888/890 Titrando - Login - Metrohm

888/890 TitrandoEnter the Titrando world

02888 Titrando – potentiometric titrator890 Titrando – Karl Fischer titrator

The advantages at a glance• Touch Control with large color screen• Titrations software tiamo TM for operation via PC• Intuitive operation• Intelligent Exchange Units• Intelligent electrodes «iTrodes» for the 888 Titrando• Potentiometric titration with the 888 Titrando• Karl Fischer titration with the 890 Titrando• Sample Processor control• Network integration via 900 Touch Control• Online help• Complies with FDA regulation 21 CFR Part 11 (with 900 Touch Control or tiamo TM full)• USB interfaces for sample changer, printer, PC keyboard, barcode reader ...03

Overview of the 888 Titrando and 890 Titrando04Intelligent dosing elements for titrationAdditional dosing elements (dispensing only)Intelligent Exchange Unit with integral datachipIncrements per cylinder volume (Exchange Unit)Measuring interface for pH, U/mV, T/°CIntelligent electrodes «iTrodes»Measuring input for polarizable electrodesOperation, dialogStirrers, titration standConnections for stirrers and intelligent dosing elementsConnection for sample changerConnections for balances, printer, PC,PC keyboard, barcode reader and/or Lab LinkTemperature sensorDifferential amplifierReal-time curve display on Touch Control or PC screenDET Dynamic equivalence-point titrationMET Monotonic equivalence-point titrationSET Titration to preset endpoints with automaticconditioningKFT Volumetric Karl Fischer titration with automaticconditioningMEAS Measuring mode for pH, U/mV, T/°C, I pol, U polCAL Calibration with automatic buffer recognitionAdditional titration curve evaluation for: fixed endpoints,pK values (HNP)Comprehensive GLP/GMP functions; complies withFDA 21 CFR Part 11888 Titrando 890 KF Titrando1 integrated Dosimat 1 integrated Dosimatfor Exchange Unit for Exchange Unit3 x 805 Dosimat 3 x 805 Dosimatwith Exchange Unit with Exchange Unit3 x 800 Dosino 3 x 800 Dosinowith Dosing Unit with Dosing UnitYes20’0001 –1 –1Touch Control or tiamo TM801 Stirrer (magnetic) or 802 Stirrer (rod) with804 Ti Stand or 803 Ti Stand (KF)4 MSB connections(Metrohm Serial Bus, Daisy Chain)1 sample changer via USBVia 2 USB Slave Ports, RS-232/USB-Box(option)Pt 1000 or NTC –Option –YesYes –Yes –Yes –– YesYes –Yes –Yes –Yes

Uniquely intelligent – easy to operateCall up the method – press startStandard user methods facilitate familiarization with thesystem and allow the Titrando to be usedimmediately. Byusing our methods you can profit from our many yearsof experience in the titration field. As storage media foryour methods, sample data and resultsthere are theTitrando itself, a USB memory stick or the PC with its nu -merous possibilitie05Intelligence creates transparencyOperating the Titrando System is simple and intuitive. Inaddition, the following tools make lifeeasier for theTitrando user:• The «Quick Access» function (direct parameters) al -lows direct access to the parameters requiredfor thegiven application. This means that it is no longer ne -cessary for you to click your waythrough differentope rating levels!• The «Help» fixed key shows a content-related helptext in the display. The «Follow me» helpfunction isavailable when working with a PC. Continuous explanationsabout the current surroundings are given in aseparate window and further possible procedures areindicated.• The standard user methods can be modified to suityour requirements. Method templates andcalculationformula templates are available for developing yourown methods. Methods can bestored under meaningfulmethod names (32 characters) and structureddirectories can be used; this makes sorting, identificationand searching much easier.• Whereas in the expert dialog all settings are available,the routine dialog can be freely configured, i.e.it can be custom-made to meet the requirements ofthe particular user.

Brainy dosing elements with certification06Metrohm’s Exchange Unit sets new standards with re -gard to reliability. Each Exchange Unit isequipped with adata chip. The Titrando automatically reads from it all thedata that it needs tocarry out the titration properly, i.e.type of reagent, titer, last titer determination, shelf-lifedata andmuch more. In addition, the Titrando comparesthe data it has obtained with the selected methodandcarries out a plausibility test. If the result is negative thena clear error message appears.In addition, each Exchange Unit is provided with serialand cylinder numbers and is supplied with a certificate ofits own. The Titrando checks the preset intervals for thetiter determination of thetitrant. This ensures that workis always carried out with the exact titer.

