Sacks et al., 2009
Sacks et al., 2009
Sacks et al., 2009
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The new england journ<strong>al</strong> of medicineplementary Appendix). Risk factors for cardiovasculardisease and diab<strong>et</strong>es were <strong>al</strong>so an<strong>al</strong>yzedaccording to the intention-to-treat principle, withzero change from baseline imputed for missingdata. The study was powered to d<strong>et</strong>ect a 1.67-kgweight loss as an effect of the level of protein orfat in the di<strong>et</strong> over the 2-year period, assuminga withdraw<strong>al</strong> rate of 40%.Table 1. Baseline Characteristics of the Study Participants.*CharacteristicLow-Fat,Average-Protein Group(N = 204)Low-Fat,High-ProteinGroup(N = 202)High-Fat,Average-Protein Group(N = 204)High-Fat,High-ProteinGroup(N = 201)AllParticipants(N = 811)ParticipantsWhoCompl<strong>et</strong>edthe Study(N = 645)Age — yr 51±9 50±10 52±9 51±9 51±9 52±9Sex — no. (%)Fem<strong>al</strong>e 126 (62) 135 (67) 125 (61) 129 (64) 515 (64) 397 (62)M<strong>al</strong>e 78 (38) 67 (33) 79 (39) 72 (36) 296 (36) 248 (38)Race or <strong>et</strong>hnic group — no. (%)†White 159 (78) 158 (78) 165 (81) 161 (80) 643 (79) 525 (81)Black 33 (16) 33 (16) 28 (14) 33 (16) 127 (16) 88 (14)Asian 1 (
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