENT OF PAF: THE MINVPACE STUDYVeasey, R; Arya, A; Hong, P; McIntosh, R; Raghaven, S; Silberbauer, J; Lloyd, G;Patel, N; Sulke, AEastbourne General Hospital182IMMEDIATELY DETECTABLE HEART RATE VARIABILITY CHANGES FOLLOWINGABLATION FOR ATRIAL FIBRILLATION MAY BE AN INDICATION OF VAGAL INJURYLim, P1; Stuber, T1; Koa-Wing, M1; Wright, M2; Kojodjojo, P1; Peters, N1; Davies, D2;Francis, D1; Kanagaratnam, P11. St Mary’s Hospital and Imperial College; 2. St Mary’s Hospital183ELECTROGRAM ANALYSIS USING CARDIAC RIPPLE MAPPING: A NOVEL METHODFOR 3D VISUALISATION OF INTRACARDIAC SIGNALSLinton, N; Koa-Wing, M; Kojodjojo, P; Peters, N; Davies, D; Francis, D; Kanagaratnam, PImperial College Healthcare NHS Trust184REPOLARIZATION RESERVE AND PHYSIOLOGICAL RESTITUTION BY SYMPATHETICNERVE STIMULATION IN LONG QT MODELSMantravadi, R1; Salama, G2; Ng, G31. Department of Cardiovascular Sciences, University of Leicester; 2. Department of Cell Biology Physiology,University of Pittsburgh; 3. University Hospitals of Leicester, Glenfield Hospital185MEASUREMENT OF HUMAN VENTRICULAR REPOLARIZATION USING NON-CONTACTMAPPING – VALIDATION USING CONTACT UNIPOLAR ELECTROGRAMSMurday, D; Turner, N; Yue, A; Roberts, P; Morgan, JSouthampton Universtity Hospitals NHS Trust186RELIABLE BEAT-TO-BEAT ASSESSMENT OF MITRAL ISTHMUS CONDUCTION ORBLOCK BASED ON CORONARY SINUS ACTIVATION PATTERN DURING LEFT ATRIALAPPENDAGE PACING? A SIMPLE METHOD TO FACILITATE MITRAL ISTHMUSABLATIONPaisey, J; Tomlinson, D; de Bono, J; Rajappan, K; Betts, T; Bashir, YOxford Radcliffe HospitalsProgramme at a glanceTuesday 3 June6465

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme187COMPARISON OF SINGLE ABLATION CATHETER VS MULTIPOLAR MAPPINGCATHETER FOR ASSESSMENT OF PULMONARY VEIN CONDUCTIONPaisey, J; Tomlinson, D; de bono, J; Rajappan, K; Bashir, Y; Betts, TOxford Radcliffe Hospitals188INTER-ATRIAL SEPTAL THICKNESS AND DIFFICULTY WITH TRANSSEPTALPUNCTURE DURING CATHETER ABLATION OF ATRIAL FIBRILLATIONTomlinson, D; Sabharwal, N; Yousafzei, M; Bashir, Y; Betts, TJohn Radcliffe Hospital189THE EFFICACY OF INTRAOPERATIVE ATRIAL RADIOFREQUENCY ABLATION FORATRIAL FIBRILLATION DURING CONCOMITANT CARDIAC SURGERY? THE SURGICALATRIAL FIBRILLATION SUPPRESSION (SAFS) STUDYVeasey, R1; Segal, O1; Large, J1; Silberbauer, J1; Hong, P1; McIntosh, R1; Reddy, N2;Lewis, M2; Trivedi, U2; Cohen, A2; Hyde, J2; Sulke, A11. Eastbourne General Hospital; 2. Royal Sussex County Hospital190THE EFFICACY OF PULMONARY VEIN ISOLATION FOR ATRIAL FIBRILLATION INPATIENTS WITH IMPLANTED PERMANENT PACEMAKERS: THE PREVIOUSLY PACEDPULMONARY VEIN ISOLATION (P3VI) STUDYVeasey, R1; Silberbauer, J1; Hong, P1; McIntosh, R1; Morgan, J2; Schilling, R3;Paul, V4; Sulke, A11. Eastbourne General Hospital; 2. Wessex Cardiothoracic Centre; 3. St. Bartholomew’s Hospital;4. St. Peter’s Hospital191PREVALENCE AND INCIDENCE OF INTRAVENTRICULAR CONDUCTION DELAY INPATIENTS WITH HEART FAILURE AND AN IMPLANTABLE CARDIAC DEFIBRILLATORAbdellah, A; Cleland, J; Hurren, S; Cullington, D; Clark, A; Rigby, AAcademic Cardiology Department, Castle Hill Hospital, Hull University192REDUCED TWISTING OF THE LEFT VENTRICLE IN PATIENTS WITH SYMPTOMATICNON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (HCM): A STUDY USINGTWO-DIMENSIONAL SPECKLE TRACKING IMAGINGAbozguia, K1; Nallur Shivu, G1; Ahmed, I1; Phan, T1; Maher, A1; Nassimizadeh, M1;Yousef, Z2; McKenna, W3; Watkins, H4; Elliott, P3; Frenneaux, M11. University of Birmingham; 2. University Hospital of Wales; 3. The Heart Hospital; 4. University of Oxford193CARDIOVASCULAR FUNCTION AND CARDIORESPIRATORY FITNESS IN ADULTSWITH GROWTH HORMONE DEFICIENCYBarker, D1; Moisey, R2; Lewis, N2; Goldspink, D3; Orme, S2; Tan, L21. Royal Liverpool University Hospital; 2. Leeds General Infirmary; 3. John Moore’s University194LV REMODELLING AND LOWER EJECTION FRACTION ARE PARADOXICALLYASSOCIATED WITH ENHANCED CARDIAC FUNCTION IN PATIENTS WITH GROWTHHORMONE DEFICIENCYBarker, D1; Moisey, R2; Lewis, N2; Goldspink, D3; Orme, S2; Tan, L21. Royal Liverpool University Hospital; 2. Leeds General Infirmary; 3. John Moore’s University195DIRECT EVIDENCE IN MAN FOR HAPLOINSUFFICIENCY AS THE MECHANISM OFACTION OF MYOSIN-BINDING PROTEIN C MUTATIONS THAT CAUSE HYPERTROPHICCARDIOMYOPATHYCarballo, S1; Copeland, O2; Livesey, K3; Jacques, A2; McKenna, W4; Redwood, C1;Marston, S2; Watkins, H11. Department of Cardiovascular Medicine, University of Oxford; 2. Cardiac Medicine, National Heartand Lung Institute, Imperial College; 3. Molecular Diagnostics Laboratory, Churchill Hospital;4. Centre for Cardiology in the Young, The Heart Hospital, University College196LEFT VENTRICULAR REMODELLING FOLLOWING CARDIAC RESYNCHRONISATIONTHERAPY IN A CONTEMPORARY HEART FAILURE POPULATIONChandrasekaran, B; Sharma, R; Stirrup, J; Dar, O; Wechalekar, K; Clague, J; Underwood,S; Cowie, M; McDonagh, TImperial College, Royal Brompton & Harefield NHS TrustProgramme at a glanceTuesday 3 June6667

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme197THE HOME HEART FAILURE STUDY (HOME-HF): A RANDOMISED CONTROLLEDTRIAL OF HOME TELEMONITORING OF HEART FAILURE PATIENTS AT HIGH RISKOF READMISSION AND DEATHDar, O1; Riley, J2; Chapman, C3; Dubrey, S4; Morris, S5; Rosen, S6; Cowie, M11. National Heart & Lung Institute, Imperial College London, Royal Brompton Hospital; 2. Royal BromptonHospital, National Heart & Lung Institute, Imperial College London; 3. West Middlesex Hospital NHS Trust;4. Hillingdon Hospital NHS Trust; 5. Health Economics Research Group (HERG), Brunel University;6. Ealing Hospital NHS Trust, Imperial College198DOES BLOOD UREA CONCENTRATION PREDICT EARLY MORTALITY IN PATIENTSHOSPITALISED WITH DECOMPENSATED HEART FAILURE (HF), BETTER THANESTIMATED GLOMERULAR FILTRATION RATE (eGFR)?Jackson, C1; Austin, D1; Tsorlalis, I1; Dalzell, J1; Myles, R1; Rodgers, J2; Stewart, N2;Spooner, R3; Petrie, M2; Cobbe, S1; McMurray, J11. University of Glasgow; 2. Glasgow Royal Infirmary; 3. Gartnavel General Hospital199DISSOCIATION BETWEEN AEROBIC EXERCISE CAPACITY AND CARDIAC PUMPINGCAPABILITY: A LONGITUDINAL STUDY IN PREGNANT WOMENLewis, N1; Barker, D1; Barber, S1; Mason, G2; Tan, L11. University of Leeds; 2. Leeds General Infirmary200PEAK CARDIAC POWER, MEASURED NON-INVASIVELY, IS A POWERFUL PREDICTOROF OUTCOME IN CHRONIC HEART FAILURELim, T1; Mancini, D2; Karlin, P2; Haythe, J2; Levy, W3; Lang, C11. Ninewells Hospital; 2. Columbia University; 3. University of Washington201BIOIMPEDANCE ANALYSIS IS MORE SENSITIVE THAN BODY WEIGHT AT DETECTINGASYMPTOMATIC DIURETIC-INDUCED VOLUME CHANGES IN STABLE PATIENTSWITH LEFT VENTRICULAR SYSTOLIC DYSFUNCTIONNg Kam Chuen, M; Lip, G; MacFadyen, RCity Hospital202DETECTION OF ‘OCCULT’ LEFT VENTRICULAR THROMBUS USINGCONTRAST-ENHANCED CMR IN PATIENTS WITH IMPAIRED VENTRICULARFUNCTION UNDERGOING CORONARY ARTERY BYPASS SURGERYPegg, T1; Karamitsos, T1; Arnold, J1; Francis, J1; Taggart, D1; Neubauer, S1;Selvanayagam, J21. University of Oxford; 2. Flinders Medical Centre203LEFT AND RIGHT VENTRICULAR TISSUE VELOCITIES ARE REDUCED INHYPERTROPHIC CARDIOMYOPATHY BUT NOT IN ATHLETE’S HEARTPetersen, S1; Hudsmith, L1; Ali, M1; Francis, J1; Jerosch-Herold, M2; Markl, M3;Young, A4; Robson, M1; Watkins, H1; Neubauer, S11. Department Cardiovascular Medicine, John Radcliffe Hospital; 2. Brigham and Women’s Hospital,Department Radiology, Cardiovascular Imaging Section; 3. University Hospital Freiburg, Department Radiology,Medical Physics; 4. University of Auckland, Department Anatomy204DIAGNOSTIC YIELD IN FIRST DEGREE RELATIVES OF VICTIMS OF SUDDENADULT DEATH SYNDROME FOLLOWING SYSTEMATIC CLINICAL EVALUATIONIN AN EXPERT SETTINGRawlins, J1; Edwards, C1; Papadakis, M1; Gati, S2; Chlebinski, A3; Sharma, S31. King’s College Hospital; 2. Queen Elizabeth Hospital, Greenwich; 3. University Hospital, Lewisham205VENTRICULAR HYPERTROPHIC RESPONSE PRECEDES VENTRICULAR CAVITYDILATATION IN RESPONSE TO INCREASING BODY MASS INDEXRider, O1; Petersen, S1; Francis, J1; Hudsmith, L1; Ali, M1; Robinson, M1;Clarke, K2; Neubauer, S11. Oxford Centre for Clinical Magnetic Resonance Research; 2. Department of Physiology, Anatomy andGenetics, University of Oxford206VENTRICULAR STRUCTURAL CHANGES IN SUBJECTS WITH SEVERE OBESITYIN THE ABSENCE OF CARDIOVASCULAR RISK FACTORS ARE REVERSIBLEWITH SIGNIFICANT WEIGHT LOSS. A ONE YEAR FOLLOW UP STUDYRider, O; Francis, J; Ali, M; Robinson, M; Neubauer, SOxford Centre for Clinical Magnetic Resonance ResearchProgramme at a glanceTuesday 3 June6869

