First, we listen - The Department of Surgery - University of Chicago

EducationHealingb e g i n s w i t hunderstandingEducation is the cornerstone of the University of Chicago Department of Surgery. The surgical faculty teach andtrain medical students, residents and fellows the most advanced surgical skills, comprehensive medical knowledgeand how to build trusting partnerships with their patients.It all starts with recruiting the best residents and fellows to the Department’s exceptional training programs. Onceagain, the Department has achieved great success with the National Resident Matching Program. During the2011-12 recruitment season, the Department’s six first-year general surgery residents matched in the top third inthe Department’s highly competitive match list. This recruitment success has been equally strong in Cardiac andThoracic Surgery, Neurosurgery, Ophthalmology and Visual Science, Orthopaedic Surgery and RehabilitationMedicine, Otolaryngology-Head and Neck Surgery, Pediatric Surgery, Plastic and Reconstructive Surgery, Transplantation,Urology and Vascular Surgery and Endovascular Therapy.Beyond recruitment, the Department continues to evolve its programsto meet the needs of the residents. Among these efforts is the developmentand implementation of the Team Education Coordinator (TEC)system. Educational leadership selects a TEC for each clinical serviceline based on their leadership skills and commitment to education. TheTEC serves an important role in the process of program evaluationand improvement. Each TEC assumes responsibility for developingthe curriculum for the service, resident assessment, monitoring dutyhours and informing faculty of new policies and procedures. Twice ayear, the TEC reviews the resident evaluations of the clinical serviceand the faculty. This allows for a more formal process of reviewingprograms as well as reviewing and responding to residents’ commentsand incorporating their feedback into change.TECs from the University of Chicago include:• Nora Jaskowiak, MD – Kaplan Service• Mukta Krane, MD – Block Service F (1)• Konstantin Umanskiy, MD – Block Service H (2)• Kevin K. Roggin, MD – Dragstedt Service• Vivek N. Prachand, MD – Ferguson Service• Christopher L. Skelly, MD – Vascular Surgery andEndovascular Therapy• Eugene Choi, MD – Night Float• John Renz, MD, PhD – Transplantation• Grace Mak, MD – Pediatric Surgery• Mark Ferguson, MD – Cardiac & Thoracic Surgery• Lawrence J. Gottlieb, MD – Burn• Gary C. An, MD – Intensive Care UnitThe Department of Surgery intern class of 2011TECs from NorthShore University HealthSystem include:• Marshall Baker, MD – Hepatobiliary Surgery• David J. Winchester, MD – Surgical Oncology• Joseph Muldoon, MD – Colon and Rectal Surgery• Michael Ujiki, MD – Minimally Invasive Surgery• Omar Morcos, MD – Vascular SurgeryIn addition to changes in the structure, the Open Surgical SkillsCurricula for PGY-1 and PGY-2/3 residents have undergone somesignificant changes that will enhance residents’ education and learningexperiences. The PGY-1 curriculum, under the planning and direction ofKonstantin Umanskiy, MD, will be centered around the basic surgicalskills such as knot tying, instrument identification, suturing, placingcentral lines and inserting chest tubes. The PGY-2/3 curriculum,under the direction of Katherine Yao, MD, (NorthShore UniversityHealthSystem) will include modules on advanced surgical skills,advanced instrument identification and labs for intestinal anastomoses.The program will take advantage of the state-of-the-art facilities ofboth the University of Chicago Simulation Center and the NorthShoreUniversity HealthSystem’s Center for Simulation and Innovation. Itwill add to the already existing laparoscopy curricula that are underthe direction of Vivek N. Prachand, MD, and Michael Ujiki, MD(NorthShore University HealthSystem).Residents and fellows are not the only ones who benefit from learning.During the winter and spring quarters, Department faculty hadthe opportunity to participate in a six-month course on TeachingEffectiveness, offered by Nancy Schindler, MD, Associate Director ofSurgical Education. The course was designed to help faculty improvetheir teaching skills. Course topics were chosen based on a needsanalysis including results of resident and student evaluations and facultyevaluations of the program. Faculty participated in five 90 minuteJoseph Pariser, MD, (left) at the University of Chicago Pritzker School ofMedicine Match Dayworkshops, including Feedback, The One Minute Teacher, Teachingin the Ambulatory Setting, Large Group Teaching, and The Scholarshipof Teaching. The program required a substantial commitment of timeon the part of the faculty. They demonstrated great enthusiasm fortheir roles as teachers. Participants included: Kevin K. Roggin, MD,Wickii T. Vigneswaran, MD, Darwin Eton, MD, Eugene Choi, MD,and Konstantin Umanskiy, MD.All of these changes have played a significant part in the Section ofGeneral Surgery receiving the full five year accreditation with no citationfrom the Accreditation Council for Graduate Medical Education(ACGME) Residency Review Committee, and the Surgical Oncologyprogram receiving the full five year accreditation with no citationfrom the Society of Surgical Oncology in 2011.4 The University of Chicago Department of Surgery2011 Annual Report 5

Researchunderstandingb e g i n s w i t hDiscovery“Discovery is our business,” said Charles B. Huggins, MD, the 1966 Nobel Prize winner for hormonal treatment ofprostate cancer. This statement rings true for research in the University of Chicago Department of Surgery. Frombasic science to clinical investigations, the Department is pioneering a wide range of research that is transformingthe field of surgery.Vaccination is the most effective means for the prevention of disease, but numerous challenges are faced by bothwhole cell vaccines and protein-based alternatives, which require adjuvants to enhance their effectiveness. JoelCollier, PhD, and Anita S. Chong, PhD, continue their research collaboration in developing vaccine candidatesfor several diseases, including Staphylococcus aureus. In their research, Dr. Collier’s lab has designed anddeveloped a self-assembling peptide system that, when coupled with peptide antigens, creates a strong immuneresponse without the need for additional adjuvant, a substance that provokes an immune response and for thisreason is used in synthetic vaccines and immunotherapies. The importance of this innovative line of research ishighlighted by its recent publication in the prestigious journal Proceedings of the National Academy of Sciences(PNAS), and its recent funding award from NIH in 2011.Transmission electron microscope image of a self-assembled peptide nanofiberadjuvant system under investigation in the labs of Drs. Collier and ChongShahab A. Akhter, MD, and John C. Alverdy, MD, have formed acollaboration to investigate the potential beneficial effects of highmolecular weight PEG-based polymers in protecting the heart fromischemia-reperfusion injury. Dr. Alverdy’s lab has previously discoveredthat these synthetic polymers can protect intestinal epithelial cells invitro and in the gut from various types of injurious stimuli throughbinding and stabilization of lipid raft domains and preserving membraneintegrity and architecture. Dr. Akhter’s group, which studies Gprotein-coupled receptor signaling in the heart, has recently shownthat PEG-based polymers are very effective in protecting isolatedcardiac myocytes and the heart in vivo from ischemia-reperfusioninjury through stabilization of lipid raft domains and upregulation ofcell survival signaling.A demonstration of advanced surgical robotics at the University of Chicago BIASE Symposium in December 2010Further investigation into the molecular mechanisms for polymer-basedcellular protection and optimization of polymer structure are areas ofongoing collaborative research. This work has great translational potentialto minimize or inhibit myocardial damage following revascularizationin the setting of acute coronary ischemia and to improve myocardialprotection during cardiac surgery including heart transplantation.Dr. Alverdy’s lab also has a long-standing interest in the role ofmicrobes/bacteria in surgical diseases. His lab has developed capabilitiesto genetically interrogate and sequence bacteria to define its rolein diseases such as sepsis. Christopher L. Skelly, MD, has researchinterests in identifying the role of microbes in vascular diseases such asintimal hyperplasia, a disease in which scar tissue forms and re-blocksthe artery. Dr. Skelly is investigating the role that microbes, includingbacteria and viruses, may play in the development of atherosclerosisand aneurismal degeneration of blood vessels.The Department hosted a two-day interactive meeting in December2010 in the Dennis and Claire Nardoni Conference Center and theUniversity of Chicago Simulation Center. This event was jointlypresented by the University of Chicago-Argonne National LaboratoryBioengineering Institute for Advanced Surgery and Endoscopy(BIASE), iSurgitec and the University of Chicago Simulation Center.The purpose of the meeting was to generate new lines of inquiry andtechnical approaches to define and solve critical challenges facingsurgeons. Some of the themes included molecular and mechanicalmechanisms of anastomotic healing and breakdown, novel molecularand modeling-based approaches to understand tissue healing andinfection, and emerging methods to improve reliability and reducepatterns of failure in complex high-tech environments. Along withpresentations from leading experts in the field, the event included livedemonstrations of innovations in surgical stapling, advanced surgicalrobotics, innovations in surgical thread tensions and an ImmersiveTouch ® 3-D Surgical Simulator.Close up of the robotic arms6 The University of Chicago Department of Surgery2011 Annual Report 7

SPONSORED RESEARCHPrincipal Investigator Research Title GrantCardiac and Thoracic SurgeryShahab A. Akhter, MD Myocardial Regulation of BETAARK1 by Protein Kinase C Federal & Non-federalMark K. Ferguson, MDInhibition of GRK2 to Prevent Ventricular Remodeling and Heart Failure After CABGA Double-Blind, Randomized, Placebo-Controlled Phase III Study to Assess the Efficacyof recMAGE-A3 + AS15 Antigen-Specific Cancer Immunotherapeutic as AdjuvantTherapy in Patients with Resectable MAGE-A3-positive Non-Small Cell Lung CancerA Randomized Phase III Trial of Adjuvant Chemotherapy in Patients With EarlyStage Non-Small Cell Lung Cancer Associated With Banking of Frozen Tumor Specimensand Collection of Gene Expression Profile DataFederalClinical TrialClinical TrialMahesh P. Gupta, PhD The Role of PARP-SIR2 Signaling in Heart Failure FederalValluvan Jeevanandam, MDGeneral SurgeryJohn C. Alverdy, MDReversible Acetylation of Glycogen Synthase Kinase Regulates theDevelopment of Cardiac HypertrophyEvaluation of the HeartWare® Ventricular Assist System for the Treatment ofAdvanced Heart Failure - Continued Access ProtocolA Prospective, Randomized, Controlled, Un-blinded, Multi-Center Clinical Trialto Evaluate the HeartWare Ventricular Assist System for Destination Therapy ofAdvanced Heart FailureInteragency Registry of Mechanically Assisted Circulatory SupportInvestigation of Host-Pathogen Interactions, Conserved Cellular Responses andCountermeasure Efficacy During Spaceflight Using the Human Surrogate ModelCaenorhabditis ElegansPseudomonas' Effects on the Gut Barrier from SurgeryNon-FederalClinical TrialClinical TrialClinical TrialFederalFederalGary C. An, MD Molecular Biology of Hemorrhagic Shock FederalRehabilitation Engineering Research Center (RERC) on Spinal Cord InjuryEMT/BSSE: Hierarchical Representation and Simulation of Modular Cellular SystemsFederalNon-federalPeter Angelos, MD, PhD American College of Surgeons Oncology Group (ACOSOG) - Ethics Committee FederalEugene Choi, MD LET-7 Regulation of Metastasis in Pancreatic Cancer Non-federalAlessandro Fichera, MD Perianal Dermatitis in Patients After Ileal Pouch Anal Anastomosis for Ulcerative Colitis Non-federalA Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate theEfficacy and Safety of Intravenous (IV) Ulimorelin Administered Post-Operatively toAccelerate Recovery of Gastrointestinal (GI) Motility in Subjects Who Have UndergonePartial Bowel ResectionA Phase III Prospective Randomized Trial Comparing Laparoscopic-Assisted ResectionVersus Open Resection for Rectal CancerPhase II Trial of Neoadjuvant Chemoradiation and Local Excision for UT2uNo RectalCancerClinical TrialClinical TrialClinical TrialJose Guevara-Patiño, MD, PhD Targeting HSP70 in Autoimmune Vitiligo FederalDNA Vaccine for Seasonal and Pandemic InfluenzaFunctional Profiling of Tumor-Induced Immune SuppressionFederalNon-federalNora Jaskowiak, MD Chicago Specialized Programs of Research Excellence in Breast Cancer FederalMarco G. Patti, MD Minimally Invasive Educational Support Agreement Non-federalMitchell C. Posner, MD American College of Surgeons Oncology Group (ACOSOG) FederalKevin K. Roggin, MDNeurosurgeryAmerican College of Surgeons Oncology Group (ACOSOG) and the ACOSOGStatistics and Data Coordination CenterA Comprehensive Program in Pancreatic Cancer Prevention and Early DetectionDevelopment of a Novel Molecular Fingerprinting to Aid in the Early Detection ofPremalignant and Invasive Malignant Pancreatic Cystic NeoplasmsFederalNon-federalNon-federalIssam A. Awad, MD, MSc, MA (hon) Clot Lysis: Evaluating Accelerated Resolution of IVH Phase II (CLEAR III) FederalGenesis and Progression of Cerebral Cavernous MalformationsICH Removal: Minimally Invasive Surgery + rt-PAFederalFederalIrina Balyasnikova, PhD Non-Invasive Delivery to Stem Cells as Therapeutic Vehicles to the Brain Tumors Non-federalNovel Tumor Selective TRAIL Fusion Protein for Treatment of the Brain TumorNon-federalDavid M. Frim, MD, PhD Automated Ventricular Analysis FederalPrincipal Investigator Research Title GrantMaciej S. Lesniak, MD Conditionally Replicative Adenoviral Vectors for Malignant Glioma FederalGenetically-Modified Neural Stem Cell Based Virotherapy for Invasive GliomasThe Role of Regulatory T Cells in Malignant GliomaTargeted Adenoviral Gene Therapy for Malignant GliomaFederalFederalNon-FederalCatherine Ojakangas, PhD Cerebral Mechanisms of Skill Learning in Humans FederalChangbin Shi, MD, PhD Pathogenetic Antigen in Human Cerebral Cavernous Malformation Non-FederalBakhtiar Yamini, MDCollaborative Research: Mathematical Optimization for Targeted Macro-MoleculesDelivery to the BrainNF-KB1-P50 in the Response to DNA Akylation DamageNanoparticles and Nanocapsules for Glioma TargetingNF-KB1-P50 and the Response of Gliomas to TemozolomideOphthalmology and Visual ScienceTemozolomide and Nuclear Factor-kB in the Treatment of Malignant GliomaFederalFederalFederalNon-FederalNon-FederalDingcai Cao, PhD Rod Cone Interactions in Mesopic Vision FederalMichael Grassi, MDSeenu M. Hariprasad, MDThe Chicago Retinal Degeneration Consortium: Advancing a Systems-Based Approachto Understanding & Treating Retinal Degenerative DiseaseCellular Studies of Apoptosis in Retinitis Pigmentosa Using Small Molecular Screeningand RNA InterferenceA Multicenter Randomized Study Evaluating Dosing Regimens for TreatmentWith Intravitreal Ranibizumab Injections in Subjects With Macular Edema FollowingRetinal Vein OcclusionA 6-month, Phase II, Double-Masked, Multicenter, Randomized, Placebo Controlled,Parallel Group Study to Assess the Safety and Efficacy of Topical Administration of TwoConcentrations of FOV2304 (1% and 2%) Twice Daily for the Treatment of Center-Involving Clinically Significant Macular Edema Associated with Diabetic RetinopathyA Phase III, Double-Masked, Multicenter, Active Treatment-Controlled Study ofthe Efficacy and Safety of 0.5 mg and 2.0 mg Ranibizumab Administered Monthlyor on an As-Needed Basis (PRN) in Patients with Subfoveal Neovascular Age-RelatedMacular DegenerationNon-federalNon-federalClinical TrialClinical TrialClinical TrialSusan Ksiazek, MD Student Sight Saver Program Non-federalRima McLeod, MD Towards a Vaccine to Prevent Toxoplasmosis FederalOptimizing Inhibitors of T. Gondii ENRTreatment of Congenital ToxoplasmosisDevelopment of an Inhibitor for Toxoplasma GondiiInnate Immune Receptors for Toxoplasma GondiiOrthopaedic Surgery and Rehabilitation MedicineFederalFederalFederalFederalRex C. Haydon, MD, PhD Effect of ADBMP Gene Therapy and PRP in a Rat Rotator Cuff Model Non-federalTong-Chuan He, MD, PhD Regulation of Beta-Catenin Signaling by Tyrosine Phosphorylation FederalCenter for Herbal Research on Colorectal CancerRole of IGFBP5 in Osteogenic DifferentiationFederalNon-federalSherwin Ho, MD OREF Clinical Development Program Non-federalHue H. Luu, MD The Role of Connective Tissue Growth Factor on BMP9-Induced Osteogenesis FederalDaniel P. Mass, MD Total Wrist Replacement, a Multi-center Study Clinical TrialBrian Toolan, MD Resident Journal Club Grant Non-Federal2011-2012 Residency Enhancement Grants Non-FederalOtolaryngology-Head and Neck SurgeryJacquelynne Corey, MD Immunology for the Otolaryngologist Non-FederalRobert Naclerio, MDA Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial ofTopical Allstate in the Prevention of the Signs and Symptoms of the AcuteResponse to Nasal Allergen ChallengeEvaluation of NasoNeb Delivery of an Intranasal Steroid in the Treatmentof Perennial Allergic RhinitisClinical TrialClinical TrialJayant Pinto, MD Pediatric Asthma Network Data Coordinating Center (Mist-Microbiome Project) FederalCTSA K12 ScholarsNon-Federal8 The University of Chicago Department of Surgery2011 Annual Report 9

