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Plant Sterols and Stanols as Cholesterol-Lowering Ingredients in ...

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10 Recent Patents on Food, Nutrition & Agriculture, 2009, Vol. 1, No. 1 Kamal-Eld<strong>in</strong> <strong>and</strong> Moazzami<br />

(Table 2) Contd….<br />

Patent Number Inventors Title Publication Date Described Process<br />

WO07137449 J. Liu<br />

W. U. Shengm<strong>in</strong><br />

US20087368138 C. Abb<strong>as</strong><br />

A.M.<br />

Rammelsberg<br />

K. Beery<br />

US20080015374 D. B. Wiley,<br />

T. A. Dobb<strong>in</strong>s<br />

US20080015367 T. A. Dobb<strong>in</strong>s<br />

D. B. Wiley<br />

D. C. Dobb<strong>in</strong>s<br />

US20087335389 E. P. Lerchenfeld,<br />

D. E. Striegel<br />

US20087329429 M. J. Chimel<br />

J. F.<br />

Hammerstone, J.<br />

C. Johnson, M. E.<br />

Meyers, R. M.<br />

Snyder, E. J. Eric<br />

Compositions for treat<strong>in</strong>g <strong>and</strong><br />

prevent<strong>in</strong>g hyperlipidemia<br />

Extraction of phytosterols<br />

from corn fiber us<strong>in</strong>g green<br />

solvents<br />

Method for the synthesis <strong>and</strong><br />

isolation of phytosterol esters<br />

Process for isolat<strong>in</strong>g<br />

phytosterols <strong>and</strong> tocopherols<br />

from deodorizer distillate<br />

Beverages conta<strong>in</strong><strong>in</strong>g plant<br />

sterols<br />

Bars <strong>and</strong> confectionaries<br />

conta<strong>in</strong><strong>in</strong>g cocoa solids hav<strong>in</strong>g<br />

a high cocoa polyphenol<br />

content <strong>and</strong> sterol/stanol esters<br />

<strong>and</strong> processes for their<br />

preparation<br />

US20080102111 I. Hiromichi Anticancer composition for<br />

oral use compris<strong>in</strong>g liposome<br />

conta<strong>in</strong><strong>in</strong>g phytosterols <strong>and</strong><br />

prevention or treatment for<br />

cancer us<strong>in</strong>g the liposome<br />

US20087368583<br />

T. Czuppon<br />

Z. Kemeny<br />

E. Kovari<br />

K. Recseg<br />

US20080103118 K. Clement<br />

M. A. Heuer<br />

M. Thom<strong>as</strong><br />

E. M<strong>as</strong>on<br />

US20087387786 N. Milste<strong>in</strong><br />

M. Biermann<br />

P. Leidl<br />

R. Von Kries<br />

Process for recovery of plant<br />

sterols from by-product of<br />

vegetable oil ref<strong>in</strong><strong>in</strong>g<br />

Composition for improv<strong>in</strong>g<br />

blood cholesterol levels<br />

Food additive compositions<br />

conta<strong>in</strong><strong>in</strong>g sterol esters,<br />

solubilis<strong>in</strong>g agents,<br />

dispersants <strong>and</strong> antioxidants<br />

December, 2007 Use of a comb<strong>in</strong>ation of plant sterols/stanols (30-50%),<br />

flavones from bamboo leaves (20-40%), procyanid<strong>in</strong>s (10-<br />

25%), <strong>and</strong> beta-glucan (5-20%) for the treatment of<br />

hyperlipidemia (to lower blood cholesterol <strong>and</strong> triacylglycerols)<br />

January, 2008 Use of “green” solvents (e.g. ethanol, isopropyl alcohol, or<br />

butanol <strong>and</strong> their mixtures with water, ethyl lactate, ethyl<br />

acetate, acetone, or isoamyl alcohol) to extract sterols from wet<br />

corn fiber. The result<strong>in</strong>g oil product conta<strong>in</strong>s free plant sterols<br />

<strong>and</strong> free fatty acids<br />

January, 2008 Methods for synthesis <strong>and</strong> isolation of plant sterol esters of<br />

bl<strong>and</strong> t<strong>as</strong>te <strong>and</strong> light color <strong>in</strong>volv<strong>in</strong>g the use of an alkali metal<br />

borohydride to reductively bleach tocoqu<strong>in</strong>ones <strong>and</strong> other<br />

chromophores <strong>in</strong> plant sterol ester transesterification reaction<br />

mixtures.<br />

January, 2008 Recovery of pure plant sterols <strong>and</strong> tocopherols from the<br />

deodorizer distillates of the ref<strong>in</strong><strong>in</strong>g of edible oils after<br />

saponification with pot<strong>as</strong>sium hydroxide <strong>in</strong> methanol/water<br />

followed by distillation of the tocopherols<br />

February, 2008 Preparation of a stable dispersion of hydrophobic plant sterols<br />

<strong>and</strong> an aqueous material where<strong>in</strong> the size of the plant sterol<br />

particles ranges 0.1-30 microns with the majority of particles <strong>in</strong><br />

the range 0.2-10 microns to enhance solubility <strong>in</strong> beverages<br />

Fenruary, 2008 Processes for the preparation of healthy bars of dark <strong>and</strong> white<br />

chocolate with cocoa procyanid<strong>in</strong>s <strong>and</strong> sterol/stanol esters are<br />

described<br />

May, 2008 Use of liposomes conta<strong>in</strong><strong>in</strong>g plant sterols (e.g. �-sitosterol,<br />

campesterol, stigm<strong>as</strong>terol, br<strong>as</strong>sic<strong>as</strong>terol, ergosterol,<br />

ergostadienol, etc.) to <strong>in</strong>hibit cancer met<strong>as</strong>t<strong>as</strong>is<br />

May, 2008<br />

Crystallization of plant sterols from deodorization distillates<br />

from chemical or physical ref<strong>in</strong><strong>in</strong>g of vegetable oils by<br />

distillation <strong>and</strong> saponification of the other components present<br />

May, 2008 A composition of plant sterols. stanols or derivatives thereof<br />

plus procyanid<strong>in</strong>s. policosanol <strong>and</strong> niac<strong>in</strong> or derivatives of<br />

niac<strong>in</strong> to <strong>in</strong>hibit cholesterol absorption, decre<strong>as</strong>e blood LDL<br />

levels, <strong>in</strong>cre<strong>as</strong>e blood HDL levels, <strong>and</strong> <strong>in</strong>hibit HMG-CoA<br />

reduct<strong>as</strong>e activity<br />

June, 2008 Food additive comb<strong>in</strong>ation <strong>in</strong>clud<strong>in</strong>g plant sterols/stanols <strong>and</strong>,<br />

for example, oxides, hydroxides, <strong>and</strong> carboxylic acid salts of<br />

calcium or magnesium are described

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