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme207DO CHOLESTEROL LEVELS INFLUENCE LONG-TERM HEART FAILURE OUTCOMEIN POST-INFARCT PATIENTS WITH MODERATE TO SEVERE LEFT VENTRICULARSYSTOLIC DYSFUNCTION?Sankaranarayanan, R1; James, M2; Gonna, H2; Burtchaell, S2; Holloway, R21. Royal Blackburn Hospital; 2. Taunton and Somerset Hospital212PERIPHERAL PULSATILE ARTERIAL PRESSURE IS DETERMINED BY THE CENTRALRESERVOIR, WHICH IS SIMILAR ACROSS DIFFERENT ARTERIAL SITESMalaweera, A; Davies, J; Hadjiloizou, N; Manisty, C; Aguado-Sierra, J; Zambanini, A;Mayet, J; Francis, D; Parker, K; Hughes, AInternational Centre for Circulatory Health, Imperial College208ABNORMAL LEFT VENTRICULAR SYSTOLIC AND DIASTOLIC FUNCTION ONEXERCISE IN PATIENTS WITH HEART FAILURE AND NORMAL EJECTIONFRACTION (HFNEF)Tan, Y1; Wenzelburger, F1; Lee, E2; Heatlie, G2; Mahadavan, G1; Williams, L1;Leyva, F3; Frenneaux, M1; Sanderson, J11. University of Birmingham; 2. University Hospital of North Staffordshire; 3. Good Hope Hospital & Universityof Birmingham209INVESTIGATION OF RELATIONSHIPS BETWEEN CIRCULATING ENDOTHELIALPROGENITOR CELL NUMBERS, CARDIAC ALLOGRAFT VASCULOPATHYAND DONOR HEART AGE IN CARDIAC TRANSPLANT RECIPIENTSThomas, H1; Parry, G2; Dark, J1; Arthur, H1; Keavney, B11. University of Newcastle; 2. Freeman Hospital210ACUTE HAEMODYNAMIC EFFECTS OF CARDIAC RESYNCHRONISATION THERAPYIN HEART FAILURE WITH A NARROW QRS DURATIONWilliams, L1; Ellery, S2; Bleasdale, R3; Patel, K1; Leyva, F4; Paul, V2; Steendijk, P5;Frenneaux, M11. University of Birmingham; 2. St Peters Hospital; 3. Royal Glamorgan Hospital;4. Good Hope Hospital; 5. University of Leiden211METOPROLOL IMPROVES IRREGULARITY OF VENTRICULAR RATE IN PATIENTSWITH PERMANENT ATRIAL FIBRILLATIONBajpai, A; Batchvarov, V; Kiotsekoglou, A; Dougal, K; Grimster, A; Camm, ASt George’s University of London213THE MECHANISM OF CHRONIC COCAINE EXPOSURE ON CARDIAC REACTIVEOXYGEN SPECIES PRODUCTION AND MAPK ACTIVATIONFan, L1; Sawbridge, D2; Bailey, A2; Kitchen, I2; Li, J21. Addenbrookes Hospital; 2. Cardiovascular Research Theme, Faculty of Health and Medical Sciences,University of Surrey214CARDIOVASCULAR RISK AND PERIPHERAL PULSEWAVE MEASUREMENTIN A POPULATION-BASED STUDYHajat, C; Tobin, M; Gracey, J; Smith, T; Burton, P; Samani, NUniversity of Leicester215CIRCULATING ENDOTHELIAL CELLS AND CIRCULATING PROGENITOR CELLS INHYPERTENSION IN PREGNANCY: A BALANCE BETWEEN ENDOTHELIAL DAMAGEAND REPAIR?Karthikeyan, V; Watson, T; Lane, D; Baghdadi, S; Beevers, D; Lip, GUniversity Department of Medicine, City Hospital216PERIPHERAL ENDOTHELIAL FUNCTION AND ENDOTHELIAL PROGENITOR CELLSREMAIN SUPPRESSED FOLLOWING TREATMENT OF ESSENTIAL HYPERTENSIONSaha, M; Cockburn, J; Zbinden, R; Potter, E; Marber, M; Chowienczyk, PSt Thomas’ Hospital217FEASIBILITY STUDY OF A VIRTUAL APPROACH TO CARDIOVASCULAR RISKMANAGEMENTSinger, D1; Edmunds, M2; Cappuccio, F31. Clinical Sciences Research Institute, University of Warwick Medical School; 2. University Hospital,UHCW NHS Trust; 3. Clinical Sciences Research InstituteProgramme at a glanceTuesday 3 June7071

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme218THE IMPACT OF DIABETES ON 2 YEARS MORTALITY FOLLOWING PERCUTANEOUSCORONARY INTERVENTION (PCI) IN CURRENT ERAAndron, M; Perry, R; Alahmar, A; Egred, M; Grayson, A; Shaw, M; Palmer, N; Stables, RCardiothoracic Centre223RENAL IMPAIRMENT IN HEART ATTACK CENTRE PATIENTS: A REAL WORLDEXPERIENCECampbell, N; De Palma, R; Ahuja, K; Salahuddin, N; Rothman, M; Knight, CLondon Chest Hospital219PERCUTANEOUS AORTIC VALVE REPLACEMENT - WHAT IS THE LIKELY DEMAND INTHE ELDERLY? A 1-YEAR AUDIT OF ADMISSIONS TO A BUSY DISTRICT GENERALHOSPITALBaker, J; Wong, K; Jackson, T; Swallow, R; Radvan, JRoyal Bournemouth and Christchurch NHS Trust220LONG-TERM SAFETY OF DRUG ELUTING STENTS IN THE ELDERLYBehan, M1; Winder, G2; Dixon, G2; Hildick-Smith, D1; Holmberg, S2; de Belder, A21. Sussex Cardiac Centre; 2. Sussex Cardiac Centre221RECRUITABLE CORONARY COLLATERAL SUPPLY AND LEFT VENTRICULARSTIFFNESS ARE LINKED IN ACUTE MYOCARDIAL INFARCTION IN SWINEBerry, C; Schenke, W; Aletras, A; Hsu, L; Wright, V; Faranesh, A; Lederman, R; Arai, ANational Institutes of Health222GENDER, BODY MASS AND THE RISK OF PERI-PROCEDURAL BLEEDINGFOLLOWING PERCUTANEOUS CORONARY INTERVENTION; INSIGHTS FORMTHE BRITISH COLUMBIA CARDIAC REGISTRYByrne, J1; Spence, M2; Chase, A3; Mildenberger, R4; Evans, D5; Melikian, N1;Berry, B6; Pi, D7; Klinke, P4; Fretz, E4; Hilton, D41. King’s College Hospital; 2. The Royal Hospitals; 3. Morriston Hospital; 4. Royal Jubilee Hospital;5. Vancouver Island Health Authority; 6. University of British Columbia; 7. St Paul’s Hospital224INTRA AORTIC BALLOON PUMPING INEFFECTIVE AGAINST SYSTEMICINFLAMMATORY ACTIVATION DURING MYOCARDIAL INFARCTION RELATEDCARDIOGENIC SHOCKCarter, J; Prondzinsky, R; Lemm, H; Swyter, M; Wegener, N; Unverzagt, S; Schlitt, A;Buerke, U; Russ, M; Werdan, K; Buerke, MMartin Luther University Hospital225SHORT AND MEDIUM TERM MORTALITY IN PATIENTS UNDERGOING LEFT MAINSTEM PERCUTANEOUS CORONARY INTERVENTIONDalzell, J; Jadhav, S; Robertson, K; Kelly, J; Lindsay, M; Robb, S; Hillis, W; Oldroyd, KDepartment of Cardiology, Western Infirmary226MICROCIRCULATORY-ORIGINATING PRESSURE PREDOMINATELY DETERMINESCORONARY BLOOD FLOW IN HUMANS: EVALUATION USING WAVE INTENSITYANALYSISDavies, J1; Whinnett, Z1; Hadjiloizou, N1; Manisty, C1; Hughes, A1; Parker, K2;Francis, D1; Mayet, J11. International Centre for Circulatory Health, St Mary’s Hospital and Imperial College;2. Physiological Flow Lab, Department of Bioengineering, Imperial College227CORONARY ARTERY DISEASE IN ASYMPTOMATIC RENAL-TRANSPLANTASSESSMENT PATIENTSGalasko, G1; Frankel, A2; Baker, C11. Cardiology Department, Hammersmith Hospital; 2. Renal Department, Hammersmith HospitalProgramme at a glanceTuesday 3 June7273

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme228LONG-TERM FOLLOW UP OF PATIENTS WITH FOUR OR MORE DRUG ELUTINGSTENTS (DES): IMPLICATIONS FOR CONTEMPORARY INTERVENTIONAL PRACTICEGerber, R1; Ielasi, A2; Godino, C2; Latib, A2; Romagnoli, E2; Airoldi, F2; Chieffo, A2;Montorfano, M2; Rogacka, R2; Melzi, G3; Magni, V2; Carlino, M2; Michev, I2; Colombo, A11. EMO Centro Cuore Columbus & San Raffaele Hospital; 2. San Raffaele Hospital;3. EMO Centro Cuore Columbus229LONG TERM FOLLOW UP OF THE SUB-INTIMAL TRACKING AND RE-ENTRY (STAR)TECHNIQUE FOR CHRONIC TOTAL OCCLUSIONS (CTO)Gerber, R1; Carlino, M2; Godino, C2; Latib, A2; Airoldi, F2; Qasim, A1; Romagnoli, E2;Chieffo, A2; Montorfano, M2; Rogacka, R2; Magni, V2; Cosgrave, J3; Melzi, G3;Michev, I2; Colombo, A11. EMO Centro Cuore Columbus & San Raffaele Hospital; 2. San Raffaele Hospital;3. EMO Centro Cuore Columbus230CORONARY ARTERY VASOMOTION MAY BE POSSIBLE IN SEGMENTS PREVIOUSLYTREATED WITH BIOABSORBABLE MAGNESIUM ALLOY CORONARY STENTSGhimire, G1; Spiro, J1; kharbanda, R1; Roughton, M1; Barlis, P1; Mason, M1; Ilsley, C1;Mitchell, A1; Di Mario, C1; Erbel, R2; Waksman, R3; Dalby, M11. Royal Brompton and Harefield NHS Trust; 2. University of Mainz; 3. Washington Hospital Centre231THE IMPORTANCE OF THE MICROVASCULATURE IN DETERMINING THE SHAPEOF THE LEFT AND RIGHT CORONARY ARTERY FLOW VELOCITY WAVEFORMHadjiloiozu, N; Davies, J; Baksi, A; Baruah, R; Malik, I; Foale, R; Parker, K; Hughes, A;Francis, D; Mayet, JSt Mary’s Hospital and Imperial College London232INCREASING INCIDENCE OF CORONARY PERFORATION IN THE DRUG ELUTINGSTENT ERAHendry, C; Eisenberger, M; Mamas, M; El-Omar, M; Fath-Ordoubadi, F; Fraser, DManchester Heart Centre, Manchester Royal Infirmary233EVALUATION OF SAFETY AND EFFICACY OF TRANSRADIAL PRIMARY ANGIOPLASTYFOR ST SEGMENT ELEVATION MYOCARDIAL INFARCTION Ñ A UK TERTIARYCENTRE’S EXPERIENCEHetherington, S; Morley, R; De Belder, M; Hall, J; Muir, D; Sutton, A; Wright, RThe James Cook University Hospital234ANTI-PLATELET EFFECTS OF ASPIRIN ARE MODIFIED BY CLOPIDOGREL:ASSESSMENT OF A CLINICALLY RELEVANT INTERACTION USING SHORTTHROMBELASTOGRAPHYHobson, A1; Qureshi, Z2; Banks, P1; Curzen, N11. Wessex Cardiac Unit, Southampton University Hospital; 2. Southampton University Medical School235REDUCTION IN POST-PROCEDURAL STAY IN PERCUTANEOUS RELATIVE TO OPENAVR IN SEVERE AORTIC STENOSIS IN OCTOGENARIANSJilaihawi, H1; Spyt, T1; Laborde, J2; Logtens, E1; Chin, D1; Kovac, J11. Glenfield Hospital; 2. Clinique Pasteur236RESCUE PCI ? HOW DO THE OUTCOMES FROM ÔREAL-WORLDÕ PATIENTSCOMPARE TO THE PUBLISHED TRIALS ?Kelly, D; Fairbrother, K; Chitkara, K; Gershlick, AGlenfield Hospital237MULTI-VESSEL PERCUTANEOUS CORONARY INTERVENTION VERSUSCORONARY ARTERY BYPASS SURGERY: A NEW META-ANALYSIS INCORPORATINGDRUG-ELUTING STENT TRIAL DATAKelly, D1; Siddiqi, N1; Holt, M2; Gershlick, A11. Glenfield Hospital; 2. University of Leicester238FACTORS PREDICTING FAILURE OF PERCUTANEOUS CHRONIC TOTAL OCCLUSIONREVASCULARISATION IN THE MODERN ERA: AN ANALYSIS OF 501 CONSECUTIVEREVASCULARISATION ATTEMPTSKhand, A; Lefevre, T; Garot, P; Chettibi, M; Vaquerizo, B; Routledge, H; Louvard, YInstitut Cardiovasculaire Paris SudProgramme at a glanceTuesday 3 June7475