Principal Investigator Research Title GrantPediatric SurgeryMichael Morowitz, MD Population Genomic Analysis of Gut Microbial Colonization in Premature Infants FederalPathogenicity of Intestinal Microbes in Milk-Fed and Formula-Fed Premature Infants Non-FederalPlastic and Reconstructive SurgeryRaphael C. Lee, MD, ScD, DSc(hon) Biopolymer Surfactants for Sealing Electroporated Membranes FederalRussell R. Reid, MD, PhD Differential Effects of BMPs on the Healing of Craniofacial Defects FederalThe Role of RANK Signaling in Cranial Suture HomeostasisNon-FederalThe Use of Pulsed Electromagnetic Fields for the Enhancement of theConsolidation Period of DistractionNon-FederalResearchJoel Collier, PhD Modular Self-Assembled Coatings for Biomaterials FederalKathleen Goss, PhDSynthetic Protein and Peptide Assemblies as Novel Adjuvants and VaccinesCAREER: Modular Assemblies for Controlling The Cell-Material InterfaceNanomaterials for Cancer Diagnostics and TherapeuticsCrosstalk Between the BRCA2 and APC/Beta-Catenin Pathways in Mammary StemCells and Breast Cancer (co-PI)Impact of APC Loss in Mouse Models of Human Breast CancerFederalNon-federalNon-FederalNon-federalNon-FederalKarl S. Matlin, PhD Cell-Matrix Interactions in Epithelial Polarization FederalA History of Cell Biology from the Perspective of the Signal HypothesisFederalMirjam Zegers, PhD Regulation of Epithelial Contact Inhibition by RAC Effector Proteins FederalTransplantationAnita S. Chong, PhD B Cells in Transplantation Tolerance FederalDevelopment of Two Alloreactive BCR-TG Mouse StrainsMechanistic Studies on Listeria Infection and Inhibition of Allograft ToleranceBacterial Infection and Transplantation ToleranceEffect of Alogliptin on Beta Cell RegenerationMechanisms of Type 1 Interferon Signaling in Preventing TransplantationTolerance Induced by Co-Stimulation BlockageFederalFederalNon-federalNon-federalNon-federalJ. Michael Millis, MD The Transplantation in People with HIV Infection FederalA Randomized, Open Label, Parallel-Group, Multi-center Trial to Compare the Efficacyand Safety of TachoSilÒ versus SurgicelÒ Original for the Secondary Treatment ofLocal Bleeding in Adult and Pediatric Patients Undergoing Hepatic Resection Surgery(TC-2402-040-SP)A 24 Month Multi-center, Open-Label, Randomized, Controlled Study toEvaluate the Efficacy and Safety of Concentration-Controlled Everolimus to Eliminateor to Reduce Tacrolimus Compared to Tacrolimus in De Novo Liver Transplant Recipients(CRAD001H2304)Clinical TrialClinical TrialRoger Sciammas, PhD IRF4 as a Molecular Gatekeeper of Effector B Cell Fate and Growth Non-federalJ. Richard Thistlethwaite, Jr.,MD, PhDTracking B and Plasma Cell Functions During Transplant RejectionBelatacept Evaluation of Nephroprotection and Efficacy as First-LineImmunosuppression Trial- EXTended Criteria DonorsBelatacept Evaluation of Nephroprotection and Efficacy as First-LineImmunosuppression TrialNon-federalClinical TrialClinical TrialPrincipal Investigator Research Title GrantUrologyScott Eggener, MDCarrie W. Rinker-Schaeffer, PhDGary D. Steinberg, MDDonald J. Vander Griend, PhDThe Men's Eating and Living (MEAL) Study: A Randomized Trial of Diet to AlterDisease Progression in Prostate Cancer Patients on Active SurveillanceIdentifying the Mechanism(s) Responsible for the Translational Regulation of the StressSignaling Kinase MKK4The Role of the Omental Microenvironment in Ovarian Cancer Metastatic ColonizationThe Role of Receptor Sialylation in the Ovarian Tumor Cell PhenotypeProstate Cancer Mestastatic Colonization: Role of MKK4Milky Spot Macrophages: Co-Conspirators in Omental Metastasis FormationRECOVERY-Tissue Source Site (TTS) in Support of Cancer Genome Atlas (TCGA)ProgramEvaluation of the UroVysion Test in Predicting Recurrence and/or Progression ofDisease in Patients Receiving Initial BCG or BCG plus Interferon Therapy for PrimaryHigh Grade Papillary and CIS Urothelial Carcinoma of the BladderA Phase I Open Label Exploratory Study of an Autologous Neo-Urinary Conduit inSubjects Requiring Incontinent Urinary Diversion Following Radical CystectomyA Phase III, Randomized, Active-Controlled, Open-Label, Multicenter Study to Evaluatethe Efficacy and Safety of EN3348 (MCC) as Compared with Mitomycin C in theIntravesical Treatment of Subjects with BCG Recurrent or Refractory Non-MuscleInvasive Bladder CancerAndrogen Independence and Gene Expression Analyses of CD133-Positive ProstateCancer Stem CellsFunction of the Stem Cell Marker CD133 in the Progression of Castrate-ResistantProstate CancerHuman Prostate Stem Cells in Prostate DiseasesClinical TrialFederalFederalFederalFederalNon-federalFederalClinical TrialClinical TrialClinical TrialNon-FederalNon-FederalNon-federalGregory Zagaja, MD Phase II Clinical Trial of Polyphone E in Prostate Cancer FederalRandomized Placebo Controlled Adjuvant Study of Prevention of Prostate CancerRecurrence after Radical Prostatectomy by Soy Protein IsolatePhase II, Randomized, Double-Blind, Multi-centered Study of Polyphenon E in Menwith High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) and Atypical SmallAcinar ProliferationRandomized Controlled Trial of Early Removal of Urethral Catheter with SuprapubicTube Drainage Versus Urethral Catheter Drainage Alone Following Robot-AssistedLaparoscopic Radical ProstatectomyVascular Surgery and Endovascular TherapyFederal/Clinical TrialClinical TrialClinical TrialChristopher L. Skelly, MD Herpes Simplex Virus Therapy for the Treatment of Neointimal Hyperplasia Federal & Non-federalStenting and Angioplasty With Protection in Patients at High-Risk for EndarterectomyClinical Trial10 The University of Chicago Department of Surgery2011 Annual Report 11

Community OutreachHealinglocal and globalcommunitiesHealing goes beyond the walls of the hospital and out into the local and global communities. Many of theDepartment of Surgery’s faculty members volunteer their time and surgical expertise to improve the health ofpeople living here and abroad.The University of Chicago Departments of Surgery, Anesthesia & Critical Care, and Perioperative Services puttogether their first-ever benefit concert, “Lend an Ear,” at the University of Chicago International House in January2011. Faculty and staff members from these Departments formed a band called “Turnover Time.” The band membersincluded: Shahab A. Akhter, MD (drums); John C. Alverdy, MD (keyboard); James Anderson (vocals); KevinJohnson (vocals); Jeffrey B. Matthews, MD (guitar); Joan Matthews, MD (bass); Jono Matthews (guitar); SarahPae, MD (vocals); and Nikki Phillips (vocals).Handprints of campers from the fourth annual Discover CampThe proceeds from this benefit supported Medical Aid for Childrenof Latin America (MACLA). David H. Song, MD, MBA, an activevolunteer and member of the Board of Directors for MACLA, anda team of surgeons and anesthesia providers travel annually to theDominican Republic to provide free surgical care to children withcongenital deformities, such as absent or malformed ears, cleft lipsand palates and burn scar contractures. The fundraiser was a hugesuccess. The concert drew over 400 people, raised over $23,000 fromthe door contributions and silent auction items and nearly $25,000in online contributions.The fourth annual Discover Camp for children with Chiari Malformation,Spina Bifida and other Neurosystem congenital anomalies washeld in July 2011. The camp is sponsored by pediatric neurosurgeonDavid M. Frim, MD, PhD, who works with many of these families,as an opportunity to enjoy summertime activities in a safe andsupportive environment.“Turnover Time” headlined a fundraising concert for Medical Aid for Children of Latin America (MACLA)The Section of Urology has once again participated in the Indianapolis500 Mini-Marathon in May 2011 to raise funds to support the UrologyResearch Program. This was their sixth year participating in the eventas the “Urinary Track Team.”A couple of times a year, cardiac surgeon Valluvan Jeevanandam,MD, travels to a charity hospital in Puthaparthi, India for one to twoweeks at a time to provide free cardiac surgery, with an emphasis oncomplex cases. On these trips, he performs upwards of 20 charitycases per week to those who cannot otherwise afford care. WithoutDr. Jeevanandam’s help, most patients often face a life expectancy ofless than one year and have no other treatment options. Additionally,Dr. Jeevanandam trains local surgeons to do these complex cardiacsurgeries so they can better serve their communities.Through the auspices of Health Volunteers Overseas, orthopaedicsurgeon Daniel Mass, MD, and hand fellow Hussein Turki, MD,treated hand patients in Lima, Peru. This was Dr. Mass’ 14 th volunteertrip to Peru. Drs. Mass and Turki performed surgical procedures,including pollicizations, several muscle transfers for brachial plexuspalsies, trauma reconstructions after crush injuries as well as tendontransfers for nerve palsies. Dr. Mass also trained local physiciansinterested in hand surgery. Topics included rheumatoid arthritis,tendon transfers, wrist arthroscopies, distal radius fractures, traumareconstruction and replantation.The Section of Urology raised funds to support the Urology Research Program byrunning as the “Urinary Track Team” in the Indianapolis 500 Mini-Marathon12 The University of Chicago Department of Surgery2011 Annual Report 13

