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CoreModels - Maryland Virtual High School - Montgomery Blair High ...

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Appendix CEnzyme Model—STELLA® EquationsHydrogen_Peroxide(t) = Hydrogen_Peroxide(t-dt)+(- H2O2_Catalysis_Rate) * dtINIT Hydrogen_Peroxide = 1*10^(Hydrogen_Peroxide_Exponent)DOCUMENT: The amount of hydrogen peroxide in this stock is number ofmolecules and not absolute concentration (M). The value is set at more thanthe maximum catalytic rate of catalase at its optimal temperature and pH,which is 6 million H2O2 molecules (see H2O2 Catalysis Rate and H2O2 to Waterflows).OUTFLOWS:H2O2_Catalysis_Rate(o) =min(Enzyme_Rate*Available_Enzyme,Hydrogen_Peroxide)DOCUMENT: The enzyme catalysis rate equals the minimum of the amountof hydrogen peroxide and the catalase catalytic rate multiplied by theamount of available enzyme. Because two molecules of hydrogen peroxideare converted into two molecules of water and one molecule of oxygen (O2),this model uses a conversion multiplier to halve the amount of oxygenaccumulated per catalytic event. (See H2O2 Catalysis Rate (i).)Oxygen(t) = Oxygen(t - dt) + (H2O2_Catalysis_Rate) * dtINIT Oxygen = 0DOCUMENT: The number of oxygen molecules created is one-half the numberof hydrogen peroxide molecules that break down in the reaction. Therefore, themodel uses a conversion multiplier to halve the amount of oxygenaccumulated per catalytic event.INFLOWS:H2O2_Catalysis_Rate(i) = H2O2_Catalysis_Rate(o) * CONVERSIONMULTIPLIERCONVERSION MULTIPLIER = 0.5DOCUMENT: The enzyme catalysis rate equals the minimum of the catalasecatalytic rate multiplied by the amount of available enzyme and theamount of hydrogen peroxide. Because two molecules of hydrogen peroxideare converted into two molecules of water and one molecule of oxygen (O2),this model uses a conversion multiplier to halve the amount of oxygenaccumulated per catalytic event. (See H2O2 Catalysis Rate (i).)Water(t) = Water(t - dt) + (H2O2_to_Water) * dtINIT Water = 0DOCUMENT: The water measured here is metabolic water, water that isproduced from the conversion of hydrogen peroxide by catalase.INFLOWS:H2O2_to_Water = H2O2_Catalysis_RateDOCUMENT: This model "measures" metabolic water because that numberof molecules is equal to the number of H2O2 molecules converted; so H2O2to Water is set to equal H2O2 Catalysis Rate catalysis without a conversionmultiplier.A3

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