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme239FOUR-YEAR CLINICAL FOLLOW-UP OF THE RAPAMYCIN-ELUTING STENTEVALUATED AT ROTTERDAM CARDIOLOGY HOSPITAL (RESEARCH) REGISTRYKukreja, N; Daemen, J; van Twisk, P; Onuma, Y; de Jaegere, P; van Domburg, R; Serruys, PErasmus MC240LONG-TERM CLINICAL FOLLOW-UP OF 6129 CONSECUTIVE ALL-COMEERSTREATED WITH BARE METAL, SIROLIMU- OR PACLITAXEL-ELUTING STENTSKukreja, N; Daemen, J; van Twisk, P; Onuma, Y; van Domburg, R; Boersma, E; de Jaegere,P; Serruys, PErasmus MC241BIODEGRADABLE-POLYMER-BASED, SIROLIMUS-ELUTING SUPRALIMUS¨ STENT: 6-MONTH ANGIOGRAPHIC AND 30 MONTH CLINICAL FOLLOW-UP RESULTS FROM THESERIES 1 PROSPECTIVE STUDYKukreja, N1; Dani, S2; Parikh, P2; Joshi, H2; Prajapati, J2; Jain, S2; Thanvi, S2;Shah, B3; Dutta, J41. Erasmus MC; 2. SAL Hospital & Medical Institute; 3. Sheth Vadilal Sarabhai General Hospital;4. Sahajanand Medical Technologies Pvt. Ltd.242DO WE HAVE THE COURAGE TO DEFER CORONARY INTERVENTION? A REALWORLD ANALYSISLockie, T; Perera, D; O’Kane, P; Hartley, S; Khan, S; Pattinson, S; Redwood, SSt Thomas’ Hospital243IN VITRO ASSESSMENT OF CARDIAC CATHETER THROMBUS FORMATION WITHBIVALIRUDIN, UNFRACTIONATED HEPARIN, AND ENOXAPARINMaegdefessel, L1; Carter, J1; Schubert, S1; Reindl, I1; Busshardt, M1; Hauroeder, B2;Peetz, D3; Schmidt, H1; Russ, M1; Ebelt, H1; Raaz, U1; Werdan, K1; Buerke, M1; Schlitt, A11. Martin Luther University Hospital; 2. Bundeswehrzentralinstitut der Bundeswehr;3. Johannes Gutenberg University76244REAL WORLD BLEEDING COMPLICATIONS DURING RESCUE PCI; THE MANCHESTERHEART CENTRE EXPERIENCEMamas, M1; Zi, M1; Clarke, B2; El-Omar, M2; Fath-Ordoubadi, F2; Khattar, R2;Appleby, C2; Anwar, M2; Neyses, L1; Fraser, D21. Department of Cardiology, Manchester University; 2. Manchester Heart Centre245A COMPARISON OF FRACTIONAL FLOW RESERVE (FFR) AND MIBI SPECT TODETECT ISCHAEMIC TERRITORIES IN PATIENTS WITH MULTO-VESSEL CORONARYARTERY DISEASEMelikian, N1; De Bondt, P2; Cuisset, T2; Wyffels, E2; Bartunek, J2; Heyndrickx, G2;Wijns, W2; De Bruyne, B21. Cardiovascular Division, King’s College School of Medicine London; 2. Cardiovascular Center Aalst246LEFT MAIN STEM PCI: THE FIRST 250 PATIENTS FROM THE SHEFFIELDUNSELECTED, CONSECUTIVE REGISTRYMorton, A1; Siotia, A2; Gunn, J11. University of Sheffield; 2. Northern General Hospital247TREATMENT OF INTERNAL MAMMARY ARTERY GRAFT STENOSIS WITH DRUGELUTING STENTS COMPARED TO BARE METAL STENTSQasim, A; Cosgrave, J; Latib, A; Airoldi, F; Colombo, AEMO Centro Cuore Columbus248NOVEL TREATMENT OF CLOPIDOGREL INTOLERANCERao, U; Talwar, S; Swallow, RRoyal Bournemouth Hospital249EVALUATION OF THE CLINICAL PERFORMANCE OF THE MEDTRONIC ENDEAVORªABT-578 ELUTING CORONARY STENT SYSTEM IN PATIENTS UNDERGOING PRIMARYPCI FOR ACUTE MYOCARDIAL INFARCTION (AMI). THE ENDEAVORª PRIMARY PCISTUDY (E-PPCI)Singh, R; Dorsch, M; Somers, K; Priestley, C; Mackintosh, A; McLenachan, J;Blaxill, J; Wheatcroft, S; Blackman, D; Greenwood, JLeeds General Infirmary77Programme at a glanceTuesday 3 June

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme250MYOCARDIAL INFARCTION AFTER PERCUTANEOUS CORONARY INTERVENTION:A META-ANALYSIS OF TROPONIN ELEVATION APPLYING THE NEW UNIVERSALDEFINITION.Testa, L1; van Gaal, W2; Bhindi, R1; Porto, I3; Banning, A11. John Radcliffe Hospital; 2. Northern Hospital; 3. Catholic University256N-TERMINAL PRO B TYPE NATRIURETIC PEPTIDE COMPLEMENTS THE GRACERISK SCORE IN PREDICTING EARLY AND LATE DEATHS FOLLOWING ACUTECORONARY SYNDROMEKhan, S1; Ng, K2; Narayan, H2; Quinn, P2; Squire, I2; Davies, J2; Ng, L21. Wythenshawe Hospital; 2. University of Leicester251ADVERSE LOCAL REACTIONS TO THE USE OF HYDROPHILIC SHEATHS FOR RADIALARTERY CANULATIONTharmaratnam, D; Webber, S; Owens, PRoyal Cornwall Hospital257ASSOCIATIONS BETWEEN METHODS OF MEASUREMENT OF ASPIRIN RESISTANCEAND THEIR TEMPORAL VARIATIONS IN PATIENTS WITH ISCHAEMIC HEART DISEASEMuir, A1; McMullin, M2; Patterson, C2; McKeown, P21. Royal Victoria Hospital; 2. Queen’s University252FEMALE GENDER IS ASSOCIATED WITH SIGNIFICANTLY ADVERSE OUTCOMEFOLLOWING PERCUTANEOUS CORONARY INTERVENTION? DATA FROM ACONTEMPORARY ÒREAL-WORLDÓ REGISTRYVenugopal, V; Aher, D; Lipkin, D; Coghlan, J; Rakhit, RRoyal Free Hampstead NHS Trust253INVESTIGATING THE EFFECTS OF ASPIRIN ON BLOOD CLOT STRUCTURE USINGA NOVEL CELLULAR IN VITRO SYSTEMAjjan, R; Standeven, K; Khanbhai, M; Phoenix, F; Kearney, M; Grant, PUniversity of Leeds258REPLACEMENT OF THE PRECORDIAL LEADS OF THE 12-LEADELECTROCARDIOGRAM MAY IMPROVE DETECTION OF ST SEGMENTELEVATION MYOCARDIAL INFARCTIONScott, P; McKavanagh, P; McKaig, N; Murphy, J; Bennet, J; Manoharan, G; Adgey, ARoyal Victoria Hospital259DO PATIENTS DIAGNOSED WITH NON-STEMI BY NEW ESC CRITERIA HAVE THESAME LONG TERM OUTCOME AS OTHER MYOCARDIAL INFARCTS?Teoh, M1; Dubrey, S1; Roughton, M2; Grocott-Mason, R11. Hillingdon Hospital; 2. Royal Brompton NHS TrustProgramme at a glanceTuesday 3 June254THE ICONS RISK SCORE: PREDICTORS OF ONE-YEAR MORTALITY IN PATIENTSWITH ACUTE CORONARY SYNDROME WITHOUT PERSISTENT ST-SEGMENTELEVATION, RESULTS FROM THE IMPROVING CARDIOVASCULAR OUTCOMESIN NOVA SCOTIA (ICONS)Egred, M1; Townley, R2; Mitnistki, A1; Chan, B1; Song, X1; Wang, Y1; Brownell, B1;Cox, J1; Love, M11. Queen Elizabeth II Health Sciences Centre, Halifax Infirmary; 2. Kelowna Hospital, British Colombia255THE SECONDARY PREVENTION OF ACUTE CORONARY EVENTS: REDUCTIONOF CHOLESTEROL TO KEY EUROPEAN TARGETS (SPACE ROCKET) TRIALHall, A1; Space Rocket Investigators, T21. Leeds University; 2. NHS7826030-DAY MORTALITY RATES FOR PATIENTS ADMITTED WITH AN ACUTE CORONARYSYNDROME. CUMULATIVE FUNNEL PLOTS FOR TWO CARDIAC CENTRES WITHINTHE NORTH-EAST OF ENGLANDTurley, A1; Das, R1; Roberts, A1; Morley, R1; Jamieson, S2; de Belder, M1; Haq, I21. James Cook University Hospital; 2. Royal Victoria Infirmary261IS THE INCREASED CARDIOVASCULAR MORTALITY IN SOUTH ASIANS A RESULTOF INCREASED INCIDENCE OR CASE FATALITY? FOUR NEW STUDIES ANDA META-ANALYSISZaman, M; Chen, R; Timmis, A; Marmot, M; Hemingway, HUniversity College London79