SELECTED HONORS 2011–2012Cardiac & Thoracic SurgeryRoger Hurst, MDSusan Ksiazek, MDPurnendu Gupta, MDJohn Martell, MDJacquelynne Corey, MDShahab A. Akhter, MDElected membership, American Association forThoracic SurgeryEditorial Board, PLoS ONEMark K. Ferguson, MDProgram Director, University of Chicago Residencyin Cardiothoracic SurgeryEditorial Board, Journal of Clinical OncologyExecutive Director, International Society for Diseasesof the EsophagusBoard of Directors, CTSNetValluvan Jeevanandam, MDMember, FDP Device PanelEditorial Board, International Society for Heart andLung TransplantationRicky Malhotra, PhDFaculty Award for Clinical/Translational Research,18th Annual Charles B. Huggins ResearchSymposium, The University of Chicago Departmentof SurgeryWickii T. Vigneswaran, MDAmerica’s Top Doctors, Castle Connolly Medical Ltd.Chair, Board of Trustees, International College ofSurgeons U.S. SectionGerhard Ziemer, MD, PhDEditoral Board, World Journal Pediatric andCongenital Heart SurgeryGeneral SurgeryJohn C. Alverdy, MDRobert Baker Golden Apple Award for Excellence inTeachingSecretary, Surgical Infection SocietyGary C. An, MDEditorial Board, ShockEditorial Board, Computational and MathematicalMethods in MedicinePeter Angelos, MD, PhDThird Annual Faculty Physician Peer Role ModelAward, The University of Chicago Roadmap toProfessionalism Steering CommitteeAmerica’s Top Surgeons, Consumer’s ResearchCouncil of AmericaEditor, Surgery News, Ethics SectionAlessandro Fichera, MDWinner, Chicago Surgical Society Resident ResearchAward (Presenter: Jennifer Holder-Murray, MD)Best Video Award, American Society of Colon andRectal Surgery Annual Meeting, Vancouver, B.C.,May 2011Editorial Board, World Journal of GastroenterologyEditorial Board, World Journal of GastrointestinalPathophysiologyEditorial Board, Journal of Gastrointestinal SurgerySESAP 15 Authoring CommitteeNora Jaskowiak, MDFavorite Faculty Award, The University of ChicagoPritzker Medical School Class of 2011Edwin L. Kaplan, MDAmerica’s Top Surgeons, Consumers’ ResearchCouncil of AmericaJeffrey B. Matthews, MDPresident-Elect, Society for Surgery of the AlimentaryTractCo-editor, Journal of Gastrointestinal Surgery57th Samuel Clark Harvey Memorial Lecture, YaleUniversityMarco G. Patti, MDPresident, International Society for Digestive SurgeryCouncilor, Metropolitan Chicago Chapter ACSMitchell C. Posner, MDBest Doctors in America, Best Doctors, Inc.America’s Top Doctors, Castle Connolly Medical Ltd.America’s Top Doctors for Cancer, Castle ConnollyMedical Ltd.Chicago’s Top Doctors, Chicago magazineKevin K. Roggin, MDTop Tier MD, Northshore magazineNeurosurgeryDavid M. Frim, MD, PhDScientific, Educational, and Advisory Board, TheChiari and Syringomyelia FoundationBoard of Directors, Inter-Urban NeurosurgicalSocietyMaciej S. Lesniak, MDExecutive Committee, International Society forTranslational MedicineEditorial Board, Antibody Technology JournalBen Z. Roitberg, MDEditor-in-Chief, Neurological ResearchPeter Warnke, MDEditorial Board, Journal of Alzheimer’s Disease andParkinsonismOphthalmology and VisualScienceSeenu M. Hariprasad, MDEditorial Advisory Board, American Journal ofOphthalmologyAmerica’s Top Ophthalmologists, Consumers’Research Council of AmericaTop Doctor Award, U.S.News & World ReportPatient’s Choice Award, OphthalmologyChicago Top Doctors Award135 Leading Ophthalmogists in America, Becker’sASC ReviewOrganizer and Presenter, 32nd Annual Upper MidwestNeuro-Ophthalmology Group MeetingRima McLeod, MDBest Doctors in the U.S.Thomas Patrianakos, DOAmerica’s Top Ophthalmologists, Consumers’Research Council of AmericaPresident’s Award, Monthly Meeting Chair, TheChicago Ophthalmological SocietyLouise Sclafani, ODWritten Exam Diplomate Chair, Cornea, ContactLens and Refractive Technology Section, AmericanAcademy of OptometryMember at Large—President Elect, Women of Visionin OptometryProfessional Advisory Council Optometric Chair,Chicago Light House for the Blind and VisuallyImpairedSteven K. Shevell, PhDVerriest Medal, International Colour Vision SocietyProfesseur Invité, Laboratoire Psychologie de laPerception Université Paris (Descartes) & CNRS,FranceChiara Fama Scholar, Università degli Studi diFirenze, ItalyProfesseur Invité, Université de Nantes, FranceFellow, Association for Research in Vision andOphthalmology (ARVO)Guest Editor, 50th Anniversary Issue of VisionResearchOrthopaedic Surgery andRehabilitation MedicineJovito Angeles, MDFellow, American Academy for Cerebral Palsy andDevelopment MedicineReader Advisory Board, Journal of Bone and JointSurgeryRobert Bielski, MDBoard Examiner, American Board of OrthopaedicSurgeryRoderick Birnie, MDPresident, Chicago Society for Surgery of the HandHenry Finn, MDWilkes University Health Sciences DistinguishedService AwardTop Docs for Jocks (Orthopaedics), Chicago magazineEditorial Board, Journal of ArthroplastyErgonomic Consultant for General Motors, FordMotor Company and Honda of AmericaBoard Examiner, American Board of OrthopaedicSurgeryTerminology Committee for the Scoliosis ResearchSocietyEditor: The Spine Journal, American Journal of SportsMedicine, Archives of Physical Medicine and Rehabilitation,Biomechanics, Clinical Orthopaedics and Related ResearchRex C. Haydon, MD, PhD2011 Gerald R. Laros, MD, Teaching Award, TheUniversity of ChicagoKeynote Speaker, The University of Chicago PritzkerSchool of Medicine White Coat CeremonyAssociate Editor, Current Orthopaedic PracticeTong-Chuan He, MD, PhDEditorial Board: Recent Patent Reviews on Anti-Cancer Drug Discovery, Laboratory Investigation, TheOpen Cancer Journal, The Open Tissue Engineering andRegenerative Medicine Journal, World Journal of StemCells, World Journal of Biological Chemistry, World Journalof Orthopaedics, American Journal of Stem CellsGuest Editor, Current Gene TherapySherwin Ho, MDOfficial Spokesperson, American Academy ofOrthopaedic SurgeonsBoard of Directors, Education Committee, IllinoisAssociation of Orthopaedic SurgeonsJ. Martin Leland III, MDAmerican Orthopaedic Society for Sports MedicineSelf-Assessment CommitteeInstructor, Orthopaedic Learning Center, Rosemont, ILHue Luu, MDAmerican Academy of Orthopaedic Surgeons/Orthopaedic Research Society Traveling FellowshipAdvisory Committee for Operative ProductsEvaluation Committee, The University of ChicagoAdvisory Committee for the Institute for TranslationalMedicine Internal Scientific Advisory Panel,The University of ChicagoAdvisory Panel, American Academy of OrthopaedicSurgeons/American Dental Association Work Groupfor Guidelines on Antibiotic Prophylaxis for Patientswith Permanent ImplantsDavid Manning, MDCommittee Chair, Resident Recruitment, OrthopaedicSurgery Residency Program, The University ofChicagoModerator, Back to Basics Hip and Knee Course,Complications in Hip Arthroplasty, Mid-AmericaOrthopaedic Association Annual MeetingAdult Reconstruction Hip Sub-Committee, AmericanAcademy of Orthopaedic SurgeonsDirector, Third Year Medical Student OrthopaedicSurgery Rotation, The University of Chicago PritzkerSchool of MedicineDirector, Fourth Year Medical Student OrthopaedicSurgery Sub-Internship, The University of ChicagoPritzker School of MedicineNominee, The American Orthopaedic Association’sDistinguished Contributions to Orthopaedics AwardDaniel P. Mass, MDTop Orthopaedic Surgeon, Leading Physicians of theWorldTop Orthopaedic Surgeon, Who’s WhoTerrance D. Peabody, MDFirst President-Elect, American OrthopaedicAssociationChair, Academic Leadership Committee, AmericanOrthopaedic AssociationBruce Reider, MDEditor, American Journal of Sports MedicineBoard of Directors, American Orthopaedic Societyfor Sports MedicineConsultant Editor, Post-Grad Advances in SportsMedicine, Publisher Forum Medicus, Inc.Reviewer, Clinical Journal of Sports Medicine(Canada), AAOS Sports Medicine Evaluation,Orthopaedics Today, Arthroscopy, ClinicalOrthopaedics and Related ResearchEditorial Board, Operative Techniques in SportsMedicineExecutive Editor, Sports Health: A MultidisciplinaryApproachChristopher Sullivan, MD2010 Family Defender Award, Family Defense CenterBrian Toolan, MDOral Examiner, Part II Oral Boards and Oral Recertification,American Board of Orthopaedic SurgeryAssistant Editor, Current Concepts & TopicalReviews Committee, Foot and Ankle InternationalEducation Committee, Mid-America OrthopaedicAssociation (MAOA)Evidence-Based Practice Committee, AmericanOrthopaedic Foot and Ankle SocietyFoot and Ankle Subcommittee, American Academyof Orthopaedic SurgeonsSelection and Fund Raising Committee, LouisAugust Jonas FoundationKnowledge & Skills Subcommittee, AmericanOrthopaedic AssociationOtolaryngology-Head andNeck SurgeryFuad Baroody, MDBest Doctors in America Database 2011Top Doctor for Kids, Chicago magazineChair, Immunotherapy, Rhinitis, Sinusitis, OcularAllergy and Cough (IRSOC) interest section of theAmerican Academy of Allergy Asthma and ImmunologySecretary, Immunotherapy, Rhinitis, Sinusitis, OcularAllergy and Cough (IRSOC) interest section of theAmerican Academy of Allergy Asthma and ImmunologyChair of the Rhinitis, Sinusitis and Ocular AllergyCommittee of the American Academy of AllergyAsthma and ImmunologyEditorial Board, International Journal of OtolaryngologyTop Doctors (Chicago)Advisory Board, Merck U.S. Allergy ImmunotherapyOtolaryngologistJayant Pinto, MDPoster Award, 18th Annual Charles B. HugginsResearch Symposium, The University of ChicagoDepartment of SurgeryARTrust TM Award, American Academy of Allergy,Asthma and ImmunologyCertificate of Merit, American Roentgen Ray SocietyKL2 Scholar, Institute of Translational Medicine, TheUniversity of ChicagoKerstin Stenson, MDFellow at Large, American Head and Neck SocietyCouncilEditorial Board, Head and Neck JournalPediatric SurgeryDonald C. Liu, MD, PhDEditorial Board Member at Large, Journal of PediatricSurgeryDeborah Loeff, MDBoard of Governors, American College of SurgeonsIllinois State Medical Society, Committee onEconomicsAmerica’s Top Pediatric Surgeons, Castle ConnollyMedical Ltd.Grace Mak, MDMember, American Pediatric Surgical AssociationFellow, American College of SurgeonsPlastic and ReconstructiveSurgeryLawrence J. Gottlieb, MD2011 Physician Recognition Award, Illinois Societyof Plastic SurgeonsWorld Society of Reconstructive Microsurgery-By-Laws Committee, ASRM Council Member; SeniorMember at Large, Education Committee ChairmanEditorial board, The Journal of Reconstructive Microsurgery,Plastic Surgery InternationalEthics Fellowship, MacLean Center for ClinicalMedical Ethics, The University of ChicagoSenior Examiner, American Board of Plastic SurgeryGinard I. Henry, MDAmerican Society for Surgery of the Hand—ResidentEducation Committee, Young Leaders Committee,Website Development Committee, InternationalRelations CommitteeExtremity Surgery Assistant Editor, Plastic SurgeryEducation Network (ASPS website)Review Board, Journal of Hand SurgeryJournal Review Board, Annals of Plastic Surgery14 The University of Chicago Department of Surgery2011 Annual Report 15

Department of Surgery by the numbersRaphael C. Lee, MD, ScD, DSc(hon)America’s Top Doctors, America’s Top PlasticSurgeons, U.S.News & World ReportAmerica’s Top Doctors, Castle Connolly Medical Ltd.America’s Top Surgeons, Consumers’ ResearchCouncil of AmericaTreasurer, Midwestern Society of Plastic SurgeonsPresident-Elect, American Institute for Medical andBiological EngineeringPresident, Drexel 100 SocietyBoard of Directors, Drexel UniversityBoard of Directors, Biomedical Engineering SocietyAdvisory Board for the EBICS, NSF EngineeringResearch CentersTechnology and Health Economics SymposiumChair, American Association for the Advancement ofScience Annual ConferenceInvited Symposia Chair, American Heart Association,Resuscitation Science SocietyRussell R. Reid, MD, PhDCo-Chairman, Association for Osteosynthesis/Association for the Study of Internal Fixation’s BasicPrinciples in Craniomaxillofacial FixationDavid H. Song, MD, MBAScientific Program Chair, American Society ofReconstructive MicrosurgeonsCourse Director, First Annual Chicago BreastReconstruction SymposiumResearchJoel Collier, PhDLong-Range Planning Committee, Society forBiomaterialsKathleen Goss, PhDOutstanding Faculty Presentation in ClinicalResearch, Huggins Research Symposium, TheUniversity of Chicago Department of SurgeryTransplantationYolanda Becker, MDAmerica’s Top Surgeons, Consumers’ ResearchCouncil of AmericaBest Doctors in AmericaAnita S. Chong, PhDRoche Organ Transplantation Research Foundation(ROTRF) Recognition PrizeJohn Renz, MD, PhDInvited Moderator, Invited Speaker, AmericanTransplant CongressInvited Participant, U.S. Department of Health andHuman Services, Health Resources and Services,Administration Organ Donation Task ForceInvited Speaker, National Association of TransplantCoordinators Annual MeetingNational Ultrasound Faculty, American College ofSurgeonsMedical Advisory Committee, American LiverFoundationAdvisory Council, Gift of Hope Organ and TissueDonor NetworkPiotr Witkowski, MD, PhDBasic Science Mentor Award, Transplantation Societyand The American Society of Transplantation at XIITTS Basic Science Symposium/II ESOT BasicScience Symposium, Cape Cod, MAInvestigator Travel Award, The International Isletand Pancreas Transplantation Association Congress,PragueScientific Award, 18th Annual Charles B. HugginsResearch Symposium, The University of ChicagoDepartment of SurgeryUrologyGregory Bales, MDTop Doctors for Women (Urology), Chicago magazineScott Eggener, MDReviewer of the Year, Journal of UrologyMohan S. Gundeti, MDHumanitarianism Award (towards the citizens ofHaiti), The University of ChicagoHonorable Mention for Take Home Messages, WorldCongress of Endourology, Chicago, ILBest Doctors in AmericaArieh L. Shalhav, MDPresident, 28th World Congress of EndourologyMeeting, Chicago, IllinoisNorm Smith, MDSelected for American Urological Association’sLeadership ProgramVascular Surgery &Endovascular TherapyChristopher L. Skelly, MDAssociate Examiner, American Board of SurgeryAssociate Scientific Advisor, Science TranslationalMedicineHapak Entrepreneurship SeminarElected Membership, The Society of UniversitySurgeonsClinical ActivityCases Visits RVUsCardiac and Thoracic Surgery 1,157 3,231 57,996General Surgery 2,689 13,770 69,353Neurosurgery 990 4,479 31,542Ophthalmology and Visual Science 311 10,364 45,167Orthopaedic Surgery and Rehabilitation Medicine 2,797 22,241 88,749Otolaryngology-Head and Neck Surgery 2,031 17,354 48,258Pediatric Surgery 1,123 2,149 22,842Plastic and Reconstructive Surgery 1,197 6,416 42,167Transplantation 525 1,991 20,014Urology 2,089 9,235 65,671Vascular Surgery and Endovascular Therapy 419 1,956 20,360Research Activity96 Active GrantsOver 600 Peer-Reviewed Publications$9 million Federal Funding$11.3 million Total Grant FundingEducational ActivityResidentsFellowsGeneral Surgery 54 Cardiac and Thoracic Surgery 1Neurosurgery 10 General Surgery - Colon and Rectal Surgery 1Ophthalmology and Visual Science 9 General Surgery - Endocrine Surgery 1Orthopaedic Surgery and Rehabilitation Medicine 20 General Surgery - Surgical Oncology 6Otolaryngology-Head and Neck Surgery 9 Neurosurgery 1Plastic and Reconstructive Surgery 6 Ophthalmology and Visual Science - Vitreoretinal Surgery 2Urology 12 Orthopaedic Surgery and Rehabilitation Medicine 7Pediatric Surgery 2Plastic and Reconstructive Surgery 1Transplantation 2Urology 3Vascular Surgery and Endovascular Therapy 2Total Residents 120 Total Fellows 2916 The University of Chicago Department of Surgery2011 Annual Report 17

DevelopmentSection ReportsWe would like to extend our gratitude to all of the Department’s supporters. Because of the generosity of thiscommunity of donors and volunteers, we continue to accomplish our priorities and realize our aspirations.These partnerships are integral to meaningful progress and intricately connected to many of the highlightsshared throughout this annual report.Philanthropic support enhances patient care, research and educationacross the Department, facilitating endeavors such as innovative surgicaltechniques, laboratory research into new therapies, minimally invasiveand robotic surgery, as well as fellowships and named professorships.Visionary donors to the New Hospital Pavilion, designed for optimalpatient-centered care in the 21st century, are helping advance this premierfacility that answers today’s surgical requirements while providing theflexibility to adapt to tomorrow’s techniques and equipment.Opportunities for involvement abound throughout the Department.Upcoming events include Discovery & Impact programs, privatelyhosteddinners and lectures. For more information about philanthropicgiving, inspiring events taking place this year or other ways you canmake a difference, please contact:Stephanie DahlCampaign DirectorUniversity of Chicago Medical Centersdahl@mcdmail.uchicago.edu(773) 834-4726http://supportucmc.uchicago.eduMajor donors to the Department for Fiscal Year 2011 include:• Mr. and Mrs. Joel Barnett• Alvin H. Baum Family Fund• John Benfield• The Brinson Foundation• Mr. Charles E. Compton• Gary and Jodi Cullen• James and Bettina Faulkner• The Foley Family Foundation• Goldman Sachs & Co.• Deanna Hodges• Patricia Ismail• Mr. and Mrs. Mark Kaufman• Courtney A. Kleman Trust• Kovler Family Foundation• Estate of Harold Laufman, MD, PhD• Robert Lopp• Mr. James P. McHugh• John and Marlane Paleczny• Michael Rolfe Pancreatic Cancer Foundation• Mr. and Mrs. Charles Rivkin• Mr. and Mrs. Theodore Roberts• Drs. Rostik and Joan Zajtchuk• Michael and Diane Tang• Mr. and Mrs. Richard Tinberg• Mr. E. Herbert Tinney• Dr. and Mrs. James Williams• Zaccone Family FoundationP a t i e n tEducationA key element of “Chicago Style Surgery” is patient education. During a consultation, a surgeon will take asmuch time as necessary to answer all of the patient’s questions to explain as clearly as possible the patient’scondition, options, prognosis and recovery. Many times, the surgeon will end up sketching a diagram of whatwill happen during the planned surgical procedure to help the patient visualize the surgery.In keeping with the theme of “Chicago Style Surgery,” each section report this year features a surgeon’s drawingof a typical procedure performed by that Section.Valluvan Jeevanandam, MD, Jeffrey B. Matthews, MD, and Trustee Jim Frank enjoy conversationArieh L. Shalhav, MD, speaks to the audience about his workas a pioneer in minimally invasive urologic cancer surgery18 The University of Chicago Department of Surgery2011 Annual Report 19

