Aquios CL - Beckman Coulter

Introducing Aquios CL...the first true Load & Go flow cytometerWhat would it mean for your laboratory’s productivity if you could automate your most routine, repetitive tasks?Modular flow cytometry systems, while effective for higher-complexity, labor-intensive applications, aren’t the bestoption for efficiently managing a high volume of routine applications for immunophenotyping such as lymphocytesubset enumeration for immunosuppressed specimens.Modular systems have, however, been the best available option – until now.

Say hello to Aquios CL from Beckman Coulter –the first true Load & Go flow cytometer.Aquios CL is easy to learn, easy to use, ideal for cross-training yourlab staff, and represents a breakthrough solution to the most basicoperational challenges of flow cytometry.With Aquios CL in your lab, Load & Go simplicitymeans you can…• Provide a 24/7 flow cytometry service as the Aquios CL can be run safely by minimallytrained users.• Minimize the potential for user error inherent in existing systems that require numerous manualsteps to set up and run.• Increase productivity with high-throughput performance that eliminates many of theleast efficient features of existing systems.• Minimize hands-on time with a fully integrated system that incorporates automated loading, samplepreparation, reagent management, barcode scanning, data analysis, and full LIS connectivity.the full spectrum ofFlow Cytometry• Get system users up to speed quickly, with one-day onsite training.• Allocate staff resources for maximum productivity, putting your skilled operators where you needthem most.• Minimize exposure to potentially biohazardous material such as open blood tubes. The Aquios CLuses cap piercing technology so that you will never have to deal with open blood tubes again.Advanced Cellular Analysis Solutions

Choose Aquios CL for end-to-end speed, simplicity, andease of use.Within its compact footprint, Aquios CL has several features that deliver powerfulperformance – and true Load & Go ease, efficiency, and savings.Full Bidirectional LIS ConnectivityAutomated System SetupSmart Track Reagent ManagementCassette Autoloader• Automatic retrieval of testrequests and transmission of testresults• No need for additional workstationsor software• No need to create or downloadworklists manually• Preprogrammed protocols in supportof applications• No fluorescent beads for setup orabsolute counts• No manual system or controlsoptimization• Power on, system warmup, loadcontrols, load samples – that’s it!• Preloaded with a range of barcodedreagents and consumables• Automatic barcode scanning totrack reagents, lot numbers, openand closed vial expiration dates, andnumber of tests left in each vial• Continuous tracking of reagentusage by product• Total capacity 40 sample tubes• Accommodates a variety of tube sizes• Continuous, random loading andunloading• Separate single-tube loader forSTAT samples, open vial samples,and/or irregular tube sizes• Future applications that aid inthe diagnosis, monitoring andtreatment of diseases arepending

Right: Smart Track reagent monitoring means allon-board reagents are barcoded for easy loading/unloading and continuous tracking of lot numbers,expiration dates, and remaining reagent levels.Touchscreen software operation makes access todot plots and histograms fast and intuitive.Below: Data analysis is performed viaadvanced automated algorithms withthe option of user-adjustable gates andregions.Above: The Aquios CL also offers single-tubeloading for STAT samples, open vials, and specimentubes that are not barcoded.Automated Sample PreparationPipeline Sample Processing*Real Time Sample MonitoringComprehensive Quality Control• Automatic matching of sampleidentification code with the testrequest• All sample preparation and analysisperformed in 96-well microplates• Automatic launch of applicabletesting protocol• Automatic dispensing and mixing ofapplicable reagents• No manual pipetting or decappingof primary tubes• Eliminate slow, inefficient batchprocessing of samples• Get the first sample result inapproximately 20 minutes ofloading and subsequent resultsevery two minutes• Two multitasking probes: one forcap piercing and samplepreparation, the other for aspiratingprepared samples for analysis• Each sample is analyzed as soon asit is ready• Intelligent analysis algorithm setsall gates and regions automatically• Intuitive software interfaceindicates the status of each sample• Know at a glance where eachsample is in the process and howmuch time until results are available• Barcode tracking means no manualQC or reagent logs• Generate a full, easily reviewableaudit trail• Should QC fail, operator is alertedvia text message or email• Future applications that aid in thediagnosis, monitoring, and treatmentof diseases pending.*Patent Pending• System flags samples that don’tmeet autovalidation criteria orrequire operator-assisted reviewthe full spectrum ofFlow Cytometry

The Aquios CL Breakthrough:Fast, efficient, high throughput, hands-off flow cytometryLearn what having true Load & Go flow cytometry capability can meanfor your laboratory’s operational and cost efficiency. Save time and money,eliminate testing backlogs, and make the most efficient use of your skilledoperators.For more information, please visit:www.aquiosnow.comAquios CL System Specifications:Dimensions:System: W: 31” (79 cm); D: 22” (56 cm); H: 22” (56 cm)Workstation: W: 23” (59cm); D: 5” (13cm); H: 18” (46cm)Supply Cart: W: 21” (54cm); D: 18” (46cm); H: 16” (41cm)Sample Loading: Autoloader holds up to 8 cassettes at a time with up to 5sample tubes each and allows for continuous loading and unloading. A separatesingle-tube loader enables both open- and closed-vial sampling.Check with your Beckman Coulter representative for a list of all compatible tubesand cassette types.Throughput: First result in approximately 20 minutes from loading.8 Parameters: 5 fluorescence detectors plus forward scatter, side scatter, andelectronic volume.*Laser: 488nm Solid State Diode LaserComputer System: All-in-one computer and monitor with touch-screen operation,plus alternative keyboard and mouse*The Electronic Volume parameter is used as a relative cellular characteristic (such as lightscatter) for the purpose of population gating and is not reported as a specific measurementof cellular volume.Aquios is in development, pending achievement of CE compliance; not yet available forin vitro diagnostic use.Aquios is not available in the U.S. Aquios is not cleared for use in In-Vitro Diagnosticapplications in the U.S.Only for distribution in the European Union and Australia.Beckman Coulter, the stylized logo, Aquios and Load & Go are trademarks of BeckmanCoulter, Inc. and are registered with the USPTO.BR-17636A B2012-13760 © 2012 Beckman Coulter, Inc.