Indian Journal of Pharmacy Practice Association of Pharmaceutical ...
Indian Journal of Pharmacy Practice Association of Pharmaceutical ...
Indian Journal of Pharmacy Practice Association of Pharmaceutical ...
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Sundara M MN - Treatment <strong>of</strong> Obesity with Sibutramine, Metformin, Acarbose and Lifestyle Modifications: A Cross-Sectional Study<strong>Indian</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmacy</strong> <strong>Practice</strong> Volume 3 Issue 4 Oct - Dec, 2010 46
Sundara M MN - Treatment <strong>of</strong> Obesity with Sibutramine, Metformin, Acarbose and Lifestyle Modifications: A Cross-Sectional StudyFlow Chart <strong>of</strong> Subjects Disposition and Demographic details, who participated and completed the study· 11 subjects withdrawn their consent· 5 subjects did not report for the furtherassessmentAge Distribution· 18-27 years 35.00% (n=42)· 28-37 years 34.17% (n=41)· 38-47 years 22.50% (n=27)· 48-55 years 8.33% (n=10)384 obese subjects were screened248 subjects were excluded136 obese subjects randomised120 obese subjects completed the studyBaseline & Demographic Characteristics· 134 subjects had Diabetes Mellitus· 48 subjects had elevated BP· 12 subjects had very high BMI (>40)· 31 subjects had very low BMI (
Sundara M MN - Treatment <strong>of</strong> Obesity with Sibutramine, Metformin, Acarbose and Lifestyle Modifications: A Cross-Sectional StudyTable 3: Systolic and Diastolic Blood Pressure reduction between visits 1 and 4 among the study groupVariables Sibutramine Metformin Acarbose *LSMParameters(N=31) (N=30) (N=29) (N=30)Systolic Blood Mean 10.00 9.00 6.55 6.00Pressure S.D 8.56 9.22 10.44 9.32(Visit 1 and 4)‘ t ’ value 6.50 5.34 3.37 3.52Diastolic Blood Mean 1.93 1.33 2.06 0.33Pressure S.D 9.45 4.34 4.91 4.13(Visit 1 and 4)‘ t ’ value 1.13 1.68 2.26 0.44*LSM-Life style modifications<strong>Indian</strong> <strong>Journal</strong> <strong>of</strong> <strong>Pharmacy</strong> <strong>Practice</strong> Volume 3 Issue 4 Oct - Dec, 2010 49