Cardiac and Thoracic SurgeryThe Section of Cardiac and Thoracic Surgery draws upon atradition of innovative clinical practice and scientific researchto provide the highest level of patient care. The clinical facultyprovides treatment to the most complex patients, with particularspecialization in heart and lung transplants, ventricularassist device implants, complex reconstruction, minimallyinvasive valvular and arrhythmia surgeries, malignancies,esophageal diseases as well as high-risk pulmonary resection.The Section embodies the “Chicago Style Surgery” basicsby ensuring our patients are educated each step of the wayfrom the initial conversation to follow-up care. In addition, thephysician-scientists within the Section pursue a wide rangeof projects, including bench, translational and outcomesresearch focused on cardiac and thoracic diseases.20 The University of Chicago Department of SurgerySection Highlights and AccomplishmentsMahesh P. Gupta, PhD, has received funding for a second R01 grant tostudy the “Activation of Sirtuins to Prevent Adverse Cardiac Remodeling.”Mahesh P. Gupta, PhD, is senior author in a manuscript to be publishedin Science Magazine entitled “Regulation of Akt-signaling by SIRT1.”Gerhard Ziemer, MD, PhD, officially joined the Section in April2011. He is a world-renowned Pediatric Cardiac Surgeon and memberof the World Society for Pediatric and Congenital Heart Surgery.In one of his first two cases at the University of Chicago Medical Center,Gerhard Ziemer, MD, PhD, performed the Norwood procedure; thiscomplex operation defines a comprehensive surgical program.In collaboration with Cardiology, the Section’s Heart Failureprogram is one of the top five implanting programs in the country forVentricular Assist Devices.Since his start in September 2010, Mark Russo, MD, MSc, hasauthored eight articles and has presented these papers at numerousnational meetings.Shahab A. Akhter, MD, was awarded an R01 grant for “Inhibitionof GRK2 to Prevent Ventricular Remodeling and Heart FailureAfter CABG.”Received Joint Commission recertification for our VAD program.Enrolled in the Cardiothoracic Surgical Trials Network (CTSN),a network that enables research teams led by cardiac surgeons toevaluate newer therapies and techniques as they move from laboratoryscience to broad clinical use.Wickii T. Vigneswaran, MD, and Mark K. Ferguson, MD, are nowperforming robotic surgery procedures such as pulmonary lobectomies,segmentectomy and medistinal procedures including thymectomy.Valluvan Jeevanandam, MD, has been approved to enroll patientsin the Heartware REVIVE-IT trial which will compare whethernon-transplant eligible patients with heart failure less advanced thanthat of current LVAD recipients do better with implanted devices thanwith current medical therapy.Under the direction of Mark K. Ferguson, MD, the Section enrolledits first ACGME-accredited Thoracic Residency trainee SampurnaTuladhar, MD.Wickii T. Vigneswaran, MD, was awarded an honorary professorshipat the Universidad Ricardo Palma in Lima, Peru.Faculty ListingValluvan Jeevanandam, MDSection ChiefProfessor of SurgeryProfessors of SurgeryMark K. Ferguson, MDValluvan Jeevanandam, MDWickii T. Vigneswaran, MDGerhard Ziemer, MD, PhD#Associate Professors of SurgeryMahesh P. Gupta, PhDShahab A. Akhter, MDAssistant Professor of SurgeryMark Russo, MD, MScResearch Associate(Assistant Professor of Surgery)Ricky Malhotra, PhD# denotes new facultyRevived the University of Chicago Aortic Specialty Team (UCAST)and have renamed it The University of Chicago Center for AorticDiseases (UCCAD) to be more inclusive of the Section of VascularSurgery and Endovascular Therapy as well as Cardiology. UCCADwill continue to offer referring physicians and outside hospitals24/7 access to a multidisciplinary team of specialists able to assist incomplex aortic emergencies.Established the University of Chicago Medical Center Cardioand Pulmonary Support (CAPS) Interdisciplinary team with theEmergency Department, Cardiology, Pulmonary and the Universityof Chicago Aeromedical Network (UCAN) to offer a miniaturizedportable extracorporeal membrane oxygenation (ECMO) option tothe very sick patient population.2011 Annual Report 21

NeurosurgeryThe Section of Neurosurgery at the University of Chicago hasa rich history that combines research, education and clinicalinnovation to provide excellence in patient care. Over the lastyear, the Section has added a new faculty member, a fellowshiptrained,pediatric neurosurgeon who joined in June 2011. Theexpertise of the clinical faculty encompasses the entirespectrum of clinical neurosurgery. The neurosurgery residencyprogram includes five men and seven women who are pursuinggraduate training in neurosurgery. The Section’s five nursepractitioners and six nurse associates care for patients inboth inpatient and outpatient settings. The faculty physicianscontinue to expand their clinical practice locations to betterserve the patients’ needs.24 The University of Chicago Department of SurgeryAll of the neurosurgeons combine subspecialty clinical expertiseand advanced technology to provide the most effective andup-to-date treatments for the most complex of neurosurgicalproblems. The Section is committed to providing each patientwith individualized, well developed and interdisciplinary optionsfor care through the “Chicago Style Surgery” approach. Fromevery first encounter and onward, the faculty focus on educatingpatients about available treatments and on working togetherto construct a plan that best fits the specific needs of eachindividual. The Section’s clinical expertise goes beyond deliveringthe best in medical care as research activities remain an integralpart of the mission. As the Section continues to engage intranslating investigative work into bedside care, the work toadvance treatment paradigms in each of the neurosurgicalspecialties continues to grow. These subspecialties include:neurovascular surgery, neuro-oncology, surgical epilepsy,spinal surgery, pediatric and congenital neurosurgery, andfunctional/stereotactic neurosurgery.Section Highlights and AccomplishmentsRanked #29 among Neurosurgery/Neurology programs by U.S.News& World Report (July 2011) and #31 for Pediatric Neurosurgery/Neurology programs.Sandi Lam, MD, joined the Section in June 2011 as an AssistantProfessor of Surgery. She is a fellowship-trained pediatric neurosurgeonwith surgical interests that include epilepsy, hydrocephalus, brain andspinal tumors, vascular anomalies, craniosynostosis and craniocervicalanomalies. Dr. Lam is currently working on collaborative outcomesresearch in neurosurgery. She has an interest in providing medicalcare to understand overseas populations and has traveled to Kenya toprovide neurosurgical care.Bakhtiar Yamini, MD, has a newly funded NIH/NCI projectentitled: “Nanoparticles and Nanocapsules for Glioma Targeting.”Maciej S. Lesniak, MD, has two upcoming NIH-funded researchprojects including: Magnetic Vortex Nanodiscs for Glioma Therapyand Nanobio Photocatalyst for Targeted Brain Cancer Therapy. Formore information about Dr. Lesniak’s groundbreaking research inbrain cancer, please visit www.lesniaklab.com.The Neurovascular Surgery Laboratory continues its NIH/NINDSfundedresearch on the biology of cerebrovascular malformations.Issam A. Awad, MD, MSc, MA (hon), and colleagues describedthe first reliable model of cerebral cavernous malformations in mice,based on heterozygous state and double hits, mimicking humanlesions (Human Molecular Genetics, 2011). Based on previous reportsFaculty ListingDavid M. Frim, MD, PhDSection ChiefProfessor of SurgeryProfessors of SurgeryIssam A. Awad, MD, MSc, MA (hon)David M. Frim, MD, PhDJavad Hekmat-Panah, MDMaciej S. Lesniak, MDV. Leo Towle, MD*Jeffrey Frank, MD*Gregory Christoforidis, MD*Associate Professors of SurgeryFrederick Brown, MDBen Z. Roitberg, MDPeter Warnke, MDSaeid Mojtahedi, MD*Maureen Lacy, PhD*Assistant Professors of SurgeryPatrik Gabikian, MDBakhtiar Yamini, MDSandi Lam, MD#Leila Khorasani, MDM. Kelly Nicholas, MD, PhD*Fernando Goldenberg, MD*by the same group on ROCK activation in relation to the cavernousmalformation genes, Dr. Awad and colleagues used their new modelto demonstrate the first evidence of therapeutic effect in vivo in thisdisease, using ROCK inhibitors (Stroke, in press, 2011).The Hemorrhagic Stroke Trials Surgical Center in the Section ofNeurosurgery continues to oversee surgical performance in two largeNIH/NINDS multi-institutional trials for intracerebral hemorrhage(MISTIE) and intraventricular hemorrhage (CLEAR). Novelparadigms of surgical procedure optimization have been developed inPhase II studies, leading to enhanced surgical performance in PhaseIII trials, with ongoing telementoring and telemonitoring by the TrialsSurgical Center.Co-principal investigators David M. Frim, MD, PhD, andMaureen Lacy, PhD, have received grants to study therapeuticcognitive interventions in children with Hydrocephalus and ChiariMalformation type 1.Ben Z. Roitberg, MD, was named the Editor-in-Chief of NeurologicalResearch in February 2011. He was also named the Neurological SurgeryResidency Program Director in September 2011.The fourth annual Discover Camp for children with ChiariMalformation, Spina Bifida and other neurosystem congenitalanomalies was held in late July. The camp is sponsored by pediatricneurosurgeon David M. Frim, MD, PhD, who works with many ofthese families, as an opportunity to enjoy summertime activities in asafe and supportive environment.Leila Khorasani, MD, has established a pediatric neurosurgicalElmhurst Clinic, which expands the Section’s practice locations toElmhurst, Evanston and two locations in the City of Chicago.The Section of Neurosurgery is hosting quarterly educationalsymposiums through the Heinrich Kluver Memorial LectureshipEndowment. In the past year, the Section has hosted internationallyrenowned speakers and held events covering: practical advancesin hemorrhagic stroke, the future of stereotactic and functionalneurosurgery, and the diagnosis and treatment of malignant gliomas.Affiliated Clinical FacultyLeonard Kranzler, MD,Clinical Professor of SurgeryResearch Associates(Assistant Professors of Surgery)Irina Balyasnikova, PhDCatherine Ojakangas, PhDRobert Shenkar, PhDChangbin Shi, MD, PhDIlya Ulosov, DVM, PhDPostdoctoral ScholarsClayton Crawley, PhDPragati Nigam, PhDMelanie Prasol, PhDDerek Wainwright, PhD* denotes secondary appointment# denotes new faculty2011 Annual Report 25

Ophthalmology and Visual ScienceThe Section of Ophthalmology and Visual Science provides Dr. Hariprasad directs a two-year fellowship program incomprehensive medical and surgical treatment of eye vitreoretinal surgery, which accepts one new trainee per year.diseases. Offered services include: cataract surgery with Dr. Ksiazek and Michael Saidel, MD, provide the bulk of thelens implantation, corneal transplantation, laser and surgical resident cataract experience, the core of their surgical training.treatment for glaucoma, advanced vitreoretinal procedures, Faculty based at NorthShore University HealthSystem, ledlaser and injection treatment for diabetic retinopathy and agerelatedmacular degeneration, eyelid and orbital oculoplastic resident education.by Marian Macsai, MD, also make major contributions tosurgery, eye muscle surgery for strabismus in children andThe Section of Ophthalmology and Visual Science is fullyadults, and neuro-ophthalmologic diagnostic services.committed to the practice of “Chicago Style Surgery,” providingThe Section leads the way in cutting-edge treatment of not only the most advanced care, but the patient educationretinopathy of prematurity (ROP), spearheaded by Interim that is essential to optimal decision-making and satisfaction.Section Chief Mark Greenwald, MD, with the assistance ofretina specialists Seenu M. Hariprasad, MD, and Michael Blair,MD. Recent therapeutic advances have significantly improvedthe outlook for vision in infants afflicted with this potentiallyblinding condition. Dr. Hariprasad also performs state-of-theartsurgery for a wide range of retinal disorders in adults.Faculty members are strongly committed to education at alllevels. Susan Ksiazek, MD, oversees the teaching of Pritzkermedical students, all of whom receive instruction in diagnosisof eye disease from Section faculty and residents, and of theresidents (three per year) throughout their specialty training.Section Highlights and AccomplishmentsRima McLeod, MD, received funding from the NIH for two R01grants, two U01 grants and an SBIR grant. The goals of her researchare to better understand toxoplasmosis and its pathogenesis, and todevelop better treatment regimens and vaccines.Susan Ksiazek, MD, was promoted to Associate Professor of Surgery.Seenu M. Hariprasad, MD, was named one of 135 LeadingOphthalmologists in America and was listed as a Top Doctor byU.S.News & World Report.Faculty ListingMark Greenwald, MDInterim Section ChiefProfessor of SurgeryProfessors of SurgeryJ. Terry Ernest, MDMark Greenwald, MDRima McLeod, MDSteven K. Shevell, PhD*Associate Professors of SurgerySeenu M. Hariprasad, MDSusan Ksiazek, MDLouise Sclafani, ODAssistant Professor of SurgeryMichael Saidel, MDLouise Sclafani, OD, was an invited speaker for the VanderbiltUniversity Department of Ophthalmology, and was cited or quoted inseveral articles in trade and lay health-related publications.Michael Blair, MD, Jennifer Galvin, MD, and Laura Sanders,MD, joined the Section in 2011.Graduating senior residents Ajay Singh, MD, and Gioconda Mojica,MD, matched with top choice subspecialty fellowship programs inretina and cornea, respectively.Clinical Associates of SurgeryChris Albanis, MDAnupama Anchala, MDMichael Blair, MD#Jennifer Galvin, MD#James Green, MDRama Jager, MDValerie Kattouff, ODJeffrey Nichols, MDA. Gwendolyn Noble, MD, PhDThomas Patrianakos, DOLaura Sanders, MD#* denotes secondary appointment# denotes new faculty26 The University of Chicago Department of Surgery2011 Annual Report 27