The iTrodes – electrodes with brainsThe electrode used for the titration is really the mostimportant component of any titration system.The iTrodesrepresent our new intelligent electrode generation andguarantee complete traceabilityof the analytical result toeach component participating in the analysis.07Digital identification – no more mix-upsThe built-in memory chip allows the storage of such im -portant sensor data as article and serialnumbers, calibrationdata, calibration history, working life and calibrationvalidity period. All thesensor data is read in automa ticallywhen the iTrode is connected to the 888 Titrando. Mixupsor editing errors are therefore eliminated. The electrodeis identified automatically. If the type ofelectrode isnot the same as that defined in the method then the useris informed. This means that it is not possible to use anincorrect electrode.Storage of calibration data – outliers have nochanceMonitoring functions allow the exclusion of electrodeswhose calibration data lies outside thelimits or whoseca lib ration period has already expired. If the sensor isused with different instruments or if you wish to preventinexperienced users from having to calibrate the electrodeon theirown instruments then the electrode can becalibrated on a different instrument under definedconditions.The calibration data stored in the chip makes theelectrode transferable; it does notneed to be recalibratedeach time that it is used with a different instrument.Compatible with all existing sensorsDespite its new digital measuring interface and intelligentsensors, the 888 Titrando with combined analog and di -gi tal measuring input also supports conventional sensors.This means that you can continue to use all your sensors.

08Karl Fischer titration withthe 890 TitrandoThe sophisticated control algorithm and the increasedvolume resolution of the 890 Titrando’s intelligent Ex -change Unit guarantee highly precise resultscombinedwith easy and intuitive user guidance.The KF icons show you at a glance whether the instrumentis still busy conditioning or whether you can startthe water determination.The iodine drop indicates the KF reagent additionduring conditioning.Conditioning is finished and the sample can beadded.The electrode test and the newly created parameter«safety stop» prevent cellrun-over during conditioning. If,for example, the electrode is not connectedcorrectly orthe titration cell is very humid, conditioning is stoppedafter a giventime or a given volume of KF reagent added.This new feature increases work safety in your labora tory.The 803 Ti Stand for KF titrationUse the 803 Ti Stand for stirring and manually exchangingthe spent titration vessel contents. With the integratedmembrane pump, solvent can be aspirated or addedwithout the cell havingto be opened. This translates intovastly reduced conditioning times.

The Titrando in the modern laboratoryTouch Control = user comfortThe Touch Control is a decidedly ergonomic and modernoperating element. Due to its USB and ethernet interfaceyou can store any data either on a USB memory stick, inyour network (as PDF file or for exporting it to yourLIMS), or you can print out this data on any printer inyour network or conncected via USB.Titrando and PC – a harmonic duoThe Titrations software tiamo TM – titration and more –opens up many other possibilities such as database functionality,parallel titration with several instruments andmuch more.If you work with tiamo TM , you can use all the storageop tions offered by the PC world, and on request theTitrando can produce a machine-readable PC/LIMS re -port.Compatibility and traceabilityThe Titrando System is entirely oriented towards qualitymanagement in the laboratory and offers thefollowingpos sibilities:• Auto-diagnostic test after switching on.• Monitoring of validation and service intervals.• Monitoring of the calibration data of sensors.• Monitoring of titers and results.• All changes to the methods are documented.• Strict control of rights of access using login andpassword, complying with FDA Regulation 21 CFRPart 11 regarding «electronic signature» and«electronic record».09

Integrated automation10Increasing sample numbers, time-consuming sample preparationsteps and unattended overnightoperation aregood reasons for using sample changers. The 888 and890 Titrandos have the necessary intelligence to controlsample changers. Whether you require small or largesample capacity, one or two working stations, sampleme tering, sample preparation, liquid handling, rinsingand calibration of the electrodes – the 814 USB SampleProcessor and 815 Robotic USB Sample ProcessorXL offera high degree of automation at low investment costs. It’samazing: You simply connect the sample changer to theTitrando’s USB port and the world of automation opensup to you. Our sample changer brochure supplies detailed information on the automation possibilities.

Subject to changeLayout by Ecknauer+Schoch ASW, printed in Switzerland by Metrohm AG, CH-9100 Herisau8.888.5002EN – 2013-03www.metrohm.com