University of Pittsburgh Fellowship Program in Infectious Diseases

University of PittsburghFellowship Program inInfectious DiseasesUniversity of PittsburghInfectious DiseasesFellowship ProgramPhone: 648-6406

Mission Statement• The mission of our fellowship program is to trainthe future leaders of infectious diseases inacademic and clinical medicine and research.• We are committed to the mission of providingstate-of-the-art health care that is of the highestquality, compassionate, comprehensive andeasily accessible to patients with a variety ofinfectious diseases.

Mission Statement• We provide excellence in mentoring and trainingfellows, residents, and medical students tobecome leaders in the care of patients withinfectious diseases and leaders in the discoveryof new knowledge in basic, translational, andclinical research.• The Division of Infectious Diseases is wellknownfor its clinical and research excellence in:– HIV/AIDS– Medical mycology– Molecular microbiology and epidemiology– Infection control– Transplant infectious diseases

Statements from the Fellows•“Very strong Fellowship program thatoffers a diverse experience in both clinicaland research training”.•“Well-respected caliber of training. Weappreciate the Division’s commitment toexcellence in teaching and assuring thatwe receive rigorous research training inorder to succeed in academic medicine”.

Statements from the Fellows•“Excellent ID faculty who provide us with abalanced view of clinical infectiousdiseases and bring with them theirparticular research focus or interests toteaching rounds”.•“I’m amazed at the amount of teachingand the concern the fellows get from theattendings. They really want to make surewe succeed in our future plans.”

Outstanding in Teaching• The division of Infectious Diseases hasbeen recognized for its outstandingteaching of the medical students, residentsand fellows, and nominated for variousprestigious teaching awards.

Outstanding in Teaching• Karin Byers, MD– Recipient of the “2008 Clinical Educator of the Year"award presented to faculty who consistently providesoutstanding clinical education in the elective coursesetting for medical students of the University ofPittsburgh School of Medicine.• Peter Veldkamp, MD, MS– Recipient of the “2007 Outstanding TeachingAttending” award from the University of Pittsburgh,Department of Medicine Interns– Recipient of the “2008 Excellence in EducationAward” as Course Director, presented by theDepartment of Medicine Class of 2011.

Outstanding in Teaching• Cornelius J. Clancy, MD– Recipient of “Excellence in Teaching Medical Students” award in2007 while faculty at University of Florida. Dr. Clancy wasrecruited to University of Pittsburgh in November 2007 asDirector of Mycology Research Unit• Minh-Hong Nguyen, MD– Recipient of “Excellence in Teaching Residents and Fellows”and “Excellence in Teaching Medical Students” in 2007 whilefaculty at University of Florida. Dr. Nguyen was recruited toUniversity of Pittsburgh in November 2007 as the Director ofTransplant ID Program and Antibiotic Management Program.– Recipient of the “Thomas Sydenham Distinguished ClinicalTeaching Award” presented by the University of FloridaDepartment of Medicine to the faculty member who bestrepresents the ideals of an outstanding Academic Internist.

Education venues• Weekly ID core curriculum lectures• Weekly journal club• Weekly ID Grand Rounds:– Microbiology photo quiz– Case presentation• Thrice-monthly HIV/AIDS rounds– Antimicrobial resistance– Morbidity and Mortality• Bi-annually Research-in-Progress• Bi-monthly Transplant Infectious Diseasesjournal club (optional)

Outstanding clinical experienceYear 1:• Infectious Diseasesconsultation service: 10months– UPMC General InfectiousDiseases Consult Service– VA Medical Center InfectiousDiseases Consult Service– Surgical Infectious DiseasesConsult Service• Microbiology LaboratoryRotation: 1 month• Infection Control Rotation: 1month• Ambulatory InfectiousDiseases Clinic: 1/2 day perweekYear 2:• Biomedical Research Training:9 months• Transplant Infectious DiseasesConsult Service: 1 month• Surgical Infectious DiseasesConsult Service: 2 weeks• Ambulatory HIV/AIDS Clinic:1/2 day per weekYear 3 (optional):• Biomedical Research Training:11 months• Ambulatory HIV/AIDS Clinic:1/2 day per week

Diversity of Clinical Cases• UPMC at the University of Pittsburgh is a tertiarycare referral hospital with a unique strategy ofcombining clinical and research excellencetranslates into state-of-the-art, evidence-basedpatient care and advances in biotechnology• It is a renowned center in transplantation,cancer, neurosurgery, orthopedic surgery,endocrinology, otolaryngology, rheumatology,gastroenterology, nephrology, pulmonology,geriatric care, cardiology and cardiac surgery,psychiatry, rehabilitation and urology

Diversity of Clinical Cases• The fellows encounter bread and butter casesas well as exotic cases in:– Bacteriology– Mycology–Virology– Parasitology• The fellows also round at the VA Medical Centerwhere they encounter a variety of communityacquiredinfections and infectious complicationsof diabetes mellitus and other chronic medicaldiseases, solid organ cancer andtransplantation.

Diversity of Clinical Cases• Microbiology is a major part of infectiousdiseases training.– The general ID service rounds in theMicrobiology laboratory prior to go to thepatient’s bed side.– A weekly microbiology quiz is an integral partof fellows’ education.

