Sepsis and Septic Shock in Pregnancy - Children's Memorial ...

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MAP < 50 mmHg?Consider vasopressorsNoMAP 50-65 mmHg orCVP below 8 mmHg?YesNS 500 mLover 30 minutesMAP > 65 mmHg;urine output > 25 mL/hr?NoRepeat bolus until 30 mL/kgNS IV over 3 hoursYesMAP > 65 mmHg?NorepinephrineVasopressinSteroids for refractoryshockNoMAP > 65 mmHg?NoEvaluate need fordeliveryYesObserve need forfurther IV fluidbolusBarton,Sibai2012
Presentation: Temp 103.5, severe flank pain, N and VDiagnosis: PyelonephritisTreatment: IV Fluids, Acetaminophen, IV Antibiotics
Page 1 and 2: Sepsis and Septic Shockin Pregnancy
Page 3 and 4: Cases / 100,000Deaths/YearCompariso
Page 5 and 6: Maternal mortality, 1842“It is no
Page 7 and 8: The Intervention:Hand scrub with ch
Page 9 and 10: Definitions• Sepsis- SIRS due to
Page 11 and 12: Case History• 31 wks, sore throat
Page 13 and 14: Group A StreptococcusThe Etiology,
Page 17 and 18: MicroabscessFascia
Page 19 and 20: Early Goal Directed Therapy• Earl
Page 21 and 22: Mortality (%)The Importance of Earl
Page 23 and 24: Algorithm for Septic Shock in Pregn
Page 25 and 26: Antimicrobial Therapy• Infection
Page 27 and 28: Post-op C/SMultilocularabscessDispl
Page 29 and 30: Postpartumnecrotizingfasciitis
Page 31 and 32: Empiric Antimicrobial Therapy• Ge
Page 33 and 34: Vasoactive Therapy• Indication- H
Page 35: Corticosteroids• Treat patients w
Page 39 and 40: Maintenance PhaseAnticipation of co
Page 41 and 42: H1N1 influenza-associated ARDS: Bil
Page 43 and 44: Indications for surgical interventi
Page 46 and 47: Obesity Trends*Among U.S. AdultsDon
Page 48 and 49: Outcome
Page 50 and 51: References• Mabie WC, Barton JR,
Page 52 and 53: References• Walsh C, Scaife C, Ho
Page 54 and 55: References• Kitter ND, McMullen K
Page 56 and 57: Historical Guidelines for Sepsis Th
Page 58 and 59: Probability of SurvivalFluid Resusc
Page 60 and 61: Drotrecogin Alfa (Xigris)• Decrea
Page 62 and 63: VentricularFunctionGroup INormalGro
Page 64 and 65: Varicella-Zosterin Pregnancy
Page 66: BACKGROUNDGlobal• Puerperal sepsi

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