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(0) 1656 655221 Fax: +44 - Biomet

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FLM201 - 07.09References:1. Robler S, Sewing A, Stolzel M, Born R, Scharnweber S, Dard M, Warch H (2003) Electrochemically assisted deposition of thin calcium phosphate coating at near-physiologicalpH and temperature. J<strong>Biomet</strong> Mater Res 64A:655-6632. Schmidmaier G, Wildemann B, Schwabe P, Stange R, Hoffmann J, Südkamp NP, Haas NP, Raschke M (2002) A new electrochemically graded hydroxyapatite coating forosteosynthetic implants promotes implant osteointegration in a rat model. J Biomed Mater Res 63: 168–172,3. Schliephake H, Scharnweber D, Roesseler S, Dard M, Sewing A, Aref A (2006) Biomimetic calcium phosphate composite coating of dental implants, Int J Oral MaxillofacImplants , 21 (5):738-464. Schliephake H, Scharnweber D, Dard M, Rößler S, Sewing A and Hüttmann C (2003) Biological performance of biomimetic calcium phosphate coating of titanium implants inthe mandible a pilot study in dogs, J Biomed Mat Res 64A: 225-2345. Mont MA, Hungarford DS (1997) Proximally Coated Ingrowth Prosthesis. A Review. Clin Orthop 344: 139-1496. Emerson RH , Sanders SB, Head WC, Higgins L (1999) Effect of circumferential plasma-spray porous coating on the rate of femoral osteolysis after total hip arthroplasty. JBJS81: 1291-12987. Bourne RB, Rorabeck CH, Burkart BC, Kirk P (1994) Ingrowth surfaces: Plasma spray coating to titanium alloy hip replacements. Clin Orthop Relat Res 298: 37-468. Bøe B, Heier T, Snorrason F, Nordsletten L (2006) Change in bone density and implantation AV Taperloc cementless hip prosthetic with two different hydroxyapatite coatings. Aprospective randomized trial. Nordic Orthopaedic Federation 53rd Congress, Oslo, Norway.<strong>Biomet</strong> UK Ltd., as the manufacturer of this device, does not practice medicine and does not recommend any particular surgical technique for useon a specific patient. The surgeon who performs any implant procedure is responsible for determining and utilising the appropriate techniques forimplanting prosthesis in each individual patient.<strong>Biomet</strong> UK Ltd. is not responsible for selection of the appropriate surgical technique, nor does it advocate a particular technique to be utilised onan individual patient.This publication and al the pictures, logos, artwork etc are all the sole property of <strong>Biomet</strong> UK Ltd. Copyright <strong>Biomet</strong> 2009BoneMaster ® is a registered trade mark in Europe of <strong>Biomet</strong> Deutschland GmbH.<strong>Biomet</strong> UK LimitedWaterton Industrial EstateBridgend, South Wales, CF31 3XA,United KingdomTel: <strong>+44</strong> (0) <strong>1656</strong> <strong>655221</strong><strong>Fax</strong>: <strong>+44</strong> (0) <strong>1656</strong> 645454


BoneMaster ®Nano-Crystalline HA Coating TechnologyNano-Crystalline HA CoatingDesign Rationale


<strong>Biomet</strong> UK Ltd., as the manufacturer of this device, does not practice medicine and does not recommend any particular surgical technique for useon a specific patient. The surgeon who performs any implant procedure is responsible for determining and utilising the appropriate techniques forimplanting prosthesis in each individual patient.<strong>Biomet</strong> UK Ltd. is not responsible for selection of the appropriate surgical technique, nor does it advocate a particular technique to be utilised onan individual patient.This publication and al the pictures, logos, artwork etc are all the sole property of <strong>Biomet</strong> UK Ltd. Copyright <strong>Biomet</strong> 2009BoneMaster ® is a registered trade mark in Europe of <strong>Biomet</strong> Deutschland GmbH.


BoneMaster ® – Inspired by NatureBoneMaster ® is an advanced biomimetic coating technology with the biological benefits of hydroxyapatiteand an enhanced needle-like nano-structure based on apatite crystals found in bone. (1)2µmBoneMaster ® coatingBoneBIOMIMETICS: {Derived from the Greek ‘bios’, meaning ‘life’, and ‘mimesis’, meaning ‘toimitate’.}An advanced coating technology, which improves theperformance of cementless implants by mimicking the naturalbone physiology- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


BoneMaster ® is an advanced biomimetic coating technology withthe biological benefits of hydroxyapatite and an enhanced needlelikenano-structure based on apatite crystals found in bone (1) ,offering the following clinical benefits:• Enhanced Implant Stability (2)(2 ; 3)• Reduced Fibrous Ingrowth(3 ; 4)• Increased Bone Density1µm- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


Enhanced Implant StabilityStudies have demonstrated (4) that the unique needle-like topography of BoneMaster ® significantly increasesbone apposition compared to uncoated implants.In essence, the unique needle-like topography of BoneMaster ® , creates a favourable environment forosteoblast adhesion, producing faster bone intergration. The BoneMaster ® coating is ⅟10 of the thickness ofthplasma sprayed HA coating and therefore maintains the topography of the substrate. Hence the 5µm thickBoneMaster ® coating preserves the macro-roughness and porosity of Porous Plasma Spray (PPS TM ) Ti-alloy(5 ; 6 ; 7)coating for enhanced primary and long-term fixation.Uncoated SurfaceBoneMaster ® CoatingFibrous tissueBone tissueTitamium- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


BoneMaster’s ® unique needle-like nano-structure2µm- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


Reduced Fibrous IngrowthThe unique needle-like nano-structure of BoneMaster ® results in it’s excellent osteoconductivity, as a resultof the close resemblance to the apatite found in bone. Through it’s ideal nano-crystalline hydroxyapatitestructure BoneMaster ® promotes faster bone ingrowth and bone apposition resulting in reduced fibrous(2 ; 3)ingrowth.Bone/Implant interface:26% bone tissue coverage without BoneMaster (2) 68% bone tissue coverage with BoneMaster (2)Fibrous tissueBone tissueTitamium- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


Increased Bone Density- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


Increased Bone DensityIn a recent clinical study (8) , BoneMaster ® coated stems showed significantly greater bone density postoperatively, compared to identical plasma-sprayed HA stems.Professor Lars Nordsletten, PhD, MD, has reported results at 12, and 24 months post-operatively showinga greater bone density surrounding the BoneMaster ® coated stems compared with the plasma HA coatedstems; especially in the coated area: Gruen zone 1, where there was a significant increase in bone densitycompared to conventional HA coating.- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -


BoneMaster ® – Inspired by Nature• Enhanced Implant Stability (2)• Reduced Fibrous Ingrowth(2 ; 3)• Increased Bone Density(3 ; 4)- Your attention is drawn to the legal notice and disclaimer in the first and last pages of this publication -

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