Recent Weekly Micro Quiz“Sailing to South America”“Imported Fever from Afghanistan”“What the eyes don’t see the heartdoesn’t feel – is it always true?”

Outstanding ResearchOpportunities• The Division of Infectious Diseases has anoutstanding track record in training nextgeneration researchers.• Our recent fellows have been recognized atprestigious national meetings for the excellenceof their research, including the InfectiousDiseases Society of America Annual Meetingand the American Society of Microbiology’sInterscience Conference on Antimicrobial Agentsand Chemotherapy.

Outstanding ResearchOpportunities5• 59% of our fellows inthe past decade haveassumed academicpositions at majorteaching institutionsNumber ofFellows4321OthersPrivateAcademic01999 2002 2004 2006 2008Graduating years

Recent Fellows Selected 1 stAuthored Publications• Curry SR, et al. tcdC genotypes associated withsevere TcdC truncation in an epidemic cloneand other strains of Clostridium difficile. J ClinMicrobiol. 2007;45:2103• Doi Y, et al. Coproduction of novel 16S rRNAmethylase RmtD and metallo-beta-lactamaseSPM-1 in a panresistant Pseudomonasaeruginosa isolate from Brazil. AntimicrobAgents Chemother. 2007;51:852-6.• Doi Y, et al. 16S ribosomal RNA methylation:emerging resistance mechanism againstaminoglycosides. Clin Infect Dis. 2007;45:88-94.

Fellows Selected 1 st AuthoredPublications• Doi Y, et al. High prevalence of metallo-betalactamaseand 16S rRNA methylasecoproduction among imipenem-resistantPseudomonas aeruginosa isolates in Brazil.Antimicrob Agents Chemother. 2007;51:3388-90.• Doi Y, et al. Identification of 16S rRNAmethylase-producing Acinetobacter baumanniiclinical strains in North America. AntimicrobAgents Chemother. 2007;51:4209-10.

Fellows Selected 1 st AuthoredPublications• Doi Y et al. Escherichia coli isolate coproducing16S rRNA Methylase and CTX-M-typeextended-spectrum beta-lactamase isolatedfrom an outpatient in the United States.Antimicrob Agents Chemother. 2008;52:1204-5.• Doi Y,et al. Community-acquired extendedspectrumbeta-lactamase producers, UnitedStates. Emerg Infect Dis. 2007;13:1121-3.

Fellows Selected 1 st AuthoredPublications• Doi Y, et al. Characterization of a naturallyoccurring class D beta-lactamase fromAchromobacter xylosoxidans. Antimicrob AgentsChemother. 2008;52:1952-6.• Doi Y, et al. Nomenclature of plasmid-mediated16S rRNA methylases responsible for panaminoglycoside resistance. Antimicrob AgentsChemother. 2008;52:2287-8.• Doi Y, et al. Genetic environment of 16S rRNAmethylase gene rmtD. Antimicrob AgentsChemother. 2008;52:2270-2.

Fellows Selected 1 st AuthoredPublications• Bhat SV, et al. Failure of current cefepimebreakpoints to predict clinical outcomes ofbacteremia caused by gram-negativeorganisms. Antimicrob Agents Chemother.2007;51:4390-5.• Bhat S, et al. Pseudomonas aeruginosainfections in the Intensive Care Unit: can theadequacy of empirical beta-lactam antibiotictherapy be improved? Int J Antimicrob Agents.2007;30:458-62.

Fellows Selected 1 st AuthoredPublications• Bhat SV, et al. Scedosporium prolificans brain abscessin a patient with chronic granulomatous disease:successful combination therapy with voriconazole andterbinafine. Scand J Infect Dis. 2007;39:87-90.• Peleg AY, et al. Acinetobacter baumannii bloodstreaminfection while receiving tigecycline: a cautionary report.JAntimicrob Chemother. 2007;59:128-31• Pelag AY, et al. Risk factors, clinical characteristics, andoutcome of Nocardia infection in organ transplantrecipients: a matched case-control study. Clin Infect Dis.2007;44:1307-14.

Fellows Selected 1 st AuthoredPublications• Silveira et al. Bloodstream infections in organtransplant recipients receiving alemtuzumab: noevidence of occurrence of organisms typicallyassociated with profound T cell depletion. JInfect. 2006;53:241-7.• Silveira F, et al. Pulmonary fungal infections.Curr Opin Pulm Med. 2005;11:242-6.• Silveira F, Fujitani S, Paterson DL. Antibioticresistantinfections in the critically ill adult. ClinLab Med. 2004;24:329-41.

Conclusion• The ID fellowhip program at UPMCprovides state-of-the-art clinical andresearch training• Our graduates are qualified to succeed inthe different venues of ID: clinical care,clinical, translational and basic research,infection control, public health

Contact UsPlease contact Kim Barnhart with questions about the InfectiousDiseases Fellowship Program. We appreciate your interest and lookforward to receiving your applicationKim Barnhart, M.Ed.Education & Fellowship CoordinatorUniversity of PittsburghDept of Medicine, Div of Infectious DiseasesFalk Medical Bldg, Suite 3A3601 Fifth AvenuePittsburgh, PA 15213-2582Tele: 412-648-6406; Fax: 412-648-6399Email: kib9@pitt.edu