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme262EUROACTION: CHANGES IN SMOKING, DIET AND PHYSICAL ACTIVITY OVERONE-YEAR IN A FAMILY BASED PREVENTIVE CARDIOLOGY PROGRAMMEIN HOSPITAL AND GENERAL PRACTICEJones, J1; Jennings, C1; Holden, A1; Connolly, S1; Kotseva, K1; Collier, T2;De Backer, G3; Wood, D11. National Heart and Lung Institute, Imperial College; 2. Department of Epidemiology and Population Health,London School of Hygiene and Tropical Medicine; 3. National Heart and Lung Instutute, Imperial College263A COMPARISON OF EMERGENCY NURSES (EN), EMERGENCY NURSEPRACTITIONERS (ENP) AND EMERGENCY CARE PRACTITIONERS (ECP) USE OFHEURISTICS IN THEIR CLINICAL REASONING AND DECISION MAKING ABILITY TO CORRECTLY MANAGE/TRIAGE PATIENTS PRESENTING WITH CHEST PAINCox, H1; Albarran, J1; Hoskins, R1; Moyle, S1; Quinn, T2; Gray, A2; Lockyer, L11. University of the West of England; 2. Coventry University264DO HEART FAILURE SPECIALIST NURSES REALLY MAKE A DIFFERENCE TO HEALTHRELATED QUALITY OF LIFE, ANXIETY AND DEPRESSION LEVELS AND SELF CAREBEHAVIOURS IN THEIR PATIENTS?Pattenden, J; Coulton, S; Spilsbury, K; Lewin, RUniversity of York265PATIENT, CARER AND PUBLIC INVOLVEMENT IN SUPPORTING PATIENTS WITHCHRONIC HEART FAILUREPeardon, L1; Pratt, R2; Yellowlees, D3; Reid, J4; Leslie, S5; Denvir, M41. Chest, Heart and Stroke, Scotland; 2. University of Edinburgh; 3. St John’s Hospital Livingstsone;4. Royal Infirmary of Edinburgh; 5. Raigmore HospitalExchange Hall 18.00-19.30Sponsored symposiumDaiichi-Sankyo & Eli LillyACS-PCI: Antiplatelet therapy – controversy or consensus?Chair: Prof Anthony Gershlik and Dr Mark de BelderIs the current standard of therapy good enough?Unsolved problems in dual antiplatelet therapyDr Marcus FlatherCan and should we individualise patient therapy?From lab to bedside testingDr Robert StoreyWhen is it time to stop?The balance between late stent thrombosis and bleedingDr Mark de Belder2012 – where will we be with ACS-PCI managementProf Christoph BodeCharter 1 18.00-19.30Sponsored symposiumAstraZenecaManaging the Increasing Burden of Cardiovascular RiskChair: Prof Richard HobbsCost of Treating Risk FactorsDr Chris PooleIs Screening For All RealisticDr Sarah JarvisNew Approaches in the Management of Risk FactorsDr Marc EvansProgramme at a glanceTuesday 3 June8081

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme at a glanceWednesday 4 June8.15Exchange Auditorium Exchange Hall Charter 3-5 Charter 1 Charter 28.459.45Young Research Workers’ PrizeClinical ScienceD-FModerated Posters in Exhibition Hall(22-34)Primary PCIOral Communications(266-272)Moderated Posters in Exhibition Hall(22-34)10.45BCIS WorkshopControversial Decision Makingin Percutaneous CoronaryInterventionHRUK/BSCRTranslational research incardiac electrophysiologyBSHNon compactionand HFBCCALate effects ofCHD12.15AGM(BCS Members only)Exhibition Break13.30BCCA/BSE WorkshopImaging modalities in congenitalheart disease:is there a best or are theycomplimentary?Update onNational CardiovascularAuditsBSH/BSECRTBHF FellowsBCS/Renal Association15.00Exhibition BreakExhibition Break16.0017.00Young Research Workers’Prize AwardsFollowed byThomas Lewis LectureHeart Failure Electrophysiology/pacing Intervention ImagingProgramme at a glanceWednesday 4 June8283

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeMain Hall Entrance 07.30-16.00RegistrationCharter 2 08.15-09.45Primary PCI Oral CommunicationsChairs: Dr David Smith and Prof Martin RothmanState of the Art talkPractical Issues in Primary PCIDr David Smith266AGGRESSIVE PHARMACOINVASIVE THERAPY FOR STEMI MAY DELIVERCOMPARABLE OUTCOMES TO PRIMARY PCI IN A UK SETTINGAdlam, D; Ehtisham, J; McKenna, C; Spyrou, N; Swinburn, J; Orr, WRoyal Berkshire Hospital267PRIMARY ANGIOPLASTY FROM THE RADIAL ROUTE IS SAFE AND EFFECTIVEAND DOES NOT SIGNIFICANTLY INCREASE DOOR TO BALLOON TIMEShahzad, A; Worrall, A; Norell, M; Khogali, S; Cusack, M; Banks, M; Cotton, JNew Cross Hospital268INCIDENCE OF TAKO-TSUBO CARDIOMYOPATHY IN PATIENTS UNDERGOINGPRIMARY ANGIOPLASTY FOR ST ELEVATION MYOCARDIAL INFARCTIONShelton, R; Blackman, D; Greenwood, J; Blaxill, J; Wheatcroft, S; Mackintosh, A;Priestley, C; McLenachan, JYorkshire Heart Centre269PRIMARY PERCUTANEOUS INTERVENTION (PPCI) FOR ST SEGMENT ELEVATIONMYOCARDIAL INFARCTION PROGRAMME UNCOVERS PREVIOUSLY UNDIAGONOSEDCORONARY ARTERY DISEASE THAT REQUIRES REVASCULARISATION: IMPORTANCEFOR SERVICE PLANNINGSingh, R1; Billing, S1; Norell, M1; Cusack, M1; Khogali, S1; Banks, M2; Cotton, J11. Wolverhampton Heart and Lung Centre; 2. Russell Hall Hospital NHS Trust270ABORTED MYOCARDIAL INFARCTION IN THE PRIMARY PCI ERATwomey, D; Kunadian, B; Khan, S; Morley, R; Hall, J; Muir, D; Sutton, A;Wright, R; de Belder, MJames Cook University Hospital271VALIDATION OF RISK ADJUSTMENT MODELS FOR MORTALITY FOLLOWINGPRIMARY PERCUTANEOUS INTERVENTION USING A UK-BASED DATA SETTwomey, D; Kunadian, B; Khan, S; Morley, R; Roberts, A; Sutton, A; Wright, R;Hall, J; Muir, D; de Belder, MJames Cook University Hospital272USING STATISTICAL PROCESS CONTROL TO PLOT THE DOOR-TO-BALLOON TIMEFOR DATA FEEDBACK AND ANALYSIS IN PATIENTS PRESENTING WITH ACUTEMYOCARDIAL INFARCTIONTwomey, D; Kunadian, B; Roberts, A; Morley, R; Hall, J; Sutton, A; Wright, R;Muir, D; de Belder, MThe James Cook University HospitalProgramme at a glanceWednesday 4 June8485

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeExchange Auditorium 08.45-09.45Young Research Workers’ Prize – Clinical ScienceChair: Dr James DoveJudges: Prof Hugh WatkinsProf Julian HalcoxProf Mark KearneyFinalists: Clinical ScienceD P BraundE N RajendraF M SeddonDA NOVEL LOCUS – PSRC1/CELSR2 GENE LOCUS ON CHROMOSOME 1P13.3 – THATAFFECTS SERUM CHOLESTEROL AND IS ASSOCIATED WITH INCREASED RISK OFCORONARY ARTERY DISEASEBraund, P1; Erdmann, J2; Tomaszewski, M1; Gs˘tz, A3; Hajat, C4; Linsel-Nitschke, P2;Mangino, M1; Hengstenberg, C5; Stevens, S1; Stark, K5; Ziegler, A3; Pollard, H1;Caulfield, M6; Hall, A7; Burton, P4; Schunkert, H2; Tobin, M4; Samani, N11. Department of Cardiovascular Sciences, University of Leicester; 2. Medizinische Klinik II,UniversitS˘ t zu LŸbeck; 3. Institut fŸr Medizinische Biometrie und Statistik, UniversitS˘ t zu LŸbeck;4. Department of Health Sciences and Genetics, University of Leicester; 5. Klinik und Poliklinik fŸrInnere Medizin II, UniversitS˘ t Regensburg; 6. Clinical Pharmacology and The Genome Centre,Barts and The London; 7. Leeds Institute for Genetics and Therapeutics, University of LeedsEENDOGENOUS XANTHINE OXIDASE CAUSES PROFOUND VASCULAR OXIDATIVESTRESS AND WIDESPREAD ENDOTHELIAL DYSFUNCTION IN CHRONIC STABLEANGINA PATIENTS DESPITE CONTEMPORARY THERAPYRajendra, N; Ireland, S; George, J; Lang, C; Struthers, AUniversity of DundeeFBASAL VASCULAR TONE IN HUMANS IN VIVO IS REGULATED BY NEURONAL NITRICOXIDE SYNTHASE (nNOS)Seddon, M1; Chowienczyk, P1; Melikian, N1; Dworakowski, R1; Casadei, B2; Shah, A11. King’s College School of Medicine; 2. University of Oxford86Exhibition Hall 09.45-10.45Moderated PostersBasic ScienceChairs: Prof Barbara Casadei and Prof Alistair Hall022PMCA4b MODULATES BETA-ADRENERGIC RESPONSE THROUGH REGULATION OFPHOSPHOLAMBAN PHSPHORYLATIONMohamed, T; Oceandy, D; Alatwi, N; Baudoin, F; Cartwright, E; Neyses, LUniversity of Manchester023THE PLASMA MEMBRANE CALCIUM/CALMODULIN DEPENDENT ATPASE 4 (PMCA4)IS A NOVEL MODULATOR OF MYOCARDIAL HYPERTROPHYOceandy, D; Prehar, S; Zi, M; Mohamed, T; Stanley, P; Cartwright, E; Alatwi, N; Neyses, LUniversity of Manchester024ENDOTHELIAL OVEREPXRESSION OF NOX4 ENHANCES VASORELAXATION ANDLOWERS BLOOD PRESSURE IN MICE IN VIVORay, R; Zhang, M; Ouattara, A; Cave, A; Brewer, A; Shah, AKing’s College London025REPEATED REPLICATION AND META-ANALYSIS OF THE ASSOCIATION BETWEENCHROMOSOME 9P21.3 AND CORONARY ARTERY DISEASESamani, N1; Gs˘tz, A2; Braund, P1; McGinnis, R3; Tregouet, D4; Mangino, M1;Linsel-Nitschke, P2; Cambien, F4; Hengstenberg, C5; Stark, K5; Blankenberg, S6;Tiret, L4; Ducimetiere, P7; Keniry, A3; Ghori, M3; Schreiber, S8; El Mokhtari, N8; Hall, A9;Dixon, R1; Goodall, A1; Liptau, H2; Pollard, H1; Schwarz, D2; Hothorn, L10; Wichmann, H11;Ks˘ nig, I2; Fischer, M5; Meisinger, C12; Ouwehand, W13; Deloukas, P3; Thompson, J1;Erdmann, J2; Ziegler, A2; Schunkert, H21. University of Leicester; 2. UniversitS˘ t zu LŸbeck; 3. Wellcome Trust Sanger Institute;4. INSERM, UMR S 525; 5. UniversitS˘ t Regensburg; 6. Johannes Gutenberg University; 7. UnitÎ INSERM 780;8. UK-SH, Campus Kiel; 9. University of Leeds; 10. Leibniz UniversitS˘ t Hannover; 11. Ludwig MaximiliansUniversity; 12. GSF Nationales Forschungszentrum fŸr Umwelt und Gesundheit; 13. University of Cambridge87Programme at a glanceWednesday 4 June