Orthopaedic Surgery And Rehabilitation MedicineThe Section of Orthopaedic Surgery and Rehabilitation Medicinedistinguishes itself in patient care, research and education.Following the “Chicago Style Surgery” philosophy, the facultyprovide comprehensive and compassionate care to patients.The Section has expertise in a wide range of subspecialtiesincluding: foot and ankle, hand and upper extremity, joint/reconstruction, orthopaedic oncology, pediatric orthopaedicsurgery, spine, sports medicine and rehabilitation medicine.Complementing the clinical practice are the expanded residentand fellowship programs and the active clinical and basicscience efforts. The Section is committed to growing the bodyof medical knowledge and creating a lasting contribution inthe field of orthopaedic surgery.Section Highlights and AccomplishmentsJovito Angeles, MD, joined the Section in March 2011. He specializesin hand and upper extremity surgery with particular interestin biomechanics of the hand, bone stabilization devices and nerveregeneration. Dr. Angeles is an American Academy for Cerebral Palsyand Developmental Medicine Fellow and member of the InternationalSociety for Brachial Plexus and Peripheral Nerve Injury.Robert Bielski, MD, is an examiner for the American Board ofOrthopaedic Surgery and a reviewer for the Journal of Bone and JointSurgery. Dr. Bielski was an invited lecturer at the 2011 Midwest PodiatryConference in Chicago and faculty contributor at the 18th AnnualPrimary Care Orthopaedics Conference.Roderick Birnie, MD, continues his busy clinical practice in handand upper extremity surgery. He was a faculty contributor for the 18thAnnual Primary Care Orthopaedics Conference and is President ofthe Chicago Society for Surgery of the Hand.Henry Finn, MD, continues in his role as the Medical Director for theWeiss Memorial Hospital Chicago Center for Orthopedics, which hecreated with the Weiss administration. Dr. Finn was the recipient of the2010 Wilkes University Health Sciences Distinguished Service Award.28 The University of Chicago Department of SurgeryPurnendu Gupta, MD, continues to be active in the Scoliosis ResearchSociety. He is an Editor for The Spine Journal, the American Journal ofSports Medicine, the Archives of Physical Medicine and Rehabilitation,Clinical Biomechanics and Clinical Orthopaedics and Related Research.Dr. Gupta continues in his role as Director of the University of ChicagoSpine Center at Weiss Memorial Hospital.Rex C. Haydon, MD, PhD, received the 2011 Gerald R. LarosTeaching Award. He was named Program Director for the Universityof Chicago Orthopaedic Oncology Fellowship program. Dr. Haydonwas the keynote speaker at the University of Chicago Pritzker Schoolof Medicine White Coat Ceremony and presented at the 18th AnnualPrimary Care Orthopaedics Conference. Dr. Haydon is a monthlylecturer at Loyola University’s Department of Orthopaedic Surgery,Co-Instructor for the Musculoskeletal Clinicopathologic Seminar andCourse Director for the Orthopaedic Basic Science Curriculum.Tong-Chuan He, MD, PhD, continues research on cancer, stemcells and bone biology. He collaborates with other faculty in the areasof tendon and ligament repair, articular cartilage regeneration andimplant wear-induced osteolysis and spine. Dr. He is a member of theCommittee on Molecular Medicine, the Committee on Cancer Biology,the Committee on Genetics and the Committee on Cell Physiology atthe University of Chicago. He is an Adjunct Professor at ChongqingUniversity’s School of Bioengineering in China and member of theInternational Chinese Hard Tissue Society.Sherwin Ho, MD, is President of the Illinois Association of OrthopaedicSurgeons. He successfully directed the 18th Annual PrimaryCare Orthopaedics Conference and continues his role as ProgramDirector for the University of Chicago Sports Medicine Fellowship.J. Martin Leland III, MD, achieved Board Certification in OrthopaedicSurgery. He is a member of the American Orthopaedic Societyfor Sports Medicine Self-Assessment Committee and Principal Reviewerfor The American Journal of Sports Medicine. Dr. Leland servesas Co-Director for the University of Chicago’s 18th Annual PrimaryCare Orthopaedics Conference. He is actively involved with the Universityof Chicago Summer Research Mentor program for medicalstudents and the Department’s “Integrated OR” Committee for theNew Hospital Pavilion. He continues to work with Concordia Collegeand numerous local high schools.Hue Luu, MD, continues to review grants for the American CancerSociety, Orthopaedic Research and Education Foundation and theLiddy Shriver Foundation. He completed his Orthopaedic ResearchSociety/American Academy of Orthopaedic Surgeons’ Career DevelopmentTraveling Fellowship. Dr. Luu’s research focus is on Insulin-Like Growth Factor Binding Protein 5 (IGFBP5). He published a seniorauthor paper in Oncogene on the role of IGFBP5 in osteosarcoma.David Manning, MD, was promoted to Associate Professor of Surgery.He was faculty at the “Back to Basics: Hip and Knee” course, co-sponsoredby the International Congress for Joint Reconstruction and the Mid-America Orthopedic Association (MAOA). Dr. Manning is a reviewerfor the Journal of Bone and Joint Surgery. He completed a scientificinvestigation of the Early Walk Program for minimally invasive kneereplacement. This resulted in presentations at the American Academyof Orthopaedic Surgeons and MAOA. Dr. Manning is Director of theThird Year Medical Students Orthopaedic Surgery Rotation, Directorof the Fourth Year Medical Student Surgery Sub-Internship and managesresident recruitment for Orthopaedic Surgery.John Martell, MD, is Director of the Orthopaedic Biomedical ImagingInstitute at Weiss Memorial Hospital. He is Principal Investigatorfor the Harris Foundation’s Mid-term Longevity Study: A MulticenterStudy for Wear Analysis of Longevity in Total Hip Arthroplasty. Dr.Martell collaborates with the Academic Network for ConservationalHip Outcomes Research and Argonne National Laboratory. He wasnominated for the American Orthopaedic Association’s DistinguishedContributions to Orthopaedics Award. He is an Abstract Reviewer forthe Orthopaedic Research Society’s Section of Arthroplasty and theJournal of Wear.Daniel P. Mass, MD, completed editing a book on tendon repairs.Dr. Mass and Dr. Hussein Turki volunteered in Lima, Peru throughthe auspices of Health Volunteers Overseas. He successfully chairedFaculty ListingMichael A. Simon, MDInterim Section ChiefProfessor of SurgeryProfessors of SurgeryHenry Finn, MDDaniel P. Mass, MDAnthony Montag, MD*Terrance D. Peabody, MDMichael A. Simon, MDBrian Toolan, MDProfessor Emeritus of SurgeryBruce Reider, MDAssociate Professors of SurgeryPurnendu Gupta, MDTong-Chuan He, MD, PhDSherwin Ho, MDJohn Martell, MDRex C. Haydon, MD, PhDDavid Manning, MDAssistant Professors of SurgeryJovito Angeles, MD#Holly Benjamin, MD*Robert Bielski, MDRoderick Birnie, MDJ. Martin Leland III, MDHue Luu, MDChristopher Sullivan, MDClinical Associate Professors of SurgeryMichelle Gittler, MDSung-Lana Kim, MDEdward Park, MDSuzan Rayner, MDClinical Assistant Professors of SurgeryMary Lawler, MDGayle Spill, MDLisa Thornton, MD“Doctors Demystify Shoulders” for OTs and PTs and conducted thefreshman Anatomy Lecture and Anatomy Dissection Lab for the WinterQuarter. He also began a multi-site study on total wrist arthroplasties.Terrance D. Peabody, MD, was named the First President-Elect ofthe American Orthopaedic Association. He was Visiting Professor atthe University of California, Irvine, the University of Maryland andYale University Department of Orthopaedic Surgery. He was also theSeymour Orlov Visiting Professor in Oncology at Loyola University.Bruce Reider, MD, is the Editor-in-Chief of the American Journal ofSports Medicine. He serves on the Medical Publishing Board of Trusteesand the Board of Directors for the American Orthopaedic Societyfor Sports Medicine. Dr. Reider leads the University of ChicagoOrthopaedic Journal Club. He presented at the European Federationof National Sports Trauma Societies and at the American OrthopaedicSociety for Sports Medicine Annual Meeting.Michael A. Simon, MD, serves as the Associate Dean of GraduateMedical Education and Designated Institutional Officer for theUniversity of Chicago Medical Center. He provides historical perspectiveand mentors faculty and residents. He is Treasurer of OMeGA, a nonprofitLLC for distributing industry-supported educational grants.Christopher Sullivan, MD, continues his busy pediatric practice.Dr. Sullivan is a reviewer for Clinical Orthopaedics and Related Research.He was the recipient of the Family Defense Center’s 2010 FamilyDefender Award.Brian Toolan, MD, is an American Board of Orthopaedic SurgeryExaminer for the Part II (Oral boards) and Maintenance of Certification.Dr. Toolan continues his role as Program Director for the OrthopaedicSurgery Residency, which had a successful internal program review.Dr. Toolan presented an Instructional Course Lecture at the 78thAnnual Meeting of the American Academy of Orthopaedic Surgeons.Postdoctoral ScholarsXiang (Sean) Chen, MD, PhDKe (Candy) Yang, MD, PhDJian-Li (Jenny) Gao, PhDPostdoctoral FellowsHong Liu, MD, PhDJing Cui, MDNing Hu, MDRuidong Li, MDWenwen Zhang, MDJiye (Andy) Zhang, MDYuhan Kong, MDLinyuan (Cecilia) Wang, MDJinhua Wang, MDPhD/MD StudentsEnyi HuangStephanie Kim* denotes secondary appointment# denotes new faculty2011 Annual Report 29

Plastic and Reconstructive SurgerySurgeons in the Section of Plastic and Reconstructive Surgeryprovide compassionate and superior healthcare, advanceplastic surgery through research and innovation, as well astrain the future leaders of plastic surgery in a collegial setting.The Section provides a broad range of surgical services topeople suffering from the compromising effects of injury ordisease as well as those wishing to modify a certain physicalfeature. This includes the field of complex microsurgicalreconstruction of the head/neck, extremity and breast.“Chicago Style Surgery” was launched in the Section of PlasticSurgery. Each surgeon is committed to helping patients gaingreater insight into their surgical care by encouraging them toask questions, sharing diagrams and illustrations, and providinga thorough explanation of terminology, all with the purpose ofhelping each patient understand their condition and options.Healing begins with greater understanding and patients becomepartners in their care.As Midwest leaders in reconstructive microsurgery, theSection offers one of the top Plastic Surgery residency trainingprograms in the country and a prestigious one-year fellowshipin complex microsurgical reconstruction. This, coupledwith internationally recognized faculty and the addition ofa partnership with NorthShore University HealthSystem’sDivision of Plastic Surgery, has placed The University of ChicagoSection of Plastic and Reconstructive Surgery as a premierprogram known for innovation, education and clinical excellence.Section Highlights and AccomplishmentsLawrence J. Gottlieb, MD, is the recipient of the 2011 Illinois Societyof Plastic Surgeons’ (ISPS) Physician Recognition Award, which ispresented annually to the ISPS member who has demonstrated a lifelongcommitment and dedication to teaching residents and students.He was a Senior Examiner at the American Board of Plastic Surgery.He was elected to the By-Laws Committee for the World Society ofReconstructive Microsurgery. Dr. Gottlieb completed the Ethics Fellowshipat the University of Chicago MacLean Center for ClinicalMedical Ethics. He is on the Editorial Board for The Journal of ReconstructiveMicrosurgery and Plastic Surgery International. Dr. Gottliebwas a Visiting Professor at Dartmouth as well as Hadassah Hospitalin Jerusalem, Israel. Dr. Gottlieb was a panel Chairman on GenitalReconstruction at the World Society for Reconstructive Microsurgerymeeting in Helsinki, Finland.Ginard I. Henry, MD, and Lawrence S. Zachary, MD, conductedtwo patient educational events for the Scleroderma Foundation discussingRaynaud’s Syndrome and the Cold Hand Clinic, blood flowand Botox injections.Ginard I. Henry, MD is an Assistant Editor on the American Societyof Plastic Surgery’s Plastic Surgery Education Network website.Raphael C. Lee, MD, ScD, DSc (hon), was elected President ofthe Drexel 100 Society and is on the Board of Directors for DrexelUniversity. He is on the Board of Directors for the BiomedicalEngineering Society and the Advisory Board for the National ScienceFoundation’s Engineering Research Center, EBICS. He is a major userof the NIH Shared Instrument Grant: Beagle Supercomputer. He waselected President-Elect for the American Institute for Medical andBiological Engineering.Julie E. Park, MD, was Co-Director for the first Annual Chicago BreastReconstruction Symposium. She presented Breast Conservation Therapyat the Symposium. She is currently conducting a needs assessment studyon sexual dysfunction in women presenting for breast reconstruction.Russell R. Reid, MD, PhD, started a new clinic, The CraniofacialAnomalies Multidisciplinary Program (C.A.M.P.) that includescraniofacial surgery, genetics and neurosurgery. The purpose of theclinic is to provide consolidated, comprehensive care to patients withcomplex, syndromic and nonsyndromic craniofacial issues who, upuntil now, have received scattered care. He is the Co-Chairman of theAssociation for Osteosynthesis/Association for the Study of InternalFixation’s Basic Principles in Craniomaxillofacial Fixation. He was alecturer on cleft lip palate at the Advances in Pediatrics 2011 Symposiumheld at Advocate Lutheran General Hospital. He was the SessionCo-Chair of Craniofacial Research for the European Plastic SurgeryFaculty ListingDavid H. Song, MD, MBASection ChiefProfessor and Vice-Chairman of SurgeryProfessors of SurgeryLawrence J. Gottlieb, MDRaphael C. Lee, MD, ScD, DSc (hon)David H. Song, MD, MBAAssociate Professors of SurgeryLawrence S. Zachary, MDRussell R. Reid, MD, PhDAssistant Professors of SurgeryGinard I. Henry, MDJulie E. Park, MDResearch Council in Hamburg, Germany. Dr. Reid was also theSession Co-Chair of Research in Plastic Surgery at the 2010 AmericanSociety of Plastic Surgeons meeting in Toronto.David H. Song, MD, MBA, was elected the Scientific Program Chairfor the American Society of Reconstructive Microsurgeons. He wasthe Course Director for the first Annual Chicago Breast ReconstructionSymposium. Dr. Song is also the Trunk and Lower Extremity VolumeEditor of the definitive textbook, Plastic Surgery (Third Edition).Lawrence S. Zachary, MD, was appointed Director of the PlasticSurgery Foundation Clinical Fellowship in Post-Bariatric BodyContouring. He received a Clinical Fellowship Grant for Post-BariatricContouring from the Plastic Surgery Foundation. He is on the WeissMemorial Hospital Surgical and Infection Control Committees.Clinical Associates of SurgeryGary Burget, MDLaurie Casas, MDJulius Few, MDPeter Geldner, MDMichael Howard, MDLoren Schechter, MDMark Sisco, MDDavid Teplica, MD, MFAJeremy Warner, MD34 The University of Chicago Department of Surgery2011 Annual Report 35

TransplantationThe Section of Transplantation has surgeons with vast expertisein the areas of kidney, liver and pancreas transplantation, aswell as complex surgical procedures involving multi-organtransplants, hepatobiliary and vascular access surgery. TheUniversity of Chicago Medical Center is among the select fewin the nation that is actively studying the effectiveness of islettransplantation to treat advanced Type 1 diabetes.The Section of Transplantation continued to advance as oneof the first clinics to implement an electronic medical recordssystem in an outpatient setting in addition to consolidatingteams into one location to create an ideal, patient-centricexperience. The Section continues to incorporate new technologiesand efficiencies to improve patient safety and providequality, individualized care for all of patients. Consistent withthe practice of “Chicago Style Surgery,” the Section also takesany necessary steps to ensure patients feel educated abouttheir options for transplantation.Section Highlights and AccomplishmentsHosted three transplant surgeons from Peking Union Medical CollegeHospital, a prestigious medical institution in China, as part of theongoing collaboration between the University of Chicago and Chinato better understand the model of patient management and to furtherdevelop the practice and policy of transplantation in China.Yolanda Becker, MD, and J. Richard Thistlethwaite, Jr., MD,PhD, performed the first six-way SWAP on March 4, 2011.In May 2011, after 19.5 hours on the operating table, one of theSection’s patients became the 10th person in the United States andthe fourth at the University of Chicago Medical Center to have asuccessful heart, liver, and kidney transplant. Valluvan Jeevanandam,MD, transplanted the heart, John Renz, MD, PhD, transplanted theliver, and Yolanda Becker, MD, transplanted the kidney. This wasthe first-ever liver and kidney transplant performed on an intra-aorticballoon pump. The success of this multi-organ operation was a resultof the seamless integration of transplant surgeons, physicians, ORnurses, OR support staff and the anesthesia team.Received full, unconditional re-accreditation from the Centers ofMedicare and Medicaid Services for all solid organ programs after thesite survey in the fall of 2010.Piotr Witkowski, MD, PhD, presented “Coating of HumanPancreatic Islets with CD4+CD25highCD127- T Regulatory Cells –A Novel Immunosuppressive Approach” at the 131st annual meetingof the American Surgical Association in Boca Raton, Florida.Anita S. Chong, PhD, received NIH funding in collaboration withJoel Collier, PhD, for “Synthetic protein and peptide assembliesas novel adjuvants and vaccines” and is collaborating on two otherNIH-funded projects. She was also Co-chair of the Basic ScienceCommittee of the Transplantation Society, Co-chair of the BasicScience Program Committee of the 2012 International Congressof the Transplantation Society, and a standing member of the NIHStudy Section, Transplantation, Tolerance and Tumor Immunity. Shealso holds three of her own NIH awards.Faculty ListingJ. Michael Millis, MDSection ChiefProfessor of SurgeryDirector, The University ofChicago Transplant CenterProfessors of SurgeryYolanda Becker, MDAnita S. Chong, PhDJ. Michael Millis, MDJohn Renz, MD, PhDJ. Richard Thistlethwaite, Jr., MD, PhDAssistant Professor of SurgeryPiotr Witkowski, MD, PhDClinical Associate of SurgeryJames Williams, MDResearch Associate(Assistant Professor of Surgery)Roger Sciammas, PhD36 The University of Chicago Department of Surgery2011 Annual Report 37

