Inflammations of the nervous system

Purulent meningitisPathogens:•adult: Pnemococcus, N. meningitidis,•child: Hemophylus, EnterobacteriaClinical picture:primary extracranial manifestation (lung,paranasal)severe condition, high fever, prominentmeningeal signs, confusion (high mortality !)residual signs (hydrocephalus, hypacusis,ment. retard., epileptic seizures)CSF: green-like•1000 to several 10,000 cells/ul, granulocytes•high protein level (1-3 g/1)•low sugarDg: microbiol. cultureOther: eradication of the (respiratory) sourceEEG: generalized slowing CT/MRI: look for"pus-cap”, brain abscess, hydrocephalusTherapy: based on the culture. Before:Penicillin + Ampicillin + Ceftriaxon iv., insevere cases + Dexamethason(Steptokinaze)