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgramme026INVESTIGATION OF ENDOTHELIAL PROGENITOR CELL RESPONSES FOLLOWINGELECTIVE PERCUTANEOUS CORONARY INTERVENTION.Thomas, H; Arthur, H; Keavney, BUniversity of Newcastle027ISCHAEMIC PRECONDITIONING IS NOT DEPENDENT UPON GSK-3B INHIBITIONWebb, I; Nishino, Y; Clark, J; Marber, MThe Rayne Institute, St Thomas’ Hospital, Kings CollegeExhibition Hall 09.45-10.45Moderated PostersClinical ScienceChairs: Dr David Newby and Dr Iain Simpson028RELATIONSHIPS BETWEEN PROGNOSTIC, SYMPTOMATIC ANDECHOCARDIOGRAPHIC OUTCOMES AFTER CARDIAC RESYNCHRONISATIONTHERAPYFoley, P1; Chalil, S1; Khadjooi, K1; Stegemann, B2; Frenneaux, M3; Smith, R1; Leyva, F11. Good Hope Hospital, University of Birmingham, Heart of England NHS Foundation Trust;2. Bakken Research Centre, Medtronic Inc; 3. University of Birmingham029THE PATHOPHYSIOLOGIC EFFECTS OF LEFT BUNDLE BRANCH BLOCK:IMPLICATIONS FOR MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY VSRADIONUCLIDE PERFUSION IMAGING FOR THE DETECTION OF CORONARY ARTERYDISEASEHayat, S; Dwivedi, G; Jacobsen, A; Lim, T; Kinsey, C; Senior, RNorthwick Park Hospital030LOCAL PROVISION OF PRIMARY PERCUTANEOUS CORONARY INTERVENTION IN ADISTRICT GENERAL HOSPITAL SETTING: EXTENSION TO 24/7 PROVISIONDRAMATICALLY REDUCES THE NEED FOR RESCUE PERCUTANEOUS CORONARYINTERVENTION WITH ACCEPTABLE DOOR-TO-BALLOON TIMESKong, P; Connolly, D; Ahmad, RSandwell General Hospital, Sandwell and West Birmingham Hospitals NHS Trust88031Title: DOES THE ALDOSTERONE : RENIN RATIO (ARR) PREDICT THE EFFICACYOF SPIRONOLACTONE OVER BENDROFLUMETHAZIDE IN HYPERTENSION?THE RENALDO STUDYParthasarathy, H1; Alhashmi, K2; Struthers, A3; Connell, J2; McInnes, G2;Ford, I4; MacDonald, T31. Norfolk and Norwich University Hospital; 2. Division of Cardiovascular Sciences, Western Infirmary;3. Division of Medicine and Therapeutics, Ninewells Hospital and Medical School; 4. Robertson Centre forBiostatistics, University of Glasgow032ACCURATE DETECTION OF CORONARY ARTERY DISEASE BY ECHOCARDIOGRAPHYUSING PERFLUBUTANE POLYMER MICROSPHERES, A NOVEL CONTRAST AGENT:COMPARISON WITH NUCLEAR PERFUSION IMAGING IN TWO PHASE THREEMULTICENTER CLINICAL TRIALSSenior, R1; Zabalgoitia, M2; Monaghan, M3; Main, M4; Zamorano, J5; Tiemann, K6;Agati, L7; Weissman, N8; Klein, A9; Marwick, T10; Ahmad, M11; DeMaria, A12; Becher, H1;Kaul, S13; Udelson, J14; Wackers, F15; Walovitch, R16; Picard, M171. Northwick Park Hospital; 2. University of Texas Health Science Centre; 3. King’s College Hospital;4. Mid America Heart Institute; 5. University Clinic San Carlos; 6. University of Bonn;7. La Sapienza University of Rome; 8. Cardiovascular Research Institute; 9. Cleveland Clinic;10. Princess Alexandria Hospital; 11. University of Texas; 12. University of California-San Diego;13. Oregon Health Sciences University; 14. Tufts New England Medical Center;15. Yale University School of Medicine; 16. Accusphere Inc; 17. Massachusetts General Hospital033ECGS AND REPERFUSION: DO WE KNOW WHAT WE ARE DOING?Trent, R; Raju, H; Jones, J; Christopherson, FWrexham Maelor Hospital034ECHO IDENTIFICATION AND QUANTIFICATION OF INFLAMMATORY MOLECULES INTHE HEARTYeh, J1; Sennoga, C2; McConnell, E1; Eckersley, R2; Tang, M3; Dawson, D4; Boyle, J5;Seddon, J6; Stepney, A7; Haskard, D1; Nihoyannopoulos, P11. National Heart and Lung Institute, Imperial College London, Hammersmith Campus, Du Cane Road;2. Imaging Sciences Department, Imperial College London, Hammersmith Campus, Du Cane Road;3. Department of Bioengineering, Imperial College London, South Kensington Campus;4. Echocardiology, Hammersmith Hospital, Du Cane Road;5. Histopathology Department, Imperial College London, Hammersmith Campus, Du Cane Road;6. Chemistry Department, Imperial College London, South Kensington Campus, Exhibition Road;7. Central Biomedical Services, Imperial College London, Hammersmith Campus, Du Cane Road89Programme at a glanceWednesday 4 June

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeExchange Auditorium 10.45-12.15British Cardiovascular Intervention Society (BCIS)Workshop – Controversial Decision Making in Percutaneous Coronary InterventionChair: Dr Simon RedwoodPanel: Dr Mark de BelderDr Bernard PrendergastDr Nicholas CurzenDr Christopher YoungData Presentation: Dr Robert HendersonCase 1: Revascularisation in stable anginaDr Andrew BishopCase 2: Major non-cardiac surgery post PCI using drug eluting stentsDr Dan BlackmanCase 3: Incomplete vs complete revascularisation in the setting of AMIDr Mark MasonCase 4: Unprotected left main stentingDr Adrian BanningExchange Hall 10.45-12.15British Society for Cardiovascular Research (BSCR)Heart Rhythm UK (HRUK)Translational research in cardiac electrophysiologyChairs: Prof David Eisner and Dr Andrew GraceAtrial electrophysiology – role of tissue preparationsProf Nicholas PetersAV nodal electrophysiology – new insightsProf Mark BoyettVentricular arrhythmias in heart failure – cellular studiesDr Luigi VenetucciVentricular arrhythmias in heart failure – animal modelsDr Rachel Myles90Charter 1 10.45-12.15British Congenital Cardiac Association (BCCA)Late effects of CHDWhat to expect following repair/palliation for common congenital conditionse.g. Fallot, Fontan, Transposition (Atrial and arterial switch) – recognising the problemsDr Graham StuartSurgical aspects of late problems associated with congenital heart diseaseMr William BrawnMedical aspects to manage late problemsDr Lorna SwanPatient non-medical needs (works, social, personal)Dr Paul WillgossCharter 3-5 10.45-12.15British Society for Heart Failure (BSH)Non compaction and heart failureChairs: Dr Suzanna Hardman and Prof Martin CowieOverview: an emerging epidemic? Evidence, facts and mythsDr Perry ElliottNon-compaction: the spectrum of genotype and phenotypes (to include range ofclinical presentations)Dr Jeffrey TowbinHow best to image: what the different modalities contributeMRIDr Sanjay PrasadEchocardiographyDr Alison DuncanTreatment implicationsDr Theresa McDonaghExchange Hall 12.15-13.30British Cardiovascular Society (BCS)Annual General MeetingBCS members only91Programme at a glanceWednesday 4 June

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeExhibition Break 12.15-13.30Exchange Auditorium 13.30-15.00British Congenital Cardiac Association (BCCA)British Society of Echocardiology (BSE)Imaging modalities in congenital heart disease; is there a best or are theycomplimentary?Chairs: Dr John Simpson and Prof Reza RazaviEchocardiography of natural and repaired congenital heart disease(including 3D, TOE, ICE)Dr Joseph VettukattilCMR for CHD: is this the gold standard?Dr Sonya Babu-NarajanCT for CHD: is this the platinum standard?Dr Vivek MuthuranguGuide to selecting most useful modality for specific clinical situationsDr Peter WildeExchange Hall 13.30-15.00British Cardiovascular Society (BCS)Update on National AuditsChairs: Dr Mark de Belder and Dr Stephen HolmbergOverview of Current AuditsProf Roger BoyleNational Infarct Angioplasty Project (NIAP): Progress reportDr Huon GrayMINAP – the research agendaProf Adam TimmisNCEPOD cardiac surgery project: Final reportDr Mark Signy92Charter 3-5 13.30-15.00British Society for Heart Failure (BSH)British Society of Echocardiology (BSE)CRT: unanswered questionsChairs: Dr Kevin Fox and Dr Peter CowburnDebate: Selection of patients for CRT: echocardiographic measures of dyssynchronyhave a rolePro: Prof John SandersonCon: Dr Andrew ClarkWorkshopWhat is non-response?Prof John ClelandTreating non-response-drugs, devices and system of careDr Rakesh SharmaCharter 1 13.30-15.00British Heart Foundation FellowsChairs: Prof Jeremy PearsonLarge scale population studies in coronary heart disease: past present and futureDr Kausik Ray (BHF Fellow)Pharmacogenomics of hypertensionDr Sandosh Padmanabhan (BHF Fellow)Air pollution and atherothrombosisDr Nicholas Mills (BCS/Michael Davies Fellow)Insulin resistance and the endotheliumProf Mark Kearney (BHF Fellow)93Programme at a glanceWednesday 4 June

British Cardiovascular Society Annual Scientific Conference 2-4 JuneProgrammeCharter 2 13.30-15.00British Cardiovascular Society (BCS)Renal AssociationKidneys and hearts: connected by more than just the aortaChairs: Dr Charles Knight and Dr Kevin HarrisWhy is microalbuminuria a risk factor for cardiovascular disease?Dr Simon SatchellVascular changes in children with chronic kidney diseaseDr Lesley ReesNon-invasive vascular studies in renal patientsDr Charlie FerroMyocardial stunning in patients on haemodialysisDr Chris McIntyreExhibition Break 15.00-16.00Exchange Auditorium 16.00-17.00Young Research Workers’ Prize AwardsFollowed by the Thomas Lewis LectureNew insights into cardiovascular disease from Magnetic Resonance studiesProf Stefan NeubauerIntroduced by: Prof Barbara CassadeiThanked by: Dr Stephen HolmbergProgramme at a glanceWednesday 4 June9495