UrologyThe Section of Urology at the University of Chicago offerspremiere care through a comprehensive program known as“Chicago Style Surgery,” in which great emphasis is placedon empowering patients to make the best educated decisionsabout their surgical care and treatment. A complete portfoliois offered to each patient that includes reference materialsabout the medical center, upcoming appointments, urologicanatomical drawings for teaching, a sheet to record questionsin preparation for their consultation and reference articles ontheir diagnosis. The surgeons go to great lengths to put thepatients at ease and educate them about their diagnosis fromconsultation through the decision of whether or not to havesurgery. We utilize a multidisciplinary approach, including:medical and radiation oncology, radiology, pathology, stomatherapy, sexual function rehabilitation and psychology.Additionally, the multidisciplinary team runs multiple clinicaltrials for the management of high risk and advancedurologic cancers.The surgeons in the Section treat more patients with urologiccancer (prostate, bladder and kidney cancer) than any otherinstitution in Illinois. As one of the leading urologic cancerinstitutions in the country, the Section offers the mostexperienced minimally invasive laparoscopic and roboticcancer surgery program. The most recent milestone occurredin September 2011 with completion of the 3,000th robotic andlaparoscopic surgical case.The team of urologic cancer surgeons at the University ofChicago includes: Scott Eggener, MD, Arieh Shalhav, MD,Gregory Zagaja, MD, Gary D. Steinberg, MD, and Norm Smith,MD. The Section of Urology at the University of Chicago hasfour programs of distinction with nationally and internationallyacclaimed leaders in their fields. These programs are: urologiccancer; adult robotic and laparoscopic surgery; pediatricrobotic surgery (Mohan S. Gundeti, MD, and Dennis Liu, MD);and reconstructive and female urology (Gregory Bales, MD).The basic science laboratories continue to pioneer researchinvolving the scientific mechanisms of cancer metastasis aswell as the molecular events involved in bladder cancer formationand progression, and stem cell research to the scope ofurologic research.Section Highlights and AccomplishmentsRanked among the top 33 Urology programs in the country byU.S.News and World Report (July 2011).Mohan S. Gundeti, MD, will direct the upcoming pediatric roboticcourse, “Pediatric Robotic Urology – Update and Live Case Demonstration”in conjunction with Arieh Shalhav, MD, Gregory Zagaja,MD, and Dennis Liu, MD. This is the second time the course will beoffered for pediatric robotic surgery. Additionally, Dr. Gundetidirected the initial course “The Fundamentals & Advances in PediatricRobotic Urology” at the annual meeting of the American UrologicalAssociation in Washington, DC in May 2011.Gregory Zagaja, MD, directed and organized a national annualcourse for Board review in Urology.Norm Smith, MD, was chosen for the American Urological AssociationLeadership Program’s Class of 2010-2011.Dennis Liu, MD, was named co-director of the UrologyResidency Program.Scott Eggener, MD, and Oto Aytekin, MD, completed the clinicaltrial involving MRI-guided laser ablation of prostate cancer and initiatedthis treatment for all patients in November 2011.Gary D. Steinberg, MD, is the principal investigator of the TengionInc. Phase 1 open label single center exploratory study of an autologousstem cell derived neo-urinary conduit in subjects requiring incontinenturinary diversion following radical cystectomy. This is thefirst human trial of its kind worldwide and he performed the first twohuman cases.Gary D. Steinberg, MD, is the principal investigator for the NationalCancer Institute Cancer Genome Atlas Project for bladder cancer atThe University of Chicago. The University is one of six sites in theUnited States participating in this high priority study.Gary D. Steinberg, MD, is the Conference Director for the courseentitled “Update and Challenging Cases in Urologic Oncology” scheduledto be held at the Gleacher Center in Chicago on October 29, 2011.The Urologic Oncology and Minimally Invasive Surgery Programcontinues to train three clinical fellows and one research fellow per year.Gary D. Steinberg, MD, heads the Uro-Oncology Clinical ResearchFellowship Program. He is one of the world’s leaders in the treatmentof bladder cancer. He is the Chairman of the Scientific AdvisoryBoard of the Bladder Cancer Research Network and Think Tank.Faculty ListingArieh L. Shalhav, MDSection ChiefProfessor of SurgeryDirector of Minimally Invasive UrologyProfessors of SurgeryArieh L. Shalhav, MDWalter Stadler, MD*Gary D. Steinberg, MDCarrie Rinker-Schaeffer, PhDAssociate Professors of SurgeryGregory Bales, MDKate Feinstein, MD*Glenn Gerber, MDAytekin Oto, MD*Norm Smith, MDGregory Zagaja, MDArieh L. Shalhav, MD, is one of the world leaders in laparoscopic androbotic surgery. He presented multiple times this past year on stateof-the-arttreatment of kidney and prostate cancer, most recently inChina at Xin Hua Hospital/Jiao Tung University School of Medicinein Shanghai, China.Expanded the pediatric urology service and outreach to the Westernand Northern suburbs. The Section partners with Edward Hospital,Mt. Sinai, Rush University, and NorthShore University HealthSystemin Evanston, IL.Carrie Rinker-Schaeffer, PhD, is the Vice President of the MetastasisResearch Society. She received an award from the Marsha RivkinCenter for Ovarian Cancer Research for her innovative studies oncancer cell metastasis.Donald J. Vander Griend, PhD, has been awarded funding for hisresearch on stem cells and prostate cancer from The Brinson Foundationand the joint University of Chicago/Northwestern University ProstateCancer Specialized Program of Research Excellence (SPORE).Donald J. Vander Griend, PhD, was a scientific reviewer on theEndocrinology (END) peer review panel for the Prostate CancerResearch Program (PCRP) for the Department of Defense’s (DOD)Congressionally Directed Medical Research Programs (CDMRP).Assistant Professors of SurgeryScott Eggener, MDMohan S. Gundeti, MDDennis Liu, MD#Gladell Paner, MD*Donald J. Vander Griend, PhDClinical Associates of SurgeryDoreen Chung, MD*William Lin, MD*Stephen Nold, MD*Postdoctoral ScholarShay Golan, MD* denotes secondary appointment# denotes new faculty38 The University of Chicago Department of Surgery2011 Annual Report 39

Section Highlights and AccomplishmentsDarwin Eton, MD, joined the Section as a Professor of Surgery inDecember 2010. His clinical practice is weighted to the most complexvascular reconstructions in the chest, abdomen, pelvis and extremities.He performs all open surgical and minimally invasive catheter-basedvascular procedures. He is currently making clinical advances inangiogenesis to promote biological revascularization in patients withcritical limb threatening ischemia.Matthew J. Blecha, MD, joined the Section as a Clinical Associateof Surgery in August 2010. Dr. Blecha has clinical expertise inthe care of peripheral vascular disease, including: lower extremityarterial disease, carotid artery occlusive disease, varicose veins andlower extremity venous insufficiency, aortic and peripheral arteryaneurysms, deep vein thrombosis, renal artery and mesenteric arteryocclusive disease, dialysis access and wound care.Vascular Surgery and Endovascular TherapyThe Section of Vascular Surgery and Endovascular Therapy The Section created the University of Chicago Vascularis undergoing a tremendous transformation. The Department Institute at Weiss Memorial Hospital. The faculty includesof Surgery named Christopher L. Skelly, MD, as Section Chief Heather Hall, MD, Darwin Eton, MD, and Daniel Katz, MD.following the departure of Hisham Bassiouny, MD. Dr. Skelly The Institute offers traditional, open surgery, endovascularhas been on the faculty at the University of Chicago since treatment options and an ICAVL-accredited, non-invasive2005. He currently holds an NIH K08 award to study vascular vascular laboratory. As part of the Institute, the Universitybiology, physiology and gene therapy as applied to neointimal of Chicago Vein Center offers state-of-the-art, noninvasivetesting and innovative treatment plans, includinghyperplasia. He has made seminal contributions to the fieldreflected in high impact publications such as the Proceedings microphlebectomy, vein injection sclerotherapy, vein strippingof the National Academy of Sciences, the Journal of Vascular ligation and VNUS closure (radiofrequency ablation).Surgery, Gene Therapy and the Journal of Surgical Research.The Vascular Surgery Fellowship Program remains vibrant.The short-term strategy of the Section is to rebuild with a Current fellows include Samantha Minc, MD, and Michaellong-term goal of developing an internationally recognized Shao, MD. In addition to rotations at the University of Chicagoacademic program. To supplement these goals, the Section Medical Center and Weiss Memorial Hospital, the fellowssuccessfully recruited a robust group of faculty members, now rotate at NorthShore University HealthSystem with Navincluding: Darwin Eton, MD; Matthew J. Blecha, MD; Heather Gupta, MD; Tina Desai, MD; Nancy Schindler, MD; and JohnHall, MD; and Robert Steppacher, MD.Golan, MD. Plans are underway to develop an integrated 0-5residency in Vascular Surgery and Endovascular Therapy.Complementing the clinical mission, the Section expanded itsresearch efforts with the recruitment of Susan McCormick, All of these efforts will no doubt enhance the patientPhD. Her research focuses on biomechanical forces and their experience. Committed to “Chicago Style Surgery,” the facultyeffects on biological systems, especially at the molecular level. educates patients about their illness or disease and providesShe concentrates on the effects of luminal and interstitial fluid them with all of their options so that they can make the bestshear stress within the vascular system. She has published informed decisions about their surgical treatment and care.seminal work in the Proceedings of the National Academy ofSciences and the American Journal of Physiology. She will beworking with the faculty to create an integrated clinical, basicand translational research program.40 The University of Chicago Department of SurgeryHeather A. Hall, MD, joined the Section as a Clinical Associateof Surgery in August 2011 after finishing her Vascular SurgeryFellowship at the University of Chicago. Dr. Hall has clinicalexpertise in the full range of vascular diseases, including: lowerextremity and upper extremity arterial disease, carotid artery occlusivedisease, aneurysms of the aorta and other arteries, mesenteric ischemiaand renal artery disease. She performs a wide range of vascularprocedures for patients with renal disease, including placement ofdialysis catheters and long-term dialysis access. She has a specialfocus on treatment of venous disease, including: chronic venousinsufficiency, varicose veins, spider veins and venous ulcers. She willbe spearheading the Section’s teaching mission.Robert Steppacher, MD, joined the Section as a Clinical Associateof Surgery in September 2011. Dr. Steppacher’s clinical expertise isin the care of peripheral vascular disease, including: lower extremityarterial disease, diabetic foot ulcers, carotid artery occlusive disease,aortic and peripheral artery aneurysms, renal artery and mesentericartery occlusive disease. He specializes in the treatment of venousdisease including the treatment of varicose veins, chronic venousinsufficiency, venous ulcers, dialysis access and blood clots. He hasa particular interest in outcomes and will be leading the Section’squality initiative.The Non-Invasive Vascular Laboratory, under the direction of LaurieLozanski, RVT, received continued ICAVL accreditation and hasmaintained this since 1994. In the past year, the lab performed almost9,000 studies and has made significant contributions to the financialsuccess of the University of Chicago Medical Center.Faculty ListingChristopher L. Skelly, MDSection ChiefAssistant Professor of SurgeryProfessor of SurgeryDarwin Eton, MD#Assistant Professor of SurgeryChristopher L. Skelly, MDClinical Associates of SurgeryMatthew J. Blecha, MD#Heather A. Hall, MD#Daniel Katz, MD#Robert Steppacher, MD## denotes new facultyExpanded the practice group to include Ani Iskra, APN, who seespatients independently in the clinics and has provided outstandingeducation to students, residents and fellows.Hosted Dr. Michael Conte from the University of California, SanFrancisco as the visiting professor for the Annual Skinner Lecture.Received $100,000 from the family of Harold Laufman, MD, PhD, toestablish the Harold Laufman, MD, PhD, Lectureship and to supportresearch within the Section.Christopher L. Skelly, MD, was named Associate Scientific Advisorfor the journal Science Translational Medicine.2011 Annual Report 41

Current Residents & FellowsResident/Fellow Name PGY YearCardiac and Thoracic SurgeryFellow Sampurna Tuladhar 6General SurgeryResident Julia Berian 1Resident Monika Krezalek 1Resident Joon Jyung Lee 1Resident Susan Lim 1Resident Puneet Singh 1Resident Yalini Vigneswaran 1Resident Mindy Stack 1 PreliminaryResident Jennifer DeFazio 2Resident Lava Patel 2Resident Marko Rojnica 2Resident Baddr Shakhsheer 2Resident Abhineet Uppal 2Resident Sean Wightman 2Resident Reza Salabet 2 PreliminaryResident Melissa Ruiz 2RResident Benjamin Shogan 2RResident Jordan Stern 2RResident Marc Ward 2RResident Erica Carlisle 3Resident Ian Daniel 3Resident Eleanor Drew 3Resident Irma Fleming 3Resident Andrea Olivas 3Resident Jennifer Paruch 3Resident Michelle Cowan 3RResident Megan Miller 3RResident Richelle Williams 3RResident Samuel Kingsley 4Resident Carla Moreira 4Resident Allan Peetz 4Resident Kathleen Romanowski 4Resident Marie Ziesat 4Resident Emily Ahmed 5Resident Trissa Babrowski 5Resident Eric Grossman 5Resident Mark London 5Resident John Seal 5Resident Brian Bello 6Fellow -Colon & Rectal Surgery David Lin 6Fellow -Endocrine Surgery Karen Devon 6Fellow -Surgical Oncology Jennifer Gnerlich 6Fellow -Surgical Oncology Haejin In 6Resident/Fellow Name PGY YearFellow -Surgical Oncology Sabha Ganai 7Fellow -Surgical Oncology Sajid Khan 7Fellow -Surgical Oncology Juan Camilo Barreto Andrade 8Fellow -Surgical Oncology Khaled Hamzeh 8NeurosurgeryResident Ashley Ralston 1Resident Melissa Stamates 1Resident Anita Bhansali 2Resident Javed Khader-Eliyas 2Resident Sophia Shakur 3Resident Mahua Dey 4Resident Nassir Mansour 4Resident Ricky Wong 4Resident Sherise Ferguson 6Resident Ippei Takagi 6Fellow Tanya Filardi 7Ophthalmology and Visual ScienceResident Katherine Chen 2Resident Cheryl Lee 2Resident Patrick Sassani 2Resident Khushboo Agrawal 3Resident Nikhil Batra 3Resident Neha Sangal 3Resident Armin Afshar 4Resident Juner Colina-Biscotto 4Resident Joshua Fernandes 4Fellow -Vitreoretinal Surgery Shaun Ittiara 5Fellow -Vitreoretinal Surgery Ravi Patel 6Orthopaedic Surgery andRehabilitation MedicineResident Joseph Cohen 1Resident Ananth Eleswarapu 1Resident Oliver Schipper 1Resident Jason Somogyi 1Resident Cory Stewart 1Resident Erwin Bennett 2Resident Jimmy Jiang 2Resident Min Lu 2Resident Gautam Malhotra 2Resident Zachary Sisko 2Resident Aneet Toor 2Resident Kevin Hardt 3Resident Tyler Krummenacher 3Resident/Fellow Name PGY YearResident Deepak Reddy 3Resident Christian Skjong 3Resident Kashif Ali 4Resident James Cameron 4Resident Michael Chioffe 4Resident Jay Deimel 4Resident Amrish Patel 4Resident Reginald Alexander 5Resident Mark Bergin 5Resident Kyle Hazelwood 5Resident Thomas O’Hagan 5Resident Noah Shaftel 5Fellow -Adult ReconstructionFellow -Adult ReconstructionFellow - Hand andUpper ExtremityFellow - Hand andUpper ExtremityFellow -Musculoskeletal OncologyYogesh KolwadkarRishi ThakralJacob Bosley 6Yesenia Rodriguez-Alvarez 6Andre Ribeiro de Valle SpiguelFellow - Sports Medicine Benedict Figuerres 6Fellow - Sports Medicine Jovan Laskovski 6Otolaryngology-Head and Neck SurgeryResident Jonathan Lusardi 1Resident Glenda Montague 1Resident Cheryl Nocon 2Resident Ryan Salvador 2Resident Riddhi Patel 3Resident Kristal Wimmer-Kunitomo 3Resident Christian Soneru 4Resident Victoria Varga-Huettner 4Resident Mohamad Chaaban 5Resident Andrea Nath 5Resident Jonathan Sherman 5Pediatric SurgeryFellow Anthony Hogan 6Fellow Shirong Chang 7Plastic And Reconstructive SurgeryResident Maria Artunduaga 1Resident Deana Shenaq 1Resident Daniel Butz 2Resident Essie Kueberuwa 2Resident Lee Alkureishi 3Resident Sam Fuller 3Resident Grant Kleiber 4Resident Jonathan Bank 4Resident Matthew Greives 5Resident Trang Nguyen 5666Resident/Fellow Name PGY YearResident Sara Dickie 6Resident Justine Lee 6Fellow - ReconstructiveBreast/Microsurgery Aaron Pelletier 7TransplantationResident Qi Lee 7Resident Oyedolamu Olaitan 8UrologyResident Blake Anderson 1Resident Joseph Pariser 1Resident Shane Pearce 1Resident David Hatcher 2Resident Rena Malik 2Resident Aria Razmaria 2Resident Joshua Cohn 3Resident Pankaj Dangle 3Resident Cassandra Lall 3Resident Charles Chang 3RResident Olufenwa Famakinwa 3RResident Kyle Kiriluk 4Resident Alexandre Rosen 4Resident Gautam Jayram 5Resident Marcelo Orvieto 5Fellow Michael Large 6Fellow Sandip Prasad 7Fellow Amit Patel 8Vascular Surgery andEndovascular TherapyFellow Samantha Minc 6Fellow Michael Shao 742 The University of Chicago Department of Surgery2011 Annual Report 43