British Cardiovascular Society Annual Scientific Conference 2-4 JuneFirst author indexAbdellah A Prevalence and incidence of intraventricularconduction delay in patients with heart failure and animplantable cardiac defibrillator. 191Abidin N CMR determined infarct size in diabeticvs. non-diabetics patients after first acute myocardialinfarction. 138Abozguia K Reduced twisting of the left ventricle inpatients with symptomatic non-obstructive hypertrophiccardiomyopathy (HCM): a study using two-dimensionalspeckle tracking imaging. 192Adachi I Coronary arterial blood supply of the inferior wallof the right ventricle in hearts with ebstein malformation:relevance to “vertical” plication of the atrialised rightventricle. 156Addison C Implantable cardioverter defibrillators forprimary prevention following a myocardial infarction:a district general hospital perspective. 035Adlam D Aggressive pharmacoinvasive therapy for stemimay deliver comparable outcomes to primary PCI in aUK setting. 266Ainslie M Awareness of contrast nephropathy at royalbrompton hospital and effectiveness of measures usedto detect it. 036Ajjan R Investigating the effects of aspirin on blood clotstructure using a novel cellular in vitro system. 253Alahmar A Lower mortality with drud-eluting stent in the“real world”. 007Alzadjali M Pathophysiology & prevalence of insulinresistance among non-diabetic chronic heart failurepatients and its relation to disease severity. 008Alzadjali M Effect of metformin on mortality andhospitalizations in patients with heart failure andtype 2 diabetes. 037Anantharam B Safety of contrast agents in stressechocardiography for evaluating patients with knownor suspected coronary artery disease.123Andron M The impact of diabetes on 2 years mortalityfollowing percutaneous coronary intervention (PCI) incurrent era. 218Ang D Addition of b-type natriuretic peptide to thethrombolyisis in myocardial infarction (TIMI) riskscore enhances risk stratification in acute coronarysyndrome. 039Ang D Addition of b-type natriuretic peptide to theglobal registry of acute coronary events (GRACE) scoreenhances risk stratification in acute coronarysyndrome. 038Arif S Transition care: evaluation of the inpatient needsof adults with congenital heart disease. 014Arnold J Comparison of adenosine stress contrastechocardiography with cardiovascular magneticresonance in patients with suspected coronaryartery disease. 124Asgar A Percutaneous aortic valve replacementin the united kingdom using the corevalve revalvingsystem. 009Augustine D Bivalirudin in real world pci: does UKexperience in troponin-positive acute coronarysyndromes match up to acuity? 040Bailey K The “cypstat” genetic substudy of thesecondary prevention of acute coronary events:reduction of cholesterol to key european targets(space rocket) trial. 108Bailey K The prevalence of absolute and relativecontraindications to statin therapy following acutecoronary syndrome. 041Bajpai A Metoprolol improves irregularity of ventricular ratein patients with permanent atrial fibrillation. 211Baker J Percutaneous aortic valve replacement – what isthe likely demand in the elderly? A 1-year audit ofadmissions to a busy district general hospital. 219Barclay J Evaluation of a new device for the transmissionof electrocardiograms by e-mail. 015Barker D LV remodelling and lower ejection fraction areparadoxically associated with enhanced cardiac functionin patients with growth hormone deficiency. 194Barker D Cardiovascular function and cardiorespiratoryfitness in adults with growth hormone deficiency. 193Becker S Renin causes relaxation of rat renal arteries. 001Behan M Assessment of PCI practice – results of anetwork-wide peer review audit assessment. 042Behan M Long-term safety of drug eluting stents inthe elderly. 220Bennett J A novel low tilt wavefom for the internaldefibrillation of ventricular fibrillation. 165Bennett J The experience of cardiac channelopathiesat a tertiary referral centre in Northern Ireland. 043Berry C Preconditioning does not influence the occurrenceof microvascular obstruction or haemorrhage revealedby mri in a pre-clinical model of acute reperfusedmyocardial infarction. 140Berry C Recruitable coronary collateral supply and leftventricular stiffness are linked in acute myocardialinfarction in swine. 221Berry C Coronary artery remodeling is associated withlong-term cardiovascular prognosis. 044Berry C Characterisation and initial validation ofarea-at-risk derived by T2-MRI in acute myocardialinfarction. 139Bhan A Percutaneous aortic valve replacement:is there a difference between 2D and 3Dtransoesophageal echocardiography whenassessing aortic annular diameter? 126Bhan A 2D speckle tracking: can it reliably measure theinotropic effect of increasing doses of dobutamine, innormal left ventricular segments? 125Bowater S The effects of clinic style on access ratesto catheter ablation in the midlands. 046Bowater S Re-processing electrophysiologycatheters. 045Brand N Differential expression of the human cardiactroponin I gene by nuclear factor 1-A (NF1-A) isoformsgenerated through alternative splicing. 097Braund P A novel locus – PSRC1/CELSR2 gene locus onchromosome 1P13.3 – that affects serum cholesterol andis associated with increased risk of coronary arterydisease. DBrouilette S Telomere length is shorter in healthy offspringof subjects with coronary artery disease: support for thetelomere hypothesis. 109Bugden H LCD storm from the patient’s perspective:understanding the lived experience of multiple shocksfrom an implantable cardioverter defibrillator. 016Byrne J Gender, body mass and the risk of peri-proceduralbleeding following percutaneous coronary intervention;insights form the british columbia cardiac registry. 222Campbell N Renal impairment in heart attack centrepatients: a real world experience. 223Carballo S Direct evidence in man for haploinsufficiencyas the mechanism of action of myosin-bindingprotein C mutations that cause hypertrophiccardiomyopathy. 195Carter J Intra aortic balloon pumping ineffective againstsystemic inflammatory activation during myocardialinfarction related cardiogenic shock. 224Carter A Complement C3 is incorporated into fibrin clotsand results in impaired fibrinolysis. 078Carter A Circulating neprilysin and cardiovascular risk:associations with insulin resistance and the metabolicsyndrome. 110Chahal N Carotid intima-media thickness as a surrogatemarker of atherosclerosis and cardiovascular disease riskin healthy UK Indian Asians and European Whites. 010Chambers J Does genetic variation in fto account for theincreased risk of obesity and type-2 diabetes in UKIndian Asians? 111Chambers J Transcription factor 7-like 2 (TCF7l2), insulinaction and risk of type 2 diabetes amongst Indian Asianand European White men. 112Chambers J Genome-wide association study identifiesMLXIPL as a novel determinant of trigyceride levelsin man. 002Chandrasekaran B Left ventricular remodelling followingcardiac resynchronisation therapy in a contemporaryheart failure population. 196Chue C Femoral vascular access complications in adultcongenital heart disease patients: audit from a singletertiary centre. 047Contractor H Under recognition of paroxysmal atrialfibrillation in a heart failure cohort. 166Cooke J Palpitations and psychological morbidity. 048Cunnington M Diagnostic investigations leading topermanent pacemaker implantation. 168Cunnington M Morbidity associated with delays topermanent pacing. 167Daga S Role of platelet receptor polymorphisms andculture media on staphylococcus aureus-inducedplatelet aggregation: implications for the pathogenesisof infective endocarditis. 157Dalzell J Short and medium term mortality in patientsundergoing left main stem percutaneous coronaryintervention. 225Dar O The home heart failure study (home-HF):a randomised controlled trial of home telemonitoringof heart failure patients at high risk of readmissionand death. 197Davies J Microcirculatory-originating pressurepredominately determines coronary blood flow inhumans: evaluation using wave intensity analysis. 226Davies J Peripheral pulsatile arterial pressure isdetermined by the central reservoir, which is similaracross different arterial sites. 212de Bono J The presence of left atrial thrombus despiteanticoagulation in patients undergoing left atrial ablationfor atrial fibrillation cannot be predicted by clinicalrisk factors. 011De Souza A Insights into molecular mechanisms of atrialprofibrillatory remodeling in congestive heart failureusing a proteomics approach. 098Denvir M Myocardial wall motion in zebrafish embryosassessed by video edge detection: influence ofnorepinephrine, MS-222 and temperature. 099Diab I Outcome of defibrillator implantation in patientsreferred for long QT syndrome genetic testing. 169Dorman S Clinical acumen and the treadmill in the rapidaccss chest pain clinic – can we do better? Significantmajor adverse cardiac event rate at 1 year follow up inpatients discharged to their GP. 049Dorman S Lipid-lowering with Simvastatin 40mg followingacute coronary syndromes achieves national NSF/GMSaudit standards but not JBS2 targets for secondaryprevention. 050Dwivedi G Left atrial size determined by hand heldechocardiography predicts long term adverse cardiacoutcome in subjects screened for heart failure inthe community. 127Dwivedi G Myocardial viability assessment using restingmyocardial contrast echocardiography and not by99mtechnetium sestamibi spect independently predictshard cardiac outcome following acute myocardialinfarction and reperfusion therapy. 128Edwards N Subclinical abnormalities of regional leftventricular myocardial deformation in early stagechronic kidney disease – the precursor of uraemiccardiomyopathy? 129Edwards N Impaired diastolic function in early stagechronic kidney disease – the precursor to uraemiccardiomyopathy? 130Egred M The icons risk score: predictors of one-yearmortality in patients with acute coronary syndromewithout persistent ST-segment elevation, resultsfrom the improving cardiovascular outcomes innova scotia (icons). 254Elder D Left ventricular dysfunction in patients referredfor pacemakers – implications for pacemakerselection. 170Emmanuel Y Reproducibility of 31-phosphorus cardiacmagnetic resonance spectroscopy at 3TESLA. 141English C High prevalence of abnormal glucosemetabolism in patients presenting for routine coronaryangiography. 051Fan L NOX2 modulation of cell cycle inhibitory proteinP21CIP1 in endothelial cells. 079Fan L The mechanism of chronic cocaine exposureon cardiac reactive oxygen species production andMAPK activation. 213Foley P Value of combining tissue synchronisationmapping with scar imaging in predicting mortality andmorbidity after cardiac resynchronisation therapy. 142Foley P Relationships between prognostic, symptomaticand echocardiographic outcomes after cardiacresynchronisation therapy. 028Galasko G Coronary artery disease in asymptomaticrenal-transplant assessment patients. 227Gerber R Long term follow up of the sub-intimaltracking and re-entry (star) technique for chronictotal occlusions (CTO). 229Gerber R Long-term follow up of patients with fouror more drug eluting stents (DES): implications forcontemporary interventional practice. 228Ghimire G Coronary artery vasomotion may be possiblein segments previously treated with bioabsorbablemagnesium alloy coronary stents. 230Gonna H Are reveal devices really cost effective? 171Guan H LDL controls IL-8 production in monocytesvia tribbles-2. 080Gunarathne A Glycemic status underlies the increasedarterial stiffness and impaired endothelial function insouth asian stroke survivors compared to europeancaucasians counterparts in the United Kingdom. 081Gunn J CABG and PCI for left main stem coronary arterydisease: synergy in a real world registry. 0529697

British Cardiovascular Society Annual Scientific Conference 2-4 JuneFirst author indexHadjiloiozu N The importance of the microvasculature indetermining the shape of the left and right coronaryartery flow velocity waveform. 231Hajat C Cardiovascular risk and peripheral pulsewavemeasurement in a population-based study. 214Hall AThe secondary prevention of acute coronary events:reduction of cholesterol to key european targets(space rocket) trial. 255Hamid M Five year experience of device lead extractionsin a united kingdom tertiary centre. 172Hamid M Experience of coronary sinus lead extractionsin a United Kingdom tertiary centre. 173Hayat S The pathophysiologic effects of left bundlebranch block: implications for myocardial contrastechocardiography vs radionuclide perfusion imagingfor the detection of coronary artery disease. 029Hendry C Increasing incidence of coronary perforation inthe drug eluting stent era. 232Hetherington S Evaluation of safety and efficacy oftransradial primary angioplasty for ST segmentelevation myocardial infarction – a UK tertiarycentre’s experience. 233Hobson A Anti-platelet effects of aspirin are modified byclopidogrel: assessment of a clinically relevantinteraction using short thrombelastography. 234Hudsmith L Audit of contraception advice in women withheart disease: where are we going wrong? 053Hussain S Role of the KLF15 transcription factor in ananti-hypertrophic pathway involving GSK3ß. 100Idigo W Is depressed myocyte contractility an early eventin the natural history of heart failure? 101Imrie H Dietary-induced obesity results in metabolicand vascular insulin-like growth factor 1 (IGF-1)resistance via disturbance of the IGF-1/insulinsignalling pathway. 082Ingram T Low dose IV nitrite dilates both peripheral andcentral vessels in hypoxia – a potential new therapyfor ischaemia. 083Jackson C Does blood urea concentration predict earlymortality in patients hospitalised with decompensatedheart failure (HF), better than estimated glomerularfiltration rate (EGFR)? 198Jacques A Unravelling the molecular phenotype behindfamilial dilated cardiomyopathies – the first reportedhuman functional study of a unique troponin C mutation,GLU159ASP. 003Jain P Coronary artery calcification as a predictor ofincreased coronary heart disease risk in UK IndianAsians. 143Jeilan M Elective cardioversion under conscious sedation:six year experience of more than 2000 procedures. 054Jenkinson E Accuracy of ambulance staff diagnosis ofacute cardiogenic pulmonary oedema: a prospectivediagnostic study of 1,334 patients. 055Jennings C Euroaction: do couples attending a hospitalbased multidisciplinary family cardiovascular preventionand rehabilitation programme share the same smokinghabits? Do they change together? 018Jennings C Reported lifestyle habits in coronarypatients and access to cardiac rehabilitation in theeuroaspire iii survey. 017Jessani S Indices of apoptosis in patients withimpaired glucose tolerance following acute myocardialinfarction. 084Jilaihawi H Changes in left ventricular wall thicknessare seen early following percutaneous aortic valvereplacement (pavr) in severe aortic stenosis. 158Jilaihawi H Changes in cardiac conduction afterpercutaneous aortic valve replacement (PAVR) insevere aortic stenosis. 174Jilaihawi H Reduction in post-procedural stay inpercutaneous relative to open AVR in severe aorticstenosis in octogenarians. 235Jilaihawi H Percutaneous aortic valve replacement (PAVR)in severe aortic stenosis: First UK experience. 012Johnson J Down-regulation of tissue inhibitor ofmetalloproteinases (TIMP)-3 defines a sub-populationof highly invasive foam-cell macrophages. 004Jones J Euroaction: changes in smoking, diet andphysical activity over one-year in a family basedpreventive cardiology programme in hospital andgeneral practice. 262Karthikeyan V Circulating endothelial cells and circulatingprogenitor cells in hypertension in pregnancy: a balancebetween endothelial damage and repair? 215Kaski J B-type natriuretic peptide predicts disease severityin children with hypertrophic cardiomyopathy. 159Kaski J Idiopathic restrictive cardiomyopathy in childrenis caused by mutations in cardiac sarcomere proteingenes. 005Keenan N Comparison of 2d and multi-slab 3d magneticresonance techniques for measuring carotid wallvolumes. 144Keenan N Integrated cardiac and vascular assessment intakayasu’s arteritis and systemic lupus erythematosusby cardiovascular magnetic resonance. 145Kelly D MMP-3 is associated with heart failure and allcause mortality post acute myocardial infarction. 114Kelly D Multi-vessel percutaneous coronary interventionversus coronary artery bypass surgery: a newmeta-analysis incorporating drug-eluting stenttrial data. 237Kelly D In-vivo observations on angiogenesis: dosedependenteffects of the prolyl-4-hydroxylase inhibitor,di-methyl oxalyl-glycine, on arterial development inembryonic zebrafish. 087Kelly D A porcine endovascular model of a chronic totalcoronary artery occlusion. 085Kelly D Evidence for a potential new method oftherapeutic angiogenesis – increased endothelial cellmobility and tubule formation in cell culture followingstabilization of hypoxia-inducible factor. 086Kelly D Rescue PCI – how do the outcomes from‘real-world’ patients compare to the published trials? 236Kelly D A prospective comparison of 2d echocardiographyand N terminal pro-bnp in the prediction of adverseoutcome post acute myocardial infarction. 113Khan S N-terminal pro B type natriuretic peptidecomplements the grace risk score in predictingearly and late deaths following acute coronarysyndrome. 256Khan S Mid-regional pro-atrial natriuretic peptide predictsrisk of death in patients with acute myocardialinfarction. Leicester acute myocardial infarctionpeptide (lamp) study. 115Khan S Ischaemic left ventricular dysfunction is associatedwith increased dyssynchrony. 131Khand A Factors predicting failure of percutaneouschronic total occlusion revascularisation in the modernera: an analysis of 501 consecutive revascularisationattempts. 238Kiotsekoglou A Assessment of regional left ventricularsystolic function using strain and strain rateechocardiography in adult patients with marfansyndrome. 132Kiotsekoglou A Assessment of carotid compliance usinga real time vascular ultrasound image analysis systemin adult patients with marfan syndrome. 133Kiotsekoglou A Primary impairment of right ventricularfunction in adult patients with marfan syndrome. 134Koa-Wing M Implantable cardioverter defibrillator (ICD)implantation in northwest london: an audit of niceguideline adherence. 056Kojodjojo P Outcome of severe symptomatic aorticstenosis in patients aged 80 and over: benefits of aorticvalve replacement. 160Kong P Local provision of primary percutaneous coronaryintervention in a district general hospital setting:extension to 24/7 provision dramatically reduces theneed for rescue percutaneous coronary intervention withacceptable door-to-balloon times. 030Kontogeorgis A Dyssynchronous activation inheterozygous CX43 germline knockout mice inducessteady state potassium current remodelling andsustained dyssynchrony. AKotseva K Clinical reality of coronary preventionin europe: A comparison of euroaspire i, ii and iiisurveys. 058Kotseva K Euroaspire iii: lifestyle and risk factormanagement and use of drug therapies in coronarypatients from 22 countries in europe. 057Krishnamoorthy S Elective day-case permanentpacemaker implantation is safe and cost effective:experience from a large UK tertiary centre. 175Krishnan U Monocyte gene expression profiling inindividuals with contrasting familial risk for prematuremyocardial infarction. 116Kukreja N Long-term clinical follow-up of 6129consecutive all-comeers treated with bare metal,sirolimu- or paclitaxel-eluting stents. 240Kukreja N Long-term safety of bare-metal anddrug-eluting stents for on- versus off-labelindications. 013Kukreja N Biodegradable-polymer-based, sirolimus-elutingsupralimus® stent: 6-month angiographic and30 month clinical follow-up results from the series1 prospective study. 241Kukreja N Four-year clinical follow-up of the rapamycinelutingstent evaluated at rotterdam cardiology hospital(research) registry. 239Kunadian B External validation of established riskadjustment models for procedural complications afterpercutaneous coronary intervention on an independentdata set in a UK setting. 059Lenci I Lying and standing contrast echocardiography forthe diagnosis of hepatopulmonary syndrome in patientsundergoing liver transplantation. 135Lewis N Dissociation between aerobic exercise capacityand cardiac pumping capability: a longitudinal study inpregnant women. 199Lim T Peak cardiac power, measured non-invasively,is a powerful predictor of outcome in chronic heartfailure. 200Lim P Immediately detectable heart rate variabilitychanges following ablation for atrial fibrillation maybe an indication of vagal injury. 182Linton N Electrogram analysis using cardiac ripplemapping: a novel method for 3d visualisation ofintracardiac signals. 183Lockie T Do we have the courage to defer coronaryintervention? A real world analysis. 242Loh H Right ventricular dilation measured by cardiac-MRI:an independent predictor of mortality in patients withmoderate chronic heart failure. 146Lyon A Heterogeneous SERCA2A transfection reducesspontaneous and inducible ventricular arrhythmiasin the rat model of heart failure. 006MacDonald S Mechanisms of cardiac pleiotropy inCITED2 deficiency. BMaegdefessel L In vitro assessment of cardiac catheterthrombus formation with bivalirudin, unfractionatedheparin, and enoxaparin. 243Mahmoudi M Atorvastatin activates a novel NBS-1dependent mechanism of accelerating dna repairin atherosclerosis. 088Mamas M Real world bleeding complications duringrescue PCI; the manchester heart centreexperience. 244Mantravadi R Repolarization reserve and physiologicalrestitution by sympathetic nerve stimulation in longQT models. 184Maredia N Measurement of left ventricular dimensionswith contrast enhanced three dimensional cine magneticresonance imaging facilitated by K-T sense. 147Martin T Validation of electrocardiographic andbiochemical estimates of first acute myocardial infarctsize using cardiac magnetic resonance imaging. 148Masson R ACE2 overexpression in the myocardium ofstroke prone spontaneously hypertensive rats leadsto fibrosis. 102McGeoch R The index of microcirculatory resistance (IMR)but not coronary collateral supply, is associated withmicrovascular obstruction (MVO) revealed by contrastenhanced magnetic resonance imaging (CEMRI). 149McIntosh R The relationship between right ventricularpacing and atrial fibrillation burden in patients withparoxysmal atrial fibrillation. 176Melikian N A comparison of fractional flow reserve (FFR)and mibi spect to detect ischaemic territories in patientswith multo-vessel coronary artery disease. 245Mohamed T PMCA4B modulates beta-adrenergicresponse through regulation of phospholambanphsphorylation. 022Morton A Left main stem PCI: the first 250 patients fromthe sheffield unselected, consecutive registry. 246Moyle S A comparison of emergency nurses (EN),emergency nurse practitioners (ENP) and emergencycare practitioners (ECP) use of heuristics in their clinicalreasoning and decision making ability to correctlymanage/triage patients presenting with chest pain. 263Muir A Associations between methods of measurementof aspirin resistance and their temporal variationsin patients with ischaemic heart disease. 2579899