2011 GraduatesFaculty Publications 2010–2011Resident/Fellow Name PGY Year Position After Leaving UC ProgramGeneral SurgeryResident Vidas Dumasius Graduate Plastic Surgery Fellowship, University of Minnesota, MinneapolisResident Christopher Kenney Graduate Transplant Fellowship, University of Wisconsin, MadisonResident Jason Long Graduate Cardiothoracic Surgery Fellowship, University of Michigan, Ann ArborResident Alizah Rotramel Graduate Colon and Rectal Surgery Fellowship, Penn StateMilton S. Hershey Medical CenterResident Lisa Spiguel Graduate Breast Oncology Fellowship, Northwestern University, Chicago, ILFellow -Colon & Rectal Surgery Aaron Miller Graduate New York, NYFellow -Surgical Oncology Emily Bellavance Graduate Assistant Professor of Surgery, University of Maryland Medical Center,Baltimore, MDNeurosurgeryResident Joseph Hsieh Graduate Spine Fellowship, Cedar Sinai Hospital, Los Angeles, CAOphthalmology and Visual ScienceResident Gioconda Mojica Graduate Cornea Fellowship, University of Minnesota, MinneapolisResident Rominder Momi Graduate Dearborn, MIResident Ajay Singh Graduate Fellowship in Retina and Vitreous Diseases,University of Kentucky, LexingtonFellow Paulpoj Chiranand Graduate Associate Physician, Retina Group Chicago, Hinsdale, ILOrthopaedic Surgery and Rehabilitation MedicineResident Michael Angeline Graduate Sports Medicine and Shoulder Fellowship, Hospital for Special Surgery,New York, NYResident Waqas Hussain Graduate Sports Medicine Fellowship, Cleveland Clinic, OHResident Andre Ribeiro do Valle Spiguel Graduate Musculoskeletal Oncology Fellowship, The University of ChicagoResident Robert Steffner Graduate Trauma Fellowship, University of California, DavisFellow -Adult Reconstruction Sarkis Bedikian Graduate Weiss Memorial Hospital, Chicago, IllinoisFellow -Adult Reconstruction Suresh Patil Graduate Fellowship, NebraskaFellow - Hand andUpper ExtremityHussein Turki Graduate Attending Physician, Alabama Orthopaedic Specialists, Montgomery, ALFellow -Musculoskeletal Oncology Tessa Balach Graduate Attending Physician, University of Connecticut, Farmington, CTFellow -Sports Medicine Alexander Meininger Graduate Attending Physician, Moab Regional Hospital, Moab, UtahOtolaryngology-Head and Neck SurgeryResident David Brown Graduate Private Practice, Bethlehem ENT Associates, Bethlehem, PAPlastic and Reconstructive SurgeryResident Aaron Pelletier Graduate Reconstructive Breast/Microsurgery Fellowship, The University of ChicagoResident Michelle Roughton Graduate Joined Dr. Loren Schechter's Practice, Morton Grove, ILFellow - Microsurgery Daniel Kwan Graduate Sanford Clinic Surgical Associates, Sioux Falls, SDTransplantationFellow Reynold Lopez-Soler Graduate Sentara Virginia Beach General Hospital Transplant Center,Virginia Beach, VAUrologyResident Michael Large Graduate Fellowship, The University of ChicagoResident Mark Wille Graduate Faculty, John H. Stroger Jr. Hospital of Cook County, Chicago, ILFellow Guarionex DeCastro Graduate Faculty, Columbia University, New York, NYFellow Gagan Gautam Graduate Sr. Consultant & Head of Uro-Oncology & Robotic Surgery,Medanta - The Medicity, IndiaFellow Sergey Shikanov Graduate Faculty, University of New Mexico, Albuquerque, NMVascular Surgery and Endovascular TherapyCardiac & Thoracic SurgeryShahab A. Akhter, MDAkhter SA, Raman J, Jeevanandam V. Technique forLeft Ventricular Apical Cannulation for Short-TermMechanical Circulatory Support. Ann Thor Surg2010; 89(3):994–995Rajan S, Jagatheesan G, Karam CN, Alves ML, BodiI, Schwartz A, Bulcao C, D’Souza KM, Akhter SA,Boivin GP, Dube DK, Petrashevskaya N, Herr AB,Hullin R, Liggett SB, Wolska BM, Solaro RJ,Wieczorek DF. Molecular and Functional Characterizationof a Novel Cardiac-Specific Human TropomyosinIsoform. Circulation 2010; 121(3):410–418Bulcao CF, D’Souza KM, Malhotra R, Staron M,Duffy JY, Pandalai PK, Jeevanandam V, Akhter SA.Activation of JAK-STAT and Nitric Oxide Signalingas a Mechanism for Donor Heart Dysfunction. JHeart Lung Transplant 2010; 29(3):346–351Lin EP, Boire A, Hemmige V, Husain AN, Sorrentino M,Nathan S, Akhter SA, Dickstein J, Archer SL. CardiacTamponade as an Initial Presentation of ChronicLymphocytic Leukemia: Similarities to TuberculousPericarditis. J Med Case Reports 2010; 4:426Malhotra R, D’Souza KM, Staron ML, Birukov KG,Bodi I, Akhter SA. G alpha(q)-Mediated Activationof GRK2 by Mechanical Stretch in Cardiac Myocytes;The Role of Protein Kinase C. J Biol Chem 2010;285(18):13748–13760Akhter SA, D’Souza KM, Malhotra R, Staron ML,Valeroso TB, Fedson SE, Anderson AS, Raman J,Jeevanandam V. Reversal of Impaired MyocardialBeta-Adrenergic Receptor Signaling by Continuous-Flow Left Ventricular Assist Device Support. 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Golgi protein 73 (GOLPH2) is avaluable serum marker for hepatocellular carcinoma.Gut 2010; Dec; 59(12):1687–93Stock PG, BarinB, Murphy B, hanto D, Diego JM,Light J, Davis C, Blumberg E, Simon D, SubramanianA, Millis JM, Lyon GM, Brayman K, SlakeyD, Shapiro R, Melancon J, Jacobson JM, Stosor V,Olson JL, Stablein DM, Roland ME. Outcomes ofkidney transplantation in HIV-infected recipients. NEngl J Med 2010; Nov 18;363 (21):1004–14.McDiarmid SV, Ravinder A, Martz K, Millis JM,Masariegos G. The SPLIT Research Group. A multivirateanalysis of pre, peri, and post transplant factorseffecting outcome after pediatric liver transplantation.Annals of Surgery 2010Agarwal S, Dorafshar AH, Harland RC, Millis JM,Gottlieb LJ. Liver and vascularized posterior rectussheath fascia composite tissue allotransplantation. AmJ Transplant 2010Kizilel S, Scavone A, Liu X, Nothias JM, Ostrega D,Witkowski P, Millis JM. Encapsulation of pancreaticislets within nano-thin functional peg coatings forenhanced insulin secretion. Tissue Eng Part A 2010Liu XY, Nothias JM, Scavone A, Garfinkel M, MillisJM. Biocompatibility investigation of polyethyleneglycol and alginate-poly-l-pysine for islet encapsulation.ASAIO J 2010; May–Jun; 56(3):241–5Grossman EJ, Millis JM. Liver transplantationfor non-hepatocellular carcinoma malignancy:Indications, limitations, and analysis of the currentliterature. Liver Transpl 2010; 16(8):930–42Millis JM. Small-for size donor syndrome? LiverTranspl 2011; 17(4):355–6Marek N, Krzystyniak A, Ergenc I, Cochet O,Misawa R, Wang LJ, Golab K, Wang X, KilimnikG, Hara M, Kiizilel S, Trzonkowski R, Millis JM,Witkowski P. Coating Human Pancreatic Islets WithCD4+CD4highCD127-Regulatory T Cells as aNovel Approach for the Local Imunoprotection. AnnSurg 2011; 254(3):512–9Huan J, Millis JM, Mao Y, Millis MA, Zhong S, SangX. China’s Pilot Program of Organ Donation froPatients Following Cardiac Death. The Lancet 2011;In PressJohn Renz, MD, PhDKaplan B, Jie T, Diana R, Renz J, Whinery A, StubbsN, Bracamonte E, Spier C. Histopathology and immunophenotypeof the spleen during acute antibodymediated rejection. American Journal of Transplantation2010; 10(5):1316–1320Renz JF. A critical analysis of liver allograft utilizationfrom the US deceased donor pool. Liver Transplantation2010; 16(5):543–547Guarrera JV, Henry SD, Odeh-Ramadan R, ChenSWC, Kinkhabwala M, Goldstein MJ, Ratner LE,Renz JF, Lee HT, Brown RS Jr., Emond JC.Hypothermic machine preservation in human livertransplantation: the first clinical series. AmericanJournal of Transplantation 2010; 10(2):372–381Roger Sciammas, PhDSciammas R, Li Y, Warmflash A, Song Y, DinnerAR, Singh H. An incoherent regulatory networkarchitecture that orchestrates B cell diversificationin response to antigen signaling. Mol Syst Biol. 2011May 24;7:495J. Richard Thistlethwaite, Jr., MD, PhDChon WJ, Kadambi PV, Harland RC, ThistlethwaiteJR, West BL, Udani S, Poduval R, Josephson MA.Changing Attitudes Toward Influenza Vaccinationin U.S. Kidney Transplant Programs Over the PastDecade. Clin J Am Soc Nephrol 2010Hippen BE, Thistlethwaite JR Jr, Ross LF. Risk, prognosis,and unintended consequences in kidney allocation.N Engl J Med 2011 Apr 7; 364(14):1285–7James Williams, MDLivingston S, Deubner H, Bruden D, McMahon B,Homan C, Townshend-Bulson L, Bruce M, HennessyT, Williams J, Gretch D. Factors associated withthe progression of fibrosis on liver biopsy in AlaskaNative and American Indian persons with chronichepatitis C. Can J Gastroenterol 2010; 24(7):445–51Piotr Witkowski, MD, PhDHardy MA, Witkowski P, Sondermeijer H, HarrisP. The long road to pancreatic islet transplantation.World J Surg 2010; 34(4):625–7Kizilel S, Scavone A, Liu X, Nothias JM, Ostrega D,Witkowski P, Millis JM. Encapsulation of pancreaticislets within nano-thin functional polyethylene glycolcoatings for enhanced insulin secretion. Tissue EngPart A 2010; 16(7):2217–28Chang CC, Vlad G, D’Agati VD, Liu Z, Zhang QY,Witkowski P, Torkamani AA, Stokes MB, Ho EK,Cortesini R, Suciu-Foca N. BCL6 Is Required forDifferentiation of Ig-Like Transcript 3-Fc-InducedCD8+ T Suppressor Cells. J Immunol 2010Marek N, Krzystyniak A, Ergenc I, Cochet O,Misawa R, Wang LJ, K Golab, Liu XJ, Kizilel S,Trzonkowski P, Matthews JB, Michael Millis JM,Witkowski P. Coating of Human Pancreatic Isletswith CD4+CD25highCD127- T Regulatory Cells—a Novel Immunosuppressive Approach. Ann Surg2011; 254(3):512–9Marek N, Bieniaszewska M, Krzystyniak A,Juscinska J, Mysliwska J, Witkowsk P, HellmannA, Trzonkowski P. The time is crucial for ex-vivoexpansion of T regulatory cells for the therapy. CellTransplantation 2011Kim A, Kilimnik G, Guo C, Sung J, Jo J, Periwal V,Witkowski P, Dilorio P, Hara M. Computer-assistedLarge-scale Visualization and Quantification of PancreaticIslet Mass, Size Distribution and Architecture.J Vis Exp 2011; 49:2471UrologyGregory Bales, MDKennelly MJ, McCammon KA, Knoll LD, JonesLA, Bales GT, Herschorn S, Roberts B, Boone TB,Webster GD. Two-Year Follow-up Results in a Multi-Center, Prospective Trial of the Advance Male SlingSystem for the Treatment of Post-Prostatectomy StressUrinary Incontinence. Journal of Urology 2010Bales GT, Reynolds WS, Kit LC, Kaufman MR,Karram K, Dmochowski RR. Obturator ForamenDissection for Excision of Symptomatic TransobturatorMesh. Journal of Urology 2011Scott Eggener, MDGautam G, Lifshitz D, Shikanov S, Moore JM,Eggener SE, Shalhav AL, Chang A. Histopathologicalpredictors of renal function decrease after laparoscopicradical nephrectomy. Journal of Urology 2010;184(5):1872–6Shikanov S, Clark MA, Raman JD, Smith B, Kaag M,Russo P, Wheat JC, Wolf JS, Huang WC, Shalhav AL,Eggener SE. Chronic Kidney Disease EpidemiologyCollaboration Versus Modification of Diet in RenalDisease Equations for Renal Function Evaluation inPatients Undergoing Partial Nephrectomy. J Urol 2010Jayram G, Szmulewitz RZ, Eggener SE. Managementof good-risk metastatic nonseminomatous germ celltumors of the testis: Current concepts and controversies.Indian J Urol 2010; 26(1):92–7Clark MA, Shikanov S, Raman JD, Smith B, KaagM, Russo P, Wheat JC, Wolf JS, Matin SF, HuangWC, Shalhav AL, Eggener SE. Chronic KidneyDisease Before and After Partial Nephrectomy. Journalof Urology 2011; 185(1):43–8Messer J, Shariat SF, Brien JC, Herman MP, Ng CK,Scherr DS, Scoll B, Uzzo RG, Wille M, Eggener SE,Steinberg G, Terrell JD, Lucas SM, Lotan Y, BoorjianSA, Raman JD. Urinary Cytology has a poorperformance for predicting invasive or high-gradeupper-tract urothelial carcinoma. BJU Int 2011;108(5):701–5Eggener SE, Scardino PT, Walsh PC, Han M, PartinAW, Trock BJ, Feng Z, Wood DP, Eastham JA, YossepowitchO, Rabah DM, Kattan MW, Yu C, KleinEA, Stephenson AJ. Predicting Fifteen-Year ProstateCancer-Specific Mortality Following Radical Prostatectomy.Journal of Urology 2011; 185(3):869–75Katz MH, Shikanov S, Sun M, Abdollah F, BudaeusL, Gong EM, Eggener SE, Steinberg GD, Zagaja GP,Shalhav AL, Karakiewicz PI, Zorn KC. Gleason 6prostate cancer in one or two biopsy cores can harbormore aggressive disease. Journal of Endourology 2011;25(4):699–703Drazer M, Huo D, Schonberg M, Eggener SE.Population-Based Patterns and Predictors of PSAScreening Among Older Men in the United States.Journal of Clinical Oncology 2011; 29(13):1736–43Rosen A, Jayram G, Drazer M, Eggener SE. GlobalTrends in Testicular Cancer Incidence and Mortality.European Urology 2011; 60(2):374–9Glenn Gerber, MDRazmaria AA, Lifshitz DA, Gofrit ON, Shikanov S,Shalhav AL, Gerber G, Bhojani N, Zorn KC. Drillingthrough impacted ureteral stones: use of the atherectomyrotablator device for urolithiasis. J Endourol2010; 24(7):1141–4Mohan S. Gundeti, MDMarchetti P, Razmaria A, Zagaja GP, Gundeti MS.Management of the Ventriculo-Peritoneal Shunt inPediatric Patients during Robotic-Assisted LaparoscopicUrological Procedures. Epub 2010Gundeti MS, Wiltz AL, Zagaja GP, Shalhav AL.Robot-Assisted Laparoscopic Intracorporeal Hand-Sewn Bowel Anastomosis During Pediatric BladderReconstructive Surgery. J Endourol 2010Wille M, Zagaja G, Shalhav A, Gundeti MS.Continence Outcomes in Patients UndergoingRobotic-Assisted Laparoscopic Continent CatheterizableChannel Creation. Epub 2011Elassiuty Y, Klarquist J, Yousef R, El Rafaee A,Hunter N, Shaker O, Gundeti MS, Nieuweboer-Krobotova L, Le Poole I. Caroline. Heme Oxygenase-1Expression Protects Melanocytes from Stress-InducedCell Death. Implications for Vitiligo Exp Dermatol 2011Dennis Liu, MDMarks A, Maizels M, Mickelson J, Yerkes E, AnthonyHerndon CD, Lane J, Ben-Ami T, Maizels E, StoltzRS, Dixon S, Liu D, Chaviano T, Hagerty J, KaplanW. Effectiveness of the computer enhanced visuallearning method in teaching the society for fetalurology hydronephrosis grading system for urologytrainees. J Pediatr Urol 2011; 7(2):113–7Carrie Rinker-Schaeffer, PhDShoustari AN, Szmulewitz RZ, Rinker-Schaeffer CW.Metastasis-suppressor genes in clinical practice: lost intranslation? Nat Rev Clin Oncol 2011; 8(6):333–42Szmulewitz RZ, Clark R, Lotan T, Otto K, TaylorVeneris J, Macleod K, Rinker-Schaeffer CW. MKK4suppresses metastatic colonization by multiplehighly metastatic prostate cancer cell lines through atransient impairment in cell cycle progression. Int JCancer. 