British Cardiovascular Society Annual Scientific Conference 2-4 JuneFirst author indexMurday D Measurement of human ventricularrepolarization using non-contact mapping – validationusing contact unipolar electrograms. 185Myerson S The prognostic ability of aortic regurgitationquantification with cardiovascular magneticresonance. 161Nadar S Changes in the use of drug eluting stents forpercutaneous coronary intervention. 060Nadif R Abnormal electrical function and hypertrophy ofthe heart caused by loss of integrin alpha 7. 103Nair R L-Arginine supplementation in hypercholesterolemicpatients with the asp298 enos variant. 089Nair B Adverse risk profile and management delays inpatients without a diagnostic exercise test – limitationsof the rapid access chest pain service model. 061Ng Kam Chuen M The sensitivity of echocardiographicparameters and bioimpedance analysis in definingresponse to an acute volume load in normalvolunteers. 136Ng Kam Chuen M Bioimpedance analysis is moresensitive than body weight at detecting asymptomaticdiuretic-induced volume changes in stable patientswith left ventricular systolic dysfunction. 201Nicol E 64-MDCT coronary angiography comparedwith myocardial perfusion scintigraphy for diagnosisof functionally significant stenosis in patients withlow to intermediate likelihood of coronary arterydisease. 151Nicol E A low coronary calcium score does not excludesignificant coronary stenoses in patients withintermediate to high likelihood of coronary arterydisease: a 64-MDCT and invasive coronary angiographycorrelation. 150Oceandy D The plasma membrane calcium/calmodulindependent atpase 4 (PMCA4) is a novel modulator ofmyocardial hypertrophy. 023Osman F A single defibrillaton safety margin test issufficient in most patients at implantation of animplantable cardioverter defibrillator. 177Ozkor M The contribution of endothelial-derivedhyperpolarizing factor and nitric oxide to basaland stimulatory vasodilator tone in metabolicsyndrome. 090Paisey J Reliable beat-to-beat assessment of mitralisthmus conduction or block based on coronarysinus activation pattern during left atrial appendagepacing – a simple method to facilitate mitralisthmus ablation. 186Paisey J Comparison of single ablation cathetervs multipolar mapping catheter for assessment ofpulmonary vein conduction. 187Parish V Physiological changes with dobutamine stressin tetralogy of fallot: a prospective MRI pilot study. 162Parthasarathy H Does the aldosterone: reninration (ARR) predict the efficacy of spironolactoneover bendroflumethazide in hypertension?The renaldo study. 031Patel M Impact of the JBS2 guidelines on the successof reaching target in patients on lipid lowering statintherapy. 062Patience F Cardiac misconceptions in hospitalstaff. 019Pattenden J Do heart failure specialist nurses reallymake a difference to health related quality of life, anxietyand depression levels and self care behaviours intheir patients? 264Peardon L Patient, carer and public involvement insupporting patients with chronic heart failure. 265Pegg T Detection of ‘occult’ left ventricular thrombus usingcontrast-enhanced CMR in patients with impairedventricular function undergoing coronary arterybypass surgery. 202Petersen S Left and right ventricular tissue velocities arereduced in hypertrophic cardiomyopathy but not inathlete’s heart. 203Plein S K-T sense-accelerated myocardial perfusion mrimaging at 3.0 tesla – comparison with 1.5 tesla. 152Qasim A Treatment of internal mammary artery graftstenosis with drug eluting stents compared to baremetal stents. 247Rafiq I Single centre university hospital pregnancyoutcomes in patients with cardiac conditions. 163Rajathurai T In vivo application of rapamycin-elutingmicrobeads inhibits vein graft disease in a porcinemodel. 091Rajendra N Endogenous xanthine oxidase causesprofound vascular oxidative stress and widespreadendothelial dysfunction in chronic stable angina patientsdespite contemporary therapy. ERamachandra R Left ventricular impairment and long-termmortality from acute coronary syndromes: analysis byhaemoglobin concentration. 063Rao G Patients with metabolic syndrome present withnon-ST elevation myocardial infarction at a youngerage and have worse angiographic findings. 064Rao U Novel treatment of clopidogrel intolerance. 248Rawlins J Diagnostic yield in first degree relatives ofvictims of sudden adult death syndrome followingsystematic clinical evaluation in an expert setting. 204Ray R Endothelial overepxression of NOX4 enhancesvasorelaxation and lowers blood pressure in micein vivo. 024Reilly S Different sources of oxidant stress in the earlyand late stage of atrial fibrillation. 104Rider O Ventricular structural changes in subjects withsevere obesity in the absence of cardiovascular riskfactors are reversible with significant weight loss.A one year follow up study. 206Rider O Weight loss reverses aortic distensibility changesin subjects with severe obesity but no identifiable cardiacrisk factors. A one year follow up study. 093Rider O Acute elevation of plasma free fatty acids reducesaortic distensibility. 092Rider O Ventricular hypertrophic response precedesventricular cavity dilatation in response to increasingbody mass index. 205Riley J Telemonitoring in heart failure: accessibility andacceptability. The home-HF study. 020Roebuck A Nurse-led chest pain assessment: does itadd quality? 021Saha M Peripheral endothelial function and endothelialprogenitor cells remain suppressed following treatmentof essential hypertension. 216Salaahshouri P Clinical outcomes in pre-hospitalthrombolysis in a rural setting. 065Samani N Repeated replication and meta-analysis of theassociation between chromosome 9P21.3 and coronaryartery disease. 025Sankaranarayanan R Do cholesterol levels influencelong-term heart failure outcome in post-infarct patientswith moderate to severe left ventricular systolicdysfunction? 207Sankaranarayanan R Cost effectiveness of bi-atrialpacing for refractory atrial fibrillation. 178Sankaranarayanan R Is rate or regularity the moreimportant risk predictor in post-myocardial infarctionatrial fibrillation? 066Schmidt T Long-term oral tetrahydrobiopterinsupplementation reduces atherosclerosis inapolipoprotein E-KO mice. 094Schmitt M Appropriateness assessment of cardiac MRIutilisation and the role of viability imaging in the patientcare algorithm. 067Scott P Replacement of the precordial leads of the 12-leadelectrocardiogram may improve detection of ST segmentelevation myocardial infarction. 258Scott A Combined low dose dobutamine and delayedenhancement cmr is more predictive of infarct zoneand left ventricular functional recovery than eitherelement alone. 154Scott A Low dose dobutamine adds incremental value todelayed enhancement cardiac magnetic resonance forthe prediction of adverse remodelling following acutemyocardial infarction. 153Scott P Declining lipid levels in patients admitted withmyocardial infarction to a regional cardiology centre2000-2006. 068Seddon M Basal vascular tone in humans in vivo isregulated by neuronal nitric oxide synthase (NNOS). FSehmi J Inflammatory processes are associated withinsulin resistance amongst UK Indian Asians, and notaccounted for by obesity. 069Senior R Accurate detection of coronary artery diseaseby echocardiography using perflubutane polymermicrospheres, a novel contrast agent: comparison withnuclear perfusion imaging in two phase three multicenterclinical trials. 032Shahzad A Primary angioplasty from the radial route issafe and effective and does not significantly increasedoor to balloon time. 267Shelton R Incidence of tako-tsubo cardiomyopathy inpatients undergoing primary angioplasty for ST elevationmyocardial infarction. 268Singer D Feasibility study of a virtual approach tocardiovascular risk management. 217Singh R Evaluation of the clinical performance of themedtronic endeavor ABT-578 eluting coronary stentsystem in patients undergoing primary PCI for acutemyocardial infarction (AMI). The Endeavor primary PCIstudy (E-PPCI). 249Singh R Primary percutaneous intervention (PPCI) forST segment elevation myocardial infarction programmeuncovers previously undiagonosed coronary arterydisease that requires revascularisation: importancefor service planning. 269Sivaraman V The delta and epsilon isoforms of proteinkinase C have opposing actions in human atrial muscleduring simulated ischaemia-reperfusion injury. 105Smith K The role of the fibrinogen alpha chain incontrolling the rate of FXIII activation: implications forcoronary artery thrombus formation. 095Smithson S Audit of cardiac resynchronisationtherapy. 070Sohaib S Acquired long QT syndrome: determinants andprognostic implications in a population-basedprospective study of older men. 071Sparrow P Chronically ischaemic hibernating myocardiumreduces prediction of recovery by delayed enhancementcardiac MRI in heart failure secondary to coronarydisease with no symptoms of angina. 155Swaminathan K Aldosterone antagonism for poorlycontrolled hypertension in type 2 diabetes: conflictingeffects on blood pressure, endothelial function,glycaemic control and hormonal profiles. 096Syed F Acute coronary syndrome (ACS) audit cycle:assessing impact of implementing acs service onmanagement and in-hospital length of stay of patientsadmitted with non-ST segment elevation acute coronarysyndrome (NSTEACS). 072Tan Y Abnormal left ventricular systolic and diastolicfunction on exercise in patients with heart failure andnormal ejection fraction (HFNEF). 208Taylor J Is pre-procedural rotational angiography superiorto conventional, single plane angiography forplanning PCI? 073Teoh M Do patients diagnosed with non-stemi by newESC criteria have the same long term outcome as othermyocardial infarcts? 259Testa L Myocardial infarction after percutaneous coronaryintervention: a meta-analysis of troponin elevationapplying the new universal definition. 250Tharmaratnam D Adverse local reactions to the use ofhydrophilic sheaths for radial artery canulation. 251Thomas H Investigation of relationships betweencirculating endothelial progenitor cell numbers, cardiacallograft vasculopathy and donor heart age in cardiactransplant recipients. 209Thomas H Investigation of endothelial progenitor cellresponses following elective percutaneous coronaryintervention. 026Thomas H Circulating endothelial progenitor cells fromhealthy individuals exhibit diurnal variation. 117Thomas D Optimisation of CRL improves LV diastolicfunction. 179Thomas M Safety of early aeromedical repatriationfollowing acute coronary syndrome. 074Tomaszewski M Estrogens and lipid profile in young men– association analysis. 118Tomlinson D Inter-atrial septal thickness and difficultywith transseptal puncture during catheter ablationof atrial fibrillation. 188Torii R Differences in coronary artery haemodynamicsdue to changes in flow and vascular geometry afterpercutaneous coronary intervention. CTrent R ECGS and reperfusion: do we know whatwe are doing? 033100101

British Cardiovascular Society Annual Scientific Conference 2-4 JuneFirst author indexNotesTurley A 30-day mortality rates for patients admittedwith an acute coronary syndrome. Cumulative funnelplots for two cardiac centres within the north-eastof England. 260Twomey D Aborted myocardial infarction in the primaryPCI era. 270Twomey D Using statistical process control to plotthe door-to-balloon time for data feedback andanalysis in patients presenting with acute myocardialinfarction. 272Twomey D Validation of risk adjustment models formortality following primary percutaneous interventionusing a UK-based data set. 271Valerio C Does minap (myocardial infarction nationalaudit project) accurately record medical practice:a comparison of MINAP data & hospital informationconcerning secondary prevention medication. 075Varghese A Audit of cardiac rehabilitation across theEnglish cardiac networks. 076Veasey R The efficacy of pulmonary vein isolation foratrial fibrillation in patients with implanted permanentpacemakers: the previously paced pulmonary veinisolation (PVI) study. 190Veasey R The usefulness of minimal ventricular pacingand preventive AF algorithms in the treatment of PAF:the minvpace study. 180Veasey R The efficacy of intraoperative atrialradiofrequency ablation for atrial fibrillation duringconcomitant cardiac surgery – the surgical atrialfibrillation suppression (SAFS) study. 189Velavan P Predictors of appropriate shocks andmortality in recipients of implantable cardioverterdefibrillators. 181Venkatachalapathy S Déblocage – off site PCI improvesaccess to revascularisation in acute coronarysyndromes. Result of the study of angiography andrevascularisation in Swindon (STARS) audit. 077Venugopal V Female gender is associated withsignificantly adverse outcome following percutaneouscoronary intervention – data from a contemporary“real-world” registry. 252Viswanathan K BNP is the best single marker forlong-term mortality in ACS. 120Viswanathan K H-FABP is superior to troponin inpredicting long-term mortality in suspected ACSpatients. 119Von Klemperer K Pregnancy outcome in women withsystemic right ventricles – a UK single centre experienceat University College Hospital London NHS Trust. Katevon Klemperer, Ruth Brooks, Justin O’Leary, ShayCullen, Patrick O’Brien, Fiona Walker. 164Webb I Ischaemic preconditioning is not dependent uponGSK-3B inhibition. 027Webb I GSK-3B is not a necessary signalling intermediatein postconditioning. 106Weir R MMP 3 – a predictor of ventricular functionfollowing acute myocardial infarction? 121Williams L Acute haemodynamic effects of cardiacresynchronisation therapy in heart failure with a narrowqrs duration. 210Yadav H Relative right ventricular versus left ventricularfunction in patients who have either had or not hadCABG surgery: a cross sectional study. 137Yeh J Echo identification and quantification ofinflammatory molecules in the heart. 034Zaman M Is the increased cardiovascular mortality insouth asians A result of increased incidence or casefatality? Four new studies and a meta-analysis. 261Zhang W Are indian asians genetically homogeneous?Implications for genetic association studies. 122Zi M Ras-association factor 1 (RASSF1A), a novel regulatorof cardiac hypertrophy. 107102103

British Cardiovascular Society Annual Scientific Conference 2-4 JuneNotes104