2011 Feb 23Thiolloy S, Rinker-Schaeffer CW. Thinking outsidethe box: using metastasis suppressors as moleculartools. 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Veneris JT, Bainer R, Yamada SD, Lingen M, GiladY, Rinker-Schaeffer CW. Dissecting Events ControllingMetastatic Colonization. 2011Khan S, Taylor JL, Rinker-Schaeffer CW. Disruptingovarian cancer metastatic colonization: insights frommetastasis suppressor studies. J Oncol 2010Arieh L. Shalhav, MDGofrit ON, Harlev M, Rosenberg S, Pode D, ZornKC, Shalhav AL, Zamir G, Mintz Y. Pure “cable-tiepartial nephrectomy”: a porcine model. SurgicalEndoscopy 2010; 24(12):3229–32Shikanov S, Clark MA, Raman JD, Smith B, Kaag M,Russo P, Wheat JC, Wolf JS, Huang WC, Shalhav AL,Eggener SE. Chronic Kidney Disease EpidemiologyCollaboration Versus Modification of Diet in RenalDisease Equations for Renal Function Evaluation inPatients Undergoing Partial Nephrectomy. J Urol 2010Oto A, Kayhan A, Jiang Y, Tretiakova M, Yang C,Antic T, Dahi F, Shalhav AL, Karczmar G, StadlerWM. Prostate Cancer: Differentiation of CentralGland Cancer from Benign Prostatic Hyperplasia byUsing Diffusion-weighted and Dynamic ContrastenhancedMR Imaging. Radiology 2010Gundeti MS, Wiltz AL, Zagaja GP, Shalhav AL.Robot-assisted laparoscopic intracorporeal hand-sewnbowel anastomosis during pediatric bladder reconstructivesurgery. J Endourol 2010; 24(8):1325–8Razmaria AA, Lifshitz DA, Gofrit ON, Shikanov S,Shalhav AL, Gerber G, Bhojani N, Zorn KC. Drillingthrough impacted ureteral stones: use of the atherectomyrotablator device for urolithiasis. J Endourol2010; 24(7):1141–4Deklaj T, Lifshitz DA, Shikanov SA, Katz MH, ZornKC, Shalhav AL. Laparoscopic radical versus laparoscopicpartial nephrectomy for clinical T1bN0M0renal tumors: comparison of perioperative, pathological,and functional outcomes. Journal of Endourology2010; 24(10):1603–7Zorn KC, Bhojani N, Gautam G, Shikanov S, GofritON, Jayram G, Katz MH, Cagiannos I, Budaus L,Abdollah F, Sun M, Karakiewicz PI, Shalhav AL,Al-Ahmadie HA. Application of ice cold irrigationduring vascular pedicle control of robot-assistedradical prostatectomy: EnSeal instrument cooling toreduce collateral thermal tissue damage. Journal ofEndourology 2010; 24(12):1991–6Gautam G, Lifshitz D, Shikanov S, Moore JM,Eggener SE, Shalhav AL, Chang A. Histopathologicalpredictors of renal function decrease after laparoscopicradical nephrectomy. Journal of Urology 2010;184(5):1872–6Shikanov S, Clark MA, Raman JD, Smith B, KaagM, Russo P, Wheat JC, Wolf JS Jr, Huang WC,Shalhav AL, Eggener SE. Chronic Kidney DiseaseEpidemiology Collaboration versus Modification ofDiet in Renal Disease equations for renal functionevaluation in patients undergoing partial nephrectomy.Journal of Urology 2010; 184(5):1867–71Oto A, Kayhan A, Jiang Y, Tretiakova M, Yang C,Antic T, Dahi F, Shalhav AL, Karczmar G, StadlerWM. Prostate cancer: differentiation of central glandcancer from benign prostatic hyperplasia by usingdiffusion-weighted and dynamic contrast-enhancedMR imaging. Radiology 2010; 257(3):715–23Gundeti MS, Wiltz AL, Zagaja GP, Shalhav AL.Robot-assisted laparoscopic intracorporeal handsewnbowel anastomosis during pediatric bladderreconstructive surgery. Journal of Endourology 2010;24(8):1325–8Razmaria AA, Lifshitz DA, Gofrit ON, ShikanovS, Shalhav AL, Gerber G, Bhojani N, Zorn KC.Drilling through impacted ureteral stones: use of theatherectomy rotablator device for urolithiasis. Journalof Endourology 2010; 24(7):1141–4Song J, Li M, Zagaja GP, Taxy JB, Shalhav AL,Al-Ahmadie HA. Intraoperative frozen sectionassessment of pelvic lymph nodes during radicalprostatectomy is of limited value. BJU International2010; 106(10):1463–7Wille MA, Zagaja GP, Shalhav AL, Gundeti MS.Continence Outcomes in Patients UndergoingRobotic Assisted Laparoscopic Mitrofanoff Appendicovesicostomy.Journal of Urology 2011Jayram G, Decastro GJ, Large MC, Razmaria A,Zagaja GP, Shalhav AL, Brendler CB. Robotic radicalprostatectomy in patients with high-risk disease: areview of short-term outcomes from a high-volumecenter. Journal of Endourology 2011; 25(3):455–7Katz MH, Shikanov S, Sun M, Abdollah F, BudaeusL, Gong EM, Eggener SE, Steinberg GD, ZagajaGP, Shalhav AL, Karakiewicz PI, Zorn KC. Gleason6 Prostate Cancer in One or Two Biopsy Cores CanHarbor More Aggressive Disease. Journal ofEndourology 2011Clark MA, Shikanov S, Raman JD, Smith B, KaagM, Russo P, Wheat JC, Wolf JS Jr, Matin SF, HuangWC, Shalhav AL, Eggener SE. Chronic kidneydisease before and after partial nephrectomy. Journalof Urology 2011; 185(1):43–8Marchetti PE, Shikanov S, Razmaria AA, ZagajaGP, Shalhav AL. Impact of Prostate Weight onProbability of Positive Surgical Margins in PatientsWith Low-risk Prostate Cancer After Robotic-assistedLaparoscopic Radical Prostatectomy. Urology 2011;77(3):677–81Gundeti MS, Acharya SS, Zagaja GP, Shalhav AL.Pediatric robotic-assisted laparoscopic augmentationileocystoplasty and Mitrofanoff appendicovesicostomy(RALIMA): feasibility of and initial experiencewith the University of Chicago technique. BJUInternational 2011; 107(6):962–9Norm D. Smith, MDHelfand BT, Smith ND, Kozlowski JM, EskandariMK. Vena Cava Thrombectomy and Primary Repairafter Radical Nephrectomy for Renal Cell Carcinoma:Single-Center Experience. Ann Vasc Surg 2010Walter M. Stadler, MDOto A, Kayhan A, Jiang Y, Tretiakova M, Yang C,Antic T, Dahi F, Shalhav AL, Karczmar G, StadlerWM. Prostate Cancer: Differentiation of CentralGland Cancer from Benign Prostatic Hyperplasia byUsing Diffusion-weighted and Dynamic ContrastenhancedMR Imaging. Radiology 2010O’Donnell PH, Undevia SD, Stadler WM, KarrisonTM, Nicholas MK, Janisch L, Ratain MJ. A phase Istudy of continuous infusion cilengitide in patientswith solid tumors. Invest New Drugs 2010Kindler HL, Wroblewski K, Wallace JA, Hall MJ,Locker G, Nattam S, Agamah E, Stadler WM, VokesEE. Gemcitabine plus sorafenib in patients withadvanced pancreatic cancer: a phase II trial of theUniversity of Chicago Phase II Consortium. InvestNew Drugs 2010Bukowski RM, Stadler WM, McDermott DF,Dutcher JP, Knox JJ, Miller WH, Hainsworth JD,Henderson CA, Hajdenberg J, Kindwall-Keller TL,Ernstoff MS, Drabkin HA, Curti BD, Chu L, RyanCW, Hotte SJ, Xia C, Cupit L, Figlin RA. Safetyand efficacy of sorafenib in elderly patients treated inthe North American advanced renal cell carcinomasorafenib expanded access program. Oncology 2010;78(5–6):340–7Mohile SG, Lacy M, Rodin M, Bylow K, DaleW, Meager MR, Stadler WM. Cognitive effects ofandrogen deprivation therapy in an older cohort ofmen with prostate cancer. Crit Rev Oncol Hematol2010; 75(2):152–9Twardowski P, Stadler WM, Frankel P, Lara PN,Ruel C, Chatta G, Heath E, Quinn DI, GandaraDR. Phase II Study of Aflibercept (VEGF-Trap) inPatients With Recurrent or Metastatic UrothelialCancer, a California Cancer Consortium Trial.Urology 2010Mohile SG, Lacy M, Rodin M, Bylow K, Dale W,Meager MR, Stadler WM. WITHDRAWN: Cognitiveeffects of androgen deprivation therapy in anolder cohort of men with prostrate cancer. Crit RevOncol Hematol 2010Liauw SL, Stadler WM, Correa D, WeichselbaumRR, Jani AB. Dose-escalated radiotherapy for highriskprostate cancer: outcomes in modern era withshort-term androgen deprivation therapy. Int J RadiatOncol Biol Phys 2010; 77(1):125–30Oto A, Kayhan A, Jiang Y, Tretiakova M, Yang C,Antic T, Dahi F, Shalhav AL, Karczmar G, StadlerWM. Prostate Cancer: Differentiation of CentralGland Cancer from Benign Prostatic Hyperplasia byUsing Diffusion-weighted and Dynamic ContrastenhancedMR Imaging. Radiology 2010O’Donnell PH, Undevia SD, Stadler WM, KarrisonTM, Nicholas MK, Janisch L, Ratain MJ. A phase Istudy of continuous infusion cilengitide in patientswith solid tumors. Invest New Drugs 2010Kindler HL, Wroblewski K, Wallace JA, Hall MJ,Locker G, Nattam S, Agamah E, Stadler WM, VokesEE. Gemcitabine plus sorafenib in patients withadvanced pancreatic cancer: a phase II trial of theUniversity of Chicago Phase II Consortium. InvestNew Drugs 2010Bukowski RM, Stadler WM, McDermott DF,Dutcher JP, Knox JJ, Miller WH, Hainsworth JD,Henderson CA, Hajdenberg J, Kindwall-Keller TL,Ernstoff MS, Drabkin HA, Curti BD, Chu L, RyanCW, Hotte SJ, Xia C, Cupit L, Figlin RA. Safetyand efficacy of sorafenib in elderly patients treated inthe North American advanced renal cell carcinomasorafenib expanded access program. Oncology 2010;78(5–6):340–7Mohile SG, Lacy M, Rodin M, Bylow K, DaleW, Meager MR, Stadler WM. Cognitive effects ofandrogen deprivation therapy in an older cohort ofmen with prostate cancer. Crit Rev Oncol Hematol2010; 75(2):152–9Twardowski P, Stadler WM, Frankel P, Lara PN,Ruel C, Chatta G, Heath E, Quinn DI, GandaraDR. Phase II Study of Aflibercept (VEGF-Trap) inPatients With Recurrent or Metastatic UrothelialCancer, a California Cancer Consortium Trial.Urology 2010Mohile SG, Lacy M, Rodin M, Bylow K, Dale W,Meager MR, Stadler WM. WITHDRAWN: Cognitiveeffects of androgen deprivation therapy in anolder cohort of men with prostrate cancer. Crit RevOncol Hematol 2010Liauw SL, Stadler WM, Correa D, WeichselbaumRR, Jani AB. Dose-escalated radiotherapy for highriskprostate cancer: outcomes in modern era withshort-term androgen deprivation therapy. Int J RadiatOncol Biol Phys 2010; 77(1):125–30Gary D. Steinberg, MDSteinberg GD. Editorial Comment. 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Journal of Endourology 2011;25(4):699–703Willie MA, Zagaja GP, Shalhav AL, Gundeti MS.Continence Outcomes in Patients UndergoingRobotic Assisted Laparoscopic Mitrofanoff Appendicovesicostomy.Journal of Urology 2011Jayram G, Decastro GJ, Large MC, Razmaria A,Zagaja GP, Shalhav AL, Brendler CB. Robotic radicalprostatectomy in patients with high-risk disease: areview of short-term outcomes from a high-volumecenter. Journal of Endourol 2011; 25(3):455–7Vascular Surgery andEndovascular TherapyMichael J. Blecha, MDWillson TD, Revesz E, Podbielski FJ, Blecha MJ.External iliac artery dissection secondary to endofibrosisin a cyclist. J Vasc Surg. 2010 Jul;52(1):219–21Darwin Eton, MDShao H, Xu Q, Wu Q, Ma Q, Salgueiro L, Wang J,Eton D, Webster KA, Yu H. Defective CXCR4Expression in Aged Bone Marrow Cells ImpairsVascular Regeneration. J Cell Mol Med 2010Susan McCormick, PhDSaini V, McCormick SM. 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Sci Transl Med. 17August 2011: 3(96)Skelly CL. Setting sights on a silent killer. Sci TranslMed. 20 July 2011: 3(92)Skelly CL. Home is where the heart is. Sci TranslMed. 22 June 2011: 3(88)Skelly CL. Construction-Deconstruction-Reconstruction.Sci Transl Med. 25 May 2011: 3(84)Skelly CL. Balloons with brains. Sci Transl Med. 27April 2011: 3(80)Skelly CL. PEG gets to the heart of the matter. SciTransl Med. 30 March 2011: 3(76)Skelly CL. These peptides have got a lot of nerve. SciTransl Med. 2 March 2011: 3(72)62 The University of Chicago Department of Surgery2011 Annual Report 63

Buildingt r u s t a n dpartnership“We believe that building trust and partnership with our patients is paramount. We engage in open dialogueand open-ended discussion as part of our clinical mission, just as we do in our research and educationmissions. We take the time to listen to our patients and their families, hear their concerns, answer theirquestions and help them search for answers.”Jeffrey B. Matthews, MDSurgeon-in-Chief and Chair, Department of SurgeryDallas B. Phemister Professor of Surgery64The University of Chicago Department of SurgeryDesign: Words&Pictures, Inc.

Department of Surgery5841 South Maryland Avenue, MC 5029Chicago, IL 60637773.702.0881Web site: http://surgery.uchicago.eduFacebook: http://www.facebook.com/uchicagosurgeryTwitter: http://twitter.com/uchicagosurgery